Movens (BioDeep_00000015027)
代谢物信息卡片
Meclomen
化学式: C14H10Cl2NNaO2 (316.99862600000006)
中文名称: 甲氯芬那酸钠水合物
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)[O-])Cl.[Na+]
InChI: /q
描述信息
D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000893 - Anti-Inflammatory Agents
D004791 - Enzyme Inhibitors
同义名列表
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:6711
- KEGG: C02996
- KEGGdrug: D08162
- KEGGdrug: D81964
- PubChem: 4038
- ChEMBL: CHEMBL876
- MeSH: Meclofenamic Acid
- CAS: 6385-02-0
- PubChem: 5905
- NIKKAJI: J8.403D
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Amalia Barmpa, George D Geromichalos, Antonios G Hatzidimitriou, George Psomas. Nickel(II)-meclofenamate complexes: Structure, in vitro and in silico DNA- and albumin-binding studies, antioxidant and anticholinergic activity.
Journal of inorganic biochemistry.
2021 09; 222(?):111507. doi:
10.1016/j.jinorgbio.2021.111507. [PMID: 34139455] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Amalia Barmpa, Antonios G Hatzidimitriou, George Psomas. Copper(II) complexes with meclofenamate ligands: Structure, interaction with DNA and albumins, antioxidant and anticholinergic activity.
Journal of inorganic biochemistry.
2021 04; 217(?):111357. doi:
10.1016/j.jinorgbio.2021.111357. [PMID: 33556771] - Emmanuelle Soleilhac, Marjorie Comte, Anaelle da Costa, Caroline Barette, Christèle Picoli, Magda Mortier, Laurence Aubry, Franck Mouthon, Marie-Odile Fauvarque, Mathieu Charvériat. Quantitative Automated Assays in Living Cells to Screen for Inhibitors of Hemichannel Function.
SLAS discovery : advancing life sciences R & D.
2021 03; 26(3):420-427. doi:
10.1177/2472555220954388. [PMID: 32914684] - Peihui Zhou, Ming Wu, Chaoyang Ye, Qingqing Xu, Li Wang. Meclofenamic acid promotes cisplatin-induced acute kidney injury by inhibiting fat mass and obesity-associated protein-mediated m6A abrogation in RNA.
The Journal of biological chemistry.
2019 11; 294(45):16908-16917. doi:
10.1074/jbc.ra119.011009. [PMID: 31578283] - Hussin A Rothan, Hirbod Bahrani, Ammar Y Abdulrahman, Zulqarnain Mohamed, Teow Chong Teoh, Shatrah Othman, Nurshamimi Nor Rashid, Noorsaadah A Rahman, Rohana Yusof. Mefenamic acid in combination with ribavirin shows significant effects in reducing chikungunya virus infection in vitro and in vivo.
Antiviral research.
2016 Mar; 127(?):50-6. doi:
10.1016/j.antiviral.2016.01.006. [PMID: 26794398] - Chika Saigo, Yui Nomura, Yuko Yamamoto, Masataka Sagata, Rika Matsunaga, Hirofumi Jono, Kazuhiko Nishi, Hideyuki Saito. Meclofenamate elicits a nephropreventing effect in a rat model of ischemic acute kidney injury by suppressing indoxyl sulfate production and restoring renal organic anion transporters.
Drug design, development and therapy.
2014; 8(?):1073-82. doi:
10.2147/dddt.s67456. [PMID: 25143712] - Yuji Narukawa, Akiko Niimura, Hitomi Noguchi, Hiroomi Tamura, Fumiyuki Kiuchi. New diterpenoids with estrogen sulfotransferase inhibitory activity from Leonurus sibiricus L.
Journal of natural medicines.
2014 Jan; 68(1):125-31. doi:
10.1007/s11418-013-0781-0. [PMID: 23736977] - Sungwook Choi, Jeffery W Kelly. A competition assay to identify amyloidogenesis inhibitors by monitoring the fluorescence emitted by the covalent attachment of a stilbene derivative to transthyretin.
Bioorganic & medicinal chemistry.
2011 Feb; 19(4):1505-14. doi:
10.1016/j.bmc.2010.12.050. [PMID: 21273081] - S I Gomez, D M Strick, J C Romero. Role of nitric oxide and prostaglandin in the maintenance of cortical and renal medullary blood flow.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
2008 Feb; 41(2):170-5. doi:
10.1590/s0100-879x2008000200014. [PMID: 18297197] - Yoshie S Weems, Laurie Kim, Vicki Tsuda, Chaoquan Yin, Charles W Weems. What regulates placental steroidogenesis in 90-day pregnant ewes?.
Prostaglandins & other lipid mediators.
2007 Aug; 84(1-2):54-65. doi:
10.1016/j.prostaglandins.2007.04.002. [PMID: 17643888] - M A Popot, L Menaut, S Boyer, Y Bonnaire, P L Toutain. Spurious urine excretion drug profile in the horse due to bedding contamination and drug recycling: the case of meclofenamic acid.
Journal of veterinary pharmacology and therapeutics.
2007 Apr; 30(2):179-84. doi:
10.1111/j.1365-2885.2007.00835.x. [PMID: 17348907] - Allison L Opay, Cynthia R Mouton, John J Mullins, Kenneth D Mitchell. Cyclooxygenase-2 inhibition normalizes arterial blood pressure in CYP1A1-REN2 transgenic rats with inducible ANG II-dependent malignant hypertension.
American journal of physiology. Renal physiology.
2006 Sep; 291(3):F612-8. doi:
10.1152/ajprenal.00032.2006. [PMID: 16622181] - A Muñoz de la Peña, A Espinosa Mansilla, N Mora Díez, D Bohoyo Gil, A C Olivieri, G M Escandar. Second-order calibration of excitation-emission matrix fluorescence spectra for the determination of N-phenylanthranilic acid derivatives.
Applied spectroscopy.
2006 Mar; 60(3):330-8. doi:
10.1366/000370206776342643. [PMID: 16608576] - Kiyoshi Shimizu, Kanji Matsukawa, Jun Murata, Hirotsugu Tsuchimochi, Ishio Ninomiya. Partial renal ischemia elicits heterogeneous control of renal sympathetic nerve activity to ischemic and nonischemic regions of the kidney.
American journal of physiology. Regulatory, integrative and comparative physiology.
2006 Feb; 290(2):R322-30. doi:
10.1152/ajpregu.00493.2005. [PMID: 16166203] - Jason M Hoover, Alan D Kaye, Ikhlass N Ibrahim, Aaron M Fields, Todd A Richards. Analysis of responses to kava kava in the feline pulmonary vascular bed.
Journal of medicinal food.
2006; 9(1):62-71. doi:
10.1089/jmf.2006.9.62. [PMID: 16579730] - M B Kadiiska, B C Gladen, D D Baird, L B Graham, C E Parker, B N Ames, S Basu, G A Fitzgerald, J A Lawson, L J Marnett, J D Morrow, D M Murray, J Plastaras, L J Roberts, J Rokach, M K Shigenaga, J Sun, P B Walter, K B Tomer, J C Barrett, R P Mason. Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning.
Free radical biology & medicine.
2005 Mar; 38(6):711-8. doi:
10.1016/j.freeradbiomed.2004.10.024. [PMID: 15721981] - Julian A Skidmore, M Billah. Embryo transfer in the dromedary camel (Camelus dromedarius) using asynchronous, meclofenamic acid-treated recipients.
Reproduction, fertility, and development.
2005; 17(4):417-21. doi:
10.1071/rd04081. [PMID: 15899153] - Jason M Hoover, Alan D Kaye, Ikhlass N Ibrahim, Aaron M Fields, Todd A Richards. Analysis of responses to St. John's Wort in the feline pulmonary vascular bed.
Journal of herbal pharmacotherapy.
2004; 4(3):47-62. doi:
. [PMID: 15829469] - Francisca Rodriguez, Rowena Kemp, Michael Balazy, Alberto Nasjletti. Effects of exogenous heme on renal function: role of heme oxygenase and cyclooxygenase.
Hypertension (Dallas, Tex. : 1979).
2003 Oct; 42(4):680-4. doi:
10.1161/01.hyp.0000085785.40581.1a. [PMID: 12900432] - Carlos Gomez-Alamillo, Luis A Juncos, Aleix Cases, John A Haas, J Carlos Romero. Interactions between vasoconstrictors and vasodilators in regulating hemodynamics of distinct vascular beds.
Hypertension (Dallas, Tex. : 1979).
2003 Oct; 42(4):831-6. doi:
10.1161/01.hyp.0000088854.04562.da. [PMID: 12925563] - Jason L Eriksen, Sarah A Sagi, Tawnya E Smith, Sascha Weggen, Pritam Das, D C McLendon, Victor V Ozols, Kevin W Jessing, Kenton H Zavitz, Edward H Koo, Todd E Golde. NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo.
The Journal of clinical investigation.
2003 Aug; 112(3):440-9. doi:
10.1172/jci18162. [PMID: 12897211] - Wolfgang Schober, Rainer Kehlbach, Regina Gebert, Jakub Wiskirchen, Enno Rodegerdts, Claus D Claussen, Stephan H Duda. Meclofenamic acid for inhibition of human vascular smooth muscle cell proliferation and migration: an in vitro study.
Cardiovascular and interventional radiology.
2002 Jan; 25(1):57-63. doi:
10.1007/s00270-001-0077-8. [PMID: 11907776] - R C Fowkes, C Chandras, E C Chin, S Okolo, D R Abayasekara, A E Michael. Relationship between the production of prostaglandins and progesterone by luteinizing human granulosa cells.
The Journal of endocrinology.
2001 Dec; 171(3):455-62. doi:
10.1677/joe.0.1710455. [PMID: 11739011] - M T Llinás, R López, F Rodríguez, F Roig, F J Salazar. Role of COX-2-derived metabolites in regulation of the renal hemodynamic response to norepinephrine.
American journal of physiology. Renal physiology.
2001 Nov; 281(5):F975-82. doi:
10.1152/ajprenal.2001.281.5.f975. [PMID: 11592955] - K Nakanishi, A Chinen, Y Saito, K Hamada, N Hara, Y Nagai. Nitric oxide buffers renal medullary vasoconstriction induced by prostaglandins synthesis blockade.
Hypertension research : official journal of the Japanese Society of Hypertension.
2001 Nov; 24(6):699-704. doi:
10.1291/hypres.24.699. [PMID: 11768730] - M T Llinás, F Rodríguez, C Moreno, F J Salazar. Role of cyclooxygenase-2-derived metabolites and nitric oxide in regulating renal function.
American journal of physiology. Regulatory, integrative and comparative physiology.
2000 Nov; 279(5):R1641-6. doi:
10.1152/ajpregu.2000.279.5.r1641. [PMID: 11049846] - F Rodríguez, M T Llinás, J D González, J Rivera, F J Salazar. Renal changes induced by a cyclooxygenase-2 inhibitor during normal and low sodium intake.
Hypertension (Dallas, Tex. : 1979).
2000 Aug; 36(2):276-81. doi:
10.1161/01.hyp.36.2.276. [PMID: 10948090] - M Vietri, C De Santi, A Pietrabissa, F Mosca, G M Pacifici. Fenamates and the potent inhibition of human liver phenol sulphotransferase.
Xenobiotica; the fate of foreign compounds in biological systems.
2000 Feb; 30(2):111-6. doi:
10.1080/004982500237712. [PMID: 10718119] - F Pérez-Villa, F Epelde, E Roig, M Heras, M Rigol, S Díez-Aja, M J Zurbano, G Escolar, G Sanz. [Effect of cyclooxygenase inhibition on the adaptation of coronary blood flow to tachycardia].
Revista espanola de cardiologia.
2000 Jan; 53(1):59-65. doi:
10.1016/s0300-8932(00)75064-0. [PMID: 10701324] - A Végh, K György, M A Rastegar, J G Papp, J R Parratt. Delayed protection against ventricular arrhythmias by monophosphoryl lipid-A in a canine model of ischaemia and reperfusion.
European journal of pharmacology.
1999 Oct; 382(2):81-90. doi:
10.1016/s0014-2999(99)00557-9. [PMID: 10528142] - Y S Weems, M A Lammoglia, A W Lewis, R D Randel, R G Sasser, I Morita, C W Weems. PGE2 induces its own secretion in vitro by bovine 270-day placenta but not by 200-day placenta.
Prostaglandins & other lipid mediators.
1999 Jun; 57(4):189-205. doi:
10.1016/s0090-6980(99)00003-9. [PMID: 10402214] - P Krishnamurthy, I M Bird, C Sheppard, R R Magness. Effects of angiogenic growth factors on endothelium-derived prostacyclin production by ovine uterine and placental arteries.
Prostaglandins & other lipid mediators.
1999 Jan; 57(1):1-12. doi:
10.1016/s0090-6980(98)00066-5. [PMID: 10367292] - J A Skidmore, G R Starbuck, G E Lamming, W R Allen. Control of luteolysis in the one-humped camel (Camelus dromedarius).
Journal of reproduction and fertility.
1998 Nov; 114(2):201-9. doi:
10.1530/jrf.0.1140201. [PMID: 10070348] - J D González, M T Llinás, E Nava, L Ghiadoni, F J Salazar. Role of nitric oxide and prostaglandins in the long-term control of renal function.
Hypertension (Dallas, Tex. : 1979).
1998 Jul; 32(1):33-8. doi:
10.1161/01.hyp.32.1.33. [PMID: 9674634] - T Pérez-Ruiz, C Martínez-Lozano, A Sanz, E Bravo. Determination of flufenamic, meclofenamic and mefenamic acids by capillary electrophoresis using beta-cyclodextrin.
Journal of chromatography. B, Biomedical sciences and applications.
1998 Apr; 708(1-2):249-56. doi:
10.1016/s0378-4347(97)00674-9. [PMID: 9653970] - K Yamaguchi, H Hama, K Watanabe. Possible participation of prostaglandins generated in the anteroventral third ventricular region in the hypovolemia-induced vasopressin secretion of conscious rats.
European journal of endocrinology.
1998 Feb; 138(2):206-15. doi:
10.1530/eje.0.1380206. [PMID: 9506868] - M T Llinás, J D González, F Rodríguez, E Nava, S Taddei, F J Salazar. Renal changes induced by nitric oxide and prostaglandin synthesis reduction: effects of trandolapril and verapamil.
Hypertension (Dallas, Tex. : 1979).
1998 Feb; 31(2):657-64. doi:
10.1161/01.hyp.31.2.657. [PMID: 9461237] - P T Murray, M E Wylam, J G Umans. Endotoxin impairs agonist-induced calcium mobilization in rat mesangial cells.
American journal of respiratory and critical care medicine.
1997 Dec; 156(6):1846-54. doi:
10.1164/ajrccm.156.6.9701067. [PMID: 9412565] - M T Llinás, J D González, E Nava, F J Salazar. Role of angiotensin II in the renal effects induced by nitric oxide and prostaglandin synthesis inhibition.
Journal of the American Society of Nephrology : JASN.
1997 Apr; 8(4):543-50. doi:
. [PMID: 10495783] - A Mitra, S J Feinmark, P O Alderson. Thromboxane-mediated alveolar responses to acute obstruction of the pulmonary vasculature.
American journal of respiratory and critical care medicine.
1997 Mar; 155(3):978-83. doi:
10.1164/ajrccm.155.3.9117035. [PMID: 9117035] - M Jougasaki, L L Aarhus, D M Heublein, S M Sandberg, J C Burnett. Role of prostaglandins and renal nerves in the renal actions of adrenomedullin.
The American journal of physiology.
1997 Feb; 272(2 Pt 2):F260-6. doi:
10.1152/ajprenal.1997.272.2.f260. [PMID: 9124405] - S T Davidge, C A Hubel, M K McLaughlin. Impairment of vascular function is associated with an age-related increase of lipid peroxidation in rats.
The American journal of physiology.
1996 Dec; 271(6 Pt 2):R1625-31. doi:
10.1152/ajpregu.1996.271.6.r1625. [PMID: 8997362] - M R Taylor, S A Westwood, D Perrett. Determination of phase II drug metabolites in equine urine by micellar electrokinetic capillary chromatography.
Journal of chromatography. A.
1996 Sep; 745(1-2):155-63. doi:
10.1016/0021-9673(96)00380-9. [PMID: 8843684] - H Lin, M J Smith, D B Young. Roles of prostaglandins and nitric oxide in the effect of endothelin-1 on renal hemodynamics.
Hypertension (Dallas, Tex. : 1979).
1996 Sep; 28(3):372-8. doi:
10.1161/01.hyp.28.3.372. [PMID: 8794819] - J A Haas, F G Knox. Effect of meclofenamate or ketoconazole on the natriuretic response to increased pressure.
The Journal of laboratory and clinical medicine.
1996 Aug; 128(2):202-7. doi:
10.1016/s0022-2143(96)90012-8. [PMID: 8765216] - E A Galbraith, Q A McKellar. Protein binding and in vitro serum thromboxane B2 inhibition by flunixin meglumine and meclofenamic acid in dog, goat and horse blood.
Research in veterinary science.
1996 Jul; 61(1):78-81. doi:
10.1016/s0034-5288(96)90115-0. [PMID: 8819199] - K Schricker, A Kurtz. Blockade of nitric oxide formation inhibits the stimulation of the renin system by a low salt intake.
Pflugers Archiv : European journal of physiology.
1996 Jun; 432(2):187-91. doi:
10.1007/s004240050123. [PMID: 8662293] - T Encinas, E Vinagre, J C Boggio, M D San Andrés, C Rodríguez, M I San Andrés. Influence of closure of the reticular groove on the bioavailability and disposition kinetics of meclofenamate in sheep.
Journal of veterinary pharmacology and therapeutics.
1996 Feb; 19(1):15-21. doi:
10.1111/j.1365-2885.1996.tb00002.x. [PMID: 8992020] - R Munoz-Garcia, R Maeso, E Rodrigo, J Navarro, L M Ruilope, M C Casal, V Cachofeiro, V Lahera. Acute renal excretory actions of losartan in spontaneously hypertensive rats: role of AT2 receptors, prostaglandins, kinins and nitric oxide.
Journal of hypertension.
1995 Dec; 13(12 Pt 2):1779-84. doi:
. [PMID: 8903651] - C F Lim, N M Loidl, J A Kennedy, D J Topliss, J R Stokigt. Effect of loop diuretics and nonsteroidal antiinflammatory drugs on thyrotropin release by rat anterior pituitary cells in vitro.
Metabolism: clinical and experimental.
1995 Aug; 44(8):1008-12. doi:
10.1016/0026-0495(95)90097-7. [PMID: 7637641] - S Y Chou, J G Porush. Renal actions of endothelin-1 and endothelin-3: interactions with the prostaglandin system and nitric oxide.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
1995 Jul; 26(1):116-23. doi:
10.1016/0272-6386(95)90164-7. [PMID: 7541937] - F J Salazar, M T Llinas, J D Gonzalez, T Quesada, J M Pinilla. Role of prostaglandins and nitric oxide in mediating renal response to volume expansion.
The American journal of physiology.
1995 Jun; 268(6 Pt 2):R1442-8. doi:
10.1152/ajpregu.1995.268.6.r1442. [PMID: 7611520] - S Bochnowicz, D C Underwood. Dose-dependent mediation of leukotriene D4-induced airway microvascular leakage and bronchoconstriction in the guinea pig.
Prostaglandins, leukotrienes, and essential fatty acids.
1995 Jun; 52(6):403-11. doi:
10.1016/0952-3278(95)90069-1. [PMID: 7644563] - K Schricker, M Hamann, A Kurtz. Prostaglandins are involved in the stimulation of renin gene expression in 2 kidney-1 clip rats.
Pflugers Archiv : European journal of physiology.
1995 Jun; 430(2):188-94. doi:
10.1007/bf00374649. [PMID: 7675628] - J Greven, A Rahn, E Brändle. Effects of cicletanine on kidney function. 2. Role of renal prostaglandins and kinins, and of muscarinic receptors.
The Journal of pharmacology and experimental therapeutics.
1995 Jun; 273(3):1197-202. doi:
NULL. [PMID: 7791091] - T Encinas, E Vinagre, J C Boggio, M L de Vicente, M I San Andres, C Rodriguez. Comparison of the kinetics of sodium meclofenamate versus meclofenamic acid after oral administration to sheep.
Zentralblatt fur Veterinarmedizin. Reihe A.
1995 May; 42(3):177-83. doi:
10.1111/j.1439-0442.1995.tb00369.x. [PMID: 8578896] - R A Kramp, J Genard, P Fourmanoir, N Caron, G Laekeman, A Herman. Renal hemodynamics and blood flow autoregulation during acute cyclooxygenase inhibition in male rats.
The American journal of physiology.
1995 Mar; 268(3 Pt 2):F468-79. doi:
10.1152/ajprenal.1995.268.3.f468. [PMID: 7900847] - K Schricker, S Holmer, B K Krämer, G Riegger, A Kurtz. Control of renin gene expression in 2 kidney-1 clip rats.
Kidney international.
1994 Dec; 46(6):1539-41. doi:
10.1038/ki.1994.440. [PMID: 7700000] - K Schricker, M Hamann, B Kaissling, A Kurtz. Renal autacoids are involved in the stimulation of renin gene expression by low perfusion pressure.
Kidney international.
1994 Nov; 46(5):1330-6. doi:
10.1038/ki.1994.402. [PMID: 7853791] - J G Wood, Z Y Yan, L Y Cheung. Role of prostaglandins in angiotensin II-induced gastric vasoconstriction.
The American journal of physiology.
1994 Aug; 267(2 Pt 1):G173-9. doi:
10.1152/ajpgi.1994.267.2.g173. [PMID: 8074217] - R C Blantz, F B Gabbai, O Peterson, C B Wilson, I Kihara, H Kawachi, F Shimizu, T Yamamoto. Water and protein permeability is regulated by the glomerular epithelial slit diaphragm.
Journal of the American Society of Nephrology : JASN.
1994 Jun; 4(12):1957-64. doi:
10.1681/asn.v4121957. [PMID: 7919149] - A P Zou, J D Imig, P R Ortiz de Montellano, Z Sui, J R Falck, R J Roman. Effect of P-450 omega-hydroxylase metabolites of arachidonic acid on tubuloglomerular feedback.
The American journal of physiology.
1994 Jun; 266(6 Pt 2):F934-41. doi:
10.1152/ajprenal.1994.266.6.f934. [PMID: 8023972] - B A Stoos, O A Carretero, J L Garvin. Endothelial-derived nitric oxide inhibits sodium transport by affecting apical membrane channels in cultured collecting duct cells.
Journal of the American Society of Nephrology : JASN.
1994 May; 4(11):1855-60. doi:
10.1681/asn.v4111855. [PMID: 7919134] - P E Malo, R L Bell, T K Shaughnessy, J B Summers, D W Brooks, G W Carter. The 5-lipoxygenase inhibitory activity of zileuton in in vitro and in vivo models of antigen-induced airway anaphylaxis.
Pulmonary pharmacology.
1994 Apr; 7(2):73-9. doi:
10.1006/pulp.1994.1008. [PMID: 8081074] - L Hu, R D Manning, M W Brands. Long-term cardiovascular role of nitric oxide in conscious rats.
Hypertension (Dallas, Tex. : 1979).
1994 Feb; 23(2):185-94. doi:
10.1161/01.hyp.23.2.185. [PMID: 8307627] - D G Matsell, L W Gaber, K U Malik. Cytokine stimulation of prostaglandin production inhibits the proliferation of serum-stimulated mesangial cells.
Kidney international.
1994 Jan; 45(1):159-65. doi:
10.1038/ki.1994.19. [PMID: 8127005] - F J Martínez, E Villa, R García-Robles, J C Romero. Effect of nitric oxide and prostaglandins on renal function in insulin-resistant hypertensive dogs.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension.
1993 Dec; 11(5):S138-9. doi:
10.1097/00004872-199312050-00048. [PMID: 8158314] - M Fernandez-Rivas, B de la Hoz, M Cuevas, I Davila, S Quirce, E Losada. Hypersensitivity reactions to anthranilic acid derivatives.
Annals of allergy.
1993 Dec; 71(6):515-8. doi:
. [PMID: 7903514] - I Antonipillai, T H Le, L Soceneantu, R Horton. Transforming growth factor-beta is a renin secretagogue at picomolar concentrations.
The American journal of physiology.
1993 Oct; 265(4 Pt 2):F537-41. doi:
10.1152/ajprenal.1993.265.4.f537. [PMID: 8238382] - T E Rayner, B N Chen, J W McLoughlin, M F Menadue, R J Norman, J R Oliver. Prostaglandin F2 alpha mediates platelet-activating factor-stimulated atrial natriuretic factor release from the isolated rat heart.
Endocrinology.
1993 Sep; 133(3):1108-15. doi:
10.1210/endo.133.3.8365356. [PMID: 8365356] - S T Davidge, C A Hubel, M K McLaughlin. Cyclooxygenase-dependent vasoconstrictor alters vascular function in the vitamin E-deprived rat.
Circulation research.
1993 Jul; 73(1):79-88. doi:
10.1161/01.res.73.1.79. [PMID: 8508535] - K Uzuner, R O Banks. Endothelin-induced natriuresis and diuresis are pressure-dependent events in the rat.
The American journal of physiology.
1993 Jul; 265(1 Pt 2):R90-6. doi:
10.1152/ajpregu.1993.265.1.r90. [PMID: 8342702] - K Yamaguchi, H Hama. Evaluation for roles of brain prostaglandins in the catecholamine-induced vasopressin secretion in conscious rats.
Brain research.
1993 Apr; 607(1-2):149-53. doi:
10.1016/0006-8993(93)91500-r. [PMID: 8386972] - W H Boer, R Fransen, P Boer, R de Roos, H A Koomans. Prostaglandin synthesis inhibition stimulates lithium reabsorption in Henle's loop in rats.
Kidney international.
1993 Feb; 43(2):301-6. doi:
10.1038/ki.1993.47. [PMID: 8441226] - D T Pals, S J Couch. Renin release induced by losartan (DuP 753), an angiotensin II receptor antagonist.
Clinical and experimental hypertension (New York, N.Y. : 1993).
1993 Jan; 15(1):1-13. doi:
10.3109/10641969309041609. [PMID: 8385523] - S Zacharieva, M Wippermann, I Muchá, K Andonova, G Jankova. Indomethacin and meclofenamate do not alter ACTH and cortisol responses to corticotropin-releasing hormone (CRH) in normal subjects.
Clinical physiology and biochemistry.
1993; 10(1):28-32. doi:
. [PMID: 8393395] - M Banerjee, K H Kang, J D Morrow, L J Roberts, J H Newman. Effects of a novel prostaglandin, 8-epi-PGF2 alpha, in rabbit lung in situ.
The American journal of physiology.
1992 Sep; 263(3 Pt 2):H660-3. doi:
10.1152/ajpheart.1992.263.3.h660. [PMID: 1415588] - S Zacharieva, A M Borissova, J Popova, K Andonova. Role of prostaglandin E2 (PGE2) in the growth hormone releasing hormone action on growth hormone, insulin and C-peptide in normal men.
Diabete & metabolisme.
1992 May; 18(3):202-8. doi:
. [PMID: 1397474] - M L Kauker, E T Zawada. Post-obstruction diuresis: influence of renal prostaglandins.
Nephron.
1992; 60(3):281-5. doi:
10.1159/000186766. [PMID: 1565180] - J P Granger, A M Alberola, F J Salazar, T Nakamura. Control of renal hemodynamics during intrarenal and systemic blockade of nitric oxide synthesis in conscious dogs.
Journal of cardiovascular pharmacology.
1992; 20 Suppl 12(?):S160-2. doi:
10.1097/00005344-199204002-00045. [PMID: 1282957] - U C Kopp, L A Smith. Inhibitory renorenal reflexes: a role for renal prostaglandins in activation of renal sensory receptors.
The American journal of physiology.
1991 Dec; 261(6 Pt 2):R1513-21. doi:
10.1152/ajpregu.1991.261.6.r1513. [PMID: 1750575] - C F Lim, A J Curtis, J W Barlow, D J Topliss, J R Stockigt. Interactions between oleic acid and drug competitors influence specific binding of thyroxine in serum.
The Journal of clinical endocrinology and metabolism.
1991 Nov; 73(5):1106-10. doi:
10.1210/jcem-73-5-1106. [PMID: 1939526] - D R Morel, M Skoskiewicz, D R Robinson, K J Bloch, D C Hoaglin, W M Zapol. Leukotrienes, thromboxane A2, and prostaglandins during systemic anaphylaxis in sheep.
The American journal of physiology.
1991 Sep; 261(3 Pt 2):H782-92. doi:
10.1152/ajpheart.1991.261.3.h782. [PMID: 1716064] - I M Johansson, P Kallings, M Hammarlund-Udenaes. Studies of meclofenamic acid and two metabolites in horses--pharmacokinetics and effects on exercise tolerance.
Journal of veterinary pharmacology and therapeutics.
1991 Sep; 14(3):235-42. doi:
10.1111/j.1365-2885.1991.tb00832.x. [PMID: 1744932] - J Greven. Attenuation of azosemide's action in the loop of Henle of rat kidney by nonsteroidal anti-inflammatory drugs.
Arzneimittel-Forschung.
1991 Aug; 41(8):805-8. doi:
NULL. [PMID: 1781802] - A Hishida, K Ohishi, R Furuya, A Katoh, N Honda. Direct action of vasoactive substances on isolated canine superficial and juxtamedullary afferent arterioles.
Kidney international. Supplement.
1991 Jun; 32(?):S86-8. doi:
NULL. [PMID: 1881059] - M J Fiksen-Olsen, J C Romero. Renal effects of prostaglandin inhibition during increases in renal venous pressure.
The American journal of physiology.
1991 Apr; 260(4 Pt 2):F525-9. doi:
10.1152/ajprenal.1991.260.4.f525. [PMID: 2012205] - M Martí-Cabrera, J L Ortiz, J M Durá, J Cortijo, M D Barrachina, E Morcillo. Differential effects of cyclooxygenase inhibitors on the cardiovascular response to hyperosmotic mannitol.
Methods and findings in experimental and clinical pharmacology.
1991 Apr; 13(3):175-9. doi:
NULL. [PMID: 1904968] - R F Regester, M H Goldman. Meclofenamate treatment of posttransplant nephrotic syndrome.
Transplantation proceedings.
1991 Apr; 23(2):1789-90. doi:
NULL. [PMID: 2053156] - I H Zucker, J S Chen, W Wang. Renal sympathetic nerve and hemodynamic responses to captopril in conscious dogs: role of prostaglandins.
The American journal of physiology.
1991 Jan; 260(1 Pt 2):H260-6. doi:
10.1152/ajpheart.1991.260.1.h260. [PMID: 1899541] - G L Larsen, D M Presley, J P Graves, P C Giclas. The effect of intravascular complement activation and brief episodes of hypoxia on protein in bronchoalveolar lavage fluid in C5 sufficient and deficient mice.
Pediatric pulmonology.
1991; 11(4):302-9. doi:
10.1002/ppul.1950110406. [PMID: 1758754] - M C Conroy, E J Randinitis, J L Turner. Pharmacology, pharmacokinetics, and therapeutic use of meclofenamate sodium.
The Clinical journal of pain.
1991; 7 Suppl 1(?):S44-8. doi:
. [PMID: 1810520] - F Facchinetti, R De Pietri, M Giunchi, A R Genazzani. Use of meclofenamic acid in gynecology and obstetrics: effects on postsurgical stress.
The Clinical journal of pain.
1991; 7 Suppl 1(?):S60-3. doi:
. [PMID: 1810523] - J D Barber, N G Moss. Reduced renal perfusion pressure causes prostaglandin-dependent excitation of R2 chemoreceptors in rats.
The American journal of physiology.
1990 Dec; 259(6 Pt 2):R1243-9. doi:
10.1152/ajpregu.1990.259.6.r1243. [PMID: 2260734] - R Hui, P Falardeau. Resistance of the renal biosynthesis of prostaglandin E2 to the inhibitory effect of indomethacin in the rat in vivo.
Prostaglandins, leukotrienes, and essential fatty acids.
1990 Oct; 41(2):83-7. doi:
10.1016/0952-3278(90)90058-s. [PMID: 2274569] - E S Mitchell, Q A McKellar, J A Bogan. Effect of meclofenamic acid on the response of parasite-naive lambs and adult sheep to Ostertagia circumcincta.
Research in veterinary science.
1990 Sep; 49(2):166-70. doi:
NULL. [PMID: 2236912] - G R Nakamura, R D Meeks, W J Stall. Solid-phase extraction, identification, and quantitation of 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid.
Journal of forensic sciences.
1990 Jul; 35(4):792-6. doi:
NULL. [PMID: 2167920] - V Lahera, M G Salom, M J Fiksen-Olsen, L Raij, J C Romero. Effects of NG-monomethyl-L-arginine and L-arginine on acetylcholine renal response.
Hypertension (Dallas, Tex. : 1979).
1990 Jun; 15(6 Pt 1):659-63. doi:
10.1161/01.hyp.15.6.659. [PMID: 2347626]