Econazole nitrate (BioDeep_00000015001)
代谢物信息卡片
Econazole (nitrate)
化学式: C18H16Cl3N3O4 (443.02063460000005)
中文名称: 硝酸益康唑
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-]
InChI: (H,2,3,4)
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D065088 - Steroid Synthesis Inhibitors
D004791 - Enzyme Inhibitors > D065088 - Steroid Synthesis Inhibitors > D058888 - 14-alpha Demethylase Inhibitors
D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
C254 - Anti-Infective Agent > C514 - Antifungal Agent
同义名列表
3 个代谢物同义名
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:4755
- KEGG: C08069
- KEGGdrug: D00881
- PubChem: 68589
- ChEMBL: CHEMBL1201049
- MeSH: Econazole
- CAS: 24169-02-6
- CAS: 68797-31-9
- PubChem: 10269
- NIKKAJI: J244.551D
- RefMet: Econazole nitrate
- KNApSAcK: 4755
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Zhen Liang, Zhen Zhang, Ping Lu, Jingjing Yang, Lei Han, Susu Liu, Tianyang Zhou, Jingguo Li, Junjie Zhang. The effect of charges on the corneal penetration of solid lipid nanoparticles loaded Econazole after topical administration in rabbits.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2023 Aug; 187(?):106494. doi:
10.1016/j.ejps.2023.106494. [PMID: 37315870] - Qiong Li, Siyuan Qin, Hailong Tian, Ruolan Liu, Ling Qiao, Shanshan Liu, Bowen Li, Mei Yang, Jiayan Shi, Edouard C Nice, Jingquan Li, Tingyuan Lang, Canhua Huang. Nano-Econazole Enhanced PD-L1 Checkpoint Blockade for Synergistic Antitumor Immunotherapy against Pancreatic Ductal Adenocarcinoma.
Small (Weinheim an der Bergstrasse, Germany).
2023 Mar; ?(?):e2207201. doi:
10.1002/smll.202207201. [PMID: 36899444] - Arthur Neuberger, Kirill D Nadezhdin, Alexander I Sobolevsky. Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole.
Nature communications.
2021 11; 12(1):6284. doi:
10.1038/s41467-021-26608-x. [PMID: 34725357] - Junyuan Zhang, Beibei Liu, Zhen Jiang, Yan Cui, Xingjie Guo. Enantioselective determination of econazole in rat plasma and its application to a pharmacokinetic study.
Analytical biochemistry.
2020 08; 602(?):113791. doi:
10.1016/j.ab.2020.113791. [PMID: 32473119] - A F D Di Stefano, M M Radicioni, A Vaccani, G Caccia, F Focanti, E Salvatori, F Pelacchi, R Picollo, M T Rosignoli, S Olivieri, G Bovi, A Comandini. Phase I Study in Healthy Women of a Novel Antimycotic Vaginal Ovule Combining Econazole and Benzydamine.
Infectious diseases in obstetrics and gynecology.
2020; 2020(?):7201840. doi:
10.1155/2020/7201840. [PMID: 32410819] - Young-Guk Na, Hyun Wook Huh, Min-Ki Kim, Jin-Ju Byeon, Min-Gu Han, Hong-Ki Lee, Cheong-Weon Cho. Development and evaluation of a film-forming system hybridized with econazole-loaded nanostructured lipid carriers for enhanced antifungal activity against dermatophytes.
Acta biomaterialia.
2020 01; 101(?):507-518. doi:
10.1016/j.actbio.2019.10.024. [PMID: 31629894] - Luisa S Dolci, Anna Liguori, Silvia Panzavolta, Anna Miserocchi, Nadia Passerini, Matteo Gherardi, Vittorio Colombo, Adriana Bigi, Beatrice Albertini. Non-equilibrium atmospheric pressure plasma as innovative method to crosslink and enhance mucoadhesion of econazole-loaded gelatin films for buccal drug delivery.
Colloids and surfaces. B, Biointerfaces.
2018 Mar; 163(?):73-82. doi:
10.1016/j.colsurfb.2017.12.030. [PMID: 29278802] - Taylor E T Hughes, David T Lodowski, Kevin W Huynh, Aysenur Yazici, John Del Rosario, Abhijeet Kapoor, Sandip Basak, Amrita Samanta, Xu Han, Sudha Chakrapani, Z Hong Zhou, Marta Filizola, Tibor Rohacs, Seungil Han, Vera Y Moiseenkova-Bell. Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.
Nature structural & molecular biology.
2018 01; 25(1):53-60. doi:
10.1038/s41594-017-0009-1. [PMID: 29323279] - Rohan M Shah, Daniel S Eldridge, Enzo A Palombo, Ian H Harding. Microwave-assisted microemulsion technique for production of miconazole nitrate- and econazole nitrate-loaded solid lipid nanoparticles.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2017 Aug; 117(?):141-150. doi:
10.1016/j.ejpb.2017.04.007. [PMID: 28411057] - Yongjing Liu, Miaoduo Deng, Jia Yu, Zhen Jiang, Xingjie Guo. Capillary electrophoretic enantioseparation of basic drugs using a new single-isomer cyclodextrin derivative and theoretical study of the chiral recognition mechanism.
Journal of separation science.
2016 May; 39(9):1766-75. doi:
10.1002/jssc.201501026. [PMID: 26935589] - Mirza Akram Hossain, Augustine Lalloz, Aicha Benhaddou, Fabrice Pagniez, Martine Raymond, Patrice Le Pape, Pierre Simard, Karine Théberge, Jeanne Leblond. Econazole imprinted textiles with antifungal activity.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2016 Apr; 101(?):137-44. doi:
10.1016/j.ejpb.2016.02.003. [PMID: 26883854] - Zheqin Hu, Juan Zhang, Xiangrong Cheng. Antifungal efficiency of miconazole and econazole and the interaction with transport protein: a comparative study.
Pharmaceutical biology.
2015 Feb; 53(2):251-61. doi:
10.3109/13880209.2014.914232. [PMID: 25376919] - Juliana Tonini Mesquita, Thais Alves da Costa-Silva, Samanta Etel Treiger Borborema, André Gustavo Tempone. Activity of imidazole compounds on Leishmania (L.) infantum chagasi: reactive oxygen species induced by econazole.
Molecular and cellular biochemistry.
2014 Apr; 389(1-2):293-300. doi:
10.1007/s11010-013-1954-6. [PMID: 24374794] - Lav Keshri, Kamla Pathak. Development of thermodynamically stable nanostructured lipid carrier system using central composite design for zero order permeation of econazole nitrate through epidermis.
Pharmaceutical development and technology.
2013 May; 18(3):634-44. doi:
10.3109/10837450.2012.659256. [PMID: 22339250] - I S Chen, K T Mok, C T Chou, S I Liu, C C Kuo, S S Hsu, H T Chang, J Y Tsai, W C Liao, C R Jan. Effect of phenethyl isothiocyanate on Ca2+ movement and viability in MDCK canine renal tubular cells.
Human & experimental toxicology.
2012 Dec; 31(12):1251-61. doi:
10.1177/0960327112446841. [PMID: 22653687] - He-Hsiung Cheng, Yi-Chau Lu, Ti Lu, Jin-Shiung Cheng, Guang-Yuan Mar, Yi-Chien Fang, Kuo-Liang Chai, Chung-Ren Jan. Effect of methoxychlor on Ca(2+) movement and viability in MDCK renal tubular cells.
Basic & clinical pharmacology & toxicology.
2012 Oct; 111(4):224-31. doi:
10.1111/j.1742-7843.2012.00887.x. [PMID: 22458924] - S Li, Y Q Qiu, S H Zhang, Y H Gao. A novel transdermal fomulation of 18β-glycyrrhetic acid with lysine for improving bioavailability and efficacy.
Skin pharmacology and physiology.
2012; 25(5):257-68. doi:
10.1159/000339652. [PMID: 22832704] - P Agretti, A Dimida, G De Marco, E Ferrarini, J C Rodrìguez Gonzàlez, F Santini, P Vitti, A Pinchera, M Tonacchera. Study of potential inhibitors of thyroid iodide uptake by using CHO cells stably expressing the human sodium/iodide symporter (hNIS) protein.
Journal of endocrinological investigation.
2011 Mar; 34(3):170-4. doi:
10.1007/bf03347061. [PMID: 20479570] - Yongmao Yu, Yicheng Zhang, Ziping Zhu, Stuart A Berger. ABC50 modulates sensitivity of HL60 leukemic cells to endoplasmic reticulum (ER) stress-induced cell death.
Biochemical pharmacology.
2011 Feb; 81(4):488-97. doi:
10.1016/j.bcp.2010.11.007. [PMID: 21087599] - Christopher P Landowski, Katrin A Bolanz, Yoshiro Suzuki, Matthias A Hediger. Chemical inhibitors of the calcium entry channel TRPV6.
Pharmaceutical research.
2011 Feb; 28(2):322-30. doi:
10.1007/s11095-010-0249-9. [PMID: 21057859] - Vanna Sanna, Alberto Mariani, Giuseppe Caria, Mario Sechi. Synthesis and evaluation of different fatty acid esters formulated into Precirol ATO-Based lipid nanoparticles as vehicles for topical delivery.
Chemical & pharmaceutical bulletin.
2009 Jul; 57(7):680-4. doi:
10.1248/cpb.57.680. [PMID: 19571411] - Akio Kinazaki, Yoko Sakanashi, Tomohiro M Oyama, Haruka Shibagaki, Kohei Yamashita, Erika Hashimoto, Yumiko Nishimura, Shiro Ishida, Yoshiro Okano, Yasuo Oyama. Micromolar Zn(2+) potentiates the cytotoxic action of submicromolar econazole in rat thymocytes: possible disturbance of intracellular Ca(2+) and Zn(2+) homeostasis.
Toxicology in vitro : an international journal published in association with BIBRA.
2009 Jun; 23(4):610-6. doi:
10.1016/j.tiv.2009.02.001. [PMID: 19490836] - Nadia Passerini, Elisabetta Gavini, Beatrice Albertini, Giovanna Rassu, Marcello Di Sabatino, Vanna Sanna, Paolo Giunchedi, Lorenzo Rodriguez. Evaluation of solid lipid microparticles produced by spray congealing for topical application of econazole nitrate.
The Journal of pharmacy and pharmacology.
2009 May; 61(5):559-67. doi:
10.1211/jpp/61.05.0003. [PMID: 19405993] - Beatrice Albertini, Nadia Passerini, Marcello Di Sabatino, Beatrice Vitali, Patrizia Brigidi, Lorenzo Rodriguez. Polymer-lipid based mucoadhesive microspheres prepared by spray-congealing for the vaginal delivery of econazole nitrate.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2009 Mar; 36(4-5):591-601. doi:
10.1016/j.ejps.2008.12.009. [PMID: 19150403] - Zahoor Ahmad, Rajesh Pandey, Sadhna Sharma, G K Khuller. Novel chemotherapy for tuberculosis: chemotherapeutic potential of econazole- and moxifloxacin-loaded PLG nanoparticles.
International journal of antimicrobial agents.
2008 Feb; 31(2):142-6. doi:
10.1016/j.ijantimicag.2007.10.017. [PMID: 18155883] - Vanna Sanna, Elisabetta Gavini, Massimo Cossu, Giovanna Rassu, Paolo Giunchedi. Solid lipid nanoparticles (SLN) as carriers for the topical delivery of econazole nitrate: in-vitro characterization, ex-vivo and in-vivo studies.
The Journal of pharmacy and pharmacology.
2007 Aug; 59(8):1057-64. doi:
10.1211/jpp.59.8.0002. [PMID: 17725847] - Sebastian Cogswell, Stuart Berger, Dawn Waterhouse, Marcel B Bally, Ellen K Wasan. A parenteral econazole formulation using a novel micelle-to-liposome transfer method: in vitro characterization and tumor growth delay in a breast cancer xenograft model.
Pharmaceutical research.
2006 Nov; 23(11):2575-85. doi:
10.1007/pl00022054. [PMID: 17086505] - Rajesh Pandey, Zahoor Ahmad, Sadhna Sharma, G K Khuller. Nano-encapsulation of azole antifungals: potential applications to improve oral drug delivery.
International journal of pharmaceutics.
2005 Sep; 301(1-2):268-76. doi:
10.1016/j.ijpharm.2005.05.027. [PMID: 16023808] - K Hill, S McNulty, A D Randall. Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole.
Naunyn-Schmiedeberg's archives of pharmacology.
2004 Oct; 370(4):227-37. doi:
10.1007/s00210-004-0981-y. [PMID: 15549272] - Chi-Feng Liu, Chia-Hsien Lin, Chun-Ching Lin, Yun-Ho Lin, Chin-Fa Chen, Chao-Kuang Lin, Song-Chow Lin. Antioxidative natural product protect against econazole-induced liver injuries.
Toxicology.
2004 Mar; 196(1-2):87-93. doi:
10.1016/j.tox.2003.11.007. [PMID: 15036759] - Jonathan Soboloff, Yicheng Zhang, Mark Minden, Stuart A Berger. Sensitivity of myeloid leukemia cells to calcium influx blockade: application to bone marrow purging.
Experimental hematology.
2002 Oct; 30(10):1219-26. doi:
10.1016/s0301-472x(02)00893-7. [PMID: 12384154] - Chi-Feng Liu, Chun-Ching Lin, Lean-Teik Ng, Song-Chow Lin. Hepatoprotective and therapeutic effects of tetramethylpyrazine on acute econazole-induced liver injury.
Planta medica.
2002 Jun; 68(6):510-4. doi:
10.1055/s-2002-32569. [PMID: 12094293] - P Chiap, Ph Hubert, J Crommen. Strategy for the development of automated methods involving dialysis and trace enrichment as on-line sample preparation for the determination of basic drugs in plasma by liquid chromatography.
Journal of chromatography. A.
2002 Mar; 948(1-2):151-61. doi:
10.1016/s0021-9673(01)01318-8. [PMID: 12831192] - B Tunçtan, S Altuğ, O Uludağ, N Abacioğlu. Effects of econazole on receptor-operated and depolarization-induced contractions in rat isolated aorta.
Life sciences.
2000 Sep; 67(19):2393-401. doi:
10.1016/s0024-3205(00)00822-5. [PMID: 11065186] - S Jenner, S O Sage. Two pathways for store-mediated calcium entry in human platelets.
Platelets.
2000 Jun; 11(4):215-21. doi:
10.1080/09537100050057657. [PMID: 10938900] - I Benko, F Hernádi, A Megyeri, A Kiss, G Somogyi, Z Tegyey, F Kraicsovits, P Kovács. Comparison of the toxicity of fluconazole and other azole antifungal drugs to murine and human granulocyte-macrophage progenitor cells in vitro.
The Journal of antimicrobial chemotherapy.
1999 May; 43(5):675-81. doi:
10.1093/jac/43.5.675. [PMID: 10382889] - C R Jan, S N Wu, C J Tseng. A further investigation of ATP-induced calcium mobilization in MDCK cells.
The Chinese journal of physiology.
1999 Mar; 42(1):33-9. doi:
NULL. [PMID: 10405769] - C R Jan, C M Ho, S N Wu, C J Tseng. Multiple effects of econazole on calcium signaling: depletion of thapsigargin-sensitive calcium store, activation of extracellular calcium influx, and inhibition of capacitative calcium entry.
Biochimica et biophysica acta.
1999 Jan; 1448(3):533-42. doi:
10.1016/s0167-4889(98)00159-1. [PMID: 9990306] - C R Jan, C M Ho, S N Wu, C J Tseng. Mechanism of rise and decay of thapsigargin-evoked calcium signals in MDCK cells.
Life sciences.
1999; 64(4):259-67. doi:
10.1016/s0024-3205(98)00561-x. [PMID: 10027760] - B Tunçtan, O Uludag, S Altug, N Abacioglu. Effects of nitric oxide synthase inhibition in lipopolysaccharide-induced sepsis in mice.
Pharmacological research.
1998 Nov; 38(5):405-11. doi:
10.1006/phrs.1998.0381. [PMID: 9806822] - A Gamberucci, R Fulceri, A Benedetti, F L Bygrave. On the mechanism of action of econazole, the capacitative calcium inflow blocker.
Biochemical and biophysical research communications.
1998 Jul; 248(1):75-7. doi:
10.1006/bbrc.1998.8810. [PMID: 9675088] - L Vroye, R Beauwens, J Van Sande, D Daloze, J C Braekman, P E Golstein. The Na+-I- cotransporter of the thyroid: characterisation of new inhibitors.
Pflugers Archiv : European journal of physiology.
1998 Jan; 435(2):259-66. doi:
10.1007/pl00008081. [PMID: 9382940] - I Benkó, A Megyeri, F Hernádi, P Kovács. [Effect of imidazole antifungal agents on colony formation by murine bone marrow CFUc (colony forming units in culture].
Acta pharmaceutica Hungarica.
1996 Nov; 66(6):241-5. doi:
NULL. [PMID: 9604489] - C E Ahnadi, M D Payet, G Dupuis. Effects of staurosporine on the capacitative regulation of the state of the Ca2+ reserves in activated Jurkat T lymphocytes.
Cell calcium.
1996 Jun; 19(6):509-20. doi:
10.1016/s0143-4160(96)90060-3. [PMID: 8842518] - E H Hornstein, D Vassilopoulos, D E Thomas, F K Friedman, G C Tsokos. Modulation of human T-lymphocyte plasma membrane Ca2+ permeability by imidazole antimycotics.
Immunopharmacology and immunotoxicology.
1996 May; 18(2):237-45. doi:
10.3109/08923979609052734. [PMID: 8771369] - T K Ng, R C Chan, F A Adeyemi-Doro, S W Cheung, A F Cheng. Rapid high performance liquid chromatographic assay for antifungal agents in human sera.
The Journal of antimicrobial chemotherapy.
1996 Mar; 37(3):465-72. doi:
10.1093/jac/37.3.465. [PMID: 9182103] - O Scharff, B Foder. Delayed activation of plasma membrane Ca2+ pump in human neutrophils.
Cell calcium.
1994 Dec; 16(6):455-66. doi:
10.1016/0143-4160(94)90075-2. [PMID: 7712539] - P Sargeant, R W Farndale, S O Sage. The imidazole antimycotics econazole and miconazole reduce agonist-evoked protein-tyrosine phosphorylation and evoke membrane depolarisation in human platelets: cautions for their use in studying Ca2+ signalling pathways.
Cell calcium.
1994 Nov; 16(5):413-8. doi:
10.1016/0143-4160(94)90034-5. [PMID: 7532106] - J P Breittmayer, P Berthe, J L Cousin, A Bernard, C Aussel. CD3 monoclonal antibodies evoke the same cytochrome P450-regulated capacitative entry of calcium as thapsigargin in Jurkat T cells.
Cellular immunology.
1993 Nov; 152(1):143-51. doi:
10.1006/cimm.1993.1274. [PMID: 8242757] - J G Vostal, J C Fratantoni. Econazole inhibits thapsigargin-induced platelet calcium influx by mechanisms other than cytochrome P-450 inhibition.
The Biochemical journal.
1993 Oct; 295 ( Pt 2)(?):525-9. doi:
10.1042/bj2950525. [PMID: 8240252] - M P Shakarjian, E Eiseman, R C Penhallow, J B Bolen. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibition in a rat mast cell line. Impairment of tyrosine kinase-dependent signal transduction and the subsequent degranulation response.
The Journal of biological chemistry.
1993 Jul; 268(20):15252-9. doi:
. [PMID: 8325896] - M J Mason, B Mayer, L J Hymel. Inhibition of Ca2+ transport pathways in thymic lymphocytes by econazole, miconazole, and SKF 96365.
The American journal of physiology.
1993 Mar; 264(3 Pt 1):C654-62. doi:
10.1152/ajpcell.1993.264.3.c654. [PMID: 8384787] - S R Alonso-Torre, J Alvarez, M Montero, A Sanchez, J García-Sancho. Control of Ca2+ entry into HL60 and U937 human leukaemia cells by the filling state of the intracellular Ca2+ stores.
The Biochemical journal.
1993 Feb; 289 ( Pt 3)(?):761-6. doi:
10.1042/bj2890761. [PMID: 8382050] - M Montero, J Alvarez, J García-Sancho. Control of plasma-membrane Ca2+ entry by the intracellular Ca2+ stores. Kinetic evidence for a short-lived mediator.
The Biochemical journal.
1992 Dec; 288 ( Pt 2)(?):519-25. doi:
10.1042/bj2880519. [PMID: 1463455] - P Sargeant, W D Clarkson, S O Sage, J W Heemskerk. Calcium influx evoked by Ca2+ store depletion in human platelets is more susceptible to cytochrome P-450 inhibitors than receptor-mediated calcium entry.
Cell calcium.
1992 Oct; 13(9):553-64. doi:
10.1016/0143-4160(92)90035-q. [PMID: 1334809] - W T de Lima, P Sirois, S Jancar. Immune-complex alveolitis in the rat: evidence for platelet activating factor and leukotrienes as mediators of the vascular lesions.
European journal of pharmacology.
1992 Mar; 213(1):63-70. doi:
10.1016/0014-2999(92)90233-t. [PMID: 1323472] - N H Georgopapadakou, B A Dix, S A Smith, J Freudenberger, P T Funke. Effect of antifungal agents on lipid biosynthesis and membrane integrity in Candida albicans.
Antimicrobial agents and chemotherapy.
1987 Jan; 31(1):46-51. doi:
10.1128/aac.31.1.46. [PMID: 3551826] - O Bäck, J Faergemann, R Hörnqvist. Pityrosporum folliculitis: a common disease of the young and middle-aged.
Journal of the American Academy of Dermatology.
1985 Jan; 12(1 Pt 1):56-61. doi:
10.1016/s0190-9622(85)70009-6. [PMID: 3980804] - R Piccolomini, A Arpini, L Cellini, M Pagano. [In vitro anti-fungal activity of the econazole-ornidazole combination (1:10 ratio)].
Bollettino dell'Istituto sieroterapico milanese.
1983 Jul; 62(3):257-61. doi:
NULL. [PMID: 6639779] - M E Kunze, P Todd. An evaluation of Econazole, an antifungal agent, for use in quantitative cell culture experiments.
In vitro.
1983 Mar; 19(3 Pt 1):175-8. doi:
10.1007/bf02618057. [PMID: 6339373] - I Midgley, P J van Bladeren, D R Hawkins, L F Chasseaud, A Darragh, R R Brodie, L M Walmsley. The metabolic fate of 3[H]econazole in man.
Xenobiotica; the fate of foreign compounds in biological systems.
1981 Sep; 11(9):595-608. doi:
10.3109/00498258109045871. [PMID: 7314642] - W Raab, F Högl. [The activity of imidazole derivatives in the presence of human plasma (author's transl)].
Zeitschrift fur Hautkrankheiten.
1981 Jul; 56(13):843-6. doi:
NULL. [PMID: 6267837] - H J Preusser, H Rostek. Freeze-fracture studies of the plasmalemma of Candida albicans after treatment with econazole-nitrate.
Sabouraudia.
1979 Dec; 17(4):389-98. doi:
". [PMID: 397619] - R Wyler, A Murbach, H Möhl. An imidazole derivative (Econazole) as an antifungal agent in cell culture systems.
In vitro.
1979 Oct; 15(10):745-50. doi:
10.1007/bf02618300. [PMID: 521035] - W Rindt, W Geibel, L Appel. [Vaginal absorption of econazole].
Arzneimittel-Forschung.
1979; 29(4):697-9. doi:
NULL. [PMID: 582771] - R R Brodie, L F Chasseaud, L M Walmsley. High-performance liquid chromatographic determination of the antimycotic agent, econazole in plasma.
Journal of chromatography.
1978 Aug; 155(1):209-13. doi:
10.1016/s0021-9673(00)83955-2. [PMID: 681489] - H J Preusser, H Rostek. Econazole effects on Trichophyton rubrum and Candida albicans--electron microscopic and cytochemical studies.
Mykosen. Supplement.
1978; 1(?):314-21. doi:
". [PMID: 400880] - H B Levine. R34000, a dioxolane imidazole in the therapy for experimental coccidioidomycosis. Comparison with miconazole and econazole.
Chest.
1976 Dec; 70(6):755-9. doi:
10.1378/chest.70.6.755. [PMID: 1001052] - D Schlondorff, H Weber. Cyclic nucleotide metabolism in compensatory renal hypertrophy and neonatal kidney growth.
Proceedings of the National Academy of Sciences of the United States of America.
1976 Feb; 73(2):524-8. doi:
10.1073/pnas.73.2.524. [PMID: 1760] - B D Cameron, L F Chasseaud, B Conway, N Fox, T Taylor. Absorption and disposition of econazole nitrate after application to the skins and vaginas of rabbits.
Arzneimittel-Forschung.
1976; 26(11):2054-9. doi:
NULL. [PMID: 1037247]
