Degranol (BioDeep_00000015587)

   


代谢物信息卡片


D-Mannitol,1,6-bis[(2-chloroethyl)amino]-1,6-dideoxy-, dihydrochloride (9CI)

化学式: C10H24Cl4N2O4 (376.04901040000004)
中文名称: 甘露醇氮芥
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(CCl)NCC(C(C(C(CNCCCl)O)O)O)O.Cl.Cl
InChI: /m1../s1

描述信息

D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds
D009676 - Noxae > D000477 - Alkylating Agents

同义名列表

2 个代谢物同义名

D-Mannitol,1,6-bis[(2-chloroethyl)amino]-1,6-dideoxy-, dihydrochloride (9CI); Degranol



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • B Stachecki, B Kotelba-Witkowska, J Chmiel. [Effect of cytostatic drugs on the metabolism of incubated human blood platelets]. Acta haematologica Polonica. 1976; 7(1):41-8. doi: NULL. [PMID: 1251675]
  • L F Mal'tseva, N I Moskvitina. [Distribution of degranol in the rat body]. Voprosy onkologii. 1974 Oct; 20(7):75-7. doi: NULL. [PMID: 4409256]
  • L Mosonyi, M Boga, L Cziráki, G Irsy, P Szemere. [Infectious and neoplastic complications in rheumatoid arthritis]. Allergie und Immunologie. 1974 197; 20-21(1):39-43. doi: NULL. [PMID: 4282826]
  • V M Briukhanov. [Effect of degranol on the secretory function of the kidneys]. Farmakologiia i toksikologiia. 1972; 35(1):46-8. doi: NULL. [PMID: 5011516]
  • V G Pashinskiĭ. [Effect of dipin and degranol on the kidney function and water-electrolyte composition of the tumor and blood in rats with sarcoma 45]. Farmakologiia i toksikologiia. 1971 May; 34(3):320-3. doi: NULL. [PMID: 5568693]
  • T N Mikhaĭlova, I B Shternberg, Iu G Kozlova. [Correlation of lymphoid tissue cellular kinetics and factors of non-specific immunobiologic reactivity under the influence of degranol]. Patologicheskaia fiziologiia i eksperimental'naia terapiia. 1970 Nov; 14(6):45-9. doi: NULL. [PMID: 5518615]
  • G Dávid. [Change in the serum leucine aminopeptidase activity during experimental radiation sickness and degranol poisoning]. Radiobiologia, radiotherapia. 1968; 9(1):91-6. doi: NULL. [PMID: 5679642]
  • A Németh, K Kapros, G Baradnay, L Simon. [Studies of the immuno-suppressive effect of degranol, vincaleukoblastine, dibrommannit and mannit-myleran in dogs with kidney homograft]. Orvosi hetilap. 1967 Jul; 108(27):1257-9. doi: NULL. [PMID: 4864765]
  • Z Zsebök. [On the organ transport and the mechanism of excretion of 1,6-bis-chlorethylamine-1,6-D-mannitol-dihydrochloride]. Nuclear-Medizin. 1965; 2(?):35-7. doi: NULL. [PMID: 5888966]
  • F Masszi, U Máté-Wójcińska. Changes of oxyindole acetic acid excretion and the thrombocyte count under the influence of Zitofenton. Neoplasma. 1965; 12(6):629-33. doi: NULL. [PMID: 5324521]
  • Z ZSEBOEK, I TOEROEK, G PETRANYI. [ON ORGAN TRANSPORT AND THE EXCRETION MECHANISM OF 1,6--BIS--(2-CHLOROETHYLAMINO)-1,6--DIDESOXY-D-MANNITOL DIHYDROCHLORIDE]. Strahlentherapie. 1965 Jan; 126(?):111-8. doi: NULL. [PMID: 14266122]
  • Z KOEROES, F HARTAI, U MATE WOJCINSKA, C SELLEI. [DATA ON THE MECHANISM OF ACTION OF DEGRANOL]. Magyar onkologia. 1964 Mar; 8(?):18-23. doi: NULL. [PMID: 14141978]
  • G CSABA, K MOLD, J KOEROESI. [ON THE EFFECT OF TUMOR-INHIBITING AGENTS BOUND TO INACTIVATED HEPARIN ON TISSUE CULTURES]. Neoplasma. 1964; 11(?):345-51. doi: NULL. [PMID: 14200021]
  • E J HIDVEGI, J ARKY, F ANTONI, G J KOTELESS, H BALLWEG. EFFECTS OF KINETIN ANALOGUES ON THE NUCLEIC ACID METABOLISM OF ASCITES TUMOUR CELLS. Acta - Unio Internationalis Contra Cancrum. 1964; 20(?):1037-40. doi: ". [PMID: 14274688]
  • E SZATMARI, T FEHER. [EXAMINATION OF THE STEROID METABOLISM IN HUMAN LEUKEMIA]. Orvosi hetilap. 1963 Sep; 104(?):1692-5. doi: NULL. [PMID: 14054569]
  • M S MAHALEY, J MAHALEY, B WOODHALL. Bioassay of plasma levels of A-139 and mannitol mustard for use in determining blood levels during regional brain cancer perfusions. Cancer chemotherapy reports. 1961 Apr; 11(?):33-40. doi: NULL. [PMID: 13765363]
  • P L HAGONY, M JAKY. Changes in the lipid composition of tumour and hepatic tissues of rats bearing Guerin carcinoma following treatment with the nitrogen mustard degranol. Biochemical pharmacology. 1960 Oct; 5(?):46-52. doi: 10.1016/0006-2952(60)90007-1. [PMID: 13903655]
  • L BAKOS, T VENKEI. [Disappearance of symptoms of granuloma fungoides after mustard mannitol (BCM) therapy]. Orvosi hetilap. 1957 Apr; 98(17):442. doi: ". [PMID: 13452498]