Acebutolol HCl (BioDeep_00000015009)
natural product Volatile Flavor Compounds
代谢物信息卡片
Acebutolol hydrochloride
化学式: C18H29ClN2O4 (372.18157440000004)
中文名称: 盐酸醋丁洛尔
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1(=C(C=C(C=C1)NC(CCC)=O)C(C)=O)OCC(CNC(C)C)O.Cl
InChI: 1H
描述信息
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents
Acebutolol hydrochloride is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol hydrochloride is used in the treatment of hypertension, angina pectoris and cardiac arrhythmias[1][2][3].
同义名列表
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:2380
- KEGG: C07677
- KEGGdrug: D00597
- PubChem: 441307
- ChEMBL: CHEMBL1200813
- MeSH: Acebutolol
- CAS: 34381-68-5
- CAS: 34381-68-5, 37517-30-9 (free base)
- MoNA: CCMSLIB00000078619
- PubChem: 9879
- NIKKAJI: J365.005G
- RefMet: Acebutolol hydrochloride
- medchemexpress: HY-17497A
- KNApSAcK: 2380
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- E Bokri, H Felfel, S Bahri. Prediction of plasma concentrations using in silico modelling and simulation approach: Case of Acebutolol.
Annales pharmaceutiques francaises.
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1990; 16 Suppl 5(?):S179-83. doi:
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Indian heart journal.
1989 Sep; 41(5):292-5. doi:
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Acta poloniae pharmaceutica.
1989; 46(4):350-3. doi:
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Japanese journal of medicine.
1989 Jan; 28(1):8-15. doi:
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Circulation.
1988 Oct; 78(4):957-68. doi:
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International journal of clinical pharmacology, therapy, and toxicology.
1988 Oct; 26(10):513-6. doi:
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Journal of hypertension.
1988 Jul; 6(7):579-85. doi:
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Endocrinologia japonica.
1988 Jun; 35(3):485-90. doi:
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Archives francaises de pediatrie.
1988 Apr; 45(4):287-94. doi:
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Fortschritte der Medizin.
1988 Feb; 106(6):118-22. doi:
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Der Anaesthesist.
1988 Feb; 37(2):77-83. doi:
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Drugs.
1988; 36 Suppl 2(?):41-50. doi:
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Psychopharmacology.
1988; 95(2):245-9. doi:
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Acta medica Scandinavica.
1988; 223(4):305-11. doi:
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European journal of clinical pharmacology.
1988; 34(2):125-8. doi:
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Drugs.
1988; 36 Suppl 2(?):51-6. doi:
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American heart journal.
1987 Oct; 114(4 Pt 2):1007-10. doi:
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Revista medica de Chile.
1987 Sep; 115(9):836-41. doi:
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Hypertension (Dallas, Tex. : 1979).
1987 Aug; 10(2):221-5. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
1987 Mar; 17(3):255-65. doi:
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Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.
1987; 87(1):83-6. doi:
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Clinical pharmacology and therapeutics.
1987 Jan; 41(1):45-54. doi:
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Acta medica Scandinavica.
1987; 222(2):143-6. doi:
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Biochemical pharmacology.
1986 Dec; 35(24):4579-81. doi:
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Cardiovascular research.
1986 Oct; 20(10):721-6. doi:
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Jikken dobutsu. Experimental animals.
1986 Oct; 35(4):367-73. doi:
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Journal of endocrinological investigation.
1986 Oct; 9(5):413-5. doi:
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The Journal of pharmacy and pharmacology.
1986 Sep; 38(9):699-702. doi:
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The Journal of pharmacology and experimental therapeutics.
1986 Jul; 238(1):378-87. doi:
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Clinical pharmacology and therapeutics.
1986 Apr; 39(4):361-8. doi:
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