Cefazolin sodium (BioDeep_00000015088)
代谢物信息卡片
Cephazolin sodium
化学式: C14H13N8NaO4S3 (476.01195780000006)
中文名称: 头孢唑啉 钠盐
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=NN=C(S1)SCC2=C(N3C(C(C3=O)NC(=O)CN4C=NN=N4)SC2)C(=O)[O-].[Na+]
InChI: /q
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
同义名列表
2 个代谢物同义名
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:3483
- KEGG: C08098
- KEGGdrug: D00905
- PubChem: 23675322
- ChEMBL: CHEMBL1200523
- MeSH: Cefazolin
- CAS: 27164-46-1
- PubChem: 10298
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xiangyang Lv, Xiaoshuang Ren, Jiqun Xu, Haicui Wu. Effect of prophylactic use of cefazolin in caesarean section on postoperative infection: A meta-analysis.
International wound journal.
2024 Apr; 21(4):e14740. doi:
10.1111/iwj.14740. [PMID: 38522482] - Yannick F Diehm, Emre Gazyakan, Yiping Wang, Laura C Siegwart, Valentin Haug, Dimitra Kotsougiani-Fischer, Ulrich Kneser, Sebastian Fischer. Effective or Harmful-Evaluation of Locally Applied Antibiotics on Adipose Tissue during Lipofilling to the Breast-An In Vitro Study.
International journal of molecular sciences.
2023 Jan; 24(3):. doi:
10.3390/ijms24032323. [PMID: 36768647] - Kyung-Hyo Do, Kwang Won Seo, Jae-Won Byun, Wan-Kyu Lee. Relationship between virulence factors and antimicrobial resistance genes of pathogenic Escherichia coli from diarrheic weaned piglets.
Research in veterinary science.
2022 Dec; 150(?):137-143. doi:
10.1016/j.rvsc.2022.05.007. [PMID: 35830753] - Justin Poltak, Christopher Connors, Minkey Wungwattana, David Nicolau, Nicholas J Mercuro, Jiajun Liu. Pharmacokinetics of Cefazolin in Patients With Obesity Undergoing Surgery Requiring Cardiopulmonary Bypass.
Journal of cardiothoracic and vascular anesthesia.
2022 Aug; 36(8 Pt B):2942-2947. doi:
10.1053/j.jvca.2022.01.029. [PMID: 35227575] - Rochelle L Ryan, Dwane Jackson, George Hopkins, Victoria Eley, Rebecca Christensen, Andre A J Van Zundert, Steven C Wallis, Jeffrey Lipman, Suzanne L Parker, Jason A Roberts. Plasma and Interstitial Fluid Pharmacokinetics of Prophylactic Cefazolin in Elective Bariatric Surgery Patients.
Antimicrobial agents and chemotherapy.
2022 Jul; 66(7):e0041922. doi:
10.1128/aac.00419-22. [PMID: 35762797] - Yuval Fouks, Eran Ashwal, Yariv Yogev, Sharon Amit, Tali Ben Mayor Bashi, Noa Sinai, Anastasia Firsow, Eyal Hasson, Ronni Gamzu, Ariel Many. Calculating the appropriate prophylactic dose of cefazolin in women undergoing cesarean delivery.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.
2022 Jul; 35(13):2518-2523. doi:
10.1080/14767058.2020.1786529. [PMID: 32662688] - Kyung Mi Kim, Jiwon Jung, Jong Min Lee, Hong Seuk Yang, Ji-Yeon Bang, Eun-Kyung Lee, Byung-Moon Choi, Gyu-Jeong Noh. The expected advantage of administering prophylactic antibiotics using target- concentration controlled infusion: Development of a new pharmacokinetic model of cefazolin.
Clinical and experimental pharmacology & physiology.
2022 Jul; 49(7):731-739. doi:
10.1111/1440-1681.13648. [PMID: 35434816] - Anna Siemiątkowska, Andrew Wassef, Ragui Sadek, Celine Park, Christine Yohn, Luigi Brunetti, Leonid Kagan. A validated LC-MS/MS method for the quantitation of cefazolin in human adipose tissue: Application of EMR-Lipid sorbent as an efficient sample clean-up before mass spectrometric analyses.
Journal of pharmaceutical and biomedical analysis.
2022 May; 213(?):114696. doi:
10.1016/j.jpba.2022.114696. [PMID: 35259713] - Kenji Ueki, Akihiro Tsuchimoto, Kumiko Torisu, Kiichiro Fujisaki, Sayaka Tachibana, Keigo Tomita, Toshiaki Nakano, Kazuhiko Tsuruya, Takanari Kitazono. A case of peritoneal dialysis-related peritonitis caused by dialysate leakage with successful treatment by intravenous and intraperitoneal antibiotic therapy.
CEN case reports.
2022 05; 11(2):161-165. doi:
10.1007/s13730-021-00644-4. [PMID: 34510327] - Shunsuke Takahara, Takeo Tokura, Ryota Nishida, Atsuo Uefuji, Katsuhito Ichimura, Hirotaka Nishihara, Kenji Aoki, Hiroyuki Takayama, Natsuko Nakagawa, Toshihiko Harada. Ampicillin/sulbactam versus cefazolin plus aminoglycosides for antimicrobial prophylaxis in management of Gustilo type IIIA open fractures: A retrospective cohort study.
Injury.
2022 Apr; 53(4):1517-1522. doi:
10.1016/j.injury.2022.01.033. [PMID: 35090733] - Joshua A Reeder, Inas A Abdallah, Thanh Bach, Cormac T O'Sullivan, Yan Xu, Demet Nalbant, Guohua An. Development and validation of a simple and sensitive LC-MS/MS method for the quantification of cefazolin in human plasma and its application to a clinical pharmacokinetic study.
Journal of pharmaceutical and biomedical analysis.
2022 Feb; 210(?):114521. doi:
10.1016/j.jpba.2021.114521. [PMID: 34979494] - Radoslaw Jaworski, Katarzyna Dzierzanowska-Fangrat, Agnieszka Czajkowska, Bohdan Maruszewski, Andrzej Kansy. Cefazolin prophylaxis in children undergoing cardiac surgery with the use of cardiopulmonary bypass-is the dosing correct?.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.
2021 Dec; 61(1):27-33. doi:
10.1093/ejcts/ezab251. [PMID: 34269390] - Natalia E Castillo Almeida, Ryan W Stevens, Pooja Gurram, Christina G Rivera, Gina A Suh. Cefazolin and rifampin: A coagulopathy-inducing combination.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
2021 12; 78(24):2204-2208. doi:
10.1093/ajhp/zxab210. [PMID: 34000006] - B Lefèvre, B Hoen, F Goehringer, W Ngueyon Sime, N Aissa, C Alauzet, E Jeanmaire, S Hénard, L Filippetti, C Selton-Suty, N Agrinier. Antistaphylococcal penicillins vs. cefazolin in the treatment of methicillin-susceptible Staphylococcus aureus infective endocarditis: a quasi-experimental monocentre study.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
2021 Dec; 40(12):2605-2616. doi:
10.1007/s10096-021-04313-3. [PMID: 34383175] - Omar Elkayal, Karel Allegaert, Isabel Spriet, Anne Smits, Marie-Christine Seghaye, Corinne Charlier, Erwin Dreesen. Population pharmacokinetics of cefazolin in maternal and umbilical cord plasma, and simulated exposure in term neonates.
The Journal of antimicrobial chemotherapy.
2021 11; 76(12):3229-3236. doi:
10.1093/jac/dkab329. [PMID: 34499720] - Taisuke Kuroda, Yohei Minamijima, Hidekazu Niwa, Norihisa Tamura, Hiroshi Mita, Kentaro Fukuda, Masahiro Kaimachi, Yuto Suzuki, Yuki Enoki, Kazuaki Taguchi, Kazuaki Matsumoto, Pierre-Louis Toutain, Alain Bousquet-Melou, Yoshinori Kasashima. Rational dosage regimens for cephalothin and cefazolin using pharmacokinetics and pharmacodynamics analysis in healthy horses.
Equine veterinary journal.
2021 Nov; 53(6):1239-1249. doi:
10.1111/evj.13406. [PMID: 33341979] - Daniel J Selig, Geoffrey C Chin, Alexander G Bobrov, Jesse P DeLuca, Derese Getnet, Jeffrey R Livezey, Joseph B Long, Venkatasivasai S Sajja, Brett E Swierczewski, Stuart D Tyner, Vlado Antonic. Semimechanistic Modeling of the Effects of Blast Overpressure Exposure on Cefazolin Pharmacokinetics in Mice.
The Journal of pharmacology and experimental therapeutics.
2021 11; 379(2):175-181. doi:
10.1124/jpet.121.000797. [PMID: 34433578] - Michael Lavie, Inbar Lavie, Aviad Cohen, Ishai Levin, Ariel Many, Yuval Fouks. Cefazolin prophylaxis in minimally invasive gynecologic surgery - are dosage and timing appropriate? Prospective study using resampling simulation.
Journal of gynecology obstetrics and human reproduction.
2021 Nov; 50(9):102154. doi:
10.1016/j.jogoh.2021.102154. [PMID: 33905919] - S V Valiulin, A A Onischuk, A M Baklanov, S N Dubtsov, S V An'kov, N N Shkil, E V Nefedova, M E Plokhotnichenko, T G Tolstikova, A M Dolgov, G G Dultseva. Aerosol inhalation delivery of cefazolin in mice: Pharmacokinetic measurements and antibacterial effect.
International journal of pharmaceutics.
2021 Sep; 607(?):121013. doi:
10.1016/j.ijpharm.2021.121013. [PMID: 34419591] - Hendrik Booke, Otto R Frey, Anka C Röhr, Ute Chiriac, Kai Zacharowski, Tomas Holubec, Elisabeth H Adam. Excessive unbound cefazolin concentrations in critically ill patients receiving veno-arterial extracorporeal membrane oxygenation (vaECMO): an observational study.
Scientific reports.
2021 08; 11(1):16981. doi:
10.1038/s41598-021-96654-4. [PMID: 34417526] - Orlando Salinas-Jaramillo, Alejandra Monroy-Arreola, Sebastian Herrera-Noreña, Ana L Guzmán-Ortiz, Abrahan Hernández-Hernández, Silvia Méndez-Flores, Judith Domínguez-Cherit, Noe V Duran-Figueroa, Dean J Naisbitt, Pedro Cortes-Reynosa, Eduardo Perez Salazar, Héctor Quezada, J Luis Castrejón-Flores. Extracellular Vesicles from Human Plasma Show a Distinctive Proteome and miRNome Profile in Patients with Severe Cutaneous Adverse Reactions.
Chemical research in toxicology.
2021 07; 34(7):1738-1748. doi:
10.1021/acs.chemrestox.1c00047. [PMID: 34142820] - Christoph Dorn, David Petroff, Melanie Stoelzel, Martin G Kees, Alexander Kratzer, Arne Dietrich, Charlotte Kloft, Markus Zeitlinger, Frieder Kees, Hermann Wrigge, Philipp Simon. Perioperative administration of cefazolin and metronidazole in obese and non-obese patients: a pharmacokinetic study in plasma and interstitial fluid.
The Journal of antimicrobial chemotherapy.
2021 07; 76(8):2114-2120. doi:
10.1093/jac/dkab143. [PMID: 33969405] - Ke Xu Szeto, Maxime Le Merdy, Benjamin Dupont, Michael B Bolger, Viera Lukacova. PBPK Modeling Approach to Predict the Behavior of Drugs Cleared by Kidney in Pregnant Subjects and Fetus.
The AAPS journal.
2021 06; 23(4):89. doi:
10.1208/s12248-021-00603-y. [PMID: 34169370] - Hengqing Gao, Xiaohong Cheng, Runping Liu, Xiaoqiang Wang, Wei Wang, Furao Gong, Renping Pan, Jing Hu. Clinical study of herbal mixture 'Diding Oral Medicine' as an alternative to preventative antibiotics in perioperative hemorrhoids: A CARE-compliant article.
Medicine.
2021 May; 100(18):e25661. doi:
10.1097/md.0000000000025661. [PMID: 33950943] - Sînziana Cristea, Elke H J Krekels, Karel Allegaert, Peter De Paepe, Annick de Jaeger, Pieter De Cock, Catherijne A J Knibbe. Estimation of Ontogeny Functions for Renal Transporters Using a Combined Population Pharmacokinetic and Physiology-Based Pharmacokinetic Approach: Application to OAT1,3.
The AAPS journal.
2021 05; 23(3):65. doi:
10.1208/s12248-021-00595-9. [PMID: 33948771] - Michael L Schmitz, Christopher M Rubino, Nikolas J Onufrak, Diana Valencia Martinez, Diane Licursi, Angela Karpf, Wes Cetnarowski. Pharmacokinetics and Optimal Dose Selection of Cefazolin for Surgical Prophylaxis of Pediatric Patients.
Journal of clinical pharmacology.
2021 05; 61(5):666-676. doi:
10.1002/jcph.1785. [PMID: 33202066] - Mizuho Asada, Masashi Nagata, Tomohiro Mizuno, Tokujiro Uchida, Hiromitsu Takahashi, Koshi Makita, Hirokuni Arai, Shinichi Kijima, Hirotoshi Echizen, Masato Yasuhara. Population pharmacokinetics of cefazolin before, during and after cardiopulmonary bypass in adult patients undergoing cardiac surgery.
European journal of clinical pharmacology.
2021 May; 77(5):735-745. doi:
10.1007/s00228-020-03045-1. [PMID: 33211137] - Saowaphak Lapmahapaisan, Wiriya Maisat, Kriangkrai Tantiwongkosri, Pinpilai Jutasompakorn, Waraphorn Sisan. Plasma concentrations of cefazolin in pediatric patients undergoing cardiac surgery.
Annals of cardiac anaesthesia.
2021 Apr; 24(2):149-154. doi:
10.4103/aca.aca_106_19. [PMID: 33884969] - Toshiki Etani, Minami Asaoka, Shuhei Kondo, Chiharu Wachino, Kaoru Hori, Nobuhiko Shimizu, Yusuke Noda, Takashi Nagai, Satoshi Nozaki, Keitaro Iida, Taku Naiki, Ryosuke Ando, Noriyasu Kawai, Takeshi Yanagita, Atsushi Nakamura, Takahiro Yasui. Efficacy of fosfomycin in the prevention of postoperative infection following transurethral resection of bladder tumor during periods of limited cefazolin, cefotiam, and cefmetazole supply.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2021 Apr; 27(4):625-631. doi:
10.1016/j.jiac.2020.11.025. [PMID: 33309628] - Naruaki Imoto, Chie Kano, Yumi Aoyagi, Hiroto Morita, Fumitaka Amanuma, Hidekazu Maruyama, Shuko Nojiri, Naoyuki Hashiguchi, Shin Watanabe. Administration of β-lactam antibiotics and delivery method correlate with intestinal abundances of Bifidobacteria and Bacteroides in early infancy, in Japan.
Scientific reports.
2021 03; 11(1):6231. doi:
10.1038/s41598-021-85670-z. [PMID: 33737648] - Toshiaki Komatsu, Yui Natsume, Katsufumi Uchiyama, Shinsuke Ikeda, Yoshinori Tomoda, Yoko Takayama, Masashi Takaso, Hideaki Hanaki, Koichiro Atsuda. Population Pharmacokinetic and Pharmacodynamic Target Attainment Analysis of Cefazolin in the Serum and Hip Joint Capsule of Patients Undergoing Total Hip Arthroplasty.
Antimicrobial agents and chemotherapy.
2021 03; 65(4):. doi:
10.1128/aac.02114-20. [PMID: 33526489] - E Salvador, M Oualha, E Bille, A Beranger, F Moulin, S Benaboud, S Boujaafar, I Gana, S Urien, Y Zheng, J Toubiana, C Briand, O Bustarret, G Geslain, S Renolleau, J-M Treluyer, D Hirt. Population pharmacokinetics of cefazolin in critically ill children infected with methicillin-sensitive Staphylococcus aureus.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
2021 Mar; 27(3):413-419. doi:
10.1016/j.cmi.2020.04.022. [PMID: 32360445] - Zhi Xu. 1,2,3-Triazole-containing hybrids with potential antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).
European journal of medicinal chemistry.
2020 Nov; 206(?):112686. doi:
10.1016/j.ejmech.2020.112686. [PMID: 32795773] - Akane Yamabe, Atsushi Irisawa, Hiroto Wakabayashi, Takuya Tsunoda, Keiichi Tominaga. Ceftriaxone-associated Pseudolithiasis in the Gallbladder and Bile Duct of an Elderly Patient.
Internal medicine (Tokyo, Japan).
2020 Nov; 59(21):2725-2728. doi:
10.2169/internalmedicine.4672-20. [PMID: 32669492] - Norihito Kaku, Nariyoshi Matsumoto, Daisuke Sasaki, Keiichi Tsuda, Kosuke Kosai, Naoki Uno, Yoshitomo Morinaga, Atsushi Tagami, Shinji Adachi, Hiroo Hasegawa, Makoto Osaki, Katsunori Yanagihara. Effect of probiotics on gut microbiome in patients with administration of surgical antibiotic prophylaxis: A randomized controlled study.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2020 Aug; 26(8):795-801. doi:
10.1016/j.jiac.2020.03.008. [PMID: 32284181] - Karel Allegaert, Anouk E Muller, Francesca Russo, Sam Schoenmakers, Jan Deprest, Birgit C P Koch. Pregnancy-related pharmacokinetics and antimicrobial prophylaxis during fetal surgery, cefazolin and clindamycin as examples.
Prenatal diagnosis.
2020 08; 40(9):1178-1184. doi:
10.1002/pd.5753. [PMID: 32441341] - Victoria A Eley, Rebecca Christensen, Rochelle Ryan, Dwane Jackson, Suzanne L Parker, Matthew Smith, Andre A van Zundert, Steven C Wallis, Jeffrey Lipman, Jason A Roberts. Prophylactic Cefazolin Dosing in Women With Body Mass Index >35 kg·m-2 Undergoing Cesarean Delivery: A Pharmacokinetic Study of Plasma and Interstitial Fluid.
Anesthesia and analgesia.
2020 07; 131(1):199-207. doi:
10.1213/ane.0000000000004766. [PMID: 32250982] - Lynn Chan, Noreen H Chan-Tompkins, James Como, Anthony J Guarascio. Retrospective Analysis of Adverse Drug Events Between Nafcillin Versus Cefazolin for Treatment of Methicillin-Susceptible Staphylococcus aureus Infections.
The Annals of pharmacotherapy.
2020 07; 54(7):662-668. doi:
10.1177/1060028019897267. [PMID: 31888347] - Pınar Güller, Harun Budak, Melda Şişecioğlu, Mehmet Çiftci. An in vivo and in vitro comparison of the effects of amoxicillin, gentamicin, and cefazolin sodium antibiotics on the mouse hepatic and renal glutathione reductase enzyme.
Journal of biochemical and molecular toxicology.
2020 Jul; 34(7):e22496. doi:
10.1002/jbt.22496. [PMID: 32196862] - M Penven, A Lalieu, A Boruchowicz, M Paluch, T Diedrich, G Dewulf, C Cattoen. Bacteremia caused by Elizabethkingia miricola in a patient with acute pancreatitis and peritoneal dialysis.
Medecine et maladies infectieuses.
2020 Jun; 50(4):379-381. doi:
10.1016/j.medmal.2020.01.009. [PMID: 32046885] - Joseph M Blondeau, Shantelle D Fitch. In vitro killing of canine strains of Staphylococcus pseudintermedius and Escherichia coli by cefazolin, cefovecin, doxycycline and pradofloxacin over a range of bacterial densities.
Veterinary dermatology.
2020 Jun; 31(3):187-e39. doi:
10.1111/vde.12835. [PMID: 31825131] - Gerdien A Zeilmaker-Roest, Annewil van Saet, Marloes P J van Hoeven, Birgit C P Koch, Joost van Rosmalen, Martina Kinzig, Fritz Söergel, Enno D Wildschut, Robert J Stolker, Dick Tibboel, Ad J J C Bogers. Recovery of cefazolin and clindamycin in in vitro pediatric CPB systems.
Artificial organs.
2020 Apr; 44(4):394-401. doi:
10.1111/aor.13595. [PMID: 31693189] - Wenjie Lou, Kai Zou, Zhongbin Yu, Song Qin, Kai Wang, Biao Che. Cefazolin sodium pentahydrate combined with vacuum sealing drainage in the treatment of open fracture complicated with soft tissue injury.
Revista da Associacao Medica Brasileira (1992).
2020 Apr; 66(4):430-436. doi:
10.1590/1806-9282.66.4.430. [PMID: 32578775] - Pinpongsarn Triyawatanyu, Pajaree Chariyavilaskul, Weeraya Phaisal, Sadudee Peerapornratana, Talerngsak Kanjanabuch, Kearkiat Praditpornsilpa, Pisut Katavetin. Intraperitoneal cefazolin and ceftazidime during short-dwell exchange in peritoneal dialysis patients with peritonitis.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2020 03; 40(2):179-184. doi:
10.1177/0896860819893820. [PMID: 32063189] - Steven Y C Tong, David C Lye, Dafna Yahav, Archana Sud, J Owen Robinson, Jane Nelson, Sophia Archuleta, Matthew A Roberts, Alan Cass, David L Paterson, Hong Foo, Mical Paul, Stephen D Guy, Adrian R Tramontana, Genevieve B Walls, Stephen McBride, Narin Bak, Niladri Ghosh, Benjamin A Rogers, Anna P Ralph, Jane Davies, Patricia E Ferguson, Ravindra Dotel, Genevieve L McKew, Timothy J Gray, Natasha E Holmes, Simon Smith, Morgyn S Warner, Shirin Kalimuddin, Barnaby E Young, Naomi Runnegar, David N Andresen, Nicholas A Anagnostou, Sandra A Johnson, Mark D Chatfield, Allen C Cheng, Vance G Fowler, Benjamin P Howden, Niamh Meagher, David J Price, Sebastiaan J van Hal, Matthew V N O'Sullivan, Joshua S Davis. Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial.
JAMA.
2020 02; 323(6):527-537. doi:
10.1001/jama.2020.0103. [PMID: 32044943] - Jesus M Villa, Tejbir S Pannu, Aldo M Riesgo, Preetesh D Patel, Michael A Mont, Carlos A Higuera-Rueda. Dual Antibiotic Prophylaxis in Total Knee Arthroplasty: Where Do We Stand?.
The journal of knee surgery.
2020 Feb; 33(2):100-105. doi:
10.1055/s-0039-1695742. [PMID: 31470454] - Vlado Antonic, Venkatasivasaisujith Sajja, Jason Sousa, Ken Nguyen, Yonas Alamneh, Brittany Garry, Maria Medina-Rojas, Donna Wilder, Chau Vuong, Brittney Potter, Daniel Zurawski, Jonathan Shearer, Chad Black, Samandra Demons, Joseph Long, Stuart Tyner. Evaluation of Blast Overpressure Exposure Effects on Concentration of Antibiotics in Mice.
Military medicine.
2020 01; 185(Suppl 1):256-262. doi:
10.1093/milmed/usz212. [PMID: 32074328] - Fikret Türkan, Zübeyir Huyut, Yıldıray Basbugan, İlhami Gülçin. Influence of some β-lactam drugs on selected antioxidant enzyme and lipid peroxidation levels in different rat tissues.
Drug and chemical toxicology.
2020 Jan; 43(1):27-36. doi:
10.1080/01480545.2019.1608230. [PMID: 31060396] - Trisha Peel, Sarah Astbury, Allen C Cheng, David Paterson, Kirsty Buising, Tim Spelman, An Tran-Duy, Richard S de Steiger. Multicentre randomised double-blind placebo controlled trial of combination vancomycin and cefazolin surgical antibiotic prophylaxis: the Australian surgical antibiotic prophylaxis (ASAP) trial.
BMJ open.
2019 11; 9(11):e033718. doi:
10.1136/bmjopen-2019-033718. [PMID: 31685516] - Thidarat Kitrungphaiboon, Pongpratch Puapatanakul, Piyatida Chuengsaman, Krittaya Tiskajornsiri, Guttiga Halue, Monchai Siribamrungwong, Saraporn Matayart, Kamonrat Chongthanakorn, Ussanee Poonvivatchaikarn, Chanchana Boonyakrai, Wanida Somboonsilp, Pisut Katavetin, Kearkiat Praditpornsilpa, Somchai Eiam-Ong, David W Johnson, Talerngsak Kanjanabuch. Intraperitoneal Cefepime Monotherapy Versus Combination Therapy of Cefazolin Plus Ceftazidime for Empirical Treatment of CAPD-Associated Peritonitis: A Multicenter, Open-Label, Noninferiority, Randomized, Controlled Trial.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2019 11; 74(5):601-609. doi:
10.1053/j.ajkd.2019.05.011. [PMID: 31331757] - Muthana Al Sahlawi, Adrian Liew, Jeffrey Perl. Cefepime as Empirical Peritoneal Dialysis-Associated Peritonitis Treatment: Something to Dwell On?.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2019 11; 74(5):579-582. doi:
10.1053/j.ajkd.2019.06.008. [PMID: 31515138] - Ronan Bellouard, Colin Deschanvres, Guillaume Deslandes, Éric Dailly, Nathalie Asseray, Pascale Jolliet, David Boutoille, Benjamin Gaborit, Matthieu Grégoire. Population Pharmacokinetic Study of Cefazolin Dosage Adaptation in Bacteremia and Infective Endocarditis Based on a Nomogram.
Antimicrobial agents and chemotherapy.
2019 10; 63(10):. doi:
10.1128/aac.00806-19. [PMID: 31307987] - Sharon Blum, Cheston B Cunha, Burke A Cunha. Lack of Pharmacokinetic Basis of Weight-Based Dosing and Intra-Operative Re-Dosing with Cefazolin Surgical Prophylaxis in Obese Patients: Implications for Antibiotic Stewardship.
Surgical infections.
2019 Sep; 20(6):439-443. doi:
10.1089/sur.2019.039. [PMID: 31112072] - Gemma Sanclemente, Marta Bodro, Carlos Cervera, Laura Linares, Frederic Cofán, Francesc Marco, Jordi Bosch, Federico Oppenheimer, Fritz Dieckmann, Asunción Moreno. Perioperative prophylaxis with ertapenem reduced infections caused by extended-spectrum betalactamase-producting Enterobacteriaceae after kidney transplantation.
BMC nephrology.
2019 07; 20(1):274. doi:
10.1186/s12882-019-1461-4. [PMID: 31331289] - Christoph Dorn, Alexander Kratzer, Selina Schießer, Frieder Kees, Hermann Wrigge, Philipp Simon. Determination of total or free cefazolin and metronidazole in human plasma or interstitial fluid by HPLC-UV for pharmacokinetic studies in man.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2019 Jun; 1118-1119(?):51-54. doi:
10.1016/j.jchromb.2019.04.025. [PMID: 31005774] - Sarah K Dotters-Katz, Marcela C Smid, Matthew R Grace, Ravindu P Gunatilake, Craig Sykes, Kimberly Blake, Kim A Boggess, Avinash S Patil, Tracy Manuck. The Effect of Blood Loss on Cefazolin Levels in Women Undergoing Cesarean Delivery.
American journal of perinatology.
2019 06; 36(7):688-694. doi:
10.1055/s-0038-1673654. [PMID: 30336498] - Friederike Bachmann, Thomas Adam, Frank Friedersdorff, Lutz Liefeldt, Torsten Slowinski, Klemens Budde, Johannes Waiser. Perioperative antibiotic prophylaxis in renal transplantation: a single-center comparison between two regimens and a brief survey among the Eurotransplant renal transplantation centers.
World journal of urology.
2019 May; 37(5):957-967. doi:
10.1007/s00345-018-2440-2. [PMID: 30109484] - Jerry Ingrande, Kathleen Gutierrez, Hendrikus J Lemmens, Archana Verma, David P Nicolau, Christina A Sutherland, Chandra Ramamoorthy. Pharmacokinetics of Cefazolin and Vancomycin in Infants Undergoing Open-Heart Surgery With Cardiopulmonary Bypass.
Anesthesia and analgesia.
2019 05; 128(5):935-943. doi:
10.1213/ane.0000000000003876. [PMID: 30995208] - Hajar AlQahtani, Fulwah Y Alqahtani, Fadilah S Aleanizy, Saeed Baloch, Deanne Tabb. IgA Nephropathy Flare-Up Mimicking Staphylococcus Post-Infection Glomerulonephritis in Patient with Staphylococcus Aureus Infection Treated with Cefazolin: A Case Report and Brief Review of the Literature.
The American journal of case reports.
2019 Apr; 20(?):508-510. doi:
10.12659/ajcr.914935. [PMID: 30978177] - Fortuné M K Elekonawo, Manon M D van der Meeren, Geert A Simkens, Johannes H W de Wilt, Ignace H de Hingh, Andreas J A Bremers. Comparison of 2 Perioperative Management Protocols and Their Influence on Postoperative Recovery after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Standard Parenteral Nutrition, Selective Bowel Decontamination and Suprapubic Catheters?.
Digestive surgery.
2019; 36(5):394-401. doi:
10.1159/000490068. [PMID: 29982248] - Mei Zhang, Grant A Moore, Paul K L Chin, Richard Everts, Evan J Begg. Simultaneous Determination of Cefalexin, Cefazolin, Flucloxacillin, and Probenecid by Liquid Chromatography-Tandem Mass Spectrometry for Total and Unbound Concentrations in Human Plasma.
Therapeutic drug monitoring.
2018 12; 40(6):682-692. doi:
10.1097/ftd.0000000000000555. [PMID: 30015652] - Mizuho Asada, Masashi Nagata, Tomohiro Mizuno, Tokujiro Uchida, Naoki Kurashima, Hiromitsu Takahashi, Koshi Makita, Hirokuni Arai, Hirotoshi Echizen, Masato Yasuhara. Effects of cardiopulmonary bypass on the disposition of cefazolin in patients undergoing cardiothoracic surgery.
Pharmacology research & perspectives.
2018 12; 6(6):e00440. doi:
10.1002/prp2.440. [PMID: 30410768] - Sheryl A Zelenitsky, Divna Calic, Rakesh C Arora, Hilary P Grocott, Ted M Lakowski, Ryan Lillico, Robert E Ariano. Antimicrobial Prophylaxis for Patients Undergoing Cardiac Surgery: Intraoperative Cefazolin Concentrations and Sternal Wound Infections.
Antimicrobial agents and chemotherapy.
2018 11; 62(11):. doi:
10.1128/aac.01360-18. [PMID: 30150469] - Robert B Flint, Soma Bahmany, Bart C H van der Nagel, Birgit C P Koch. Simultaneous quantification of fentanyl, sufentanil, cefazolin, doxapram and keto-doxapram in plasma using liquid chromatography-tandem mass spectrometry.
Biomedical chromatography : BMC.
2018 Oct; 32(10):e4290. doi:
10.1002/bmc.4290. [PMID: 29768657] - Sheryl A Zelenitsky, Divna Calic, Robert E Ariano. Evaluation of cefazolin antimicrobial prophylaxis during cardiac surgery with cardiopulmonary bypass-authors' response.
The Journal of antimicrobial chemotherapy.
2018 09; 73(9):2588. doi:
10.1093/jac/dky249. [PMID: 29945163] - Marguerite L Monogue, Jessica K Ortwine, Wenjing Wei, Khalid Eljaaly, Kavita P Bhavan. Nafcillin versus cefazolin for the treatment of methicillin-susceptible Staphylococcus aureus bacteremia.
Journal of infection and public health.
2018 Sep; 11(5):727-731. doi:
10.1016/j.jiph.2018.02.004. [PMID: 29526442] - Peng Liang, Weiran Shan, Zhiyi Zuo. Perioperative use of cefazolin ameliorates postoperative cognitive dysfunction but induces gut inflammation in mice.
Journal of neuroinflammation.
2018 Aug; 15(1):235. doi:
10.1186/s12974-018-1274-6. [PMID: 30134985] - Eduardo Celia Palma, João Victor Laureano, Bibiana Verlindo de Araújo, Nelson Guardiola Meinhardt, Airton Tetelbom Stein, Teresa Dalla Costa. Fast and sensitive HPLC/UV method for cefazolin quantification in plasma and subcutaneous tissue microdialysate of humans and rodents applied to pharmacokinetic studies in obese individuals.
Biomedical chromatography : BMC.
2018 Aug; 32(8):e4254. doi:
10.1002/bmc.4254. [PMID: 29656496] - John R Burger, Benjamin J Hansen, Emily V Leary, Ajay Aggarwal, James A Keeney. Dual-Agent Antibiotic Prophylaxis Using a Single Preoperative Vancomycin Dose Effectively Reduces Prosthetic Joint Infection Rates With Minimal Renal Toxicity Risk.
The Journal of arthroplasty.
2018 07; 33(7S):S213-S218. doi:
10.1016/j.arth.2018.03.009. [PMID: 29656981] - R Cinotti, R Dumont, L Ronchi, A Roquilly, V Atthar, M Grégoire, L Planche, E Letessier, E Dailly, K Asehnoune. Cefazolin tissue concentrations with a prophylactic dose administered before sleeve gastrectomy in obese patients: a single centre study in 116 patients.
British journal of anaesthesia.
2018 Jun; 120(6):1202-1208. doi:
10.1016/j.bja.2017.10.023. [PMID: 29793587] - Eduardo Celia Palma, Nelson Guardiola Meinhardt, Airton Tetelbom Stein, Isabela Heineck, Maria Isabel Fischer, BibianaVerlindo de Araújo, Teresa Dalla Costa. Efficacious Cefazolin Prophylactic Dose for Morbidly Obese Women Undergoing Bariatric Surgery Based on Evidence from Subcutaneous Microdialysis and Populational Pharmacokinetic Modeling.
Pharmaceutical research.
2018 Apr; 35(6):116. doi:
10.1007/s11095-018-2394-5. [PMID: 29644481] - Genia Dubrovsky, Nhan Huynh, Joshua D Rouch, John P Koulakis, David P Nicolau, Christina A Sutherland, Seth Putterman, James C Y Dunn. Subcutaneous cefazolin to reduce surgical site infections in a porcine model.
The Journal of surgical research.
2018 04; 224(?):156-159. doi:
10.1016/j.jss.2017.11.056. [PMID: 29506833] - Yothin Teethaisong, Thippawan Pimchan, Rungrudee Srisawat, Glyn Hobbs, Griangsak Eumkeb. Boesenbergia rotunda (L.) Mansf. extract potentiates the antibacterial activity of some β-lactams against β-lactam-resistant staphylococci.
Journal of global antimicrobial resistance.
2018 03; 12(?):207-213. doi:
10.1016/j.jgar.2017.10.019. [PMID: 29102774] - Fikret Türkan, Zübeyir Huyut, Parham Taslimi, İlhami Gülçin. The in vivo effects of cefazolin, cefuroxime, and cefoperazon on the carbonic anhydrase in different rat tissues.
Journal of biochemical and molecular toxicology.
2018 Mar; 32(3):e22041. doi:
10.1002/jbt.22041. [PMID: 29457666] - Bülent Şengül, Şükrü Beydemir. The interactions of cephalosporins on polyol pathway enzymes from sheep kidney.
Archives of physiology and biochemistry.
2018 Feb; 124(1):35-44. doi:
10.1080/13813455.2017.1358749. [PMID: 28758816] - Valerie Corvalán, Beatrice Hervé, Camila Sanhueza, Nicolás Martínez, María Almonacid, Sebastián De La Fuente. [Susceptibility to first-generation Cephalosporins in Enterobacteriaceae isolated from urine culture according to CLSI and EUCAST breakpoints].
Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia.
2018 ; 35(3):329-331. doi:
10.4067/s0716-10182018000300329. [PMID: 30534916] - Corey C Burrelli, Eleanor K Broadbent, Alice Margulis, Graham M Snyder, Howard S Gold, Christopher McCoy, Monica V Mahoney, Elizabeth B Hirsch. Does the Beta-Lactam Matter? Nafcillin versus Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bloodstream Infections.
Chemotherapy.
2018; 63(6):345-351. doi:
10.1159/000499033. [PMID: 30965335] - Manouk Backes, Siem A Dingemans, Marcel G W Dijkgraaf, H Rogier van den Berg, Bart van Dijkman, Jochem M Hoogendoorn, Pieter Joosse, Ewan D Ritchie, W Herbert Roerdink, Judith P M Schots, Nico L Sosef, Ingrid J B Spijkerman, Bas A Twigt, Alexander H van der Veen, Ruben N van Veen, Jefrey Vermeulen, Dagmar I Vos, Jasper Winkelhagen, J Carel Goslings, Tim Schepers. Effect of Antibiotic Prophylaxis on Surgical Site Infections Following Removal of Orthopedic Implants Used for Treatment of Foot, Ankle, and Lower Leg Fractures: A Randomized Clinical Trial.
JAMA.
2017 12; 318(24):2438-2445. doi:
10.1001/jama.2017.19343. [PMID: 29279933] - André Dallmann, Ibrahim Ince, Juri Solodenko, Michaela Meyer, Stefan Willmann, Thomas Eissing, Georg Hempel. Physiologically Based Pharmacokinetic Modeling of Renally Cleared Drugs in Pregnant Women.
Clinical pharmacokinetics.
2017 12; 56(12):1525-1541. doi:
10.1007/s40262-017-0538-0. [PMID: 28391404] - Htay Htay, Yeoungjee Cho, Elaine M Pascoe, Darsy Darssan, Carmel Hawley, Philip A Clayton, Monique Borlace, Sunil V Badve, Kamal Sud, Neil Boudville, Stephen P McDonald, David W Johnson. Outcomes of Corynebacterium Peritonitis: A Multicenter Registry Analysis.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2017 Nov; 37(6):619-626. doi:
10.3747/pdi.2017.00028. [PMID: 28698253] - Gabriela A Albarellos, Laura Montoya, Sabrina M Passini, Martín P Lupi, Paula M Lorenzini, María F Landoni. Cefazolin pharmacokinetics in cats under surgical conditions.
Journal of feline medicine and surgery.
2017 Oct; 19(10):992-997. doi:
10.1177/1098612x16666594. [PMID: 27609113] - S Jorgensen, M Zurayk, S Yeung, J Terry, M Dunn, P Nieberg, A Wong-Beringer. Emergency Department Urinary Antibiograms Differ by Specific Patient Group.
Journal of clinical microbiology.
2017 09; 55(9):2629-2636. doi:
10.1128/jcm.00481-17. [PMID: 28615465] - Lorie M Harper, Meredith Kilgore, Jeff M Szychowski, William W Andrews, Alan T N Tita. Economic Evaluation of Adjunctive Azithromycin Prophylaxis for Cesarean Delivery.
Obstetrics and gynecology.
2017 08; 130(2):328-334. doi:
10.1097/aog.0000000000002129. [PMID: 28697108] - Evaggelos Kiriazopoulos, Sabina Zaharaki, Ariadni Vonaparti, Panagiota Vourna, Eirini Panteri-Petratou, Dimitra Gennimata, Kara Lombardo, Irene Panderi. Quantification of three beta-lactam antibiotics in breast milk and human plasma by hydrophilic interaction liquid chromatography/positive-ion electrospray ionization mass spectrometry.
Drug testing and analysis.
2017 Jul; 9(7):1062-1072. doi:
10.1002/dta.2104. [PMID: 27714984] - Michael M Kheir, Timothy L Tan, Ibrahim Azboy, Dean D Tan, Javad Parvizi. Vancomycin Prophylaxis for Total Joint Arthroplasty: Incorrectly Dosed and Has a Higher Rate of Periprosthetic Infection Than Cefazolin.
Clinical orthopaedics and related research.
2017 Jul; 475(7):1767-1774. doi:
10.1007/s11999-017-5302-0. [PMID: 28401341] - R Bruch, C Chatelle, A Kling, B Rebmann, S Wirth, S Schumann, W Weber, C Dincer, G Urban. Clinical on-site monitoring of ß-lactam antibiotics for a personalized antibiotherapy.
Scientific reports.
2017 06; 7(1):3127. doi:
10.1038/s41598-017-03338-z. [PMID: 28600499] - Mordechai Grupper, Joseph L Kuti, Morgan L Swank, Lindsay Maggio, Brenna L Hughes, David P Nicolau. Population Pharmacokinetics of Cefazolin in Serum and Adipose Tissue From Overweight and Obese Women Undergoing Cesarean Delivery.
Journal of clinical pharmacology.
2017 06; 57(6):712-719. doi:
10.1002/jcph.851. [PMID: 27925657] - B I Naik, C Roger, K Ikeda, M S Todorovic, S C Wallis, J Lipman, J A Roberts. Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial.
British journal of anaesthesia.
2017 Jun; 118(6):876-882. doi:
10.1093/bja/aex026. [PMID: 28505360] - Daniel B Chastain, Ijang Ngando, Christopher M Bland, Carlos Franco-Paredes, W Anthony Hawkins. Effect of the 2014 Clinical and Laboratory Standards Institute urine-specific breakpoints on cefazolin susceptibility rates at a community teaching hospital.
Annals of clinical microbiology and antimicrobials.
2017 May; 16(1):43. doi:
10.1186/s12941-017-0217-x. [PMID: 28558707] - Sadudee Peerapornratana, Pajaree Chariyavilaskul, Talerngsak Kanjanabuch, Kearkiat Praditpornsilpa, Somchai Eiam-Ong, Pisut Katavetin. Short-Dwell Cycling Intraperitoneal Cefazolin Plus Ceftazidime in Peritoneal Dialysis Patients.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2017 Mar; 37(2):218-224. doi:
10.3747/pdi.2015.00300. [PMID: 27738089] - Pieter A J G De Cock, Hussain Mulla, Sarah Desmet, Filip De Somer, Brett C McWhinney, Jacobus P J Ungerer, Annelies Moerman, Sabrina Commeyne, Johan Vande Walle, Katrien Francois, Johan G C Van Hasselt, Peter De Paepe. Population pharmacokinetics of cefazolin before, during and after cardiopulmonary bypass to optimize dosing regimens for children undergoing cardiac surgery.
The Journal of antimicrobial chemotherapy.
2017 03; 72(3):791-800. doi:
10.1093/jac/dkw496. [PMID: 27999040] - Xing Chen, Collin E M Brathwaite, Alexander Barkan, Keneth Hall, Gloria Chu, Patricia Cherasard, Shan Wang, David P Nicolau, Shahidul Islam, Burke A Cunha. Optimal Cefazolin Prophylactic Dosing for Bariatric Surgery: No Need for Higher Doses or Intraoperative Redosing.
Obesity surgery.
2017 03; 27(3):626-629. doi:
10.1007/s11695-016-2331-9. [PMID: 27520693] - Cuong V Nguyen, Daniel D Miller. Serum sickness-like drug reaction: two cases with a neutrophilic urticarial pattern.
Journal of cutaneous pathology.
2017 Feb; 44(2):177-182. doi:
10.1111/cup.12863. [PMID: 27862184] - A A Lebedeva, N S Zakharchenko, E V Trubnikova, O A Medvedeva, T V Kuznetsova, G A Masgutova, M V Zylkova, Y I Buryanov, A S Belous. Bactericide, Immunomodulating, and Wound Healing Properties of Transgenic Kalanchoe pinnata Synergize with Antimicrobial Peptide Cecropin P1 In Vivo.
Journal of immunology research.
2017; 2017(?):4645701. doi:
10.1155/2017/4645701. [PMID: 28326334] - Sahajal Dhooria, Inderpaul Singh Sehgal, Kuruswamy Thurai Prasad, Amanjit Bal, Ashutosh Nath Aggarwal, Digambar Behera, Ritesh Agarwal. A Randomized Trial of Antimicrobial Prophylaxis in Patients Undergoing Medical Thoracoscopy (APT).
Respiration; international review of thoracic diseases.
2017; 94(2):207-215. doi:
10.1159/000477259. [PMID: 28624819] - Ryan Lillico, Casey L Sayre, Daniel S Sitar, Neal M Davies, Cynthia M Baron, Ted M Lakowski. Quantification of cefazolin in serum and adipose tissue by ultra high performance liquid chromatography-Tandem mass spectrometry (UHPLC-MS/MS): application to a pilot study of obese women undergoing cesarean delivery.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2016 Sep; 1031(?):94-98. doi:
10.1016/j.jchromb.2016.07.032. [PMID: 27469905] - M A Lantinga, T F M Wijnands, R H M Te Morsche, R G L de Sévaux, S Kuipers, K Allegaert, D Burger, J P H Drenth. Hepatic cyst penetration of cefazolin in patients receiving aspiration sclerotherapy.
The Journal of antimicrobial chemotherapy.
2016 09; 71(9):2547-52. doi:
10.1093/jac/dkw172. [PMID: 27246239] - Tiphaine Legrand, Dominique Vodovar, Nicolas Tournier, Nihel Khoudour, Anne Hulin. Simultaneous Determination of Eight β-Lactam Antibiotics, Amoxicillin, Cefazolin, Cefepime, Cefotaxime, Ceftazidime, Cloxacillin, Oxacillin, and Piperacillin, in Human Plasma by Using Ultra-High-Performance Liquid Chromatography with Ultraviolet Detection.
Antimicrobial agents and chemotherapy.
2016 08; 60(8):4734-42. doi:
10.1128/aac.00176-16. [PMID: 27216076] - Christian Lanckohr, Dagmar Horn, Swantje Voeller, Georg Hempel, Manfred Fobker, Henryk Welp, Robin Koeck, Bjoern Ellger. Pharmacokinetic characteristics and microbiologic appropriateness of cefazolin for perioperative antibiotic prophylaxis in elective cardiac surgery.
The Journal of thoracic and cardiovascular surgery.
2016 08; 152(2):603-10. doi:
10.1016/j.jtcvs.2016.04.024. [PMID: 27209020]