Ceruletide (BioDeep_00000015222)

Main id: BioDeep_00000024794

 


代谢物信息卡片


(3S)-3-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-4-carbamoyl-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}butanamido]-3-carboxypropanamido]-3-[4-(sulfooxy)phenyl]propanamido]-3-hydroxybutanamido]acetamido}-3-(1H-indol-3-yl)propanamido]-4-(methylsulfanyl)butanamido]propanoic acid

化学式: C58H73N13O21S2 (1351.4485168)
中文名称: 雨蛙素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C(C(=O)NCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)OS(=O)(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C5CCC(=O)N5)O
InChI: InChI=1S/C58H73N13O21S2/c1-29(72)49(71-57(87)40(23-31-12-14-33(15-13-31)92-94(89,90)91)68-56(86)43(26-48(78)79)69-52(82)37(16-18-44(59)73)65-51(81)36-17-19-45(74)63-36)58(88)62-28-46(75)64-41(24-32-27-61-35-11-7-6-10-34(32)35)54(84)66-38(20-21-93-2)53(83)70-42(25-47(76)77)55(85)67-39(50(60)80)22-30-8-4-3-5-9-30/h3-15,27,29,36-43,49,61,72H,16-26,28H2,1-2H3,(H2,59,73)(H2,60,80)(H,62,88)(H,63,74)(H,64,75)(H,65,81)(H,66,84)(H,67,85)(H,68,86)(H,69,82)(H,70,83)(H,71,87)(H,76,77)(H,78,79)(H,89,90,91)/t29-,36+,37+,38+,39+,40+,41+,42+,43+,49+/m1/s1

描述信息

V - Various > V04 - Diagnostic agents > V04C - Other diagnostic agents > V04CC - Tests for bile duct patency
Ceruletide is a decapeptide and a potent cholecystokinin receptor agonist. Ceruletide is a safe and effective cholecystokinetic agent with a direct spasmogenic effect on the gallbladder muscle and bile ducts[1].

同义名列表

6 个代谢物同义名

Caerulein ammonium salt; Ceruletide; (3S)-3-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-3-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-4-carbamoyl-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}butanamido]-3-carboxypropanamido]-3-[4-(sulfooxy)phenyl]propanamido]-3-hydroxybutanamido]acetamido}-3-(1H-indol-3-yl)propanamido]-4-(methylsulfanyl)butanamido]propanoic acid; Caerulein; Cerulein; FI-6934



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Xiao Han, Jingpiao Bao, Jianbo Ni, Bin Li, Pengli Song, Rong Wan, Xingpeng Wang, Guoyong Hu, Congying Chen. Qing Xia Jie Yi Formula granules alleviated acute pancreatitis through inhibition of M1 macrophage polarization by suppressing glycolysis. Journal of ethnopharmacology. 2024 May; 325(?):117750. doi: 10.1016/j.jep.2024.117750. [PMID: 38216100]
  • Xinjuan Fu, Zhigang Xiu, Qianqian Xu, Rui Yue, Hongwei Xu. Interleukin-22 Alleviates Caerulein-Induced Acute Pancreatitis by Activating AKT/mTOR Pathway. Digestive diseases and sciences. 2024 May; 69(5):1691-1700. doi: 10.1007/s10620-024-08360-6. [PMID: 38466463]
  • Jin Tao, Yiyi Zhang, Yinshi Huang, Min Xu. The role of iron and ferroptosis in the pathogenesis of acute pancreatitis. Journal of histotechnology. 2023 Dec; 46(4):184-193. doi: 10.1080/01478885.2023.2261093. [PMID: 37823564]
  • Fei Cao, Jie Xiang, Yaodong Wang, Xijie Chen, Xirong Lu, Xingmeng Xu, Lin Chen, Yinghong Fan, Chenchen Yuan, Xiaowu Dong, Qingtian Zhu, Chenxia Han, Guotao Lu, Qing Xia, Weiwei Chen. Chaiqin chengqi decoction alleviates acute pancreatitis by targeting gasdermin D-mediated pyroptosis. Journal of ethnopharmacology. 2023 Jul; 318(Pt A):116920. doi: 10.1016/j.jep.2023.116920. [PMID: 37480969]
  • Ewa Tomaszewska, Małgorzata Świątkiewicz, Siemowit Muszyński, Janine Donaldson, Katarzyna Ropka-Molik, Marcin B Arciszewski, Maciej Murawski, Tomasz Schwarz, Piotr Dobrowolski, Sylwia Szymańczyk, Sławomir Dresler, Joanna Bonior. Repetitive Cerulein-Induced Chronic Pancreatitis in Growing Pigs-A Pilot Study. International journal of molecular sciences. 2023 Apr; 24(9):. doi: 10.3390/ijms24097715. [PMID: 37175426]
  • Wan-Jun Yang, Rong-Chang Cao, Wang Xiao, Xiao-Lou Zhang, Hao Xu, Meng Wang, Zhi-Tao Zhou, Huo-Ji Chen, Jia Xu, Xue-Mei Chen, Jun-Ling Zeng, Shu-Ji Li, Min Luo, Yan-Jiang Han, Xiao-Bing Yang, Guo-Dong Feng, Yu-Heng Lu, Yuan-Yuan Ni, Chan-Gui Wu, Jun-Jie Bai, Zi-Qi Yuan, Jin Jin, Guo-Wei Zhang. Acinar ATP8b1/LPC pathway promotes macrophage efferocytosis and clearance of inflammation during chronic pancreatitis development. Cell death & disease. 2022 10; 13(10):893. doi: 10.1038/s41419-022-05322-6. [PMID: 36273194]
  • Fu Li, Meng Chen, Jianmei Ji, Rui Tang, Jinxin Huang, Xiwen Zhang, Jinzhong Yu. Pachymic acid alleviates experimental pancreatic fibrosis through repressing NLRP3 inflammasome activation. Bioscience, biotechnology, and biochemistry. 2022 Oct; 86(11):1497-1505. doi: 10.1093/bbb/zbac114. [PMID: 36095138]
  • Yujin Lee, Joo Weon Lim, Hyeyoung Kim. α‑lipoic acid inhibits cerulein/resistin‑induced expression of interleukin‑6 by activating peroxisome proliferator‑activated receptor‑γ in pancreatic acinar cells. Molecular medicine reports. 2022 Aug; 26(2):. doi: 10.3892/mmr.2022.12780. [PMID: 35730599]
  • Yamini Chelpuri, Shivakumar Pabbathi, Gopala Reddy Alla, Ravi Kumar Yadala, Mounika Kamishetti, Anil Kumar Banothu, Ramya Boinepally, Kala Kumar Bharani, Amit Khurana. Tropolone derivative hinokitiol ameliorates cerulein-induced acute pancreatitis in mice. International immunopharmacology. 2022 Aug; 109(?):108915. doi: 10.1016/j.intimp.2022.108915. [PMID: 35679663]
  • Ji-Won Choi, Joon Yeon Shin, Ziqi Zhou, Dong-Uk Kim, Bitna Kweon, Hyuncheol Oh, Youn-Chul Kim, Ho-Joon Song, Gi-Sang Bae, Sung-Joo Park. Stem bark of Fraxinus rhynchophylla ameliorates the severity of pancreatic fibrosis by regulating the TGF-β/Smad signaling pathway. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 2022 06; 70(5):1285-1292. doi: 10.1136/jim-2021-002169. [PMID: 35078865]
  • Tao Xu, Liping Sheng, Xianwen Guo, Zhen Ding. Free Fatty Acid Increases the Expression of NLRP3-Caspase1 in Adipose Tissue Macrophages in Obese Severe Acute Pancreatitis. Digestive diseases and sciences. 2022 Jun; 67(6):2220-2231. doi: 10.1007/s10620-021-07027-w. [PMID: 34114155]
  • Zheng-Nan Ren, Jun Yang, Meng-Ya Zhang, Yi-Wen Huang, Dong-Xiao Song, Xun Sun, Li-Long Pan, Jia Sun. A novel resveratrol analog upregulates sirtuin 1 and inhibits inflammatory cell infiltration in acute pancreatitis. Acta pharmacologica Sinica. 2022 May; 43(5):1264-1273. doi: 10.1038/s41401-021-00744-y. [PMID: 34363008]
  • Li Zhang, Juanjuan Shi, Dan Du, Ningning Niu, Shiyu Liu, Xiaotong Yang, Ping Lu, Xuqing Shen, Na Shi, Linbo Yao, Ruling Zhang, Guoyong Hu, Guotao Lu, Qingtian Zhu, Tao Zeng, Tingting Liu, Qing Xia, Wei Huang, Jing Xue. Ketogenesis acts as an endogenous protective programme to restrain inflammatory macrophage activation during acute pancreatitis. EBioMedicine. 2022 Apr; 78(?):103959. doi: 10.1016/j.ebiom.2022.103959. [PMID: 35339899]
  • Cristina M Hagen, Eva Roth, Theresia Reding Graf, François Verrey, Rolf Graf, Anurag Gupta, Giovanni Pellegrini, Nadège Poncet, Simone Mafalda Rodrigues Camargo. Loss of LAT1 sex-dependently delays recovery after caerulein-induced acute pancreatitis. World journal of gastroenterology. 2022 Mar; 28(10):1024-1054. doi: 10.3748/wjg.v28.i10.1024. [PMID: 35431492]
  • Jing Wang, Jing Huang, Lili Huang. TSPAN1 silencing protects against cerulein-induced pancreatic acinar cell injury via targeting AGR2. Drug development research. 2022 02; 83(1):158-166. doi: 10.1002/ddr.21855. [PMID: 34212407]
  • Jiachen Lv, Liang Ji, Gang Wang, Bei Sun, Jinxue Tong. Alcohol Aggravates Acute Pancreatitis by Impairing Autophagic Flux Through Activation of AMPK Signaling Pathway. Digestive diseases and sciences. 2022 02; 67(2):524-535. doi: 10.1007/s10620-021-06870-1. [PMID: 33555515]
  • Song Ren, Longfei Pan, Linqing Yang, Zequn Niu, Liming Wang, Yanxia Gao, Jie Liu, Zhong Liu, Honghong Pei. Interfering hsa_circ_0073748 alleviates caerulein-induced ductal cell injury in acute pancreatitis by inhibiting miR-132-3p/TRAF3/NF-κB pathway. Cell cycle (Georgetown, Tex.). 2022 01; 21(2):172-186. doi: 10.1080/15384101.2021.2014653. [PMID: 34882521]
  • Ke Liu, Jiao Liu, Borong Zou, Changfeng Li, Herbert J Zeh, Rui Kang, Guido Kroemer, Jun Huang, Daolin Tang. Trypsin-Mediated Sensitization to Ferroptosis Increases the Severity of Pancreatitis in Mice. Cellular and molecular gastroenterology and hepatology. 2022; 13(2):483-500. doi: 10.1016/j.jcmgh.2021.09.008. [PMID: 34562639]
  • J Tao, H Cheema, K Kesh, V Dudeja, R Dawra, S Roy. Chronic pancreatitis in a caerulein-induced mouse model is associated with an altered gut microbiome. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2022 Jan; 22(1):30-42. doi: 10.1016/j.pan.2021.12.003. [PMID: 34949545]
  • Qiang Liu, Lingyun Li, Dongchao Xu, Jianpeng Zhu, Zhicheng Huang, Jianfeng Yang, Sile Cheng, Ye Gu, Liyun Zheng, Xiaofeng Zhang, Hongzhang Shen. Identification of novel immune-related targets mediating disease progression in acute pancreatitis. Frontiers in cellular and infection microbiology. 2022; 12(?):1052466. doi: 10.3389/fcimb.2022.1052466. [PMID: 36590588]
  • Biwei Wei, Yahui Gong, Huiying Yang, Jie Zhou, Zhou Su, Zhihai Liang. Role of tumor necrosis factor receptor‑associated factor 6 in pyroptosis during acute pancreatitis. Molecular medicine reports. 2021 12; 24(6):. doi: 10.3892/mmr.2021.12488. [PMID: 34643253]
  • Wenchao Yu, Min Zhang, Xin Li, Ning Pan, Xia Bian, Wei Wu. Protective Effect of miR-193a-5p and miR-320-5p on Caerulein-Induced Injury in AR42J Cells. Digestive diseases and sciences. 2021 12; 66(12):4333-4343. doi: 10.1007/s10620-020-06800-7. [PMID: 33405047]
  • Shuhei Takauji, Hiroaki Konishi, Mikihiro Fujiya, Nobuhiro Ueno, Hiroki Tanaka, Hiroki Sato, Shotaro Isozaki, Shin Kashima, Kentaro Moriichi, Yusuke Mizukami, Toshikatsu Okumura. Polyphosphate, Derived from Lactobacillus brevis, Modulates the Intestinal Microbiome and Attenuates Acute Pancreatitis. Digestive diseases and sciences. 2021 11; 66(11):3872-3884. doi: 10.1007/s10620-020-06747-9. [PMID: 33492535]
  • Yin Xian, Yi Wu, Ming He, Junming Cheng, Xiaodong Lv, Yixing Ren. Sleeve Gastrectomy Attenuates the Severity of Cerulein-Induced Acute Pancreatitis in Obese Rats. Obesity surgery. 2021 09; 31(9):4107-4117. doi: 10.1007/s11695-021-05521-8. [PMID: 34152559]
  • Ren-Jie Chang, Hui-Lin Wang, Meng-Bin Qin, Zhi-Hai Liang, Jia-Ping He, Yu-Le Wei, Hong-Zong Fu, Guo-Du Tang. Ghrelin inhibits IKKβ/NF-κB activation and reduces pro-inflammatory cytokine production in pancreatic acinar AR42J cells treated with cerulein. Hepatobiliary & pancreatic diseases international : HBPD INT. 2021 Aug; 20(4):366-375. doi: 10.1016/j.hbpd.2020.05.004. [PMID: 32553660]
  • Yaling Yi, Xingshen Sun, Bo Liang, Nan He, Katherine N Gibson-Corley, Andrew W Norris, John F Engelhardt, Aliye Uc. Acute pancreatitis-induced islet dysfunction in ferrets. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2021 Aug; 21(5):839-847. doi: 10.1016/j.pan.2021.04.008. [PMID: 33994067]
  • Jason I E Bruce, Rosa Sánchez-Alvarez, Maria Dolors Sans, Sarah A Sugden, Nathan Qi, Andrew D James, John A Williams. Insulin protects acinar cells during pancreatitis by preserving glycolytic ATP supply to calcium pumps. Nature communications. 2021 07; 12(1):4386. doi: 10.1038/s41467-021-24506-w. [PMID: 34282152]
  • Xiao-Die Wang, Wei-Li Yu, Yun Sun. Activation of AMPK restored impaired autophagy and inhibited inflammation reaction by up-regulating SIRT1 in acute pancreatitis. Life sciences. 2021 Jul; 277(?):119435. doi: 10.1016/j.lfs.2021.119435. [PMID: 33781829]
  • Chenxia Han, Dan Du, Yongjian Wen, Jiawang Li, Rui Wang, Tao Jin, Jingyu Yang, Na Shi, Kun Jiang, Lihui Deng, Xianghui Fu, Rajarshi Mukherjee, John A Windsor, Jiwon Hong, Anthony R Phillips, Robert Sutton, Wei Huang, Tingting Liu, Qing Xia. Chaiqin chengqi decoction ameliorates acute pancreatitis in mice via inhibition of neuron activation-mediated acinar cell SP/NK1R signaling pathways. Journal of ethnopharmacology. 2021 Jun; 274(?):114029. doi: 10.1016/j.jep.2021.114029. [PMID: 33731310]
  • Shengchuan Chen, Jingfei Zhu, Li-Qiong Sun, Siying Liu, Tan Zhang, Yuepeng Jin, Chaohao Huang, Dapei Li, Haiping Yao, Jian Huang, Yanghua Qin, Mengtao Zhou, Gang Chen, Qiyu Zhang, Feng Ma. LincRNA-EPS alleviates severe acute pancreatitis by suppressing HMGB1-triggered inflammation in pancreatic macrophages. Immunology. 2021 06; 163(2):201-219. doi: 10.1111/imm.13313. [PMID: 33512718]
  • Rajasa Randhi, Melissa Damon, Kirsty J Dixon. Selective inhibition of soluble TNF using XPro1595 relieves pain and attenuates cerulein-induced pathology in mice. BMC gastroenterology. 2021 May; 21(1):243. doi: 10.1186/s12876-021-01827-0. [PMID: 34049483]
  • Ge Liang, Jingyu Yang, Tingting Liu, Shisheng Wang, Yongjian Wen, Chenxia Han, Yan Huang, Rui Wang, Yiqin Wang, Liqiang Hu, Guangzhi Wang, Fei Li, Joel D A Tyndall, Lihui Deng, Dan Du, Qing Xia. A multi-strategy platform for quality control and Q-markers screen of Chaiqin chengqi decoction. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2021 May; 85(?):153525. doi: 10.1016/j.phymed.2021.153525. [PMID: 33740732]
  • Kun Li, Hongling Yin, Yi Duan, Peizhen Lai, Yancheng Cai, Youzhen Wei. Pre-inhalation of hydrogen-rich gases protect against caerulein-induced mouse acute pancreatitis while enhance the pancreatic Hsp60 protein expression. BMC gastroenterology. 2021 Apr; 21(1):178. doi: 10.1186/s12876-021-01640-9. [PMID: 33874887]
  • Sapana Bansod, Shrilekha Chilvery, Mohd Aslam Saifi, Tridip Jyoti Das, Hui Tag, Chandraiah Godugu. Borneol protects against cerulein-induced oxidative stress and inflammation in acute pancreatitis mice model. Environmental toxicology. 2021 Apr; 36(4):530-539. doi: 10.1002/tox.23058. [PMID: 33166053]
  • Bo Sheng, Lei Zhao, Xuefeng Zang, Jie Zhen, Yang Liu, Weishuai Bian, Wei Chen. Quercetin inhibits caerulein-induced acute pancreatitis through regulating miR-216b by targeting MAP2K6 and NEAT1. Inflammopharmacology. 2021 Apr; 29(2):549-559. doi: 10.1007/s10787-020-00767-7. [PMID: 33051781]
  • Zhu-Fen Zhao, Ye Zhang, Yang Sun, Chun-Hai Zhang, Ming-Wei Liu. Protective effects of baicalin on caerulein-induced AR42J pancreatic acinar cells by attenuating oxidative stress through miR-136-5p downregulation. Science progress. 2021 Apr; 104(2):368504211026118. doi: 10.1177/00368504211026118. [PMID: 34176350]
  • Tarek El-Hamoly, Zoltán Hajnády, Máté Nagy-Pénzes, Edina Bakondi, Zsolt Regdon, Máté A Demény, Katalin Kovács, Csaba Hegedűs, Sahar S Abd El-Rahman, Éva Szabó, József Maléth, Péter Hegyi, László Virág. Poly(ADP-Ribose) Polymerase 1 Promotes Inflammation and Fibrosis in a Mouse Model of Chronic Pancreatitis. International journal of molecular sciences. 2021 Mar; 22(7):. doi: 10.3390/ijms22073593. [PMID: 33808340]
  • Dóra Mosztbacher, Miklós Sahin-Tóth. Mouse model suggests limited role for human mesotrypsin in pancreatitis. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2021 Mar; 21(2):342-352. doi: 10.1016/j.pan.2021.01.007. [PMID: 33526384]
  • Baoyi Xiong, Wencheng Zhang, Zeyu Wu, Rui Liu, Chengying Yang, Ailing Hui, Xusheng Huang, Zhaojun Xian. Okra pectin relieves inflammatory response and protects damaged intestinal barrier in caerulein-induced acute pancreatic model. Journal of the science of food and agriculture. 2021 Feb; 101(3):863-870. doi: 10.1002/jsfa.10693. [PMID: 33433910]
  • Sapana Bansod, Chandraiah Godugu. Nimbolide ameliorates pancreatic inflammation and apoptosis by modulating NF-κB/SIRT1 and apoptosis signaling in acute pancreatitis model. International immunopharmacology. 2021 Jan; 90(?):107246. doi: 10.1016/j.intimp.2020.107246. [PMID: 33310297]
  • Xiao-Min Luo, Cen Yan, Yue-Jie Zhang, Ling-Jia Meng, Guo-Tao Lu, Ji-Ming Yin, Ying-Mei Feng. Diabetic Bone Marrow Cell Injection Accelerated Acute Pancreatitis Progression. Journal of immunology research. 2021; 2021(?):5123823. doi: 10.1155/2021/5123823. [PMID: 34485535]
  • Jessica Hung, Rohni Awasthi, Alexander L Klibanov, Kimberly A Kelly. Identification of Novel Ligands for Targeted Antifibrotic Therapy of Chronic Pancreatitis. International journal of nanomedicine. 2021; 16(?):5495-5512. doi: 10.2147/ijn.s318331. [PMID: 34429596]
  • Xinyi Yang, Runsheng Li, Lu Xu, Feng Qian, Lei Sun. Serum amyloid A3 is required for caerulein-induced acute pancreatitis through induction of RIP3-dependent necroptosis. Immunology and cell biology. 2021 01; 99(1):34-48. doi: 10.1111/imcb.12382. [PMID: 32725692]
  • Qingtian Zhu, Lu Hao, Qinhao Shen, Jiajia Pan, Weili Liu, Weijuan Gong, Lianghao Hu, Weiming Xiao, Mei Wang, Xinnong Liu, Yanbing Ding, Guotao Lu. CaMK II Inhibition Attenuates ROS Dependent Necroptosis in Acinar Cells and Protects against Acute Pancreatitis in Mice. Oxidative medicine and cellular longevity. 2021; 2021(?):4187398. doi: 10.1155/2021/4187398. [PMID: 34840668]
  • Hanan H Hagar, Sarah A Almubrik, Nada M Attia, Sarah N Aljasser. Mesna Alleviates Cerulein-Induced Acute Pancreatitis by Inhibiting the Inflammatory Response and Oxidative Stress in Experimental Rats. Digestive diseases and sciences. 2020 12; 65(12):3583-3591. doi: 10.1007/s10620-020-06072-1. [PMID: 32088797]
  • Yongjian Wen, Chenxia Han, Tingting Liu, Rui Wang, Wenhao Cai, Jingyu Yang, Ge Liang, Linbo Yao, Na Shi, Xianghui Fu, Lihui Deng, Robert Sutton, John A Windsor, Jiwon Hong, Anthony R Phillips, Dan Du, Wei Huang, Qing Xia. Chaiqin chengqi decoction alleviates severity of acute pancreatitis via inhibition of TLR4 and NLRP3 inflammasome: Identification of bioactive ingredients via pharmacological sub-network analysis and experimental validation. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2020 Dec; 79(?):153328. doi: 10.1016/j.phymed.2020.153328. [PMID: 33007730]
  • Xiaoqiang Liang, Cheng Hu, Congying Liu, Kui Yu, Jingzhe Zhang, Yiqun Jia. Dihydrokaempferol (DHK) ameliorates severe acute pancreatitis (SAP) via Keap1/Nrf2 pathway. Life sciences. 2020 Nov; 261(?):118340. doi: 10.1016/j.lfs.2020.118340. [PMID: 32860805]
  • Lei Zhou, Jie-Hui Tan, Wan-Yan Zhou, Jia Xu, Shi-Jing Ren, Zhen-Yu Lin, Xue-Mei Chen, Guo-Wei Zhang. P53 Activated by ER Stress Aggravates Caerulein-Induced Acute Pancreatitis Progression by Inducing Acinar Cell Apoptosis. Digestive diseases and sciences. 2020 11; 65(11):3211-3222. doi: 10.1007/s10620-020-06052-5. [PMID: 31974911]
  • L Xia, Z Xu, X Zhou, F Bergmann, N Grabe, M W Büchler, J P Neoptolemos, T Hackert, G Kroemer, F Fortunato. Impaired autophagy increases susceptibility to endotoxin-induced chronic pancreatitis. Cell death & disease. 2020 10; 11(10):889. doi: 10.1038/s41419-020-03050-3. [PMID: 33087696]
  • Ana Ferrero-Andrés, Arnau Panisello-Roselló, Joan Roselló-Catafau, Emma Folch-Puy. Polyethylene glycol 35 ameliorates pancreatic inflammatory response in cerulein-induced acute pancreatitis in rats. World journal of gastroenterology. 2020 Oct; 26(39):5970-5982. doi: 10.3748/wjg.v26.i39.5970. [PMID: 33132648]
  • Dilek Özbeyli, Esra Bihter Gürler, Hülya Buzcu, Özlem Tuğçe Çilingir-Kaya, Muhammet Emin Çam, Meral Yüksel. Astaxanthin alleviates oxidative damage in acute pancreatitis via direct antioxidant mechanisms. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology. 2020 10; 31(10):706-712. doi: 10.5152/tjg.2020.19520. [PMID: 33169708]
  • Yi Zhu, Shuguang Liu, Feng Wang. MicroRNA MiR-27a-5p Alleviates the Cerulein-Induced Cell Apoptosis and Inflammatory Injury of AR42J Cells by Targeting Traf3 in Acute Pancreatitis. Inflammation. 2020 Oct; 43(5):1988-1998. doi: 10.1007/s10753-020-01272-3. [PMID: 32647955]
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