m344 (BioDeep_00000016534)
代谢物信息卡片
4-(Dimethylamino)-n-[7-(hydroxyamino)-7-oxoheptyl]benzamide
化学式: C16H25N3O3 (307.189582)
中文名称: M344
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN(C)C1=CC=C(C=C1)C(=O)NCCCCCCC(=O)NO
InChI: InChI=1S/C16H25N3O3/c1-19(2)14-10-8-13(9-11-14)16(21)17-12-6-4-3-5-7-15(20)18-22/h8-11,22H,3-7,12H2,1-2H3,(H,17,21)(H,18,20)
描述信息
D004791 - Enzyme Inhibitors > D056572 - Histone Deacetylase Inhibitors
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:125562
- KEGG: C74302
- PubChem: 3994
- DrugBank: DB02565
- ChEMBL: CHEMBL140000
- CAS: 251456-60-7
- PMhub: MS000242202
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- James H McMahon, Vanessa A Evans, Jillian S Y Lau, Jori Symons, Jennifer M Zerbato, Judy Chang, Ajantha Solomon, Surekha Tennakoon, Ashanti Dantanarayana, Michelle Hagenauer, Sulggi Lee, Sarah Palmer, Katie Fisher, Namandje Bumpus, Carley J S Heck, David Burger, Guoxin Wu, Paul Zuck, Bonnie J Howell, Henrik H Zetterberg, Kaj Blennow, Magnus Gisslen, Thomas A Rasmussen, Sharon R Lewin. Neurotoxicity with high-dose disulfiram and vorinostat used for HIV latency reversal.
AIDS (London, England).
2022 01; 36(1):75-82. doi:
10.1097/qad.0000000000003091. [PMID: 34586085] - Omnyah M O Bashraf, Ahmed S Ali, Hala S A Eweis, Soad S Ali. Protective Effects of Low Dose Vorinostat on Cisplatin-Induced Nephrotoxicity in Rats.
Current molecular pharmacology.
2021 10; 14(4):635-645. doi:
10.2174/1874467213666201209104335. [PMID: 33297925] - Yinshan Lin, Songpei Li, Zekuan Xiao, Sheng Chen, Langyu Yang, Qingsheng Peng, Huan Li, Jijun Fu, Xiyong Yu, Lingmin Zhang. Epigenetic inhibition assisted chemotherapeutic treatment of lung cancer based on artificial exosomes.
Pharmacological research.
2021 09; 171(?):105787. doi:
10.1016/j.phrs.2021.105787. [PMID: 34314859] - Yingying Wang, Qianying Zhu, Haihong Hu, Hong Zhu, Bo Yang, Qiaojun He, Lushan Yu, Su Zeng. Upregulation of histone acetylation reverses organic anion transporter 2 repression and enhances 5-fluorouracil sensitivity in hepatocellular carcinoma.
Biochemical pharmacology.
2021 06; 188(?):114546. doi:
10.1016/j.bcp.2021.114546. [PMID: 33838133] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Jennifer M Zerbato, Georges Khoury, Wei Zhao, Matthew J Gartner, Rachel D Pascoe, Ajantha Rhodes, Ashanti Dantanarayana, Megan Gooey, Jenny Anderson, Peter Bacchetti, Steven G Deeks, James McMahon, Michael Roche, Thomas A Rasmussen, Damian Fj Purcell, Sharon R Lewin. Multiply spliced HIV RNA is a predictive measure of virus production ex vivo and in vivo following reversal of HIV latency.
EBioMedicine.
2021 Mar; 65(?):103241. doi:
10.1016/j.ebiom.2021.103241. [PMID: 33647768] - Rachel E Carlisle, Salwa Farooqi, Ming Chan Zhang, Sarah Liu, Chao Lu, Andy Phan, Elise Brimble, Jeffrey G Dickhout. Inhibition of histone deacetylation with vorinostat does not prevent tunicamycin-mediated acute kidney injury.
PloS one.
2021; 16(11):e0260519. doi:
10.1371/journal.pone.0260519. [PMID: 34847196] - Ana M Molina, Johannes C van der Mijn, Paul Christos, John Wright, Charlene Thomas, Janice P Dutcher, David M Nanus, Scott T Tagawa, Lorraine J Gudas. NCI 6896: a phase I trial of vorinostat (SAHA) and isotretinoin (13-cis retinoic acid) in the treatment of patients with advanced renal cell carcinoma.
Investigational new drugs.
2020 10; 38(5):1383-1389. doi:
10.1007/s10637-019-00880-7. [PMID: 31898184] - Yongchang Li, Mingming Liu, Mohamed Abdo Rizk, Paul Franck Adjou Moumouni, Seung-Hun Lee, Eloiza May Galon, Huanping Guo, Yang Gao, Jixu Li, Amani Magdy Beshbishy, Arifin Budiman Nugraha, Shengwei Ji, Maria Agnes Tumwebaze, Byamukama Benedicto, Naoaki Yokoyama, Ikuo Igarashi, Xuenan Xuan. Drug screening of food and drug administration-approved compounds against Babesia bovis in vitro.
Experimental parasitology.
2020 Mar; 210(?):107831. doi:
10.1016/j.exppara.2020.107831. [PMID: 31926147] - Azam Shamsian, Mohammad Reza Sepand, Marziye Javaheri Kachousangi, Tahereh Dara, Seyed Nasser Ostad, Fatemeh Atyabi, Mohammad Hossein Ghahremani. Targeting Tumorigenicity of Breast Cancer Stem Cells Using SAHA/Wnt-b Catenin Antagonist Loaded Onto Protein Corona of Gold Nanoparticles.
International journal of nanomedicine.
2020; 15(?):4063-4078. doi:
10.2147/ijn.s234636. [PMID: 32606664] - Zhenjie Huang, Peng Wei, Luoman Gan, Tonghua Zeng, Caicheng Qin, Guangnan Liu. Role of Erythromycin-Regulated Histone Deacetylase-2 in Benign Tracheal Stenosis.
Canadian respiratory journal.
2020; 2020(?):4213807. doi:
10.1155/2020/4213807. [PMID: 32051729] - Kazuki Okubo, Makoto Isono, Kosuke Miyai, Takako Asano, Akinori Sato. Fluvastatin potentiates anticancer activity of vorinostat in renal cancer cells.
Cancer science.
2020 Jan; 111(1):112-126. doi:
10.1111/cas.14225. [PMID: 31675763] - Cornelis M van Tilburg, Till Milde, Ruth Witt, Jonas Ecker, Thomas Hielscher, Angelika Seitz, Jens-Peter Schenk, Juliane L Buhl, Dennis Riehl, Michael C Frühwald, Arnulf Pekrun, Claudia Rossig, Regina Wieland, Christian Flotho, Uwe Kordes, Bernd Gruhn, Thorsten Simon, Christin Linderkamp, Felix Sahm, Lenka Taylor, Angelika Freitag, Jürgen Burhenne, Kathrin I Foerster, Andreas D Meid, Stefan M Pfister, Irini Karapanagiotou-Schenkel, Olaf Witt. Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia.
Clinical epigenetics.
2019 12; 11(1):188. doi:
10.1186/s13148-019-0775-1. [PMID: 31823832] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Francis Mussai, Rachel Wheat, Evgenia Sarrou, Sarah Booth, Victoria Stavrou, Livingstone Fultang, Tracey Perry, Pamela Kearns, Paul Cheng, Karen Keeshan, Charles Craddock, Carmela De Santo. Targeting the arginine metabolic brake enhances immunotherapy for leukaemia.
International journal of cancer.
2019 10; 145(8):2201-2208. doi:
10.1002/ijc.32028. [PMID: 30485425] - Qianying Zhu, Lushan Yu, Zhiyuan Qin, Lu Chen, Haihong Hu, Xiaoli Zheng, Su Zeng. Regulation of OCT2 transcriptional repression by histone acetylation in renal cell carcinoma.
Epigenetics.
2019 08; 14(8):791-803. doi:
10.1080/15592294.2019.1615354. [PMID: 31088315] - Jin-Shu Pang, Zhe-Kun Li, Peng Lin, Xiao-Dong Wang, Gang Chen, Hai-Biao Yan, Sheng-Hua Li. The underlying molecular mechanism and potential drugs for treatment in papillary renal cell carcinoma: A study based on TCGA and Cmap datasets.
Oncology reports.
2019 Apr; 41(4):2089-2102. doi:
10.3892/or.2019.7014. [PMID: 30816528] - Sanjeev Kumar Sagwal, Gabriella Pasqual-Melo, Yana Bodnar, Rajesh Kumar Gandhirajan, Sander Bekeschus. Combination of chemotherapy and physical plasma elicits melanoma cell death via upregulation of SLC22A16.
Cell death & disease.
2018 12; 9(12):1179. doi:
10.1038/s41419-018-1221-6. [PMID: 30518936] - Yao Wang, Lei Zhao, Fang-Zhou Jiao, Wen-Bin Zhang, Qian Chen, Zuo-Jiong Gong. Histone deacetylase inhibitor suberoylanilide hydroxamic acid alleviates liver fibrosis by suppressing the transforming growth factor-β1 signal pathway.
Hepatobiliary & pancreatic diseases international : HBPD INT.
2018 Oct; 17(5):423-429. doi:
10.1016/j.hbpd.2018.09.013. [PMID: 30249543] - Athira Kv, Rajaram Mohanrao Madhana, Indu Chandran Js, Mangala Lahkar, Swapnil Sinha, V G M Naidu. Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice.
Behavioural brain research.
2018 05; 344(?):73-84. doi:
10.1016/j.bbr.2018.02.009. [PMID: 29452193] - Jing Liu, Man J Livingston, Guie Dong, Chengyuan Tang, Yunchao Su, Guangyu Wu, Xiao-Ming Yin, Zheng Dong. Histone deacetylase inhibitors protect against cisplatin-induced acute kidney injury by activating autophagy in proximal tubular cells.
Cell death & disease.
2018 02; 9(3):322. doi:
10.1038/s41419-018-0374-7. [PMID: 29476062] - Roisin M Connolly, Mary Jo Fackler, Zhe Zhang, Xian C Zhou, Matthew P Goetz, Judy C Boughey, Bridget Walsh, John T Carpenter, Anna Maria Storniolo, Stanley P Watkins, Edward W Gabrielson, Vered Stearns, Saraswati Sukumar. Tumor and serum DNA methylation in women receiving preoperative chemotherapy with or without vorinostat in TBCRC008.
Breast cancer research and treatment.
2018 01; 167(1):107-116. doi:
10.1007/s10549-017-4503-2. [PMID: 28918548] - J Yu, H Wu, Z Lin, K Su, J Zhang, F Sun, X Wang, C Wen, H Cao, L Hu. Metabolic changes in rat serum after administration of suberoylanilide hydroxamic acid and discriminated by SVM.
Human & experimental toxicology.
2017 Dec; 36(12):1286-1294. doi:
10.1177/0960327116688067. [PMID: 28084089] - A Arhoma, A D Chantry, S L Haywood-Small, N A Cross. SAHA-induced TRAIL-sensitisation of Multiple Myeloma cells is enhanced in 3D cell culture.
Experimental cell research.
2017 11; 360(2):226-235. doi:
10.1016/j.yexcr.2017.09.012. [PMID: 28890292] - Hong Guo, Jie Zhang, Yaping Wang, Chen Bu, Yanyan Zhou, Qin Fang. Comparative Proteomic Analysis of Lysine Acetylation in Fish CIK Cells Infected with Aquareovirus.
International journal of molecular sciences.
2017 Nov; 18(11):. doi:
10.3390/ijms18112419. [PMID: 29135940] - Jürgen Burhenne, Lu Liu, Christoph E Heilig, Andreas D Meid, Margarete Leisen, Thomas Schmitt, Bernd Kasper, Walter E Haefeli, Gerd Mikus, Gerlinde Egerer. Intracellular vorinostat accumulation and its relationship to histone deacetylase activity in soft tissue sarcoma patients.
Cancer chemotherapy and pharmacology.
2017 Aug; 80(2):433-439. doi:
10.1007/s00280-017-3357-y. [PMID: 28612091] - Jie Lu, Grégoire P Chatain, Alejandro Bugarini, Xiang Wang, Dragan Maric, Stuart Walbridge, Zhengping Zhuang, Prashant Chittiboina. Histone Deacetylase Inhibitor SAHA Is a Promising Treatment of Cushing Disease.
The Journal of clinical endocrinology and metabolism.
2017 08; 102(8):2825-2835. doi:
10.1210/jc.2017-00464. [PMID: 28505327] - Talia M Mota, Thomas A Rasmussen, Ajantha Rhodes, Surekha Tennakoon, Ashanti Dantanarayana, Fiona Wightman, Michelle Hagenauer, Janine Roney, Tim Spelman, Damian F J Purcell, James McMahon, Jennifer F Hoy, H Miles Prince, Julian H Elliott, Sharon R Lewin. No adverse safety or virological changes 2 years following vorinostat in HIV-infected individuals on antiretroviral therapy.
AIDS (London, England).
2017 05; 31(8):1137-1141. doi:
10.1097/qad.0000000000001442. [PMID: 28301423] - Ming Jang Chua, Megan S J Arnold, Weijun Xu, Julien Lancelot, Suzanne Lamotte, Gerald F Späth, Eric Prina, Raymond J Pierce, David P Fairlie, Tina S Skinner-Adams, Katherine T Andrews. Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth.
International journal for parasitology. Drugs and drug resistance.
2017 04; 7(1):42-50. doi:
10.1016/j.ijpddr.2016.12.005. [PMID: 28107750] - Roberto Pili, Glenn Liu, Sreenivasulu Chintala, Hendrick Verheul, Shabnam Rehman, Kristopher Attwood, Martin A Lodge, Richard Wahl, James I Martin, Kiersten Marie Miles, Silvia Paesante, Remi Adelaiye, Alejandro Godoy, Serina King, James Zwiebel, Michael A Carducci. Combination of the histone deacetylase inhibitor vorinostat with bevacizumab in patients with clear-cell renal cell carcinoma: a multicentre, single-arm phase I/II clinical trial.
British journal of cancer.
2017 Mar; 116(7):874-883. doi:
10.1038/bjc.2017.33. [PMID: 28222071] - Abdul Waheed Khan, Mark Ziemann, Susan J Corcoran, Harikrishnan K N, Jun Okabe, Haloom Rafehi, Scott S Maxwell, Murray D Esler, Assam El-Osta. NET silencing by let-7i in postural tachycardia syndrome.
JCI insight.
2017 03; 2(6):e90183. doi:
10.1172/jci.insight.90183. [PMID: 28352654] - Andrew B Munkacsi, Natalie Hammond, Remy T Schneider, Dinindu S Senanayake, Katsumi Higaki, Kirill Lagutin, Stephen J Bloor, Daniel S Ory, Robert A Maue, Fannie W Chen, Antonio Hernandez-Ono, Nicole Dahlson, Joyce J Repa, Henry N Ginsberg, Yiannis A Ioannou, Stephen L Sturley. Normalization of Hepatic Homeostasis in the Npc1nmf164 Mouse Model of Niemann-Pick Type C Disease Treated with the Histone Deacetylase Inhibitor Vorinostat.
The Journal of biological chemistry.
2017 03; 292(11):4395-4410. doi:
10.1074/jbc.m116.770578. [PMID: 28031458] - Nethrie D Idippily, Chunfang Gan, Paul Orefice, Jane Peterson, Bin Su. Synthesis of Vorinostat and cholesterol conjugate to enhance the cancer cell uptake selectivity.
Bioorganic & medicinal chemistry letters.
2017 02; 27(4):816-820. doi:
10.1016/j.bmcl.2017.01.025. [PMID: 28108250] - P S Suresh, V C Devaraj, Nuggehally R Srinivas, Ramesh Mullangi. Review of bioanalytical assays for the quantitation of various HDAC inhibitors such as vorinostat, belinostat, panobinostat, romidepsin and chidamine.
Biomedical chromatography : BMC.
2017 Jan; 31(1):. doi:
10.1002/bmc.3807. [PMID: 27511598] - I Burianova, K Kuzelova, O Mitrovsky, I Spicka, P Stockbauer, M Zackova. Histone deacetylase inhibitors in plasma cell leukemia treatment: effect of bone marrow microenvironment.
Neoplasma.
2017 ; 64(2):228-237. doi:
10.4149/neo_2017_209. [PMID: 28043150] - Chao Wang, Marion Bouchecareilh, William E Balch. Measuring the Effect of Histone Deacetylase Inhibitors (HDACi) on the Secretion and Activity of Alpha-1 Antitrypsin.
Methods in molecular biology (Clifton, N.J.).
2017; 1639(?):185-193. doi:
10.1007/978-1-4939-7163-3_18. [PMID: 28752458] - Elham Abdelmonem Mohamed, Irhan Ibrahim Abu Hashim, Rehab Mohammad Yusif, Ghada Mohamed Suddek, Ahmed Abdel Aziz Shaaban, Farid Abd Elreheem Badria. Enhanced in vitro cytotoxicity and anti-tumor activity of vorinostat-loaded pluronic micelles with prolonged release and reduced hepatic and renal toxicities.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2017 Jan; 96(?):232-242. doi:
10.1016/j.ejps.2016.09.029. [PMID: 27667706] - Jiaoyang Li, Xizi Wu, Yao Chen, Renqing Zeng, Yangzi Zhao, Panpan Chang, Danna Wang, Qianwen Zhao, Yunlei Deng, Yongqing Li, Hasan B Alam, Wei Chong. The Effects of Molecular Hydrogen and Suberoylanilide Hydroxamic Acid on Paraquat-Induced Production of Reactive Oxygen Species and TNF-α in Macrophages.
Inflammation.
2016 Dec; 39(6):1990-1996. doi:
10.1007/s10753-016-0434-z. [PMID: 27624060] - Daniel Patschan, Katrin Schwarze, Elvira Henze, Susann Patschan, Gerhard Anton Müller. Endothelial autophagy and Endothelial-to-Mesenchymal Transition (EndoMT) in eEPC treatment of ischemic AKI.
Journal of nephrology.
2016 Oct; 29(5):637-44. doi:
10.1007/s40620-015-0222-0. [PMID: 26289253] - Eugenio Gaudio, Chiara Tarantelli, Maurilio Ponzoni, Elodie Odore, Keyvan Rezai, Elena Bernasconi, Luciano Cascione, Andrea Rinaldi, Anastasios Stathis, Eugenia Riveiro, Esteban Cvitkovic, Emanuele Zucca, Francesco Bertoni. Bromodomain inhibitor OTX015 (MK-8628) combined with targeted agents shows strong in vivo antitumor activity in lymphoma.
Oncotarget.
2016 Sep; 7(36):58142-58147. doi:
10.18632/oncotarget.10983. [PMID: 27494885] - Hang Lu, Xue-Feng Yang, Xiao-Qing Tian, Shou-Long Tang, Lian-Qian Li, Shuang Zhao, Hua-Chuan Zheng. The in vitro and vivo anti-tumor effects and molecular mechanisms of suberoylanilide hydroxamic acid (SAHA) and MG132 on the aggressive phenotypes of gastric cancer cells.
Oncotarget.
2016 Aug; 7(35):56508-56525. doi:
10.18632/oncotarget.10643. [PMID: 27447743] - Wendy L van der Woerd, Catharina G K Wichers, Anna L Vestergaard, Jens Peter Andersen, Coen C Paulusma, Roderick H J Houwen, Stan F J van de Graaf. Rescue of defective ATP8B1 trafficking by CFTR correctors as a therapeutic strategy for familial intrahepatic cholestasis.
Journal of hepatology.
2016 06; 64(6):1339-47. doi:
10.1016/j.jhep.2016.02.001. [PMID: 26879107] - Changhoon Yoo, Min-Hee Ryu, Young-Soon Na, Baek-Yeol Ryoo, Chae-Won Lee, Yoon-Koo Kang. Vorinostat in combination with capecitabine plus cisplatin as a first-line chemotherapy for patients with metastatic or unresectable gastric cancer: phase II study and biomarker analysis.
British journal of cancer.
2016 May; 114(11):1185-90. doi:
10.1038/bjc.2016.125. [PMID: 27172248] - Chiara Ciardiello, Maria Serena Roca, Alessia Noto, Francesca Bruzzese, Tania Moccia, Carlo Vitagliano, Elena Di Gennaro, Gennaro Ciliberto, Giuseppe Roscilli, Luigi Aurisicchio, Emanuele Marra, Rita Mancini, Alfredo Budillon, Alessandra Leone. Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression.
Oncotarget.
2016 Apr; 7(15):19559-74. doi:
10.18632/oncotarget.7195. [PMID: 26862736] - Michal Yalon, Liron Tuval-Kochen, David Castel, Itai Moshe, Inbal Mazal, Osher Cohen, Camila Avivi, Kineret Rosenblatt, Sarit Aviel-Ronen, Ginette Schiby, Joachim Yahalom, Ninette Amariglio, Raphael Pfeffer, Yaacov Lawrence, Amos Toren, Gideon Rechavi, Shoshana Paglin. Overcoming Resistance of Cancer Cells to PARP-1 Inhibitors with Three Different Drug Combinations.
PloS one.
2016; 11(5):e0155711. doi:
10.1371/journal.pone.0155711. [PMID: 27196668] - Iel-Yong Sung, Han-Na Son, Imran Ullah, Dinesh Bharti, Ju-Mi Park, Yeong-Cheol Cho, June-Ho Byun, Young-Hoon Kang, Su-Jin Sung, Jong-Woo Kim, Gyu-Jin Rho, Bong-Wook Park. Cardiomyogenic Differentiation of Human Dental Follicle-derived Stem Cells by Suberoylanilide Hydroxamic Acid and Their In Vivo Homing Property.
International journal of medical sciences.
2016; 13(11):841-852. doi:
10.7150/ijms.16573. [PMID: 27877076] - Salma Afifi, Angela Michael, Mahshid Azimi, Mabel Rodriguez, Nikoletta Lendvai, Ola Landgren. Role of Histone Deacetylase Inhibitors in Relapsed Refractory Multiple Myeloma: A Focus on Vorinostat and Panobinostat.
Pharmacotherapy.
2015 Dec; 35(12):1173-88. doi:
10.1002/phar.1671. [PMID: 26684557] - Matthew Zibelman, Yu-Ning Wong, Karthik Devarajan, Lois Malizzia, Alycia Corrigan, Anthony J Olszanski, Crystal S Denlinger, Susan K Roethke, Colleen H Tetzlaff, Elizabeth R Plimack. Phase I study of the mTOR inhibitor ridaforolimus and the HDAC inhibitor vorinostat in advanced renal cell carcinoma and other solid tumors.
Investigational new drugs.
2015 Oct; 33(5):1040-7. doi:
10.1007/s10637-015-0261-3. [PMID: 26091915] - Li Wang, Wei Chen, Zhongjiang Peng, Changcheng Liu, Caihong Zhang, Zhiyong Guo. Vorinostat protects against calcium oxalate-induced kidney injury in mice.
Molecular medicine reports.
2015 Sep; 12(3):4291-4297. doi:
10.3892/mmr.2015.3964. [PMID: 26095064] - T Miyagaki, M Sugaya, T Oka, H Fujita, S Sato. Serum chemokine levels differentially regulated by vorinostat in a Sézary syndrome patient.
The British journal of dermatology.
2015 Aug; 173(2):620-2. doi:
10.1111/bjd.13696. [PMID: 25640919] - Steven G DuBois, Susan Groshen, Julie R Park, Daphne A Haas-Kogan, Xiaodong Yang, Ethan Geier, Eugene Chen, Kathy Giacomini, Brian Weiss, Susan L Cohn, M Meaghan Granger, Gregory A Yanik, Randall Hawkins, Jesse Courtier, Hollie Jackson, Fariba Goodarzian, Hiroyuki Shimada, Scarlett Czarnecki, Denice Tsao-Wei, Judith G Villablanca, Araz Marachelian, Katherine K Matthay. Phase I Study of Vorinostat as a Radiation Sensitizer with 131I-Metaiodobenzylguanidine (131I-MIBG) for Patients with Relapsed or Refractory Neuroblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2015 Jun; 21(12):2715-21. doi:
10.1158/1078-0432.ccr-14-3240. [PMID: 25695691] - Mauhamad Baarine, Craig Beeson, Avtar Singh, Inderjit Singh. ABCD1 deletion-induced mitochondrial dysfunction is corrected by SAHA: implication for adrenoleukodystrophy.
Journal of neurochemistry.
2015 May; 133(3):380-96. doi:
10.1111/jnc.12992. [PMID: 25393703] - Kang Lu, Xiao-sheng Fang, Li-li Feng, Yu-jie Jiang, Xiang-xiang Zhou, Xin Liu, Pei-pei Li, Na Chen, Mei Ding, Na Wang, Jie Zhang, Xin Wang. The STAT3 inhibitor WP1066 reverses the resistance of chronic lymphocytic leukemia cells to histone deacetylase inhibitors induced by interleukin-6.
Cancer letters.
2015 Apr; 359(2):250-8. doi:
10.1016/j.canlet.2015.01.021. [PMID: 25636517] - Sung Won Choi, Erin Gatza, Guoqing Hou, Yaping Sun, Joel Whitfield, Yeohan Song, Katherine Oravecz-Wilson, Isao Tawara, Charles A Dinarello, Pavan Reddy. Histone deacetylase inhibition regulates inflammation and enhances Tregs after allogeneic hematopoietic cell transplantation in humans.
Blood.
2015 Jan; 125(5):815-9. doi:
10.1182/blood-2014-10-605238. [PMID: 25428224] - Dong-Yun Han, Xiao-Jing Di, Yan-Lin Fu, Ting-Wei Mu. Combining valosin-containing protein (VCP) inhibition and suberanilohydroxamic acid (SAHA) treatment additively enhances the folding, trafficking, and function of epilepsy-associated γ-aminobutyric acid, type A (GABAA) receptors.
The Journal of biological chemistry.
2015 Jan; 290(1):325-37. doi:
10.1074/jbc.m114.580324. [PMID: 25406314] - Kezhi Lin, Qingwei Zhang, Zezheng Liu, Suping Yang, Yingying Lin, Congcong Wen, Yuancai Zheng. Effects of suberoylanilide hydroxamic acid on rat cytochrome P450 enzyme activities.
International journal of clinical and experimental pathology.
2015; 8(5):5584-90. doi:
. [PMID: 26191268] - Vindhya Koppaka, Neema Lakshman, W Matthew Petroll. Effect of HDAC Inhibitors on Corneal Keratocyte Mechanical Phenotypes in 3-D Collagen Matrices.
Molecular vision.
2015; 21(?):502-14. doi:
. [PMID: 25999677] - Ajay Sharma, Nishant R Sinha, Saad Siddiqui, Rajiv R Mohan. Role of 5'TG3'-interacting factors (TGIFs) in Vorinostat (HDAC inhibitor)-mediated Corneal Fibrosis Inhibition.
Molecular vision.
2015; 21(?):974-84. doi:
. [PMID: 26330748] - Feiyan Lin, Shuanghu Wang, Yunfang Zhou, Chunmei Wu, Huilong Zou, Peiwu Geng, Qingwei Zhang, Xiuhua Zhang. Pharmacokinetic interaction study combining lapatinib with vorinostat in rats.
Pharmacology.
2015; 95(3-4):160-5. doi:
10.1159/000380954. [PMID: 25896603] - Nassera Aouali, Angeliki Broukou, Manon Bosseler, Olivier Keunen, Vincent Schlesser, Bassam Janji, Valerie Palissot, Philippe Stordeur, Guy Berchem. Epigenetic Activity of Peroxisome Proliferator-Activated Receptor Gamma Agonists Increases the Anticancer Effect of Histone Deacetylase Inhibitors on Multiple Myeloma Cells.
PloS one.
2015; 10(6):e0130339. doi:
10.1371/journal.pone.0130339. [PMID: 26091518] - Carwyn Davies, Linda A Hogarth, Karen L Mackenzie, Andrew G Hall, Richard B Lock. p21(WAF1) modulates drug-induced apoptosis and cell cycle arrest in B-cell precursor acute lymphoblastic leukemia.
Cell cycle (Georgetown, Tex.).
2015; 14(22):3602-12. doi:
10.1080/15384101.2015.1100774. [PMID: 26506264] - Tuan Hiep Tran, Ju Yeon Choi, Thiruganesh Ramasamy, Duy Hieu Truong, Chien Ngoc Nguyen, Han-Gon Choi, Chul Soon Yong, Jong Oh Kim. Hyaluronic acid-coated solid lipid nanoparticles for targeted delivery of vorinostat to CD44 overexpressing cancer cells.
Carbohydrate polymers.
2014 Dec; 114(?):407-415. doi:
10.1016/j.carbpol.2014.08.026. [PMID: 25263908] - Gregory Q Del Prete, Rebecca Shoemaker, Kelli Oswald, Abigail Lara, Charles M Trubey, Randy Fast, Douglas K Schneider, Rebecca Kiser, Vicky Coalter, Adam Wiles, Rodney Wiles, Brandi Freemire, Brandon F Keele, Jacob D Estes, Octavio A Quiñones, Jeremy Smedley, Rhonda Macallister, Rosa I Sanchez, John S Wai, Christopher M Tan, W Gregory Alvord, Daria J Hazuda, Michael Piatak, Jeffrey D Lifson. Effect of suberoylanilide hydroxamic acid (SAHA) administration on the residual virus pool in a model of combination antiretroviral therapy-mediated suppression in SIVmac239-infected indian rhesus macaques.
Antimicrobial agents and chemotherapy.
2014 Nov; 58(11):6790-806. doi:
10.1128/aac.03746-14. [PMID: 25182644] - Julian H Elliott, Fiona Wightman, Ajantha Solomon, Khader Ghneim, Jeffrey Ahlers, Mark J Cameron, Miranda Z Smith, Tim Spelman, James McMahon, Pushparaj Velayudham, Gregor Brown, Janine Roney, Jo Watson, Miles H Prince, Jennifer F Hoy, Nicolas Chomont, Rémi Fromentin, Francesco A Procopio, Joumana Zeidan, Sarah Palmer, Lina Odevall, Ricky W Johnstone, Ben P Martin, Elizabeth Sinclair, Steven G Deeks, Daria J Hazuda, Paul U Cameron, Rafick-Pierre Sékaly, Sharon R Lewin. Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy.
PLoS pathogens.
2014 Oct; 10(10):e1004473. doi:
10.1371/journal.ppat.1004473. [PMID: 25393648] - Nancy M Archin, Rosalie Bateson, Manoj K Tripathy, Amanda M Crooks, Kuo-Hsiung Yang, Noelle P Dahl, Mary F Kearney, Elizabeth M Anderson, John M Coffin, Matthew C Strain, Douglas D Richman, Kevin R Robertson, Angela D Kashuba, Ronald J Bosch, Daria J Hazuda, Joann D Kuruc, Joseph J Eron, David M Margolis. HIV-1 expression within resting CD4+ T cells after multiple doses of vorinostat.
The Journal of infectious diseases.
2014 Sep; 210(5):728-35. doi:
10.1093/infdis/jiu155. [PMID: 24620025] - Renu Sankar, Vilwanathan Ravikumar. Biocompatibility and biodistribution of suberoylanilide hydroxamic acid loaded poly (DL-lactide-co-glycolide) nanoparticles for targeted drug delivery in cancer.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2014 Sep; 68(7):865-71. doi:
10.1016/j.biopha.2014.07.015. [PMID: 25107842] - Lu Liu, Jan-Christoph Detering, Till Milde, Walter Emil Haefeli, Olaf Witt, Jürgen Burhenne. Quantification of vorinostat and its main metabolites in plasma and intracellular vorinostat in PBMCs by liquid chromatography coupled to tandem mass spectrometry and its relation to histone deacetylase activity in human blood.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2014 Aug; 964(?):212-21. doi:
10.1016/j.jchromb.2014.02.014. [PMID: 24636840] - Tuan Hiep Tran, Thiruganesh Ramasamy, Duy Hieu Truong, Beom Soo Shin, Han-Gon Choi, Chul Soon Yong, Jong Oh Kim. Development of vorinostat-loaded solid lipid nanoparticles to enhance pharmacokinetics and efficacy against multidrug-resistant cancer cells.
Pharmaceutical research.
2014 Aug; 31(8):1978-88. doi:
10.1007/s11095-014-1300-z. [PMID: 24562809] - Samantha J McDonnel, Molly L Liepnieks, Brian G Murphy. Treatment of chronically FIV-infected cats with suberoylanilide hydroxamic acid.
Antiviral research.
2014 Aug; 108(?):74-8. doi:
10.1016/j.antiviral.2014.05.014. [PMID: 24954265] - Noemi Reguart, Rafael Rosell, Felipe Cardenal, Andres F Cardona, Dolores Isla, Ramon Palmero, Teresa Moran, Christian Rolfo, M Cinta Pallarès, Amelia Insa, Enric Carcereny, Margarita Majem, Javier De Castro, Cristina Queralt, Miguel A Molina, Miquel Taron. Phase I/II trial of vorinostat (SAHA) and erlotinib for non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations after erlotinib progression.
Lung cancer (Amsterdam, Netherlands).
2014 May; 84(2):161-7. doi:
10.1016/j.lungcan.2014.02.011. [PMID: 24636848] - S J McDonnel, L A Tell, B G Murphy. Pharmacokinetics and pharmacodynamics of suberoylanilide hydroxamic acid in cats.
Journal of veterinary pharmacology and therapeutics.
2014 Apr; 37(2):196-200. doi:
10.1111/jvp.12088. [PMID: 24236915] - Min Xie, Yongli Kong, Wei Tan, Herman May, Pavan K Battiprolu, Zully Pedrozo, Zhao V Wang, Cyndi Morales, Xiang Luo, Geoffrey Cho, Nan Jiang, Michael E Jessen, John J Warner, Sergio Lavandero, Thomas G Gillette, Aslan T Turer, Joseph A Hill. Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy.
Circulation.
2014 Mar; 129(10):1139-51. doi:
10.1161/circulationaha.113.002416. [PMID: 24396039] - Karolina Varga, Katalin Pászty, Rita Padányi, Luca Hegedűs, Jean-Philippe Brouland, Béla Papp, Agnes Enyedi. Histone deacetylase inhibitor- and PMA-induced upregulation of PMCA4b enhances Ca2+ clearance from MCF-7 breast cancer cells.
Cell calcium.
2014 Feb; 55(2):78-92. doi:
10.1016/j.ceca.2013.12.003. [PMID: 24439526] - Binhua Ling, Michael Piatak, Linda Rogers, Ann-Marie Johnson, Kasi Russell-Lodrigue, Daria J Hazuda, Jeffrey D Lifson, Ronald S Veazey. Effects of treatment with suppressive combination antiretroviral drug therapy and the histone deacetylase inhibitor suberoylanilide hydroxamic acid; (SAHA) on SIV-infected Chinese rhesus macaques.
PloS one.
2014; 9(7):e102795. doi:
10.1371/journal.pone.0102795. [PMID: 25033210] - Yan Wang, Sheng Tu, Dana Steffen, May Xiong. Iron complexation to histone deacetylase inhibitors SAHA and LAQ824 in PEGylated liposomes can considerably improve pharmacokinetics in rats.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.
2014; 17(4):583-602. doi:
10.18433/j3ts4v. [PMID: 25579435] - Nunung Yuniarti, Berry Juliandi, Chai MuhChyi, Hirofumi Noguchi, Tsukasa Sanosaka, Kinichi Nakashima. Prenatal exposure to suberoylanilide hydroxamic acid perturbs corticogenesis.
Neuroscience research.
2013 Sep; 77(1-2):42-9. doi:
10.1016/j.neures.2013.06.004. [PMID: 23831515] - Miriam Schiffgen, Doris H Schmidt, Alexander von Rücker, Stefan C Müller, Jörg Ellinger. Epigenetic regulation of microRNA expression in renal cell carcinoma.
Biochemical and biophysical research communications.
2013 Jun; 436(1):79-84. doi:
10.1016/j.bbrc.2013.05.061. [PMID: 23707942] - F Lai, S T Guo, L Jin, C C Jiang, C Y Wang, A Croft, M N Chi, H-Y Tseng, M Farrelly, B Atmadibrata, J Norman, T Liu, P Hersey, X D Zhang. Cotargeting histone deacetylases and oncogenic BRAF synergistically kills human melanoma cells by necrosis independently of RIPK1 and RIPK3.
Cell death & disease.
2013 Jun; 4(?):e655. doi:
10.1038/cddis.2013.192. [PMID: 23744355] - Adam Obr, Pavla Röselová, Dana Grebeňová, Kateřina Kuželová. Real-time monitoring of hematopoietic cell interaction with fibronectin fragment: the effect of histone deacetylase inhibitors.
Cell adhesion & migration.
2013 May; 7(3):275-82. doi:
10.4161/cam.24531. [PMID: 23567296] - Song Xu, Kim De Veirman, Holly Evans, Gaia Cecilia Santini, Isabelle Vande Broek, Xavier Leleu, Ann De Becker, Ben Van Camp, Peter Croucher, Karin Vanderkerken, Ivan Van Riet. Effect of the HDAC inhibitor vorinostat on the osteogenic differentiation of mesenchymal stem cells in vitro and bone formation in vivo.
Acta pharmacologica Sinica.
2013 May; 34(5):699-709. doi:
10.1038/aps.2012.182. [PMID: 23564084] - Beata Holkova, Jeffrey G Supko, Matthew M Ames, Joel M Reid, Geoffrey I Shapiro, Edward Brent Perkins, Viswanathan Ramakrishnan, Mary Beth Tombes, Connie Honeycutt, Renee M McGovern, Maciej Kmieciak, Ellen Shrader, Martha D Wellons, Heidi Sankala, Austin Doyle, John Wright, John D Roberts, Steven Grant. A phase I trial of vorinostat and alvocidib in patients with relapsed, refractory, or poor prognosis acute leukemia, or refractory anemia with excess blasts-2.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2013 Apr; 19(7):1873-83. doi:
10.1158/1078-0432.ccr-12-2926. [PMID: 23515411] - Yifei Zhong, Edward Y Chen, Ruijie Liu, Peter Y Chuang, Sandeep K Mallipattu, Christopher M Tan, Neil R Clark, Yueyi Deng, Paul E Klotman, Avi Ma'ayan, John Cijiang He. Renoprotective effect of combined inhibition of angiotensin-converting enzyme and histone deacetylase.
Journal of the American Society of Nephrology : JASN.
2013 Apr; 24(5):801-11. doi:
10.1681/asn.2012060590. [PMID: 23559582] - A Dasari, L Gore, W A Messersmith, S Diab, A Jimeno, C D Weekes, K D Lewis, H A Drabkin, T W Flaig, D R Camidge. A phase I study of sorafenib and vorinostat in patients with advanced solid tumors with expanded cohorts in renal cell carcinoma and non-small cell lung cancer.
Investigational new drugs.
2013 Feb; 31(1):115-25. doi:
10.1007/s10637-012-9812-z. [PMID: 22415798] - Michele Cea, Antonia Cagnetta, Marco Gobbi, Franco Patrone, Paul G Richardson, Teru Hideshima, Kenneth C Anderson. New insights into the treatment of multiple myeloma with histone deacetylase inhibitors.
Current pharmaceutical design.
2013; 19(4):734-44. doi:
NULL. [PMID: 23016853] - Marion Bouchecareilh, Darren M Hutt, Patricia Szajner, Terence R Flotte, William E Balch. Histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA)-mediated correction of α1-antitrypsin deficiency.
The Journal of biological chemistry.
2012 Nov; 287(45):38265-78. doi:
10.1074/jbc.m112.404707. [PMID: 22995909] - David R Jones, Christopher A Moskaluk, Heidi H Gillenwater, Gina R Petroni, Sandra G Burks, Jennifer Philips, Patrice K Rehm, Juan Olazagasti, Benjamin D Kozower, Yongde Bao. Phase I trial of induction histone deacetylase and proteasome inhibition followed by surgery in non-small-cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2012 Nov; 7(11):1683-90. doi:
10.1097/jto.0b013e318267928d. [PMID: 23059775] - Elham A Mohamed, Yunqi Zhao, Mahasen M Meshali, Connie M Remsberg, Thanaa M Borg, Abdel Monem M Foda, Jody K Takemoto, Casey L Sayre, Stephanie E Martinez, Neal M Davies, M Laird Forrest. Vorinostat with sustained exposure and high solubility in poly(ethylene glycol)-b-poly(DL-lactic acid) micelle nanocarriers: characterization and effects on pharmacokinetics in rat serum and urine.
Journal of pharmaceutical sciences.
2012 Oct; 101(10):3787-98. doi:
10.1002/jps.23265. [PMID: 22806441] - Ann P Bosiack, Elizabeth A Giuliano, Rangan Gupta, Rajiv R Mohan. Efficacy and safety of suberoylanilide hydroxamic acid (Vorinostat) in the treatment of canine corneal fibrosis.
Veterinary ophthalmology.
2012 Sep; 15(5):307-14. doi:
10.1111/j.1463-5224.2011.00985.x. [PMID: 22212187] - Mi Joung Kim, Dong Eun Kim, In Gab Jeong, Jene Choi, Sejin Jang, Je-Hwan Lee, Seonggu Ro, Jung Jin Hwang, Choung-Soo Kim. HDAC inhibitors synergize antiproliferative effect of sorafenib in renal cell carcinoma cells.
Anticancer research.
2012 Aug; 32(8):3161-8. doi:
NULL. [PMID: 22843888] - Thomas Asklund, Samuel Kvarnbrink, Camilla Holmlund, Carl Wibom, Tommy Bergenheim, Roger Henriksson, Håkan Hedman. Synergistic killing of glioblastoma stem-like cells by bortezomib and HDAC inhibitors.
Anticancer research.
2012 Jul; 32(7):2407-13. doi:
NULL. [PMID: 22753697] - Ji-young Kim, Gayong Shim, Hyun-woo Choi, Jooho Park, Seung Woo Chung, Sunil Kim, Kwangmeyung Kim, Ick Chan Kwon, Chan-Wha Kim, Sang Yoon Kim, Victor C Yang, Yu-Kyoung Oh, Youngro Byun. Tumor vasculature targeting following co-delivery of heparin-taurocholate conjugate and suberoylanilide hydroxamic acid using cationic nanolipoplex.
Biomaterials.
2012 Jun; 33(17):4424-30. doi:
10.1016/j.biomaterials.2012.02.066. [PMID: 22425551] - Akinori Sato, Takako Asano, Keiichi Ito, Makoto Sumitomo, Tomohiko Asano. Suberoylanilide hydroxamic acid (SAHA) combined with bortezomib inhibits renal cancer growth by enhancing histone acetylation and protein ubiquitination synergistically.
BJU international.
2012 Apr; 109(8):1258-68. doi:
10.1111/j.1464-410x.2011.10533.x. [PMID: 21895936] - Prakash Chinnaiyan, Sajeel Chowdhary, Lisa Potthast, Antony Prabhu, Ya-Yu Tsai, Bhaswati Sarcar, Soumen Kahali, Steven Brem, H Michael Yu, Amyn Rojiani, Ryan Murtagh, Edward Pan. Phase I trial of vorinostat combined with bevacizumab and CPT-11 in recurrent glioblastoma.
Neuro-oncology.
2012 Jan; 14(1):93-100. doi:
10.1093/neuonc/nor187. [PMID: 22028388] - Chien-Hsing Chang, Jorma Hinkula, Meiyu Loo, Tina Falkeborn, Rongxiu Li, Thomas M Cardillo, Edmund A Rossi, David M Goldenberg, Britta Wahren. A novel class of anti-HIV agents with multiple copies of enfuvirtide enhances inhibition of viral replication and cellular transmission in vitro.
PloS one.
2012; 7(7):e41235. doi:
10.1371/journal.pone.0041235. [PMID: 22844444] - Guo-Ping Zhong, Jiang-Ying Chen, Hui-Chang Bi, Xiao-Ling Qin, Chang-Liang Dai, Jing Liu, Xiao Chen, Gui-Xiong Zeng, Zhi-Ying Huang, Min Huang. Determination of HS270, a new histone deacetylase inhibitor, in rat plasma by LC-MS/MS--application to a preclinical pharmacokinetic study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2011 Nov; 879(30):3452-8. doi:
10.1016/j.jchromb.2011.09.023. [PMID: 21983196] - Peggy Gandia, Cecile Arellano, Quentin Chalret du Rieu, Isabelle Lochon, Mario Campone, Jean-Yves Pierga, Muriel Poublanc, Isabelle Hennebelle, Thomas Filleron, Etienne Chatelut, Jean-Pierre Delord. Unexpected high levels of vorinostat when combined with vinorelbine in patients with advanced cancer.
Current clinical pharmacology.
2011 Nov; 6(4):274-9. doi:
10.2174/157488411798375921. [PMID: 22082325] - Mark Andrew Dickson, Dana E Rathkopf, Richard D Carvajal, Steven Grant, John D Roberts, Joel M Reid, Matthew M Ames, Renee M McGovern, Robert A Lefkowitz, Mithat Gonen, Lauren M Cane, Heather J Dials, Gary K Schwartz. A phase I pharmacokinetic study of pulse-dose vorinostat with flavopiridol in solid tumors.
Investigational new drugs.
2011 Oct; 29(5):1004-12. doi:
10.1007/s10637-010-9447-x. [PMID: 20461440] - Yongqing Li, Baoling Liu, Eugene Y Fukudome, Jenifer Lu, Wei Chong, Guang Jin, Zhengcai Liu, George C Velmahos, Marc Demoya, David R King, Hasan B Alam. Identification of citrullinated histone H3 as a potential serum protein biomarker in a lethal model of lipopolysaccharide-induced shock.
Surgery.
2011 Sep; 150(3):442-51. doi:
10.1016/j.surg.2011.07.003. [PMID: 21878229] - Richard E Gilbert, Qingling Huang, Kerri Thai, Suzanne L Advani, Kodie Lee, Darren A Yuen, Kim A Connelly, Andrew Advani. Histone deacetylase inhibition attenuates diabetes-associated kidney growth: potential role for epigenetic modification of the epidermal growth factor receptor.
Kidney international.
2011 Jun; 79(12):1312-21. doi:
10.1038/ki.2011.39. [PMID: 21389970]