Cefuroxime sodium (BioDeep_00000015186)
代谢物信息卡片
Cefuroxime sodium
化学式: C16H15N4NaO8S (446.050827)
中文名称: 头孢呋辛钠
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CO/N=C(/c1ccco1)\C(=O)N[C@@H]1C(=O)N2C(=C(COC(=O)N)CS[C@H]12)C(=O)[O-].[Na+]
InChI: /q
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
同义名列表
1 个代谢物同义名
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:3517
- KEGG: C08108
- KEGGdrug: D00915
- PubChem: 23670318
- Metlin: METLIN66823
- ChEMBL: CHEMBL2146124
- MeSH: Cefuroxime
- CAS: 56238-63-2
- PubChem: 10308
- NIKKAJI: J296.618B
- RefMet: Cefuroxime sodium
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ding Huang, Sha Chen, Yanqing Cai, Liye Shi, Yiru Shi, Min Zeng, Weiwei Cheng, Jian Zhang, Hongjie Pan. Adjunctive azithromycin prophylaxis protects women from uterine cesarean scar defect: A randomized controlled trial.
Acta obstetricia et gynecologica Scandinavica.
2022 08; 101(8):889-900. doi:
10.1111/aogs.14387. [PMID: 35645037] - Nishat Bhatia, Asha Kumari, Nitika Thakur, Gaurav Sharma, Ragini Raj Singh, Rahul Sharma. Phytochemically stabilized chitosan encapsulated Cu and Ag nanocomposites to remove cefuroxime axetil and pathogens from the environment.
International journal of biological macromolecules.
2022 Jul; 212(?):451-464. doi:
10.1016/j.ijbiomac.2022.05.143. [PMID: 35618089] - Robert Strengen Bigseth, Håkon Sandholdt, Andreas Petersen, Christian Østergaard, Thomas Benfield, Louise Thorlacius-Ussing. Comparable Effectiveness of Cefuroxime and Piperacillin-Tazobactam as Empirical Therapy for Methicillin-Susceptible Staphylococcus aureus Bacteremia.
Microbiology spectrum.
2022 06; 10(3):e0153021. doi:
10.1128/spectrum.01530-21. [PMID: 35438533] - Sara Kousgaard Tøstesen, Pelle Hanberg, Mats Bue, Theis Muncholm Thillemann, Thomas Falstie-Jensen, Mikkel Tøttrup, Martin Bruun Knudsen, Anne Vibeke Schmedes, Maiken Stilling. Weight-based cefuroxime dosing provides comparable orthopedic target tissue concentrations between weight groups - a microdialysis porcine study.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
2022 Feb; 130(2):111-118. doi:
10.1111/apm.13198. [PMID: 34862642] - Desie Kasew, Blen Desalegn, Mihret Aynalem, Sosina Tila, Dureti Diriba, Beimnet Afework, Michael Getie, Sirak Biset, Habtamu Wondifraw Baynes. Antimicrobial resistance trend of bacterial uropathogens at the university of Gondar comprehensive specialized hospital, northwest Ethiopia: A 10 years retrospective study.
PloS one.
2022; 17(4):e0266878. doi:
10.1371/journal.pone.0266878. [PMID: 35404978] - Verena Bossung, Mariia Lupatsii, Lkhagvademberel Dashdorj, Oronzo Tassiello, Sinje Jonassen, Julia Pagel, Martin Demmert, Ellinor Anna Wolf, Achim Rody, Silvio Waschina, Simon Graspeuntner, Jan Rupp, Christoph Härtel. Timing of antimicrobial prophylaxis for cesarean section is critical for gut microbiome development in term born infants.
Gut microbes.
2022 Jan; 14(1):2038855. doi:
10.1080/19490976.2022.2038855. [PMID: 35184691] - Pelle Hanberg, Mats Bue, Jesper Kabel, Andrea René Jørgensen, Christian Jessen, Kjeld Søballe, Maiken Stilling. Effects of tourniquet inflation on peri- and postoperative cefuroxime concentrations in bone and tissue.
Acta orthopaedica.
2021 Dec; 92(6):746-752. doi:
10.1080/17453674.2021.1942620. [PMID: 34334093] - Sanaa M F Gad El-Rab, Amal A Ashour, Sakeenabi Basha, Amal Ahmed Alyamani, Nayef H Felemban, Enas Tawfik Enan. Well-Orientation Strategy Biosynthesis of Cefuroxime-Silver Nanoantibiotic for Reinforced Biodentine™ and Its Dental Application against Streptococcus mutans.
Molecules (Basel, Switzerland).
2021 Nov; 26(22):. doi:
10.3390/molecules26226832. [PMID: 34833924] - Verónica Hernandis, Elisa Escudero, Ana Pareja, Pedro Marín. A fast, cost-saving and sensitive method for determination of cefuroxime in plasma by HPLC with ultraviolet detection.
Biomedical chromatography : BMC.
2021 Oct; 35(10):e5188. doi:
10.1002/bmc.5188. [PMID: 34081795] - Ashimiyu B Durojaiye, John-Ross D Clarke, George A Stamatiades, Can Wang. Repurposing cefuroxime for treatment of COVID-19: a scoping review of in silico studies.
Journal of biomolecular structure & dynamics.
2021 Aug; 39(12):4547-4554. doi:
10.1080/07391102.2020.1777904. [PMID: 32538276] - Ke Xu Szeto, Maxime Le Merdy, Benjamin Dupont, Michael B Bolger, Viera Lukacova. PBPK Modeling Approach to Predict the Behavior of Drugs Cleared by Kidney in Pregnant Subjects and Fetus.
The AAPS journal.
2021 06; 23(4):89. doi:
10.1208/s12248-021-00603-y. [PMID: 34169370] - A R Jørgensen, P Hanberg, M Bue, M B Thomassen, N Pedersen Jørgensen, M Stilling. Double-dose cefuroxime concentrations in bone, synovial fluid of the knee joint and subcutaneous adipose tissue-A randomised porcine microdialysis study.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2021 May; 160(?):105754. doi:
10.1016/j.ejps.2021.105754. [PMID: 33582285] - Martin Děrgel, Martin Voborník, Marek Pojar, Mikita Karalko, Jan Gofus, Věra Radochová, Šárka Studená, Jana Maláková, Zdeněk Turek, Jaroslav Chládek, Jiří Manďák. Lung Collapse during Mini-Thoracotomy Reduces Penetration of Cefuroxime to the Tissue: Interstitial Microdialysis Study in Animal Models.
Surgical infections.
2021 Apr; 22(3):283-291. doi:
10.1089/sur.2019.273. [PMID: 32633629] - Christer Rimmler, Christian Lanckohr, Miriam Mittrup, Henryk Welp, Gudrun Würthwein, Dagmar Horn, Manfred Fobker, Björn Ellger, Georg Hempel. Population pharmacokinetic evaluation of cefuroxime in perioperative antibiotic prophylaxis during and after cardiopulmonary bypass.
British journal of clinical pharmacology.
2021 03; 87(3):1486-1498. doi:
10.1111/bcp.14556. [PMID: 32959896] - Xiufang Liang, Zhongping Gou, Xiandi Wang, Yongsheng Wang, Jiao Yue, Na Li, Ping Feng, Yongping Qin, Jiancheng Zeng. Simultaneous quantification of cefuroxime and clindamycin in human lumbar anulus fibrosus, nucleus pulposus and serum via UPLC-MS/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2021 Feb; 1165(?):122522. doi:
10.1016/j.jchromb.2021.122522. [PMID: 33545501] - Paul Skorup, Lisa Maudsdotter, Miklós Lipcsey, Anders Larsson, Jan Sjölin. Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model.
Critical care (London, England).
2020 11; 24(1):646. doi:
10.1186/s13054-020-03303-9. [PMID: 33189146] - L Ordoñez-Boschetti, C M Torres-Romero, M J Ortiz de Leo. [Associated posterior reversible encephalopathy syndrome (PRES) to SARS-CoV-2. Case report].
Neurologia (Barcelona, Spain).
2020 Nov; 35(9):696-698. doi:
10.1016/j.nrl.2020.08.001. [PMID: 32896464] - Edurne Peña-Mendizabal, Sergi Morais, Ángel Maquieira. Neo-antigens for the serological diagnosis of IgE-mediated drug allergic reactions to antibiotics cephalosporin, carbapenem and monobactam.
Scientific reports.
2020 09; 10(1):16037. doi:
10.1038/s41598-020-73109-w. [PMID: 32994501] - Christina A Sutherland, David P Nicolau. Development of an HPLC Method for the Determination of Meropenem/Vaborbactam in Biological and Aqueous Matrixes.
Journal of chromatographic science.
2020 Aug; 58(8):726-730. doi:
10.1093/chromsci/bmaa041. [PMID: 32685976] - Pelle Hanberg, Mats Bue, Andrea René Jørgensen, Maja Thomassen, Kristina Öbrink-Hansen, Kjeld Søballe, Maiken Stilling. Pharmacokinetics of double-dose cefuroxime in porcine intervertebral disc and vertebral cancellous bone-a randomized microdialysis study.
The spine journal : official journal of the North American Spine Society.
2020 08; 20(8):1327-1332. doi:
10.1016/j.spinee.2020.03.006. [PMID: 32194245] - Ling Song, Zhiheng Yu, Yifan Xu, Xiaobei Li, Xuanlin Liu, Dongyang Liu, Tianyan Zhou. Preliminary physiologically based pharmacokinetic modeling of renally cleared drugs in Chinese pregnant women.
Biopharmaceutics & drug disposition.
2020 Jun; 41(6):248-267. doi:
10.1002/bdd.2243. [PMID: 32520400] - Sharon Akinpelu, Abraham Ajayi, Stella I Smith, Adeyemi I Adeleye. Efflux pump activity, biofilm formation and antibiotic resistance profile of Klebsiella spp. isolated from clinical samples at Lagos University Teaching Hospital.
BMC research notes.
2020 May; 13(1):258. doi:
10.1186/s13104-020-05105-2. [PMID: 32456668] - Gabriela A Albarellos, Sabrina M Passini, Martín P Lupi, Silvia Aramayona, Paula M Lorenzini, Laura Montoya, Maria F Landoni. Effect of food on the pharmacokinetics of oral cefuroxime axetil in dogs.
Journal of veterinary pharmacology and therapeutics.
2020 May; 43(3):297-302. doi:
10.1111/jvp.12854. [PMID: 32157713] - Fei Song, Chuan Liu, Junyong Zhang, Yusheng Lei, Zili Hu. Antibacterial effect of fosfomycin tromethamine on the bacteria inside urinary infection stones.
International urology and nephrology.
2020 Apr; 52(4):645-654. doi:
10.1007/s11255-019-02358-0. [PMID: 31832876] - Ravi Kumar Jairam, Sadanand R Mallurwar, Bhavesh B Gabani, Ashok Zakkula, Vinay Kiran, Sreekanth Dittakavi, Suresh P Sulochana, Zainuddin Mohd, Nuggehally R Srinivas, Ramesh Mullangi. Uptake and pharmacokinetics of cefuroxime in rabbits after intravitreal, intracameral, and topical dosing: relevance to human ocular injection of cefuroxime.
Xenobiotica; the fate of foreign compounds in biological systems.
2020 Mar; 50(3):339-345. doi:
10.1080/00498254.2019.1624872. [PMID: 31144563] - Joost J van Raaij, Noortje J D Mabelis, Kimberly N Shudofsky, Sjoerd D Meenks, Jos L M L le Noble, Paddy K C Janssen. Quantification of total and unbound cefuroxime in plasma by ultra-performance liquid chromatography tandem mass spectrometry in a cohort of critically ill patients with hypoalbuminemia and renal failure.
Journal of clinical laboratory analysis.
2020 Mar; 34(3):e23100. doi:
10.1002/jcla.23100. [PMID: 31785116] - Subramanian Swaminathan, Gifty Immanuel, Sanjay Arora, Suyog Mehta, Rajan Mittal, Amey Mane, Sujeet Narayan Charugulla. Susceptibility Pattern of Doxycycline in Comparison to Azithromycin, Cefuroxime and Amoxicillin against Common Isolates: A Retrospective Study Based on Diagnostic Laboratory Data.
The Journal of the Association of Physicians of India.
2020 Mar; 68(3):59-63. doi:
. [PMID: 32138486] - Sara Thønnings, Klaus S Jensen, Ninna B Nielsen, Martin Skjønnemand, Dennis S Hansen, Kai H W Lange, Niels Frimodt-Møller. Cefuroxime pharmacokinetics and pharmacodynamics for intravenous dosage regimens with 750 mg or 1500 mg doses in healthy young volunteers.
Journal of medical microbiology.
2020 Mar; 69(3):387-395. doi:
10.1099/jmm.0.001138. [PMID: 31958049] - Ulrich Gergs, Lina Becker, Richard Okoniewski, Michael Weiss, Karl-Stefan Delank, Joachim Neumann. Population pharmacokinetics of cefuroxime and uptake into hip and spine bone of patients undergoing orthopaedic surgery.
The Journal of pharmacy and pharmacology.
2020 Mar; 72(3):364-370. doi:
10.1111/jphp.13214. [PMID: 31858616] - Fikret Türkan, Zübeyir Huyut, Yıldıray Basbugan, İlhami Gülçin. Influence of some β-lactam drugs on selected antioxidant enzyme and lipid peroxidation levels in different rat tissues.
Drug and chemical toxicology.
2020 Jan; 43(1):27-36. doi:
10.1080/01480545.2019.1608230. [PMID: 31060396] - Christer Rimmler, Christian Lanckohr, Ceren Akamp, Dagmar Horn, Manfred Fobker, Karsten Wiebe, Bassam Redwan, Bjoern Ellger, Robin Koeck, Georg Hempel. Physiologically based pharmacokinetic evaluation of cefuroxime in perioperative antibiotic prophylaxis.
British journal of clinical pharmacology.
2019 12; 85(12):2864-2877. doi:
10.1111/bcp.14121. [PMID: 31487057] - Mikkel Tøttrup, Kjeld Søballe, Bo M Bibby, Tore F Hardlei, Peter Hansen, Kurt Fuursted, Hanne Birke-Sørensen, Mats Bue. Bone, subcutaneous tissue and plasma pharmacokinetics of cefuroxime in total knee replacement patients - a randomized controlled trial comparing continuous and short-term infusion.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
2019 Dec; 127(12):779-788. doi:
10.1111/apm.12996. [PMID: 31515843] - Hanadi H Alrammaal, Hannah K Batchelor, R Katie Morris, Hsu P Chong. Efficacy of perioperative cefuroxime as a prophylactic antibiotic in women requiring caesarean section: A systematic review.
European journal of obstetrics, gynecology, and reproductive biology.
2019 Nov; 242(?):71-78. doi:
10.1016/j.ejogrb.2019.08.022. [PMID: 31569027] - Michael Owusu, Godfred Acheampong, Augustina Annan, Kwadwo Sarfo Marfo, Isaac Osei, John Amuasi, Nimako Sarpong, Justin Im, Ondari D Mogeni, Hsin-Ying Chiang, Chih-Horng Kuo, Hyon Jin Jeon, Ursula Panzner, Se Eun Park, Florian Marks, Ellis Owusu-Dabo, Yaw Adu-Sarkodie. Ralstonia mannitolilytica sepsis: a case report.
Journal of medical case reports.
2019 Oct; 13(1):318. doi:
10.1186/s13256-019-2235-0. [PMID: 31653273] - Rahul Lalge, Priyanka Thipsay, Vijay Kumar Shankar, Abhijeet Maurya, Manjeet Pimparade, Suresh Bandari, Feng Zhang, S Narasimha Murthy, Michael A Repka. Preparation and evaluation of cefuroxime axetil gastro-retentive floating drug delivery system via hot melt extrusion technology.
International journal of pharmaceutics.
2019 Jul; 566(?):520-531. doi:
10.1016/j.ijpharm.2019.06.021. [PMID: 31185262] - Shamrulazhar S Kamal, Nana Hyldig, Łukasz Krych, Gorm Greisen, Karen A Krogfelt, Gitte Zachariassen, Dennis S Nielsen. Impact of Early Exposure to Cefuroxime on the Composition of the Gut Microbiota in Infants Following Cesarean Delivery.
The Journal of pediatrics.
2019 07; 210(?):99-105.e2. doi:
10.1016/j.jpeds.2019.03.001. [PMID: 31053348] - Ufuk Ozkan, Ali Akal, Kudret Ozkan, Omer Faruk Yilmaz, Fatih Mehmet Adıbelli. Investigating the effect of intracameral cefuroxime on oxidative stress and apoptosis in the rat cornea.
Arquivos brasileiros de oftalmologia.
2019 05; 82(4):322-328. doi:
10.5935/0004-2749.20190067. [PMID: 31116319] - Keso Skhirtladze-Dworschak, Doris Hutschala, Georg Reining, Peter Dittrich, Anna Bartunek, Martin Dworschak, Edda M Tschernko. Cefuroxime plasma and tissue concentrations in patients undergoing elective cardiac surgery: Continuous vs bolus application. A pilot study.
British journal of clinical pharmacology.
2019 04; 85(4):818-826. doi:
10.1111/bcp.13865. [PMID: 30636060] - Amal Tahri, Salima Daoud, Rim Kallel, Kamilia Ksouda, Tahia Boudawara, Zouheir Sahnoun. Safety assessment of cefuroxime on male reproductive system: Subacute toxicity and potential reversibility after a complete cycle of spermatogenesis and epididymal maturation in Wistar rats.
Reproductive toxicology (Elmsford, N.Y.).
2019 04; 85(?):75-82. doi:
10.1016/j.reprotox.2019.02.007. [PMID: 30797828] - Andrew Kirby, Eduardo Asín-Prieto, Flora Agnes Burns, Duncan Ewin, Kavi Fatania, Mithun Kailavasan, Saira Nisar, Agamemnon Pericleous, Iñaki F Trocóniz, Dermot Burke. Colo-Pro: a pilot randomised controlled trial to compare standard bolus-dosed cefuroxime prophylaxis to bolus-continuous infusion-dosed cefuroxime prophylaxis for the prevention of infections after colorectal surgery.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
2019 Feb; 38(2):357-363. doi:
10.1007/s10096-018-3435-z. [PMID: 30519893] - Yanqiu Liu, Hong Gao, Guilong Wang, Li An, Jing Yi, Xiaokui Fu, Chunlei Wen, Zijun Wang. A Comparison of the Effect of Sevoflurane and Propofol on Ventricular Repolarisation after Preoperative Cefuroxime Infusion.
BioMed research international.
2019; 2019(?):8978906. doi:
10.1155/2019/8978906. [PMID: 30719450] - Bruna Gomes, Nicolas A Geis, Florian Leuschner, Benjamin Meder, Mathias Konstandin, Hugo A Katus, Raffi Bekeredjian. Periprocedural antibiotic treatment in transvascular aortic valve replacement.
Journal of interventional cardiology.
2018 Dec; 31(6):885-890. doi:
10.1111/joic.12567. [PMID: 30397939] - Di Yan, Timea Frosch, Jens Kobelke, Jörg Bierlich, Jürgen Popp, Mathias W Pletz, Torsten Frosch. Fiber-Enhanced Raman Sensing of Cefuroxime in Human Urine.
Analytical chemistry.
2018 11; 90(22):13243-13248. doi:
10.1021/acs.analchem.8b01355. [PMID: 30387601] - Ralph Gertler, Michael Gruber, Gunther Wiesner, Stanislas Grassin-Delyle, Saïk Urien, Peter Tassani-Prell, Klaus Martin. Pharmacokinetics of cefuroxime in infants and neonates undergoing cardiac surgery.
British journal of clinical pharmacology.
2018 09; 84(9):2020-2028. doi:
10.1111/bcp.13632. [PMID: 29761538] - Adam Tucker, Paul Hegarty, Paul J Magill, Janine Blaney, Lynne V Armstrong, John E McCaffrey, David E Beverland. Acute Kidney Injury After Prophylactic Cefuroxime and Gentamicin in Patients Undergoing Primary Hip and Knee Arthroplasty-A Propensity Score-Matched Study.
The Journal of arthroplasty.
2018 09; 33(9):3009-3015. doi:
10.1016/j.arth.2018.04.044. [PMID: 29807788] - Jesús Rodríguez-Lozano, Ana de Malet, María Eliecer Cano, Luis de la Rubia, Reinhard Wallmann, Luis Martínez-Martínez, Jorge Calvo. Antimicrobial susceptibility of microorganisms that cause urinary tract infections in pediatric patients.
Enfermedades infecciosas y microbiologia clinica (English ed.).
2018 Aug; 36(7):417-422. doi:
10.1016/j.eimc.2017.08.003. [PMID: 28993064] - Paul Skorup, Lisa Maudsdotter, Eva Tano, Miklós Lipcsey, Markus Castegren, Anders Larsson, Jan Sjölin. Dynamics of Endotoxin, Inflammatory Variables, and Organ Dysfunction After Treatment With Antibiotics in an Escherichia coli Porcine Intensive Care Sepsis Model.
Critical care medicine.
2018 07; 46(7):e634-e641. doi:
10.1097/ccm.0000000000003139. [PMID: 29595561] - Ronny Langenhan, Stefanie Bushuven, Niklas Reimers, Axel Probst. Peri-operative antibiotic treatment of bacteriuria reduces early deep surgical site infections in geriatric patients with proximal femur fracture.
International orthopaedics.
2018 04; 42(4):741-746. doi:
10.1007/s00264-017-3708-7. [PMID: 29224055] - Maria Daniel, Hania Szajewska, Małgorzata Pańczyk-Tomaszewska. 7-day compared with 10-day antibiotic treatment for febrile urinary tract infections in children: protocol of a randomised controlled trial.
BMJ open.
2018 03; 8(3):e019479. doi:
10.1136/bmjopen-2017-019479. [PMID: 29500209] - Fikret Türkan, Zübeyir Huyut, Parham Taslimi, İlhami Gülçin. The in vivo effects of cefazolin, cefuroxime, and cefoperazon on the carbonic anhydrase in different rat tissues.
Journal of biochemical and molecular toxicology.
2018 Mar; 32(3):e22041. doi:
10.1002/jbt.22041. [PMID: 29457666] - Bülent Şengül, Şükrü Beydemir. The interactions of cephalosporins on polyol pathway enzymes from sheep kidney.
Archives of physiology and biochemistry.
2018 Feb; 124(1):35-44. doi:
10.1080/13813455.2017.1358749. [PMID: 28758816] - A Hosmann, L C Ritscher, H Burgmann, Z Oesterreicher, W Jäger, S Poschner, E Knosp, A Reinprecht, A Gruber, M Zeitlinger. Concentrations of Cefuroxime in Brain Tissue of Neurointensive Care Patients.
Antimicrobial agents and chemotherapy.
2018 02; 62(2):. doi:
10.1128/aac.02164-17. [PMID: 29203481] - Farid Ahmed, Samina Perveen, Kiramat Shah, Muhammad Raza Shah, Shakil Ahmed. Synthesis and characterization of triazole based supramolecule for interaction with cefuroxime in tap water and blood plasma.
Ecotoxicology and environmental safety.
2018 Jan; 147(?):49-54. doi:
10.1016/j.ecoenv.2017.08.023. [PMID: 28826030] - Siti Norhawani Harun, Syafinaz Amin Nordin, Siti Salwa Abd Gani, Ahmad Fuad Shamsuddin, Mahiran Basri, Hamidon Bin Basri. Development of nanoemulsion for efficient brain parenteral delivery of cefuroxime: designs, characterizations, and pharmacokinetics.
International journal of nanomedicine.
2018; 13(?):2571-2584. doi:
10.2147/ijn.s151788. [PMID: 29731632] - André Dallmann, Ibrahim Ince, Juri Solodenko, Michaela Meyer, Stefan Willmann, Thomas Eissing, Georg Hempel. Physiologically Based Pharmacokinetic Modeling of Renally Cleared Drugs in Pregnant Women.
Clinical pharmacokinetics.
2017 12; 56(12):1525-1541. doi:
10.1007/s40262-017-0538-0. [PMID: 28391404] - R Schwameis, S Syré, D Marhofer, A Appelt, D Burau, K Sarahrudi, C Kloft, M Zeitlinger. Pharmacokinetics of Cefuroxime in Synovial Fluid.
Antimicrobial agents and chemotherapy.
2017 10; 61(10):. doi:
10.1128/aac.00992-17. [PMID: 28784675] - Evaggelos Kiriazopoulos, Sabina Zaharaki, Ariadni Vonaparti, Panagiota Vourna, Eirini Panteri-Petratou, Dimitra Gennimata, Kara Lombardo, Irene Panderi. Quantification of three beta-lactam antibiotics in breast milk and human plasma by hydrophilic interaction liquid chromatography/positive-ion electrospray ionization mass spectrometry.
Drug testing and analysis.
2017 Jul; 9(7):1062-1072. doi:
10.1002/dta.2104. [PMID: 27714984] - R Bruch, C Chatelle, A Kling, B Rebmann, S Wirth, S Schumann, W Weber, C Dincer, G Urban. Clinical on-site monitoring of ß-lactam antibiotics for a personalized antibiotherapy.
Scientific reports.
2017 06; 7(1):3127. doi:
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Journal of infection and public health.
2017 May; 10(3):353-356. doi:
10.1016/j.jiph.2016.08.012. [PMID: 27614577] - Marko Tapani Ristola, Eliisa Löyttyniemi, Timo Hurme. Factors Associated with Abnormal Imaging and Infection Recurrence after a First Febrile Urinary Tract Infection in Children.
European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie.
2017 Apr; 27(2):142-149. doi:
10.1055/s-0036-1572418. [PMID: 26855368] - Tetyana O Kryuchko, Vira P Kharshman, Inna M Nesina, Nataliia V Kuzmenko, Jaroslava M Oleksiienko. Regional features of the microbial landscape of urine and comparative evaluation of antimicrobial therapy in children with cystitis.
Wiadomosci lekarskie (Warsaw, Poland : 1960).
2017 ; 70(3 pt 2):566-570. doi:
. [PMID: 28713083] - Lutz Hilker, Thomas von Woedtke, Klaus Dieter Weltmann, Hans-Georg Wollert. Cold atmospheric plasma: a new tool for the treatment of superficial driveline infections.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.
2017 Jan; 51(1):186-187. doi:
10.1093/ejcts/ezw212. [PMID: 27354253] - D G H A van Dam, D M T Burgers, N Foudraine, P K C Janssen, C Neef, J L M L le Noble. Treatment of cefuroxime-induced neurotoxicity with continuous venovenous haemofiltration.
The Netherlands journal of medicine.
2017 Jan; 75(1):32-34. doi:
NULL. [PMID: 28124668] - Paddy K C Janssen, Norbert A Foudraine, Desirée M T Burgers, Kees Neef, Jos L M L le Noble. Population Pharmacokinetics of Cefuroxime in Critically Ill Patients Receiving Continuous Venovenous Hemofiltration With Regional Citrate Anticoagulation and a Phosphate-Containing Replacement Fluid.
Therapeutic drug monitoring.
2016 12; 38(6):699-705. doi:
10.1097/ftd.0000000000000330. [PMID: 27494946] - G Zachariassen, N Hyldig, J S Joergensen, D S Nielsen, G Greisen. The half-life and exposure of cefuroxime varied in newborn infants after a Caesarean section.
Acta paediatrica (Oslo, Norway : 1992).
2016 Sep; 105(9):1074-8. doi:
10.1111/apa.13489. [PMID: 27240549] - T Hüsch, V Rheinboldt, A Thalhammer, T Müller, A Haferkamp. [Emphysematous cystitis].
Der Urologe. Ausg. A.
2016 May; 55(5):645-7. doi:
10.1007/s00120-016-0080-y. [PMID: 27119961] - Zijian Gong, Wei Lai, Min Liu, Zhengshuang Hua, Yayin Sun, Qingfang Xu, Yue Xia, Yue Zhao, Xiaoyuan Xie. Novel Genes Related to Ceftriaxone Resistance Found among Ceftriaxone-Resistant Neisseria gonorrhoeae Strains Selected In Vitro.
Antimicrobial agents and chemotherapy.
2016 Apr; 60(4):2043-51. doi:
10.1128/aac.00149-15. [PMID: 26787702] - Mikkel Tøttrup, Mats Bue, Janne Koch, Louise Kruse Jensen, Pelle Hanberg, Bent Aalbæk, Kurt Fuursted, Henrik Elvang Jensen, Kjeld Søballe. Effects of Implant-Associated Osteomyelitis on Cefuroxime Bone Pharmacokinetics: Assessment in a Porcine Model.
The Journal of bone and joint surgery. American volume.
2016 Mar; 98(5):363-9. doi:
10.2106/jbjs.o.00550. [PMID: 26935458] - Pelle Hanberg, Mats Bue, Hanne Birke Sørensen, Kjeld Søballe, Mikkel Tøttrup. Pharmacokinetics of single-dose cefuroxime in porcine intervertebral disc and vertebral cancellous bone determined by microdialysis.
The spine journal : official journal of the North American Spine Society.
2016 Mar; 16(3):432-8. doi:
10.1016/j.spinee.2015.11.031. [PMID: 26620946] - Mladena Lalic-Popovic, Jovana Paunkovic, Zorica Grujic, Svetlana Golocorbin-Kon, Ljubomir Milasinovic, Hani Al-Salami, Momir Mikov. Decreased placental and transcellular permeation of cefuroxime in pregnant women with diabetes.
Journal of diabetes.
2016 Mar; 8(2):238-45. doi:
10.1111/1753-0407.12288. [PMID: 25800069] - G A Albarellos, L Montoya, P M Lorenzini, S M Passini, M P Lupi, M F Landoni. Pharmacokinetics of cefuroxime after intravenous, intramuscular, and subcutaneous administration to dogs.
Journal of veterinary pharmacology and therapeutics.
2016 Feb; 39(1):40-4. doi:
10.1111/jvp.12239. [PMID: 25982523] - U-Im Chang, Hyung Wook Kim, Seong-Heon Wie. Use of cefuroxime for women with community-onset acute pyelonephritis caused by cefuroxime-susceptible or -resistant Escherichia coli.
The Korean journal of internal medicine.
2016 Jan; 31(1):145-55. doi:
10.3904/kjim.2016.31.1.145. [PMID: 26767868] - Serap Süzük, Banu Kaşkatepe, Havva Avcıküçük, Sebahat Aksaray, Ahmet Başustaoğlu. [The comparison of antibiotic susceptibilities of uropathogenic Escherichia coli isolates in transition from CLSI to EUCAST].
Mikrobiyoloji bulteni.
2015 Oct; 49(4):494-501. doi:
10.5578/mb.10106. [PMID: 26649407] - Marieke Aalbers, Peter G J ter Horst, Wobbe Hospes, Michel L Hijmering, Alexander J Spanjersberg. Targeting cefuroxime plasma concentrations during coronary artery bypass graft surgery with cardiopulmonary bypass.
International journal of clinical pharmacy.
2015 Aug; 37(4):592-8. doi:
10.1007/s11096-015-0101-8. [PMID: 25791346] - Giorgio Piccinelli, Valeria Biscaro, Franco Gargiulo, Arnaldo Caruso, Maria Antonia De Francesco. Characterization and antibiotic susceptibility of Streptococcus agalactiae isolates causing urinary tract infections.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.
2015 Aug; 34(?):1-6. doi:
10.1016/j.meegid.2015.07.001. [PMID: 26144658] - Mohammad Awwad, Fuad Al-Rimawi, Khuloud Jamal Khayyat Dajani, Mustafa Khamis, Shlomo Nir, Rafik Karaman. Removal of amoxicillin and cefuroxime axetil by advanced membranes technology, activated carbon and micelle-clay complex.
Environmental technology.
2015 Jul; 36(13-16):2069-78. doi:
10.1080/09593330.2015.1019935. [PMID: 25686519] - Eduardo Asín-Prieto, Amaia Soraluce, Iñaki F Trocóniz, Eugenia Campo Cimarras, Jaione Sáenz de Ugarte Sobrón, Alicia Rodríguez-Gascón, Arantxazu Isla. Population pharmacokinetic models for cefuroxime and metronidazole used in combination as prophylactic agents in colorectal surgery: Model-based evaluation of standard dosing regimens.
International journal of antimicrobial agents.
2015 May; 45(5):504-11. doi:
10.1016/j.ijantimicag.2015.01.008. [PMID: 25758019] - Fusun Can, Ozlem Kurt Azap, Ceren Seref, Pelin Ispir, Hande Arslan, Onder Ergonul. Emerging Escherichia coli O25b/ST131 clone predicts treatment failure in urinary tract infections.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2015 Feb; 60(4):523-7. doi:
10.1093/cid/ciu864. [PMID: 25378460] - Marcin Stobiecki, Małgorzata Sacha, Ewa Czarnobilska. [Anaphylaxis as part of a clinical diagnosis of mastocytosi - case demonstration].
Przeglad lekarski.
2015; 72(12):783-6. doi:
NULL. [PMID: 27024961] - Sruti Jammula, Ch Niranjan Patra, Suryakanta Swain, Kanhu Charan Panigrahi, Sabita Nayak, Subas Chandra Dinda, Muddana Eswara Bhanoji Rao. Design and characterization of cefuroxime axetil biphasic floating minitablets.
Drug delivery.
2015 Jan; 22(1):125-35. doi:
10.3109/10717544.2013.871603. [PMID: 24417642] - Mikkel Tøttrup, Bo M Bibby, Tore F Hardlei, Mats Bue, Sigrid Kerrn-Jespersen, Kurt Fuursted, Kjeld Søballe, Hanne Birke-Sørensen. Continuous versus short-term infusion of cefuroxime: assessment of concept based on plasma, subcutaneous tissue, and bone pharmacokinetics in an animal model.
Antimicrobial agents and chemotherapy.
2015 Jan; 59(1):67-75. doi:
10.1128/aac.03857-14. [PMID: 25313214] - Jennifer H Huang, Rachel Sunstrom, Myrna Y Munar, Ganesh Cherala, Arthur Legg, Ali J Olyeai, Stephen M Langley. Are children undergoing cardiac surgery receiving antibiotics at subtherapeutic levels?.
The Journal of thoracic and cardiovascular surgery.
2014 Oct; 148(4):1591-6. doi:
10.1016/j.jtcvs.2013.12.043. [PMID: 24521951] - Bhupender Singh, Parameswara Rao Vuddanda, Vijayakumar M R, Vinod Kumar, Preeti S Saxena, Sanjay Singh. Cefuroxime axetil loaded solid lipid nanoparticles for enhanced activity against S. aureus biofilm.
Colloids and surfaces. B, Biointerfaces.
2014 Sep; 121(?):92-8. doi:
10.1016/j.colsurfb.2014.03.046. [PMID: 24945607] - Mikkel Tøttrup, Tore Forsingdal Hardlei, Michael Bendtsen, Mats Bue, Birgitte Brock, Kurt Fuursted, Kjeld Søballe, Hanne Birke-Sørensen. Pharmacokinetics of cefuroxime in porcine cortical and cancellous bone determined by microdialysis.
Antimicrobial agents and chemotherapy.
2014 Jun; 58(6):3200-5. doi:
10.1128/aac.02438-14. [PMID: 24663019] - Siiri Kõljalg, Kai Truusalu, Jelena Stsepetova, Kristiine Pai, Inga Vainumäe, Epp Sepp, Marika Mikelsaar. The Escherichia coli phylogenetic group B2 with integrons prevails in childhood recurrent urinary tract infections.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
2014 May; 122(5):452-8. doi:
10.1111/apm.12167. [PMID: 24033434] - S Craxford, E Bayley, M Needoff. Antibiotic-associated complications following lower limb arthroplasty: a comparison of two prophylactic regimes.
European journal of orthopaedic surgery & traumatology : orthopedie traumatologie.
2014 May; 24(4):539-43. doi:
10.1007/s00590-013-1348-1. [PMID: 24178085] - M L van der Vusse, W J van Son, A Ott, W Manson. Helicobacter canis bacteremia in a renal transplant patient.
Transplant infectious disease : an official journal of the Transplantation Society.
2014 Feb; 16(1):125-9. doi:
10.1111/tid.12174. [PMID: 24372779] - A D Ross, P J Boscainos, A Malhas, C Wigderowitz. Peri-operative renal morbidity secondary to gentamicin and flucloxacillin chemoprophylaxis for hip and knee arthroplasty.
Scottish medical journal.
2013 Nov; 58(4):209-12. doi:
10.1177/0036933013507850. [PMID: 24215038] - Daphne Bertholee, Peter G J ter Horst, Michel L Hijmering, Alexander J Spanjersberg, Wobbe Hospes, Bob Wilffert. Blood concentrations of cefuroxime in cardiopulmonary bypass surgery.
International journal of clinical pharmacy.
2013 Oct; 35(5):798-804. doi:
10.1007/s11096-013-9810-z. [PMID: 23794078] - C R Debnath, M R Debnath, N Nabi, N A Khan, S Chakraborty. A case of Gaucher's disease progressing to liver cirrhosis.
Mymensingh medical journal : MMJ.
2013 Apr; 22(2):394-6. doi:
". [PMID: 23715368] - I M Cullen, R P Manecksha, E McCullagh, S Ahmad, F O'Kelly, R Flynn, T E D McDermott, P Murphy, R Grainger, J P Fennell, J A Thornhill. An 11-year analysis of the prevalent uropathogens and the changing pattern of Escherichia coli antibiotic resistance in 38,530 community urinary tract infections, Dublin 1999-2009.
Irish journal of medical science.
2013 Mar; 182(1):81-9. doi:
10.1007/s11845-012-0834-5. [PMID: 22669684] - Yuan-Pin Hung, Hsiao-Ju Lin, Tai-Chieh Wu, Hsiu-Chuan Liu, Jen-Chieh Lee, Chih-I Lee, Yi-Hui Wu, Lei Wan, Pei-Jane Tsai, Wen-Chien Ko. Risk factors of fecal toxigenic or non-toxigenic Clostridium difficile colonization: impact of Toll-like receptor polymorphisms and prior antibiotic exposure.
PloS one.
2013; 8(7):e69577. doi:
10.1371/journal.pone.0069577. [PMID: 23936050] - Mahir Seyrek, Murat Binbay, Emrah Yuruk, Tolga Akman, Rahmi Aslan, Ozgur Yazici, Yalcin Berberoglu, Ahmet Y Muslumanoglu. Perioperative prophylaxis for percutaneous nephrolithotomy: randomized study concerning the drug and dosage.
Journal of endourology.
2012 Nov; 26(11):1431-6. doi:
10.1089/end.2012.0242. [PMID: 22612061] - Long-shan Zhao, Ran Yin, Bin-bin Wei, Qing Li, Zhen-yuan Jiang, Xiao-hui Chen, Kai-shun Bi. Comparative pharmacokinetics of cefuroxime lysine after single intravenous, intraperitoneal, and intramuscular administration to rats.
Acta pharmacologica Sinica.
2012 Nov; 33(11):1348-52. doi:
10.1038/aps.2012.99. [PMID: 23064723] - Fabiana Ferreira, Silvia Santos, Jorge Nascimento, Tânia Strabelli, Maria Carmona. Influence of cardiopulmonary bypass on cefuroxime plasma concentration and pharmacokinetics in patients undergoing coronary surgery.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.
2012 Aug; 42(2):300-5. doi:
10.1093/ejcts/ezr319. [PMID: 22290920] - Longshan Zhao, Qing Li, Wei Yang, Bosai He, Binbin Wei, Ran Liu, Jingjing Liu, Xiaohui Chen, Kaishun Bi. [Determination of cefuroxime in liver-injured rat plasma by ultra fast liquid chromatography-tandem mass spectrometry via acidified protein precipitation].
Se pu = Chinese journal of chromatography.
2012 Jul; 30(7):705-10. doi:
10.3724/sp.j.1123.2012.03001. [PMID: 23189666] - Gregory Venetis, Kalliopi Chatzika, Georgia Pitsiou, Nikolaos Kechagias, Kostas Antoniades, Ioannis P Kioumis. Saliva and blood concentration of cefuroxime in patients undergoing maxillofacial surgery.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.
2012 Jun; 70(6):1398-403. doi:
10.1016/j.joms.2012.01.007. [PMID: 22459228] - Ahmet Emre Eskazan, Ayse Salihoglu, Emine Gulturk, Seniz Ongoren, Teoman Soysal. Thrombotic thrombocytopenic purpura after prophylactic cefuroxime axetil administered in relation to a liposuction procedure.
Aesthetic plastic surgery.
2012 Apr; 36(2):464-7. doi:
10.1007/s00266-011-9794-9. [PMID: 21853406] - Yong Heon Lee, Anthony W Kingston, John D Helmann. Glutamate dehydrogenase affects resistance to cell wall antibiotics in Bacillus subtilis.
Journal of bacteriology.
2012 Mar; 194(5):993-1001. doi:
10.1128/jb.06547-11. [PMID: 22178969]