risperidone (BioDeep_00000016609)

   


代谢物信息卡片


risperidone

化学式: C23H27FN4O2 (410.2117934)
中文名称: 利哌酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F
InChI: InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3

描述信息

D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents
D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants
C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent
N - Nervous system > N05 - Psycholeptics > N05A - Antipsychotics
CONFIDENCE standard compound; INTERNAL_ID 1505
CONFIDENCE standard compound; INTERNAL_ID 8513
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3353
Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.

同义名列表

2 个代谢物同义名

risperidone; R 64 766



数据库引用编号

39 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Si-Yu Zhai, Hong-Wei Gu, Cong Wang, Yu-Sang Li, He-Bin Tang. Gynura procumbens and selected metabolites: Amelioration of depressive-like behaviors in mice and risperidone-induced hyperprolactinemia in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 Apr; 173(?):116361. doi: 10.1016/j.biopha.2024.116361. [PMID: 38428310]
  • Yuying Chen, Qingwei He, Huangjie Lu, Jie Yang, Jiongming Han, Ying Zhu, Ping Hu. Visualization and correlation of drug release of risperidone/clozapine microspheres in vitro and in vivo based on FRET mechanism. International journal of pharmaceutics. 2024 Mar; 653(?):123885. doi: 10.1016/j.ijpharm.2024.123885. [PMID: 38325621]
  • Marco Pozzi, Chiara Vantaggiato, Francesca Brivio, Genny Orso, Maria Teresa Bassi. Olanzapine, risperidone and ziprasidone differently affect lysosomal function and autophagy, reflecting their different metabolic risk in patients. Translational psychiatry. 2024 Jan; 14(1):13. doi: 10.1038/s41398-023-02686-x. [PMID: 38191558]
  • Sergej Nadalin, Lena Zatković, Vjekoslav Peitl, Dalibor Karlović, Maja Vilibić, Ante Silić, Sanja Dević Pavlić, Alena Buretić-Tomljanović. An association between PPARα-L162V polymorphism and increased plasma LDL cholesterol levels after risperidone treatment. Prostaglandins, leukotrienes, and essential fatty acids. 2024 Jan; 200(?):102604. doi: 10.1016/j.plefa.2023.102604. [PMID: 38113727]
  • Loretta Hsueh, Esti Iturralde, Natalie E Slama, Scott R Spalding, Stacy A Sterling. Cardiometabolic Monitoring and Sociodemographic and Clinical Characteristics of Youths Prescribed Antipsychotic Medications. Psychiatric services (Washington, D.C.). 2023 08; 74(8):801-808. doi: 10.1176/appi.ps.20220151. [PMID: 37016828]
  • Zhe Lu, Yuyanan Zhang, Yaoyao Sun, Yundan Liao, Zhewei Kang, Xiaoyang Feng, Hao Yan, Lifang Wang, Tianlan Lu, Dai Zhang, Weihua Yue. Therapeutic Outcomes Wide Association Scan of different antipsychotics in patients with schizophrenia: randomized clinical trials and multi-ancestry validation. Psychiatry and clinical neurosciences. 2023 May; ?(?):. doi: 10.1111/pcn.13567. [PMID: 37210704]
  • Javier Vázquez-Bourgon, Víctor Ortiz-García de la Foz, Marcos Gómez-Revuelta, Jacqueline Mayoral-van Son, María Juncal-Ruiz, Nathalia Garrido-Torres, Benedicto Crespo-Facorro. Aripiprazole and Risperidone Present Comparable Long-Term Metabolic Profiles: Data From a Pragmatic Randomized Controlled Trial in Drug-Naïve First-Episode Psychosis. The international journal of neuropsychopharmacology. 2022 10; 25(10):795-806. doi: 10.1093/ijnp/pyac033. [PMID: 35641112]
  • Reeha Sharon, Theis Lange, Mia Aakjær, Sarah Brøgger Kristiansen, Morten Baltzer Houlind, Morten Andersen. Incidence of hospital contacts with acute kidney injury after initiation of second-generation antipsychotics in older adults: a Danish population-based cohort study. European journal of clinical pharmacology. 2022 Aug; 78(8):1341-1349. doi: 10.1007/s00228-022-03339-6. [PMID: 35639132]
  • Mohamed Ismail, Thomas Straubinger, Hiroyuki Uchida, Ariel Graff-Guerrero, Shinichiro Nakajima, Takefumi Suzuki, Fernando Caravaggio, Philip Gerretsen, David Mamo, Benoit H Mulsant, Bruce G Pollock, Robert Bies. MAP Bayesian modelling combining striatal dopamine receptor occupancy and plasma concentrations to optimize antipsychotic dose regimens in individual patients. British journal of clinical pharmacology. 2022 07; 88(7):3341-3350. doi: 10.1111/bcp.15260. [PMID: 35112390]
  • Bahareh Sadat Yousefsani, Ahmad Salimi, Farnaz Imani, Maral Ramezani, Kobra Shirani, Enayatollah Seydi, Jalal Pourahmad. Risperidone Toxicity on Human Blood Lymphocytes in Nano molar Concentrations. Drug research. 2022 Jul; 72(6):343-349. doi: 10.1055/a-1830-8701. [PMID: 35605969]
  • Theocharis Chr Kyziridis. [Clinical pharmacokinetics and pharmaceutical forms of long-acting injectable antipsychotics]. Psychiatrike = Psychiatriki. 2022 Jun; 33(2):139-148. doi: 10.22365/jpsych.2021.035. [PMID: 34390562]
  • R Taurines, S Fekete, A Preuss-Wiedenhoff, A Warnke, C Wewetzer, P Plener, R Burger, M Gerlach, M Romanos, K M Egberts. Therapeutic drug monitoring in children and adolescents with schizophrenia and other psychotic disorders using risperidone. Journal of neural transmission (Vienna, Austria : 1996). 2022 06; 129(5-6):689-701. doi: 10.1007/s00702-022-02485-6. [PMID: 35303169]
  • Jose de Leon. Precision psychiatry: The complexity of personalizing antipsychotic dosing. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 2022 05; 58(?):80-85. doi: 10.1016/j.euroneuro.2022.03.001. [PMID: 35314415]
  • Seyedeh Nesa Rezaeian Shiadeh, Elham Khodaverdi, Mahdi Faal Maleki, Farhad Eisvand, Hamidreza Boujaran, Hassan Zarei, Ramin Vosooghi, Farzin Hadizadeh, Hossein Kamali. Lipid-liquid crystals for 2 months controlled risperidone release: In-vitro evaluation and pharmacokinetics in rabbits. International journal of pharmaceutics. 2022 Apr; 618(?):121649. doi: 10.1016/j.ijpharm.2022.121649. [PMID: 35278600]
  • Jaymin C Shah, Jinyang Hong. Model for Long Acting Injectables (Depot Formulation) Based on Pharmacokinetics and Physical Chemical Properties. The AAPS journal. 2022 03; 24(3):44. doi: 10.1208/s12248-022-00695-0. [PMID: 35298711]
  • Cintia R Prokopez, Romina Farinola, Miguel Vallejos, Lorena S Lopredo, Luciano E Sfriso, Luciana C Chiapella, Claudio Arce, Ricardo M Corral, Manuel J Cuesta, Martín Alomo. Olanzapine, risperidone and quetiapine: Do these atypical antipsychotics have a protective effect for SARS-CoV-2?. Schizophrenia research. 2022 03; 241(?):140-141. doi: 10.1016/j.schres.2022.01.035. [PMID: 35123336]
  • Alberto Trinchieri, Gianpaolo Perletti, Vittorio Magri, Konstantinos Stamatiou, Margherita Trinchieri, Emanuele Montanari. Drug-induced gynecomastia: A systematic review and meta-analysis of randomized clinical trials. Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica. 2021 Dec; 93(4):489-496. doi: 10.4081/aiua.2021.4.489. [PMID: 34933535]
  • Yan Zhang, Han Shi, Ge Yang, Yongfeng Yang, Wenqiang Li, Meng Song, Minglong Shao, Xi Su, Luxian Lv. Associations between expression of indoleamine 2, 3-dioxygenase enzyme and inflammatory cytokines in patients with first-episode drug-naive Schizophrenia. Translational psychiatry. 2021 11; 11(1):595. doi: 10.1038/s41398-021-01688-x. [PMID: 34802039]
  • Noa Katz Shroitman, Einat Peles, Sharona Even-Tov, Shaul Schreiber, Oren Tene. False-positive fentanyl screening kit results during treatment with long term injectable risperidone (Risperdal-Consta). Psychiatry research. 2021 11; 305(?):114246. doi: 10.1016/j.psychres.2021.114246. [PMID: 34717208]
  • Weijie Yi, Emma Sylvester, Jiamei Lian, Chao Deng. Kidney plays an important role in ketogenesis induced by risperidone and voluntary exercise in juvenile female rats. Psychiatry research. 2021 11; 305(?):114196. doi: 10.1016/j.psychres.2021.114196. [PMID: 34488011]
  • Minami Tasaki, Norio Yasui-Furukori, Saaya Yokoyama, Masataka Shinozaki, Norio Sugawara, Kazutaka Shimoda. Hypoprolactinemia and hyperprolactinemia in male schizophrenia patients treated with aripiprazole and risperidone and their relationships with testosterone levels. Neuropsychopharmacology reports. 2021 09; 41(3):379-384. doi: 10.1002/npr2.12190. [PMID: 34189861]
  • D Boels, J Mahé, A Olry, A Citterio-Quentin, J Moragny, P Jolliet. Fatal and life-threatening ADRs associated with paliperidone palmitate: an observational study in the French pharmacovigilance database. Clinical toxicology (Philadelphia, Pa.). 2021 Sep; 59(9):786-793. doi: 10.1080/15563650.2021.1878206. [PMID: 33555955]
  • Yuan-Yuan Zhang, Xie-Hai Zhou, Feng Shan, Jun Liang. Infection is associated with elevated serum concentrations of antipsychotic drugs. International clinical psychopharmacology. 2021 09; 36(5):264-267. doi: 10.1097/yic.0000000000000366. [PMID: 34030168]
  • Mariane Nunes Noto, Michael Maes, Sandra Odebrecht Vargas Nunes, Vanessa Kiyomi Ota, Daniel Cavalcante, Giovany Oliveira, Ana C Rossaneis, Waldiceu A Verri, Quirino Cordeiro, Sintia Iole Belangero, Ary Gadelha, Cristiano Noto, Rodrigo Affonseca Bressan. BDNF in antipsychotic naive first episode psychosis: Effects of risperidone and the immune-inflammatory response system. Journal of psychiatric research. 2021 09; 141(?):206-213. doi: 10.1016/j.jpsychires.2021.07.011. [PMID: 34246975]
  • Jesper Østrup Rasmussen, Poul Jennum, Kristian Linnet, Birte Y Glenthøj, Lone Baandrup. Cannabidiol versus risperidone for treatment of recent-onset psychosis with comorbid cannabis use: study protocol for a randomized controlled clinical trial. BMC psychiatry. 2021 08; 21(1):404. doi: 10.1186/s12888-021-03395-9. [PMID: 34391393]
  • Sonia Alavi, Mohammad A Mahjoob, Azadeh Haeri, Farshad H Shirazi, Zahra Abbasian, Simin Dadashzadeh. Multivesicular liposomal depot system for sustained delivery of risperidone: development, characterization, and toxicity assessment. Drug development and industrial pharmacy. 2021 Aug; 47(8):1290-1301. doi: 10.1080/03639045.2021.1989454. [PMID: 34620021]
  • Xinghua Liu, Heyuan Sun, Yumu Zhang, Yufei Sun, Wenyan Wang, Lixiao Xu, Wanhui Liu. Clozapine affects the pharmacokinetics of risperidone and inhibits its metabolism and P-glycoprotein-mediated transport in vivo and in vitro: A safety attention to antipsychotic polypharmacy with clozapine and risperidone. Toxicology and applied pharmacology. 2021 07; 422(?):115560. doi: 10.1016/j.taap.2021.115560. [PMID: 33957192]
  • Beate Klein, Christoph Silberbauer. [Rhabdomyolysis induced by paliperidone palmitate]. Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater. 2021 Jun; 35(2):98-101. doi: 10.1007/s40211-020-00377-3. [PMID: 33242202]
  • Zackary A Cope, Johnny A Kenton, Arpi Minassian, Maureen V Martin, William Perry, Christoffer Bundgaard, Jørn Arnt, Jordy van Enkhuizen, Mark A Geyer, Jared W Young. Chronic antipsychotic treatment exerts limited effects on the mania-like behavior of dopamine transporter knockdown mice. Behavioural brain research. 2021 05; 405(?):113167. doi: 10.1016/j.bbr.2021.113167. [PMID: 33577882]
  • Chengfang Zhang, Xiaodan Wang, Chengping Hu, Wenhua Ding, Han Li, Meng Wu, Manji Hu, Qiang Wang, Xirong Sun. The effect of prohibiting outside food during COVID-19 pandemic on the body weight of schizophrenic patients taking olanzapine or clozapine: a retrospective self-controlled study. Annals of palliative medicine. 2021 May; 10(5):5010-5016. doi: 10.21037/apm-20-2513. [PMID: 33894724]
  • Stefanie Fekete, Maike Scherf-Clavel, Manfred Gerlach, Marcel Romanos, Sarah Kittel-Schneider, Stefan Unterecker, Karin Egberts. Dose-Corrected Serum Concentrations and Metabolite to Parent Compound Ratios of Venlafaxine and Risperidone from Childhood to Old Age. Pharmacopsychiatry. 2021 May; 54(3):117-125. doi: 10.1055/a-1302-8108. [PMID: 33291155]
  • Rencheng Cai, Jinyan Zhao, Zhenguo Qiao, Yimei Li. Idiopathic granulomatous mastitis with normal prolactin level caused by risperidone. Asian journal of surgery. 2021 May; 44(5):763-764. doi: 10.1016/j.asjsur.2021.02.026. [PMID: 33757729]
  • Sebastian Masternak, Olga Padała, Hanna Karakuła-Juchnowicz. False-positive drug test results in patients taking psychotropic drugs. A literature review. Psychiatria polska. 2021 Apr; 55(2):435-446. doi: 10.12740/pp/113173. [PMID: 34365490]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Alberto Canfrán-Duque, Óscar Pastor, David García-Seisdedos, Yessenia L Molina, Bohdan Babiy, Milagros Lerma, Carmen Sánchez-Castellano, Javier Martínez-Botas, Diego Gómez-Coronado, Miguel A Lasunción, Alfonso J Cruz-Jentoft, Rebeca Busto. The Antipsychotic Risperidone Alters Dihydroceramide and Ceramide Composition and Plasma Membrane Function in Leukocytes In Vitro and In Vivo. International journal of molecular sciences. 2021 Apr; 22(8):. doi: 10.3390/ijms22083919. [PMID: 33920193]
  • George Bebawy, Magda Sokar, Ossama Y Abdallaha. Novel risperidone orally disintegrating minitablets for pediatric use: patient acceptance and dose adjustment. Drug development and industrial pharmacy. 2021 Apr; 47(4):542-551. doi: 10.1080/03639045.2021.1879829. [PMID: 33492181]
  • Xi Rong Li, Mei Hong Xiu, Xiao Ni Guan, Yue Chan Wang, Jun Wang, Edison Leung, Xiang Yang Zhang. Altered Antioxidant Defenses in Drug-Naive First Episode Patients with Schizophrenia Are Associated with Poor Treatment Response to Risperidone: 12-Week Results from a Prospective Longitudinal Study. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2021 04; 18(2):1316-1324. doi: 10.1007/s13311-021-01036-3. [PMID: 33791970]
  • Koji Otsuki, Muneto Izuhara, Shoko Miura, Satoko Yamashita, Michiharu Nagahama, Maiko Hayashida, Sadayuki Hashioka, Tsuyoshi Miyaoka, Yukie Hotta, Yasuhiko Shimizu, Masatoshi Inagaki. Psychosis in a primary hyperparathyroidism patient with mild hypercalcemia: A case report. Medicine. 2021 Mar; 100(12):e25248. doi: 10.1097/md.0000000000025248. [PMID: 33761720]
  • Catherine Parker, Aaron Slan, Daniel Shalev, Adam Critchfield. Abrupt Late-onset Psychosis as a Presentation of Coronavirus 2019 Disease (COVID-19): A Longitudinal Case Report. Journal of psychiatric practice. 2021 Mar; 27(2):131-136. doi: 10.1097/pra.0000000000000533. [PMID: 33656820]
  • Sanne Maartje Kloosterboer, Brenda C M de Winter, Catrien G Reichart, Mirjam E J Kouijzer, Matthias M J de Kroon, Emma van Daalen, Wietske A Ester, Rob Rieken, Gwen C Dieleman, Daphne van Altena, Beatrijs Bartelds, Ron H N van Schaik, Kazem Nasserinejad, Manon H J Hillegers, Teun van Gelder, Bram Dierckx, Birgit C P Koch. Risperidone plasma concentrations are associated with side effects and effectiveness in children and adolescents with autism spectrum disorder. British journal of clinical pharmacology. 2021 03; 87(3):1069-1081. doi: 10.1111/bcp.14465. [PMID: 32643213]
  • G Drevin, N Picard, N Jousset, M Briet, C Abbara. Pitfalls and challenges associated with phenoconversion in forensic toxcicology. Forensic science international. Genetics. 2021 03; 51(?):102433. doi: 10.1016/j.fsigen.2020.102433. [PMID: 33278816]
  • Dachun Chen, Hongna Li, Qing Zhao, Jiaqi Song, Chen Lin, Jianjin Yu. Effect of risperidone treatment on insulin-like growth factor-1 and interleukin-17 in drug naïve first-episode schizophrenia. Psychiatry research. 2021 03; 297(?):113717. doi: 10.1016/j.psychres.2021.113717. [PMID: 33503523]
  • Marc-André Nolin, Marie-France Demers, Chloé Rauzier, Roch-Hugo Bouchard, Camille Cadrin, Jean-Pierre Després, Marc-André Roy, Natalie Alméras, Frédéric Picard. Circulating IGFBP-2 levels reveal atherogenic metabolic risk in schizophrenic patients using atypical antipsychotics. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 2021 03; 22(3):175-182. doi: 10.1080/15622975.2020.1770858. [PMID: 32552257]
  • Yaowaluck Hongkaew, Andrea Gaedigk, Bob Wilffert, Nattawat Ngamsamut, Wiranpat Kittitharaphan, Penkhae Limsila, Chonlaphat Sukasem. Relationship between CYP2D6 genotype, activity score and phenotype in a pediatric Thai population treated with risperidone. Scientific reports. 2021 02; 11(1):4158. doi: 10.1038/s41598-021-83570-w. [PMID: 33603025]
  • Jinjun Lu, Ye Yang, Jian Lu, Zuqing Wang, Yiping He, Yeliang Yan, Kai Fu, Wenjuan Jiang, Yunqing Xu, Renrong Wu, Wenqing Liu, Jingping Zhao. Effect of CYP2D6 polymorphisms on plasma concentration and therapeutic effect of risperidone. BMC psychiatry. 2021 02; 21(1):70. doi: 10.1186/s12888-020-03034-9. [PMID: 33535976]
  • Gözde Görmüş, Sinem Ilgın, Merve Baysal, Abdullah Burak Karaduman, Volkan Kılıç, Gözde Aydoğan-Kılıç, Onur Karagöz, Özlem Atlı-Eklioğlu. Risperidone induced reproductive toxicity in male rats targeting leydig cells and hypothalamic-pituitary-gonadal axis by inducing oxidative stress. Andrologia. 2021 Feb; 53(1):e13813. doi: 10.1111/and.13813. [PMID: 33108826]
  • Burak Çakır, Şermin Yalın Sapmaz, Hasan Kandemir. Use of Antipsychotics: The Experiences, Views, and Monitoring Practices of Child and Adolescent Psychiatrists in Turkey. Journal of child and adolescent psychopharmacology. 2021 02; 31(1):73-78. doi: 10.1089/cap.2020.0078. [PMID: 32614261]
  • Hsiao-Pei Tsai, Po-Hsun Hou, Frank-Chiahung Mao, Chia-Chia Chang, Wei-Cheng Yang, Ching-Feng Wu, Huei-Jyuan Liao, Tzu-Chun Lin, Lan-Szu Chou, Li-Wei Hsiao, Geng-Ruei Chang. Risperidone Exacerbates Glucose Intolerance, Nonalcoholic Fatty Liver Disease, and Renal Impairment in Obese Mice. International journal of molecular sciences. 2021 Jan; 22(1):. doi: 10.3390/ijms22010409. [PMID: 33401717]
  • David P Walling, Howard A Hassman, Lourdes Anta, Lourdes Ochoa, Ignacio Ayani, Javier Martínez, Ibon Gutierro. The Steady-State Comparative Bioavailability of Intramuscular Risperidone ISM and Oral Risperidone: An Open-Label, One-Sequence Study. Drug design, development and therapy. 2021; 15(?):4371-4382. doi: 10.2147/dddt.s332026. [PMID: 34703212]
  • A S Ozornin, N V Govorin, A V Sakharov, P P Tereshkov. [Changes in adipokines in the blood of patients with the first episode of schizophrenia during treatment with haloperidol and risperidone]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2021; 121(9):58-62. doi: 10.17116/jnevro202112109158. [PMID: 34693690]
  • Heidi N Boyda, Ric M Procyshyn, Lurdes Tse, Jessica W Y Yuen, William G Honer, Alasdair M Barr. A comparison of the metabolic side-effects of the second-generation antipsychotic drugs risperidone and paliperidone in animal models. PloS one. 2021; 16(1):e0246211. doi: 10.1371/journal.pone.0246211. [PMID: 33508013]
  • Peter M Haddad, Majid Al Abdulla, Javed Latoo, Yousaf Iqbal. Brief psychotic disorder associated with quarantine and mild COVID-19. BMJ case reports. 2020 Dec; 13(12):. doi: 10.1136/bcr-2020-240088. [PMID: 33328211]
  • Sakshi Dhir, Zaira Khalid, Jisselly Salcedo, Alaa Shanbour. Acetyl-l-Carnitine and New-Onset Psychosis During the COVID-19 Pandemic. The primary care companion for CNS disorders. 2020 12; 22(6):. doi: 10.4088/pcc.20l02804. [PMID: 33271642]
  • Zhi Wei Wu, Hui Shi, Da Chun Chen, Song Chen, Mei Hong Xiu, Xiang Yang Zhang. BDNF serum levels and cognitive improvement in drug-naive first episode patients with schizophrenia: A prospective 12-week longitudinal study. Psychoneuroendocrinology. 2020 12; 122(?):104879. doi: 10.1016/j.psyneuen.2020.104879. [PMID: 33049658]
  • Tempei Ikegame, Miki Bundo, Naohiro Okada, Yui Murata, Shinsuke Koike, Hiroko Sugawara, Takeo Saito, Masashi Ikeda, Keiho Owada, Masaki Fukunaga, Fumio Yamashita, Daisuke Koshiyama, Tatsunobu Natsubori, Norichika Iwashiro, Tatsuro Asai, Akane Yoshikawa, Fumichika Nishimura, Yoshiya Kawamura, Jun Ishigooka, Chihiro Kakiuchi, Tsukasa Sasaki, Osamu Abe, Ryota Hashimoto, Nakao Iwata, Hidenori Yamasue, Tadafumi Kato, Kiyoto Kasai, Kazuya Iwamoto. Promoter Activity-Based Case-Control Association Study on SLC6A4 Highlighting Hypermethylation and Altered Amygdala Volume in Male Patients With Schizophrenia. Schizophrenia bulletin. 2020 12; 46(6):1577-1586. doi: 10.1093/schbul/sbaa075. [PMID: 32556264]
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