Amrinone (BioDeep_00000014996)

   


代谢物信息卡片


Amrinone

化学式: C10H9N3O (187.07455839999997)
中文名称: 氨力农
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CN=CC=C1C2=CNC(=O)C(=C2)N
InChI: InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)

描述信息

C - Cardiovascular system > C01 - Cardiac therapy > C01C - Cardiac stimulants excl. cardiac glycosides > C01CE - Phosphodiesterase inhibitors
D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors > D058987 - Phosphodiesterase 3 Inhibitors
C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent
D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers
D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor
D020011 - Protective Agents > D002316 - Cardiotonic Agents
D000077264 - Calcium-Regulating Hormones and Agents
D049990 - Membrane Transport Modulators

同义名列表

1 个代谢物同义名

Amrinone



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Daniel J Warner, Hongming Chen, Louis-David Cantin, J Gerry Kenna, Simone Stahl, Clare L Walker, Tobias Noeske. Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals. 2012 Dec; 40(12):2332-41. doi: 10.1124/dmd.112.047068. [PMID: 22961681]
  • U Deniz Dincer. Cardiac ryanodine receptor in metabolic syndrome: is JTV519 (K201) future therapy?. Diabetes, metabolic syndrome and obesity : targets and therapy. 2012; 5(?):89-99. doi: 10.2147/dmso.s30005. [PMID: 22563249]
  • Christian de Mey, Nassr Nassr, Gezim Lahu. No relevant cardiac, pharmacokinetic or safety interactions between roflumilast and inhaled formoterol in healthy subjects: an open-label, randomised, actively controlled study. BMC clinical pharmacology. 2011 Jun; 11(?):7. doi: 10.1186/1472-6904-11-7. [PMID: 21631929]
  • Farheen Shah-Khan, Marc H Scheetz, Cybele Ghossein. Biopsy-Proven Acute Tubular Necrosis due to Vancomycin Toxicity. International journal of nephrology. 2011; 2011(?):436856. doi: 10.4061/2011/436856. [PMID: 21716699]
  • Yoshihiro Ko, Kiyozo Morita, Ryuichi Nagahori, Katsushi Kinouchi, Gen Shinohara, Hiroshi Kagawa, Kazuhiro Hashimoto. Myocardial cyclic AMP augmentation with high-dose PDEIII inhibitor in terminal warm blood cardioplegia. Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia. 2009 Oct; 15(5):311-7. doi: ". [PMID: 19901885]
  • Manthena V S Varma, Bo Feng, R Scott Obach, Matthew D Troutman, Jonathan Chupka, Howard R Miller, Ayman El-Kattan. Physicochemical determinants of human renal clearance. Journal of medicinal chemistry. 2009 Aug; 52(15):4844-52. doi: 10.1021/jm900403j. [PMID: 19445515]
  • Yu Liu, Hailiang Chang, Longgang Niu, Wenxin Xue, Xuanping Zhang, Yueqin Liang, Mingsheng Zhang. Effects of propofol on responses of rat isolated renal arteriole to vasoactive agents. Vascular pharmacology. 2009 Aug; 51(2-3):182-9. doi: 10.1016/j.vph.2009.06.003. [PMID: 19540932]
  • Zhibing Qiu, Xin Chen, Ming Xu, Yingshuo Jiang, Liqiong Xiao, Lele Liu, Liming Wang. Evaluation of preoperative intra-aortic balloon pump in coronary patients with severe left ventricular dysfunction undergoing OPCAB surgery: early and mid-term outcomes. Journal of cardiothoracic surgery. 2009 Jul; 4(?):39. doi: 10.1186/1749-8090-4-39. [PMID: 19635155]
  • Won-Il Choi, Kun Young Kwon, Jeong Wook Seo, John Beagle, Deborah A Quinn, Charles A Hales. The role of phosphodiesterase 3 in endotoxin-induced acute kidney injury. BMC infectious diseases. 2009 Jun; 9(?):80. doi: 10.1186/1471-2334-9-80. [PMID: 19486524]
  • Can Kucuk, Alper Akcan, Hizi Akyýldýz, Hulya Akgun, Sebahattin Muhtaroglu, Erdogan Sozuer. Effects of amrinone in an experimental model of hepatic ischemia-reperfusion injury. The Journal of surgical research. 2009 Jan; 151(1):74-9. doi: 10.1016/j.jss.2008.02.008. [PMID: 18468627]
  • Christine Dieterich, Angela Puey, Sylvia Lin, Sylvia Lyn, Robert Swezey, Anna Furimsky, David Fairchild, Jon C Mirsalis, Hanna H Ng. Gene expression analysis reveals new possible mechanisms of vancomycin-induced nephrotoxicity and identifies gene markers candidates. Toxicological sciences : an official journal of the Society of Toxicology. 2009 Jan; 107(1):258-69. doi: 10.1093/toxsci/kfn203. [PMID: 18930951]
  • Robert M Coward, Culley C Carson. Tadalafil in the treatment of erectile dysfunction. Therapeutics and clinical risk management. 2008 Dec; 4(6):1315-30. doi: 10.2147/tcrm.s3336. [PMID: 19337438]
  • R Scott Obach, Franco Lombardo, Nigel J Waters. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals. 2008 Jul; 36(7):1385-405. doi: 10.1124/dmd.108.020479. [PMID: 18426954]
  • Su-Gang Gong, Jing-Ming Liu. [Protection of amrinone against lung injury induced by ischemia/reperfusion in rats]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. 2007 Jun; 9(3):233-6. doi: NULL. [PMID: 17582263]
  • Trung C Nguyen, Joseph A Carcillo. Bench-to-bedside review: thrombocytopenia-associated multiple organ failure--a newly appreciated syndrome in the critically ill. Critical care (London, England). 2006; 10(6):235. doi: 10.1186/cc5064. [PMID: 17096864]
  • Alper Akcan, Can Kucuk, Engin Ok, Ozlem Canoz, Sebahattin Muhtaroglu, Namik Yilmaz, Zeki Yilmaz. The effect of amrinone on liver regeneration in experimental hepatic resection model. The Journal of surgical research. 2006 Jan; 130(1):66-72. doi: 10.1016/j.jss.2005.07.020. [PMID: 16154150]
  • Ilhami Celik, Mustafa Cihangiroglu, Nevin Ilhan, Nusret Akpolat, H Handan Akbulut. Protective effects of different antioxidants and amrinone on vancomycin-induced nephrotoxicity. Basic & clinical pharmacology & toxicology. 2005 Nov; 97(5):325-32. doi: 10.1111/j.1742-7843.2005.pto_153.x. [PMID: 16236146]
  • Masanori Onomoto, Isao Tsuneyoshi, Arata Yonetani, Shoich Suehiro, Kazuhisa Matsumoto, Ryuzo Sakata, Yuichi Kanmura. Differential pharmacologic sensitivities of phosphodiesterase-3 inhibitors among human isolated gastroepiploic, internal mammary, and radial arteries. Anesthesia and analgesia. 2005 Oct; 101(4):950-956. doi: 10.1213/01.ane.0000172114.30383.23. [PMID: 16192501]
  • Dion R Brocks, Tara J Spencer, Anooshirvan Shayeganpour. A sensitive and specific high performance liquid chromatographic assay for milrinone in rat and human plasma using a commercially available internal standard and low sample volume. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. 2005 Jun; 8(2):124-31. doi: NULL. [PMID: 16124923]
  • Denji Tobata, Koji Takao, Manabu Mochizuki, Ryohei Nishimura, Nobuo Sasaki. Effects of dopamine, dobutamine, amrinone and milrinone on regional blood flow in isoflurane anesthetized dogs. The Journal of veterinary medical science. 2004 Sep; 66(9):1097-105. doi: 10.1292/jvms.66.1097. [PMID: 15472474]
  • Feng Yin, Ping Li, Ming Zheng, Li Chen, Qi Xu, Kai Chen, Yong-yu Wang, You-yi Zhang, Chide Han. Interleukin-6 family of cytokines mediates isoproterenol-induced delayed STAT3 activation in mouse heart. The Journal of biological chemistry. 2003 Jun; 278(23):21070-5. doi: 10.1074/jbc.m211028200. [PMID: 12665506]
  • Hakan Kilicarslan, Sahin Yildirim, Ihsan Bagcivan, Gokhan Gokce, Bulent Sarac, Yusuf Sarioglu. The effect of chronic renal failure on phosphodiesterase inhibitor-induced relaxation responses in rabbit cavernosal strips. European journal of pharmacology. 2003 Feb; 462(1-3):155-60. doi: 10.1016/s0014-2999(03)01296-2. [PMID: 12591108]
  • Athar Sadiq, Noriko Tamura, Minako Yoshida, Yasunari Hoshiba, Asako Kumagai, Teruhisa Tanabe, Shunnosuke Handa, Yasuo Ikeda, Shinya Goto. Possible contribution of acetylamrinone and its enhancing effects on platelet aggregation under shear stress conditions in the onset of thrombocytopenia in patients treated with amrinone. Thrombosis research. 2003; 111(6):357-61. doi: 10.1016/j.thromres.2003.09.024. [PMID: 14698653]
  • Takashi Kobayashi, Yasuhiko Sugawara, Takao Ohkubo, Hiroshi Imamura, Masatoshi Makuuchi. Effects of amrinone on hepatic ischemia-reperfusion injury in rats. Journal of hepatology. 2002 Jul; 37(1):31-8. doi: 10.1016/s0168-8278(02)00084-3. [PMID: 12076859]
  • R Karabulut, K Sönmez, B Sancak, Z Türkyilmaz, B Demiroğullari, I O Ozen, G Ekingen, S Candan, A C Başaklar, N Kale. Effects of amrinone on bilateral renal ischemia/reperfusion injury. Urological research. 2002 Jul; 30(3):164-8. doi: 10.1007/s00240-002-0256-3. [PMID: 12111179]
  • Mutsuhito Kikura, Shigehito Sato. The efficacy of preemptive Milrinone or Amrinone therapy in patients undergoing coronary artery bypass grafting. Anesthesia and analgesia. 2002 Jan; 94(1):22-30, table of contents. doi: 10.1097/00000539-200201000-00005. [PMID: 11772795]
  • P Laitinen, J Ahonen, K T Olkkola, K Peltola, P Rautiainen, J Räsänen. Pharmacokinetics of amrinone in neonates and infants. Journal of cardiothoracic and vascular anesthesia. 2000 Aug; 14(4):378-82. doi: 10.1053/jcan.2000.7922. [PMID: 10972600]
  • T Sakane, Y Ishibashi, T Shimada, N Takahashi, T Sugamori, Y Hirano, S Ohata, S I Inoue, K Nakamura, Y Murakami. Impaired vasodilatation response to amrinone in the forearm of patients with congestive heart failure: role of endothelium-derived nitric oxide. Journal of cardiovascular pharmacology. 2000 Aug; 36(2):188-95. doi: 10.1097/00005344-200008000-00008. [PMID: 10942160]
  • M Kanda, S Yasuda, Y Goto, H Sumida, T Baba, T Noguchi, H Nonogi. Diuretic effect of phosphodiesterase inhibitors depends on baseline renal function in patients with congestive heart failure. The American journal of cardiology. 1999 Apr; 83(8):1274-7, A9. doi: 10.1016/s0002-9149(99)00073-9. [PMID: 10215299]
  • K Takeuchi, P J del Nido, A E Ibrahim, H Cao-Danh, I Friehs, P Glynn, D Poutias, D B Cowan, F X McGowan. Vesnarinone and amrinone reduce the systemic inflammatory response syndrome. The Journal of thoracic and cardiovascular surgery. 1999 Feb; 117(2):375-82. doi: 10.1016/s0022-5223(99)70436-8. [PMID: 9918980]
  • T Kerttula, J Alanko, E Seppälä, A Riutta, I Mucha, E Sievi, S Kaukinen. Amrinone, a phosphodiesterase III inhibitor, and arachidonic acid metabolism in humans. Journal of cardiovascular pharmacology. 1999 Jan; 33(1):140-3. doi: 10.1097/00005344-199901000-00021. [PMID: 9890409]
  • T Sakane, Y Ishibashi, T Shimada, S Inoue, T Sugamori, Y Hirano, N Takahashi, S Ohata, T Asanuma, H Kato, H Yoshitomi, K Sano, Y Murakami, R Murakami. [Endothelial-derived nitric oxide mediates the peripheral vasodilatory effects of amrinone in humans]. Journal of cardiology. 1999 Jan; 33(1):13-9. doi: NULL. [PMID: 10028457]
  • H Okabe, Y Kaneko, N Nagata, J Kobayashi, S Kanemoto, H Ka, J Fuijmoto, T Fuijwara. [Hemodynamic effects of amrinone or milrinone in infant after right heart bypass operation]. Kyobu geka. The Japanese journal of thoracic surgery. 1998 Jul; 51(7):543-8. doi: NULL. [PMID: 9666655]
  • R De Vecchis, G Pucciarelli, L Nocerino, M Cocozza, A Setaro, G Torre, F Imperatore. [The dobutamine-dopamine combination versus amrinone in congestive heart failure with a marked edematogenic sign complicated by functional kidney failure. A comparison between 2 different models of inotropic stimulation and diuresis potentiation]. Minerva cardioangiologica. 1998 May; 46(5):163-74. doi: NULL. [PMID: 9842199]
  • J P Rathmell, R C Prielipp, J F Butterworth, E Williams, F Villamaria, L Testa, C Viscomi, F P Ittleman, C E Baisden, R L Royster. A multicenter, randomized, blind comparison of amrinone with milrinone after elective cardiac surgery. Anesthesia and analgesia. 1998 Apr; 86(4):683-90. doi: 10.1097/00000539-199804000-00001. [PMID: 9539583]
  • G Haskó, C Szabó, Z H Németh, A L Salzman, E S Vizi. Suppression of IL-12 production by phosphodiesterase inhibition in murine endotoxemia is IL-10 independent. European journal of immunology. 1998 Feb; 28(2):468-72. doi: 10.1002/(sici)1521-4141(199802)28:02<468::aid-immu468>3.0.co;2-z. [PMID: 9521054]
  • J Ishiki. [Perioperative management of renal circulation]. Masui. The Japanese journal of anesthesiology. 1997 Nov; 46 Suppl(?):S68-73. doi: NULL. [PMID: 9508587]
  • Z H Németh, G Haskó, C Szabó, E S Vizi. Amrinone and theophylline differentially regulate cytokine and nitric oxide production in endotoxemic mice. Shock (Augusta, Ga.). 1997 May; 7(5):371-5. doi: 10.1097/00024382-199705000-00010. [PMID: 9165673]
  • S Takeda, T Takano, K Nakanishi, J Nejima, M Takayama, C Kim, R Ogawa. Amrinone improves lung compliance in patients receiving mechanical ventilation for cardiogenic pulmonary edema. Acta anaesthesiologica Scandinavica. 1997 May; 41(5):624-8. doi: 10.1111/j.1399-6576.1997.tb04754.x. [PMID: 9181165]
  • Y Okuno, T Mashimo, M Takashina, S Hagihira, Y Inagaki, T Mori, I Yoshiya. [Hemodynamic effects of amrinone combined with dopamine in patients undergoing living renal transplantation]. Masui. The Japanese journal of anesthesiology. 1997 Jan; 46(1):87-94. doi: NULL. [PMID: 9028089]
  • E M Allen, M Rowin, J B Pappas, D D Vernon, J M Dean. Hemodynamic effects of N-acetylamrinone in a porcine model of group B streptococcal sepsis. Drug metabolism and disposition: the biological fate of chemicals. 1996 Sep; 24(9):1028-31. doi: NULL. [PMID: 8886615]
  • J B Pappas, E M Allen, M Ross, W Banner. HPLC micromethod for amrinone and metabolites in patients receiving concurrent cephalosporin therapy. Clinical chemistry. 1996 May; 42(5):761-5. doi: 10.1093/clinchem/42.5.761. [PMID: 8653904]
  • T C Vary. Amrinone prevents the inhibition of muscle pyruvate dehydrogenase complex activity during sepsis. Shock (Augusta, Ga.). 1996 Mar; 5(3):229-32. doi: 10.1097/00024382-199603000-00011. [PMID: 8696989]
  • G K Sorensen, C Ramamoorthy, A M Lynn, J French, J G Stevenson. Hemodynamic effects of amrinone in children after Fontan surgery. Anesthesia and analgesia. 1996 Feb; 82(2):241-6. doi: 10.1097/00000539-199602000-00004. [PMID: 8561320]
  • Y Fujita. Amrinone reverses bupivacaine-induced regional myocardial dysfunction. Acta anaesthesiologica Scandinavica. 1996 Jan; 40(1):47-52. doi: 10.1111/j.1399-6576.1996.tb04387.x. [PMID: 8904259]
  • G Joseph, Y Zhao, W Klaus. [Pharmacologic action profile of crataegus extract in comparison to epinephrine, amirinone, milrinone and digoxin in the isolated perfused guinea pig heart]. Arzneimittel-Forschung. 1995 Dec; 45(12):1261-5. doi: ". [PMID: 8595081]
  • T Hirozane, A Matsumori, Y Furukawa, S Matsui, Y Sato, Y Matoba, S Sasayama. Beneficial effect of amrinone on murine cardiac allograft survival. Clinical and experimental immunology. 1995 Oct; 102(1):186-91. doi: 10.1111/j.1365-2249.1995.tb06654.x. [PMID: 7554388]
  • M Günnicker, M Brinkmann, T J Donovan, U Freund, M Schieffer, J C Reidemeister. The efficacy of amrinone or adrenaline on low cardiac output following cardiopulmonary bypass in patients with coronary artery disease undergoing preoperative beta-blockade. The Thoracic and cardiovascular surgeon. 1995 Jun; 43(3):153-60. doi: 10.1055/s-2007-1013790. [PMID: 7570567]
  • G D Williams, G K Sorensen, R Oakes, D P Boggs, J J Mulroy, A M Lynn. Amrinone loading during cardiopulmonary bypass in neonates, infants, and children. Journal of cardiothoracic and vascular anesthesia. 1995 Jun; 9(3):278-82. doi: 10.1016/s1053-0770(05)80321-0. [PMID: 7669960]
  • V Cody, A Wojtczak, F B Davis, P J Davis, S D Blas. Structure-activity relationships of milrinone analogues determined in vitro in a rabbit heart membrane Ca(2+)-ATPase model. Journal of medicinal chemistry. 1995 May; 38(11):1990-7. doi: 10.1021/jm00011a018. [PMID: 7783130]
  • A Hellinger, K Wolter, G Marggraf, R Pentz, E Fritschka. Elimination of amrinone during continuous veno-venous haemofiltration after cardiac surgery. European journal of clinical pharmacology. 1995; 48(1):57-9. doi: 10.1007/bf00202173. [PMID: 7621849]
  • Y Ruttimann, R Chioléro, J P Revelly, N Jeanprêtre, Y Schutz. Thermogenic effect of amrinone in healthy men. Critical care medicine. 1994 Aug; 22(8):1235-40. doi: 10.1097/00003246-199408000-00006. [PMID: 8045142]
  • E M Allen-Webb, M P Ross, J B Pappas, E C McGough, W Banner. Age-related amrinone pharmacokinetics in a pediatric population. Critical care medicine. 1994 Jun; 22(6):1016-24. doi: 10.1097/00003246-199406000-00022. [PMID: 8205809]
  • H Migulla, S Bauer, H Kewitz, I Roots. [Micromethod for determination of amrinone and acetylamrinone in plasma and urine with HPLC]. Die Pharmazie. 1994 Apr; 49(4):290-1. doi: NULL. [PMID: 8197232]
  • S Laganière, L Goernert. Amrinone and N-acetylamrinone assay in human plasma using solid-phase extraction and reversed-phase chromatography. Journal of pharmaceutical and biomedical analysis. 1994 Mar; 12(3):407-11. doi: 10.1016/0731-7085(94)90018-3. [PMID: 8031942]
  • J I Berger, R L Gibson, W R Clarke, T A Standaert, G J Redding, W R Henderson, W E Truog. Effect of amrinone during group B Streptococcus-induced pulmonary hypertension in piglets. Pediatric pulmonology. 1993 Nov; 16(5):303-10. doi: 10.1002/ppul.1950160506. [PMID: 8255635]
  • W C Lenox, C A Hirshman. Amrinone attenuates airway constriction during halothane anesthesia. Anesthesiology. 1993 Oct; 79(4):789-94. doi: 10.1097/00000542-199310000-00022. [PMID: 8214759]
  • A M Lynn, G K Sorensen, G D Williams, G D Anderson, K E Opheim. Hemodynamic effects of amrinone and colloid administration in children following cardiac surgery. Journal of cardiothoracic and vascular anesthesia. 1993 Oct; 7(5):560-5. doi: 10.1016/1053-0770(93)90315-c. [PMID: 8268437]
  • P Arner, J Hellmér, E Hagström-Toft, J Bolinder. Effect of phosphodiesterase inhibition with amrinone or theophylline on lipolysis and blood flow in human adipose tissue in vivo as measured with microdialysis. Journal of lipid research. 1993 Oct; 34(10):1737-43. doi: 10.1016/s0022-2275(20)35736-9. [PMID: 8245724]
  • S Lawless, I Restaino, S Azin, D Corddry. Effect of continuous arteriovenous haemofiltration on pharmacokinetics of amrinone. Clinical pharmacokinetics. 1993 Jul; 25(1):80-2. doi: 10.2165/00003088-199325010-00006. [PMID: 8354019]
  • M P Ross, E M Allen-Webb, J B Pappas, E C McGough. Amrinone-associated thrombocytopenia: pharmacokinetic analysis. Clinical pharmacology and therapeutics. 1993 Jun; 53(6):661-7. doi: 10.1038/clpt.1993.87. [PMID: 8513658]
  • L Lindgren, T Randell, N Suzuki, J Kyttä, A Yli-Hankala, P H Rosenberg. The effect of amrinone on recovery from severe bupivacaine intoxication in pigs. Anesthesiology. 1992 Aug; 77(2):309-15. doi: 10.1097/00000542-199208000-00014. [PMID: 1642351]
  • E Stengele, D Trenk. [Use of amrinone in terminal dialysis-dependent renal failure]. Medizinische Klinik (Munich, Germany : 1983). 1992 May; 87(5):278-80. doi: NULL. [PMID: 1614376]
  • P Costa, C Agrò, G Gulotta, G Papa, F Piazza, F Ronga, B Sparacia, A Sansone. [Efficacy and safety of amrinone in the treatment of heart insufficiency in intensive care]. Minerva anestesiologica. 1992 May; 58(5):301-10. doi: NULL. [PMID: 1635643]
  • J H Levy, J M Bailey. Perioperative experience with amrinone. European journal of anaesthesiology. Supplement. 1992; 5(?):15-9. doi: NULL. [PMID: 1600963]
  • J M Bailey, J H Levy, H G Rogers, F Szlam, C C Hug. Pharmacokinetics of amrinone during cardiac surgery. Anesthesiology. 1991 Dec; 75(6):961-8. doi: 10.1097/00000542-199112000-00006. [PMID: 1741517]
  • S Lawless, G Burckart, G Piccola, W Diven, M Miles, A Zaritsky. Simplified assay of amrinone in plasma by high-performance liquid chromatography. Therapeutic drug monitoring. 1990 Nov; 12(6):570-3. doi: 10.1097/00007691-199011000-00010. [PMID: 2275004]
  • H Masuoka, M Ito, T Nakano, M Naka, T Tanaka. Effects of amrinone and enoximone on the subclasses of cyclic AMP phosphodiesterase from human heart and kidney. Journal of cardiovascular pharmacology. 1990 Feb; 15(2):302-7. doi: 10.1097/00005344-199002000-00018. [PMID: 1689427]
  • M Berner, C Jaccard, I Oberhansli, J C Rouge, B Friedli. Hemodynamic effects of amrinone in children after cardiac surgery. Intensive care medicine. 1990; 16(2):85-8. doi: 10.1007/bf02575299. [PMID: 2332544]
  • S Lawless, G Burckart, W Diven, A Thompson, R Siewers. Amrinone in neonates and infants after cardiac surgery. Critical care medicine. 1989 Aug; 17(8):751-4. doi: 10.1097/00003246-198908000-00006. [PMID: 2752768]
  • A S Maisel, C M Wright, S M Carter, M Ziegler, H J Motulsky. Tachyphylaxis with amrinone therapy: association with sequestration and down-regulation of lymphocyte beta-adrenergic receptors. Annals of internal medicine. 1989 Feb; 110(3):195-201. doi: 10.7326/0003-4819-110-3-195. [PMID: 2536258]
  • C T Eason, J I Usansky, G P Henry, P Powles, F W Bonner. The relationship between the pharmacokinetics of amrinone in the marmoset and platelet effects. European journal of drug metabolism and pharmacokinetics. 1988 Apr; 13(2):129-33. doi: 10.1007/bf03191314. [PMID: 3145204]
  • V H Makela, P A Kapur. Is milrinone equivalent to amrinone during enflurane anesthesia in the dog?. Anesthesia and analgesia. 1988 Apr; 67(4):349-55. doi: NULL. [PMID: 3354869]
  • C T Eason, A Pattison, D D Howells, F W Bonner, J F Martin. The effects of amrinone, cyclophosphamide and anti-platelet serum on platelet production in the Gunn rat. Journal of applied toxicology : JAT. 1988 Feb; 8(1):29-34. doi: 10.1002/jat.2550080106. [PMID: 3356862]
  • H G Eigendorf, S Nagel. [Analysis of amrinone. 3. Determination of amrinone in serum]. Die Pharmazie. 1987 Dec; 42(12):861. doi: NULL. [PMID: 3444854]
  • P J Davis, V Cody, F B Davis, P R Warnick, M Schoenl, L Edwards. Competition of milrinone, a non-iodinated cardiac inotropic agent, with thyroid hormone for binding sites on human serum prealbumin (TBPA). Biochemical pharmacology. 1987 Nov; 36(21):3635-40. doi: 10.1016/0006-2952(87)90013-x. [PMID: 3675620]
  • B F Uretsky, C E Lawless, J G Verbalis, A M Valdes, J A Kolesar, P S Reddy. Combined therapy with dobutamine and amrinone in severe heart failure. Improved hemodynamics and increased activation of the renin-angiotensin system with combined intravenous therapy. Chest. 1987 Oct; 92(4):657-62. doi: 10.1378/chest.92.4.657. [PMID: 3308346]
  • V H Makela, P A Kapur. Amrinone and verapamil-propranolol induced cardiac depression during isoflurane anesthesia in dogs. Anesthesiology. 1987 Jun; 66(6):792-7. doi: 10.1097/00000542-198706000-00013. [PMID: 3592277]
  • H Wilson, M L Rocci, K T Weber, V Andrews, M J Likoff. Pharmacokinetics and hemodynamics of amrinone in patients with chronic cardiac failure of diverse etiology. Research communications in chemical pathology and pharmacology. 1987 Apr; 56(1):3-19. doi: NULL. [PMID: 3589153]
  • V H Makela, P A Kapur. Amrinone blunts cardiac depression caused by enflurane or isoflurane anesthesia in the dog. Anesthesia and analgesia. 1987 Mar; 66(3):215-21. doi: NULL. [PMID: 3826663]
  • P Dorigo, R M Gaion, A Giacometti, G Ceroni, A Marcomini, I Maragno. Amrinone action on guinea-pig isolated stomach fundus. Archives internationales de pharmacodynamie et de therapie. 1987 Jan; 285(1):137-47. doi: . [PMID: 3579421]
  • R A Hamilton, S F Kowalsky, E M Wright, P Cernak, D P Benziger, R M Stroshane, J Edelson. Effect of the acetylator phenotype on amrinone pharmacokinetics. Clinical pharmacology and therapeutics. 1986 Dec; 40(6):615-9. doi: 10.1038/clpt.1986.235. [PMID: 3780123]
  • J M Hartog, P R Saxena, P D Verdouw. Inotropic and vasodilating properties of amrinone depend on the mode of administration. European heart journal. 1986 Dec; 7(12):1067-76. doi: 10.1093/oxfordjournals.eurheartj.a062017. [PMID: 3830202]
  • V H Makela, P A Kapur. Dose-related cardiovascular effects of amrinone during enflurane anesthesia in the dog. Anesthesia and analgesia. 1986 Aug; 65(8):849-52. doi: NULL. [PMID: 3729021]
  • P Dorigo, I Maragno. Interaction of amrinone with endogenous adenosine in guinea-pig atria. British journal of pharmacology. 1986 Apr; 87(4):623-9. doi: 10.1111/j.1476-5381.1986.tb14578.x. [PMID: 3708202]
  • V Koprda, T Trnovec, H Landmann. The binding of amrinone to plasma proteins. Die Pharmazie. 1986 Apr; 41(4):300-1. doi: NULL. [PMID: 3725885]
  • J Edelson, R Stroshane, D P Benziger, R Cody, J Benotti, W B Hood, K Chatterjee, C Luczkowec, C Krebs, R Schwartz. Pharmacokinetics of the bipyridines amrinone and milrinone. Circulation. 1986 Mar; 73(3 Pt 2):III145-52. doi: NULL. [PMID: 3510771]
  • I Kosugi, K Tajimi, T Gonda, O Fukatsu, S Ueda. [Effect of amrinone on hemodynamics, oxygen consumption and plasma catecholamine levels in endotoxin injected dogs]. Masui. The Japanese journal of anesthesiology. 1985 Sep; 34(9):1223-8. doi: NULL. [PMID: 4087357]
  • M M Boucek, R Chang, D P Synhorst. Hemodynamic consequences of inotropic support with digoxin or amrinone in lambs with ventricular septal defect. Pediatric research. 1985 Sep; 19(9):887-91. doi: 10.1203/00006450-198509000-00002. [PMID: 4047755]
  • M Goenen, O Pedemonte, P Baele, J Col. Amrinone in the management of low cardiac output after open heart surgery. The American journal of cardiology. 1985 Jul; 56(3):33B-38B. doi: 10.1016/0002-9149(85)91194-4. [PMID: 4025158]
  • H L Lippton, P M Horwitz, D B McNamara, L J Ignarro, A Z Landry, A L Hyman, P J Kadowitz. The effects of amrinone on human platelet aggregation: evidence that amrinone does not act through a cyclic nucleotide mechanism in platelet rich plasma. Prostaglandins, leukotrienes, and medicine. 1985 May; 18(2):193-204. doi: 10.1016/0262-1746(85)90019-8. [PMID: 3925461]
  • I Kosugi, T Gonda, K Okada, K Tajimi, N Moriyasu, O Fukatsu. [Effects of amrinone on hemodynamics, oxygen consumption and plasma catecholamine levels in anesthetized dogs]. Masui. The Japanese journal of anesthesiology. 1985 Apr; 34(4):429-33. doi: NULL. [PMID: 4021088]
  • M Packer, N Medina, M Yushak. Hemodynamic and clinical limitations of long-term inotropic therapy with amrinone in patients with severe chronic heart failure. Circulation. 1984 Dec; 70(6):1038-47. doi: 10.1161/01.cir.70.6.1038. [PMID: 6388899]
  • D el Allaf, V D'Orio, J Carlier. The new inotropic phosphodiesterase inhibitors. Archives internationales de physiologie et de biochimie. 1984 Nov; 92(4):S69-79. doi: 10.3109/13813458409071165. [PMID: 6085243]
  • R DiBianco, R Shabetai, B D Silverman, C V Leier, J R Benotti. Oral amrinone for the treatment of chronic congestive heart failure: results of a multicenter randomized double-blind and placebo-controlled withdrawal study. Journal of the American College of Cardiology. 1984 Nov; 4(5):855-66. doi: 10.1016/s0735-1097(84)80044-3. [PMID: 6386932]
  • P T Wilmshurst, D S Thompson, S M Juul, B S Jenkins, D J Coltart, M M Webb-Peploe. Comparison of the effects of amrinone and sodium nitroprusside on haemodynamics, contractility, and myocardial metabolism in patients with cardiac failure due to coronary artery disease and dilated cardiomyopathy. British heart journal. 1984 Jul; 52(1):38-48. doi: 10.1136/hrt.52.1.38. [PMID: 6743422]
  • M Packer, N Medina, M Yushak. Correction of dilutional hyponatremia in severe chronic heart failure by converting-enzyme inhibition. Annals of internal medicine. 1984 Jun; 100(6):782-9. doi: 10.7326/0003-4819-100-6-782. [PMID: 6326629]