Isosorbide (BioDeep_00000016914)
代谢物信息卡片
Isosorbide
化学式: C6H10O4 (146.057906)
中文名称: 异山梨醇
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(C2C(O1)C(CO2)O)O
InChI: InChI=1S/C6H10O4/c7-3-1-9-6-4(8)2-10-5(3)6/h3-8H,1-2H2/t3-,4+,5-,6-/m1/s1
描述信息
C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent
D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents
D045283 - Natriuretic Agents > D004232 - Diuretics
同义名列表
1 个代谢物同义名
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:6060
- KEGG: C07057
- KEGGdrug: D00347
- PubChem: 12597
- Metlin: METLIN863
- DrugBank: DB09401
- ChEMBL: CHEMBL1200660
- MeSH: Isosorbide
- CAS: 28980-83-8
- CAS: 652-67-5
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- William R Swindell, Krzysztof Bojanowski, Ratan K Chaudhuri. Isosorbide Fatty Acid Diesters Have Synergistic Anti-Inflammatory Effects in Cytokine-Induced Tissue Culture Models of Atopic Dermatitis.
International journal of molecular sciences.
2022 Nov; 23(22):. doi:
10.3390/ijms232214307. [PMID: 36430783] - Sebastian Bonardd, Binoy Maiti, Santiago Grijalvo, Jacqueline Rodríguez, Hamidreza Enshaei, Galder Kortaberria, Carlos Alemán, David Díaz Díaz. Biomass-derived isosorbide-based thermoresponsive hydrogel for drug delivery.
Soft matter.
2022 Jul; 18(26):4963-4972. doi:
10.1039/d2sm00623e. [PMID: 35748523] - Yuki Hiroshima, Keijiro Sato, Toshimitsu Ueki, Masahiko Sumi, Mayumi Ueno, Naoaki Ichikawa, Hidetoshi Satomi, Hikaru Kobayashi. Rapid Improvement in Jaundice Using Transdermal Isosorbide Tape as a Nitric Oxide Donor in Two Adult Patients with Transplantation-associated Microangiopathy Related to Graft-versus-host Disease.
Internal medicine (Tokyo, Japan).
2022 Apr; 61(8):1225-1230. doi:
10.2169/internalmedicine.7789-21. [PMID: 34565772] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Geng Qian, Chang-Fu Liu, Jun Guo, Wei Dong, Jin Wang, Yundai Chen. Prevention of contrast-induced nephropathy by adequate hydration combined with isosorbide dinitrate for patients with renal insufficiency and congestive heart failure.
Clinical cardiology.
2019 Jan; 42(1):21-25. doi:
10.1002/clc.23023. [PMID: 30054906] - S C Steinbach, R Triani, L Bennedsen, A Gabel, O Haeusler, J Wohlrab, R H H Neubert. Retarder action of isosorbide in a microemulsion for a targeted delivery of ceramide NP into the stratum corneum.
Die Pharmazie.
2017 Aug; 72(8):440-446. doi:
10.1691/ph.2017/7004. [PMID: 29441901] - Taizo Takeda, Setsuko Takeda, Natsumi Uehara, Shungaku Yanagisawa, Tatsuya Furukawa, Ken-Ichi Nibu, Akinobu Kakigi. Isosorbide-Induced Decompression Effect on the Scala Media: Participation of Plasma Osmolality and Plasma Arginine Vasopressin.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
2017 04; 38(4):599-605. doi:
10.1097/mao.0000000000001333. [PMID: 28072656] - Muhammad Imran, Humera Shafi, Zahid Mahmood, Mohammad Sarwar, Hafiz Faisal Usman, Mohammad Ashraf Tahir, Muhammad Zar Ashiq. Fatal Intoxications Due to Administration of Isosorbide Tablets Contaminated with Pyrimethamine.
Journal of forensic sciences.
2016 09; 61(5):1382-5. doi:
10.1111/1556-4029.13125. [PMID: 27327266] - Karen J Schimpf, Claudia C Meek, Richard D Leff, Dale L Phelps, Daniel J Schmitz, Christopher T Cordle. Quantification of myo-inositol, 1,5-anhydro- D-sorbitol, and D-chiro-inositol using high-performance liquid chromatography with electrochemical detection in very small volume clinical samples.
Biomedical chromatography : BMC.
2015 Nov; 29(11):1629-36. doi:
10.1002/bmc.3470. [PMID: 26010453] - Xiaoli Wang, Linna Wang, Tingting Li, Zhangjian Huang, Yisheng Lai, Hui Ji, Xiaolong Wan, Jinyi Xu, Jide Tian, Yihua Zhang. Novel hybrids of optically active ring-opened 3-n-butylphthalide derivative and isosorbide as potential anti-ischemic stroke agents.
Journal of medicinal chemistry.
2013 Apr; 56(7):3078-89. doi:
10.1021/jm4001693. [PMID: 23509954] - Neal T Wasserman, Gavin Kennard, Zachary N Cochrane, Lisa M Felchle. Effects of oral isosorbide and glycerol on intraocular pressure, serum osmolality, and blood glucose in normal dogs.
Veterinary ophthalmology.
2013 Jan; 16(1):20-4. doi:
10.1111/j.1463-5224.2012.01011.x. [PMID: 22512809] - Mark T Ledwidge, Fiona Ryan, David M Kerins, Damian O'Connell, Gene Cefali, Shona Harmon, Michael Jones, John F Gilmer. In vivo impact of prodrug isosorbide-5-nicotinate-2-aspirinate on lipids and prostaglandin D2: is this a new immediate-release therapeutic option for niacin?.
Atherosclerosis.
2012 Apr; 221(2):478-83. doi:
10.1016/j.atherosclerosis.2012.01.016. [PMID: 22326030] - José Sereno, Ana M Romão, Belmiro Parada, Patrícia Lopes, Eugénia Carvalho, Frederico Teixeira, Flávio Reis. Cardiorenal benefits of early versus late cyclosporine to sirolimus conversion in a rat model.
Journal of pharmacology & pharmacotherapeutics.
2012 Apr; 3(2):143-8. doi:
10.4103/0976-500x.95513. [PMID: 22629089] - Kazunari Okada, Shin-ichi Ishimoto, Yoko Fujimaki, Tatsuya Yamasoba. Trial of Chinese medicine Wu-Ling-San for acute low-tone hearing loss.
ORL; journal for oto-rhino-laryngology and its related specialties.
2012; 74(3):158-63. doi:
10.1159/000337819. [PMID: 22584914] - Kovanya Moodley, Viness Pillay, Yahya E Choonara, Lisa C du Toit, Valence M K Ndesendo, Pradeep Kumar, Shivaan Cooppan, Priya Bawa. Oral drug delivery systems comprising altered geometric configurations for controlled drug delivery.
International journal of molecular sciences.
2012; 13(1):18-43. doi:
10.3390/ijms13010018. [PMID: 22312236] - Clara Sciorati, Daniela Miglietta, Roberta Buono, Viviana Pisa, Dario Cattaneo, Emanuele Azzoni, Silvia Brunelli, Emilio Clementi. A dual acting compound releasing nitric oxide (NO) and ibuprofen, NCX 320, shows significant therapeutic effects in a mouse model of muscular dystrophy.
Pharmacological research.
2011 Sep; 64(3):210-7. doi:
10.1016/j.phrs.2011.05.003. [PMID: 21609764] - Ren Guo, Lei Chen, Ling Li, Xin Guo, Ji Sun, Xiao-Ming Xiong, Ze-Neng Cheng, Yuan-Jian Li, Xiao-Ping Chen. Association of GSTM1 null polymorphism with isosorbide-5-mononitrate cardiovascular response and involvement of CGRP in healthy Chinese male volunteers.
Pharmacogenetics and genomics.
2011 Mar; 21(3):142-51. doi:
10.1097/fpc.0b013e328343ea0a. [PMID: 21278620] - Guilherme Veiga Guimarães, Veridiana D'Avila, Edimar Alcides Bocchi, Vitor Oliveira Carvalho. Norepinephrine remains increased in the six-minute walking test after heart transplantation.
Clinics (Sao Paulo, Brazil).
2010 Jun; 65(6):587-91. doi:
10.1590/s1807-59322010000600005. [PMID: 20613934] - Stéphane Guillarme, Jean-Bernard Behr, Claudia Bello, Pierre Vogel, Christine Saluzzo. Synthesis and glycosidase inhibitory activity of 1-amino-3,6-anhydro-1-deoxy-D-sorbitol derivatives.
Bioorganic chemistry.
2010 Apr; 38(2):43-7. doi:
10.1016/j.bioorg.2009.12.002. [PMID: 20060997] - Gerald P Dillon, Joanne M Gaynor, Denise Khan, Ciaran G Carolan, Sheila A Ryder, Juan F Marquez, Sean Reidy, John F Gilmer. Isosorbide-based cholinesterase inhibitors; replacement of 5-ester groups leading to increased stability.
Bioorganic & medicinal chemistry.
2010 Feb; 18(3):1045-53. doi:
10.1016/j.bmc.2009.12.052. [PMID: 20093035] - Liliana Ferreira, Edite Teixeira-de-Lemos, Filipa Pinto, Belmiro Parada, Cristina Mega, Helena Vala, Rui Pinto, Patrícia Garrido, José Sereno, Rosa Fernandes, Paulo Santos, Isabel Velada, Andreia Melo, Sara Nunes, Frederico Teixeira, Flávio Reis. Effects of sitagliptin treatment on dysmetabolism, inflammation, and oxidative stress in an animal model of type 2 diabetes (ZDF rat).
Mediators of inflammation.
2010; 2010(?):592760. doi:
10.1155/2010/592760. [PMID: 20652060] - Michael Jones, Iwona Inkielewicz, Carlos Medina, Maria Jose Santos-Martinez, Anna Radomski, Marek W Radomski, Maeve N Lally, Louise M Moriarty, Joanne Gaynor, Ciaran G Carolan, Denise Khan, Paul O'Byrne, Shona Harmon, Valerie Holland, John M Clancy, John F Gilmer. Isosorbide-based aspirin prodrugs: integration of nitric oxide releasing groups.
Journal of medicinal chemistry.
2009 Nov; 52(21):6588-98. doi:
10.1021/jm900561s. [PMID: 19821574] - Tsung-Ming Lee, Nen-Chung Chang. Effect of nicorandil on proteinuria in well controlled hypertensive patients.
Journal of hypertension.
2009 Mar; 27(3):618-25. doi:
10.1097/hjh.0b013e32831cbd73. [PMID: 19262229] - Louise M Moriarty, Maeve N Lally, Ciaran G Carolan, Michael Jones, John M Clancy, John F Gilmer. Discovery of a 'true' aspirin prodrug.
Journal of medicinal chemistry.
2008 Dec; 51(24):7991-9. doi:
10.1021/jm801094c. [PMID: 19049433] - Ciaran G Carolan, Gerald P Dillon, Joanne M Gaynor, Sean Reidy, Sheila A Ryder, Denise Khan, Juan F Marquez, John F Gilmer. Isosorbide-2-carbamate esters: potent and selective butyrylcholinesterase inhibitors.
Journal of medicinal chemistry.
2008 Oct; 51(20):6400-9. doi:
10.1021/jm800564y. [PMID: 18817366] - D Khan, J F Gilmer, C G Carolan, J M Gaynor, S A Ryder. Pharmacological effects of a novel isosorbide-based butyrylcholinesterase inhibitor.
Chemico-biological interactions.
2008 Sep; 175(1-3):231-4. doi:
10.1016/j.cbi.2008.05.024. [PMID: 18606399] - José Mario Barichello, Noriko Yamakawa, Masatoshi Kisyuku, Hiroshi Handa, Taiki Shibata, Tatsuhiro Ishida, Hiroshi Kiwada. Combined effect of liposomalization and addition of glycerol on the transdermal delivery of isosorbide 5-nitrate in rat skin.
International journal of pharmaceutics.
2008 Jun; 357(1-2):199-205. doi:
10.1016/j.ijpharm.2008.01.052. [PMID: 18343610] - Yiu-fai Cheung, Karmin O, Connie W H Woo, Stephanie Armstrong, Yaw L Siow, Pak-cheong Chow, Eddie W Y Cheung. Oxidative stress in children late after Kawasaki disease: relationship with carotid atherosclerosis and stiffness.
BMC pediatrics.
2008 May; 8(?):20. doi:
10.1186/1471-2431-8-20. [PMID: 18466622] - Yuta Saito, Pete Geisen, Abhineet Uppal, M Elizabeth Hartnett. Inhibition of NAD(P)H oxidase reduces apoptosis and avascular retina in an animal model of retinopathy of prematurity.
Molecular vision.
2007 Jun; 13(?):840-53. doi:
". [PMID: 17615545] - Xiaohong Sun, Xiaoqin Li, Shuang Cai, Feng Qin, Xiumei Lu, Famei Li. High performance liquid chromatography-electrospray ionization mass spectrometric determination of isosorbide 5-mononitrate in human plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2007 Feb; 846(1-2):323-8. doi:
10.1016/j.jchromb.2006.08.022. [PMID: 16962389] - Jeff C Huffman, Theodore A Stern. Neuropsychiatric consequences of cardiovascular medications.
Dialogues in clinical neuroscience.
2007; 9(1):29-45. doi:
. [PMID: 17506224] - Lara C Silva, Lina S O B Oliveira, Gustavo D Mendes, Gabriel Garcia, Alberto Dos Santos Pereira, Gilberto De Nucci. Quantification of isosorbide 5-mononitrate in human plasma by liquid chromatography-tandem mass spectrometry using atmospheric pressure photoionization.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2006 Mar; 832(2):302-6. doi:
10.1016/j.jchromb.2005.12.027. [PMID: 16464650] - Dogan Erdogan, Hakan Gullu, Erkan Yildirim, Derya Tok, Ismail Kirbas, Ozgur Ciftci, Semra Topcu Baycan, Haldun Muderrisoglu. Low serum bilirubin levels are independently and inversely related to impaired flow-mediated vasodilation and increased carotid intima-media thickness in both men and women.
Atherosclerosis.
2006 Feb; 184(2):431-7. doi:
10.1016/j.atherosclerosis.2005.05.011. [PMID: 15979081] - Akinobu Kakigi, Taizo Takeda, Shoichi Sawada, Daizo Taguchi. Antidiuretic hormone and osmolality in isosorbide therapy and glycerol test.
ORL; journal for oto-rhino-laryngology and its related specialties.
2006; 68(5):279-82. doi:
10.1159/000093299. [PMID: 16699291] - J F Gilmer, M N Lally, P Gardiner, G Dillon, J M Gaynor, S Reidy. Novel isosorbide-based substrates for human butyrylcholinesterase.
Chemico-biological interactions.
2005 Dec; 157-158(?):317-9. doi:
10.1016/j.cbi.2005.10.095. [PMID: 16266694] - Joanne M Gaynor, Gerald P Dillon, Sean Reidy, John F Gilmer. Synthesis and structure activity relationships (SAR) of a new class of potent and selective butyrylcholinesterase inhibitors.
Chemico-biological interactions.
2005 Dec; 157-158(?):380-1. doi:
10.1016/j.cbi.2005.10.063. [PMID: 16429505] - Flávio Reis, Luís Rocha, Luísa Ponte, Teresa Alcobia, Luís Almeida, Carlos Costa-Almeida, Frederico Teixeira. Effect of preventive and regressive isosorbide 5-mononitrate treatment on catecholamine levels in plasma, platelets, adrenals, left ventricle and aorta in cyclosporin A-induced hypertensive rats.
Life sciences.
2005 Sep; 77(20):2514-28. doi:
10.1016/j.lfs.2005.01.032. [PMID: 15953621] - Maria Kopff, Edward Kowalczyk, Anna Kopff. [Nitric oxide and cardiologic drugs].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego.
2005 May; 18(107):521-3. doi:
NULL. [PMID: 16161946] - Nina Grosser, Henning Schröder. [Therapy with NO donors-antiatherogenic and antioxidant actions].
Herz.
2004 Feb; 29(1):116-22. doi:
10.1007/s00059-004-2530-3. [PMID: 14968347] - Jun Chen, Xin Guo Jiang, Lei Cai, Wei Lu, Ke Pan Gao, Zheng Qi Shi, Qi Zhiang Zhang. Pharmacokinetics of three organic nitrates in Chinese healthy male volunteers.
Arzneimittel-Forschung.
2004; 54(4):203-6. doi:
10.1055/s-0031-1296960. [PMID: 15146932] - Srinivas Nammi, Rambabu Gudavalli, Behara S Ravindra Babu, Durga S Lodagala, Krishna M Boini. Possible mechanisms of hypotension produced 70\% alcoholic extract of Terminalia arjuna (L.) in anaesthetized dogs.
BMC complementary and alternative medicine.
2003 Oct; 3(?):5. doi:
10.1186/1472-6882-3-5. [PMID: 14561229] - John F Gilmer, Michael A Murphy, Jean A Shannon, Colm G Breen, Sheila A Ryder, John M Clancy. Single oral dose study of two isosorbide-based aspirin prodrugs in the dog.
The Journal of pharmacy and pharmacology.
2003 Oct; 55(10):1351-7. doi:
10.1211/0022357022007. [PMID: 14607016] - Chikara Goto, Yukihito Higashi, Masashi Kimura, Kensuke Noma, Keiko Hara, Keigo Nakagawa, Mitsutoshi Kawamura, Kazuaki Chayama, Masao Yoshizumi, Isao Nara. Effect of different intensities of exercise on endothelium-dependent vasodilation in humans: role of endothelium-dependent nitric oxide and oxidative stress.
Circulation.
2003 Aug; 108(5):530-5. doi:
10.1161/01.cir.0000080893.55729.28. [PMID: 12874192] - Mikio Kakumoto, Kohji Takara, Toshiyuki Sakaeda, Yusuke Tanigawara, Tomoko Kita, Katsuhiko Okumura. MDR1-mediated interaction of digoxin with antiarrhythmic or antianginal drugs.
Biological & pharmaceutical bulletin.
2002 Dec; 25(12):1604-7. doi:
10.1248/bpb.25.1604. [PMID: 12499648] - John F Gilmer, Louise M Moriarty, Maeve N Lally, John M Clancy. Isosorbide-based aspirin prodrugs. II. Hydrolysis kinetics of isosorbide diaspirinate.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2002 Sep; 16(4-5):297-304. doi:
10.1016/s0928-0987(02)00124-0. [PMID: 12208460] - Adrian P Funke, Roman Schiller, Hans W Motzkus, Clemens Günther, Rainer H Müller, Ralph Lipp. Transdermal delivery of highly lipophilic drugs: in vitro fluxes of antiestrogens, permeation enhancers, and solvents from liquid formulations.
Pharmaceutical research.
2002 May; 19(5):661-8. doi:
10.1023/a:1015314314796. [PMID: 12069170] - M T Osinski, B H Rauch, K Schrör. Antimitogenic actions of organic nitrates are potentiated by sildenafil and mediated via activation of protein kinase A.
Molecular pharmacology.
2001 May; 59(5):1044-50. doi:
10.1124/mol.59.5.1044. [PMID: 11306686] - I Niopas, A C Daftsios, N Nikolaidis. Relative bioavailability of two isosorbide dinitrate sublingual tablet formulations administered as single doses in healthy subjects.
International journal of clinical pharmacology and therapeutics.
2001 May; 39(5):224-8. doi:
10.5414/cpp39224. [PMID: 11380069] - J Bolanowski, M Kobusiak-Prokopowicz, B Wegrzyn. [Interactions between propranolol, isosorbide and nitroglycerin].
Polski tygodnik lekarski (Warsaw, Poland : 1960).
1992 Dec; 47(51-52):1141-2. doi:
NULL. [PMID: 1307104] - P O Edlund, K Johansen. Clean-up of plasma extracts by gel permeation chromatography during analysis of isosorbide nitrates by capillary gas chromatography.
Journal of chromatography.
1991 Aug; 553(1-2):21-7. doi:
10.1016/s0021-9673(01)88467-3. [PMID: 1787155] - M Vejar, G Fragasso, D Hackett, D P Lipkin, A Maseri, G V Born, G Ciabattoni, C Patrono. Dissociation of platelet activation and spontaneous myocardial ischemia in unstable angina.
Thrombosis and haemostasis.
1990 Apr; 63(2):163-8. doi:
. [PMID: 2363117] - J Bechler-Lisińska, M Cholewa, L Górski, K Markiewicz. [Effect of vasodilator agents on the character and incidence of cardiac arrhythmia in chronic heart failure].
Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete.
1990 Mar; 45(3):71-6. doi:
NULL. [PMID: 2186579] - H Kitano, M Kitahara. Serum osmolality in Menière's disease.
The American journal of otology.
1987 Jul; 8(4):327-9. doi:
NULL. [PMID: 3631241] - F P Berenger, J P Cano, P H Rolland. Antithrombogenic endothelial cell defense. Basal characteristics in cultured endothelial cells and modulation by short-term and long-term exposure to isosorbide nitrates.
Circulation research.
1987 Apr; 60(4):612-20. doi:
10.1161/01.res.60.4.612. [PMID: 3594743] - ". Acute myocardial infarction treated with yiqihuoxue mixture. A comparative study of therapeutic effects on 430 patients.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
1986 Sep; 6(3):165-7. doi:
". [PMID: 3807409] - W C Elliott, D C Houghton, D N Gilbert, J Baines-Hunter, W M Bennett. Experimental gentamicin nephrotoxicity: effect of streptozotocin-induced diabetes.
The Journal of pharmacology and experimental therapeutics.
1985 Apr; 233(1):264-70. doi:
NULL. [PMID: 3156984] - S G Wood, B A John, L F Chasseaud, R M Major, M E Forrest, R Bonn, A Darragh, R F Lambe. Metabolic fact of 14C-isosorbide 5-mononitrate in humans.
Arzneimittel-Forschung.
1984; 34(9):1031-5. doi:
NULL. [PMID: 6542370] - A Sioufi, F Pommier. Determination of isosorbide as a metabolite of isosorbide dinitrate in human urine by capillary gas chromatography with electron-capture detection.
Journal of chromatography.
1983 Oct; 277(?):157-64. doi:
10.1016/s0378-4347(00)84832-x. [PMID: 6643601] - J Maddock, P A Lewis, A Woodward, P R Massey, S Kennedy. Determination of isosorbide dinitrate and its mononitrate metabolites in human plasma by high-performance liquid chromatography-thermal energy analysis.
Journal of chromatography.
1983 Jan; 272(1):129-36. doi:
10.1016/s0378-4347(00)86109-5. [PMID: 6841532] - R A Newman, L B Weinstock, D W Gump, M P Hacker, J W Yates. Effect of osmotic diuresis on gentamicin-induced nephrotoxicity in rats.
Archives of toxicology.
1980 Sep; 45(3):213-21. doi:
10.1007/bf02419001. [PMID: 7458670] - R A Newman, A R Brody, I H Krakoff. Gallium nitrate (NSC-15200) induced toxicity in the rat: a pharmacologic, histopathologic and microanalytical investigation.
Cancer.
1979 Nov; 44(5):1728-40. doi:
10.1002/1097-0142(197911)44:5<1728::aid-cncr2820440529>3.0.co;2-s. [PMID: 498044] - M T Rosseel, M G Bogaert. Simultaneous determination of isosorbide dinitrate and its mononitrates in human plasma by capillary column GLC.
Journal of pharmaceutical sciences.
1979 May; 68(5):659-60. doi:
10.1002/jps.2600680542. [PMID: 430513] - L Richard, G Klein, J M Orr. Simultaneous measurement of plasma isosorbide dinitrate, isosorbide-2-mononitrate, and isosorbide-5-mononitrate by gas-liquid chromatography.
Clinical chemistry.
1976 Dec; 22(12):2060-1. doi:
10.1093/clinchem/22.12.2060. [PMID: 1000812] - W Aoi, D P Henry, M H Weinberger. Evidence for a physiological role of renal sympathetic nerves in adrenergic stimulation of renin release in the rat.
Circulation research.
1976 Feb; 38(2):UNKNOWN. doi:
. [PMID: 1155] - J Lorber. Isosorbide in treatment of infantile hydrocephalus.
Archives of disease in childhood.
1975 Jun; 50(6):431-6. doi:
10.1136/adc.50.6.431. [PMID: 1096833] - J F TREON, L E GONGWER, W H RUEGGEBERG. ISOSORBIDE, A NEW ORAL OSMOTIC DIURETIC.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1965 May; 119(?):39-42. doi:
10.3181/00379727-119-30092. [PMID: 14297877]