nafcillin sodium (BioDeep_00000015187)

   


代谢物信息卡片


nafcillin sodium

化学式: C21H21N2NaO5S (436.10688160000007)
中文名称: 纳夫西林钠盐
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCOC1=C(C2=CC=CC=C2C=C1)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na+]
InChI: /q

描述信息

D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

同义名列表

1 个代谢物同义名

nafcillin sodium



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Lynn Chan, Noreen H Chan-Tompkins, James Como, Anthony J Guarascio. Retrospective Analysis of Adverse Drug Events Between Nafcillin Versus Cefazolin for Treatment of Methicillin-Susceptible Staphylococcus aureus Infections. The Annals of pharmacotherapy. 2020 07; 54(7):662-668. doi: 10.1177/1060028019897267. [PMID: 31888347]
  • Tristan T Timbrook, Lydia McKay, Jesse D Sutton, Emily S Spivak. Disproportionality Analysis of Safety with Nafcillin and Oxacillin with the FDA Adverse Event Reporting System (FAERS). Antimicrobial agents and chemotherapy. 2020 02; 64(3):. doi: 10.1128/aac.01818-19. [PMID: 31844017]
  • Marguerite L Monogue, Jessica K Ortwine, Wenjing Wei, Khalid Eljaaly, Kavita P Bhavan. Nafcillin versus cefazolin for the treatment of methicillin-susceptible Staphylococcus aureus bacteremia. Journal of infection and public health. 2018 Sep; 11(5):727-731. doi: 10.1016/j.jiph.2018.02.004. [PMID: 29526442]
  • Corey C Burrelli, Eleanor K Broadbent, Alice Margulis, Graham M Snyder, Howard S Gold, Christopher McCoy, Monica V Mahoney, Elizabeth B Hirsch. Does the Beta-Lactam Matter? Nafcillin versus Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bloodstream Infections. Chemotherapy. 2018; 63(6):345-351. doi: 10.1159/000499033. [PMID: 30965335]
  • Brady S Moffett, Jennifer Morris, Charissa Kam, Marianne Galati, Ankhi Dutta, Ayse Akcan-Arikan. Vancomycin associated acute kidney injury in pediatric patients. PloS one. 2018; 13(10):e0202439. doi: 10.1371/journal.pone.0202439. [PMID: 30281600]
  • Russell J Benefield, Brian C Barker, Christopher M Gast, Donald P Alexander. Patient Variables Associated with Nafcillin Plasma Concentrations and Toxicity. Pharmacotherapy. 2016 09; 36(9):994-1002. doi: 10.1002/phar.1805. [PMID: 27485941]
  • J Alexander Viehman, Louise-Marie Oleksiuk, Kathleen R Sheridan, Karin E Byers, Peimei He, Bonnie A Falcione, Ryan K Shields. Adverse Events Lead to Drug Discontinuation More Commonly among Patients Who Receive Nafcillin than among Those Who Receive Oxacillin. Antimicrobial agents and chemotherapy. 2016 05; 60(5):3090-5. doi: 10.1128/aac.03122-15. [PMID: 26976858]
  • Timothy John Barreiro, Denis D Asiimwe, David Gemmel, Patrick Brine. Catastrophic chest pain: blinded by cardiopulmonary disease. BMJ case reports. 2015 Jul; 2015(?):. doi: 10.1136/bcr-2015-209928. [PMID: 26135489]
  • Craig B Whitman, Melissa J Wike. Possible case of nafcillin-induced acute interstitial nephritis. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 2012 Jun; 69(12):1049-53. doi: 10.2146/ajhp110357. [PMID: 22644982]
  • Mine-Ok Chang, Eun Sil Koh, Min Ju Kim, Seok Joon Shin, Cheol Whee Park, Yoon Sik Chang, Sungjin Chung. Nafcillin-induced bullous skin eruption with granulocytopenia in a patient with end-stage renal disease. Internal medicine (Tokyo, Japan). 2012; 51(3):287-9. doi: 10.2169/internalmedicine.51.6091. [PMID: 22293804]
  • Mohan Pammi, Rong Liang, John M Hicks, Jim Barrish, James Versalovic. Farnesol decreases biofilms of Staphylococcus epidermidis and exhibits synergy with nafcillin and vancomycin. Pediatric research. 2011 Dec; 70(6):578-83. doi: 10.1203/pdr.0b013e318232a984. [PMID: 21857375]
  • M Shawn Riser, Christopher M Bland, Celeste N Rudisill, P Brandon Bookstaver. Cerebrospinal fluid penetration of high-dose daptomycin in suspected Staphylococcus aureus meningitis. The Annals of pharmacotherapy. 2010 Nov; 44(11):1832-5. doi: 10.1345/aph.1p307. [PMID: 20959502]
  • Tobin Hoppes, Marios Prikis, Alan Segal. Four cases of nafcillin-associated acute interstitial nephritis in one institution. Nature clinical practice. Nephrology. 2007 Aug; 3(8):456-61. doi: 10.1038/ncpneph0561. [PMID: 17653125]
  • Javier L Urraca, María C Moreno-Bondi, Guillermo Orellana, Börje Sellergren, Andrew J Hall. Molecularly imprinted polymers as antibody mimics in automated on-line fluorescent competitive assays. Analytical chemistry. 2007 Jul; 79(13):4915-23. doi: 10.1021/ac070277i. [PMID: 17550229]
  • A Fernández-González, R Badía Laíño, M E Diaz-García, L Guardia, A Viale. Assessment of molecularly imprinted sol-gel materials for selective room temperature phosphorescence recognition of nafcillin. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2004 May; 804(1):247-54. doi: 10.1016/j.jchromb.2003.12.030. [PMID: 15093178]
  • C C Lang, S K Jamal, Z Mohamed, M R Mustafa, A M Mustafa, T C Lee. Evidence of an interaction between nifedipine and nafcillin in humans. British journal of clinical pharmacology. 2003 Jun; 55(6):588-90. doi: 10.1046/j.1365-2125.2003.01789.x. [PMID: 12814453]
  • J M Ruso, P Taboada, L M Varela, D Attwood, V Mosquera. Adsorption of an amphiphilic penicillin onto human serum albumin: characterisation of the complex. Biophysical chemistry. 2001 Aug; 92(1-2):141-53. doi: 10.1016/s0301-4622(01)00196-x. [PMID: 11527586]
  • M E Shirtliff, J H Calhoun, J T Mader. Comparative evaluation of oral levofloxacin and parenteral nafcillin in the treatment of experimental methicillin-susceptible Staphylococcus aureus osteomyelitis in rabbits. The Journal of antimicrobial chemotherapy. 2001 Aug; 48(2):253-8. doi: 10.1093/jac/48.2.253. [PMID: 11481297]
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  • L K Sørensen, L K Snor, T Elkaer, H Hansen. Simultaneous determination of seven penicillins in muscle, liver and kidney tissues from cattle and pigs by a multiresidue high-performance liquid chromatographic method. Journal of chromatography. B, Biomedical sciences and applications. 1999 Nov; 734(2):307-18. doi: 10.1016/s0378-4347(99)00389-8. [PMID: 10595728]
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  • P J Pascoe, J E Ilkiw, P H Kass, L D Cowgill. Case-control study of the association between intraoperative administration of nafcillin and acute postoperative development of azotemia. Journal of the American Veterinary Medical Association. 1996 Apr; 208(7):1043-7. doi: NULL. [PMID: 8621315]
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  • F Jahansouz, J M Kriett, C M Smith, S W Jamieson. Potentiation of cyclosporine nephrotoxicity by nafcillin in lung transplant recipients. Transplantation. 1993 May; 55(5):1045-8. doi: 10.1097/00007890-199305000-00018. [PMID: 8497878]
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  • A Dasgupta, D A Dennen, R Dean. Effect of serum albumin on in vitro displacement of valproic acid by ceftriaxone and nafcillin. Clinical chemistry. 1990 May; 36(5):825-6. doi: 10.1093/clinchem/36.5.825. [PMID: 2110875]
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  • J D Ogle, J G Noel, R M Sramkoski, C K Ogle, J W Alexander. Effect of antibiotics on CR1 receptor levels of human neutrophils and on the binding and phagocytosis of opsonized polystyrene microspheres by these leucocytes. Burns : journal of the International Society for Burn Injuries. 1989 Jun; 15(3):141-4. doi: 10.1016/0305-4179(89)90167-8. [PMID: 2527039]
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  • P A Casthely, M A Ergin, T Yoganathan, L Rabinowitz, K Goodman, P N Fyman, L Abrams. Hemodynamic changes after nafcillin administration during coronary artery bypass surgery. Journal of cardiothoracic anesthesia. 1989 Apr; 3(2):168-71. doi: 10.1016/s0888-6296(89)92498-8. [PMID: 2519941]
  • P Fan-Havard, M C Nahata. A rapid analysis of nafcillin using high-performance liquid chromatography. Therapeutic drug monitoring. 1989; 11(1):105-8. doi: 10.1097/00007691-198901000-00021. [PMID: 2911843]
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  • J T Mader, L T Morrison, K R Adams. Comparative evaluation of A-56619, A-56620, and nafcillin in the treatment of experimental Staphylococcus aureus osteomyelitis. Antimicrobial agents and chemotherapy. 1987 Feb; 31(2):259-63. doi: 10.1128/aac.31.2.259. [PMID: 3566251]
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