Phenoxybenzamine HCl (BioDeep_00000015085)
代谢物信息卡片
Phenoxybenzamine hydrochloride
化学式: C18H23Cl2NO (339.1157)
中文名称: 苯氧苄胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2.Cl
InChI: 1H
描述信息
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
Phenoxybenzamine hydrochloride is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine hydrochloride also shows antitumor activity[1][2].
同义名列表
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:8078
- KEGG: C07436
- KEGGdrug: D00507
- PubChem: 5284441
- ChEMBL: CHEMBL1200787
- MeSH: Phenoxybenzamine
- CAS: 34238-85-2
- CAS: 63-92-3
- PubChem: 9640
- medchemexpress: HY-B0431A
- KNApSAcK: 8078
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Marta Araujo-Castro, Rogelio García Centero, María-Carmen López-García, Cristina Álvarez Escolá, María Calatayud Gutiérrez, Concepción Blanco Carrera, Paz De Miguel Novoa, Nuria Valdés Gallego, Felicia A Hanzu, Paola Gracia Gimeno, Mariana Tomé Fernández-Ladreda, Juan Carlos Percovich Hualpa, Mireia Mora Porta, Javier Lorca Álvaro, Héctor Pian, Ignacio Ruz Caracuel, Alfonso Sanjuanbenito Dehesa, Victoria Gómez Dos Santos, Ana Serrano Romero, Cristina Lamas Oliveira. Surgical outcomes in the pheochromocytoma surgery. Results from the PHEO-RISK STUDY.
Endocrine.
2021 12; 74(3):676-684. doi:
10.1007/s12020-021-02843-6. [PMID: 34373995] - P Iglesias, E Santacruz, P García-Sancho, A P Marengo, F Guerrero-Pérez, H Pian, C Fajardo, C Villabona, J J Díez. Pheochromocytoma: A three-decade clinical experience in a multicenter study.
Revista clinica espanola.
2021 Jan; 221(1):18-25. doi:
10.1016/j.rceng.2019.12.011. [PMID: 33998473] - Linlin Fang, Yanyan Zhao, Chao Wang, Changyuan Wang, Xu Han, Pengjun Chen, Lizhu Zhao, Jingping Wang, Shuang Li, Zhen Jiang. Preparation of a thiols β-cyclodextrin/gold nanoparticles-coated open tubular column for capillary electrochromatography enantioseparations.
Journal of separation science.
2020 Jun; 43(11):2209-2216. doi:
10.1002/jssc.201901323. [PMID: 32160391] - Sungin Lee, Aeri Lee, Suh-Hyun Chai, Seulji Lee, Oh-Kyeong Kweon, Wan Hee Kim. Ectopic Cushing's syndrome associated with a pheochromocytoma in a dog: a case report.
BMC veterinary research.
2020 Feb; 16(1):35. doi:
10.1186/s12917-020-2244-7. [PMID: 32014021] - Ga-Won Lee, Cho-Rong Yoo, Dan Lee, Hee-Myung Park. Favorable outcome of pheochromocytoma in a dog with atypical Cushing's syndrome and diabetes mellitus following medical treatment: a case report.
BMC veterinary research.
2020 Jan; 16(1):3. doi:
10.1186/s12917-019-2225-x. [PMID: 31900158] - Lin Cao, Jizheng Chen, Yaxin Wang, Yuting Yang, Jie Qing, Zihe Rao, Xinwen Chen, Zhiyong Lou. Identification of serotonin 2A receptor as a novel HCV entry factor by a chemical biology strategy.
Protein & cell.
2019 03; 10(3):178-195. doi:
10.1007/s13238-018-0521-z. [PMID: 29542010] - Jie Tian, Zhengqing Bao, Yiming Yuan, Dong Fang, Yonghao Zhan, Tianyu Wang, Zheng Zhang, Zhou Liqun. The Duration of Preoperative Administration of Single α-Receptor Blocker Phenoxybenzamine before Adrenalectomy for Pheochromocytoma: 18 Years of Clinical Experience from Nationwide High-Volume Center.
BioMed research international.
2019; 2019(?):2613137. doi:
10.1155/2019/2613137. [PMID: 31828097] - Chengquan Ma, Erlin Sun, Bingxin Lu. Giant malignant pheochromocytoma in an elderly patient: A case report.
Medicine.
2018 May; 97(19):e0614. doi:
10.1097/md.0000000000010614. [PMID: 29742697] - James J Butz, Toby N Weingarten, Alexandre N Cavalcante, Irina Bancos, William F Young, Travis J McKenzie, Darrell R Schroeder, David P Martin, Juraj Sprung. Perioperative hemodynamics and outcomes of patients on metyrosine undergoing resection of pheochromocytoma or paraganglioma.
International journal of surgery (London, England).
2017 Oct; 46(?):1-6. doi:
10.1016/j.ijsu.2017.08.026. [PMID: 28803996] - Duncan Macrosson, Andrew Love. Perioperative management of a large, late presenting phaeochromocytoma.
BMJ case reports.
2017 Jan; 2017(?):. doi:
10.1136/bcr-2016-218126. [PMID: 28100576] - Ashwin Subramaniam, Robert Grauer, David Beilby, Ravindranath Tiruvoipati. Anesthetic management of a myotonic dystrophy patient with paraganglionoma.
Journal of clinical anesthesia.
2016 Nov; 34(?):21-8. doi:
10.1016/j.jclinane.2016.03.035. [PMID: 27687340] - Yu Omori, Mayumi Nakajima, Kazumi Nishimura, Eiki Takahashi, Tadamasa Arai, Masato Akahira, Tomohiko Suzuki, Mie Kainoh. Analgesic effect of GT-0198, a structurally novel glycine transporter 2 inhibitor, in a mouse model of neuropathic pain.
Journal of pharmacological sciences.
2015 Mar; 127(3):377-81. doi:
10.1016/j.jphs.2015.02.010. [PMID: 25837937] - L Cobret, M L De Tauzia, J Ferent, E Traiffort, I Hénaoui, F Godin, E Kellenberger, D Rognan, J Pantel, H Bénédetti, S Morisset-Lopez. Targeting the cis-dimerization of LINGO-1 with low MW compounds affects its downstream signalling.
British journal of pharmacology.
2015 Feb; 172(3):841-56. doi:
10.1111/bph.12945. [PMID: 25257685] - Dolores Ollero García-Agulló, Ana Iriarte Beroiz, Jorge Rojo Alvaro, Patricia Munárriz, Lluis Forga Llenas. [Familial pheochromocytoma associated to neurofibromatosis type 1].
Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion.
2013 Aug; 60(7):421-2. doi:
10.1016/j.endonu.2012.08.004. [PMID: 23182535] - Hasan K Siddiqi, Hui-yu Yang, Amanda M Laird, Amy C Fox, Gerard M Doherty, Barbra S Miller, Paul G Gauger. Utility of oral nicardipine and magnesium sulfate infusion during preparation and resection of pheochromocytomas.
Surgery.
2012 Dec; 152(6):1027-36. doi:
10.1016/j.surg.2012.08.023. [PMID: 23158177] - Harvinder Singh Pahwa, Awanish Kumar, Rohit Srivastava, Anurag Rai. Unsuspected pheochromocytoma of the urinary bladder: reminder of an important clinical lesson.
BMJ case reports.
2012 Aug; 2012(?):. doi:
10.1136/bcr-2012-006377. [PMID: 22878991] - James C Sisson, Thomas J Giordano, Anca M Avram. Three endocrine neoplasms: an unusual combination of pheochromocytoma, pituitary adenoma, and papillary thyroid carcinoma.
Thyroid : official journal of the American Thyroid Association.
2012 Apr; 22(4):430-6. doi:
10.1089/thy.2011.0345. [PMID: 22385288] - A J Akindele, O Awodele, A A Alagbaoso, O O Adeyemi. Antidiarrhoeal activity of DAS-77 (a herbal preparation).
Nigerian quarterly journal of hospital medicine.
2011 Oct; 21(4):317-23. doi:
". [PMID: 23175899] - Inmaculada Navarro, Mercedes Molina, Miguel Civera, Juan F Ascaso, José T Real, Rafael Carmena. [Catecholamine-induced cardiomyopathy triggered by pheochromocytoma].
Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion.
2011 Apr; 58(4):204-6. doi:
10.1016/j.endonu.2010.11.005. [PMID: 21393076] - Brian T Welch, Thomas D Atwell, Douglas A Nichols, C Thomas Wass, Matthew R Callstrom, Bradley C Leibovich, Paul C Carpenter, Jayawant N Mandrekar, J William Charboneau. Percutaneous image-guided adrenal cryoablation: procedural considerations and technical success.
Radiology.
2011 Jan; 258(1):301-7. doi:
10.1148/radiol.10100631. [PMID: 20971772] - Elif Cadirci, Halis Suleyman, Ahmet Hacimuftuoglu, Zekai Halici, Fatih Akcay. Indirect role of beta2-adrenergic receptors in the mechanism of analgesic action of nonsteroidal antiinflammatory drugs.
Critical care medicine.
2010 Sep; 38(9):1860-7. doi:
10.1097/ccm.0b013e3181e8ae24. [PMID: 20601862] - Joyce S Y Yau, June K Y Li, Vicki H K Tam, L M Fung, C K Yeung, K W Chan, K M Lee, K F Lee, W S Cheung, Vincent T F Yeung, Y P Yuen, W K Kwan. Phaeochromocytoma in the Hong Kong Chinese population.
Hong Kong medical journal = Xianggang yi xue za zhi.
2010 Aug; 16(4):252-6. doi:
NULL. [PMID: 20683066] - H Bruynzeel, R A Feelders, T H N Groenland, A H van den Meiracker, C H J van Eijck, J F Lange, W W de Herder, G Kazemier. Risk Factors for Hemodynamic Instability during Surgery for Pheochromocytoma.
The Journal of clinical endocrinology and metabolism.
2010 Feb; 95(2):678-85. doi:
10.1210/jc.2009-1051. [PMID: 19965926] - Sanjay Kasturi, Alexander Kutikov, Thomas J Guzzo, Ariana L Smith, Alan J Wein. Modern management of pheochromocytoma.
Nature clinical practice. Urology.
2007 Nov; 4(11):630-3. doi:
10.1038/ncpuro0962. [PMID: 17982440] - S-D Chung, K-H Huang, C-H Liao, H-C Tai, H-J Yu, S-C Chueh. Acute heart failure with elevated cardiac enzymes.
Kidney international.
2007 Aug; 72(4):521-3. doi:
10.1038/sj.ki.5002290. [PMID: 17687383] - Kerstin Amann, Jürgen Hofstetter, Valentina Câmpean, Andreas Koch, Marie-Luise Gross, Roland Veelken, Eberhard Ritz. Nonhypotensive dose of beta-adrenergic blocker ameliorates capillary deficits in the hearts of rats with moderate renal failure.
Virchows Archiv : an international journal of pathology.
2006 Aug; 449(2):207-14. doi:
10.1007/s00428-006-0219-0. [PMID: 16691425] - Ho-Jin Kang, Sang-Seop Lee, Chung-Hee Lee, Ju-Cheol Shim, Ho Jung Shin, Kwang-Hyeon Liu, Mi-Ae Yoo, Jae-Gook Shin. Neurotoxic pyridinium metabolites of haloperidol are substrates of human organic cation transporters.
Drug metabolism and disposition: the biological fate of chemicals.
2006 Jul; 34(7):1145-51. doi:
10.1124/dmd.105.009126. [PMID: 16624869] - Christine Kulstad, Jason D'Amore. Clinicopathological conference: a 42-year-old woman with respiratory distress, abdominal pain, and hypertension.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.
2005 May; 12(5):453-60. doi:
10.1197/j.aem.2004.09.024. [PMID: 15860698] - Jun Li, Barbara A French, Paul Fu, Fawzia Bardag-Gorce, Samuel W French. Catecholamines are involved in the mechanism of the urinary alcohol level cycle in rats fed ethanol intragastrically at a constant rate.
Life sciences.
2004 Nov; 75(25):3043-51. doi:
10.1016/j.lfs.2004.05.032. [PMID: 15474556] - L D Sabath, Germaine Cornélissen, Franz Halberg, Alexander Stoynev, Ognian Ikonomov, Kuniaki Otsuka. Circadian hypo- and hyper-amplitude-tension (CHAT) associated with putative pheochromocytoma and 12-hourly phenoxybenzamine treatment.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2004 Oct; 58 Suppl 1(?):S99-106. doi:
10.1016/s0753-3322(04)80016-7. [PMID: 15754846] - Dong-liang Pan, Han-zhong Li, Zheng-pei Zeng. [The discussion of standards for clinical functional gradation and preoperative preparation of pheochromocytoma].
Zhonghua wai ke za zhi [Chinese journal of surgery].
2004 Sep; 42(18):1089-92. doi:
. [PMID: 15498292] - J A Hasrat, L Pieters, A J Vlietinck. Medicinal plants in Suriname: hypotensive effect of Gossypium barbadense.
The Journal of pharmacy and pharmacology.
2004 Mar; 56(3):381-7. doi:
10.1211/0022357022917. [PMID: 15025864] - Duane J Myklejord. Undiagnosed pheochromocytoma: the anesthesiologist nightmare.
Clinical medicine & research.
2004 Feb; 2(1):59-62. doi:
10.3121/cmr.2.1.59. [PMID: 15931336] - Kathleen Brown, Michael Ratner, Mathew Stoll. Pheochromocytoma unmasked by imipramine in an 8-year-old girl.
Pediatric emergency care.
2003 Jun; 19(3):174-7. doi:
10.1097/01.pec.0000081243.98249.e9. [PMID: 12813305] - Graeme Eisenhofer, David S Goldstein, McClellan M Walther, Peter Friberg, Jacques W M Lenders, Harry R Keiser, Karel Pacak. Biochemical diagnosis of pheochromocytoma: how to distinguish true- from false-positive test results.
The Journal of clinical endocrinology and metabolism.
2003 Jun; 88(6):2656-66. doi:
10.1210/jc.2002-030005. [PMID: 12788870] - O Tarasova, N Sjöblom-Widfeldt, H Nilsson. Transmitter characteristics of cutaneous, renal and skeletal muscle small arteries in the rat.
Acta physiologica Scandinavica.
2003 Feb; 177(2):157-66. doi:
10.1046/j.1365-201x.2003.01057.x. [PMID: 12558552] - Savas Kocak, Semih Aydintug, Necati Canakci. Alpha blockade in preoperative preparation of patients with pheochromocytomas.
International surgery.
2002 Jul; 87(3):191-4. doi:
NULL. [PMID: 12403097] - J Damas, C Hallet, P J Lefebvre. Changes in blood glucose and plasma insulin levels induced by bradykinin in anaesthetized rats.
British journal of pharmacology.
2001 Nov; 134(6):1312-8. doi:
10.1038/sj.bjp.0704374. [PMID: 11704652] - F D McCarter, J H James, F A Luchette, L Wang, L A Friend, J K King, J M Evans, M A George, J E Fischer. Adrenergic blockade reduces skeletal muscle glycolysis and Na(+), K(+)-ATPase activity during hemorrhage.
The Journal of surgical research.
2001 Aug; 99(2):235-44. doi:
10.1006/jsre.2001.6175. [PMID: 11469892] - S Tsakiris. Effects of L-phenylalanine on acetylcholinesterase and Na(+), K(+)-ATPase activities in adult and aged rat brain.
Mechanisms of ageing and development.
2001 Apr; 122(5):491-501. doi:
10.1016/s0047-6374(01)00217-2. [PMID: 11292514] - S Hayami, M Yaita, Y Ogiri, F Sun, R Nakata, S Kojo. Change in caspase-3-like protease in the liver and plasma during rat liver regeneration following partial hepatectomy.
Biochemical pharmacology.
2000 Dec; 60(12):1883-6. doi:
10.1016/s0006-2952(00)00508-6. [PMID: 11108804] - J V Joseph, R Harrison, R S Davis. Multiple endocrine neoplasia type IIA (Sipple's syndrome) presenting in pregnancy.
The Australian & New Zealand journal of obstetrics & gynaecology.
2000 Nov; 40(4):473-4. doi:
10.1111/j.1479-828x.2000.tb01188.x. [PMID: 11194443] - A Honaramooz, R K Chandolia, A P Beard, N C Rawlings. Opioidergic, dopaminergic and adrenergic regulation of LH secretion in prepubertal heifers.
Journal of reproduction and fertility.
2000 Jul; 119(2):207-15. doi:
. [PMID: 10864832] - J S Greiwe, J O Holloszy, C F Semenkovich. Exercise induces lipoprotein lipase and GLUT-4 protein in muscle independent of adrenergic-receptor signaling.
Journal of applied physiology (Bethesda, Md. : 1985).
2000 Jul; 89(1):176-81. doi:
10.1152/jappl.2000.89.1.176. [PMID: 10904050] - R E Eckert, A J Karsten, J Utz, M Ziegler. Regulation of renal artery smooth muscle tone by alpha1-adrenoceptors: role of voltage-gated calcium channels and intracellular calcium stores.
Urological research.
2000 Apr; 28(2):122-7. doi:
10.1007/s002400050149. [PMID: 10850635] - M Al-Ali, G Salman, A Rasheed, G Al-Ani, S Al-Rubaiy, A Alwan, A Al-Shaikli. Phenoxybenzamine in the management of neuropathic bladder following spinal cord injury.
The Australian and New Zealand journal of surgery.
1999 Sep; 69(9):660-3. doi:
10.1046/j.1440-1622.1999.01659.x. [PMID: 10515340] - M C Lebeau, I Jung-Testas, E E Baulieu. Intracellular distribution of a cytoplasmic progesterone receptor mutant and of immunophilins cyclophilin 40 and FKBP59: effects of cyclosporin A, of various metabolic inhibitors and of several culture conditions.
The Journal of steroid biochemistry and molecular biology.
1999 Sep; 70(4-6):219-28. doi:
10.1016/s0960-0760(99)00118-1. [PMID: 10622411] - F A Luchette, B R Robinson, L A Friend, F McCarter, S B Frame, J H James. Adrenergic antagonists reduce lactic acidosis in response to hemorrhagic shock.
The Journal of trauma.
1999 May; 46(5):873-80. doi:
10.1097/00005373-199905000-00017. [PMID: 10338406] - H Tsushima, M Mori. Central injections of capsaicin cause antidiuresis mediated through neurokinin-1 receptors in rat hypothalamus and vasopressin release.
Japanese journal of pharmacology.
1999 Feb; 79(2):237-41. doi:
10.1254/jjp.79.237. [PMID: 10202860] - N J Bernier, S F Perry. Cardiovascular effects of angiotensin-II-mediated adrenaline release in rainbow trout Oncorhynchus mykiss.
The Journal of experimental biology.
1999 Jan; 202(Pt 1):55-66. doi:
10.1242/jeb.202.1.55. [PMID: 9841895] - S C Lee, Y H Lee. Calcium/calmodulin-dependent signaling for appressorium formation in the plant pathogenic fungus Magnaporthe grisea.
Molecules and cells.
1998 Dec; 8(6):698-704. doi:
". [PMID: 9895122] - B P Kennedy, S K Mahata, D T O'Connor, M G Ziegler. Mechanism of cardiovascular actions of the chromogranin A fragment catestatin in vivo.
Peptides.
1998; 19(7):1241-8. doi:
10.1016/s0196-9781(98)00086-2. [PMID: 9786174] - H C Kuo. Comparative study of therapeutic effect of dibenyline, finasteride, and combination drugs for symptomatic benign prostatic hyperplasia.
Urologia internationalis.
1998; 60(2):85-91. doi:
10.1159/000030217. [PMID: 9563145] - H Tsushima, M Mori, T Matsuda. Central regulation of urine production by a selective mu-opioid agonist, [D-Ala2, N-Me-Phe4, Gly5-ol]-enkephalin, in rats.
Japanese journal of pharmacology.
1997 May; 74(1):45-9. doi:
10.1254/jjp.74.45. [PMID: 9195296] - B Kennedy, G H Shen, M G Ziegler. Neuropeptide Y-mediated pressor responses following high-frequency stimulation of the rat sympathetic nervous system.
The Journal of pharmacology and experimental therapeutics.
1997 Apr; 281(1):291-6. doi:
NULL. [PMID: 9103509] - J J Mukherjee, P D Peppercorn, R H Reznek, V Patel, G Kaltsas, M Besser, A B Grossman. Pheochromocytoma: effect of nonionic contrast medium in CT on circulating catecholamine levels.
Radiology.
1997 Jan; 202(1):227-31. doi:
10.1148/radiology.202.1.8988215. [PMID: 8988215] - G Förster, G Schulz, G Kahaly. [Premedication in pheochromocytoma].
Zentralblatt fur Chirurgie.
1997; 122(6):454-9. doi:
NULL. [PMID: 9334112] - E Sehic, Y Ruan, K U Malik. Mechanism of resistance to alpha-adrenergic receptor antagonists of renal nerve stimulation-induced vasoconstriction at low frequencies.
Journal of cardiovascular pharmacology.
1997 Jan; 29(1):97-108. doi:
10.1097/00005344-199701000-00016. [PMID: 9007678] - R E Malmström, J M Lundberg. Effects of the neuropeptide YY1 receptor antagonist SR 120107A on sympathetic vascular control in pigs in vivo.
Naunyn-Schmiedeberg's archives of pharmacology.
1996 Nov; 354(5):633-42. doi:
10.1007/bf00170839. [PMID: 8938663] - M L Santeiro, C Stromquist, L Wyble. Phenoxybenzamine placental transfer during the third trimester.
The Annals of pharmacotherapy.
1996 Nov; 30(11):1249-51. doi:
10.1177/106002809603001108. [PMID: 8913406] - B Dabrowska, P Pruszczyk, A Dabrowski, T Feltynowski, B Wocial, W Januszewicz. Influence of alpha-adrenergic blockade on ventricular arrhythmias, QTc interval and heart rate variability in phaeochromocytoma.
Journal of human hypertension.
1995 Nov; 9(11):925-9. doi:
NULL. [PMID: 8583473] - J F Monkelbaan, H A Cats, C H Beerenhout, R P Dullaart, T W van Haeften. Phaeochromocytoma in various disguises.
The Netherlands journal of medicine.
1995 Aug; 47(2):70-5. doi:
10.1016/0300-2977(94)00110-u. [PMID: 7566285] - A Kumar, G K Banerjee, M C Goel, V K Mishra, R Kapoor, M Bhandari. Functional bladder neck obstruction: a rare cause of renal failure.
The Journal of urology.
1995 Jul; 154(1):186-9. doi:
10.1016/s0022-5347(01)67262-8. [PMID: 7776419] - M Yasin, A C Dalkin, D J Haisenleder, J R Kerrigan, J C Marshall. Gonadotropin-releasing hormone (GnRH) pulse pattern regulates GnRH receptor gene expression: augmentation by estradiol.
Endocrinology.
1995 Apr; 136(4):1559-64. doi:
10.1210/endo.136.4.7895666. [PMID: 7895666] - I Browne, G Thomas, K Gavin, J R Docherty. Prejunctional actions of N-ethyl-maleimide and phenoxybenzamine in rat vas deferens.
European journal of pharmacology.
1994 Nov; 265(3):125-32. doi:
10.1016/0014-2999(94)90422-7. [PMID: 7875227] - K P Minneman, T L Theroux, S Hollinger, C Han, T A Esbenshade. Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes.
Molecular pharmacology.
1994 Nov; 46(5):929-36. doi:
. [PMID: 7969082] - H Tsushima, M Mori, T Matsuda. Microinjections of angiotensin II into the supraoptic and paraventricular nuclei produce potent antidiureses by vasopressin release mediated through adrenergic and angiotensin receptors.
Japanese journal of pharmacology.
1994 Oct; 66(2):241-6. doi:
10.1254/jjp.66.241. [PMID: 7869608] - T Kuo, Y Ouchi, S Kim, K Toba, H Orimo. The role of activation of the sympathetic nervous system in the central pressor action of calcitonin gene-related peptide in conscious rats.
Naunyn-Schmiedeberg's archives of pharmacology.
1994 Apr; 349(4):394-400. doi:
10.1007/bf00170886. [PMID: 8058111] - J R Kerrigan, A C Dalkin, D J Haisenleder, M Yasin, J C Marshall. Failure of gonadotropin-releasing hormone (GnRH) pulses to increase luteinizing hormone beta messenger ribonucleic acid in GnRH-deficient female rats.
Endocrinology.
1993 Nov; 133(5):2071-9. doi:
10.1210/endo.133.5.8404655. [PMID: 8404655] - N P Kerezoudis, L Olgart, L Edwall. Evans blue extravasation in rat dental pulp and oral tissues induced by electrical stimulation of the inferior alveolar nerve.
Archives of oral biology.
1993 Oct; 38(10):893-901. doi:
10.1016/0003-9969(93)90099-8. [PMID: 8279994] - N P Kerezoudis, L Olgart, A Funato, L Edwall. Inhibitory influence of sympathetic nerves on afferent nerve-induced extravasation in the rat incisor pulp upon direct electrical stimulation of the tooth.
Archives of oral biology.
1993 Jun; 38(6):483-90. doi:
10.1016/0003-9969(93)90184-n. [PMID: 8393653] - Z Sarnyai, E Bíró, G Telegdy. Cocaine-induced elevation of plasma corticosterone is mediated by different neurotransmitter systems in rats.
Pharmacology, biochemistry, and behavior.
1993 May; 45(1):209-14. doi:
10.1016/0091-3057(93)90106-4. [PMID: 8100073] - J H Schwieler, T Kahan, J Nussberger, P Hjemdahl. Converting enzyme inhibition modulates sympathetic neurotransmission in vivo via multiple mechanisms.
The American journal of physiology.
1993 Apr; 264(4 Pt 1):E631-7. doi:
10.1152/ajpendo.1993.264.4.e631. [PMID: 8386457] - J H Schwieler, P Hjemdahl. D-myo-inositol-1,2,6-triphosphate (PP56) antagonizes nonadrenergic sympathetic vasoconstriction: possible involvement of neuropeptide Y.
Journal of cardiovascular pharmacology.
1993 Mar; 21(3):347-52. doi:
10.1097/00005344-199303000-00001. [PMID: 7681493] - C Bohmann, P Schollmeyer, L C Rump. Alpha 2-autoreceptor subclassification in rat isolated kidney by use of short trains of electrical stimulation.
British journal of pharmacology.
1993 Jan; 108(1):262-8. doi:
10.1111/j.1476-5381.1993.tb13472.x. [PMID: 8094025] - H Y Xu, K R Olson. Evidence for multiple adrenoceptor sites in rainbow trout vasculature.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology.
1993; 163(6):470-6. doi:
10.1007/bf00346931. [PMID: 8071465] - J Pizarro, M M Warner, M Ryan, G S Mitchell, G E Bisgard. Intracarotid norepinephrine infusions inhibit ventilation in goats.
Respiration physiology.
1992 Dec; 90(3):299-310. doi:
10.1016/0034-5687(92)90110-i. [PMID: 1480841] - J L Hall, P E Gold. Plasma glucose levels predict the disrupting effects of adrenoceptor antagonists on enhancement of memory storage.
European journal of pharmacology.
1992 Oct; 221(2-3):365-70. doi:
10.1016/0014-2999(92)90724-i. [PMID: 1426012] - F Mármol, L Carbonell, M L Cuffí, J Forn. Demonstration of inhibition of cyclic AMP accumulation in brain by very low concentrations of lithium in the presence of alpha-adrenoceptor blockade.
European journal of pharmacology.
1992 May; 226(1):93-6. doi:
10.1016/0922-4106(92)90087-c. [PMID: 1356811] - J Breuer, J Föll, H Renz-Polster, H Rebmann, W Rosendahl, D Wilbert. [Hinman syndrome. Pronounced renal failure as a sequela of pseudo-neurogenic disorder of bladder emptying].
Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde.
1992 Mar; 140(3):162-5. doi:
NULL. [PMID: 1603099] - T Wells, M L Forsling. Aminergic control of vasopressin secretion in the conscious rat.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
1992 Mar; 43(1):59-64. doi:
NULL. [PMID: 1450434] - D Zheng, H S Chen, D Y Hu. Cardiovascular mechanisms of thyrotropin-releasing hormone against experimental hemorrhagic shock.
Circulatory shock.
1992 Mar; 36(3):169-73. doi:
. [PMID: 1611701] - X R Xiao. [Diagnosis and treatment of pheochromocytoma. Report of 48 cases].
Zhonghua wai ke za zhi [Chinese journal of surgery].
1992 Mar; 30(3):159-62, 189. doi:
NULL. [PMID: 1473388] - M W Rooney, L J Hirsch. Skeletal muscle blood flow and O2 uptake during intravenous nicotine with and without hypertension.
Journal of cardiovascular pharmacology.
1991 Oct; 18(4):535-41. doi:
10.1097/00005344-199110000-00009. [PMID: 1724530] - K Yamaguchi, H Hama. Separation of periventricular dopaminergic and alpha-adrenergic systems from the vasopressin-secreting mechanisms activated by prostaglandin D2.
Brain research.
1991 Sep; 559(2):261-6. doi:
10.1016/0006-8993(91)90010-s. [PMID: 1665382] - J H Johnson, C S Kitts. Analysis of neurotransmitter receptors mediating changes in LH release induced by electrical stimulation of the dorsal raphe nucleus in the rat.
Journal of neuroscience research.
1991 Aug; 29(4):520-6. doi:
10.1002/jnr.490290412. [PMID: 1665188] - M L Blair, H Hisa, C D Sladek, K J Radke, F M Gengo. Dual adrenergic control of renin during nonhypotensive hemorrhage in conscious dogs.
The American journal of physiology.
1991 Jun; 260(6 Pt 1):E910-9. doi:
10.1152/ajpendo.1991.260.6.e910. [PMID: 1647672] - E Grossman, D S Goldstein, A Hoffman, H R Keiser. Glucagon and clonidine testing in the diagnosis of pheochromocytoma.
Hypertension (Dallas, Tex. : 1979).
1991 Jun; 17(6 Pt 1):733-41. doi:
10.1161/01.hyp.17.6.733. [PMID: 2045133] - G J Crystal. Hemodynamic effects of nicotine in canine skeletal muscle.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1991 Apr; 196(4):421-7. doi:
10.3181/00379727-196-43210. [PMID: 1672564] - K R Purushotham, T Zelles, M G Humphreys-Beher. Role of protein phosphorylation and inositol phospholipid turnover in rat parotid gland proliferation.
Molecular and cellular biochemistry.
1991 Mar; 102(1):19-33. doi:
10.1007/bf00232155. [PMID: 1904983] - C H Vanderwolf, R K Cooley. Phenoxybenzamine reduces mortality associated with intracerebral injections of excitatory neurotoxins.
Pharmacology, biochemistry, and behavior.
1991 Mar; 38(3):689-90. doi:
10.1016/0091-3057(91)90036-2. [PMID: 2068208] - R Y Man, W M Hu, T Mock, A A Kinnaird. Effects of palmitoyl carnitine and structural analogs on arterial blood pressure in the rat. A comparison with platelet-activating factor.
Journal of lipid mediators.
1991 Mar; 3(2):205-14. doi:
NULL. [PMID: 1686730] - A J Krentz, P J Hale, P M Horrocks, K E Heslop, D G Johnston, A D Wright, M Nattrass. Metabolic effects of pharmacological adrenergic blockade in phaeochromocytoma.
Clinical endocrinology.
1991 Feb; 34(2):139-45. doi:
10.1111/j.1365-2265.1991.tb00284.x. [PMID: 2022064] - R R Perry, H R Keiser, J A Norton, R T Wall, C N Robertson, W Travis, H I Pass, M M Walther, W M Linehan. Surgical management of pheochromocytoma with the use of metyrosine.
Annals of surgery.
1990 Nov; 212(5):621-8. doi:
10.1097/00000658-199011000-00010. [PMID: 1978640] - C Morimoto, T Tsujita, H Okuda. Propranolol-sensitive and phenoxybenzamine-insensitive binding of norepinephrine to endogenous lipid droplets from rat adipocytes.
Biochemical medicine and metabolic biology.
1990 Oct; 44(2):126-34. doi:
10.1016/0885-4505(90)90053-4. [PMID: 2252613] - K M Wilson, S Gilchrist, K P Minneman. Comparison of alpha 1-adrenergic receptor-stimulated inositol phosphate formation in primary neuronal and glial cultures.
Journal of neurochemistry.
1990 Aug; 55(2):691-7. doi:
10.1111/j.1471-4159.1990.tb04188.x. [PMID: 1973457] - C Grunfeld, S Adi, M Soued, A Moser, W Fiers, K R Feingold. Search for mediators of the lipogenic effects of tumor necrosis factor: potential role for interleukin 6.
Cancer research.
1990 Jul; 50(14):4233-8. doi:
NULL. [PMID: 2364381] - S Gullapalli, C K Kurup, T Ramasarma. Decavanadate acts like an alpha-adrenergic agonist in redistributing protein kinase C activity.
FEBS letters.
1990 Jul; 267(1):93-5. doi:
10.1016/0014-5793(90)80296-u. [PMID: 1973125] - H Grosse, D Schröder, O Schober, B Hausen, H Dralle. [The importance of high-dose alpha-receptor blockade for blood volume and hemodynamics in pheochromocytoma].
Der Anaesthesist.
1990 Jun; 39(6):313-8. doi:
NULL. [PMID: 1973879]
