5-Hydroxyectoine (BioDeep_00000016698)

   


代谢物信息卡片


(4S,5S)-5-Hydroxy-2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid

化学式: C6H10N2O3 (158.0691)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(otcml) 42.29%

分子结构信息

SMILES: CC1=NCC(C(N1)C(=O)O)O
InChI: InChI=1S/C6H10N2O3/c1-3-7-2-4(9)5(8-3)6(10)11/h4-5,9H,2H2,1H3,(H,7,8)(H,10,11)/t4-,5-/m0/s1

描述信息

同义名列表

28 个代谢物同义名

(4S,5S)-5-Hydroxy-2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid; 5-Hydroxyectoine; .BETA.-HYDROXYECTOINE; (4S,5S)-2-methyl-4-carboxy-5-hydroxy-3,4,5,6-tetrahydropyrimidine; (4S,5S)-5-Hydroxy-2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid;THP(A);Hydroxyectoin; Hydroxy ection; Hydroxy ectoine; (4S,5S)-5-Hydroxy-2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylicacid; (5S,6S)-5-hydroxy-2-methyl-1,4,5,6-tetrahydropyrimidine-6-carboxylic acid; (S,S)--Hydroxyectoine; 5-Hydroxyectoine; Pyrostatin A; Pyrostatine A; -Hydroxyectoine; (S,S)-.BETA.-HYDROXYECTOINE; (S,S)-1,4,5,6-Tetrahydro-5-hydroxy-2-methyl-4-pyrimidinecarboxylic acid; (S,S)-2-methyl-5-hydroxy-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid; (S,S)-beta-Hydroxyectoine; 4-hydroxy-imino-1-methylpyrrolidone-5-carboxylic acid; 4-pyrimidinecarboxylic acid, 1,4,5,6-tetrahydro-5-hydroxy-2-methyl-, (4S,5S)-; 4-Pyrimidinecarboxylic acid, 1,4,5,6-tetrahydro-5-hydroxy-2-methyl-, (S-(R*,R*))-; 4-Pyrimidinecarboxylicacid,1,4,5,6-tetrahydro-5-hydroxy-2-methyl-,(4S,5S)-; 6CS; beta-hydroxyectoine; CIJ7YN252E; Hydroxyectoin; HYDROXYECTOIN [INCI]; hydroxyectoine; Hydroxyectoine, >=95% (HPLC); Hydroxyectoine, primary pharmaceutical reference standard; KIIBBJKLKFTNQO-WHFBIAKZSA-N; Pyrostatin A; Ronacare hydroxyectoin; UNII-CIJ7YN252E



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Raphael Ledermann, Barbara Emmenegger, Jean-Malo Couzigou, Nicola Zamboni, Patrick Kiefer, Julia A Vorholt, Hans-Martin Fischer. Bradyrhizobium diazoefficiens Requires Chemical Chaperones To Cope with Osmotic Stress during Soybean Infection. mBio. 2021 03; 12(2):. doi: 10.1128/mbio.00390-21. [PMID: 33785618]
  • D V Yanykin, M Malferrari, S Rapino, G Venturoli, A Yu Semenov, M D Mamedov. Hydroxyectoine protects Mn-depleted photosystem II against photoinhibition acting as a source of electrons. Photosynthesis research. 2019 Aug; 141(2):165-179. doi: 10.1007/s11120-019-00617-w. [PMID: 30701483]
  • Poulami Chatterjee, Sandipan Samaddar, Ülo Niinemets, Tong-Min Sa. Brevibacterium linens RS16 confers salt tolerance to Oryza sativa genotypes by regulating antioxidant defense and H+ ATPase activity. Microbiological research. 2018 Oct; 215(?):89-101. doi: 10.1016/j.micres.2018.06.007. [PMID: 30172313]
  • Laura Czech, Sebastian Poehl, Philipp Hub, Nadine Stöveken, Erhard Bremer. Tinkering with Osmotically Controlled Transcription Allows Enhanced Production and Excretion of Ectoine and Hydroxyectoine from a Microbial Cell Factory. Applied and environmental microbiology. 2018 01; 84(2):. doi: 10.1128/aem.01772-17. [PMID: 29101191]
  • ZhiHui Shao, WanXin Deng, ShiYuan Li, JuanMei He, ShuangXi Ren, WeiRen Huang, YinHua Lu, GuoPing Zhao, ZhiMing Cai, Jin Wang. GlnR-Mediated Regulation of ectABCD Transcription Expands the Role of the GlnR Regulon to Osmotic Stress Management. Journal of bacteriology. 2015 Oct; 197(19):3041-7. doi: 10.1128/jb.00185-15. [PMID: 26170409]
  • Pramod Kadaba Srinivasan, Ngwi Fet, Christian Bleilevens, Mamdouh Afify, Benedict Doorschodt, Shintaro Yagi, Gerhild van Echten-Deckert, René Hany Tolba. Hydroxyectoine ameliorates preservation injury in deceased after cardiac death donors in experimental liver grafts. Annals of transplantation. 2014 Apr; 19(?):165-73. doi: 10.12659/aot.889958. [PMID: 24727658]
  • Jens Smiatek, Rakesh Kumar Harishchandra, Hans-Joachim Galla, Andreas Heuer. Low concentrated hydroxyectoine solutions in presence of DPPC lipid bilayers: a computer simulation study. Biophysical chemistry. 2013 Oct; 180-181(?):102-9. doi: 10.1016/j.bpc.2013.07.001. [PMID: 23911954]
  • Rakesh Kumar Harishchandra, Amit Kumar Sachan, Andreas Kerth, Georg Lentzen, Thorsten Neuhaus, Hans-Joachim Galla. Compatible solutes: ectoine and hydroxyectoine improve functional nanostructures in artificial lung surfactants. Biochimica et biophysica acta. 2011 Dec; 1808(12):2830-40. doi: 10.1016/j.bbamem.2011.08.022. [PMID: 21889490]
  • Rakesh Kumar Harishchandra, Stephanie Wulff, Georg Lentzen, Thorsten Neuhaus, Hans-Joachim Galla. The effect of compatible solute ectoines on the structural organization of lipid monolayer and bilayer membranes. Biophysical chemistry. 2010 Aug; 150(1-3):37-46. doi: 10.1016/j.bpc.2010.02.007. [PMID: 20206435]
  • Daniel Appel, Georg Lentzen. The pyrostatins A and B do not inhibit N-acetyl-beta-D-glucosaminidase. Journal of enzyme inhibition and medicinal chemistry. 2009 Oct; 24(5):1106-8. doi: 10.1080/14756360802632831. [PMID: 19555187]
  • Sandra Cornacchione, Neil S Sadick, Michele Neveu, Sylvie Talbourdet, Kristell Lazou, Cecile Viron, Isabelle Renimel, Delphine de Quéral, Robin Kurfurst, Sylvianne Schnebert, Catherine Heusèle, Patrice André, Eric Perrier. In vivo skin antioxidant effect of a new combination based on a specific Vitis vinifera shoot extract and a biotechnological extract. Journal of drugs in dermatology : JDD. 2007 Jun; 6(6 Suppl):s8-13. doi: NULL. [PMID: 17691204]