Didox (BioDeep_00000016486)

   


代谢物信息卡片


N-3,4-tridhydroxy-benzamide

化学式: C7H7NO4 (169.0375062)
中文名称: 3,4-二羟基苯甲羟肟酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=C(C=C1C(=O)NO)O)O
InChI: InChI=1S/C7H7NO4/c9-5-2-1-4(3-6(5)10)7(11)8-12/h1-3,9-10,12H,(H,8,11)

描述信息

C254 - Anti-Infective Agent > C281 - Antiviral Agent > C1660 - Anti-HIV Agent
C471 - Enzyme Inhibitor > C2150 - Ribonucleotide Reductase Inhibitor
D000970 - Antineoplastic Agents
D004791 - Enzyme Inhibitors

同义名列表

2 个代谢物同义名

Didox; N-3,4-tridhydroxy-benzamide



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Yoichi Osako, Hirofumi Yoshino, Takashi Sakaguchi, Satoshi Sugita, Masaya Yonemori, Masayuki Nakagawa, Hideki Enokida. Potential tumor‑suppressive role of microRNA‑99a‑3p in sunitinib‑resistant renal cell carcinoma cells through the regulation of RRM2. International journal of oncology. 2019 May; 54(5):1759-1770. doi: 10.3892/ijo.2019.4736. [PMID: 30816432]
  • Tian-Yun Jin, Shao-Qiang Li, Cui-Rong Jin, Hao Shan, Rui-Min Wang, Ming-Xing Zhou, Ai-Ling Li, Ling-Yu Li, Shui-Yao Hu, Tao Shen, Lan Xiang. Catecholic Isoquinolines from Portulaca oleracea and Their Anti-inflammatory and β2-Adrenergic Receptor Agonist Activity. Journal of natural products. 2018 04; 81(4):768-777. doi: 10.1021/acs.jnatprod.7b00762. [PMID: 29517238]
  • Vera Go, Yajarayma J Tang-Feldman, Stephanie R Lochhead, G Raymond Lochhead, Cindy Q Yu, Howard L Elford, Mohammed S Inayat, Oliver R Oakley, Claire Pomeroy. Paradoxical response to prophylactic Didox (N-3, 4 trihydroxybenzamide) treatment in murine cytomegalovirus-infected mice. Antiviral therapy. 2011; 16(8):1277-86. doi: 10.3851/imp1893. [PMID: 22155909]
  • J Carmichael, B M Cantwell, K A Mannix, D Veale, H L Elford, R Blackie, D J Kerr, S B Kaye, A L Harris. A phase I and pharmacokinetic study of didox administered by 36 hour infusion. The Cancer Research Campaign Phase I/II Clinical Trials Committee. British journal of cancer. 1990 Mar; 61(3):447-50. doi: 10.1038/bjc.1990.98. [PMID: 2183873]
  • D Veale, J Carmichael, B M Cantwell, H L Elford, R Blackie, D J Kerr, S B Kaye, A L Harris. A phase 1 and pharmacokinetic study of didox: a ribonucleotide reductase inhibitor. British journal of cancer. 1988 Jul; 58(1):70-2. doi: 10.1038/bjc.1988.164. [PMID: 3048353]
  • M Otsuki, C Sakamoto, M Maeda, H Yuu, T Yamasaki, K Okano, S Baba. [The effect of secretin on exocrine and endocrine pancreas. Part I: plasma secretin concentration and pancreatic exocrine secretion after intravenous secretin or intraduodenal HCl and 1-phenyl-1-hydroxy-n-pentane administration (author's transl)]. Nihon Naibunpi Gakkai zasshi. 1978 Oct; 54(10):1116-24. doi: 10.1507/endocrine1927.54.10_1116. [PMID: 31307]
  • A W Mondorf. [Evidence of urinary tubular proteins in inflammatory and toxic kidney damage]. Wiener medizinische Wochenschrift. Supplement. 1975; 27(?):20-3. doi: NULL. [PMID: 5816]