AS 1842856 (BioDeep_00000017118)
代谢物信息卡片
化学式: C18H22FN3O3 (347.16451140000004)
中文名称: AS1842856
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCN1C=C(C(=O)C2=C1C=C(C(=C2N)F)NC3CCCCC3)C(=O)O
InChI: InChI=1S/C18H22FN3O3/c1-2-22-9-11(18(24)25)17(23)14-13(22)8-12(15(19)16(14)20)21-10-6-4-3-5-7-10/h8-10,21H,2-7,20H2,1H3,(H,24,25)
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:145800
- KEGG: C76673
- PubChem: 72193864
- ChEMBL: CHEMBL5192734
- CAS: 836620-48-5
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lai Wang, Zu-Guo Zheng, Lingchang Meng, Lijun Zhu, Ping Li, Jun Chen, Hua Yang. Statins induce skeletal muscle atrophy via GGPP depletion-dependent myostatin overexpression in skeletal muscle and brown adipose tissue.
Cell biology and toxicology.
2021 06; 37(3):441-460. doi:
10.1007/s10565-020-09558-w. [PMID: 33034787] - Di Wang, Yanqing Wang, Xiantong Zou, Yundi Shi, Qian Liu, Tianru Huyan, Jing Su, Qi Wang, Fengxue Zhang, Xuejun Li, Lu Tie. FOXO1 inhibition prevents renal ischemia-reperfusion injury via cAMP-response element binding protein/PPAR-γ coactivator-1α-mediated mitochondrial biogenesis.
British journal of pharmacology.
2020 01; 177(2):432-448. doi:
10.1111/bph.14878. [PMID: 31655022] - Suravi Majumder, Lu Ren, Sathnur Pushpakumar, Utpal Sen. Hydrogen sulphide mitigates homocysteine-induced apoptosis and matrix remodelling in mesangial cells through Akt/FOXO1 signalling cascade.
Cellular signalling.
2019 09; 61(?):66-77. doi:
10.1016/j.cellsig.2019.05.003. [PMID: 31085234] - Elena Makoveichuk, Evelina Vorrsjö, Thomas Olivecrona, Gunilla Olivecrona. TNF-α decreases lipoprotein lipase activity in 3T3-L1 adipocytes by up-regulation of angiopoietin-like protein 4.
Biochimica et biophysica acta. Molecular and cell biology of lipids.
2017 May; 1862(5):533-540. doi:
10.1016/j.bbalip.2017.02.005. [PMID: 28215713] - Megumi Ikeda, Fumiko Toyoshima. Dormant Pluripotent Cells Emerge during Neural Differentiation of Embryonic Stem Cells in a FoxO3-Dependent Manner.
Molecular and cellular biology.
2017 03; 37(5):. doi:
10.1128/mcb.00417-16. [PMID: 27956699] - Longhua Liu, Louise D Zheng, Peng Zou, Joseph Brooke, Cayleen Smith, Yun Chau Long, Fabio A Almeida, Dongmin Liu, Zhiyong Cheng. FoxO1 antagonist suppresses autophagy and lipid droplet growth in adipocytes.
Cell cycle (Georgetown, Tex.).
2016 Aug; 15(15):2033-41. doi:
10.1080/15384101.2016.1192732. [PMID: 27260854] - Shu-Jing Ju, Yuyan Zhao, Xiaocen Chang, Lei Guo. Orexin A protects cells from apoptosis by regulating FoxO1 and mTORC1 through the OX1R/PI3K/AKT signaling pathway in hepatocytes.
International journal of molecular medicine.
2014 Jul; 34(1):153-9. doi:
10.3892/ijmm.2014.1769. [PMID: 24807827] - Takeyuki Nagashima, Nobuharu Shigematsu, Riyo Maruki, Yasuharu Urano, Hirotsugu Tanaka, Akiyoshi Shimaya, Teruhiko Shimokawa, Masayuki Shibasaki. Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db mice.
Molecular pharmacology.
2010 Nov; 78(5):961-70. doi:
10.1124/mol.110.065714. [PMID: 20736318]