Fluazifop-butyl (BioDeep_00000001575)

   

human metabolite blood metabolite


代谢物信息卡片


Propanoic acid,2-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]-, butyl ester

化学式: C19H20F3NO4 (383.1344356000001)
中文名称: 吡氟禾草隆
谱图信息: 最多检出来源 Homo sapiens(blood) 98.36%

分子结构信息

SMILES: CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F
InChI: InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3

描述信息

CONFIDENCE standard compound; INTERNAL_ID 1256; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10066; ORIGINAL_PRECURSOR_SCAN_NO 10065
CONFIDENCE standard compound; INTERNAL_ID 1256; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10009; ORIGINAL_PRECURSOR_SCAN_NO 10006
CONFIDENCE standard compound; INTERNAL_ID 1256; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10055; ORIGINAL_PRECURSOR_SCAN_NO 10054
CONFIDENCE standard compound; INTERNAL_ID 1256; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10034; ORIGINAL_PRECURSOR_SCAN_NO 10033
CONFIDENCE standard compound; INTERNAL_ID 1256; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10019; ORIGINAL_PRECURSOR_SCAN_NO 10017
CONFIDENCE standard compound; INTERNAL_ID 1256; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10046; ORIGINAL_PRECURSOR_SCAN_NO 10044
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3093
D010575 - Pesticides > D006540 - Herbicides
D016573 - Agrochemicals

同义名列表

8 个代谢物同义名

Propanoic acid,2-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]-, butyl ester; butyl 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoate; Fluazifop-butyl, (+-)-isomer; Fluazifop-butyl, (S)-isomer; Fluazifop-butyl, (R)-isomer; Fluazifop butyl; FLUAZIFOP-BUTYL; fusilade



数据库引用编号

24 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Carina Lackmann, Mirna Velki, Thomas-Benjamin Seiler, Henner Hollert. Herbicides diuron and fluazifop-p-butyl affect avoidance response and multixenobiotic resistance activity in earthworm Eisenia andrei. Chemosphere. 2018 Nov; 210(?):110-119. doi: 10.1016/j.chemosphere.2018.07.008. [PMID: 29986216]
  • Zhihang Liu, Pingliang Li, Xiaoxue Sun, Fei Zhou, Congjun Yang, Lingxu Li, Hiroshi Matsumoto, Xiaoyong Luo. Fluazifop-P-butyl induced ROS generation with IAA (indole-3-acetic acid) oxidation in Acanthospermum hispidum D.C. Pesticide biochemistry and physiology. 2017 Nov; 143(?):312-318. doi: 10.1016/j.pestbp.2017.10.005. [PMID: 29183607]
  • Yuhong Shang, Congjun Yang, Zhihang Liu, Jiqing Song, Pingliang Li, Lingxu Li, Fei Zhou, Hua Xin, Fanghao Wan, Hiroshi Matsumoto, Xiaoyong Luo. New evidence for primordial action site of Fluazifop-P-butyl on Acanthospermum hispidum seedlings: From the effects on chlorophyll fluorescence characteristics and histological observation. Pesticide biochemistry and physiology. 2017 Oct; 142(?):170-175. doi: 10.1016/j.pestbp.2017.07.006. [PMID: 29107243]
  • Long Du, Weitang Liu, Guohui Yuan, Wenlei Guo, Qi Li, Jinxin Wang. Cross-resistance patterns to ACCase-inhibitors in American sloughgrass (Beckmannia syzigachne Steud.) homozygous for specific ACCase mutations. Pesticide biochemistry and physiology. 2016 Jan; 126(?):42-8. doi: 10.1016/j.pestbp.2015.07.005. [PMID: 26778433]
  • Matheus G Silva, Orivaldo Arf, Paulo E Teodoro. Nitrogen topdressing and application ways of fluazifop-p-butyl + fomesafen in weed control and agronomic performance of common bean. Anais da Academia Brasileira de Ciencias. 2015 Oct; 87(4):2301-7. doi: 10.1590/0001-3765201520140347. [PMID: 26628016]
  • David Olszyk, Matthew Blakeley-Smith, Thomas Pfleeger, E Henry Lee, Milton Plocher. Effects of low levels of herbicides on prairie species of the Willamette Valley, Oregon. Environmental toxicology and chemistry. 2013 Nov; 32(11):2542-51. doi: 10.1002/etc.2331. [PMID: 23881750]
  • Marcin Horbowicz, Cezary Sempruch, Ryszard Kosson, Danuta Koczkodaj, Dajana Walas. Effect of fluazifop-p-butyl treatment on pigments and polyamines level within tissues of non-target maize plants. Pesticide biochemistry and physiology. 2013 Sep; 107(1):78-85. doi: 10.1016/j.pestbp.2013.05.008. [PMID: 25149239]
  • Sufang Fan, Fengzu Zhang, Kailin Deng, Chuanshan Yu, Shaowen Liu, Pengyue Zhao, Canping Pan. Spinach or amaranth contains highest residue of metalaxyl, fluazifop-P-butyl, chlorpyrifos, and lambda-cyhalothrin on six leaf vegetables upon open field application. Journal of agricultural and food chemistry. 2013 Mar; 61(9):2039-44. doi: 10.1021/jf304710u. [PMID: 23387923]
  • Evangelia Chronopoulou, Panagiotis Madesis, Basiliki Asimakopoulou, Dimitrios Platis, Athanasios Tsaftaris, Nikolaos E Labrou. Catalytic and structural diversity of the fluazifop-inducible glutathione transferases from Phaseolus vulgaris. Planta. 2012 Jun; 235(6):1253-69. doi: 10.1007/s00425-011-1572-z. [PMID: 22203322]
  • Robin J Blake, Duncan B Westbury, Ben A Woodcock, Peter Sutton, Simon G Potts. Investigating the phytotoxicity of the graminicide fluazifop-P-butyl against native UK wildflower species. Pest management science. 2012 Mar; 68(3):412-21. doi: 10.1002/ps.2282. [PMID: 21972119]
  • Paul Neve, Stephen Powles. Recurrent selection with reduced herbicide rates results in the rapid evolution of herbicide resistance in Lolium rigidum. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik. 2005 Apr; 110(6):1154-66. doi: 10.1007/s00122-005-1947-2. [PMID: 15756534]
  • L Várnagy, T Varga, I Hlubik, P Budai, E Molnár. Toxicity of the herbicides Flubalex, Fusilade S and Maloran 50 WP to chicken embryos after administration as single compounds or in combination. Acta veterinaria Hungarica. 1996; 44(3):363-76. doi: . [PMID: 9055461]
  • J M Rawlings, J Hilton, K L Trebilcock, B H Woollen, M F Wilks. Effect of dosing vehicle on the dermal absorption of fluazifop-butyl and fomesafen in rats in vivo. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1994 Jul; 23(1):93-100. doi: 10.1006/faat.1994.1084. [PMID: 7958570]
  • J M Rawlings, W M Provan, M F Wilks, P L Batten. Comparison of two methods for determining the toxicokinetics of fluazifop-butyl after intravenous dosing in rats. Human & experimental toxicology. 1994 Feb; 13(2):123-9. doi: 10.1177/096032719401300211. [PMID: 7908809]
  • N W McCracken, P G Blain, F M Williams. Human xenobiotic metabolizing esterases in liver and blood. Biochemical pharmacology. 1993 Oct; 46(7):1125-9. doi: 10.1016/0006-2952(93)90459-a. [PMID: 8216361]
  • B H Woollen. Biological monitoring for pesticide absorption. The Annals of occupational hygiene. 1993 Oct; 37(5):525-40. doi: 10.1093/annhyg/37.5.525. [PMID: 8250473]
  • T R Auton, J D Ramsey, B H Woollen. Modelling dermal pharmacokinetics using in vitro data. Part II. Fluazifop-butyl in man. Human & experimental toxicology. 1993 May; 12(3):207-13. doi: 10.1177/096032719301200303. [PMID: 8100431]
  • T R Auton, J D Ramsey, B H Woollen. Modelling dermal pharmacokinetics using in vitro data. Part I. Fluazifop-butyl in the rat. Human & experimental toxicology. 1993 May; 12(3):199-206. doi: 10.1177/096032719301200302. [PMID: 8100430]
  • N W McCracken, P G Blain, F M Williams. Nature and role of xenobiotic metabolizing esterases in rat liver, lung, skin and blood. Biochemical pharmacology. 1993 Jan; 45(1):31-6. doi: 10.1016/0006-2952(93)90373-5. [PMID: 8424820]
  • J D Ramsey, B H Woollen, T R Auton, P L Batten, J E Leeser. Pharmacokinetics of fluazifop-butyl in human volunteers. II: Dermal dosing. Human & experimental toxicology. 1992 Jul; 11(4):247-54. doi: 10.1177/096032719201100402. [PMID: 1354971]
  • B H Woollen, T B Hart, P L Batten, W J Laird, D S Davies, C T Dollery. Oral pharmacokinetics of fluazifop-butyl in human volunteers. Human & experimental toxicology. 1991 Jan; 10(1):39-43. doi: 10.1177/096032719101000107. [PMID: 1673623]
  • B L Worobey, J B Shields. Determination of fluazifop-butyl and fluazifop acid in soybeans and soybean oil using liquid chromatography with oxidative amperometric detection. Journal - Association of Official Analytical Chemists. 1989 Mar; 72(2):368-71. doi: ". [PMID: 2708288]