Chlortoluron (BioDeep_00000015017)

   

natural product Industrial Pollutants


代谢物信息卡片


Pesticide3_Chlorotoluron_C10H13ClN2O_Urea, N-(3-chloro-4-methylphenyl)-N,N-dimethyl-

化学式: C10H13ClN2O (212.0716)
中文名称: 乙腈中绿麦隆溶液, 氯酯脲
谱图信息: 最多检出来源 Viridiplantae(plant) 4.56%

分子结构信息

SMILES: c1(c(ccc(c1)NC(N(C)C)=O)C)Cl
InChI: InChI=1S/C10H13ClN2O/c1-7-4-5-8(6-9(7)11)12-10(14)13(2)3/h4-6H,1-3H3,(H,12,14)

描述信息

D010575 - Pesticides > D006540 - Herbicides
D016573 - Agrochemicals
CONFIDENCE standard compound; EAWAG_UCHEM_ID 273
CONFIDENCE standard compound; INTERNAL_ID 2314
CONFIDENCE standard compound; INTERNAL_ID 8382
CONFIDENCE standard compound; INTERNAL_ID 4007

同义名列表

5 个代谢物同义名

Chlorotoluron; Chlortoluron; Pesticide3_Chlorotoluron_C10H13ClN2O_Urea, N-(3-chloro-4-methylphenyl)-N,N-dimethyl-; CLL; Chlorotoluron



数据库引用编号

42 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Keiko Gion, Hideyuki Inui, Kazuyuki Takakuma, Takashi Yamada, Yumiko Kambara, Shuichi Nakai, Hiroyuki Fujiwara, Takashi Miyamura, Hiromasa Imaishi, Hideo Ohkawa. Molecular mechanisms of herbicide-inducible gene expression of tobacco CYP71AH11 metabolizing the herbicide chlorotoluron. Pesticide biochemistry and physiology. 2014 Jan; 108(?):49-57. doi: 10.1016/j.pestbp.2013.12.003. [PMID: 24485315]
  • Rashad Kebeish, Ehab Azab, Christoph Peterhaensel, Radwa El-Basheer. Engineering the metabolism of the phenylurea herbicide chlortoluron in genetically modified Arabidopsis thaliana plants expressing the mammalian cytochrome P450 enzyme CYP1A2. Environmental science and pollution research international. 2014; 21(13):8224-32. doi: 10.1007/s11356-014-2710-5. [PMID: 24920432]
  • Qinfan Li, Yupeng Fang, Xiuxiu Li, Hong Zhang, Mengmeng Liu, Huibin Yang, Zhuo Kang, Yan Li, Yonghua Wang. Mechanism of the plant cytochrome P450 for herbicide resistance: a modelling study. Journal of enzyme inhibition and medicinal chemistry. 2013 Dec; 28(6):1182-91. doi: 10.3109/14756366.2012.719505. [PMID: 23057845]
  • Amornrat Phongdara, Alisa Nakkaew, Sureeporn Nualkaew. Isolation of the detoxification enzyme EgP450 from an oil palm EST library. Pharmaceutical biology. 2012 Jan; 50(1):120-7. doi: 10.3109/13880209.2011.631019. [PMID: 22196587]
  • Fabiola G Zuno-Floriano, Marion G Miller, Maria L Aldana-Madrid, Matt J Hengel, Nilesh W Gaikwad, Vladimir Tolstikov, Ana G Contreras-Cortés. Effect of Acinetobacter sp on metalaxyl degradation and metabolite profile of potato seedlings (Solanum tuberosum L.) alpha variety. PloS one. 2012; 7(2):e31221. doi: 10.1371/journal.pone.0031221. [PMID: 22363586]
  • Thomas Hartwig, Claudia Corvalan, Norman B Best, Joshua S Budka, Jia-Ying Zhu, Sunghwa Choe, Burkhard Schulz. Propiconazole is a specific and accessible brassinosteroid (BR) biosynthesis inhibitor for Arabidopsis and maize. PloS one. 2012; 7(5):e36625. doi: 10.1371/journal.pone.0036625. [PMID: 22590578]
  • Xueyuan Li, Lu Wang, Ziming Wang, Huihui Zhang, Rui Su, Xu Xu, Hanqi Zhang. Ultrasonic nebulization extraction coupled with headspace hollow fiber microextraction of pesticides from root of Panax ginseng C.A. Mey. Journal of separation science. 2011 Jul; 34(13):1582-9. doi: 10.1002/jssc.201000858. [PMID: 21626693]
  • Kasturi Dasgupta, Savita Ganesan, Sindhu Manivasagam, Brian G Ayre. A cytochrome P450 monooxygenase commonly used for negative selection in transgenic plants causes growth anomalies by disrupting brassinosteroid signaling. BMC plant biology. 2011 Apr; 11(?):67. doi: 10.1186/1471-2229-11-67. [PMID: 21496250]
  • Eliseo Herrero-Hernández, Rita Carabias-Martínez, Encarnacion Rodríguez-Gonzalo. Behavior of phenols and phenoxyacids on a bisphenol-A imprinted polymer. Application for selective solid-phase extraction from water and urine samples. International journal of molecular sciences. 2011; 12(5):3322-39. doi: 10.3390/ijms12053322. [PMID: 21686187]
  • Ning Hui Song, Shuang Zhang, Min Hong, Hong Yang. Impact of dissolved organic matter on bioavailability of chlorotoluron to wheat. Environmental pollution (Barking, Essex : 1987). 2010 Mar; 158(3):906-12. doi: 10.1016/j.envpol.2009.09.019. [PMID: 19819600]
  • S López-Feria, S Cárdenas, M Valcárcel. One step carbon nanotubes-based solid-phase extraction for the gas chromatographic-mass spectrometric multiclass pesticide control in virgin olive oils. Journal of chromatography. A. 2009 Oct; 1216(43):7346-50. doi: 10.1016/j.chroma.2009.02.060. [PMID: 19298965]
  • Ning Hui Song, Xiao Le Yin, Guo Feng Chen, Hong Yang. Biological responses of wheat (Triticum aestivum) plants to the herbicide chlorotoluron in soils. Chemosphere. 2007 Aug; 68(9):1779-87. doi: 10.1016/j.chemosphere.2007.03.023. [PMID: 17462703]
  • Yaron Drori, Buuan Lam, Andre Simpson, Zeev Aizenshtat, Benny Chefetz. The role of lipids on sorption characteristics of freshwater- and wastewater-irrigated soils. Journal of environmental quality. 2006 Nov; 35(6):2154-61. doi: 10.2134/jeq2006.0013. [PMID: 17071884]
  • Ning-Hui Song, Zhi-Min Yang, Li-Xian Zhou, Xin Wu, Hong Yang. Effect of dissolved organic matter on the toxicity of chlorotoluron to Triticum aestivum. Journal of environmental sciences (China). 2006; 18(1):101-8. doi: ". [PMID: 20050556]
  • Hiroyuki Kawahigashi, Sakiko Hirose, Kenjirou Ozawa, Yoshiko Ido, Misaki Kojima, Hideo Ohkawa, Yasunobu Ohkawa. Analysis of substrate specificity of pig CYP2B22 and CYP2C49 towards herbicides by transgenic rice plants. Transgenic research. 2005 Dec; 14(6):907-17. doi: 10.1007/s11248-005-0199-x. [PMID: 16315095]
  • Sakiko Hirose, Hiroyuki Kawahigashi, Kenjirou Ozawa, Noriaki Shiota, Hideyuki Inui, Hideo Ohkawa, Yasunobu Ohkawa. Transgenic rice containing human CYP2B6 detoxifies various classes of herbicides. Journal of agricultural and food chemistry. 2005 May; 53(9):3461-7. doi: 10.1021/jf050064z. [PMID: 15853388]
  • F G Tamayo, J L Casillas, A Martin-Esteban. Clean up of phenylurea herbicides in plant sample extracts using molecularly imprinted polymers. Analytical and bioanalytical chemistry. 2005 Mar; 381(6):1234-40. doi: 10.1007/s00216-005-3071-1. [PMID: 15756601]
  • Stephen R Moss, Kay M Cocker, Amanda C Brown, Linda Hall, Linda M Field. Characterisation of target-site resistance to ACCase-inhibiting herbicides in the weed Alopecurus myosuroides (black-grass). Pest management science. 2003 Feb; 59(2):190-201. doi: 10.1002/ps.623. [PMID: 12587873]
  • Luc Didierjean, Laurence Gondet, Roberta Perkins, Sze-Mei Cindy Lau, Hubert Schaller, Daniel P O'Keefe, Danièle Werck-Reichhart. Engineering herbicide metabolism in tobacco and Arabidopsis with CYP76B1, a cytochrome P450 enzyme from Jerusalem artichoke. Plant physiology. 2002 Sep; 130(1):179-89. doi: 10.1104/pp.005801. [PMID: 12226498]
  • T. Yamada, T. Ishige, N. Shiota, H. Inui, H. Ohkawa, Y. Ohkawa. Enhancement of metabolizing herbicides in young tubers of transgenic potato plants with the rat CYP1A1 gene. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik. 2002 Sep; 105(4):515-520. doi: 10.1007/s00122-002-0961-x. [PMID: 12582499]
  • T Lacour, H Ohkawa. Engineering and biochemical characterization of the rat microsomal cytochrome P4501A1 fused to ferredoxin and ferredoxin-NADP(+) reductase from plant chloroplasts. Biochimica et biophysica acta. 1999 Aug; 1433(1-2):87-102. doi: 10.1016/s0167-4838(99)00154-5. [PMID: 10446362]
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  • M F Katmeh, G W Aherne, D Stevenson. Competitive enzyme-linked immunosorbent assay for the determination of the phenylurea herbicide chlortoluron in water and biological fluids. The Analyst. 1996 Nov; 121(11):1699-703. doi: 10.1039/an9962101699. [PMID: 8952458]
  • U Tröhler, J P Bonjour, H Fleisch. Inorganic phosphate homeostasis. Renal adaptation to the dietary intake in intact and thyroparathyroidectomized rats. The Journal of clinical investigation. 1976 Feb; 57(2):264-73. doi: 10.1172/jci108277. [PMID: 3518]