Leucodin (BioDeep_00000015388)

natural product PANOMIX_OTCML-2023

代谢物信息卡片

Desacetoxymatricarin

化学式: C15H18O3 (246.1255878)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 1.52%

分子结构信息

SMILES: C12=C(CC[C@@H]3[C@@H]([C@H]1C(=CC2=O)C)OC(=O)[C@H]3C)C
InChI: InChI=1S/C15H18O3/c1-7-4-5-10-9(3)15(17)18-14(10)13-8(2)6-11(16)12(7)13/h6,9-10,13-14H,4-5H2,1-3H3/t9-,10-,13-,14-/m0/s1

描述信息

同义名列表

2 个代谢物同义名

Leucodin; Desacetoxymatricarin

数据库引用编号

17 个数据库交叉引用编号

ChEBI: CHEBI:4441
KEGG: C09394
PubChem: 167683
Metlin: METLIN44414
ChEMBL: CHEMBL517040
KNApSAcK: C00003248
CAS: 17946-87-1
MoNA: Bruker_HCD_library001888
MoNA: VF-NPL-QTOF008320
MoNA: VF-NPL-QTOF008319
MoNA: VF-NPL-QTOF008318
MoNA: VF-NPL-QEHF002730
MoNA: VF-NPL-QEHF002729
MoNA: VF-NPL-QEHF002728
PubChem: 11585
3DMET: B02928
NIKKAJI: J15.382F

分类词条

倍半萜类

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

21 个相关的物种来源信息

282714 - Achillea abrotanoides: 10.1016/S0031-9422(00)97843-9
282720 - Achillea aspleniifolia: 10.1515/ZNC-2002-11-1203
13329 - Achillea millefolium:
1028379 - Achillea santolina:
301866 - Achillea tenuifolia:
301867 - Achillea vermicularis: 10.1016/0305-1978(91)90061-4
282770 - Achillea virescens: 10.1515/ZNC-2002-11-1203
282771 - Achillea wilhelmsii: 10.4268/CJCMM20150722
589716 - Anthemis anthemiformis: 10.1016/S0031-9422(97)00389-0
158231 - Anthemis pseudocotula:
4219 - Artemisia: 10.1055/S-1999-14014
401875 - Artemisia adamsii: 10.1016/S0031-9422(00)83171-4
72338 - Artemisia cana: 10.1021/JO00985A028
72329 - Artemisia herba-alba: 10.1016/S0031-9422(97)00029-0
72345 - Artemisia lucentica: 10.1016/S0031-9422(97)00029-0
223870 - Artemisia princeps: 10.1055/S-2006-957714
72350 - Artemisia reptans: 10.1016/S0031-9422(00)89536-9
75943 - Lactuca serriola: 10.1016/0031-9422(92)83321-O
1885115 - Picris conyzoides: 10.1002/MRC.2801
121888 - Podachaenium eminens: 10.1002/CHIN.199908196
558497 - Stevia pilosa: 10.1021/NP50056A005

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Rosemary Anibogwu, Karl De Jesus, Samjhana Pradhan, Shanae Van Leuven, Kavita Sharma. Sesquiterpene Lactones and Flavonoid from the Leaves of Basin Big Sagebrush (Artemisia tridentata subsp. tridentata): Isolation, Characterization and Biological Activities. Molecules (Basel, Switzerland). 2024 Feb; 29(4):. doi: 10.3390/molecules29040802. [PMID: 38398555]
Luis Arias-Durán, Samuel Estrada-Soto, Monserrat Hernández-Morales, César Millán-Pacheco, Gabriel Navarrete-Vázquez, Rafael Villalobos-Molina, Maximiliano Ibarra-Barajas, Julio C Almanza-Pérez. Antihypertensive and vasorelaxant effect of leucodin and achillin isolated from Achillea millefolium through calcium channel blockade and NO production: In vivo, functional ex vivo and in silico studies. Journal of ethnopharmacology. 2021 Jun; 273(?):113948. doi: 10.1016/j.jep.2021.113948. [PMID: 33610712]
Akram Taleghani, Seyed Ahmad Emami, Zahra Tayarani-Najaran. Artemisia: a promising plant for the treatment of cancer. Bioorganic & medicinal chemistry. 2020 01; 28(1):115180. doi: 10.1016/j.bmc.2019.115180. [PMID: 31784199]
Yue Shang, Xi-Feng Li, Ming-Ji Jin, Ying Li, Yan-Ling Wu, Quan Jin, Yu Zhang, Xia Li, Min Jiang, Ben-Wen Cui, Li-Hua Lian, Ji-Xing Nan. Leucodin attenuates inflammatory response in macrophages and lipid accumulation in steatotic hepatocytes via P2x7 receptor pathway: A potential role in alcoholic liver disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2018 Nov; 107(?):374-381. doi: 10.1016/j.biopha.2018.08.009. [PMID: 30099341]
Elina Karhu, Janne Isojärvi, Pia Vuorela, Leena Hanski, Adyary Fallarero. Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy. Journal of natural products. 2017 10; 80(10):2602-2608. doi: 10.1021/acs.jnatprod.6b01052. [PMID: 29043803]
J Zapata-Martínez, G Sánchez-Toranzo, F Chaín, C A N Catalán, M I Bühler. Effect of guaianolides in the meiosis reinitiation of amphibian oocytes. Zygote (Cambridge, England). 2017 Feb; 25(1):10-16. doi: 10.1017/s0967199416000265. [PMID: 27806737]
Christine Tschiggerl, Franz Bucar. Guaianolides and volatile compounds in chamomile tea. Plant foods for human nutrition (Dordrecht, Netherlands). 2012 Jun; 67(2):129-35. doi: 10.1007/s11130-012-0277-1. [PMID: 22410959]
Özlem Bahadır Acıkara, G Saltan Çitoğlu, S Dall'Acqua, K Smejkal, J Cvačka, M Zemlička. A new triterpene from Scorzonera latifolia (Fisch. and Mey.) DC. Natural product research. 2012; 26(20):1892-7. doi: 10.1080/14786419.2011.625644. [PMID: 21995805]
Klaudia Michalska, Marek Zylewski, Wanda Kisiel. Structure elucidation and complete NMR spectral assignments of two new sesquiterpene lactone xylosides from Lactuca triangulata. Magnetic resonance in chemistry : MRC. 2008 Dec; 46(12):1185-7. doi: 10.1002/mrc.2323. [PMID: 18785195]
R R Bailey. The kidney and antihypertensive therapy. Drugs. 1976; 11 SUPPL 1(?):70-7. doi: 10.2165/00003495-197600111-00019. [PMID: 6253]