octamethylpyrophosphoramide (BioDeep_00000001587)

 

Secondary id: BioDeep_00001868309

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


({[bis(dimethylamino)phosphoryl]oxy}(dimethylamino)phosphoryl)dimethylamine

化学式: C8H24N4O3P2 (286.1323574)
中文名称: 八甲磷
谱图信息: 最多检出来源 Homo sapiens(blood) 50%

分子结构信息

SMILES: CN(C)P(=O)(N(C)C)OP(=O)(N(C)C)N(C)C
InChI: InChI=1S/C8H24N4O3P2/c1-9(2)16(13,10(3)4)15-17(14,11(5)6)12(7)8/h1-8H3

描述信息

D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
D010575 - Pesticides > D007306 - Insecticides
D004791 - Enzyme Inhibitors
D016573 - Agrochemicals

同义名列表

6 个代谢物同义名

({[bis(dimethylamino)phosphoryl]oxy}(dimethylamino)phosphoryl)dimethylamine; Octamethyl pyrophosphortetramide; Octamethyl pyrophosphoramide; octamethylpyrophosphoramide; SCHRADAN; Schradan



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • W D Dettbarn, Z P Yang, D Milatovic. Different role of carboxylesterases in toxicity and tolerance to paraoxon and DFP. Chemico-biological interactions. 1999 May; 119-120(?):445-54. doi: 10.1016/s0009-2797(99)00057-5. [PMID: 10421482]
  • A S Ladokhin. Analysis of protein and peptide penetration into membranes by depth-dependent fluorescence quenching: theoretical considerations. Biophysical journal. 1999 Feb; 76(2):946-55. doi: 10.1016/s0006-3495(99)77258-9. [PMID: 9929496]
  • N Saint, E De, S Julien, N Orange, G Molle. Ionophore properties of OmpA of Escherichia coli. Biochimica et biophysica acta. 1993 Jan; 1145(1):119-23. doi: 10.1016/0005-2736(93)90388-g. [PMID: 7678500]
  • J P Chambers, S L Hartgraves, M R Murphy, M J Wayner, N Kumar, J J Valdes. Effects of three reputed carboxylesterase inhibitors upon rat serum esterase activity. Neuroscience and biobehavioral reviews. 1991; 15(1):85-8. doi: 10.1016/s0149-7634(05)80096-x. [PMID: 2052204]
  • R Freudl, H Schwarz, S Kramps, I Hindennach, U Henning. Dihydrofolate reductase (mouse) and beta-galactosidase (Escherichia coli) can be translocated across the plasma membrane of E. coli. The Journal of biological chemistry. 1988 Nov; 263(32):17084-91. doi: 10.1016/s0021-9258(18)37501-x. [PMID: 3141414]
  • M Klose, H Schwarz, S MacIntyre, R Freudl, M L Eschbach, U Henning. Internal deletions in the gene for an Escherichia coli outer membrane protein define an area possibly important for recognition of the outer membrane by this polypeptide. The Journal of biological chemistry. 1988 Sep; 263(26):13291-6. doi: NULL. [PMID: 3047120]
  • M Klose, S MacIntyre, H Schwarz, U Henning. The influence of amino substitutions within the mature part of an Escherichia coli outer membrane protein (OmpA) on assembly of the polypeptide into its membrane. The Journal of biological chemistry. 1988 Sep; 263(26):13297-302. doi: NULL. [PMID: 3047121]
  • L Chen, P C Tai, M S Briggs, L M Gierasch. Protein translocation into Escherichia coli membrane vesicles is inhibited by functional synthetic signal peptides. The Journal of biological chemistry. 1987 Feb; 262(4):1427-9. doi: 10.1016/s0021-9258(19)75650-6. [PMID: 3543005]
  • R Bacallao, E Crooke, K Shiba, W Wickner, K Ito. The secY protein can act post-translationally to promote bacterial protein export. The Journal of biological chemistry. 1986 Sep; 261(27):12907-10. doi: 10.1016/s0021-9258(18)67179-0. [PMID: 3017993]
  • R Freudl, H Schwarz, Y D Stierhof, K Gamon, I Hindennach, U Henning. An outer membrane protein (OmpA) of Escherichia coli K-12 undergoes a conformational change during export. The Journal of biological chemistry. 1986 Aug; 261(24):11355-61. doi: 10.1016/s0021-9258(18)67391-0. [PMID: 2426271]
  • H Vogel, F Jähnig. Models for the structure of outer-membrane proteins of Escherichia coli derived from raman spectroscopy and prediction methods. Journal of molecular biology. 1986 Jul; 190(2):191-9. doi: 10.1016/0022-2836(86)90292-5. [PMID: 3025450]
  • R E Dalbey, W Wickner. Leader peptidase catalyzes the release of exported proteins from the outer surface of the Escherichia coli plasma membrane. The Journal of biological chemistry. 1985 Dec; 260(29):15925-31. doi: 10.1016/s0021-9258(17)36347-0. [PMID: 2999144]
  • N Overbeeke, G Van Scharrenburg, B Lugtenberg. Antigenic relationships between pore proteins of Escherichia coli K12. European journal of biochemistry. 1980 Sep; 110(1):247-54. doi: 10.1111/j.1432-1033.1980.tb04862.x. [PMID: 7002546]
  • L Giuliani, G Carmignani, E Belgrano, P Puppo. Transcatheter arterial embolization in urological tumors: the use of isobutyl-2-cyanoacrylate. The Journal of urology. 1979 May; 121(5):630-4. doi: 10.1016/s0022-5347(17)56913-x. [PMID: 439260]
  • A C Buck. Disorders of micturition in bacterial prostatitis. Proceedings of the Royal Society of Medicine. 1975 Aug; 68(8):508-11. doi: NULL. [PMID: 681]