Dicrotophos (BioDeep_00000001568)

   

natural product


代谢物信息卡片


Pesticide1_Dicrotophos_C8H16NO5P_(2E)-4-(Dimethylamino)-4-oxo-2-buten-2-yl dimethyl phosphate

化学式: C8H16NO5P (237.0766056)
中文名称: 百治磷
谱图信息: 最多检出来源 Escherichia coli(natural_products) 46.15%

分子结构信息

SMILES: CC(=CC(=O)N(C)C)OP(=O)(OC)OC
InChI: InChI=1S/C8H16NO5P/c1-7(6-8(10)9(2)3)14-15(11,12-4)13-5/h6H,1-5H3/b7-6+

描述信息

C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor
CONFIDENCE standard compound; INTERNAL_ID 1367; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6175; ORIGINAL_PRECURSOR_SCAN_NO 6173
CONFIDENCE standard compound; INTERNAL_ID 1367; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6206; ORIGINAL_PRECURSOR_SCAN_NO 6204
CONFIDENCE standard compound; INTERNAL_ID 1367; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6204; ORIGINAL_PRECURSOR_SCAN_NO 6202
CONFIDENCE standard compound; INTERNAL_ID 1367; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6194; ORIGINAL_PRECURSOR_SCAN_NO 6193
CONFIDENCE standard compound; INTERNAL_ID 1367; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6206; ORIGINAL_PRECURSOR_SCAN_NO 6205
CONFIDENCE standard compound; INTERNAL_ID 1367; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6200; ORIGINAL_PRECURSOR_SCAN_NO 6197

同义名列表

3 个代谢物同义名

Dicrotophos; Pesticide1_Dicrotophos_C8H16NO5P_(2E)-4-(Dimethylamino)-4-oxo-2-buten-2-yl dimethyl phosphate; 3-Hydroxy-N,N-dimethylcrotonamide dimethyl phosphate



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Moneen M Jones, Jessica L Duckworth, Jacqueline Robertson. Toxicity of Bifenthrin and Mixtures of Bifenthrin Plus Acephate, Imidacloprid, Thiamethoxam, or Dicrotophos to Adults of Tarnished Plant Bug (Hemiptera: Miridae). Journal of economic entomology. 2018 04; 111(2):829-835. doi: 10.1093/jee/tox341. [PMID: 29361174]
  • James Heffernan, Pierre Mineau, Ramona Falk, Mark Wickstrom. Combined effect of short-term dehydration and sublethal acute oral dicrotophos exposure confounds the diagnosis of anticholinesterase exposure in common quail (Coturnix coturnix) using plasma cholinesterase activity. Journal of wildlife diseases. 2012 Jul; 48(3):695-706. doi: 10.7589/0090-3558-48.3.695. [PMID: 22740535]
  • John E Casida. The greening of pesticide-environment interactions: some personal observations. Environmental health perspectives. 2012 Apr; 120(4):487-93. doi: 10.1289/ehp.1104405. [PMID: 22472325]
  • Sandra Yucra, Kyle Steenland, Arturo Chung, Fredy Choque, Gustavo F Gonzales. Dialkyl phosphate metabolites of organophosphorus in applicators of agricultural pesticides in Majes - Arequipa (Peru). Journal of occupational medicine and toxicology (London, England). 2006 Dec; 1(?):27. doi: 10.1186/1745-6673-1-27. [PMID: 17177990]
  • F A Tarbah, B Kardel, S Pier, O Temme, T Daldrup. Acute poisoning with phosphamidon: determination of dimethyl phosphate (DMP) as a stable metabolite in a case of organophosphate insecticide intoxication. Journal of analytical toxicology. 2004 Apr; 28(3):198-203. doi: 10.1093/jat/28.3.198. [PMID: 15107151]
  • E A Eliason, D A Potter. Impact of whole-canopy and systemic insecticidal treatments on Callirhytis cornigera (Hymenoptera: Cynipidae) and associated parasitoids on pin oak. Journal of economic entomology. 2000 Feb; 93(1):165-71. doi: 10.1603/0022-0493-93.1.165. [PMID: 14658527]
  • V S Poovala, H Huang, A K Salahudeen. Role of reactive oxygen metabolites in organophosphate-bidrin-induced renal tubular cytotoxicity. Journal of the American Society of Nephrology : JASN. 1999 Aug; 10(8):1746-52. doi: 10.1681/asn.v1081746. [PMID: 10446942]
  • T Markovska, S Koshlukova, A Momchilova, R Pankov, E Yanev. Influence of carbicron (O-[(2-butenoic acid)-N,N-dimethylamide-3-yl] O,O-dimethylphosphate) on some biochemical and biophysical parameters of rat liver membranes. The International journal of biochemistry. 1993 Feb; 25(2):253-7. doi: 10.1016/0020-711x(93)90014-6. [PMID: 8444321]
  • E Yanev, T Markovska, A Momchilova, R Pankov, T Sedloev, K Koumanov. Alterations in rat alveolar surfactant system induced by treatment with carbicron (O-[(2-butenoic acid)-N,N-dimethylamide-3-yl]-O,O-dimethylphosphate). Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. 1992 Nov; 103(3):553-5. doi: 10.1016/0742-8413(92)90180-f. [PMID: 1363304]
  • E F Hill. Sex and storage affect cholinesterase activity in blood plasma of Japanese quail. Journal of wildlife diseases. 1989 Oct; 25(4):580-5. doi: 10.7589/0090-3558-25.4.580. [PMID: 2810558]
  • I C Maxwell, P M Le Quesne. Neuromuscular effects of chronic administration of two organophosphorus insecticides to rats. Neurotoxicology. 1982 Jul; 3(1):1-10. doi: NULL. [PMID: 6890179]
  • E M Lores, D E Bradway, R F Moseman. Organophosphorus pesticide poisonings in humans: determination of residues and metabolites in tissues and urine. Archives of environmental health. 1978 Sep; 33(5):270-6. doi: 10.1080/00039896.1978.10667346. [PMID: 81664]