Fusidate Sodium (BioDeep_00000015174)
PANOMIX_OTCML-2023
代谢物信息卡片
Fusidic acid (sodium salt)
化学式: C31H47NaO6 (538.3270162)
中文名称: 夫西地酸钠
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 56.32%
分子结构信息
SMILES: CC1C2CCC3(C(C2(CCC1O)C)C(CC4C3(CC(C4=C(CCC=C(C)C)C(=O)[O-])OC(=O)C)C)O)C.[Na+]
InChI: /q
描述信息
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C254 - Anti-Infective Agent > C52588 - Antibacterial Agent
Fusidic acid sodium salt (Sodium fusidate), a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid sodium salt has no corticosteroid effects. Fusidic acid sodium salt inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome[1][2].
同义名列表
4 个代谢物同义名
Fusidic acid (sodium salt); Fusidate Sodium; Sodium fusidate; SQ-16360
数据库引用编号
8 个数据库交叉引用编号
- KEGG: C76403
- KEGGdrug: D00213
- PubChem: 23672955
- ChEMBL: CHEMBL1256987
- MeSH: Fusidic Acid
- CAS: 1394-43-0
- CAS: 751-94-0
- medchemexpress: HY-B1350A
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Haeun Kwon, Bo-Ram Jin, Sori Yoo, Hyo-Jung Kim, Bang Yeon Hwang, Yuanqiang Guo, Joung Han Yim, Il-Chan Kim, Sang Hee Shim, Hyo Jin An, Dongho Lee. New fusidane-type nortriterpenoids from the Arctic marine-derived fungus Simplicillium lamellicola culture medium with their inhibitory effect on benign prostatic hyperplasia.
Bioorganic chemistry.
2024 Feb; 143(?):107070. doi:
10.1016/j.bioorg.2023.107070. [PMID: 38190796] - Matthias Fellner, Annabel Walsh, Stephen Dela Ahator, Nadia Aftab, Ben Sutherland, Eng W Tan, Alexander T Bakker, Nathaniel I Martin, Mario van der Stelt, Christian S Lentz. Biochemical and Cellular Characterization of the Function of Fluorophosphonate-Binding Hydrolase H (FphH) in Staphylococcus aureus Support a Role in Bacterial Stress Response.
ACS infectious diseases.
2023 Oct; ?(?):. doi:
10.1021/acsinfecdis.3c00246. [PMID: 37824340] - Pinar Ili, Fikret Sari. Egg yolk oil accelerates wound healing in streptozotocin induced diabetic rats.
Biotechnic & histochemistry : official publication of the Biological Stain Commission.
2023 Feb; 98(2):94-111. doi:
10.1080/10520295.2022.2115554. [PMID: 36040350] - Jan Holmbäck, Vibhu Rinwa, Jenny Johansson, Joakim Håkansson, Puneet Rinwa, Anders Carlsson, Bengt Herslöf. Preclinical development of sodium fusidate antibiotic cutaneous spray based on water-free lipid formulation system.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2022 Sep; 176(?):106250. doi:
10.1016/j.ejps.2022.106250. [PMID: 35779822] - Mohammed Salih, Pavan Walvekar, Calvin A Omolo, Ahmed A Elrashedy, Nikita Devnarain, Victoria Fasiku, Ayman Y Waddad, Chunderika Mocktar, Thirumala Govender. A self-assembled polymer therapeutic for simultaneously enhancing solubility and antimicrobial activity and lowering serum albumin binding of fusidic acid.
Journal of biomolecular structure & dynamics.
2021 10; 39(17):6567-6584. doi:
10.1080/07391102.2020.1803140. [PMID: 32772814] - Haider N Sultani, Ibrahim Morgan, Hidayat Hussain, Andreas H Roos, Haleh H Haeri, Goran N Kaluđerović, Dariush Hinderberger, Bernhard Westermann. Access to New Cytotoxic Triterpene and Steroidal Acid-TEMPO Conjugates by Ugi Multicomponent-Reactions.
International journal of molecular sciences.
2021 Jul; 22(13):. doi:
10.3390/ijms22137125. [PMID: 34281176] - S Muralidharan, K Arun, V Ruckmani, B Devi. Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis.
Journal of postgraduate medicine.
2021 Jul; 67(3):174-176. doi:
10.4103/jpgm.jpgm_1214_20. [PMID: 34380804] - Maria Michela Lauriola, Paolo Sena, Antonio De Bitonto, Monica Corazza. Allergic Contact Dermatitis Due to 'Therapeutic Uses' of Tea Tree Oil on the Lips and Toenails.
Dermatitis : contact, atopic, occupational, drug.
2021 May; 32(3):e40-e41. doi:
10.1097/der.0000000000000649. [PMID: 33332860] - Zhi-Bin Zhang, Si-Yao Du, Bo Ji, Chang-Jiu Ji, Yi-Wen Xiao, Ri-Ming Yan, Du Zhu. New Helvolic Acid Derivatives with Antibacterial Activities from Sarocladium oryzae DX-THL3, an Endophytic Fungus from Dongxiang Wild Rice (Oryza rufipogon Griff.).
Molecules (Basel, Switzerland).
2021 Mar; 26(7):. doi:
10.3390/molecules26071828. [PMID: 33805102] - W W Huang, X Y Ge, Y Huang, X T Chai, L Zhang, Y X Zhang, L N Deng, C Q Liu, H Xu, J Gao. High-yield strain of fusidic acid obtained by atmospheric and room temperature plasma mutagenesis and the transcriptional changes involved in improving its production in fungus Fusidium coccineum.
Journal of applied microbiology.
2021 Feb; 130(2):405-415. doi:
10.1111/jam.14797. [PMID: 32734700] - Samuel K Kwofie, Emmanuel Broni, Seth O Asiedu, Gabriel B Kwarko, Bismark Dankwa, Kweku S Enninful, Elvis K Tiburu, Michael D Wilson. Cheminformatics-Based Identification of Potential Novel Anti-SARS-CoV-2 Natural Compounds of African Origin.
Molecules (Basel, Switzerland).
2021 Jan; 26(2):. doi:
10.3390/molecules26020406. [PMID: 33466743] - Kaat José Peeters, Ashley Haeck, Lies Harinck, Oluwatoyin Oluwakemi Afolabi, Kristof Demeestere, Kris Audenaert, Monica Höfte. Morphological, Pathogenic and Toxigenic Variability in the Rice Sheath Rot Pathogen Sarocladium Oryzae.
Toxins.
2020 02; 12(2):. doi:
10.3390/toxins12020109. [PMID: 32046323] - Zhi-Qin Cao, Jian-Ming Lv, Qiu Liu, Sheng-Ying Qin, Guo-Dong Chen, Ping Dai, Yue Zhong, Hao Gao, Xin-Sheng Yao, Dan Hu. Biosynthetic Study of Cephalosporin P1 Reveals a Multifunctional P450 Enzyme and a Site-Selective Acetyltransferase.
ACS chemical biology.
2020 01; 15(1):44-51. doi:
10.1021/acschembio.9b00863. [PMID: 31860257] - Mathew Njoroge, Gurminder Kaur, Marlene Espinoza-Moraga, Antonina Wasuna, Godwin Akpeko Dziwornu, Ronnett Seldon, Dale Taylor, John Okombo, Digby F Warner, Kelly Chibale. Semisynthetic Antimycobacterial C-3 Silicate and C-3/C-21 Ester Derivatives of Fusidic Acid: Pharmacological Evaluation and Stability Studies in Liver Microsomes, Rat Plasma, and Mycobacterium tuberculosis culture.
ACS infectious diseases.
2019 09; 5(9):1634-1644. doi:
10.1021/acsinfecdis.9b00208. [PMID: 31309823] - Kanika Thakur, Gajanand Sharma, Bhupinder Singh, Sanjay Chhibber, Om Prakash Katare. Nano-engineered lipid-polymer hybrid nanoparticles of fusidic acid: an investigative study on dermatokinetics profile and MRSA-infected burn wound model.
Drug delivery and translational research.
2019 08; 9(4):748-763. doi:
10.1007/s13346-019-00616-3. [PMID: 30652257] - Francesco Miconi, Nicola Principi, Lorenzo Cassiani, Federica Celi, Roberta Crispoldi, Ada Russo, Susanna Esposito, Manuela Papini. A Cheek Nodule in a Child: Be Aware of Idiopathic Facial Aseptic Granuloma and Its Differential Diagnosis.
International journal of environmental research and public health.
2019 07; 16(14):. doi:
10.3390/ijerph16142471. [PMID: 31336722] - Maxime Bataillard, Marie-Noëlle Beyens, Geneviève Mounier, Delphine Vergnon-Miszczycha, Haleh Bagheri, Pascal Cathebras. Muscle Damage Due to Fusidic Acid-Statin Interaction: Review of 75 Cases From the French Pharmacovigilance Database and Literature Reports.
American journal of therapeutics.
2019 May; 26(3):e375-e379. doi:
10.1097/mjt.0000000000000679. [PMID: 29189310] - Rita Pimenta, João Borges-Costa. Successful Treatment with Fusidic Acid in a Patient with Folliculitis Decalvans.
Acta dermatovenerologica Croatica : ADC.
2019 Mar; 27(1):49-50. doi:
. [PMID: 31032795] - Ahmad M Eid, Ibraheem Istateyeh, Noura Salhi, Thaer Istateyeh. Antibacterial Activity of Fusidic Acid and Sodium Fusidate Nanoparticles Incorporated in Pine Oil Nanoemulgel.
International journal of nanomedicine.
2019; 14(?):9411-9421. doi:
10.2147/ijn.s229557. [PMID: 31819440] - Marco Adriano Chessa, Andrea Sechi, Carlotta Baraldi, Stefania Barruscotti, Miriam Leuzzi, Carlotta Gurioli, Annalucia Virdi, Francesco Savoia, Iria Neri. Zoon's plasma cell balanitis: clinical and dermoscopic features in pediatric patients.
International journal of dermatology.
2018 11; 57(11):e142-e144. doi:
10.1111/ijd.14176. [PMID: 30117600] - Kanika Thakur, Gajanand Sharma, Bhupinder Singh, Sanjay Chhibber, A B Patil, Om Prakash Katare. Chitosan-tailored lipidic nanoconstructs of Fusidic acid as promising vehicle for wound infections: An explorative study.
International journal of biological macromolecules.
2018 Aug; 115(?):1012-1025. doi:
10.1016/j.ijbiomac.2018.04.092. [PMID: 29680503] - Jian-Ming Lv, Dan Hu, Hao Gao, Tetsuo Kushiro, Takayoshi Awakawa, Guo-Dong Chen, Chuan-Xi Wang, Ikuro Abe, Xin-Sheng Yao. Biosynthesis of helvolic acid and identification of an unusual C-4-demethylation process distinct from sterol biosynthesis.
Nature communications.
2017 11; 8(1):1644. doi:
10.1038/s41467-017-01813-9. [PMID: 29158519] - Xiaowei Luo, Xuefeng Zhou, Xiuping Lin, Xiaochu Qin, Tianyu Zhang, Junfeng Wang, Zhengchao Tu, Bin Yang, Shengrong Liao, Yongqi Tian, Xiaoyan Pang, Kumaravel Kaliyaperumal, Jian Lin Li, Huaming Tao, Yonghong Liu. Antituberculosis compounds from a deep-sea-derived fungus Aspergillus sp. SCSIO Ind09F01.
Natural product research.
2017 Aug; 31(16):1958-1962. doi:
10.1080/14786419.2016.1266353. [PMID: 28068839] - Amélie Marsot, Amelie Ménard, Julien Dupouey, Cedric Muziotti, Romain Guilhaumou, Olivier Blin. Population pharmacokinetics of rifampicin in adult patients with osteoarticular infections: interaction with fusidic acid.
British journal of clinical pharmacology.
2017 05; 83(5):1039-1047. doi:
10.1111/bcp.13178. [PMID: 27813241] - Manlu Zhu, Xiongfeng Dai, Yi-Ping Wang. Real time determination of bacterial in vivo ribosome translation elongation speed based on LacZα complementation system.
Nucleic acids research.
2016 Nov; 44(20):e155. doi:
10.1093/nar/gkw698. [PMID: 27903884] - Anshul Gupta, Jennifer J Harris, Jianrong Lin, James P Bulgarelli, Bruce K Birmingham, Scott W Grimm. Fusidic Acid Inhibits Hepatic Transporters and Metabolic Enzymes: Potential Cause of Clinical Drug-Drug Interaction Observed with Statin Coadministration.
Antimicrobial agents and chemotherapy.
2016 10; 60(10):5986-94. doi:
10.1128/aac.01335-16. [PMID: 27458210] - Ben Knippenberg, Madhu Page-Sharp, Sam Salman, Ben Clark, John Dyer, Kevin T Batty, Timothy M E Davis, Laurens Manning. Validation and Application of a Dried Blood Spot Assay for Biofilm-Active Antibiotics Commonly Used for Treatment of Prosthetic Implant Infections.
Antimicrobial agents and chemotherapy.
2016 08; 60(8):4940-55. doi:
10.1128/aac.00756-16. [PMID: 27270283] - War War May Zin, Suradet Buttachon, Tida Dethoup, Carla Fernandes, Sara Cravo, Madalena M M Pinto, Luís Gales, José A Pereira, Artur M S Silva, Nazim Sekeroglu, Anake Kijjoa. New Cyclotetrapeptides and a New Diketopiperzine Derivative from the Marine Sponge-Associated Fungus Neosartorya glabra KUFA 0702.
Marine drugs.
2016 Jul; 14(7):. doi:
10.3390/md14070136. [PMID: 27447650] - G Girolomoni, R Mattina, S Manfredini, S Vertuani, G Fabrizi. Fusidic acid betamethasone lipid cream.
International journal of clinical practice.
2016 May; 70 Suppl 184(?):4-13. doi:
10.1111/ijcp.12808. [PMID: 27121235] - Heather Eng, Renato J Scialis, Charles J Rotter, Jian Lin, Sarah Lazzaro, Manthena V Varma, Li Di, Bo Feng, Michael West, Amit S Kalgutkar. The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide-Mediated Hepatic Clearance and May Potentiate Statin-Induced Myopathy.
Drug metabolism and disposition: the biological fate of chemicals.
2016 May; 44(5):692-9. doi:
10.1124/dmd.115.067447. [PMID: 26888941] - Shailaja Hittalmani, H B Mahesh, Channappa Mahadevaiah, Mothukapalli Krishnareddy Prasannakumar. De novo genome assembly and annotation of rice sheath rot fungus Sarocladium oryzae reveals genes involved in Helvolic acid and Cerulenin biosynthesis pathways.
BMC genomics.
2016 Mar; 17(?):271. doi:
10.1186/s12864-016-2599-0. [PMID: 27036298] - M Corazza, A Virgili, S Minghetti, G Toni, A Borghi. Dermoscopy in plasma cell balanitis: its usefulness in diagnosis and follow-up.
Journal of the European Academy of Dermatology and Venereology : JEADV.
2016 Jan; 30(1):182-4. doi:
10.1111/jdv.12692. [PMID: 25176141] - K Bachoumas, M Fiancette, J-B Lascarrou, J-C Lacherade, F Leclair, J Reignier. Fatal rhabdomyolysis following the co-prescription of fusidic acid and pravastatin.
Medecine et maladies infectieuses.
2015 Oct; 45(10):417-9. doi:
10.1016/j.medmal.2015.09.006. [PMID: 26472060] - Jasper Fuk-Woo Chan, Maggie Kam-Man Ma, Gavin Shueng-Wai Chan, Gary Chi-Wang Chan, Garnet Kwan-Yue Choi, Kwok-Hung Chan, Vincent Chi-Chung Cheng, Kwok-Wah Chan, Bo-Ying Choy, Kwok-Yung Yuen. Rapid reduction of viruria and stabilization of allograft function by fusidic acid in a renal transplant recipient with JC virus-associated nephropathy.
Infection.
2015 Oct; 43(5):577-81. doi:
10.1007/s15010-015-0721-x. [PMID: 25944568] - Takuma Suematsu, Osamu Watanabe, Kiyoshi Kita, Shin-ichi Yokobori, Yoh-ichi Watanabe. Arabidopsis thaliana mitochondrial EF-G1 functions in two different translation steps.
Journal of biochemistry.
2014 Feb; 155(2):107-14. doi:
10.1093/jb/mvt105. [PMID: 24272752] - Carina Vingsbo Lundberg, Niels Frimodt-Møller. Efficacy of topical and systemic antibiotic treatment of meticillin-resistant Staphylococcus aureus in a murine superficial skin wound infection model.
International journal of antimicrobial agents.
2013 Sep; 42(3):272-5. doi:
10.1016/j.ijantimicag.2013.05.008. [PMID: 23837927] - Ming Zhao, Tanja Gödecke, Jordan Gunn, Jin-Ao Duan, Chun-Tao Che. Protostane and fusidane triterpenes: a mini-review.
Molecules (Basel, Switzerland).
2013 Apr; 18(4):4054-80. doi:
10.3390/molecules18044054. [PMID: 23563857] - Jürgen B Bulitta, Olanrewaju O Okusanya, Alan Forrest, Sujata M Bhavnani, Kay Clark, J Gordon Still, Prabhavathi Fernandes, Paul G Ambrose. Population pharmacokinetics of fusidic acid: rationale for front-loaded dosing regimens due to autoinhibition of clearance.
Antimicrobial agents and chemotherapy.
2013 Jan; 57(1):498-507. doi:
10.1128/aac.01354-12. [PMID: 23147726] - Jianglin Zhao, Yan Mou, Tijiang Shan, Yan Li, Shiqiong Lu, Ligang Zhou. Preparative separation of helvolic acid from the endophytic fungus Pichia guilliermondii Ppf9 by high-speed counter-current chromatography.
World journal of microbiology & biotechnology.
2012 Mar; 28(3):835-40. doi:
10.1007/s11274-011-0878-0. [PMID: 22805802] - Yuhta Nomura, Taito Takabayashi, Hiroshi Kuroda, Yasushi Yukawa, Kwanchanok Sattasuk, Mitsuru Akita, Akira Nozawa, Yuzuru Tozawa. ppGpp inhibits peptide elongation cycle of chloroplast translation system in vitro.
Plant molecular biology.
2012 Jan; 78(1-2):185-96. doi:
10.1007/s11103-011-9858-x. [PMID: 22108865] - J Gordon Still, Kay Clark, Thorsten P Degenhardt, Drusilla Scott, Prabhavathi Fernandes, Maria J Gutierrez. Pharmacokinetics and safety of single, multiple, and loading doses of fusidic acid in healthy subjects.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2011 Jun; 52 Suppl 7(?):S504-12. doi:
10.1093/cid/cir174. [PMID: 21546627] - Georg Isbary, Gregor Morfill, Julia Zimmermann, Tetsuji Shimizu, Wilhelm Stolz. Cold atmospheric plasma: a successful treatment of lesions in Hailey-Hailey disease.
Archives of dermatology.
2011 Apr; 147(4):388-90. doi:
10.1001/archdermatol.2011.57. [PMID: 21482888] - Russell A Johnson, Geoffrey I McFadden, Christopher D Goodman. Characterization of two malaria parasite organelle translation elongation factor G proteins: the likely targets of the anti-malarial fusidic acid.
PloS one.
2011; 6(6):e20633. doi:
10.1371/journal.pone.0020633. [PMID: 21695207] - Jianglin Zhao, Yan Mou, Tijiang Shan, Yan Li, Ligang Zhou, Mingan Wang, Jingguo Wang. Antimicrobial metabolites from the endophytic fungus Pichia guilliermondii isolated from Paris polyphylla var. yunnanensis.
Molecules (Basel, Switzerland).
2010 Nov; 15(11):7961-70. doi:
10.3390/molecules15117961. [PMID: 21060302] - Ciara N Magee, Samar A Medani, Sean F Leavey, Peter J Conlon, Michael R Clarkson. Severe rhabdomyolysis as a consequence of the interaction of fusidic acid and atorvastatin.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2010 Nov; 56(5):e11-5. doi:
10.1053/j.ajkd.2010.07.011. [PMID: 20888103] - Sara Brosche, Thomas Backhaus. Toxicity of five protein synthesis inhibiting antibiotics and their mixture to limnic bacterial communities.
Aquatic toxicology (Amsterdam, Netherlands).
2010 Sep; 99(4):457-65. doi:
10.1016/j.aquatox.2010.06.008. [PMID: 20655118] - S Teckchandani, S Robertson, A Almond, K Donaldson, C Isles. Rhabdomyolysis following co-prescription of fusidic acid and atorvastatin.
The journal of the Royal College of Physicians of Edinburgh.
2010 Mar; 40(1):33-6. doi:
10.4997/jrcpe.2010.108. [PMID: 21125037] - Douglas J Biedenbach, Paul R Rhomberg, Rodrigo E Mendes, Ronald N Jones. Spectrum of activity, mutation rates, synergistic interactions, and the effects of pH and serum proteins for fusidic acid (CEM-102).
Diagnostic microbiology and infectious disease.
2010 Mar; 66(3):301-7. doi:
10.1016/j.diagmicrobio.2009.10.014. [PMID: 20159376] - Helmut Schöfer, Lene Simonsen. Fusidic acid in dermatology: an updated review.
European journal of dermatology : EJD.
2010 Jan; 20(1):6-15. doi:
10.1684/ejd.2010.0833. [PMID: 20007058] - M Gul, A Yasim, M Aral. The levels of cytokines in rats following the use of prophylactic agents in vascular graft infection.
Bratislavske lekarske listy.
2010; 111(6):316-20. doi:
. [PMID: 20635674] - Kanako Saruya, Hidetsugu Fukuda, Ryuzo Saito, Osamu Urushibata, Hideki Mukai. Plasmocytosis circumorificialis successfully treated with topical fusidic acid ointment.
The Journal of dermatology.
2009 Apr; 36(4):232-6. doi:
10.1111/j.1346-8138.2009.00629.x. [PMID: 19348663] - Anne Helle, Johanna Mäkitalo, Jarkko Huhtanen, Juha M Holopainen, Susanne K Wiedmer. Antibiotic fusidic acid has strong interactions with negatively charged lipid membranes: an electrokinetic capillary chromatographic study.
Biochimica et biophysica acta.
2008 Nov; 1778(11):2640-7. doi:
10.1016/j.bbamem.2008.06.019. [PMID: 18680718] - K Kanellakopoulou, D Tselikos, E Giannitsioti, E J Giamarellos-Bourboulis, E Apostolakis, C Lolas, H Giamarellou. Pharmacokinetics of fusidic acid and cefepime in heart tissues: implications for a role in surgical prophylaxis.
Journal of chemotherapy (Florence, Italy).
2008 Aug; 20(4):468-71. doi:
10.1179/joc.2008.20.4.468. [PMID: 18676227] - A J Burtenshaw, G Sellors, R Downing. Presumed interaction of fusidic acid with simvastatin.
Anaesthesia.
2008 Jun; 63(6):656-8. doi:
10.1111/j.1365-2044.2007.05434.x. [PMID: 18477279] - C O'Mahony, V L Campbell, M S Al-Khayatt, D J Brull. Rhabdomyolysis with atorvastatin and fusidic acid.
Postgraduate medical journal.
2008 Jun; 84(992):325-7. doi:
10.1136/pgmj.2007.064097. [PMID: 18644925] - A R Larsen, R L Skov, V Jarlier, A S Henriksen. Epidemiological differences between the UK and Ireland versus France in Staphylococcus aureus isolates resistant to fusidic acid from community-acquired skin and soft tissue infections.
The Journal of antimicrobial chemotherapy.
2008 Mar; 61(3):589-94. doi:
10.1093/jac/dkm532. [PMID: 18222948] - Jaana Muhonen, Jukka Vidgren, Anne Helle, Gebrenegus Yohannes, Tapani Viitala, Juha M Holopainen, Susanne K Wiedmer. Interactions of fusidic acid and elongation factor G with lipid membranes.
Analytical biochemistry.
2008 Mar; 374(1):133-42. doi:
10.1016/j.ab.2007.10.014. [PMID: 17980694] - Ming-Shi Shiao, Jing-Jing Chiu, Bao-Wen Chang, Jane Wang, Wei-Ping Jen, Ye-Jer Wu, Yuh-Lien Chen. In search of antioxidants and anti-atherosclerotic agents from herbal medicines.
BioFactors (Oxford, England).
2008; 34(2):147-57. doi:
10.1002/biof.5520340206. [PMID: 19706980] - L Simonsen, A Fullerton. Development of an in vitro skin permeation model simulating atopic dermatitis skin for the evaluation of dermatological products.
Skin pharmacology and physiology.
2007; 20(5):230-6. doi:
10.1159/000104421. [PMID: 17587887] - Finn Schultz Larsen, Lene Simonsen, Anita Melgaard, Katja Wendicke, Anne S Henriksen. An efficient new formulation of fusidic acid and betamethasone 17-valerate (fucicort lipid cream) for treatment of clinically infected atopic dermatitis.
Acta dermato-venereologica.
2007; 87(1):62-8. doi:
10.2340/00015555-0174. [PMID: 17225018] - T Norén, M Wullt, Thomas Akerlund, E Bäck, I Odenholt, L G Burman. Frequent emergence of resistance in Clostridium difficile during treatment of C. difficile-associated diarrhea with fusidic acid.
Antimicrobial agents and chemotherapy.
2006 Sep; 50(9):3028-32. doi:
10.1128/aac.00019-06. [PMID: 16940098] - Emma Falck, Jari T Hautala, Mikko Karttunen, Paavo K J Kinnunen, Michael Patra, Heikki Saaren-Seppälä, Ilpo Vattulainen, Susanne K Wiedmer, Juha M Holopainen. Interaction of fusidic acid with lipid membranes: Implications to the mechanism of antibiotic activity.
Biophysical journal.
2006 Sep; 91(5):1787-99. doi:
10.1529/biophysj.106.084525. [PMID: 16782792] - Niraikulam Ayyadurai, Sundar Isaac Kirubakaran, Sirobhooshanam Srisha, Natarajan Sakthivel. Biological and molecular variability of Sarocladium oryzae, the sheath rot pathogen of rice (Oryza sativa L.).
Current microbiology.
2005 Jun; 50(6):319-23. doi:
10.1007/s00284-005-4509-6. [PMID: 15968500] - Silke Besier, Albrecht Ludwig, Volker Brade, Thomas A Wichelhaus. Compensatory adaptation to the loss of biological fitness associated with acquisition of fusidic acid resistance in Staphylococcus aureus.
Antimicrobial agents and chemotherapy.
2005 Apr; 49(4):1426-31. doi:
10.1128/aac.49.4.1426-1431.2005. [PMID: 15793122] - J Y Liu, Y C Song, Z Zhang, L Wang, Z J Guo, W X Zou, R X Tan. Aspergillus fumigatus CY018, an endophytic fungus in Cynodon dactylon as a versatile producer of new and bioactive metabolites.
Journal of biotechnology.
2004 Nov; 114(3):279-87. doi:
10.1016/j.jbiotec.2004.07.008. [PMID: 15522437] - A Hedberg, H-G Hårdemark, B Olsson-Liljequist, J Sjölin. Penetration of fusidic acid and rifampicin into cerebrospinal fluid in low-grade inflammatory meningitis caused by Staphylococcus epidermidis.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
2004 Aug; 10(8):765-8. doi:
10.1111/j.1469-0691.2004.00953.x. [PMID: 15301684] - M Fox, G Gray, K Kavanagh, C Lewis, S Doyle. Detection of Aspergillus fumigatus mycotoxins: immunogen synthesis and immunoassay development.
Journal of microbiological methods.
2004 Feb; 56(2):221-30. doi:
10.1016/j.mimet.2003.10.009. [PMID: 14744451] - Robert Skov, Niels Frimodt-Møller, Frank Espersen. Tentative interpretative zone diameters for fusidic acid Neosensitabs on Mueller Hinton agar and three blood containing media.
International journal of antimicrobial agents.
2003 Nov; 22(5):502-7. doi:
10.1016/s0924-8579(03)00123-7. [PMID: 14602369] - Romina A Danguilan, Liezl P Evangelista, Mildred S Abrenica, Stella Marie S Rondilla. Comparative study of mupirocin and sodium fucidate in the prophylaxis of exit-site infections in CAPD patients.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2003 Nov; 23(6):593-5. doi:
10.1177/089686080302300614. [PMID: 14703203] - Christian Østergaard, Runa Vavia Yieng-Kow, Jenny Dahl Knudsen, Niels Frimodt-Møller, Frank Espersen. Evaluation of fusidic acid in therapy of experimental Staphylococcus aureus meningitis.
The Journal of antimicrobial chemotherapy.
2003 May; 51(5):1301-5. doi:
10.1093/jac/dkg231. [PMID: 12697637] - Ida Hageman, Karsten Buschard. Antidiabetogenic effect of fusidic acid in diabetes prone BB rats: a sex-dependent organ accumulation of the drug is seen.
Pharmacology & toxicology.
2002 Sep; 91(3):123-8. doi:
10.1034/j.1600-0773.2002.910306.x. [PMID: 12427112] - K Osman Memikoğlu, Banu Bayar, Ozlem Kurt, Fügen Cokça. [In vitro sensitivity of methicillin-resistant Staphylococcus aureus to fusidic acid and trimethoprim-sulfamethoxazole].
Mikrobiyoloji bulteni.
2002 Apr; 36(2):141-5. doi:
. [PMID: 12652865] - M Biswas, K Owen, M K Jones. Hypocalcaemia during fusidic acid therapy.
Journal of the Royal Society of Medicine.
2002 Feb; 95(2):91-3. doi:
10.1258/jrsm.95.2.91. [PMID: 11823554] - Peter Kotanko, Waltraud Kirisits, Falko Skrabal. Rhabdomyolysis and acute renal graft impairment in a patient treated with simvastatin, tacrolimus, and fusidic acid.
Nephron.
2002 Feb; 90(2):234-5. doi:
10.1159/000049053. [PMID: 11818715] - M K Ghosh, R Amudha, S Jayachandran, N Sakthivel. Detection and quantification of phytotoxic metabolites of Sarocladium oryzae in sheath rot-infected grains of rice.
Letters in applied microbiology.
2002; 34(6):398-401. doi:
10.1046/j.1472-765x.2002.01111.x. [PMID: 12028418] - R Skov, N Frimodt-Møller, F Espersen. Correlation of MIC methods and tentative interpretive criteria for disk diffusion susceptibility testing using NCCLS methodology for fusidic acid.
Diagnostic microbiology and infectious disease.
2001 Jul; 40(3):111-6. doi:
10.1016/s0732-8893(01)00262-0. [PMID: 11502378] - A J O'Neill, J H Cove, I Chopra. Mutation frequencies for resistance to fusidic acid and rifampicin in Staphylococcus aureus.
The Journal of antimicrobial chemotherapy.
2001 May; 47(5):647-50. doi:
10.1093/jac/47.5.647. [PMID: 11328777] - O Propheta, J Vierula, P Toporowski, R Gorovits, O Yarden. The Neurospora crassa colonial temperature-sensitive 3 (cot-3) gene encodes protein elongation factor 2.
Molecular & general genetics : MGG.
2001 Feb; 264(6):894-901. doi:
10.1007/s004380000379. [PMID: 11254137] - L Vaillant, C Le Guellec, F Jehl, R Barruet, H Sorensen, R Roiron, E Autret-Leca, G Lorette. [Comparative diffusion of fusidic acid, oxacillin, and pristinamycin in dermal interstitial fluid after repeated oral administration].
Annales de dermatologie et de venereologie.
2000 Jan; 127(1):33-9. doi:
. [PMID: 10717560] - G Reimann, B Barthel, J K Rockstroh, D Spatz, N H Brockmeyer. Effect of fusidic acid on the hepatic cytochrome P450 enzyme system.
International journal of clinical pharmacology and therapeutics.
1999 Nov; 37(11):562-6. doi:
. [PMID: 10584978] - P Collignon, J Turnidge. Fusidic acid in vitro activity.
International journal of antimicrobial agents.
1999 Aug; 12 Suppl 2(?):S45-58. doi:
10.1016/s0924-8579(98)00073-9. [PMID: 10528786] - K Christiansen. Fusidic acid adverse drug reactions.
International journal of antimicrobial agents.
1999 Aug; 12 Suppl 2(?):S3-9. doi:
10.1016/s0924-8579(98)00068-5. [PMID: 10528781] - E Somekh, T Golan, A Tanay, F Poch, M Dan. Concentration and bactericidal activity of fusidic acid and cloxacillin in serum and synovial fluid.
The Journal of antimicrobial chemotherapy.
1999 Apr; 43(4):593-6. doi:
10.1093/jac/43.4.593. [PMID: 10350394] - S L Nielsen, F T Black. Extracellular and intracellular killing in neutrophil granulocytes of Staphylococcus aureus with rifampicin in combination with dicloxacillin or fusidic acid.
The Journal of antimicrobial chemotherapy.
1999 Mar; 43(3):407-10. doi:
10.1093/jac/43.3.407. [PMID: 10223598] - M O Osman, T El-Sefi, S B Lausten, N O Jacobsen, C G Larsen, S L Jensen. Sodium fusidate and the cytokine response in an experimental model of acute pancreatitis.
The British journal of surgery.
1998 Nov; 85(11):1487-92. doi:
10.1046/j.1365-2168.1998.00867.x. [PMID: 9823907] - S L Nielsen, F T Black. The effect of dicloxacillin and fusidic acid on the extracellular and intracellular killing of Staphylococcus aureus.
The Journal of antimicrobial chemotherapy.
1998 Aug; 42(2):221-6. doi:
10.1093/jac/42.2.221. [PMID: 9738840] - C Fallgren, M Utt, A C Petersson, A Ljungh, T Wadström. In vitro anti-staphylococcal activity of heparinized biomaterials bonded with combinations of rifampicin.
Zentralblatt fur Bakteriologie : international journal of medical microbiology.
1998 Jan; 287(1-2):19-31. doi:
10.1016/s0934-8840(98)80137-0. [PMID: 9532261] - F Nicoletti, B Beltrami, E Raschi, R Di Marco, G Magro, S Grasso, K Bendtzen, G Fiorelli, P L Meroni. Protection from concanavalin A (Con A)-induced T cell-dependent hepatic lesions and modulation of cytokine release in mice by sodium fusidate.
Clinical and experimental immunology.
1997 Dec; 110(3):479-84. doi:
10.1046/j.1365-2249.1997.4091423.x. [PMID: 9409654] - S Hulin, Y Durandy. [Postoperative mediastinitis due to methicillin resistant Staphylococcus epidermidis with low sensitivity to vancomycin].
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie.
1997 Dec; 4(12):1204-6. doi:
10.1016/s0929-693x(97)82610-3. [PMID: 9538424] - A Ferroni, J Merckx, T Ancelle, B Pron, E Abachin, F Barbut, J Larzul, P Rigault, P Berche, J L Gaillard. Nosocomial outbreak of Clostridium difficile diarrhea in a pediatric service.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
1997 Dec; 16(12):928-33. doi:
10.1007/bf01700562. [PMID: 9495676] - S Sommer, R Bojar, W J Cunliffe, D Holland, K T Holland, H Naags. Investigation of the mechanism of action of 2\% fusidic acid lotion in the treatment of acne vulgaris.
Clinical and experimental dermatology.
1997 Sep; 22(5):211-5. doi:
". [PMID: 9536540] - N M Brown, D S Reeves, C M McMullin. The pharmacokinetics and protein-binding of fusidic acid in patients with severe renal failure requiring either haemodialysis or continuous ambulatory peritoneal dialysis.
The Journal of antimicrobial chemotherapy.
1997 Jun; 39(6):803-9. doi:
10.1093/jac/39.6.803. [PMID: 9222051] - J P Davies, P A Alderman. Acute renal failure in association with fusidic acid.
International journal of clinical practice.
1997 Jun; 51(4):264. doi:
NULL. [PMID: 9287276] - E Marttin, J C Verhoef, C Cullander, S G Romeijn, J F Nagelkerke, F W Merkus. Confocal laser scanning microscopic visualization of the transport of dextrans after nasal administration to rats: effects of absorption enhancers.
Pharmaceutical research.
1997 May; 14(5):631-7. doi:
10.1023/a:1012109329631. [PMID: 9165535] - B Georges, L Brown, M Mazerolles, J F Decun, P Cougot, M Archambaud, C Suc, P Andrieu, C Virenque. [Severe methicillin-resistant Staphylococcus aureus infections. Emergence of resistance to fusidic acid or fosfomycin during treatment with continuous infusion of vancomycin].
Presse medicale (Paris, France : 1983).
1997 Apr; 26(11):502-6. doi:
. [PMID: 9137379] - F Genovese, G Mancuso, M Cuzzola, V Cusumano, F Nicoletti, K Bendtzen, G Teti. Improved survival and antagonistic effect of sodium fusidate on tumor necrosis factor alpha in a neonatal mouse model of endotoxin shock.
Antimicrobial agents and chemotherapy.
1996 Jul; 40(7):1733-5. doi:
10.1128/aac.40.7.1733. [PMID: 8807074] - N El-Kassar, P Kalfon, P Fromont, C Vezinet, B Godeau, N Duedari, P Bierling. Fusidic acid induced acute immunologic thrombocytopenia.
British journal of haematology.
1996 May; 93(2):427-31. doi:
10.1046/j.1365-2141.1996.5211064.x. [PMID: 8639443] - C Alegre, R Iglesias, J M Ferreras, L Citores, T Girbés. Sensitivity of ribosomes from Agrobacterium tumefaciens to the ribosome-inactivating protein crotin 2 depending on the translocational state.
Cellular and molecular biology (Noisy-le-Grand, France).
1996 Mar; 42(2):151-8. doi:
". [PMID: 8696251] - V Mahler, O P Hornstein, F Kiesewetter. Plasma cell gingivitis: treatment with 2\% fusidic acid.
Journal of the American Academy of Dermatology.
1996 Jan; 34(1):145-6. doi:
10.1016/s0190-9622(96)90865-8. [PMID: 8543685]