Diethylcarbamazine Citrate (BioDeep_00000015084)

   


代谢物信息卡片


Diethylcarbamazine Citrate

化学式: C16H29N3O8 (391.1954554)
中文名称: 枸橼酸乙胺嗪
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCN(CC)C(=O)N1CCN(CC1)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
InChI: 13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

描述信息

D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics
C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent
D004791 - Enzyme Inhibitors > D016859 - Lipoxygenase Inhibitors

同义名列表

1 个代谢物同义名

Diethylcarbamazine Citrate



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Kiran Agarwal, Kavita Gaur, Nazma Khasim. Filariasis presenting with bicytopenia, progressive splenomegaly and acute renal failure: An unusual case report. Tropical doctor. 2021 Oct; 51(4):588-590. doi: 10.1177/00494755211002027. [PMID: 33977778]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Anuruddha Abeygunasekera, Saroj Jayasinghe. Is the anti-filarial drug diethylcarbamazine useful to treat COVID-19?. Medical hypotheses. 2020 Oct; 143(?):109843. doi: 10.1016/j.mehy.2020.109843. [PMID: 32492560]
  • Nosibah Abdul-Razek, Al-Mahy M El-Mallah, Abdelaziz S A Abuelsaad, Mahmoud Abdel-Latif. Enhancement of Anti-allergic Effect of Diethylcarbamazine Citrate in Asthmatic Mouse Model: Testing of Anti-drug Antibodies and Quercetin. Iranian journal of allergy, asthma, and immunology. 2020 Aug; 19(4):373-385. doi: 10.18502/ijaai.v19i4.4112. [PMID: 33463104]
  • Andi Dian Permana, Ismaiel A Tekko, Maelíosa T C McCrudden, Qonita Kurnia Anjani, Delly Ramadon, Helen O McCarthy, Ryan F Donnelly. Solid lipid nanoparticle-based dissolving microneedles: A promising intradermal lymph targeting drug delivery system with potential for enhanced treatment of lymphatic filariasis. Journal of controlled release : official journal of the Controlled Release Society. 2019 12; 316(?):34-52. doi: 10.1016/j.jconrel.2019.10.004. [PMID: 31655132]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Britt J Andersen, Bruce A Rosa, Jonah Kupritz, Aboulaye Meite, Traye Serge, Marla I Hertz, Kurt Curtis, Christopher L King, Makedonka Mitreva, Peter U Fischer, Gary J Weil. Systems analysis-based assessment of post-treatment adverse events in lymphatic filariasis. PLoS neglected tropical diseases. 2019 09; 13(9):e0007697. doi: 10.1371/journal.pntd.0007697. [PMID: 31557154]
  • Andi Dian Permana, Ismaiel A Tekko, Helen O McCarthy, Ryan F Donnelly. New HPLC-MS method for rapid and simultaneous quantification of doxycycline, diethylcarbamazine and albendazole metabolites in rat plasma and organs after concomitant oral administration. Journal of pharmaceutical and biomedical analysis. 2019 Jun; 170(?):243-253. doi: 10.1016/j.jpba.2019.03.047. [PMID: 30947125]
  • Gabriel Barros Rodrigues, Elquio Eleamen Oliveira, Francisco Jaime Bezerra Mendonça Junior, Laise Aline Martins Dos Santos, Wilma Helena de Oliveira, Maria Eduarda Rocha de França, Deniele Bezerra Lós, Brennda Martins Gabínio, Christina Alves Peixoto. A new diethylcarbamazine formulation (NANO-DEC) as a therapeutic tool for hepatic fibrosis. International immunopharmacology. 2018 Nov; 64(?):280-288. doi: 10.1016/j.intimp.2018.09.010. [PMID: 30219503]
  • Yashpal S Chhonker, Constant Edi, Daryl J Murry. LC-MS/MS method for simultaneous determination of diethylcarbamazine, albendazole and albendazole metabolites in human plasma: Application to a clinical pharmacokinetic study. Journal of pharmaceutical and biomedical analysis. 2018 Mar; 151(?):84-90. doi: 10.1016/j.jpba.2017.12.037. [PMID: 29310051]
  • Gaurav Garg, Apul Goel, Sunny Goel, Manmeet Singh. Chyluria in young child: a rare presentation. BMJ case reports. 2018 Mar; 2018(?):. doi: 10.1136/bcr-2017-223516. [PMID: 29549133]
  • Gabriel Barros Rodrigues, Elquio Eleamen Oliveira, Francisco Jaime Bezerra Mendonça Junior, Laise Aline Martins Dos Santos, Wilma Helena de Oliveira, Maria Eduarda Rocha de França, Deniele Bezerra Lós, Brennda Martins Gabínio, Fábia Cristiane Melo Leite de Lira, Christina Alves Peixoto. Characterization and evaluation of nanoencapsulated diethylcarbamazine in model of acute hepatic inflammation. International immunopharmacology. 2017 Sep; 50(?):330-337. doi: 10.1016/j.intimp.2017.07.014. [PMID: 28743082]
  • Anuruddha M Abeygunasekera, Kugadas Sutharshan, Balasingam Balagobi. New developments in chyluria after global programs to eliminate lymphatic filariasis. International journal of urology : official journal of the Japanese Urological Association. 2017 08; 24(8):582-588. doi: 10.1111/iju.13378. [PMID: 28556416]
  • Alaa El-Din El-Sayed El-Sisi, Samia Salim Sokar, Abdelhadi Mohamed Shebl, Dina Zakaria Mohamed. Antifibrotic effect of diethylcarbamazine combined with hesperidin against ethanol induced liver fibrosis in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2017 May; 89(?):1196-1206. doi: 10.1016/j.biopha.2017.03.013. [PMID: 28320086]
  • Jesica A Herrick, Fanny Legrand, Raceline Gounoue, Godwin Nchinda, Céline Montavon, Jean Bopda, Steve Mbickmen Tchana, Bienvenu Etogo Ondigui, Konrad Nguluwe, Michael P Fay, Michelle Makiya, Simon Metenou, Thomas B Nutman, Joseph Kamgno, Amy D Klion. Posttreatment Reactions After Single-Dose Diethylcarbamazine or Ivermectin in Subjects With Loa loa Infection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2017 04; 64(8):1017-1025. doi: 10.1093/cid/cix016. [PMID: 28329346]
  • Vikas Kushwaha, Kirti Saxena, Richa Verma, Shiv K Verma, Deepali Katoch, Neeraj Kumar, Brij Lal, P Kalpana Murthy, Bikram Singh. Antifilarial activity of diterpenoids from Taxodium distichum. Parasites & vectors. 2016 05; 9(1):312. doi: 10.1186/s13071-016-1592-4. [PMID: 27245322]
  • Saurabh Kumar, Rajbeer Singh Beri. A rare presentation of hydropneumothorax in tropical pulmonary eosinophilia: cavitation and pneumonic consolidation in a child. Tropical doctor. 2016 Apr; 46(2):105-8. doi: 10.1177/0049475515606011. [PMID: 26376823]
  • Praveen Kumar Tripathi, Ramesh Chander Mahajan, Nancy Malla, Abhishek Mewara, Shailja Misra Bhattacharya, Ranganatha Krishna Shenoy, Rakesh Sehgal. Circulating filarial antigen detection in brugian filariasis. Parasitology. 2016 Mar; 143(3):350-7. doi: 10.1017/s0031182015001675. [PMID: 26646772]
  • Johnny Vlaminck, Taniawati Supali, Peter Geldhof, Cornelis H Hokke, Peter U Fischer, Gary J Weil. Community Rates of IgG4 Antibodies to Ascaris Haemoglobin Reflect Changes in Community Egg Loads Following Mass Drug Administration. PLoS neglected tropical diseases. 2016 Mar; 10(3):e0004532. doi: 10.1371/journal.pntd.0004532. [PMID: 26991326]
  • Edward K Thomsen, Nelly Sanuku, Manasseh Baea, Samson Satofan, Elit Maki, Bart Lombore, Mark S Schmidt, Peter M Siba, Gary J Weil, James W Kazura, Lawrence L Fleckenstein, Christopher L King. Efficacy, Safety, and Pharmacokinetics of Coadministered Diethylcarbamazine, Albendazole, and Ivermectin for Treatment of Bancroftian Filariasis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2016 Feb; 62(3):334-341. doi: 10.1093/cid/civ882. [PMID: 26486704]
  • Arjang Talattof, Judy C Price, Gordon L Amidon. Gastrointestinal Motility Variation and Implications for Plasma Level Variation: Oral Drug Products. Molecular pharmaceutics. 2016 Feb; 13(2):557-67. doi: 10.1021/acs.molpharmaceut.5b00774. [PMID: 26692042]
  • Mahmoud Abdel-Latif. Diethylcarbamazine citrate ameliorates insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation. International immunopharmacology. 2015 Dec; 29(2):607-612. doi: 10.1016/j.intimp.2015.09.021. [PMID: 26432178]
  • Mahmoud Abdel-Latif, Thabet Sakran, Gamal El-Shahawi, Hoda El-Fayoumi, Al-Mahy El-Mallah. Immunomodulatory effect of diethylcarbamazine citrate plus filarial excretory-secretory product on rat hepatocarcinogenesis. International immunopharmacology. 2015 Feb; 24(2):173-181. doi: 10.1016/j.intimp.2014.12.004. [PMID: 25499729]
  • Mahmoud Abdel-Latif, Thabet Sakran, Gamal El-Shahawi, Hoda El-Fayoumi, Al-Mahy El-Mallah. Effect of diethylcarbamazine citrate and Setaria equina excretory-secretory material on rat hepatocellular carcinoma. Archivum immunologiae et therapiae experimentalis. 2014 Dec; 62(6):511-20. doi: 10.1007/s00005-014-0292-z. [PMID: 24879096]
  • Karthik Siram, Vijaya Raghavan Chellan, Tamilselvan Natarajan, Balakumar Krishnamoorthy, Habibur Rahman Mohamed Ebrahim, Vamshikrishna Karanam, Siva Selva Kumar Muthuswamy, Hari Prasad Ranganathan. Solid lipid nanoparticles of diethylcarbamazine citrate for enhanced delivery to the lymphatics: in vitro and in vivo evaluation. Expert opinion on drug delivery. 2014 Sep; 11(9):1351-65. doi: 10.1517/17425247.2014.915310. [PMID: 24847779]
  • Mark S Schmidt, Christopher L King, Edward K Thomsen, Peter M Siba, Nelly Sanuku, Lawrence Fleckenstein. Liquid chromatography-mass spectrometry analysis of diethylcarbamazine in human plasma for clinical pharmacokinetic studies. Journal of pharmaceutical and biomedical analysis. 2014 Sep; 98(?):307-10. doi: 10.1016/j.jpba.2014.05.016. [PMID: 24975211]
  • Hideharu Hagiya, Tomohiro Terasaka, Kosuke Kimura, Asuka Satou, Kikuko Asano, Koichi Waseda, Yoshihisa Hanayama, Takahide Takahashi, Michinori Aoe, Koji Iio, Toshiyuki Watanabe, Eisei Kondo, Fumio Otsuka. Filarial chyluria as a rare cause of urinary retention. Internal medicine (Tokyo, Japan). 2014; 53(17):2001-5. doi: 10.2169/internalmedicine.53.2572. [PMID: 25175138]
  • Vishal Golay, Puneet Arora, Anila Abraham, Rajendra Pandey. Quiz page November 2013: an unusual cause of nephrotic syndrome: minimal change disease (MCD). American journal of kidney diseases : the official journal of the National Kidney Foundation. 2013 Nov; 62(5):xxvii-xxix. doi: 10.1053/j.ajkd.2013.06.027. [PMID: 24157278]
  • Jai B Mullerpattan, Zarir F Udwadia, Farokh E Udwadia. Tropical pulmonary eosinophilia--a review. The Indian journal of medical research. 2013 Sep; 138(3):295-302. doi: . [PMID: 24135173]
  • T Sankari, S L Hoti, L K Das, V Govindaraj, P K Das. Effect of Diethylcarbamazine (DEC) on prostaglandin levels in Wuchereria bancrofti infected microfilaraemics. Parasitology research. 2013 Jun; 112(6):2353-9. doi: 10.1007/s00436-013-3399-y. [PMID: 23525692]
  • Komal Kalani, Vikas Kushwaha, Richa Verma, P Kalpana Murthy, S K Srivastava. Glycyrrhetinic acid and its analogs: a new class of antifilarial agents. Bioorganic & medicinal chemistry letters. 2013 May; 23(9):2566-70. doi: 10.1016/j.bmcl.2013.02.115. [PMID: 23541646]
  • Gary O Rankin, Suk K Hong, Dianne K Anestis, John G Ball, Monica A Valentovic, Vincent A Graffeo. Role of leukotrienes in N-(3,5-dichlorophenyl)succinimide (NDPS) and NDPS metabolite nephrotoxicity in male Fischer 344 rats. Toxicology. 2012 Oct; 300(1-2):92-9. doi: 10.1016/j.tox.2012.06.003. [PMID: 22706168]
  • Carlos E Medina-De la Garza, Graciela Guerrero-Ramírez, Marisela García-Hernández, M Angeles Castro-Corona, Ernesto Torres-López, Norbert W Brattig, Mario C Salinas-Carmona. Immunomodulatory activity of diethylcarbamazine on humoral, cellular cytokine response and respiratory burst in BALB/c mice. Immunopharmacology and immunotoxicology. 2012 Jun; 34(3):477-83. doi: 10.3109/08923973.2011.630008. [PMID: 22564175]
  • Koneni V Sashidhara, Suriya P Singh, Sweta Misra, Jyoti Gupta, Shailja Misra-Bhattacharya. Galactolipids from Bauhinia racemosa as a new class of antifilarial agents against human lymphatic filarial parasite, Brugia malayi. European journal of medicinal chemistry. 2012 Apr; 50(?):230-5. doi: 10.1016/j.ejmech.2012.01.057. [PMID: 22348826]
  • Makoto Itoh, Mirani V Weerasooriya, Thishan C Yahathugoda, Hidekazu Takagi, Wilfred A Samarawickrema, Fumiaki Nagaoka, Eisaku Kimura. Effects of 5 rounds of mass drug administration with diethylcarbamazine and albendazole on filaria-specific IgG4 titers in urine: 6-year follow-up study in Sri Lanka. Parasitology international. 2011 Dec; 60(4):393-7. doi: 10.1016/j.parint.2011.06.019. [PMID: 21723413]
  • Ritu Verma, Mukul Vij. Microfilariae of Wuchereria bancrofti in urine: an uncommon finding. Diagnostic cytopathology. 2011 Nov; 39(11):847-8. doi: 10.1002/dc.21562. [PMID: 21994197]
  • Delynn M Moss, Jeffrey W Priest, Alexis Boyd, Tiffany Weinkopff, Zuzana Kucerova, Michael J Beach, Patrick J Lammie. Multiplex bead assay for serum samples from children in Haiti enrolled in a drug study for the treatment of lymphatic filariasis. The American journal of tropical medicine and hygiene. 2011 Aug; 85(2):229-37. doi: 10.4269/ajtmh.2011.11-0029. [PMID: 21813840]
  • Hemanta Kumar Nayak, Mradul Kumar Daga, Sandeep kumar Garg, Nitin kumar Sinha, Rakshit Kumar, Pankaj Kumar Mohanty, Binay Kumar Pandey. A rare case of reversible acquired AA-type renal amyloidosis in a chronic filariasis patient receiving antifilarial therapy. Clinical and experimental nephrology. 2011 Aug; 15(4):591-5. doi: 10.1007/s10157-011-0448-7. [PMID: 21519822]
  • Debidas Ray, S Harikrishna, Chandra Immanuel, Lalitha Victor, Sudha Subramanyam, V Kumaraswami. Acquired alpha 1-antitrypsin deficiency in tropical pulmonary eosinophilia. The Indian journal of medical research. 2011 Jul; 134(?):79-82. doi: NULL. [PMID: 21808138]
  • Wafa'a A Al-Khamees, Michael D Schwartz, Saleh Alrashdi, Adam D Algren, Brent W Morgan. Status epilepticus associated with borage oil ingestion. Journal of medical toxicology : official journal of the American College of Medical Toxicology. 2011 Jun; 7(2):154-7. doi: 10.1007/s13181-011-0135-9. [PMID: 21387119]
  • Moshe Shenker, Daniella Harush, Julius Ben-Ari, Benny Chefetz. Uptake of carbamazepine by cucumber plants--a case study related to irrigation with reclaimed wastewater. Chemosphere. 2011 Feb; 82(6):905-10. doi: 10.1016/j.chemosphere.2010.10.052. [PMID: 21071061]
  • G A El-Shahawi, M Abdel-Latif, A H Saad, M Bahgat. Setaria equina: in vivo effect of diethylcarbamazine citrate on microfilariae in albino rats. Experimental parasitology. 2010 Dec; 126(4):603-10. doi: 10.1016/j.exppara.2010.06.022. [PMID: 20599991]
  • Vivornpun Sanprasert, Anupong Sujariyakul, Surang Nuchprayoon. A single dose of doxycycline in combination with diethylcarbamazine for treatment of bancroftian filariasis. The Southeast Asian journal of tropical medicine and public health. 2010 Jul; 41(4):800-12. doi: . [PMID: 21073054]
  • L C Alves, M G S Cavalcanti, H R C Araújo, G M Silva, D L Veras, M H S Paiva, F A Brayner. Ultrastructural analysis of microfilariae of Wuchereria bancrofti obtained from persistent carriers after repeated courses of diethylcarbamazine. Micron (Oxford, England : 1993). 2009 Jul; 40(5-6):659-64. doi: 10.1016/j.micron.2009.01.004. [PMID: 19359187]
  • Nina O Nielsen, Paul E Simonsen, Pernille Kaestel, Henrik Krarup, Pascal Magnussen, Stephen Magesa, Henrik Friis. Micronutrient status indicators in individuals single- or double-infected with HIV and Wuchereria bancrofti before and after DEC treatment. Tropical medicine & international health : TM & IH. 2009 Jan; 14(1):44-53. doi: 10.1111/j.1365-3156.2008.02180.x. [PMID: 19017312]
  • Karina Lidianne Alcântara Saraiva, Valdemiro Amaro Da Silva, Dilênia De Oliveira Cipriano Torres, Mariana Aragão Matos Donato, Newton Gil Peres, José Roberto Botelho De Souza, Christina Alves Peixoto. Changes in mouse Leydig cells ultrastructure and testosterone secretion after diethylcarbamazine administration. Micron (Oxford, England : 1993). 2008 Jul; 39(5):580-6. doi: 10.1016/j.micron.2007.06.003. [PMID: 17681769]
  • Anna S Kerketta, Kalpataru Dhal, Rabindranatha Nayak. A successful outcome of gross haematuria treated with diethylcarbamazine and ivermectin. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2008 May; 102(5):506-7. doi: 10.1016/j.trstmh.2008.02.008. [PMID: 18359500]
  • N K Gunawardena, N D D M Amarasekera, A Pathmeswaran, N R de Silva. Effect of repeated mass chemotherapy for filariasis control on soil-transmitted helminth infections in Sri Lanka. The Ceylon medical journal. 2008 Mar; 53(1):13-6. doi: 10.4038/cmj.v53i1.220. [PMID: 18590264]
  • Karina Lidianne Alcântara Saraiva, Valdemiro Amaro Junior Silva, Elisângela Santos Ferreira Dias, Christina Alves Peixoto. Morphological changes in the testis induced by diethylcarbamazine. Reproductive toxicology (Elmsford, N.Y.). 2006 Nov; 22(4):754-9. doi: 10.1016/j.reprotox.2006.07.008. [PMID: 17005367]
  • Shizugi Shigeno, Yasunori Fujimaki, Kanan Toriyama, Akitoyo Ichinose, Yoshinori Mitsui, Yoshiki Aoki, Eisaku Kimura. Temporary shift of microfilariae of Brugia pahangi from the lungs to muscles in Mongolian jirds, Meriones unguiculatus, after a single injection of diethylcarbamazine. The Journal of parasitology. 2006 Oct; 92(5):1075-80. doi: 10.1645/ge-842r.1. [PMID: 17152953]
  • W H Makunde, M L Kamugisha, R A Makunde, M N Malecela-Lazaro, A Y Kitua. Implication of diethylcarbamazine induced morbidity and the role of cellular responses associated with bancroftian filariasis pathologies. Tanzania health research bulletin. 2006 Jan; 8(1):11-6. doi: 10.4314/thrb.v8i1.14264. [PMID: 17058794]
  • M A Khan, R L Gaur, S Dixit, M Saleemuddin, P K Murthy. Responses of Mastomys coucha, that have been infected with Brugia malayi and treated with diethylcarbamazine or albendazole, to re-exposure to infection. Annals of tropical medicine and parasitology. 2004 Dec; 98(8):817-30. doi: 10.1179/136485904x12386. [PMID: 15667714]
  • Andrea K Boggild, Jay S Keystone, Kevin C Kain. Tropical pulmonary eosinophilia: a case series in a setting of nonendemicity. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2004 Oct; 39(8):1123-8. doi: 10.1086/423964. [PMID: 15486834]
  • Madsen Beau De Rochars, Abdel N Direny, Jacquelin M Roberts, David G Addiss, Jeanne Radday, Michael J Beach, Thomas G Streit, Desire Dardith, Jack Guy Lafontant, Patrick J Lammie. Community-wide reduction in prevalence and intensity of intestinal helminths as a collateral benefit of lymphatic filariasis elimination programs. The American journal of tropical medicine and hygiene. 2004 Oct; 71(4):466-70. doi: 10.4269/ajtmh.2004.71.466. [PMID: 15516644]
  • N A Kshirsagar, N J Gogtay, B S Garg, P R Deshmukh, D D Rajgor, V S Kadam, B G Kirodian, N S Ingole, A M Mehendale, L Fleckenstein, J Karbwang, J K Lazdins-Helds. Safety, tolerability, efficacy and plasma concentrations of diethylcarbamazine and albendazole co-administration in a field study in an area endemic for lymphatic filariasis in India. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2004 Apr; 98(4):205-17. doi: 10.1016/s0035-9203(03)00044-0. [PMID: 15049459]
  • John R Burnett, Gary G Sturdy, Suzzanne J Smith, Yuli Ten, Michael J McComish. 'Milky' urine: a case of chyluria. The Medical journal of Australia. 2004 Jan; 180(2):89. doi: 10.5694/j.1326-5377.2004.tb05808.x. [PMID: 14768633]
  • Herbert Auer, Horst Aspöck. [Nosology and epidemiology of human toxocarosis--the recent situation in Austria]. Wiener klinische Wochenschrift. 2004; 116 Suppl 4(?):7-18. doi: NULL. [PMID: 15683037]
  • Katsutoshi Yokoi, Hiroshi Goto, Jun-ichi Sakai, Masahiko Usui. Clinical features of ocular toxocariasis in Japan. Ocular immunology and inflammation. 2003 Dec; 11(4):269-75. doi: 10.1076/ocii.11.4.269.18266. [PMID: 14704898]
  • N R De Silva, A Pathmeswaran, S D Fernando, C R Weerasinghe, R R Selvaratnam, E A Padmasiri, A Montresor. Impact of mass chemotherapy for the control of filariasis on geohelminth infections in Sri Lanka. Annals of tropical medicine and parasitology. 2003 Jun; 97(4):421-5. doi: 10.1179/000349803235002407. [PMID: 12831528]
  • R Rajendran, T R Mani, A Munirathinam, I P Sunish, S Md Abdullah, D J Augustin, K Satyanarayana. Sustainability of soil-transmitted helminth control following a single-dose co-administration of albendazole and diethylcarbamazine. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2003 May; 97(3):355-9. doi: 10.1016/s0035-9203(03)90168-4. [PMID: 15228259]
  • R K Shenoy, T K Suma, A John, S R Arun, V Kumaraswami, L L Fleckenstein, K Na-Bangchang. The pharmacokinetics, safety and tolerability of the co-administration of diethylcarbamazine and albendazole. Annals of tropical medicine and parasitology. 2002 Sep; 96(6):603-14. doi: 10.1179/000349802125001663. [PMID: 12396323]
  • Paul B Keiser, Stacey M Reynolds, Kwablah Awadzi, Eric A Ottesen, Mark J Taylor, Thomas B Nutman. Bacterial endosymbionts of Onchocerca volvulus in the pathogenesis of posttreatment reactions. The Journal of infectious diseases. 2002 Mar; 185(6):805-11. doi: 10.1086/339344. [PMID: 11920298]
  • Sambamoorthy Bolla, Ramesh R Boinpally, Srinivasu Poondru, Rambhau Devaraj, Bhaskara R Jasti. Pharmacokinetics of diethylcarbamazine after single oral dose at two different times of day in human subjects. Journal of clinical pharmacology. 2002 Mar; 42(3):327-31. doi: 10.1177/00912700222011247. [PMID: 11865970]
  • A R Freeman, P J Lammie, R Houston, M D LaPointe, T G Streit, P L Jooste, J M Brissau, J G Lafontant, D G Addiss. A community-based trial for the control of lymphatic filariasis and iodine deficiency using salt fortified with diethylcarbamazine and iodine. The American journal of tropical medicine and hygiene. 2001 Dec; 65(6):865-71. doi: 10.4269/ajtmh.2001.65.865. [PMID: 11791989]
  • S Mohan, C G Pradeep, R Abhilash Kumar, K Jayakumar, R Kaleysa Raj. The adult-specific ubiquinone Q(8) functions as an antioxidant in the filarial parasite, Setaria digitata. Biochemical and biophysical research communications. 2001 Nov; 288(4):949-53. doi: 10.1006/bbrc.2001.5882. [PMID: 11689001]
  • J R Miller, L Fleckenstein. Gas chromatographic assay of diethylcarbamazine in human plasma for application to clinical pharmacokinetic studies. Journal of pharmaceutical and biomedical analysis. 2001 Nov; 26(4):665-74. doi: 10.1016/s0731-7085(01)00435-6. [PMID: 11516918]
  • H Nomura, E Sato, S Koyama, M Haniuda, K Kubo, S Nagai, T Izumi. Histamine stimulates alveolar macrophages to release neutrophil and monocyte chemotactic activity. The Journal of laboratory and clinical medicine. 2001 Oct; 138(4):226-35. doi: 10.1067/mlc.2001.117988. [PMID: 11574816]
  • J K Grover, V Vats, G Uppal, S Yadav. Anthelmintics: a review. Tropical gastroenterology : official journal of the Digestive Diseases Foundation. 2001 Oct; 22(4):180-9. doi: . [PMID: 11963321]
  • P Bernhard, P Magnussen, M M Lemnge. A randomized, double-blind, placebo-controlled study with diethylcarbamazine for the treatment of hydrocoele in an area of Tanzania endemic for lymphatic filariasis. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2001 Sep; 95(5):534-6. doi: 10.1016/s0035-9203(01)90031-8. [PMID: 11706668]
  • P Esterre, C Plichart, Y Sechan, N L Nguyen. The impact of 34 years of massive DEC chemotherapy on Wuchereria bancrofti infection and transmission: the Maupiti cohort. Tropical medicine & international health : TM & IH. 2001 Mar; 6(3):190-5. doi: 10.1046/j.1365-3156.2001.00682.x. [PMID: 11299035]
  • M J Beach, T G Streit, R Houston, W A May, D G Addiss, P J Lammie. Short report: documentation of iodine deficiency in Haitian schoolchildren: implication for lymphatic filariasis elimination in Haiti. The American journal of tropical medicine and hygiene. 2001 Jan; 64(1-2):56-7. doi: 10.4269/ajtmh.2001.64.56. [PMID: 11425163]
  • O E Orisakwe, N D Ilondu, O J Afonne, S I Ofoefule, C N Orish, P U Agbasi. Effect of activated charcoal on diethylcarbamazine absorption in humans. American journal of therapeutics. 2001 Jan; 8(1):7-9. doi: 10.1097/00045391-200101000-00003. [PMID: 11304652]
  • M Haarbrink, G K Abadi, W A Buurman, M A Dentener, A J Terhell, M Yazdanbakhsh. Strong association of interleukin-6 and lipopolysaccharide-binding protein with severity of adverse reactions after diethylcarbamazine treatment of microfilaremic patients. The Journal of infectious diseases. 2000 Aug; 182(2):564-9. doi: 10.1086/315735. [PMID: 10915090]
  • O E Orisakwe, N A Ilondu, O J Afonne, S I Ofoefule, C N Orish. Acceleration of body clearance of diethylCarbamazine by oral activated charcoal. Pharmacological research. 2000 Aug; 42(2):167-70. doi: 10.1006/phrs.2000.0667. [PMID: 10887047]
  • N Ilondu, O E Orisakwe, S Ofoefule, O J Afonne, E Obi, K C Chilaka, C Orish. Pharmacokinetics of diethylcarbamazine: prediction by concentration in saliva. Biological & pharmaceutical bulletin. 2000 Apr; 23(4):443-5. doi: 10.1248/bpb.23.443. [PMID: 10784424]
  • M R Pinsky, A Roman, W Buurman, J Content, J L Vincent. Effect of ibuprofen and diethylcarbamazine on the hemodynamic and inflammatory response to endotoxin in the dog. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes. 2000; 32(2):74-86. doi: 10.1159/000008744. [PMID: 10810212]
  • R Gopinath, L E Hanna, V Kumaraswami, V Perumal, V Kavitha, V Vijayasekaran, T B Nutman. Perturbations in eosinophil homeostasis following treatment of lymphatic filariasis. Infection and immunity. 2000 Jan; 68(1):93-9. doi: 10.1128/iai.68.1.93-99.2000. [PMID: 10603373]
  • M Haarbrink, A J Terhell, G K Abadi, Y Mitsui, M Yazdanbakhsh. Inflammatory cytokines following diethylcarbamazine (DEC) treatment of different clinical groups in lymphatic filariasis. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1999 Nov; 93(6):665-72. doi: 10.1016/s0035-9203(99)90093-7. [PMID: 10717762]
  • H Koyama, N Sugioka, A Uno, S Mori, K Nakajima. Age-related alteration of carbamazepine-serum protein binding in man. The Journal of pharmacy and pharmacology. 1999 Sep; 51(9):1009-14. doi: 10.1211/0022357991773474. [PMID: 10528982]
  • J H Cooray, M M Ismail. Re-examination of the diagnostic criteria of tropical pulmonary eosinophilia. Respiratory medicine. 1999 Sep; 93(9):655-9. doi: 10.1016/s0954-6111(99)90106-3. [PMID: 10542980]
  • M M Ismail, R L Jayakody. Efficacy of albendazole and its combinations with ivermectin or diethylcarbamazine (DEC) in the treatment of Trichuris trichiura infections in Sri Lanka. Annals of tropical medicine and parasitology. 1999 Jul; 93(5):501-4. doi: 10.1080/00034989958230. [PMID: 10690245]
  • M Haarbrink, A J Terhell, G K Abadi, Y Mitsui, M Yazdanbakhsh. Adverse reactions following diethylcarbamazine (DEC) intake in 'endemic normals', microfilaraemics and elephantiasis patients. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1999 Jan; 93(1):91-6. doi: 10.1016/s0035-9203(99)90194-3. [PMID: 10492800]
  • W A Daniel, M Syrek, A Haduch, J Wójcikowski. Pharmacokinetics of phenothiazine neuroleptics after chronic coadministration of carbamazepine. Polish journal of pharmacology. 1998 Nov; 50(6):431-42. doi: NULL. [PMID: 10385926]
  • S Koyama, E Sato, T Masubuchi, A Takamizawa, H Nomura, K Kubo, S Nagai, T Izumi. Human lung fibroblasts release chemokinetic activity for monocytes constitutively. The American journal of physiology. 1998 08; 275(2):L223-30. doi: 10.1152/ajplung.1998.275.2.l223. [PMID: 9700081]
  • J L Tojo, M T Santamarina. Oral pharmacological treatments for parasitic diseases of rainbow trout Oncorhynchus mykiss. I: Hexamita salmonis. Diseases of aquatic organisms. 1998 May; 33(1):51-6. doi: 10.3354/dao033051. [PMID: 9653458]
  • Y Mitsui, Y Aoki. A direct competitive ELISA for the simple, sensitive and accurate determination of diethylcarbamazine concentration in serum. International journal for parasitology. 1998 Apr; 28(4):623-6. doi: 10.1016/s0020-7519(97)00205-1. [PMID: 9602386]
  • T V Rajan, L D Shultz, S Babu, J Doukas, D Greiner, P Porte. Diethylcarbamazine (DEC) does not induce nitric oxide (NO) synthesis. Experimental parasitology. 1998 Mar; 88(3):217-22. doi: 10.1006/expr.1998.4247. [PMID: 9562425]
  • A Daugschies, B Ruttkowski. Modulation of migration of Oesophagostomum dentatum larvae by inhibitors and products of eicosanoid metabolism. International journal for parasitology. 1998 Feb; 28(2):355-62. doi: 10.1016/s0020-7519(97)00153-7. [PMID: 9513001]
  • S Lee, D A Casteel, L Fleckenstein. Specific gas chromatographic analysis of diethylcarbamazine in human plasma using solid-phase extraction. Journal of chromatography. B, Biomedical sciences and applications. 1997 Dec; 704(1-2):181-5. doi: 10.1016/s0378-4347(97)00424-6. [PMID: 9518148]
  • Y Horii, Y Aoki. Plasma levels of diethylcarbamazine and their effects on implanted microfilariae of Brugia pahangi in rats. The Journal of veterinary medical science. 1997 Oct; 59(10):961-3. doi: 10.1292/jvms.59.961. [PMID: 9362054]
  • J Langhammer, H W Birk, H Zahner. Renal disease in lymphatic filariasis: evidence for tubular and glomerular disorders at various stages of the infection. Tropical medicine & international health : TM & IH. 1997 Sep; 2(9):875-84. doi: 10.1046/j.1365-3156.1997.d01-404.x. [PMID: 9315046]
  • C Bhattacharya, R N Singh, S Misra, S Rathaur. Diethylcarbamazine: effect on lysosomal enzymes and acetylcholine in Wuchereria bancrofti infection. Tropical medicine & international health : TM & IH. 1997 Jul; 2(7):686-90. doi: 10.1046/j.1365-3156.1997.d01-353.x. [PMID: 9270736]
  • S Mukhopadhyay, B Ravindran. Antibodies to diethylcarbamazine potentiate the antifilarial activity of the drug. Parasite immunology. 1997 Apr; 19(4):191-5. doi: 10.1046/j.1365-3024.1997.d01-192.x. [PMID: 9149286]
  • R López-Vélez, M C Turrientes, Q Malo, M S Fenoy, J L Guillén. [2 cases of toxocariasis (visceral larva migrans)]. Enfermedades infecciosas y microbiologia clinica. 1996 Nov; 14(9):548-50. doi: NULL. [PMID: 9035713]
  • Y Mitsui, N Takamura, Y Fujimaki, T Yamaguchi, T Kitagawa, Y Aoki. Development of a competitive enzyme-linked immunosorbent assay for diethylcarbamazine. Tropical medicine & international health : TM & IH. 1996 Aug; 1(4):528-34. doi: 10.1046/j.1365-3156.1996.d01-77.x. [PMID: 8765462]
  • J B Hagan, K R Bartemes, H Kita, E A Ottesen, K Awadzi, T B Nutman, G J Gleich. Elevations in granulocyte-macrophage colony-stimulating factor and interleukin-5 levels precede posttreatment eosinophilia in onchocerciasis. The Journal of infectious diseases. 1996 May; 173(5):1277-80. doi: 10.1093/infdis/173.5.1277. [PMID: 8627086]
  • J W Jaroszewski, D Berenstein, F A Sløk, P E Simonsen, M K Agger. Determination of diethylcarbamazine, an antifilarial drug, in human urine by 1H-NMR spectroscopy. Journal of pharmaceutical and biomedical analysis. 1996 Mar; 14(5):543-9. doi: 10.1016/0731-7085(95)01664-3. [PMID: 8738183]
  • I Cernak, J Savic, Z Malicevic, G Zunic, P Radosevic, I Ivanovic. Leukotrienes in the pathogenesis of pulmonary blast injury. The Journal of trauma. 1996 Mar; 40(3 Suppl):S148-51. doi: 10.1097/00005373-199603001-00032. [PMID: 8606397]
  • A K Atmadja, R Atkinson, E Sartono, F Partono, M Yazdanbakhsh, R M Maizels. Differential decline in filaria-specific IgG1, IgG4, and IgE antibodies in Brugia malayi-infected patients after diethylcarbamazine chemotherapy. The Journal of infectious diseases. 1995 Dec; 172(6):1567-72. doi: 10.1093/infdis/172.6.1567. [PMID: 7594718]