Pyrantel pamoate (BioDeep_00000015060)
代谢物信息卡片
Pyrantel pamoate
化学式: C34H30N2O6S (594.182448)
中文名称: 双羟萘酸噻嘧啶
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1CCCN=C1C=CC2=CC=CS2.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O
InChI: 6-5+
描述信息
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics
C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent
Pyrantel pamoate (Pyrantel embonate) is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel pamoate can cause spasmodic muscle paralysis in parasites. Pyrantel pamoate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis[1][2].
同义名列表
3 个代谢物同义名
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:8655
- KEGG: C07389
- KEGGdrug: D00486
- PubChem: 5281033
- ChEMBL: CHEMBL1599768
- MeSH: Pyrantel Pamoate
- CAS: 22204-24-6
- PubChem: 9593
- medchemexpress: HY-12640
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Beatrice Barda, Christian Schindler, Rahel Wampfler, Shaali Ame, Said M Ali, Jennifer Keiser. Comparison of real-time PCR and the Kato-Katz method for the diagnosis of soil-transmitted helminthiasis and assessment of cure in a randomized controlled trial.
BMC microbiology.
2020 10; 20(1):298. doi:
10.1186/s12866-020-01963-9. [PMID: 33008301] - Jennifer L Cain, Donna Foulk, Edward Jedrzejewski, Heather Stofanak, Martin K Nielsen. The importance of anthelmintic efficacy monitoring: results of an outreach effort.
Parasitology research.
2019 Oct; 118(10):2877-2883. doi:
10.1007/s00436-019-06423-6. [PMID: 31422463] - Jessica D Schulz, Anna Neodo, Jean T Coulibaly, Jennifer Keiser. Pharmacokinetics of Albendazole, Albendazole Sulfoxide, and Albendazole Sulfone Determined from Plasma, Blood, Dried-Blood Spots, and Mitra Samples of Hookworm-Infected Adolescents.
Antimicrobial agents and chemotherapy.
2019 04; 63(4):. doi:
10.1128/aac.02489-18. [PMID: 30745388] - Anna Neodo, Jessica D Schulz, Jörg Huwyler, Jennifer Keiser. In Vitro and In Vivo Drug-Drug Interaction Study of the Effects of Ivermectin and Oxantel Pamoate on Tribendimidine.
Antimicrobial agents and chemotherapy.
2019 01; 63(1):. doi:
10.1128/aac.00762-18. [PMID: 30323047] - Pierre H H Schneeberger, Jean T Coulibaly, Morgan Gueuning, Wendelin Moser, Bryan Coburn, Jürg E Frey, Jennifer Keiser. Off-target effects of tribendimidine, tribendimidine plus ivermectin, tribendimidine plus oxantel-pamoate, and albendazole plus oxantel-pamoate on the human gut microbiota.
International journal for parasitology. Drugs and drug resistance.
2018 12; 8(3):372-378. doi:
10.1016/j.ijpddr.2018.07.001. [PMID: 30007544] - Alexandra Arion, Emilio Fernández-Varón, Carlos M Cárceles, László Gagyi, Laurent Ognean. Pharmacokinetics of praziquantel and pyrantel pamoate combination following oral administration in cats.
Journal of feline medicine and surgery.
2018 10; 20(10):900-904. doi:
10.1177/1098612x17734065. [PMID: 29017390] - Ž Vienažindienė, D E Joekel, R Schaper, P Deplazes, M Šarkūnas. Longitudinal study for anthelmintic efficacy against intestinal helminths in naturally exposed Lithuanian village dogs: critical analysis of feasibility and limitations.
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2012 Jul; 60(7):446-8. doi:
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Journal of colloid and interface science.
2010 Oct; 350(1):330-5. doi:
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2010 Jul; 171(1-2):106-10. doi:
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2009 Apr; 161(1-2):138-41. doi:
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2007 Apr; 145(3-4):371-6. doi:
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2006 Apr; 137(3-4):369-73. doi:
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