4-Hydroxychlorothalonil (BioDeep_00000169962)
human metabolite blood metabolite
代谢物信息卡片
2,5,6-Trichloro-4-hydroxy-1,3-benzenedicarbonitrile
化学式: C8HCl3N2O (245.9154466)
中文名称: 4 - 羟基百菌清
谱图信息:
最多检出来源 Homo sapiens(blood) 8.3%
分子结构信息
SMILES: C(#N)C1=C(C(=C(C(=C1Cl)C#N)Cl)Cl)O
InChI: InChI=1S/C8HCl3N2O/c9-5-3(1-12)6(10)7(11)8(14)4(5)2-13/h14H
描述信息
4-Hydroxychlorothalonil (SDS 3701) is a metabolite of the widely used fungicide chlorothalonil which is used to manage fungal diseases affecting agricultural crops around the world (PMID: 31265862). 4-Hydroxychlorothalonil was identified as one of forty plasma metabolites that could be used to predict gut microbiome Shannon diversity (PMID: 31477923). Shannon diversity is a metric that summarizes both species abundance and evenness, and it has been suggested as a marker for microbiome health.
D010575 - Pesticides > D008975 - Molluscacides
D016573 - Agrochemicals
同义名列表
15 个代谢物同义名
2,5,6-Trichloro-4-hydroxy-1,3-benzenedicarbonitrile; 2,4,5-trichloro-6-hydroxybenzene-1,3-dicarbonitrile; 4-Hydroxy-2,5,6-trichloro-1,3-benzenedicarbonitrile; 2,4,5-Trichloro-6-hydroxy-1,3-benzenedicarbonitrile; 1,3-Dicyano-4-hydroxy-2,5,6-trichlorobenzene; 4-Hydroxy-2,5,6-trichloroisophthalonitrile; 2,4,5-Trichloro-6-hydroxyisophthalonitrile; Tetrachloroisophthalonitrile; 4-Hydroxychlorothalonil; Hydroxy Chlorothalonil; Hydroxychlorothalonil; Chlorothalonil; SDS 3701; Daconil; Bravo
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:133542
- PubChem: 34217
- HMDB: HMDB0240624
- ChEMBL: CHEMBL3248146
- chemspider: 31530
- CAS: 28343-61-5
- RefMet: 4-Hydroxychlorothalonil
- RefMet: Hydroxychlorothalonil
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jun Su Noh, Seo Hyun Hwang, Chaw Ei Htwe Maung, Jeong-Yong Cho, Kil Yong Kim. Enhanced control efficacy of Bacillus subtilis NM4 via integration of chlorothalonil on potato early blight caused by Alternaria solani.
Microbial pathogenesis.
2024 May; 190(?):106604. doi:
10.1016/j.micpath.2024.106604. [PMID: 38490458] - Seher Yolcu, Monika Skorupa, Mehmet Emin Uras, Justyna Mazur, Ibrahim Ilker Ozyiğit. Genome-wide identification, phylogenetic classification of histone acetyltransferase genes, and their expression analysis in sugar beet (Beta vulgaris L.) under salt stress.
Planta.
2024 Mar; 259(4):85. doi:
10.1007/s00425-024-04361-x. [PMID: 38448714] - Tainá Guillante, Yuri Dornelles Zebral, Dennis Guilherme da Costa Silva, Antonio Sergio Varela Junior, Carine Dahl Corcini, Izani Bonel Acosta, Patrícia Gomes Costa, Adalto Bianchini, Carlos Eduardo da Rosa. Chlorothalonil as a potential endocrine disruptor in male zebrafish (Danio rerio): Impact on the hypothalamus-pituitary-gonad axis and sperm quality.
Chemosphere.
2024 Mar; 352(?):141423. doi:
10.1016/j.chemosphere.2024.141423. [PMID: 38340991] - Tong Wu, Jing Gao, Yong Soo Choi, Dong Won Kim, Bo Han, Sa Yang, Ying Lu, Yuxin Kang, Hanchao Du, Qingyun Diao, Pingli Dai. Interaction of chlorothalonil and Varroa destructor on immature honey bees rearing in vitro.
The Science of the total environment.
2023 Dec; 904(?):166302. doi:
10.1016/j.scitotenv.2023.166302. [PMID: 37595923] - Gao-Bo Yu, Jin Tian, Ru-Nan Chen, Han-Lin Liu, Bo-Wen Wen, Jin-Peng Wei, Qiu-Sen Chen, Feng-Qiong Chen, Yun-Yan Sheng, Feng-Jun Yang, Chun-Yuan Ren, Yu-Xian Zhang, Golam Jalal Ahammed. Glutathione-dependent redox homeostasis is critical for chlorothalonil detoxification in tomato leaves.
Ecotoxicology and environmental safety.
2023 Dec; 268(?):115732. doi:
10.1016/j.ecoenv.2023.115732. [PMID: 38000301] - Chi Zhang, Heli Li, Huijing Shen, Bing Lyu, Shaohua Li, Jingguang Li, Yunfeng Zhao, Dawei Chen, Yongning Wu. Chronic Health Risk for Chinese Adults and Breastfed Infants on Dietary Exposure to Chlorothalonil and Its Main Metabolite.
Journal of agricultural and food chemistry.
2023 Jul; 71(26):10169-10177. doi:
10.1021/acs.jafc.3c02512. [PMID: 37342977] - Koonlawee Nademanee, Fa-Po Chung, Frederic Sacher, Akihiko Nogami, Hiroshi Nakagawa, Chenyang Jiang, Meleze Hocini, Elijah Behr, Gumpanart Veerakul, Jaap Jan Smit, Arthur A M Wilde, Shih-Ann Chen, Kohei Yamashiro, Yuichiro Sakamoto, Itsuro Morishima, Mithilesh K Das, Apichai Khongphatthanayothin, Saran Vardhanabhuti, Michel Haissaguerre. Long-Term Outcomes of Brugada Substrate Ablation: A Report from BRAVO (Brugada Ablation of VF Substrate Ongoing Multicenter Registry).
Circulation.
2023 05; 147(21):1568-1578. doi:
10.1161/circulationaha.122.063367. [PMID: 36960730] - Zhiyuan Meng, Sen Yan, Wei Sun, Jin Yan, Miaomiao Teng, Ming Jia, Sinuo Tian, Zhiqiang Zhou, Wentao Zhu. Chlorothalonil induces obesity in mice by regulating host gut microbiota and bile acids metabolism via FXR pathways.
Journal of hazardous materials.
2023 Mar; 452(?):131310. doi:
10.1016/j.jhazmat.2023.131310. [PMID: 37003002] - Lucas Gonçalves Morais, Paloma Kachel Gusso-Choueri, Fiamma Eugênia Lemos Abreu, Ítalo Braga Castro, Denis Moledo Abessa, Rodrigo Brasil Choueri. Multilevel assessment of chlorothalonil sediment toxicity to Latin American estuarine biota: Effects on biomarkers, reproduction and survival in different benthic organisms.
The Science of the total environment.
2023 Feb; ?(?):162215. doi:
10.1016/j.scitotenv.2023.162215. [PMID: 36791867] - Xiaohua Peng, Nannan Wang, Shuangsheng Sun, Lijiahong Geng, Ning Guo, Airong Liu, Shuangchen Chen, Golam Jalal Ahammed. Reactive oxygen species signaling is involved in melatonin-induced reduction of chlorothalonil residue in tomato leaves.
Journal of hazardous materials.
2023 Feb; 443(Pt A):130212. doi:
10.1016/j.jhazmat.2022.130212. [PMID: 36308936] - Jacquelyn A Perkins, Kyungmin Kim, Larry J Gut, George W Sundin, Julianna K Wilson. Fungicide Exposure in Honey Bee Hives Varies By Time, Worker Role, and Proximity to Orchards in Spring.
Journal of economic entomology.
2023 Jan; ?(?):. doi:
10.1093/jee/toad008. [PMID: 36708024] - Nan Li, Yining Xia, Yanyang Xu, Yun Li, Qi Jia, Jing Qiu, Yongzhong Qian, Zian Wang, Zhe Liu. Identification and analysis of the degradation products of chlorothalonil in vegetables.
Journal of chromatography. A.
2022 Dec; 1686(?):463647. doi:
10.1016/j.chroma.2022.463647. [PMID: 36413910] - Guolei Shan, Meiqing Zhu, Dong Zhang, Taozhong Shi, Jialong Song, Qing X Li, Rimao Hua. Effects of plant morphology, vitamin C, and other co-present pesticides on the deposition, dissipation, and metabolism of chlorothalonil in pakchoi.
Environmental science and pollution research international.
2022 Dec; 29(56):84762-84772. doi:
10.1007/s11356-022-21405-5. [PMID: 35789467] - Isaack Kikway, Anthony P Keinath, Peter S Ojiambo. Within-season Shift in Fungicide Sensitivity Profiles of Pseudoperonospora cubensis Populations in Response to Chemical Control.
Plant disease.
2022 Oct; ?(?):. doi:
10.1094/pdis-09-22-2056-re. [PMID: 36205688] - Josep Mercadal, Isabel Betegón-Putze, Nadja Bosch, Ana I Caño-Delgado, Marta Ibañes. BRAVO self-confined expression through WOX5 in the Arabidopsis root stem-cell niche.
Development (Cambridge, England).
2022 08; 149(15):. doi:
10.1242/dev.200510. [PMID: 35899779] - Qibao He, Qing Yang, Qiongqiong Liu, Zhaoyin Hu, Quan Gao, Yongcheng Dong, Jinjing Xiao, Linsheng Yu, Haiqun Cao. The effects of beta-cypermethrin, chlorbenzuron, chlorothalonil, and pendimethalin on Apis mellifera ligustica and Apis cerana cerana larvae reared in vitro.
Pest management science.
2022 Apr; 78(4):1407-1416. doi:
10.1002/ps.6757. [PMID: 34897947] - Murtaza Ali, Da-Wen Sun, Jun-Hu Cheng, Okon Johnson Esua. Effects of combined treatment of plasma activated liquid and ultrasound for degradation of chlorothalonil fungicide residues in tomato.
Food chemistry.
2022 Mar; 371(?):131162. doi:
10.1016/j.foodchem.2021.131162. [PMID: 34600368] - Yueqiao Wang, Tong Zhang, Jun Wang, Sheng Xu, Wenbiao Shen. Regulation of chlorothalonil degradation by molecular hydrogen.
Journal of hazardous materials.
2022 Feb; 424(Pt A):127291. doi:
10.1016/j.jhazmat.2021.127291. [PMID: 34583156] - Victor Razuk, Anton Camaj, Davide Cao, Johny Nicolas, Christian Hengstenberg, Samantha Sartori, Zhongjie Zhang, David Power, Frans Beerkens, Mauro Chiarito, Nicolas Meneveau, Christophe Tron, Nicolas Dumonteil, Julian D Widder, Markus Ferrari, Roberto Violini, Pieter R Stella, Raban Jeger, Prodromos Anthopoulos, Roxana Mehran, George D Dangas. Impact of anemia on short-term outcomes after TAVR: A subgroup analysis from the BRAVO-3 randomized trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.
2021 11; 98(6):E870-E880. doi:
10.1002/ccd.29753. [PMID: 33909348] - Xiaojing Li, Xia Zhao, Yujie Yao, Mengyao Guo, Shu Li. New insights into crosstalk between apoptosis and necroptosis co-induced by chlorothalonil and imidacloprid in Ctenopharyngodon idellus kidney cells.
The Science of the total environment.
2021 Aug; 780(?):146591. doi:
10.1016/j.scitotenv.2021.146591. [PMID: 33770597] - Isabel Betegón-Putze, Josep Mercadal, Nadja Bosch, Ainoa Planas-Riverola, Mar Marquès-Bueno, Josep Vilarrasa-Blasi, David Frigola, Rebecca C Burkart, Cristina Martínez, Ana Conesa, Rosangela Sozzani, Yvonne Stahl, Salomé Prat, Marta Ibañes, Ana I Caño-Delgado. Precise transcriptional control of cellular quiescence by BRAVO/WOX5 complex in Arabidopsis roots.
Molecular systems biology.
2021 06; 17(6):e9864. doi:
10.15252/msb.20209864. [PMID: 34132490] - P B Reyna, M L Albá, F A Rodríguez, M Gonzalez, C Pegoraro, A C Hued, M Tatián, M L Ballesteros. What does the freshwater clam, Corbicula largillierti, have to tell us about chlorothalonil effects?.
Ecotoxicology and environmental safety.
2021 Jan; 208(?):111603. doi:
10.1016/j.ecoenv.2020.111603. [PMID: 33396123] - Xiaojing Li, Yujie Yao, Shengchen Wang, Shiwen Xu. Resveratrol relieves chlorothalonil-induced apoptosis and necroptosis through miR-15a/Bcl2-A20 axis in fish kidney cells.
Fish & shellfish immunology.
2020 Dec; 107(Pt B):427-434. doi:
10.1016/j.fsi.2020.11.007. [PMID: 33186708] - Jake G Jones, Robert C Korir, Taylor L Walter, Kathryne L Everts. Reducing Chlorothalonil Use in Fungicide Spray Programs for Powdery Mildew, Anthracnose, and Gummy Stem Blight in Melons.
Plant disease.
2020 Dec; 104(12):3213-3220. doi:
10.1094/pdis-04-20-0712-re. [PMID: 33079017] - Enze Sheng, Yuxiao Lu, Yuting Tan, Yue Xiao, Zhenxi Li, Zhihui Dai. Oxidase-mimicking activity of ultrathin MnO2 nanosheets in a colorimetric assay of chlorothalonil in food samples.
Food chemistry.
2020 Nov; 331(?):127090. doi:
10.1016/j.foodchem.2020.127090. [PMID: 32593035] - Ling Zhao, Yan Li, Wenjie Ren, Yang Huang, Xiaomi Wang, Zhaocong Fu, Wenting Ma, Ying Teng, Yongming Luo. Pesticide residues in soils planted with Panax notoginseng in south China, and their relationships in Panax notoginseng and soil.
Ecotoxicology and environmental safety.
2020 Sep; 201(?):110783. doi:
10.1016/j.ecoenv.2020.110783. [PMID: 32534333] - Juliano da Silva Barreto, Fabio de Melo Tarouco, Carlos Eduardo da Rosa. Chlorothalonil causes redox state change leading to oxidative stress generation in Danio rerio.
Aquatic toxicology (Amsterdam, Netherlands).
2020 Aug; 225(?):105527. doi:
10.1016/j.aquatox.2020.105527. [PMID: 32599436] - Enze Sheng, Yuxiao Lu, Yuting Tan, Yue Xiao, Zhenxi Li, Zhihui Dai. Ratiometric Fluorescent Quantum Dot-Based Biosensor for Chlorothalonil Detection via an Inner-Filter Effect.
Analytical chemistry.
2020 03; 92(6):4364-4370. doi:
10.1021/acs.analchem.9b05199. [PMID: 32050759] - Amanda da Silveira Guerreiro, Fiamma Eugênia Lemos Abreu, Gilberto Fillmann, Juliana Zomer Sandrini. Effects of chlorothalonil on the antioxidant defense system of mussels Perna perna.
Ecotoxicology and environmental safety.
2020 Mar; 190(?):110119. doi:
10.1016/j.ecoenv.2019.110119. [PMID: 31891835] - Jaqueline N DA Silva, Nayara R Monteiro, Patricia A Antunes, Ana Paula A Favareto. Maternal and developmental toxicity after exposure to formulation of chlorothalonil and thiophanate-methyl during organogenesis in rats.
Anais da Academia Brasileira de Ciencias.
2020; 92(4):e20191026. doi:
10.1590/0001-3765202020191026. [PMID: 33206784] - Anna Barbasz, Barbara Kreczmer, Magdalena Skórka, Agnieszka Czyżowska. Toxicity of pesticides toward human immune cells U-937 and HL-60.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2020; 55(8):719-725. doi:
10.1080/03601234.2020.1777059. [PMID: 32538258] - Jiayin Hou, Qian Sun, Junjie Li, Golam Jalal Ahammed, Jingquan Yu, Hua Fang, Xiaojian Xia. Glutaredoxin S25 and its interacting TGACG motif-binding factor TGA2 mediate brassinosteroid-induced chlorothalonil metabolism in tomato plants.
Environmental pollution (Barking, Essex : 1987).
2019 Dec; 255(Pt 2):113256. doi:
10.1016/j.envpol.2019.113256. [PMID: 31563783] - Saichao Gao, Guobin Wang, Yangyang Zhou, Ming Wang, Daibin Yang, Huizhu Yuan, Xiaojing Yan. Water-soluble food dye of Allura Red as a tracer to determine the spray deposition of pesticide on target crops.
Pest management science.
2019 Oct; 75(10):2592-2597. doi:
10.1002/ps.5430. [PMID: 30927304] - Xinhang Yang, Brian Bennett, Richard C Holz. Insights into the catalytic mechanism of a bacterial hydrolytic dehalogenase that degrades the fungicide chlorothalonil.
The Journal of biological chemistry.
2019 09; 294(36):13411-13420. doi:
10.1074/jbc.ra119.009094. [PMID: 31331935] - Verena Christen, Jana Krebs, Karl Fent. Fungicides chlorothanolin, azoxystrobin and folpet induce transcriptional alterations in genes encoding enzymes involved in oxidative phosphorylation and metabolism in honey bees (Apis mellifera) at sublethal concentrations.
Journal of hazardous materials.
2019 09; 377(?):215-226. doi:
10.1016/j.jhazmat.2019.05.056. [PMID: 31170570] - Alondra M Díaz Rodríguez, Fannie I Parra Cota, Gustavo Santoyo, Sergio de Los Santos Villalobos. Chlorothalonil tolerance of indole producing bacteria associated to wheat (Triticum turgidum L.) rhizosphere in the Yaqui Valley, Mexico.
Ecotoxicology (London, England).
2019 Jul; 28(5):569-577. doi:
10.1007/s10646-019-02053-x. [PMID: 31129746] - Scott T O'Neal, Alison M Reeves, Richard D Fell, Carlyle C Brewster, Troy D Anderson. Chlorothalonil Exposure Alters Virus Susceptibility and Markers of Immunity, Nutrition, and Development in Honey Bees.
Journal of insect science (Online).
2019 May; 19(3):. doi:
10.1093/jisesa/iez051. [PMID: 31120492] - Małgorzata Baćmaga, Jadwiga Wyszkowska, Jan Kucharski. The influence of chlorothalonil on the activity of soil microorganisms and enzymes.
Ecotoxicology (London, England).
2018 Nov; 27(9):1188-1202. doi:
10.1007/s10646-018-1968-7. [PMID: 30173333] - Jennifer M Foster, Mary Ruth McDonald. Evaluation of the TOM-CAST Forecasting Model in Asparagus for Management of Stemphylium Leaf Spot in Ontario, Canada.
Plant disease.
2018 11; 102(11):2253-2257. doi:
10.1094/pdis-10-17-1631-re. [PMID: 30145949] - Guopeng Miao, Juan Han, Tao Ye, Zhina Chen, Kegui Zhang. Efficiency and Safety Assurance of Six Fungicides Applied on Postharvest Cabbages Stored in a Natural Environment.
Journal of agricultural and food chemistry.
2018 Oct; 66(41):10864-10870. doi:
10.1021/acs.jafc.8b03910. [PMID: 30272962] - Robert Green, Hyunkyu Sang, Jeongdae Im, Geunhwa Jung. Chlorothalonil biotransformation by cytochrome P450 monooxygenases in Sclerotinia homoeocarpa.
FEMS microbiology letters.
2018 10; 365(19):. doi:
10.1093/femsle/fny214. [PMID: 30184177] - Justin Clements, Sean Schoville, Anna Clements, Dries Amezian, Tabatha Davis, Benjamin Sanchez-Sedillo, Christopher Bradfield, Anders S Huseth, Russell L Groves. Agricultural fungicides inadvertently influence the fitness of Colorado potato beetles, Leptinotarsa decemlineata, and their susceptibility to insecticides.
Scientific reports.
2018 09; 8(1):13282. doi:
10.1038/s41598-018-31663-4. [PMID: 30185821] - Jiayin Hou, Qihao Zhang, Yue Zhou, Golam Jalal Ahammed, Yanhong Zhou, Jingquan Yu, Hua Fang, Xiaojian Xia. Glutaredoxin GRXS16 mediates brassinosteroid-induced apoplastic H2O2 production to promote pesticide metabolism in tomato.
Environmental pollution (Barking, Essex : 1987).
2018 Sep; 240(?):227-234. doi:
10.1016/j.envpol.2018.04.120. [PMID: 29747107] - Gilvani Carla Mallmann, José Paulo Sousa, Ingvar Sundh, Silvia Pieper, Maria Arena, Sonia Purin da Cruz, Osmar Klauberg-Filho. Placing arbuscular mycorrhizal fungi on the risk assessment test battery of plant protection products (PPPs).
Ecotoxicology (London, England).
2018 Sep; 27(7):809-818. doi:
10.1007/s10646-018-1946-0. [PMID: 29802487] - Haijie Ma, Mingshuang Wang, Yunpeng Gai, Huilan Fu, Bin Zhang, Ruoxin Ruan, Kuang-Ren Chung, Hongye Li. Thioredoxin and Glutaredoxin Systems Required for Oxidative Stress Resistance, Fungicide Sensitivity, and Virulence of Alternaria alternata.
Applied and environmental microbiology.
2018 07; 84(14):. doi:
10.1128/aem.00086-18. [PMID: 29752269] - Xiangmin Song, Chunjuan Liu, Peiqi Chen, Hao Zhang, Ranfeng Sun. Natural Product-Based Pesticide Discovery: Design, Synthesis and Bioactivity Studies of N-Amino-Maleimide Derivatives.
Molecules (Basel, Switzerland).
2018 06; 23(7):. doi:
10.3390/molecules23071521. [PMID: 29937519] - Juliano da Silva Barreto, Fabio de Melo Tarouco, Filipe Guilherme Andrade de Godoi, Márcio Alberto Geihs, Fiamma Eugenia Lemos Abreu, Gilberto Fillmann, Juliana Zomer Sandrini, Carlos Eduardo da Rosa. Induction of oxidative stress by chlorothalonil in the estuarine polychaete Laeonereis acuta.
Aquatic toxicology (Amsterdam, Netherlands).
2018 Mar; 196(?):1-8. doi:
10.1016/j.aquatox.2017.12.004. [PMID: 29310040] - Justin Clements, Benjamin Sanchez-Sedillo, Christopher A Bradfield, Russell L Groves. Transcriptomic analysis reveals similarities in genetic activation of detoxification mechanisms resulting from imidacloprid and chlorothalonil exposure.
PloS one.
2018; 13(10):e0205881. doi:
10.1371/journal.pone.0205881. [PMID: 30359414] - Yigal Cohen, Avia Evgenia Rubin, Mariana Galperin. Oxathiapiprolin-based fungicides provide enhanced control of tomato late blight induced by mefenoxam-insensitive Phytophthora infestans.
PloS one.
2018; 13(9):e0204523. doi:
10.1371/journal.pone.0204523. [PMID: 30260986] - Pengqiang Du, Xiaohu Wu, Hairong He, Ying Zhang, Jun Xu, Fengshou Dong, Yongquan Zheng, Xingang Liu. Evaluation of the safe use and dietary risk of beta-cypermethrin, pyriproxyfen, avermectin, diflubenzuron and chlorothalonil in button mushroom.
Scientific reports.
2017 08; 7(1):8694. doi:
10.1038/s41598-017-07860-y. [PMID: 28821721] - Michael Méndez, Priscilla Obando, Margaret Pinnock-Branford, Clemens Ruepert, Luisa E Castillo, Freylan Mena, Gilbert Alvarado. Acute, chronic and biochemical effects of chlorothalonil on Agalychnis callidryas, Isthmohyla pseudopuma and Smilisca baudinii tadpoles.
Environmental science and pollution research international.
2016 Nov; 23(21):21238-21248. doi:
10.1007/s11356-016-7301-1. [PMID: 27495920] - Magdalena Jankowska, Piotr Kaczynski, Izabela Hrynko, Bozena Lozowicka. Dissipation of six fungicides in greenhouse-grown tomatoes with processing and health risk.
Environmental science and pollution research international.
2016 Jun; 23(12):11885-900. doi:
10.1007/s11356-016-6260-x. [PMID: 26957431] - Glen R Obear, Adekunle W Adesanya, Patrick J Liesch, R Chris Williamson, David W Held. Fungicides affect Japanese beetle Popillia japonica (Coleoptera: Scarabaeidae) egg hatch, larval survival and detoxification enzymes.
Pest management science.
2016 May; 72(5):966-73. doi:
10.1002/ps.4076. [PMID: 26171954] - Avat Shekoofa, Pablo Rosas-Anderson, Danesha S Carley, Thomas R Sinclair, Thomas W Rufty. Limited transpiration under high vapor pressure deficits of creeping bentgrass by application of Daconil-Action.
Planta.
2016 Feb; 243(2):421-7. doi:
10.1007/s00425-015-2417-y. [PMID: 26438219] - Yuki Hirakawa, Tomomi Yamasaki, Eiki Watanabe, Fumiko Okazaki, Yukie Murakami-Yamaguchi, Masayuki Oda, Seiji Iwasa, Hiroshi Narita, Shiro Miyake. Development of an Immunosensor for Determination of the Fungicide Chlorothalonil in Vegetables, Using Surface Plasmon Resonance.
Journal of agricultural and food chemistry.
2015 Jul; 63(28):6325-30. doi:
10.1021/acs.jafc.5b01980. [PMID: 26172540] - Yanhong Zhou, Xiaojian Xia, Gaobo Yu, Jitao Wang, Jingxue Wu, Mengmeng Wang, Youxin Yang, Kai Shi, Yunlong Yu, Zhixiang Chen, Jay Gan, Jingquan Yu. Brassinosteroids play a critical role in the regulation of pesticide metabolism in crop plants.
Scientific reports.
2015 Mar; 5(?):9018. doi:
10.1038/srep09018. [PMID: 25761674] - Ren-dong Ji, Zhi-min Zhao, Meng-lan Chen, Le-xin Wang, Xing-yue Zhu. Study on fluorescence spectra of chlorothalonil residues and the interaction between chlorothalonil and Chinese herbal medicines.
Guang pu xue yu guang pu fen xi = Guang pu.
2015 Feb; 35(2):415-9. doi:
". [PMID: 25970903] - Christopher J Pulliam, Ryan M Bain, Joshua S Wiley, Zheng Ouyang, R Graham Cooks. Mass spectrometry in the home and garden.
Journal of the American Society for Mass Spectrometry.
2015 Feb; 26(2):224-30. doi:
10.1007/s13361-014-1056-z. [PMID: 25510934] - Alessandra Gallo, Elisabetta Tosti. Reprotoxicity of the antifoulant chlorothalonil in ascidians: an ecological risk assessment.
PloS one.
2015; 10(4):e0123074. doi:
10.1371/journal.pone.0123074. [PMID: 25875759] - Yongqiang Tan, Qinghua Huang, Taozhong Shi, Laijia Jin, Rimao Hua, Xiangwei Wu, Xiangqiong Li, Xuede Li, Haiqun Cao, Jun Tang, Qing X Li. Promoting photosensitized reductive dechlorination of chlorothalonil using epigallocatechin gallate in water.
Journal of agricultural and food chemistry.
2014 Dec; 62(50):12090-5. doi:
10.1021/jf504565b. [PMID: 25423043] - Xiangwei Wu, Yuanming Yin, Shaoyun Wang, Yunlong Yu. Accumulation of chlorothalonil and its metabolite, 4-hydroxychlorothalonil, in soil after repeated applications and its effects on soil microbial activities under greenhouse conditions.
Environmental science and pollution research international.
2014 Mar; 21(5):3452-9. doi:
10.1007/s11356-013-2318-1. [PMID: 24243264] - Pengqiang Du, Xingang Liu, Xiaojun Gu, Fengshou Dong, Jun Xu, Zhiqiang Kong, Yuanbo Li, Yongquan Zheng. Residue behaviour of six pesticides in button crimini during home canning.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2014; 31(6):1081-8. doi:
10.1080/19440049.2014.910314. [PMID: 24761834] - Ai-Ying Guan, Chang-Ling Liu, Guang Huang, Hui-Chao Li, Shu-Lin Hao, Ying Xu, Zhi-Nian Li. Design, synthesis, and structure-activity relationship of novel aniline derivatives of chlorothalonil.
Journal of agricultural and food chemistry.
2013 Dec; 61(49):11929-36. doi:
10.1021/jf403739e. [PMID: 24255942] - Zhi-Wei Wang, Jiexun Huang, Jin-Yuan Chen, Fei-Li Li. Time-dependent movement and distribution of chlorothalonil and chlorpyrifos in tomatoes.
Ecotoxicology and environmental safety.
2013 Jul; 93(?):107-11. doi:
10.1016/j.ecoenv.2013.03.037. [PMID: 23639722] - Yong Qiang Tan, Hai Xia Xiong, Tao Zhong Shi, Ri Mao Hua, Xiang Wei Wu, Hai Qun Cao, Xue De Li, Jun Tang. Photosensitizing effects of nanometer TiO2 on chlorothalonil photodegradation in aqueous solution and on the surface of pepper.
Journal of agricultural and food chemistry.
2013 May; 61(21):5003-8. doi:
10.1021/jf4006005. [PMID: 23646907] - Gao-Bo Yu, Yang Zhang, Golam Jalal Ahammed, Xiao-Jian Xia, Wei-Hua Mao, Kai Shi, Yan-Hong Zhou, Jing-Quan Yu. Glutathione biosynthesis and regeneration play an important role in the metabolism of chlorothalonil in tomato.
Chemosphere.
2013 Mar; 90(10):2563-70. doi:
10.1016/j.chemosphere.2012.10.100. [PMID: 23219050] - Zachery R Staley, Jacob K Senkbeil, Jason R Rohr, Valerie J Harwood. Lack of direct effects of agrochemicals on zoonotic pathogens and fecal indicator bacteria.
Applied and environmental microbiology.
2012 Nov; 78(22):8146-50. doi:
10.1128/aem.01815-12. [PMID: 22961900] - Xiangwei Wu, Longyin Cheng, Zhengya Cao, Yunlong Yu. Accumulation of chlorothalonil successively applied to soil and its effect on microbial activity in soil.
Ecotoxicology and environmental safety.
2012 Jul; 81(?):65-9. doi:
10.1016/j.ecoenv.2012.04.017. [PMID: 22571947] - Kondreddy Anil, Appa Rao Podile. HarpinPss-mediated enhancement in growth and biological control of late leaf spot in groundnut by a chlorothalonil-tolerant Bacillus thuringiensis SFC24.
Microbiological research.
2012 Apr; 167(4):194-8. doi:
10.1016/j.micres.2011.07.002. [PMID: 21831618] - P Budai, R Szabó, J Lehel, E Kormos, A Takács, A Tatai, G Somody. Toxicity of chlorothalonil containing formulation and Cu-sulphate to chicken.
Communications in agricultural and applied biological sciences.
2012; 77(4):449-54. doi:
. [PMID: 23885413] - Christine Garron, Bill Ernst, Gary Julien, René Losier, Kimberly Davis. Concentrations and environmental risk of chlorothalonil in air near potato fields in Prince Edward Island, Canada.
Pest management science.
2012 Jan; 68(1):92-100. doi:
10.1002/ps.2228. [PMID: 21710553] - S Monadjemi, M El Roz, C Richard, A Ter Halle. Photoreduction of chlorothalonil fungicide on plant leaf models.
Environmental science & technology.
2011 Nov; 45(22):9582-9. doi:
10.1021/es202400s. [PMID: 21950599] - Peter Fantke, Raphaël Charles, Luiz Felippe de Alencastro, Rainer Friedrich, Olivier Jolliet. Plant uptake of pesticides and human health: dynamic modeling of residues in wheat and ingestion intake.
Chemosphere.
2011 Nov; 85(10):1639-47. doi:
10.1016/j.chemosphere.2011.08.030. [PMID: 21955352] - P Chris Wilson, Catherine Riiska, Joseph P Albano. Nontarget deposition and losses of chlorothalonil in irrigation runoff water from a commercial foliage plant nursery.
Journal of environmental quality.
2010 Nov; 39(6):2130-7. doi:
10.2134/jeq2010.0221. [PMID: 21284311] - Jitao Wang, Yuping Jiang, Shuangchen Chen, Xiaojian Xia, Kai Shi, Yanhong Zhou, Yunlong Yu, Jingquan Yu. The different responses of glutathione-dependent detoxification pathway to fungicide chlorothalonil and carbendazim in tomato leaves.
Chemosphere.
2010 May; 79(9):958-65. doi:
10.1016/j.chemosphere.2010.02.020. [PMID: 20347472] - Carole Bedos, Marie-France Rousseau-Djabri, Benjamin Loubet, Brigitte Durand, Dominique Flura, Olivier Briand, Enrique Barriuso. Fungicide volatilization measurements: inverse modeling, role of vapor pressure, and state of foliar residue.
Environmental science & technology.
2010 Apr; 44(7):2522-8. doi:
10.1021/es9030547. [PMID: 20199019] - Paul M White, Thomas L Potter, Albert K Culbreath. Fungicide dissipation and impact on metolachlor aerobic soil degradation and soil microbial dynamics.
The Science of the total environment.
2010 Feb; 408(6):1393-402. doi:
10.1016/j.scitotenv.2009.11.012. [PMID: 20015538] - J Hellou, A Cook, B Lalonde, P Walker, K Dunphy, S MacLeod. Escape and survival of Corophium volutator and Ilyanassa obsoleta exposed to freshwater and chlorothalonil.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.
2009 Jul; 44(8):778-90. doi:
10.1080/10934520902928404. [PMID: 19731835] - Lesley K Shelley, Shannon K Balfry, Peter S Ross, Christopher J Kennedy. Immunotoxicological effects of a sub-chronic exposure to selected current-use pesticides in rainbow trout (Oncorhynchus mykiss).
Aquatic toxicology (Amsterdam, Netherlands).
2009 Apr; 92(2):95-103. doi:
10.1016/j.aquatox.2009.01.005. [PMID: 19237205] - Julie Pariseau, Richard Saint-Louis, Maryse Delaporte, Mohammed Abo El Khair, Patricia McKenna, Réjean Tremblay, T Jeffrey Davidson, Emilien Pelletier, Franck C J Berthe. Potential link between exposure to fungicides chlorothalonil and mancozeb and haemic neoplasia development in the soft-shell clam Mya arenaria: a laboratory experiment.
Marine pollution bulletin.
2009 Apr; 58(4):503-14. doi:
10.1016/j.marpolbul.2008.12.011. [PMID: 19157463] - J D M Belgers, G H Aalderink, P J Van den Brink. Effects of four fungicides on nine non-target submersed macrophytes.
Ecotoxicology and environmental safety.
2009 Feb; 72(2):579-84. doi:
10.1016/j.ecoenv.2008.06.005. [PMID: 18703229] - Xiaoqiang Chu, Hua Fang, Xuedong Pan, Xiao Wang, Min Shan, Bo Feng, Yunlong Yu. Degradation of chlorpyrifos alone and in combination with chlorothalonil and their effects on soil microbial populations.
Journal of environmental sciences (China).
2008; 20(4):464-9. doi:
10.1016/s1001-0742(08)62080-x. [PMID: 18575132] - Alicia Chaves, Damian Shea, W Gregory Cope. Environmental fate of chlorothalonil in a Costa Rican banana plantation.
Chemosphere.
2007 Oct; 69(7):1166-74. doi:
10.1016/j.chemosphere.2007.03.048. [PMID: 17498771] - Carlos N A Hernández-Hernández, Javier Valle-Mora, Antonio Santiesteban-Hernández, Ricardo Bello-Mendoza. Comparative ecological risks of pesticides used in plantation production of papaya: application of the SYNOPS indicator.
The Science of the total environment.
2007 Aug; 381(1-3):112-25. doi:
10.1016/j.scitotenv.2007.03.014. [PMID: 17482661] - Xu-hong Zhang, Ai-jun Lin, Yu-jing Cui. [Effects of arbuscular mycorrhizal fungi on the toxicity of chlorothalonil on upland rice (Oryzal sativa L.)].
Huan jing ke xue= Huanjing kexue.
2007 May; 28(5):1107-12. doi:
". [PMID: 17633187] - Minze Leistra, Frederik van den Berg. Volatilization of parathion and chlorothalonil from a potato crop simulated by the PEARL model.
Environmental science & technology.
2007 Apr; 41(7):2243-8. doi:
10.1021/es0627242. [PMID: 17438770] - Yun Long Yu, Min Shan, Hua Fang, Xiao Wang, Xiao Qiang Chu. Responses of soil microorganisms and enzymes to repeated applications of chlorothalonil.
Journal of agricultural and food chemistry.
2006 Dec; 54(26):10070-5. doi:
10.1021/jf0624190. [PMID: 17177543] - Xu-Hong Zhang, Yong-Guan Zhu, Ai-Jun Lin, Bao-Dong Chen, Sally E Smith, F Andrew Smith. Arbuscular mycorrhizal fungi can alleviate the adverse effects of chlorothalonil on Oryza sativa L.
Chemosphere.
2006 Sep; 64(10):1627-32. doi:
10.1016/j.chemosphere.2006.01.034. [PMID: 16499948] - Jung Yeop Lee, Surk Sik Moon, Byung Kook Hwang. Isolation and antifungal activity of kakuol, a propiophenone derivative from Asarum sieboldii rhizome.
Pest management science.
2005 Aug; 61(8):821-5. doi:
10.1002/ps.1050. [PMID: 15846774] - Toshihide Suzuki, Hisao Nojiri, Hideo Isono, Takafumi Ochi. Oxidative damages in isolated rat hepatocytes treated with the organochlorine fungicides captan, dichlofluanid and chlorothalonil.
Toxicology.
2004 Nov; 204(2-3):97-107. doi:
10.1016/j.tox.2004.06.025. [PMID: 15388237] - Annemarie P van Wezel, P van Vlaardingen. Environmental risk limits for antifouling substances.
Aquatic toxicology (Amsterdam, Netherlands).
2004 Mar; 66(4):427-44. doi:
10.1016/j.aquatox.2003.11.003. [PMID: 15168950] - A Draper, P Cullinan, C Campbell, M Jones, A Newman Taylor. Occupational asthma from fungicides fluazinam and chlorothalonil.
Occupational and environmental medicine.
2003 Jan; 60(1):76-7. doi:
10.1136/oem.60.1.76. [PMID: 12499462] - Raymond A Putnam, Judd O Nelson, J Marshall Clark. The persistence and degradation of chlorothalonil and chlorpyrifos in a cranberry bog.
Journal of agricultural and food chemistry.
2003 Jan; 51(1):170-6. doi:
10.1021/jf020744r. [PMID: 12502403] - Eric A Rohel, Paul Laurent, Bart A Fraaije, Nadine Cavelier, Derek W Hollomon. Quantitative PCR monitoring of the effect of azoxystrobin treatments on Mycosphaerella graminicola epidemics in the field.
Pest management science.
2002 Mar; 58(3):248-54. doi:
10.1002/ps.431. [PMID: 11975170] - T L Potter, R D Wauchope, A K Culbreath. Accumulation and decay of chlorothalonil and selected metabolites in surface soil following foliar application to peanuts.
Environmental science & technology.
2001 Jul; 35(13):2634-9. doi:
10.1021/es002054e. [PMID: 11452585] - D E Wedge, D G Nagle. A new 2D-TLC bioautography method for the discovery of novel antifungal agents To control plant pathogens.
Journal of natural products.
2000 Aug; 63(8):1050-4. doi:
10.1021/np990628r. [PMID: 10978195] - T Godard, V Fessard, S Huet, A Mourot, E Deslandes, D Pottier, O Hyrien, F Sichel, P Gauduchon, J Poul. Comparative in vitro and in vivo assessment of genotoxic effects of etoposide and chlorothalonil by the comet assay.
Mutation research.
1999 Jul; 444(1):103-16. doi:
10.1016/s1383-5718(99)00100-x. [PMID: 10477344] - A Hillenweck, D E Corpet, J C Killeen, M Bliss, J P Cravedi. Urinary and biliary metabolic patterns of chlorothalonil in germ-free and conventional rats.
Journal of agricultural and food chemistry.
1999 Jul; 47(7):2898-903. doi:
10.1021/jf9811469. [PMID: 10552583] - E Rosner, C Klos, W Dekant. Biotransformation of the fungicide chlorthalonil by glutathione conjugation.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1996 Oct; 33(2):229-34. doi:
10.1006/faat.1996.0160. [PMID: 8921341]