N-propargylglycine (BioDeep_00000015465)
代谢物信息卡片
(2S)-2-Amino-4-pentynoic acid
化学式: C5H7NO2 (113.0477)
中文名称: L-C-炔丙基甘氨酸, L-炔丙基甘氨酸
谱图信息:
最多检出来源 Homo sapiens(blood) 28.42%
分子结构信息
SMILES: C#CCC(C(=O)O)N
InChI: InChI=1S/C5H7NO2/c1-2-3-4(6)5(7)8/h1,4H,3,6H2,(H,7,8)/t4-/m0/s1
描述信息
A non-proteinogenic L-alpha-amino acid that is L-alanine in which one of the methyl hydrogens has been replaced by an ethynyl group. It causes the irreversible inactivation of gamma-cystathionase (also known as cystathionine gamma-lyase) and is used as an affinity labeling reagent for gamma-cystathionase and other enzymes.
D004791 - Enzyme Inhibitors
(S)-2-Aminopent-4-ynoic acid is a synthetic amino acid. (S)-2-Aminopent-4-ynoic acid can be used in synthesis of folate-conjugates and corresponding metal-chelate complexes[1]. (S)-2-Aminopent-4-ynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:43797
- KEGG: C22138
- PubChem: 168091
- ChEMBL: CHEMBL50483
- CAS: 198774-27-5
- CAS: 23235-01-0
- MetaboLights: MTBLC43797
- PubChem: 405226329
- PDB-CCD: LPH
- medchemexpress: HY-W006064
- LOTUS: LTS0058511
- wikidata: Q27270926
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Andreia Mara Moreira, Samuel Amorin Grisote, Heloisa Della Colleta Francescato, Terezila Machado Coimbra, Lucila Leico Kagohara Elias, José Antunes-Rodrigues, Silvia Graciela Ruginsk. Effects of endogenous H2S production inhibition on the homeostatic responses induced by acute high-salt diet consumption.
Molecular and cellular biochemistry.
2021 Feb; 476(2):715-725. doi:
10.1007/s11010-020-03938-w. [PMID: 33128215] - Xiangxue Lu, Shixiang Wang, Sujuan Feng, Han Li. CSE/H2S system alleviates uremic accelerated atherosclerosis by regulating TGF-β/Smad3 pathway in 5/6 nephrectomy ApoE-/- mice.
BMC nephrology.
2020 12; 21(1):527. doi:
10.1186/s12882-020-02183-z. [PMID: 33276745] - Bec J Roldan, Andrea O Pajarillo, Jacob D Greenberg, Joyce E Karlinsey, Mauricio Cafiero, Elaine R Frawley, Larryn W Peterson. Propargylglycine-based antimicrobial compounds are targets of TolC-dependent efflux systems in Escherichia coli.
Bioorganic & medicinal chemistry letters.
2020 01; 30(2):126875. doi:
10.1016/j.bmcl.2019.126875. [PMID: 31836438] - Srijanani Kannan, Sri Rahavi Boovarahan, Jeyashri Rengaraju, Priyanka Prem, Gino A Kurian. Attenuation of cardiac ischemia-reperfusion injury by sodium thiosulfate is partially dependent on the effect of cystathione beta synthase in the myocardium.
Cell biochemistry and biophysics.
2019 Sep; 77(3):261-272. doi:
10.1007/s12013-019-00871-8. [PMID: 31065867] - Mai M Helmy, Maged W Helmy, Mahmoud M El-Mas. Upregulation of cystathionine-γ-lyase/hydrogen sulfide pathway underlies the celecoxib counteraction of cyclosporine-induced hypertension and renal insult in rats.
Prostaglandins & other lipid mediators.
2019 04; 141(?):1-10. doi:
10.1016/j.prostaglandins.2019.01.001. [PMID: 30658157] - Renfei Luo, Shan Hu, Qiaojuan Liu, Mengke Han, Feifei Wang, Miaojuan Qiu, Suchun Li, Xiaosa Li, Tianxin Yang, Xiaodong Fu, Weidong Wang, Chunling Li. Hydrogen sulfide upregulates renal AQP-2 protein expression and promotes urine concentration.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2019 01; 33(1):469-483. doi:
10.1096/fj.201800436r. [PMID: 30036087] - Renato N Soriano, Sara P Braga, Jéssica S C Breder, Marcelo E Batalhao, Gabriela R Oliveira-Pelegrin, Luiz Fernando R Ferreira, Maria José A Rocha, Evelin C Carnio, Luiz G S Branco. Endogenous peripheral hydrogen sulfide is propyretic: its permissive role in brown adipose tissue thermogenesis in rats.
Experimental physiology.
2018 03; 103(3):397-407. doi:
10.1113/ep086775. [PMID: 29210120] - Hongming Guo, Heng Zhou, Jing Zhang, Wenxue Guan, Sheng Xu, Wenbiao Shen, Guohua Xu, Yanjie Xie, Christine Helen Foyer. l-cysteine desulfhydrase-related H2 S production is involved in OsSE5-promoted ammonium tolerance in roots of Oryza sativa.
Plant, cell & environment.
2017 Sep; 40(9):1777-1790. doi:
10.1111/pce.12982. [PMID: 28474399] - Chao Wang, Juan Han, Dong-Jian Li, Zhen Yang, Lin Zhang. Protective effects of hydrogen sulfide on portal hypertensive vasculopathy in rabbits by activating AKT-NF-κB pathway.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.
2017 Jun; 37(3):348-351. doi:
10.1007/s11596-017-1738-4. [PMID: 28585141] - Bo Tang, Lan Ma, Xiaoyi Yao, Gang Tan, Peng Han, Tianchi Yu, Bing Liu, Xueying Sun. Hydrogen sulfide ameliorates acute lung injury induced by infrarenal aortic cross-clamping by inhibiting inflammation and angiopoietin 2 release.
Journal of vascular surgery.
2017 02; 65(2):501-508.e1. doi:
10.1016/j.jvs.2015.10.010. [PMID: 26781077] - Xie-Feng Ye, Yanfeng Xue, Tianxiao Ling, Yong Wang, Xiao-Na Yu, Changxin Cheng, Guosheng Feng, Liangbin Hu, Zhiqi Shi, Jian Chen. Cinnamaldehyde Ameliorates Cadmium-Inhibited Root Elongation in Tobacco Seedlings via Decreasing Endogenous Hydrogen Sulfide Production.
Molecules (Basel, Switzerland).
2016 Dec; 22(1):. doi:
10.3390/molecules22010015. [PMID: 28029133] - M Stojanovic, V Zivkovic, I Srejovic, V Jakovljevic, N Jeremic, D Djuric. The role of hydrogen sulfide in homocysteine-induced cardiodynamic effects and oxidative stress markers in the isolated rat heart.
Physiology international.
2016 Dec; 103(4):428-438. doi:
10.1556/2060.103.2016.4.3. [PMID: 28229626] - Yan Lin, Yulong Chen, Ninghong Zhu, Sihai Zhao, Jianglin Fan, Enqi Liu. Hydrogen sulfide inhibits development of atherosclerosis through up-regulating protein S-nitrosylation.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2016 Oct; 83(?):466-476. doi:
10.1016/j.biopha.2016.07.003. [PMID: 27427853] - Yoshitaka Yasuda, Guo-Gang Feng, Jiazheng Li, Emi Nakamura, Hisaki Hayashi, Motohiko Sato, Yoshihiro Fujiwara, Hiroyuki Kinoshita. High oxygen modifies vasodilator effect of cysteine via enhanced oxidative stress and thromboxane production in the rat mesenteric artery.
Pflugers Archiv : European journal of physiology.
2016 09; 468(9):1555-64. doi:
10.1007/s00424-016-1857-y. [PMID: 27389323] - Shaimaa S El-Sayed, Mohamed N M Zakaria, Rasha H Abdel-Ghany, Abdel A Abdel-Rahman. Cystathionine-γ lyase-derived hydrogen sulfide mediates the cardiovascular protective effects of moxonidine in diabetic rats.
European journal of pharmacology.
2016 Jul; 783(?):73-84. doi:
10.1016/j.ejphar.2016.04.054. [PMID: 27138707] - Qien Li, Zhaofeng Wang, Yanning Zhao, Xiaochen Zhang, Shuaijun Zhang, Letao Bo, Yao Wang, Yingfeng Ding, Lizhe An. Putrescine protects hulless barley from damage due to UV-B stress via H2S- and H2O2-mediated signaling pathways.
Plant cell reports.
2016 May; 35(5):1155-68. doi:
10.1007/s00299-016-1952-8. [PMID: 26910861] - Xin-hai Cen, Zhi-xiang Zhang, Tao Wang, Yan-sha Wang, Ying-lei Ji, Jun Yan, Zhen-yong Gu. [The Role of Hydrogen Sulfide in Acute Liver Injury Induced by Traumatic Stress in Rats].
Fa yi xue za zhi.
2016 Apr; 32(2):81-5. doi:
. [PMID: 27501675] - Francisco J Luna-Vázquez, César Ibarra-Alvarado, Alejandra Rojas-Molina, Antonio Romo-Mancillas, Fabián H López-Vallejo, Mariana Solís-Gutiérrez, Juana I Rojas-Molina, Fausto Rivero-Cruz. Role of Nitric Oxide and Hydrogen Sulfide in the Vasodilator Effect of Ursolic Acid and Uvaol from Black Cherry Prunus serotina Fruits.
Molecules (Basel, Switzerland).
2016 Jan; 21(1):78. doi:
10.3390/molecules21010078. [PMID: 26771591] - Nynke R Oosterhuis, Anne-Roos S Frenay, Sebastiaan Wesseling, Pauline M Snijder, Gisela G Slaats, Saleh Yazdani, Bernadette O Fernandez, Martin Feelisch, Rachel H Giles, Marianne C Verhaar, Jaap A Joles, Harry van Goor. DL-propargylglycine reduces blood pressure and renal injury but increases kidney weight in angiotensin-II infused rats.
Nitric oxide : biology and chemistry.
2015 Sep; 49(?):56-66. doi:
10.1016/j.niox.2015.07.001. [PMID: 26192363] - Sang Jun Han, Jee In Kim, Jeen-Woo Park, Kwon Moo Park. Hydrogen sulfide accelerates the recovery of kidney tubules after renal ischemia/reperfusion injury.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2015 Sep; 30(9):1497-506. doi:
10.1093/ndt/gfv226. [PMID: 26142397] - Hui-Ning Fan, Ni-Wei Chen, Wei-Lin Shen, Xiang-Yun Zhao, Jing Zhang. Endogenous hydrogen sulfide is associated with angiotensin II type 1 receptor in a rat model of carbon tetrachloride-induced hepatic fibrosis.
Molecular medicine reports.
2015 Sep; 12(3):3351-3358. doi:
10.3892/mmr.2015.3873. [PMID: 26034979] - B Han, Z G Zhao, L M Zhang, S G Li, C Y Niu. Hydrogen sulfide in posthemorrhagic shock mesenteric lymph drainage alleviates kidney injury in rats.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
2015 Jul; 48(7):622-8. doi:
10.1590/1414-431x20154057. [PMID: 25945746] - Patrycja Bronowicka-Adamska, Jacek Zagajewski, Maria Wróbel. An application of RP-HPLC for determination of the activity of cystathionine β-synthase and γ-cystathionase in tissue homogenates.
Nitric oxide : biology and chemistry.
2015 Apr; 46(?):186-91. doi:
10.1016/j.niox.2014.09.159. [PMID: 25307719] - Chun-Yan Rao, Lan-Ying Fu, Chang-Lun Hu, Dai-Xing Chen, Tian Gan, Yi-Cheng Wang, Xiao-Yan Zhao. H2S mitigates severe acute pancreatitis through the PI3K/AKT-NF-κB pathway in vivo.
World journal of gastroenterology.
2015 Apr; 21(15):4555-63. doi:
10.3748/wjg.v21.i15.4555. [PMID: 25914464] - Sebastiaan Wesseling, Joost O Fledderus, Marianne C Verhaar, Jaap A Joles. Beneficial effects of diminished production of hydrogen sulfide or carbon monoxide on hypertension and renal injury induced by NO withdrawal.
British journal of pharmacology.
2015 Mar; 172(6):1607-19. doi:
10.1111/bph.12674. [PMID: 24597655] - Xing Liu, Dongming Ma, Shuzhan Zheng, Kelan Zha, Jian Feng, Yihua Cai, Feng Jiang, Jiafu Li, Zhongcai Fan. The roles of nitric oxide and hydrogen sulfide in the anti-atherosclerotic effect of atorvastatin.
Journal of cardiovascular medicine (Hagerstown, Md.).
2015 Jan; 16(1):22-8. doi:
10.2459/jcm.0000000000000012. [PMID: 24933195] - Ye Liu, Huichen Zhao, Ye Qiang, Guanfang Qian, Shengxia Lu, Jicui Chen, Xiangdong Wang, Qingbo Guan, Yuantao Liu, Yuqin Fu. Effects of hydrogen sulfide on high glucose-induced glomerular podocyte injury in mice.
International journal of clinical and experimental pathology.
2015; 8(6):6814-20. doi:
". [PMID: 26261567] - Seldag Bekpinar, Yesim Unlucerci, Mujdat Uysal, Figen Gurdol. Propargylglycine aggravates liver damage in LPS-treated rats: Possible relation of nitrosative stress with the inhibition of H2S formation.
Pharmacological reports : PR.
2014 Oct; 66(5):897-901. doi:
10.1016/j.pharep.2014.05.014. [PMID: 25149998] - Congsheng Li, Zeng Guo, Birong Guo, Yangjing Xie, Jing Yang, Ailing Wang. Inhibition of the endogenous CSE/H₂S system contributes to hypoxia and serum deprivation-induced apoptosis in mesenchymal stem cells.
Molecular medicine reports.
2014 Jun; 9(6):2467-72. doi:
10.3892/mmr.2014.2111. [PMID: 24699897] - M E Velasco-Xolalpa, P Barragán-Iglesias, J E Roa-Coria, B Godínez-Chaparro, F J Flores-Murrieta, J E Torres-López, C I Araiza-Saldaña, A Navarrete, H I Rocha-González. Role of hydrogen sulfide in the pain processing of non-diabetic and diabetic rats.
Neuroscience.
2013 Oct; 250(?):786-97. doi:
10.1016/j.neuroscience.2013.06.053. [PMID: 23830907] - Keqing Wang, Shakil Ahmad, Meng Cai, Jillian Rennie, Takeshi Fujisawa, Fatima Crispi, James Baily, Mark R Miller, Melissa Cudmore, Patrick W F Hadoke, Rui Wang, Eduard Gratacós, Irina A Buhimschi, Catalin S Buhimschi, Asif Ahmed. Dysregulation of hydrogen sulfide producing enzyme cystathionine γ-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia.
Circulation.
2013 Jun; 127(25):2514-22. doi:
10.1161/circulationaha.113.001631. [PMID: 23704251] - Jingxiang Wu, Jionglin Wei, Xingji You, Xu Chen, Hongwei Zhu, Xiaoyan Zhu, Yujian Liu, Meiying Xu. Inhibition of hydrogen sulfide generation contributes to lung injury after experimental orthotopic lung transplantation.
The Journal of surgical research.
2013 Jun; 182(1):e25-33. doi:
10.1016/j.jss.2012.09.028. [PMID: 23122581] - Barbara Baragatti, Enrica Ciofini, Daria Sodini, Stefano Luin, Francesca Scebba, Flavio Coceani. Hydrogen sulfide in the mouse ductus arteriosus: a naturally occurring relaxant with potential EDHF function.
American journal of physiology. Heart and circulatory physiology.
2013 Apr; 304(7):H927-34. doi:
10.1152/ajpheart.00718.2012. [PMID: 23376828] - Kewen Zhou, Qi Gao, Shuhui Zheng, Sinian Pan, Ping Li, Kun Suo, Tommaso Simoncini, Tinghuai Wang, Xiaodong Fu. 17β-estradiol induces vasorelaxation by stimulating endothelial hydrogen sulfide release.
Molecular human reproduction.
2013 Mar; 19(3):169-76. doi:
10.1093/molehr/gas044. [PMID: 23041593] - Gang Wang, Bing Han, Haoxin Zhou, Linfeng Wu, Yongwei Wang, Guang Jia, Jiachen Lv, Zhuoxin Cheng, Shangha Pan, Ji Liu, Yinan Zhou, Bei Sun. Inhibition of hydrogen sulfide synthesis provides protection for severe acute pancreatitis rats via apoptosis pathway.
Apoptosis : an international journal on programmed cell death.
2013 Jan; 18(1):28-42. doi:
10.1007/s10495-012-0770-x. [PMID: 23054084] - Van P Dam, Jennifer L Scott, Anthony Ross, Robert T Kinobe. Inhibition of cystathionine gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity.
European journal of pharmacology.
2012 Jun; 685(1-3):165-73. doi:
10.1016/j.ejphar.2012.04.030. [PMID: 22546230] - Seyyed Ali Mard, Niloofar Neisi, Ghasem Solgi, Maryam Hassanpour, Marjan Darbor, Maryam Maleki. Gastroprotective effect of NaHS against mucosal lesions induced by ischemia-reperfusion injury in rat.
Digestive diseases and sciences.
2012 Jun; 57(6):1496-503. doi:
10.1007/s10620-012-2051-5. [PMID: 22271414] - H D C Francescato, J R A Chierice, E C S Marin, F Q Cunha, R S Costa, C G A Silva, T M Coimbra. Effect of endogenous hydrogen sulfide inhibition on structural and functional renal disturbances induced by gentamicin.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
2012 Mar; 45(3):244-9. doi:
10.1590/s0100-879x2012007500016. [PMID: 22331137] - Alexander Roy, Abdul H Khan, Mohammed T Islam, Minolfa C Prieto, Dewan S A Majid. Interdependency of cystathione γ-lyase and cystathione β-synthase in hydrogen sulfide-induced blood pressure regulation in rats.
American journal of hypertension.
2012 Jan; 25(1):74-81. doi:
10.1038/ajh.2011.149. [PMID: 21866187] - Heloísa Della Coletta Francescato, Evelyn Cristina Santana Marin, Fernando de Queiroz Cunha, Roberto Silva Costa, Cleonice Giovanini Alves da Silva, Terezila Machado Coimbra. Role of endogenous hydrogen sulfide on renal damage induced by adriamycin injection.
Archives of toxicology.
2011 Dec; 85(12):1597-606. doi:
10.1007/s00204-011-0717-y. [PMID: 21590344] - Yan Gao, Xiaoyi Yao, Yina Zhang, Weimin Li, Kai Kang, Liang Sun, Xueying Sun. The protective role of hydrogen sulfide in myocardial ischemia-reperfusion-induced injury in diabetic rats.
International journal of cardiology.
2011 Oct; 152(2):177-83. doi:
10.1016/j.ijcard.2010.07.012. [PMID: 21316771] - Zhan-Zhi Zhao, Zuo Wang, Guo-Hua Li, Ren Wang, Jian-Miao Tan, Xuan Cao, Rong Suo, Zhi-Sheng Jiang. Hydrogen sulfide inhibits macrophage-derived foam cell formation.
Experimental biology and medicine (Maywood, N.J.).
2011 Feb; 236(2):169-76. doi:
10.1258/ebm.2010.010308. [PMID: 21321313] - Heloísa Della Coletta Francescato, Fernando Queiroz Cunha, Roberto Silva Costa, Fernando Barbosa Júnior, Mirian Aparecida Boim, Carine Prisco Arnoni, Cleonice Giovanini Alves da Silva, Terezila Machado Coimbra. Inhibition of hydrogen sulphide formation reduces cisplatin-induced renal damage.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2011 Feb; 26(2):479-88. doi:
10.1093/ndt/gfq447. [PMID: 20656754] - Jing Zhang, Selena Wei Shan Sio, Shabbir Moochhala, Madhav Bhatia. Role of hydrogen sulfide in severe burn injury-induced inflammation in mice.
Molecular medicine (Cambridge, Mass.).
2010 Sep; 16(9-10):417-24. doi:
10.2119/molmed.2010.00027. [PMID: 20440442] - Jonathan A W Stecyk, Nini Skovgaard, Göran E Nilsson, Tobias Wang. Vasoactivity of hydrogen sulfide in normoxic and anoxic turtles (Trachemys scripta).
American journal of physiology. Regulatory, integrative and comparative physiology.
2010 May; 298(5):R1225-39. doi:
10.1152/ajpregu.00521.2009. [PMID: 20164201] - Seah-Fang Ang, Shabbir M Moochhala, Madhav Bhatia. Hydrogen sulfide promotes transient receptor potential vanilloid 1-mediated neurogenic inflammation in polymicrobial sepsis.
Critical care medicine.
2010 Feb; 38(2):619-28. doi:
10.1097/ccm.0b013e3181c0df00. [PMID: 19851090] - Yang Zhuo, Pei-Fang Chen, Ao-Zhen Zhang, Han Zhong, Chang-Qing Chen, Yi-Zhun Zhu. Cardioprotective effect of hydrogen sulfide in ischemic reperfusion experimental rats and its influence on expression of survivin gene.
Biological & pharmaceutical bulletin.
2009 Aug; 32(8):1406-10. doi:
10.1248/bpb.32.1406. [PMID: 19652381] - Yanfei Wang, Xia Zhao, Hongfang Jin, Hongling Wei, Wei Li, Dingfang Bu, Xiuying Tang, Yali Ren, Chaoshu Tang, Junbao Du. Role of hydrogen sulfide in the development of atherosclerotic lesions in apolipoprotein E knockout mice.
Arteriosclerosis, thrombosis, and vascular biology.
2009 Feb; 29(2):173-9. doi:
10.1161/atvbaha.108.179333. [PMID: 18988885] - Lingyun Wu, Wei Yang, Xuming Jia, Guangdong Yang, Dessislava Duridanova, Kun Cao, Rui Wang. Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats.
Laboratory investigation; a journal of technical methods and pathology.
2009 Jan; 89(1):59-67. doi:
10.1038/labinvest.2008.109. [PMID: 19002107] - Y-Y P Mok, P K Moore. Hydrogen sulphide is pro-inflammatory in haemorrhagic shock.
Inflammation research : official journal of the European Histamine Research Society ... [et al.].
2008 Nov; 57(11):512-8. doi:
10.1007/s00011-008-7231-6. [PMID: 19109743] - Madhav Bhatia, Jenab N Sidhapuriwala, Siaw Wei Ng, Ramasamy Tamizhselvi, Shabbir M Moochhala. Pro-inflammatory effects of hydrogen sulphide on substance P in caerulein-induced acute pancreatitis.
Journal of cellular and molecular medicine.
2008 Apr; 12(2):580-90. doi:
10.1111/j.1582-4934.2007.00131.x. [PMID: 18419599] - Huili Zhang, Liang Zhi, Shabbir Moochhala, Philip K Moore, Madhav Bhatia. Hydrogen sulfide acts as an inflammatory mediator in cecal ligation and puncture-induced sepsis in mice by upregulating the production of cytokines and chemokines via NF-kappaB.
American journal of physiology. Lung cellular and molecular physiology.
2007 Apr; 292(4):L960-71. doi:
10.1152/ajplung.00388.2006. [PMID: 17209138] - Yi Zhun Zhu, Zhong Jing Wang, Peiying Ho, Yoke Yun Loke, Yi Chun Zhu, Shan Hong Huang, Chee Sin Tan, Matt Whiteman, Jia Lu, Philip K Moore. Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats.
Journal of applied physiology (Bethesda, Md. : 1985).
2007 Jan; 102(1):261-8. doi:
10.1152/japplphysiol.00096.2006. [PMID: 17038495] - Huili Zhang, Liang Zhi, Philip K Moore, Madhav Bhatia. Role of hydrogen sulfide in cecal ligation and puncture-induced sepsis in the mouse.
American journal of physiology. Lung cellular and molecular physiology.
2006 Jun; 290(6):L1193-201. doi:
10.1152/ajplung.00489.2005. [PMID: 16428267] - Masao Maekawa, Tadashi Okamura, Noriyuki Kasai, Yuuichi Hori, Karl H Summer, Ryuichi Konno. D-amino-acid oxidase is involved in D-serine-induced nephrotoxicity.
Chemical research in toxicology.
2005 Nov; 18(11):1678-82. doi:
10.1021/tx0500326. [PMID: 16300376] - Marika Collin, Farhana B M Anuar, Oliver Murch, Madhav Bhatia, Philip K Moore, Christoph Thiemermann. Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia.
British journal of pharmacology.
2005 Oct; 146(4):498-505. doi:
10.1038/sj.bjp.0706367. [PMID: 16100527] - Ling Li, Madhav Bhatia, Yi Zhun Zhu, Yi Chun Zhu, Raina Devi Ramnath, Zhong Jing Wang, Farhana Binte Mohammed Anuar, Matthew Whiteman, Manuel Salto-Tellez, Philip K Moore. Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2005 Jul; 19(9):1196-8. doi:
10.1096/fj.04-3583fje. [PMID: 15863703] - Kimihito Fujii, Tadayuki Sakuragawa, Misato Kashiba, Yasoo Sugiura, Mieko Kondo, Kayo Maruyama, Nobuhito Goda, Yuji Nimura, Makoto Suematsu. Hydrogen sulfide as an endogenous modulator of biliary bicarbonate excretion in the rat liver.
Antioxidants & redox signaling.
2005 May; 7(5-6):788-94. doi:
10.1089/ars.2005.7.788. [PMID: 15890026] - Madhav Bhatia, Fei Ling Wong, Di Fu, Hon Yen Lau, Shabbir M Moochhala, Philip K Moore. Role of hydrogen sulfide in acute pancreatitis and associated lung injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
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