Levan (BioDeep_00000015553)
代谢物信息卡片
Levan
化学式: C18H32O16 (504.1690272)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C1C(C(C(O1)(CO)OCC2C(C(C(O2)(CO)OCC3C(C(C(O3)(CO)O)O)O)O)O)O)O)O
InChI: InChI=1S/C18H32O16/c19-1-7-10(23)14(27)17(5-21,33-7)31-3-9-12(25)15(28)18(6-22,34-9)30-2-8-11(24)13(26)16(29,4-20)32-8/h7-15,19-29H,1-6H2/t7-,8-,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-/m1/s1
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 4522 - Lolium perenne: 10.1046/J.1469-8137.1999.00324.X
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jiao Jiao, Trang Tran-Minh, Anam Nasir, Qinggang Guo, Jörg Stülke, Triinu Visnapuu, Noémie De Zutter, Barbara De Coninck, Wim Van den Ende. Exploring Synergistic Effects of Levan and Levan-Metabolizing Bacillaceae in Promoting Growth and Enhancing Immunity of Tomato and Wheat.
Physiologia plantarum.
2024 May; 176(3):e14325. doi:
10.1111/ppl.14325. [PMID: 38715548] - Mahmoud M Tawfick, Hualing Xie, Chao Zhao, Ping Shao, Mohamed A Farag. Inulin fructans in diet: Role in gut homeostasis, immunity, health outcomes and potential therapeutics.
International journal of biological macromolecules.
2022 May; 208(?):948-961. doi:
10.1016/j.ijbiomac.2022.03.218. [PMID: 35381290] - Wenjing Zeng, Qin Zhang, Gang Feng, Gongliang Liu, Fenglin Wu, Han Shen, Hongwei Shao, Changli Tao. The effect of inulin-type fructans on the intestinal immune function of antibiotic-treated mice.
Applied microbiology and biotechnology.
2022 Apr; 106(8):3265-3278. doi:
10.1007/s00253-022-11896-0. [PMID: 35376973] - Eline Birkeland, Sedegheh Gharagozlian, Hanne L Gulseth, Kåre I Birkeland, Bolette Hartmann, Jens J Holst, René Holst, Anne-Marie Aas. Effects of prebiotics on postprandial GLP-1, GLP-2 and glucose regulation in patients with type 2 diabetes: A randomised, double-blind, placebo-controlled crossover trial.
Diabetic medicine : a journal of the British Diabetic Association.
2021 10; 38(10):e14657. doi:
10.1111/dme.14657. [PMID: 34297363] - Anissa Haddar, Anouar Feriani, Mariem Hamed, Assaad Sila, Semia Ellouz-Chaabouni. Preventive effect of Bacillus mojavensis levan against carbon tetrachloride and cisplatin toxicity: in vivo study.
Environmental science and pollution research international.
2021 Sep; 28(36):50117-50126. doi:
10.1007/s11356-021-14147-3. [PMID: 33948850] - Takuma Nishino, Takanori Goi, Mitsuhiro Morikawa, Kenji Koneri, Satoshi Terada, Makoto Murakami. Fructan Improves Survival and Function of Cryopreserved Rat Islets.
Nutrients.
2021 Aug; 13(9):. doi:
10.3390/nu13092959. [PMID: 34578837] - Charlotte R Hedin, Neil E McCarthy, Petra Louis, Freda M Farquharson, Sara McCartney, Andrew J Stagg, James O Lindsay, Kevin Whelan. Prebiotic fructans have greater impact on luminal microbiology and CD3+ T cells in healthy siblings than patients with Crohn's disease: A pilot study investigating the potential for primary prevention of inflammatory bowel disease.
Clinical nutrition (Edinburgh, Scotland).
2021 08; 40(8):5009-5019. doi:
10.1016/j.clnu.2021.05.033. [PMID: 34364241] - Daniel So, Chu K Yao, Paul A Gill, Naresh Pillai, Peter R Gibson, Jane G Muir. Screening dietary fibres for fermentation characteristics and metabolic profiles using a rapid in vitro approach: implications for irritable bowel syndrome.
The British journal of nutrition.
2021 07; 126(2):208-218. doi:
10.1017/s0007114520003943. [PMID: 33028442] - Mohamed Hefnawy, Abdulrhman Al-Majed, Haitham Alrabiah, Nasser Algrain, Mostafa Mohammed, Yousef Bin Jardan. Rapid and sensitive LC-MS/MS method for the enantioanalysis of verapamil in rat plasma using superficially porous silica isopropyl-cyclofructan 6 chiral stationary phase after SPE: Application to a stereoselective pharmacokinetic study.
Journal of pharmaceutical and biomedical analysis.
2021 Jul; 201(?):114108. doi:
10.1016/j.jpba.2021.114108. [PMID: 33962179] - Simone Luti, Sara Campigli, Francesco Ranaldi, Paolo Paoli, Luigia Pazzagli, Guido Marchi. Lscβ and lscγ, two novel levansucrases of Pseudomonas syringae pv. actinidiae biovar 3, the causal agent of bacterial canker of kiwifruit, show different enzymatic properties.
International journal of biological macromolecules.
2021 May; 179(?):279-291. doi:
10.1016/j.ijbiomac.2021.02.189. [PMID: 33675829] - Silin Wu, Steffen Greiner, Chongjian Ma, Jiaxin Zhong, Xiaojia Huang, Thomas Rausch, Hongbo Zhao. A Fructan Exohydrolase from Maize Degrades Both Inulin and Levan and Co-Exists with 1-Kestotriose in Maize.
International journal of molecular sciences.
2021 May; 22(10):. doi:
10.3390/ijms22105149. [PMID: 34068004] - Shiv Bharadwaj, Sherif Aly El-Kafrawy, Thamir A Alandijany, Leena Hussein Bajrai, Altaf Ahmad Shah, Amit Dubey, Amaresh Kumar Sahoo, Umesh Yadava, Mohammad Amjad Kamal, Esam Ibraheem Azhar, Sang Gu Kang, Vivek Dhar Dwivedi. Structure-Based Identification of Natural Products as SARS-CoV-2 Mpro Antagonist from Echinacea angustifolia Using Computational Approaches.
Viruses.
2021 02; 13(2):. doi:
10.3390/v13020305. [PMID: 33672054] - Bruno P Chumpitazi, Kristi L Hoffman, Daniel P Smith, Ann R McMeans, Salma Musaad, James Versalovic, Joseph F Petrosino, Robert J Shulman. Fructan-sensitive children with irritable bowel syndrome have distinct gut microbiome signatures.
Alimentary pharmacology & therapeutics.
2021 02; 53(4):499-509. doi:
10.1111/apt.16204. [PMID: 33314183] - Rui Cheng, Long Cheng, Yang Zhao, Lei Wang, Shiming Wang, Jianfa Zhang. Biosynthesis and prebiotic activity of a linear levan from a new Paenibacillus isolate.
Applied microbiology and biotechnology.
2021 Jan; 105(2):769-787. doi:
10.1007/s00253-020-11088-8. [PMID: 33404835] - Xiaojia Huang, Wei Luo, Silin Wu, Yuming Long, Rui Li, Fenghua Zheng, Steffen Greiner, Thomas Rausch, Hongbo Zhao. Apoplastic maize fructan exohydrolase Zm-6-FEH displays substrate specificity for levan and is induced by exposure to levan-producing bacteria.
International journal of biological macromolecules.
2020 Nov; 163(?):630-639. doi:
10.1016/j.ijbiomac.2020.06.254. [PMID: 32622772] - Qili Sun, Lixia Zhu, Yixuan Li, Yongsheng Cui, Siliang Jiang, Ning Tao, Hubiao Chen, Zhongzhen Zhao, Jun Xu, Caixia Dong. A novel inulin-type fructan from Asparagus cochinchinensis and its beneficial impact on human intestinal microbiota.
Carbohydrate polymers.
2020 Nov; 247(?):116761. doi:
10.1016/j.carbpol.2020.116761. [PMID: 32829873] - Xue Zhang, Pei Hu, Xiaorui Zhang, Xiaojun Li. Chemical structure elucidation of an inulin-type fructan isolated from Lobelia chinensis lour with anti-obesity activity on diet-induced mice.
Carbohydrate polymers.
2020 Jul; 240(?):116357. doi:
10.1016/j.carbpol.2020.116357. [PMID: 32475601] - Madelon J Logtenberg, Renate Akkerman, Ran An, Gerben D A Hermes, Bart J de Haan, Marijke M Faas, Erwin G Zoetendal, Henk A Schols, Paul de Vos. Fermentation of Chicory Fructo-Oligosaccharides and Native Inulin by Infant Fecal Microbiota Attenuates Pro-Inflammatory Responses in Immature Dendritic Cells in an Infant-Age-Dependent and Fructan-Specific Way.
Molecular nutrition & food research.
2020 07; 64(13):e2000068. doi:
10.1002/mnfr.202000068. [PMID: 32420676] - Kinga Topolska, Marek Bieńko, Agnieszka Filipiak-Florkiewicz, Radosław Piotr Radzki, Ewa Cieślik. The effect of fructan-enriched diet on bone turnover parameters in ovariectomized rats under calcium restriction.
Annals of agricultural and environmental medicine : AAEM.
2020 Jun; 27(2):219-224. doi:
10.26444/aaem/108658. [PMID: 32588596] - Sonia G Sáyago-Ayerdi, Victor M Zamora-Gasga, Koen Venema. Changes in gut microbiota in predigested Hibiscus sabdariffa L calyces and Agave (Agave tequilana weber) fructans assessed in a dynamic in vitro model (TIM-2) of the human colon.
Food research international (Ottawa, Ont.).
2020 06; 132(?):109036. doi:
10.1016/j.foodres.2020.109036. [PMID: 32331660] - Wei Xu, Jiaying Peng, Dawei Ni, Wenli Zhang, Hao Wu, Wanmeng Mu. Preparation, characterization and application of levan/montmorillonite biocomposite and levan/BSA nanoparticle.
Carbohydrate polymers.
2020 Apr; 234(?):115921. doi:
10.1016/j.carbpol.2020.115921. [PMID: 32070541] - K S Swanson, W M de Vos, E C Martens, J A Gilbert, R S Menon, A Soto-Vaca, J Hautvast, P D Meyer, K Borewicz, E E Vaughan, J L Slavin. Effect of fructans, prebiotics and fibres on the human gut microbiome assessed by 16S rRNA-based approaches: a review.
Beneficial microbes.
2020 Mar; 11(2):101-129. doi:
10.3920/bm2019.0082. [PMID: 32073295] - Saeed Bahroudi, Bahareh Shabanpour, Joan Combie, Ali Shabani, Mona Salimi. Levan Exerts Health Benefit Effect through Alteration in Bifidobacteria Population.
Iranian biomedical journal.
2020 01; 24(1):54-9. doi:
10.29252/ibj.24.1.54. [PMID: 31454864] - Paulina Robak, Małgorzata Ożgo, Adam Lepczyński, Agnieszka Herosimczyk, Marcin Barszcz, Marcin Taciak, Jacek Skomiał. Proteome changes in renal cortex and medulla induced by dietary supplementation with inulin-type fructans in growing pigs.
Journal of animal physiology and animal nutrition.
2019 Nov; 103(6):1837-1847. doi:
10.1111/jpn.13170. [PMID: 31368153] - Damien P Belobrajdic, Colin L D Jenkins, Claus T Christophersen, Anthony R Bird. Cereal fructan extracts alter intestinal fermentation to reduce adiposity and increase mineral retention compared to oligofructose.
European journal of nutrition.
2019 Oct; 58(7):2811-2821. doi:
10.1007/s00394-018-1830-y. [PMID: 30284066] - Julie Uerlings, Jérôme Bindelle, Martine Schroyen, Aurore Richel, Geert Bruggeman, Els Willems, Nadia Everaert. Fermentation capacities of fructan- and pectin-rich by-products and purified fractions via an in vitro piglet faecal model.
Journal of the science of food and agriculture.
2019 Oct; 99(13):5720-5733. doi:
10.1002/jsfa.9837. [PMID: 31152455] - Bassem M Salama, Wafaa A Helmy, Tamer I M Ragab, Mamdouh M Ali, Hanan A A Taie, Mona A Esawy. Characterization of a new efficient low molecular weight Bacillus subtilis NRC 16 levansucrase and its levan.
Journal of basic microbiology.
2019 Oct; 59(10):1004-1015. doi:
10.1002/jobm.201900170. [PMID: 31407369] - Onur Kırtel, Eveline Lescrinier, Wim Van den Ende, Ebru Toksoy Öner. Discovery of fructans in Archaea.
Carbohydrate polymers.
2019 Sep; 220(?):149-156. doi:
10.1016/j.carbpol.2019.05.064. [PMID: 31196534] - Erola Astó, Iago Méndez, Maria Rodríguez-Prado, Jordi Cuñé, Jordi Espadaler, Andreu Farran-Codina. Effect of the Degree of Polymerization of Fructans on Ex Vivo Fermented Human Gut Microbiome.
Nutrients.
2019 Jun; 11(6):. doi:
10.3390/nu11061293. [PMID: 31181638] - Tingting Liu, David John Burritt, Indrawati Oey. Understanding the effect of Pulsed Electric Fields on multilayered solid plant foods: Bunching onions (Allium fistulosum) as a model system.
Food research international (Ottawa, Ont.).
2019 06; 120(?):560-567. doi:
10.1016/j.foodres.2018.11.006. [PMID: 31000272] - S Soldi, S Vasileiadis, S Lohner, F Uggeri, E Puglisi, P Molinari, E Donner, C Sieland, T Decsi, M Sailer, S Theis. Prebiotic supplementation over a cold season and during antibiotic treatment specifically modulates the gut microbiota composition of 3-6 year-old children.
Beneficial microbes.
2019 Apr; 10(3):253-263. doi:
10.3920/bm2018.0116. [PMID: 30776899] - Jyoti Singh Jadaun, Lokesh Kumar Narnoliya, Neera Agarwal, Sudhir P Singh. Catalytic biosynthesis of levan and short-chain fructooligosaccharides from sucrose-containing feedstocks by employing the levansucrase from Leuconostoc mesenteroides MTCC10508.
International journal of biological macromolecules.
2019 Apr; 127(?):486-495. doi:
10.1016/j.ijbiomac.2019.01.070. [PMID: 30659880] - Artur Szwengiel, Ghomaka Lydia Nkongha. Influence of acid depolymerization parameters on levan molar mass distribution and its utilization by bacteria.
Carbohydrate polymers.
2019 Feb; 206(?):371-379. doi:
10.1016/j.carbpol.2018.11.029. [PMID: 30553334] - Jan de Vries, Cindy Le Bourgot, Wim Calame, Frédérique Respondek. Effects of β-Fructans Fiber on Bowel Function: A Systematic Review and Meta-Analysis.
Nutrients.
2019 Jan; 11(1):. doi:
10.3390/nu11010091. [PMID: 30621208] - Rosica Valcheva, Petya Koleva, Inés Martínez, Jens Walter, Michael G Gänzle, Levinus A Dieleman. Inulin-type fructans improve active ulcerative colitis associated with microbiota changes and increased short-chain fatty acids levels.
Gut microbes.
2019; 10(3):334-357. doi:
10.1080/19490976.2018.1526583. [PMID: 30395776] - Onur Kirtel, Carmen Menéndez, Maxime Versluys, Wim Van den Ende, Lázaro Hernández, Ebru Toksoy Öner. Levansucrase from Halomonas smyrnensis AAD6T: first halophilic GH-J clan enzyme recombinantly expressed, purified, and characterized.
Applied microbiology and biotechnology.
2018 Nov; 102(21):9207-9220. doi:
10.1007/s00253-018-9311-z. [PMID: 30120521] - Celeste Alexander, Tzu-Wen L Cross, Saravanan Devendran, Franka Neumer, Stephan Theis, Jason M Ridlon, Jan S Suchodolski, Maria R C de Godoy, Kelly S Swanson. Effects of prebiotic inulin-type fructans on blood metabolite and hormone concentrations and faecal microbiota and metabolites in overweight dogs.
The British journal of nutrition.
2018 09; 120(6):711-720. doi:
10.1017/s0007114518001952. [PMID: 30064535] - Kaarel Adamberg, Signe Adamberg, Karin Ernits, Anneli Larionova, Tiia Voor, Madis Jaagura, Triinu Visnapuu, Tiina Alamäe. Composition and metabolism of fecal microbiota from normal and overweight children are differentially affected by melibiose, raffinose and raffinose-derived fructans.
Anaerobe.
2018 Aug; 52(?):100-110. doi:
10.1016/j.anaerobe.2018.06.009. [PMID: 29935270] - Szimonetta Lohner, Viktória Jakobik, Krisztina Mihályi, Sara Soldi, Sotirios Vasileiadis, Stephan Theis, Manuela Sailer, Carolin Sieland, Károly Berényi, Günther Boehm, Tamás Decsi. Inulin-Type Fructan Supplementation of 3- to 6-Year-Old Children Is Associated with Higher Fecal Bifidobacterium Concentrations and Fewer Febrile Episodes Requiring Medical Attention.
The Journal of nutrition.
2018 08; 148(8):1300-1308. doi:
10.1093/jn/nxy120. [PMID: 29982534] - Xin Jian Lei, Yong Min Kim, Jae Hong Park, Dong Heon Baek, Charles Martin Nyachoti, In Ho Kim. Effects of levan-type fructan on growth performance, nutrient digestibility, diarrhoea scores, faecal shedding of total lactic acid bacteria and coliform bacteria, and faecal gas emission in weaning pigs.
Journal of the science of food and agriculture.
2018 Mar; 98(4):1539-1544. doi:
10.1002/jsfa.8625. [PMID: 28802013] - A I Castillo Andrade, C Rivera Bautista, C Godínez Hernández, M A Ruiz Cabrera, C Fuentes Ahumada, E García Chávez, A Grajales Lagunes. Physiometabolic effects of Agave salmiana fructans evaluated in Wistar rats.
International journal of biological macromolecules.
2018 Mar; 108(?):1300-1309. doi:
10.1016/j.ijbiomac.2017.11.043. [PMID: 29138000] - Selina R Cox, Alexis C Prince, Clio E Myers, Peter M Irving, James O Lindsay, Miranda C Lomer, Kevin Whelan. Fermentable Carbohydrates [FODMAPs] Exacerbate Functional Gastrointestinal Symptoms in Patients With Inflammatory Bowel Disease: A Randomised, Double-blind, Placebo-controlled, Cross-over, Re-challenge Trial.
Journal of Crohn's & colitis.
2017 Dec; 11(12):1420-1429. doi:
10.1093/ecco-jcc/jjx073. [PMID: 28525543] - Maria Paz Quezada, Carlos Salinas, Martin Gotteland, Liliana Cardemil. Acemannan and Fructans from Aloe vera (Aloe barbadensis Miller) Plants as Novel Prebiotics.
Journal of agricultural and food chemistry.
2017 Nov; 65(46):10029-10039. doi:
10.1021/acs.jafc.7b04100. [PMID: 29072072] - Raylene A Reimer, Holly J Willis, Jasmine M Tunnicliffe, Heekuk Park, Karen L Madsen, Adriana Soto-Vaca. Inulin-type fructans and whey protein both modulate appetite but only fructans alter gut microbiota in adults with overweight/obesity: A randomized controlled trial.
Molecular nutrition & food research.
2017 11; 61(11):. doi:
10.1002/mnfr.201700484. [PMID: 28730743] - Sandra T Clarke, Stephen P J Brooks, G Douglas Inglis, L Jay Yanke, Judy Green, Nicholas Petronella, D Dan Ramdath, Premysl Bercik, Julia M Green-Johnson, Martin Kalmokoff. Impact of β2-1 fructan on faecal community change: results from a placebo-controlled, randomised, double-blinded, cross-over study in healthy adults.
The British journal of nutrition.
2017 Sep; 118(6):441-453. doi:
10.1017/s0007114517002318. [PMID: 28954640] - Ricardo Closa-Monasterolo, Natalia Ferré, Gemma Castillejo-DeVillasante, Veronica Luque, Mariona Gispert-Llaurado, Marta Zaragoza-Jordana, Stephan Theis, Joaquin Escribano. The use of inulin-type fructans improves stool consistency in constipated children. A randomised clinical trial: pilot study.
International journal of food sciences and nutrition.
2017 Aug; 68(5):587-594. doi:
10.1080/09637486.2016.1263605. [PMID: 27931142] - Francesca Fava, Kieran M Tuohy. Gut microbiota: Inulin regulates endothelial function: a prebiotic smoking gun?.
Nature reviews. Gastroenterology & hepatology.
2017 07; 14(7):392-394. doi:
10.1038/nrgastro.2017.68. [PMID: 28559592] - Yanli Tian, Yuqiang Zhao, Linye Shi, Zhongli Cui, Baishi Hu, Youfu Zhao. Type VI Secretion Systems of Erwinia amylovora Contribute to Bacterial Competition, Virulence, and Exopolysaccharide Production.
Phytopathology.
2017 06; 107(6):654-661. doi:
10.1094/phyto-11-16-0393-r. [PMID: 28421913] - Marília Locatelli Corrêa-Ferreira, Maria Helena Verdan, Francislaine Aparecida Dos Reis Lívero, Larissa Favaretto Galuppo, José Ederaldo Queiroz Telles, Maria Élida Alves Stefanello, Alexandra Acco, Carmen Lúcia de Oliveira Petkowicz. Inulin-type fructan and infusion of Artemisia vulgaris protect the liver against carbon tetrachloride-induced liver injury.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2017 Jan; 24(?):68-76. doi:
10.1016/j.phymed.2016.11.017. [PMID: 28160864] - Iliana Jasso-Padilla, Bertha Juárez-Flores, Gregorio Alvarez-Fuentes, Alejandro De la Cruz-Martínez, José González-Ramírez, Mario Moscosa-Santillán, Marco González-Chávez, Cuauhtemoc Oros-Ovalle, Florian Prell, Peter Czermak, Fidel Martinez-Gutierrez. Effect of prebiotics of Agave salmiana fed to healthy Wistar rats.
Journal of the science of food and agriculture.
2017 Jan; 97(2):556-563. doi:
10.1002/jsfa.7764. [PMID: 27097820] - Ebru Toksoy Öner, Lázaro Hernández, Joan Combie. Review of Levan polysaccharide: From a century of past experiences to future prospects.
Biotechnology advances.
2016 Sep; 34(5):827-844. doi:
10.1016/j.biotechadv.2016.05.002. [PMID: 27178733] - Elena Franco-Robles, Mercedes G López. Agavins Increase Neurotrophic Factors and Decrease Oxidative Stress in the Brains of High-Fat Diet-Induced Obese Mice.
Molecules (Basel, Switzerland).
2016 Aug; 21(8):. doi:
10.3390/molecules21080998. [PMID: 27490526] - Sandra T Clarke, Julia M Green-Johnson, Stephen P J Brooks, D Dan Ramdath, Premysl Bercik, Christian Avila, G Douglas Inglis, Judy Green, L Jay Yanke, L Brent Selinger, Martin Kalmokoff. β2-1 Fructan supplementation alters host immune responses in a manner consistent with increased exposure to microbial components: results from a double-blinded, randomised, cross-over study in healthy adults.
The British journal of nutrition.
2016 May; 115(10):1748-59. doi:
10.1017/s0007114516000908. [PMID: 26987626] - Tzu-Wen Liu, Kimberly D Cephas, Hannah D Holscher, Katherine R Kerr, Heather F Mangian, Kelly A Tappenden, Kelly S Swanson. Nondigestible Fructans Alter Gastrointestinal Barrier Function, Gene Expression, Histomorphology, and the Microbiota Profiles of Diet-Induced Obese C57BL/6J Mice.
The Journal of nutrition.
2016 05; 146(5):949-56. doi:
10.3945/jn.115.227504. [PMID: 27052535] - Susanne L Jensen, Mikkel B Diemer, Maria Lundmark, Flemming H Larsen, Andreas Blennow, Helle K Mogensen, Tom H Nielsen. Levanase from Bacillus subtilis hydrolyses β-2,6 fructosyl bonds in bacterial levans and in grass fructans.
International journal of biological macromolecules.
2016 Apr; 85(?):514-21. doi:
10.1016/j.ijbiomac.2016.01.008. [PMID: 26773563] - Luciano Selistre, Muriel Rabilloud, Pierre Cochat, Vandréa de Souza, Jean Iwaz, Sandrine Lemoine, Françoise Beyerle, Carlos E Poli-de-Figueiredo, Laurence Dubourg. Comparison of the Schwartz and CKD-EPI Equations for Estimating Glomerular Filtration Rate in Children, Adolescents, and Adults: A Retrospective Cross-Sectional Study.
PLoS medicine.
2016 Mar; 13(3):e1001979. doi:
10.1371/journal.pmed.1001979. [PMID: 27023756] - Shamila Weerakoon Abeynayake, Stephen Byrne, Istvan Nagy, Kristina Jonavičienė, Thomas Povl Etzerodt, Birte Boelt, Torben Asp. Changes in Lolium perenne transcriptome during cold acclimation in two genotypes adapted to different climatic conditions.
BMC plant biology.
2015 Oct; 15(?):250. doi:
10.1186/s12870-015-0643-x. [PMID: 26474965] - Yan Yang, Sandra Galle, Minh Hong Anh Le, Ruurd T Zijlstra, Michael G Gänzle. Feed Fermentation with Reuteran- and Levan-Producing Lactobacillus reuteri Reduces Colonization of Weanling Pigs by Enterotoxigenic Escherichia coli.
Applied and environmental microbiology.
2015 Sep; 81(17):5743-52. doi:
10.1128/aem.01525-15. [PMID: 26070673] - Srinivas Kodali, Evgeny Vinogradov, Fiona Lin, Nancy Khoury, Li Hao, Vilo Pavliak, C Hal Jones, Diana Laverde, Johannes Huebner, Kathrin U Jansen, Annaliesa S Anderson, Robert G K Donald. A Vaccine Approach for the Prevention of Infections by Multidrug-resistant Enterococcus faecium.
The Journal of biological chemistry.
2015 Aug; 290(32):19512-26. doi:
10.1074/jbc.m115.655852. [PMID: 26109072] - C Morris, A Lynn, C Neveux, A C Hall, G A Morris. Impact of bread making on fructan chain integrity and effect of fructan enriched breads on breath hydrogen, satiety, energy intake, PYY and ghrelin.
Food & function.
2015 Aug; 6(8):2561-7. doi:
10.1039/c5fo00477b. [PMID: 26113439] - Rapala Srikanth, Gudimalla Siddartha, Chinta H S S Sundhar Reddy, Harish B S, M Janaki Ramaiah, Kiran Babu Uppuluri. Antioxidant and anti-inflammatory levan produced from Acetobacter xylinum NCIM2526 and its statistical optimization.
Carbohydrate polymers.
2015 Jun; 123(?):8-16. doi:
10.1016/j.carbpol.2014.12.079. [PMID: 25843829] - Kaarel Adamberg, Katrin Tomson, Tiina Talve, Ksenia Pudova, Marju Puurand, Triinu Visnapuu, Tiina Alamäe, Signe Adamberg. Levan Enhances Associated Growth of Bacteroides, Escherichia, Streptococcus and Faecalibacterium in Fecal Microbiota.
PloS one.
2015; 10(12):e0144042. doi:
10.1371/journal.pone.0144042. [PMID: 26629816] - Cai-Xia Dong, Li-Jiao Zhang, Rong Xu, Gong Zhang, Ying-Biao Zhou, Xiao-Qiang Han, Ying Zhang, Yuan-Xia Sun. Structural characterization and immunostimulating activity of a levan-type fructan from Curcuma kwangsiensis.
International journal of biological macromolecules.
2015; 77(?):99-104. doi:
10.1016/j.ijbiomac.2015.03.009. [PMID: 25783019] - Hiroaki Matsuhira, Ken-ichi Tamura, Hideto Tamagake, Yutaka Sato, Hiroyuki Anzai, Midori Yoshida. High production of plant type levan in sugar beet transformed with timothy (Phleum pratense) 6-SFT genes.
Journal of biotechnology.
2014 Dec; 192 Pt A(?):215-22. doi:
10.1016/j.jbiotec.2014.09.025. [PMID: 25305472] - María Isabel García-Vieyra, Alicia Del Real, Mercedes G López. Agave fructans: their effect on mineral absorption and bone mineral content.
Journal of medicinal food.
2014 Nov; 17(11):1247-55. doi:
10.1089/jmf.2013.0137. [PMID: 25069021] - K A Barry, D C Hernot, J Van Loo, G C Fahey, M R C de Godoy. Fructan supplementation of senior cats affects stool metabolite concentrations and fecal microbiota concentrations, but not nitrogen partitioning in excreta.
Journal of animal science.
2014 Nov; 92(11):4964-71. doi:
10.2527/jas.2013-7510. [PMID: 25349345] - Emanuel Axente, Felix Sima, Livia Elena Sima, Merve Erginer, Mehmet S Eroglu, Natalia Serban, Carmen Ristoscu, Stefana M Petrescu, Ebru Toksoy Oner, Ion N Mihailescu. Combinatorial MAPLE gradient thin film assemblies signalling to human osteoblasts.
Biofabrication.
2014 Sep; 6(3):035010. doi:
10.1088/1758-5082/6/3/035010. [PMID: 24867882] - Akiko Ogawa, Shinya Mizui, Yasuhito Chida, Masafumi Shimizu, Satoshi Terada, Takeshi Ohura, Kyo-Ichi Kobayashi, Saori Yasukawa, Nobuyuki Moriyama. Rakkyo fructan as a cryoprotectant for serum-free cryopreservation of mammalian cells.
Journal of bioscience and bioengineering.
2014 Jul; 118(1):101-6. doi:
10.1016/j.jbiosc.2013.12.010. [PMID: 24485744] - Leonie M Vogt, Diederick Meyer, Gerdie Pullens, Marijke M Faas, Koen Venema, Uttara Ramasamy, Henk A Schols, Paul de Vos. Toll-like receptor 2 activation by β2→1-fructans protects barrier function of T84 human intestinal epithelial cells in a chain length-dependent manner.
The Journal of nutrition.
2014 Jul; 144(7):1002-8. doi:
10.3945/jn.114.191643. [PMID: 24790027] - Jin sun Oh, Seung Ri Lee, Keum Taek Hwang, Geun Eog Ji. The anti-obesity effects of the dietary combination of fermented red ginseng with levan in high fat diet mouse model.
Phytotherapy research : PTR.
2014 Apr; 28(4):617-22. doi:
10.1002/ptr.5042. [PMID: 23873605] - Shaunak Khandekar, Abhishek Srivastava, Daniel Pletzer, Antje Stahl, Matthias S Ullrich. The conserved upstream region of lscB/C determines expression of different levansucrase genes in plant pathogen Pseudomonas syringae.
BMC microbiology.
2014 Mar; 14(?):79. doi:
10.1186/1471-2180-14-79. [PMID: 24670199] - XiaoLi Shi, Xiao Lin, XiangWei Zheng, Yi Feng, Lan Shen. Injectable long-acting systems for Radix Ophiopogonis polysaccharide based on mono-PEGylation and in situ formation of a PLGA depot.
International journal of nanomedicine.
2014; 9(?):5555-63. doi:
10.2147/ijn.s71819. [PMID: 25489243] - Margarita S Dodevska, Brizita I Djordjevic, Sladjana S Sobajic, Ivanka D Miletic, Predrag B Djordjevic, Vesna S Dimitrijevic-Sreckovic. Characterisation of dietary fibre components in cereals and legumes used in Serbian diet.
Food chemistry.
2013 Dec; 141(3):1624-9. doi:
10.1016/j.foodchem.2013.05.078. [PMID: 23870869] - J Li, I H Kim. Effects of levan-type fructan supplementation on growth performance, digestibility, blood profile, fecal microbiota, and immune responses after lipopolysaccharide challenge in growing pigs.
Journal of animal science.
2013 Nov; 91(11):5336-43. doi:
10.2527/jas.2013-6665. [PMID: 24045486] - P Y Zhao, J P Wang, I H Kim. Effect of dietary levan fructan supplementation on growth performance, meat quality, relative organ weight, cecal microflora, and excreta noxious gas emission in broilers.
Journal of animal science.
2013 Nov; 91(11):5287-93. doi:
10.2527/jas.2012-5464. [PMID: 24045474] - P Y Zhao, J P Wang, I H Kim. Evaluation of dietary fructan supplementation on growth performance, nutrient digestibility, meat quality, fecal microbial flora, and fecal noxious gas emission in finishing pigs.
Journal of animal science.
2013 Nov; 91(11):5280-6. doi:
10.2527/jas.2012-5393. [PMID: 24045483] - Ana Laura Márquez-Aguirre, Rosa Maria Camacho-Ruiz, Myriam Arriaga-Alba, Eduardo Padilla-Camberos, Manuel Reinhart Kirchmayr, José Luis Blasco, Marisela González-Avila. Effects of Agave tequilana fructans with different degree of polymerization profiles on the body weight, blood lipids and count of fecal Lactobacilli/Bifidobacteria in obese mice.
Food & function.
2013 Aug; 4(8):1237-44. doi:
10.1039/c3fo60083a. [PMID: 23759883] - Sabine Zitta, Walter Schrabmair, Gilbert Reibnegger, Andreas Meinitzer, Doris Wagner, Willibald Estelberger, Alexander R Rosenkranz. Glomerular filtration rate (GFR) determination via individual kinetics of the inulin-like polyfructosan sinistrin versus creatinine-based population-derived regression formulae.
BMC nephrology.
2013 Jul; 14(?):159. doi:
10.1186/1471-2369-14-159. [PMID: 23876053] - Imen Dahech, Bahira Harrabi, Khaled Hamden, Abdelfattah Feki, Hafedh Mejdoub, Hafedh Belghith, Karima Srih Belghith. Antioxidant effect of nondigestible levan and its impact on cardiovascular disease and atherosclerosis.
International journal of biological macromolecules.
2013 Jul; 58(?):281-6. doi:
10.1016/j.ijbiomac.2013.04.058. [PMID: 23624165] - Leonie Vogt, Uttara Ramasamy, Diederick Meyer, Gerdie Pullens, Koen Venema, Marijke M Faas, Henk A Schols, Paul de Vos. Immune modulation by different types of β2→1-fructans is toll-like receptor dependent.
PloS one.
2013; 8(7):e68367. doi:
10.1371/journal.pone.0068367. [PMID: 23861894] - Jaco Franken, Bianca A Brandt, Siew L Tai, Florian F Bauer. Biosynthesis of levan, a bacterial extracellular polysaccharide, in the yeast Saccharomyces cerevisiae.
PloS one.
2013; 8(10):e77499. doi:
10.1371/journal.pone.0077499. [PMID: 24147008] - Amy R Lomax, Lydia V Y Cheung, Kieran M Tuohy, Paul S Noakes, Elizabeth A Miles, Philip C Calder. β2-1 Fructans have a bifidogenic effect in healthy middle-aged human subjects but do not alter immune responses examined in the absence of an in vivo immune challenge: results from a randomised controlled trial.
The British journal of nutrition.
2012 Nov; 108(10):1818-28. doi:
10.1017/s0007114511007276. [PMID: 22244014] - L B Bindels, P Porporato, E M Dewulf, J Verrax, A M Neyrinck, J C Martin, K P Scott, P Buc Calderon, O Feron, G G Muccioli, P Sonveaux, P D Cani, N M Delzenne. Gut microbiota-derived propionate reduces cancer cell proliferation in the liver.
British journal of cancer.
2012 Oct; 107(8):1337-44. doi:
10.1038/bjc.2012.409. [PMID: 22976799] - Karima Srih Belghith, Imen Dahech, Khaled Hamden, Abdelfattah Feki, Hafedh Mejdoub, Hafedh Belghith. Hypolipidemic effect of diet supplementation with bacterial levan in cholesterol-fed rats.
International journal of biological macromolecules.
2012 May; 50(4):1070-4. doi:
10.1016/j.ijbiomac.2012.02.024. [PMID: 22433476] - Juan A Rendón-Huerta, Bertha Juárez-Flores, Juan M Pinos-Rodríguez, J Rogelio Aguirre-Rivera, Rosa E Delgado-Portales. Effects of different sources of fructans on body weight, blood metabolites and fecal bacteria in normal and obese non-diabetic and diabetic rats.
Plant foods for human nutrition (Dordrecht, Netherlands).
2012 Mar; 67(1):64-70. doi:
10.1007/s11130-011-0266-9. [PMID: 22210166] - Puthanapura M Chandrashekar, Yeldur P Venkatesh. Fructans from aged garlic extract produce a delayed immunoadjuvant response to ovalbumin antigen in BALB/c mice.
Immunopharmacology and immunotoxicology.
2012 Feb; 34(1):174-80. doi:
10.3109/08923973.2011.584066. [PMID: 21631395] - Imen Dahech, Karima Srih Belghith, Khaled Hamden, Abdelfattah Feki, Hafedh Belghith, Hafedh Mejdoub. Oral administration of levan polysaccharide reduces the alloxan-induced oxidative stress in rats.
International journal of biological macromolecules.
2011 Dec; 49(5):942-7. doi:
10.1016/j.ijbiomac.2011.08.011. [PMID: 21925206] - Imen Dahech, Karima Srih Belghith, Khaled Hamden, Abdelfattah Feki, Hafedh Belghith, Hafedh Mejdoub. Antidiabetic activity of levan polysaccharide in alloxan-induced diabetic rats.
International journal of biological macromolecules.
2011 Nov; 49(4):742-6. doi:
10.1016/j.ijbiomac.2011.07.007. [PMID: 21782842] - Felix Sima, Esra Cansever Mutlu, Mehmet S Eroglu, Livia E Sima, Natalia Serban, Carmen Ristoscu, Stefana M Petrescu, Ebru Toksoy Oner, Ion N Mihailescu. Levan nanostructured thin films by MAPLE assembling.
Biomacromolecules.
2011 Jun; 12(6):2251-6. doi:
10.1021/bm200340b. [PMID: 21520921] - Alexander Banguela, Juan G Arrieta, Raisa Rodríguez, Luis E Trujillo, Carmen Menéndez, Lázaro Hernández. High levan accumulation in transgenic tobacco plants expressing the Gluconacetobacter diazotrophicus levansucrase gene.
Journal of biotechnology.
2011 Jun; 154(1):93-8. doi:
10.1016/j.jbiotec.2011.04.007. [PMID: 21540065] - Nana K A Bonsu, C Shanthi Johnson, Katherine M McLeod. Can dietary fructans lower serum glucose?.
Journal of diabetes.
2011 Mar; 3(1):58-66. doi:
10.1111/j.1753-0407.2010.00099.x. [PMID: 21040500] - Jerzy Juśkiewicz, Zenon Zduńczyk, Ewa Zary-Sikorska, Bogusław Król, Joanna Milala, Adam Jurgoński. Effect of the dietary polyphenolic fraction of chicory root, peel, seed and leaf extracts on caecal fermentation and blood parameters in rats fed diets containing prebiotic fructans.
The British journal of nutrition.
2011 Mar; 105(5):710-20. doi:
10.1017/s0007114510004344. [PMID: 21134333] - Jerzy Juśkiewicz, Ewa Zary-Sikorska, Zenon Zduńczyk, Bogusław Król, Adam Jurgoński. Physiological effects of chicory root preparations with various levels of fructan and polyphenolic fractions in diets for rats.
Archives of animal nutrition.
2011 Feb; 65(1):74-87. doi:
10.1080/1745039x.2010.533542. [PMID: 21452615] - Wim Van den Ende, Marlies Coopman, Stefan Clerens, Rudy Vergauwen, Katrien Le Roy, Willem Lammens, André Van Laere. Unexpected presence of graminan- and levan-type fructans in the evergreen frost-hardy eudicot Pachysandra terminalis (Buxaceae): purification, cloning, and functional analysis of a 6-SST/6-SFT enzyme.
Plant physiology.
2011 Jan; 155(1):603-14. doi:
10.1104/pp.110.162222. [PMID: 21037113] - F J Alarcon-Aguilar, A Fortis-Barrera, S Angeles-Mejia, T R Banderas-Dorantes, E I Jasso-Villagomez, J C Almanza-Perez, G Blancas-Flores, A Zamilpa, M Diaz-Flores, R Roman-Ramos. Anti-inflammatory and antioxidant effects of a hypoglycemic fructan fraction from Psacalium peltatum (H.B.K.) Cass. in streptozotocin-induced diabetes mice.
Journal of ethnopharmacology.
2010 Nov; 132(2):400-7. doi:
10.1016/j.jep.2010.08.003. [PMID: 20713141] - Laurence Dubourg, Aoumeur Hadj-Aïssa, Bernard Ferrier. Adaptation of an enzymatic polyfructosan assay to clinical practice.
Analytical biochemistry.
2010 Oct; 405(2):266-8. doi:
10.1016/j.ab.2010.06.016. [PMID: 20541517] - Mónica Ordax, Ester Marco-Noales, María M López, Elena G Biosca. Exopolysaccharides favor the survival of Erwinia amylovora under copper stress through different strategies.
Research in microbiology.
2010 Sep; 161(7):549-55. doi:
10.1016/j.resmic.2010.05.003. [PMID: 20546893] - Xiao Lin, Zhuojun Wang, Guilan Sun, Lan Shen, Desheng Xu, Yi Feng. A sensitive and specific HPGPC-FD method for the study of pharmacokinetics and tissue distribution of Radix Ophiopogonis polysaccharide in rats.
Biomedical chromatography : BMC.
2010 Aug; 24(8):820-5. doi:
10.1002/bmc.1369. [PMID: 20020416] - Jun Liu, Jianguang Luo, Yi Sun, Hong Ye, Zhaoxin Lu, Xiaoxiong Zeng. A simple method for the simultaneous decoloration and deproteinization of crude levan extract from Paenibacillus polymyxa EJS-3 by macroporous resin.
Bioresource technology.
2010 Aug; 101(15):6077-83. doi:
10.1016/j.biortech.2010.03.019. [PMID: 20346649]
