Procaine hydrochloride (BioDeep_00000015151)
代谢物信息卡片
Procaine hydrochloride
化学式: C13H21ClN2O2 (272.1291476)
中文名称: 盐酸普鲁卡因
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.Cl
InChI: 1H
描述信息
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
C78272 - Agent Affecting Nervous System > C245 - Anesthetic Agent
同义名列表
1 个代谢物同义名
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:8431
- KEGG: C07894
- KEGGdrug: D78370
- KEGGdrug: D00740
- PubChem: 5795
- ChEMBL: CHEMBL1200841
- MeSH: Procaine
- CAS: 51-05-8
- PubChem: 10096
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Miaomiao Song, Yaping Chen. Local anaesthetic procaine derivatives protect rat against diabetic nephropathy via inhibition of DPP-4, inflammation and oxidative stress.
Chemical biology & drug design.
2023 Apr; ?(?):. doi:
10.1111/cbdd.14252. [PMID: 37076428] - David Vinyes, Montserrat Muñoz-Sellart, Teresa García Caballero. Local anesthetics as a therapeutic tool for post COVID-19 patients: A case report.
Medicine.
2022 Jul; 101(28):e29358. doi:
10.1097/md.0000000000029358. [PMID: 35839020] - Juan P Ortiz Fragola, Gabriel Cao, Mariano Tumarkin, Marisa Moriondo, Angélica Muller, Martin Sangiorgio, Francisco Azzato, Giuseppe Ambrosio, José Milei. Bretschneider Solution and Two Antianginal Drugs Protect Peripheral Tissue in an Animal Model of Hemorrhagic Shock.
Journal of cardiovascular pharmacology.
2022 Jun; 79(6):896-903. doi:
10.1097/fjc.0000000000001253. [PMID: 35249963] - Elsbeth J Wesselink, Seppe J Koopman, Rien van der Vegt, Peter M van de Ven, Jan P van der Aa, Carlijne Stapper, Friso Wesdorp, Laura de Kok, Yiyi Zhang, Eric J Franssen, Eleonora L Swart, Christa Boer, Marcel A de Leeuw. ED90 of spinal 2-chloroprocaine 1\% in ambulatory knee arthroscopy up to 45 min: a randomized biased-coin- up-and-down sequential allocation trial.
Regional anesthesia and pain medicine.
2022 04; 47(4):212-216. doi:
10.1136/rapm-2021-103089. [PMID: 35027477] - Allison Lee, Ben Shatil, Ruth Landau, Prahlad Menon, Richard Smiley. Intrathecal 2-Chloroprocaine 3\% Versus Hyperbaric Bupivacaine 0.75\% for Cervical Cerclage: A Double-Blind Randomized Controlled Trial.
Anesthesia and analgesia.
2022 03; 134(3):624-632. doi:
10.1213/ane.0000000000005653. [PMID: 34153006] - Augustinas Bausys, Juste Maneikyte, Bettina Leber, Jennifer Weber, Nicole Feldbacher, Kestutis Strupas, Thomas Bernd Dschietzig, Peter Schemmer, Philipp Stiegler. Custodiol® Supplemented with Synthetic Human Relaxin Decreases Ischemia-Reperfusion Injury after Porcine Kidney Transplantation.
International journal of molecular sciences.
2021 Oct; 22(21):. doi:
10.3390/ijms222111417. [PMID: 34768845] - Charlotte von Horn, Benjamin Wilde, Ursula Rauen, Andreas Paul, Thomas Minor. Use of the new preservation solution Custodiol-MP for ex vivo reconditioning of kidney grafts.
Artificial organs.
2021 Sep; 45(9):1117-1123. doi:
10.1111/aor.13951. [PMID: 33683761] - Immanuel I Turner, Mark Ruzmetov, Jianli Niu, Steven Bibevski, Frank G Scholl. Scavenging right atrial Bretschneider histidine-tryptophan-ketoglutarate cardioplegia: Impact on hyponatremia and seizures in pediatric cardiac surgery patients.
The Journal of thoracic and cardiovascular surgery.
2021 Jul; 162(1):228-237. doi:
10.1016/j.jtcvs.2020.08.098. [PMID: 33036746] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Yi-Bo Yan, Shuo Shi, Qian-Biao Wu, Jin-Sheng Cai, Bin-Feng Lei. Effect of different cardioprotective methods on extracorporeal circulation in fetal sheep: a randomized controlled trial.
Journal of cardiothoracic surgery.
2021 Apr; 16(1):94. doi:
10.1186/s13019-021-01486-y. [PMID: 33865409] - Daniela Ghisi, Giorgia Boschetto, Alessandra Maria Spinelli, Sandra Giannone, Jacopo Frugiuele, Marcello Ciccarello, Stefano Bonarelli. Spinal anaesthesia with Chloroprocaine HCl 1\% for elective lower limb procedures of short duration: a prospective, randomised, observer-blind study in adult patients.
BMC anesthesiology.
2021 02; 21(1):58. doi:
10.1186/s12871-021-01279-9. [PMID: 33610175] - Zoltan Czigany, Eve Christiana Craigie, Georg Lurje, Shaowei Song, Kei Yonezawa, Yuzo Yamamoto, Thomas Minor, René Hany Tolba. Adenosine A2a Receptor Stimulation Attenuates Ischemia-Reperfusion Injury and Improves Survival in A Porcine Model of DCD Liver Transplantation.
International journal of molecular sciences.
2020 Sep; 21(18):. doi:
10.3390/ijms21186747. [PMID: 32938013] - Annika Mohr, Jens G Brockmann, Felix Becker. HTK-N: Modified Histidine-Tryptophan-Ketoglutarate Solution-A Promising New Tool in Solid Organ Preservation.
International journal of molecular sciences.
2020 Sep; 21(18):. doi:
10.3390/ijms21186468. [PMID: 32899772] - Aneta Ostróżka-Cieślik, Barbara Dolińska, Florian Ryszka. The Effectiveness of Rinsing Organs With Selected Preservation Solutions Based on the Analysis of Their Physicochemical Parameters.
Transplantation proceedings.
2020 Sep; 52(7):2050-2054. doi:
10.1016/j.transproceed.2020.01.101. [PMID: 32278582] - Jiani Huang, Fang Wen, Wenjie Huang, Yingfeng Bai, Xiaona Lu, Peng Shu. Identification of hub genes and discovery of promising compounds in gastric cancer based on bioinformatics analysis.
Biomarkers in medicine.
2020 08; 14(12):1069-1084. doi:
10.2217/bmm-2019-0608. [PMID: 32969243] - Aldo Elias Kiyoshi Takano de Saidneuy, Marcelo Bruno de Rezende, Paolo Rogerio de Oliveira Salvalaggio. A Direct Comparison Between Institut Georges Lopez 1 and Histidine-Tryptophan-Ketoglutarate Preservation Solutions in Liver Transplantation.
Transplantation proceedings.
2020 Jun; 52(5):1262-1264. doi:
10.1016/j.transproceed.2020.01.172. [PMID: 32507487] - Giovanni Tinelli, Simona Sica, Fabrizio Minelli, Marco Natola, Francesca De Nigris, Yamume Tshomba. Horseshoe Kidney Protection with Histidine-Tryptophan-Ketoglutarate Solution during Surgical Abdominal Aortic Aneurysm Repair.
Annals of vascular surgery.
2020 Feb; 63(?):459.e5-459.e8. doi:
10.1016/j.avsg.2019.08.105. [PMID: 31622767] - Daniela Kniepeiss, Philipp Houben, Philipp Stiegler, Andrea Berghold, Regina Riedl, Judith Kahn, Peter Schemmer. A prospective, randomized, single-blind, multicentre, phase III study on organ preservation with Custodiol-N solution compared with Custodiol® solution in organ transplantation (kidney, liver and pancreas).
Trials.
2020 Jan; 21(1):62. doi:
10.1186/s13063-019-3823-4. [PMID: 31924234] - Anca Ungurianu, Denisa Margina, Claudia Borsa, Cristina Ionescu, Gudrun von Scheven, Lucie Oziol, Philippe Faure, Yves Artur, Alexander Bürkle, Daniela Gradinaru, Maria Moreno-Villanueva. The Radioprotective Effect of Procaine and Procaine-Derived Product Gerovital H3 in Lymphocytes from Young and Aged Individuals.
Oxidative medicine and cellular longevity.
2020; 2020(?):3580934. doi:
10.1155/2020/3580934. [PMID: 32685092] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Gregor Fabry, Benedict M Doorschodt, Tim Grzanna, Peter Boor, Aaron Elliott, André Stollenwerk, René H Tolba, Rolf Rossaint, Christian Bleilevens. Cold Preflush of Porcine Kidney Grafts Prior to Normothermic Machine Perfusion Aggravates Ischemia Reperfusion Injury.
Scientific reports.
2019 09; 9(1):13897. doi:
10.1038/s41598-019-50101-7. [PMID: 31554887] - Pia Weiler, Marwan Hamiko, Fritz Mellert, Wilhelm Roell, Martina Roell, Cecilia Welz, Georg Daniel Duerr. Impact of Crystalloid or Albumin Priming of the Heart-Lung Machine on Inhospital Outcome after Coronary Artery Bypass Surgery.
The Thoracic and cardiovascular surgeon.
2019 Sep; 67(6):475-483. doi:
10.1055/s-0038-1667328. [PMID: 30049018] - Jan Weis, Håkan Ahlström, Olle Korsgren. Proton MR spectroscopy of human pancreas allografts.
Magma (New York, N.Y.).
2019 Aug; 32(4):511-517. doi:
10.1007/s10334-019-00740-8. [PMID: 30937576] - Mehmet Haberal, Mahir Kirnap, S Remzi Erdem, B Handan Ozdemir, K Michael Lux, Didem Bacanli. Evaluation of New Baskent University Preservation Solution for Kidney Graft During Cold Ischemia: Preliminary Experimental Animal Study.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.
2019 06; 17(3):287-297. doi:
10.6002/ect.bups2019. [PMID: 31145052] - Katharina Hofmann, Anna Rauh, Jürgen Harlizius, Christine Weiß, Tobias Scholz, Theodor Schulze-Horsel, Damián Escribano, Mathias Ritzmann, Susanne Zöls. [Pain and distress responses of suckling piglets to injection and castration under local anaesthesia with procaine and lidocaine - Part 1: Cortisol, chromogranin A, wound healing, weights, losses].
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere.
2019 Apr; 47(2):87-96. doi:
10.1055/a-0861-9640. [PMID: 30999349] - Camila Arroyo-Salvo, Francisco Sanhueza, Fernanda Fuentes, Favián Treulén, María Elena Arias, Paulina Cabrera, Mauricio Silva, Ricardo Felmer. Effect of human tubal fluid medium and hyperactivation inducers on stallion sperm capacitation and hyperactivation.
Reproduction in domestic animals = Zuchthygiene.
2019 Feb; 54(2):184-194. doi:
10.1111/rda.13328. [PMID: 30179285] - Cheng-Chia Lee, Ya-Ju Hsieh, Shao-Wei Chen, Shu-Hsuan Fu, Chia-Wei Hsu, Chih-Ching Wu, Wei Han, Yunong Li, Tao Huan, Yu-Sun Chang, Jau-Song Yu, Liang Li, Chih-Hsiang Chang, Yi-Ting Chen. Bretschneider solution-induced alterations in the urine metabolome in cardiac surgery patients.
Scientific reports.
2018 12; 8(1):17774. doi:
10.1038/s41598-018-35631-w. [PMID: 30538262] - Soma Sengupta, Paramita Paul, Biswajit Mukherjee, Raghuvir H Gaonkar, Mita Chatterjee Debnath, Rhitabrita Chakraborty, Nobila Khatun, Somdatta Roy. Peripheral nerve targeting by procaine-conjugated ribavirin-loaded dual drug nanovesicle.
Nanomedicine (London, England).
2018 12; 13(23):3009-3023. doi:
10.2217/nnm-2018-0192. [PMID: 30507340] - B Szulc-Musioł, B Dolińska, K Jasik, F Ryszka. Effect of Prolactin on Biochemical and Morphological Parameters of Rabbit Liver in Warm Ischemia.
Transplantation proceedings.
2018 Sep; 50(7):2229-2234. doi:
10.1016/j.transproceed.2018.02.135. [PMID: 30177141] - A Ostróżka-Cieślik, B Dolińska, K Czyż. Analysis of Interactions Between Components of Selected Solution for Organ Perfusion and Preservation.
Transplantation proceedings.
2018 Sep; 50(7):1967-1970. doi:
10.1016/j.transproceed.2018.02.166. [PMID: 30177089] - Junhong Lin. Platelet-rich plasma injection in the treatment of frozen shoulder: A randomized controlled trial with 6-month follow-up
.
International journal of clinical pharmacology and therapeutics.
2018 Aug; 56(8):366-371. doi:
10.5414/cp203262. [PMID: 29932415] - Fan Wu, Jintao Wang, Jianming Sun, Liman Shen, Meijuan Liu, Erjun Zhao. Procaine stimulates aquaporin‑5 expression in human salivary gland ductal cells via the suppression of DNA methyltransferase‑1.
Molecular medicine reports.
2018 Jun; 17(6):7996-8002. doi:
10.3892/mmr.2018.8821. [PMID: 29620185] - J K Teloh, L Ansorge, M Petersen, E Demircioglu, I N Waack, S Brauckmann, H Jakob, D-S Dohle. Histidine metabolism after Bretschneider cardioplegia in cardiac surgical patients.
Physiological research.
2018 05; 67(2):209-216. doi:
10.33549/physiolres.933691. [PMID: 29303608] - Jindong Li, Yanhong Wu, Xudong Tian, Jiantang Wang, Mingfeng Dong, Anbiao Wang, Shengjun Ma. Protective effect of HTK solution on postoperative pulmonary function in infants with CHD and PAH.
Bioscience reports.
2017 Dec; 37(6):. doi:
10.1042/bsr20170984. [PMID: 29089468] - W-Y Fan, D-P Wang, Q Wen, T-J Fan. The cytotoxic effect of oxybuprocaine on human corneal epithelial cells by inducing cell cycle arrest and mitochondria-dependent apoptosis.
Human & experimental toxicology.
2017 Aug; 36(8):765-775. doi:
10.1177/0960327116665676. [PMID: 27590991] - Giorgio Veneziano, Joseph D Tobias. Chloroprocaine for epidural anesthesia in infants and children.
Paediatric anaesthesia.
2017 Jun; 27(6):581-590. doi:
10.1111/pan.13134. [PMID: 28321983] - Seifollah Jalili, Marzieh Saeedi. Study of procaine and tetracaine in the lipid bilayer using molecular dynamics simulation.
European biophysics journal : EBJ.
2017 Apr; 46(3):265-282. doi:
10.1007/s00249-016-1164-8. [PMID: 27557558] - Mohammad Golriz, Hamidreza Fonouni, Gani Kuttymuratov, Majid Esmaeilzadeh, Morva Tahmasbi Rad, Parvin Jarahian, Thomas Longerich, Alireza Faridar, Sepehr Abbasi, Arianeb Mehrabi, Marta M Gebhard. Influence of a modified preservation solution in kidney transplantation: A comparative experimental study in a porcine model.
Asian journal of surgery.
2017 Apr; 40(2):106-115. doi:
10.1016/j.asjsur.2015.07.001. [PMID: 26337376] - Micaela De Palo, Pietro Guida, Florinda Mastro, Daniela Nanna, Teresa A P Quagliara, Ruggiero Rociola, Giosuè Lionetti, Domenico Paparella. Myocardial protection during minimally invasive cardiac surgery through right mini-thoracotomy.
Perfusion.
2017 Apr; 32(3):245-252. doi:
10.1177/0267659116679249. [PMID: 28327076] - J Moritz Kaths, Juan Echeverri, Yi Min Chun, Jun Yu Cen, Nicolas Goldaracena, Ivan Linares, Luke S Dingwell, Paul M Yip, Rohan John, Darius Bagli, Istvan Mucsi, Anand Ghanekar, David R Grant, Lisa A Robinson, Markus Selzner. Continuous Normothermic Ex Vivo Kidney Perfusion Improves Graft Function in Donation After Circulatory Death Pig Kidney Transplantation.
Transplantation.
2017 Apr; 101(4):754-763. doi:
10.1097/tp.0000000000001343. [PMID: 27467537] - Xu-Jiao Yu, Wei Zhao, Yu-Jie Li, Feng-Xian Li, Zhong-Jie Liu, Hua-Li Xu, Lu-Ying Lai, Rui Xu, Shi-Yuan Xu. Neurotoxicity Comparison of Two Types of Local Anaesthetics: Amide-Bupivacaine versus Ester-Procaine.
Scientific reports.
2017 03; 7(?):45316. doi:
10.1038/srep45316. [PMID: 28338089] - Dan Liu, Jingdong Peng, Shaopu Liu, Mingqiong Zhou, Jing Zhang, Aiping Li. Resonance Rayleigh scattering technique as a detection method for the RP-HPLC determination of local anaesthetics in human urine.
Luminescence : the journal of biological and chemical luminescence.
2017 Feb; 32(1):4-10. doi:
10.1002/bio.3140. [PMID: 27145989] - J Moritz Kaths, Juan Echeverri, Nicolas Goldaracena, Kristine S Louis, Yi-Min Chun, Ivan Linares, Aryn Wiebe, Daniel B Foltys, Paul M Yip, Rohan John, Istvan Mucsi, Anand Ghanekar, Darius J Bagli, David R Grant, Lisa A Robinson, Markus Selzner. Eight-Hour Continuous Normothermic Ex Vivo Kidney Perfusion Is a Safe Preservation Technique for Kidney Transplantation: A New Opportunity for the Storage, Assessment, and Repair of Kidney Grafts.
Transplantation.
2016 Sep; 100(9):1862-70. doi:
10.1097/tp.0000000000001299. [PMID: 27479157] - Johanna K Teloh, Daniel-Sebastian Dohle, Miriam Petersen, Rabea Verhaegh, Indra N Waack, Friederike Roehrborn, Heinz Jakob, Herbert de Groot. Histidine and other amino acids in blood and urine after administration of Bretschneider solution (HTK) for cardioplegic arrest in patients: effects on N-metabolism.
Amino acids.
2016 06; 48(6):1423-32. doi:
10.1007/s00726-016-2195-2. [PMID: 26922473] - Majid Esmaeilzadeh, Hamidreza Fonouni, Mohammad Golriz, Ali Majlesara, Gani Kuttymuratov, Frank Bergmann, Parvin Jarahian, Zahra Khazaeipour, Alireza Faridar, Morva Tahmasbi Rad, Thomas Longerich, Martha M Gebhard, Arianeb Mehrabi. Evaluation of the modified HTK solution in pancreas transplantation-An experimental model.
Asian journal of surgery.
2016 Apr; 39(2):66-73. doi:
10.1016/j.asjsur.2015.03.017. [PMID: 26216260] - Giorgio Veneziano, Peter Iliev, Jennifer Tripi, David Martin, Jennifer Aldrink, Tarun Bhalla, Joseph Tobias. Continuous chloroprocaine infusion for thoracic and caudal epidurals as a postoperative analgesia modality in neonates, infants, and children.
Paediatric anaesthesia.
2016 Jan; 26(1):84-91. doi:
10.1111/pan.12807. [PMID: 26530835] - S Su, J Wu, T Gong, K He, C Feng, M Zhang, B Li, X Xia. Inhibition of High Mobility Group Box 1-Toll-Like Receptor-4 Signaling by Glycyrrhizin Contributes to the Attenuation of Cold Ischemic Injury of Liver in a Rat Model.
Transplantation proceedings.
2016 Jan; 48(1):191-8. doi:
10.1016/j.transproceed.2015.12.014. [PMID: 26915867] - Julia Kalenski, Elina Mancina, Pascal Paschenda, Christian Beckers, Christian Bleilevens, Ľubomíra Tóthová, Peter Boor, Dominik Gross, René H Tolba, Benedict M Doorschodt. Comparison of Aerobic Preservation by Venous Systemic Oxygen Persufflation or Oxygenated Machine Perfusion of Warm-Ischemia-Damaged Porcine Kidneys.
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes.
2016; 57(1-2):10-21. doi:
10.1159/000444851. [PMID: 27070724] - María del Mar LópezGuerrero, Maykel Hernández-Mesa, Carmen Cruces-Blanco, Ana M García-Campaña. On-line preconcentration strategy for the simultaneous quantification of three local anesthetics in human urine using CZE.
Electrophoresis.
2015 Dec; 36(23):2961-7. doi:
10.1002/elps.201500081. [PMID: 26436521] - Denis Sadovsky, Oleg Kalachik, Elena Oganova, Dzmitry Fedoruk, Eugeny Kruchenok, Oleg Rummo. Preservation Solution Effluent Osmolality as a Predictor of Initial Kidney Transplant Dysfunction.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.
2015 Nov; 13 Suppl 3(?):84-7. doi:
10.6002/ect.tdtd2015.p47. [PMID: 26640921] - Wolf Ramackers, Johannes Klose, Andreas Tiede, Sonja Werwitzke, Dennis Rataj, Lars Friedrich, Kai Johanning, Florian W R Vondran, Sabine Bergmann, Wolfgang Schuettler, Clemens Luitpold Bockmeyer, Jan Ulrich Becker, Jürgen Klempnauer, Michael Winkler. Effect of TNF-alpha blockade on coagulopathy and endothelial cell activation in xenoperfused porcine kidneys.
Xenotransplantation.
2015 Jul; 22(4):284-94. doi:
10.1111/xen.12179. [PMID: 26216261] - M H Meine, I Leipnitz, M L Zanotelli, E S Schlindwein, G Kiss, J Martini, A de Medeiros Fleck, M Mucenic, A de Mello Brandão, C A Marroni, G P Craco Cantisani. Comparison Between IGL-1 and HTK Preservation Solutions in Deceased Donor Liver Transplantation.
Transplantation proceedings.
2015 May; 47(4):888-93. doi:
10.1016/j.transproceed.2015.03.033. [PMID: 26036479] - Julia Kalenski, Elina Mancina, Pascal Paschenda, Christian Beckers, Christian Bleilevens, Ľubomíra Tóthová, Peter Boor, Benedict Maria Doorschodt, René Hany Tolba. Improved preservation of warm ischemia-damaged porcine kidneys after cold storage in Ecosol, a novel preservation solution.
Annals of transplantation.
2015 Apr; 20(?):233-42. doi:
10.12659/aot.892823. [PMID: 25912926] - Karola Trescher, Elda Dzilic, Maximilian Kreibich, Harald Gasser, Klaus Aumayr, Dontscho Kerjaschki, Brigitte Pelzmann, Seth Hallström, Bruno K Podesser. The nitric oxide donor, S-nitroso human serum albumin, as an adjunct to HTK-N cardioplegia improves protection during cardioplegic arrest after myocardial infarction in rats.
Interactive cardiovascular and thoracic surgery.
2015 Mar; 20(3):387-94. doi:
10.1093/icvts/ivu383. [PMID: 25468794] - Philipp Lirk, Susanne Picardi, Markus W Hollmann. Local anaesthetics: 10 essentials.
European journal of anaesthesiology.
2014 Nov; 31(11):575-85. doi:
10.1097/eja.0000000000000137. [PMID: 25192265] - Patricio A Zapata-Morin, F J Sierra-Valdez, J C Ruiz-Suárez. The interaction of local anesthetics with lipid membranes.
Journal of molecular graphics & modelling.
2014 Sep; 53(?):200-205. doi:
10.1016/j.jmgm.2014.08.001. [PMID: 25181454] - ". [Prevention of peritoneal desiccation in acute adhesive intestinal obstruction].
Georgian medical news.
2014 Jul; ?(232-233):103-7. doi:
". [PMID: 25214283] - Ronald F Parsons, James V Guarrera. Preservation solutions for static cold storage of abdominal allografts: which is best?.
Current opinion in organ transplantation.
2014 Apr; 19(2):100-7. doi:
10.1097/mot.0000000000000063. [PMID: 24553501] - Yamume Tshomba, Andrea Kahlberg, Germano Melissano, Giovanni Coppi, Enrico Marone, Denise Ferrari, Rosalba Lembo, Roberto Chiesa. Comparison of renal perfusion solutions during thoracoabdominal aortic aneurysm repair.
Journal of vascular surgery.
2014 Mar; 59(3):623-33. doi:
10.1016/j.jvs.2013.09.055. [PMID: 24377947] - Marcia R Voigt, Ginger T DeLario. Perspectives on abdominal organ preservation solutions: a comparative literature review.
Progress in transplantation (Aliso Viejo, Calif.).
2013 Dec; 23(4):383-91. doi:
10.7182/pit2013100. [PMID: 24311404] - Yan-Ming Liu, Jie Li, Yang Yang, Jun-Jun Du. Separation and determination of anesthetics by capillary electrophoresis with mixed micelles of sodium dodecyl sulfate and Tween 20 using electrochemiluminescence detection.
Luminescence : the journal of biological and chemical luminescence.
2013 Sep; 28(5):673-8. doi:
10.1002/bio.2414. [PMID: 22961928] - Chao Ma, Ding-Rong Shen, Qing Zhang, Xiang-Chun Meng, Yuan-Xiang Wang, Le Peng, Bao-Ying Meng. [Protective effect of cold autologous blood cardioplegic solution on the heart of infants with cyanotic congenital heart disease].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics.
2013 Jun; 15(6):453-7. doi:
NULL. [PMID: 23791061] - A Caban, B Dolińska, G Budziński, G Oczkowicz, A Ostróżka-Cieślik, L Cierpka, F Ryszka. The effect of HTK solution modification by addition of thyrotropin and corticotropin on biochemical indices reflecting ischemic damage to porcine kidney.
Transplantation proceedings.
2013 Jun; 45(5):1720-2. doi:
10.1016/j.transproceed.2013.01.094. [PMID: 23769031] - Bote G Bruinsma, Ivo C J H Post, Lennart B van Rijssen, Leonie de Boer, Michal Heger, Sebastian A J Zaat, Thomas M van Gulik. Antibiotic prophylaxis in (sub)normothermic organ preservation: in vitro efficacy and toxicity of cephalosporins.
Transplantation.
2013 Apr; 95(8):1064-9. doi:
10.1097/tp.0b013e318284c17a. [PMID: 23411744] - E A Turova, T V Konchugova, E I Balaban, N I Fadeeva, A V Golovach, E A Teniaeva. [The influence of procaine electrophoresis and mesotherapy on the indices of body components and biochemical characteristics in the subjects above 30 years of age].
Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury.
2013 Mar; ?(2):20-3. doi:
". [PMID: 23718080] - Marc Yeste, Eva Flores, Efrén Estrada, Sergi Bonet, Teresa Rigau, Joan E Rodríguez-Gil. Reduced glutathione and procaine hydrochloride protect the nucleoprotein structure of boar spermatozoa during freeze-thawing by stabilising disulfide bonds.
Reproduction, fertility, and development.
2013; 25(7):1036-50. doi:
10.1071/rd12230. [PMID: 23089308] - Sana Asif, Amir Sedigh, Johan Nordström, Heide Brandhorst, Carl Jorns, Tomas Lorant, Erik Larsson, Peetra U Magnusson, Greg Nowak, Sonja Theisinger, Simone Hoeger, Lars Wennberg, Olle Korsgren, Daniel Brandhorst. Oxygen-charged HTK-F6H8 emulsion reduces ischemia-reperfusion injury in kidneys from brain-dead pigs.
The Journal of surgical research.
2012 Dec; 178(2):959-67. doi:
10.1016/j.jss.2012.06.031. [PMID: 22795349] - Nicole Weizenmann, Daniel Huster, Holger A Scheidt. Interaction of local anesthetics with lipid bilayers investigated by ¹H MAS NMR spectroscopy.
Biochimica et biophysica acta.
2012 Dec; 1818(12):3010-8. doi:
10.1016/j.bbamem.2012.07.014. [PMID: 22842001] - Elena Grossini, Claudio Molinari, Piero Pollesello, Giorgio Bellomo, Guido Valente, David Mary, Giovanni Vacca, Philippe Caimmi. Levosimendan protection against kidney ischemia/reperfusion injuries in anesthetized pigs.
The Journal of pharmacology and experimental therapeutics.
2012 Aug; 342(2):376-88. doi:
10.1124/jpet.112.193961. [PMID: 22566668] - Angela Hefti, Inka Schlemmer, Carola Sauter-Louis, Moritz Metzner. [Comparison of three different anesthesia procedures in calves with respect to possible pain-associated reactions].
Berliner und Munchener tierarztliche Wochenschrift.
2012 Jul; 125(7-8):315-25. doi:
NULL. [PMID: 22919925] - Gregor Lindner, Bernhard Zapletal, Christoph Schwarz, Wilfried Wisser, Michael Hiesmayr, Andrea Lassnigg. Acute hyponatremia after cardioplegia by histidine-tryptophane-ketoglutarate--a retrospective study.
Journal of cardiothoracic surgery.
2012 Jun; 7(?):52. doi:
10.1186/1749-8090-7-52. [PMID: 22681759] - J-H Lee, J-H Park, H-J Park, T General, M-G Cho, S-K Lee. Cryopreservation of immobilized rat hepatocytes for the development of a bioartificial liver system.
Transplantation proceedings.
2012 May; 44(4):1005-8. doi:
10.1016/j.transproceed.2012.03.050. [PMID: 22564610] - Barbara Dolińska, Aneta Ostróżka-Cieślik, Artur Caban, Lech Cierpka, Florian Ryszka. Comparing the effect of Biolasol® and HTK solutions on maintaining proper homeostasis, indicating the kidney storage efficiency prior to transplantation.
Annals of transplantation.
2012 Apr; 17(2):74-8. doi:
10.12659/aot.883225. [PMID: 22743725] - Jong Hoon Lee, Sung Yeon Hong, Chang-Kwon Oh, You Sun Hong, Hyunee Yim. Kidney transplantation from a donor following cardiac death supported with extracorporeal membrane oxygenation.
Journal of Korean medical science.
2012 Feb; 27(2):115-9. doi:
10.3346/jkms.2012.27.2.115. [PMID: 22323856] - Pramod Kadaba Srinivasan, Shintaro Yagi, Benedict Doorschodt, Kazuyuki Nagai, Mamdouh Afify, Shinji Uemoto, Rene Tolba. Impact of venous systemic oxygen persufflation supplemented with nitric oxide gas on cold-stored, warm ischemia-damaged experimental liver grafts.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
2012 Feb; 18(2):219-25. doi:
10.1002/lt.22442. [PMID: 21987402] - M S El-Shahawi, L A Al Khateeb. Spectrofluorometric determination and chemical speciation of trace concentrations of tungsten species in water using the ion pairing reagent procaine hydrochloride.
Talanta.
2012 Jan; 88(?):587-92. doi:
10.1016/j.talanta.2011.11.039. [PMID: 22265545] - F Ryszka, B Dolińska, A Caban, A Ostróżka-Cieślik, G Budziński, M Krzysztofik, G Oczkowicz, L Cierpka. Hepatoprotective effect of prolactin and cysteine contained in perfusion and preservation solutions on porcine liver stored in simple hypothermia.
Transplantation proceedings.
2011 Oct; 43(8):2882-6. doi:
10.1016/j.transproceed.2011.08.064. [PMID: 21996179] - Simone Hoeger, Georgia Lueg, Charalambos Tsagogiorgas, Michael Schneider, Sonja Theisinger, Bastian Theisinger, Johann Fontana, Ruediger Waldherr, Bernhard K Krämer, Peter Schnuelle, Benito Yard. UW is superior compared with HTK after prolonged preservation of renal grafts.
The Journal of surgical research.
2011 Sep; 170(1):e149-57. doi:
10.1016/j.jss.2011.05.020. [PMID: 21741054] - Haixin Chang, Susan S Suarez. Two distinct Ca(2+) signaling pathways modulate sperm flagellar beating patterns in mice.
Biology of reproduction.
2011 Aug; 85(2):296-305. doi:
10.1095/biolreprod.110.089789. [PMID: 21389347] - Christina Ehlert, Claude Plassard, Sarah Jane Cookson, François Tardieu, Thierry Simonneau. Do pH changes in the leaf apoplast contribute to rapid inhibition of leaf elongation rate by water stress? Comparison of stress responses induced by polyethylene glycol and down-regulation of root hydraulic conductivity.
Plant, cell & environment.
2011 Aug; 34(8):1258-66. doi:
10.1111/j.1365-3040.2011.02326.x. [PMID: 21477119] - Dawit Worku, Sebastian Laluf, Jennifer McGee, Monica Goswami, Keith VanMeter, Douglas P Slakey. P-selectin expression in cold preserved kidneys in University of Wisconsin and histidine-tryptophan-ketoglutarate solutions.
The Journal of surgical research.
2011 Jul; 169(1):125-31. doi:
10.1016/j.jss.2009.09.021. [PMID: 20036384] - Leif Jansson, Per-Ola Carlsson, Birgitta Bodin, Orjan Källskog. Flow distribution during infusion of UW and HTK solution in anaesthetised rats.
Langenbeck's archives of surgery.
2011 Jun; 396(5):677-83. doi:
10.1007/s00423-011-0747-1. [PMID: 21328017] - Milagros García Mesa, Héctor Álvarez Duarte, José Hernández Carretero, Martha M Fors López, Miriam Mahia Vilas. De Marco Formula effectiveness as an adjunctive therapy to prevent infected ischemic diabetic foot amputation and reduce plasma fibrinogen.
Journal of tissue viability.
2011 May; 20(2):67-72. doi:
10.1016/j.jtv.2010.12.003. [PMID: 21211975] - Sungsoo Lee, Chien-Sheng Huang, Tomohiro Kawamura, Norihisa Shigemura, Timothy R Billiar, Atsunori Nakao, Yoshiya Toyoda. Histidine-tryptophan-ketoglutarate or celsior: which is more suitable for cold preservation for cardiac grafts from older donors?.
The Annals of thoracic surgery.
2011 Mar; 91(3):755-63. doi:
10.1016/j.athoracsur.2010.11.024. [PMID: 21352993] - A Caban, B Dolińska, G Oczkowicz, G Budziński, A Ostróżka-Cieślik, M Krzysztofik, L Cierpka, F Ryszka. The effect of HTK solution modification by addition of prolactin on biochemical indices reflecting ischaemic damage to porcine kidney.
Transplantation proceedings.
2010 Dec; 42(10):3981-3. doi:
10.1016/j.transproceed.2010.09.060. [PMID: 21168605] - Sungsoo Lee, Chien-Sheng Huang, Tomohiro Kawamura, Norihisa Shigemura, Donna B Stolz, Timothy R Billiar, James D Luketich, Atsunori Nakao, Yoshiya Toyoda. Superior myocardial preservation with HTK solution over Celsior in rat hearts with prolonged cold ischemia.
Surgery.
2010 Aug; 148(2):463-73. doi:
10.1016/j.surg.2010.04.009. [PMID: 20627336] - Xiaodong Yuan, Ashok J Theruvath, Xupeng Ge, Bernhard Floerchinger, Anke Jurisch, Guillermo García-Cardeña, Stefan G Tullius. Machine perfusion or cold storage in organ transplantation: indication, mechanisms, and future perspectives.
Transplant international : official journal of the European Society for Organ Transplantation.
2010 Jun; 23(6):561-70. doi:
10.1111/j.1432-2277.2009.01047.x. [PMID: 20074082] - J A Fridell, R S Mangus, J A Powelson. Histidine-tryptophan-ketoglutarate for pancreas allograft preservation: the Indiana University experience.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
2010 May; 10(5):1284-9. doi:
10.1111/j.1600-6143.2010.03095.x. [PMID: 20353471] - Wei-Wei Qin, Zheng Jiao, Ming-Kang Zhong, Xiao-Jin Shi, Jun Zhang, Zhong-Dong Li, Xue-Yan Cui. Simultaneous determination of procaine, lidocaine, ropivacaine, tetracaine and bupivacaine in human plasma by high-performance liquid chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2010 May; 878(15-16):1185-9. doi:
10.1016/j.jchromb.2010.03.003. [PMID: 20356808] - Sarah A Hosgood, Bin Yang, Atul Bagul, Ismail H Mohamed, Michael L Nicholson. A comparison of hypothermic machine perfusion versus static cold storage in an experimental model of renal ischemia reperfusion injury.
Transplantation.
2010 Apr; 89(7):830-7. doi:
10.1097/tp.0b013e3181cfa1d2. [PMID: 20098357] - Hong Wang, Ying Zhang, Shi-Tong Li. The effect of local anesthetics on the inhibition of adult muscle-type nicotinic acetylcholine receptors by nondepolarizing muscle relaxants.
European journal of pharmacology.
2010 Mar; 630(1-3):29-33. doi:
10.1016/j.ejphar.2009.12.028. [PMID: 20045405] - Kenneth Drasner. Local anesthetic systemic toxicity: a historical perspective.
Regional anesthesia and pain medicine.
2010 Mar; 35(2):162-6. doi:
10.1097/aap.0b013e3181d2306c. [PMID: 20216034] - M C J M Schreinemachers, B M Doorschodt, S Florquin, M A van den Bergh Weerman, A Zernecke, M M Idu, R H Tolba, T M van Gulik. Pulsatile perfusion preservation of warm ischaemia-damaged experimental kidney grafts.
The British journal of surgery.
2010 Mar; 97(3):349-58. doi:
10.1002/bjs.6879. [PMID: 20095019] - Thomas Puehler, Otto Gleich, Simon Schopka, Leopold Rupprecht, Stephan Hirt, Christof Schmid, Karla Lehle. Impact of normothermic perfusion and protein supplementation on human endothelial cell function during organ preservation.
The Annals of thoracic surgery.
2010 Feb; 89(2):512-20. doi:
10.1016/j.athoracsur.2009.10.037. [PMID: 20103334] - S Kahl, J Mayer, K Schuette, H Peuravuori, M Pross, H U Schulz, T J Nevalainen, P Malfertheiner. Effect of procainhydrochloride on phospholipase A2 catalytic activity in sodium taurocholate-induced acute experimental pancreatitis in rats.
Digestive diseases (Basel, Switzerland).
2010; 28(2):373-8. doi:
10.1159/000319417. [PMID: 20814215] - M C J M Schreinemachers, B M Doorschodt, S Florquin, R H Tolba. Comparison of preservation solutions for washout of kidney grafts: an experimental study.
Transplantation proceedings.
2009 Dec; 41(10):4072-9. doi:
10.1016/j.transproceed.2009.09.089. [PMID: 20005343] - C L Corps, M Shires, D Crellin, R Smolenski, J Pratt, D Potts, J P A Lodge. Histidine-tryptophan-ketoglutarate and delayed graft function after prolonged cold ischemia.
Transplantation proceedings.
2009 Nov; 41(9):3567-70. doi:
10.1016/j.transproceed.2009.04.009. [PMID: 19917345] - Takeshi Fujii, Manabu Masai, Hidemi Misawa, Takashi Okuda, Yuki Takada-Takatori, Yasuhiro Moriwaki, Tatsuya Haga, Koichiro Kawashima. Acetylcholine synthesis and release in NIH3T3 cells coexpressing the high-affinity choline transporter and choline acetyltransferase.
Journal of neuroscience research.
2009 Oct; 87(13):3024-32. doi:
10.1002/jnr.22117. [PMID: 19405101] - Bryon Adinoff, Michael D Devous, Donald C Cooper, Susan E Best, Thomas S Harris, Mark J Williams. Neural response to lidocaine in healthy subjects.
Psychiatry research.
2009 Aug; 173(2):135-42. doi:
10.1016/j.pscychresns.2009.03.001. [PMID: 19560905]