L-Glycero-D-Manno-Heptose (BioDeep_00000015925)
代谢物信息卡片
L-Glycero-D-Manno-Heptose
化学式: C7H14O7 (210.0739494)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(C1C(C(C(C(O1)O)O)O)O)O)O
InChI: InChI=1S/C7H14O7/c8-1-2(9)6-4(11)3(10)5(12)7(13)14-6/h2-13H,1H2/t2-,3-,4-,5-,6+,7?/m0/s1
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Itunuoluwa A Adekoya, Cynthia X Guo, Scott D Gray-Owen, Andrew D Cox, Janelle Sauvageau. d-Glycero-β-d-Manno-Heptose 1-Phosphate and d-Glycero-β-d-Manno-Heptose 1,7-Biphosphate Are Both Innate Immune Agonists.
Journal of immunology (Baltimore, Md. : 1950).
2018 10; 201(8):2385-2391. doi:
10.4049/jimmunol.1801012. [PMID: 30224513] - Jagadesh Mudapaka, Erika Anne Taylor. Cloning and characterization of the Escherichia coli Heptosyltransferase III: Exploring substrate specificity in lipopolysaccharide core biosynthesis.
FEBS letters.
2015 Jun; 589(13):1423-9. doi:
10.1016/j.febslet.2015.04.051. [PMID: 25957775] - Liangbing Wang, Hua Huang, Henry H Nguyen, Karen N Allen, Patrick S Mariano, Debra Dunaway-Mariano. Divergence of biochemical function in the HAD superfamily: D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB).
Biochemistry.
2010 Feb; 49(6):1072-81. doi:
10.1021/bi902018y. [PMID: 20050615] - Hussein Masoud, Malcolm B Perry, Jean-Robert Brisson, Dusan Uhrin, Jianjun Li, James C Richards. Structural elucidation of the novel core oligosaccharide from LPS of Burkholderia cepacia serogroup O4.
Glycobiology.
2009 May; 19(5):462-71. doi:
10.1093/glycob/cwn155. [PMID: 19141607] - Sabine Gronow, Buko Lindner, Helmut Brade, Sven Müller-Loennies. Kdo-(2 --> 8)-Kdo-(2 --> 4)-Kdo but not Kdo-(2 --> 4)-Kdo-(2 --> 4)-Kdo is an acceptor for transfer of L-glycero-alpha-D-manno-heptose by Escherichia coli heptosyltransferase I (WaaC).
Innate immunity.
2009 Feb; 15(1):13-23. doi:
10.1177/1753425908099765. [PMID: 19201821] - Mario A Monteiro, Maria Fortuna-Nevin, John Farley, Viliam Pavliak. Phase-variation of the truncated lipo-oligosaccharide of Neisseria meningitidis NMB phosphoglucomutase isogenic mutant NMB-R6.
Carbohydrate research.
2003 Nov; 338(24):2905-12. doi:
10.1016/j.carres.2003.08.014. [PMID: 14667712] - Martin Månsson, Derek W Hood, E Richard Moxon, Elke K H Schweda. Structural diversity in lipopolysaccharide expression in nontypeable Haemophilus influenzae. Identification of L-glycerol-D-manno-heptose in the outer-core region in three clinical isolates.
European journal of biochemistry.
2003 Feb; 270(4):610-24. doi:
10.1046/j.1432-1033.2003.03399.x. [PMID: 12581201] - Luis Izquierdo, Susana Merino, Nuria Coderch, Miguel Regué, Juan M Tomás. The wavB gene of Vibrio cholerae and the waaE of Klebsiella pneumoniae codify for a beta-1,4-glucosyltransferase involved in the transfer of a glucose residue to the L-glycero-D-manno-heptose I in the lipopolysaccharide inner core.
FEMS microbiology letters.
2002 Nov; 216(2):211-6. doi:
10.1016/s0378-1097(02)01027-3. [PMID: 12435504] - Giles C Shih, Charlene M Kahler, Russell W Carlson, M Mahbubur Rahman, David S Stephens. gmhX, a novel gene required for the incorporation of L-glycero-D-manno-heptose into lipooligosaccharide in Neisseria meningitidis.
Microbiology (Reading, England).
2001 Aug; 147(Pt 8):2367-2377. doi:
10.1099/00221287-147-8-2367. [PMID: 11496013] - K V Antonov, L V Backinowsky, B Grzeszczyk, L Brade, O Holst, A Zamojski. Synthesis and serological characterization of L-glycero-alpha-D-manno-heptopyranose-containing di- and tri-saccharides of the non-reducing terminus of the Escherichia coli K-12 LPS core oligosaccharide.
Carbohydrate research.
1998 Dec; 314(1-2):85-93. doi:
10.1016/s0008-6215(98)00292-4. [PMID: 10230038] - M Süsskind, L Brade, H Brade, O Holst. Identification of a novel heptoglycan of alpha1-->2-linked D-glycero-D-manno-heptopyranose. Chemical and antigenic structure of lipopolysaccharides from Klebsiella pneumoniae ssp. pneumoniae rough strain R20 (O1-:K20-).
The Journal of biological chemistry.
1998 Mar; 273(12):7006-17. doi:
10.1074/jbc.273.12.7006. [PMID: 9507008] - C A Schnaitman, J D Klena. Genetics of lipopolysaccharide biosynthesis in enteric bacteria.
Microbiological reviews.
1993 Sep; 57(3):655-82. doi:
10.1128/mr.57.3.655-682.1993. [PMID: 7504166] - H Masoud, S T Weintraub, R Wang, R Cotter, S C Holt. Investigation of the structure of lipid A from Actinobacillus actinomycetemcomitans strain Y4 and human clinical isolate PO 1021-7.
European journal of biochemistry.
1991 Sep; 200(3):775-81. doi:
10.1111/j.1432-1033.1991.tb16244.x. [PMID: 1915349] - F Nakazawa, T Ito, N Sato, M Sato, E Hoshino. Chemical composition and immunological characterization of polysaccharide antigen from Eubacterium saburreum T18.
Infection and immunity.
1987 Apr; 55(4):871-6. doi:
10.1128/iai.55.4.871-876.1987. [PMID: 2435659]