tenoxicam (BioDeep_00000014994)
Secondary id: BioDeep_00000018686
代谢物信息卡片
化学式: C13H11N3O4S2 (337.0190966)
中文名称: 替诺昔康
谱图信息:
最多检出来源 Viridiplantae(plant) 50%
分子结构信息
SMILES: CN1C(=C(C2=C(S1(=O)=O)C=CS2)O)C(=O)NC3=CC=CC=N3
InChI: InChI=1S/C13H11N3O4S2/c1-16-10(13(18)15-9-4-2-3-6-14-9)11(17)12-8(5-7-21-12)22(16,19)20/h2-7,17H,1H3,(H,14,15,18)
描述信息
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AC - Oxicams
D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000893 - Anti-Inflammatory Agents
D004791 - Enzyme Inhibitors
同义名列表
1 个代谢物同义名
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:32192
- KEGG: C75797
- KEGGdrug: D01767
- PubChem: 54677971
- PubChem: 5282194
- Metlin: METLIN2686
- DrugBank: DB00469
- ChEMBL: CHEMBL3188633
- ChEMBL: CHEMBL302795
- CAS: 59804-37-4
- MoNA: CO000445
- MoNA: CO000444
- MoNA: CO000443
- MoNA: CO000442
- MoNA: CO000441
- PMhub: MS000004552
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Rahul Maheshwari, Mayank Sharma, Vijay R Chidrawar. Niosomes based formulation containing tenoxicam: A newer solution for the rheumatic diseases.
Annales pharmaceutiques francaises.
2023 Nov; ?(?):. doi:
10.1016/j.pharma.2023.10.010
. [PMID: 37923009] - Nobuaki Ishihama, Seung-Won Choi, Yoshiteru Noutoshi, Ivana Saska, Shuta Asai, Kaori Takizawa, Sheng Yang He, Hiroyuki Osada, Ken Shirasu. Oxicam-type non-steroidal anti-inflammatory drugs inhibit NPR1-mediated salicylic acid pathway.
Nature communications.
2021 12; 12(1):7303. doi:
10.1038/s41467-021-27489-w
. [PMID: 34911942] - Nehal Salahuddin, Mohamed Gaber, Sahar Elneanaey, Michael R Snowdon, Mohamed A Abdelwahab. Co-delivery of norfloxacin and tenoxicam in Ag-TiO2/poly(lactic acid) nanohybrid.
International journal of biological macromolecules.
2021 Jun; 180(?):771-781. doi:
10.1016/j.ijbiomac.2021.03.033
. [PMID: 33705836] - Saud Bawazeer, Dalia Farag A El-Telbany, Majid Mohammad Al-Sawahli, Gamal Zayed, Ahmed Abdallah A Keed, Abdelaziz E Abdelaziz, Doaa H Abdel-Naby. Effect of nanostructured lipid carriers on transdermal delivery of tenoxicam in irradiated rats.
Drug delivery.
2020 Dec; 27(1):1218-1230. doi:
10.1080/10717544.2020.1803448
. [PMID: 32772730] - Gergő Dargó, Dávid Bajusz, Kristóf Simon, Judit Müller, György T Balogh. Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design.
Journal of medicinal chemistry.
2020 02; 63(4):1763-1774. doi:
10.1021/acs.jmedchem.0c00046
. [PMID: 31995375] - Mohammed H Elkomy, Shahira F El Menshawe, Hussein M Eid, Ahmed M A Ali. Development of a nanogel formulation for transdermal delivery of tenoxicam: a pharmacokinetic-pharmacodynamic modeling approach for quantitative prediction of skin absorption.
Drug development and industrial pharmacy.
2017 Apr; 43(4):531-544. doi:
10.1080/03639045.2016.1268153
. [PMID: 27910712] - M Asadykkag Madni, Ahman Raza, Sikandar Abbas, Nayab Tahir, Mubashar Rehman, Prince Muhammad Kashif, Muhammad Imran Khan. DETERMINATION OF TENOXICAM IN THE PLASMA BY REVERSE PHASE HPLC METHOD USING SINGLE STEP EXTRACTION TECHNIQUE: A RELIABLE AND COST EFFECTIVE APPROACH.
Acta poloniae pharmaceutica.
2016 Sep; 73(5):1123-1128. doi:
NULL
. [PMID: 29638052] - Anupa Majumdar, Munna Sarkar. Small Mismatches in Fatty Acyl Tail Lengths Can Effect Non Steroidal Anti-Inflammatory Drug Induced Membrane Fusion.
The journal of physical chemistry. B.
2016 06; 120(21):4791-802. doi:
10.1021/acs.jpcb.6b03583
. [PMID: 27153337] - Shanna L Karls, Kelli R Snyder, Peter J Neibert. Effectiveness of Corticosteroid Injections in the Treatment of Plantar Fasciitis.
Journal of sport rehabilitation.
2016 May; 25(2):202-7. doi:
10-1123/jsr.2014-0234
. [PMID: 26062179] - Saritha Alladi, Nalini R Shastri. Semi solid matrix formulations of meloxicam and tenoxicam: an in vitro and in vivo evaluation.
Archives of pharmacal research.
2015; 38(5):801-12. doi:
10.1007/s12272-014-0396-3
. [PMID: 24752862] - Gabriella Tamasi, Caterina Bernini, Gianfranco Corbini, Natalie F Owens, Luigi Messori, Federica Scaletti, Lara Massai, Pietro Lo Giudice, Renzo Cini. Synthesis, spectroscopic and DFT structural characterization of two novel ruthenium(III) oxicam complexes. In vivo evaluation of anti-inflammatory and gastric damaging activities.
Journal of inorganic biochemistry.
2014 May; 134(?):25-35. doi:
10.1016/j.jinorgbio.2014.01.011
. [PMID: 24518539] - Junichi Shirako, Marina Kawasaki, Kotoe Komine, Yoko Kunisue, Masaru Terada, Chizuko Sasaki, Wataru Irie, Chikako Murakami, Keiko Tonooka, Koji Tomobe, Tatsuo Shinozuka. Simultaneous determination for oxicam non-steroidal anti-inflammatory drugs in human serum by liquid chromatography-tandem mass spectrometry.
Forensic science international.
2013 Apr; 227(1-3):100-2. doi:
10.1016/j.forsciint.2012.11.016
. [PMID: 23273940] - Sutapa Mondal Roy, Munna Sarkar. Effect of lipid molecule headgroup mismatch on non steroidal anti-inflammatory drugs induced membrane fusion.
Langmuir : the ACS journal of surfaces and colloids.
2011 Dec; 27(24):15054-64. doi:
10.1021/la2030186
. [PMID: 21999838] - Katarzyna Czapla, Beata Korchowiec, Monika Orlof, Jenifer Rubio Magnieto, Ewa Rogalska. Enzymatic probing of model lipid membranes: phospholipase A2 activity toward monolayers modified by oxicam NSAIDs.
The journal of physical chemistry. B.
2011 Jul; 115(29):9290-8. doi:
10.1021/jp202716k
. [PMID: 21682312] - David Buttar, Nicola Colclough, Stefan Gerhardt, Philip A MacFaul, Scott D Phillips, Alleyn Plowright, Paul Whittamore, Kin Tam, Klaus Maskos, Stefan Steinbacher, Holger Steuber. A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
Bioorganic & medicinal chemistry.
2010 Nov; 18(21):7486-96. doi:
10.1016/j.bmc.2010.08.052
. [PMID: 20869876] - D Ulusoy Karatopuk, Alpaslan Gökçımen. Effect of tenoxicam on rat liver tissue.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology.
2010 Jun; 21(2):146-52. doi:
10.4318/tjg.2010.0073
. [PMID: 20872328] - Marcelo Soares Privado, Adriana Machado Issy, Vera Lucia Lanchote, João Batista Santos Garcia, Rioko Kimiko Sakata. Epidural versus intravenous fentanyl for postoperative analgesia following orthopedic surgery: randomized controlled trial.
Sao Paulo medical journal = Revista paulista de medicina.
2010 Jan; 128(1):5-9. doi:
10.1590/s1516-31802010000100002
. [PMID: 20512273] - Sutapa Mondal, Munna Sarkar. Non-steroidal anti-inflammatory drug induced membrane fusion: concentration and temperature effects.
The journal of physical chemistry. B.
2009 Dec; 113(51):16323-31. doi:
10.1021/jp9069527
. [PMID: 19954169] - Manthena V S Varma, Bo Feng, R Scott Obach, Matthew D Troutman, Jonathan Chupka, Howard R Miller, Ayman El-Kattan. Physicochemical determinants of human renal clearance.
Journal of medicinal chemistry.
2009 Aug; 52(15):4844-52. doi:
10.1021/jm900403j
. [PMID: 19445515] - Deniz Ekinci, Sükrü Beydemir. Effect of some analgesics on paraoxonase-1 purified from human serum.
Journal of enzyme inhibition and medicinal chemistry.
2009 Aug; 24(4):1034-9. doi:
10.1080/14756360802608351
. [PMID: 19548782] - Sarathi Kundu, Hirak Chakraborty, Munna Sarkar, Alokmay Datta. Interaction of Oxicam NSAIDs with lipid monolayer: anomalous dependence on drug concentration.
Colloids and surfaces. B, Biointerfaces.
2009 Apr; 70(1):157-61. doi:
10.1016/j.colsurfb.2008.12.017
. [PMID: 19157803] - Haixia Zhang, Hoo-Kyun Choi. Analysis of meloxicam by high-performance liquid chromatography with cloud-point extraction.
Analytical and bioanalytical chemistry.
2008 Nov; 392(5):947-53. doi:
10.1007/s00216-008-2333-0
. [PMID: 18751683] - Mustafa Naziroğlu, Abdulhadi Cihangir Uğuz, Alpaslan Gokçimen, Metin Bülbül, Dilek Ulusoy Karatopuk, Yasin Türker, Celal Cerçi. Tenoxicam modulates antioxidant redox system and lipid peroxidation in rat brain.
Neurochemical research.
2008 Sep; 33(9):1832-7. doi:
10.1007/s11064-008-9643-7
. [PMID: 18340531] - Hirak Chakraborty, Sutapa Mondal, Munna Sarkar. Membrane fusion: a new function of non steroidal anti-inflammatory drugs.
Biophysical chemistry.
2008 Sep; 137(1):28-34. doi:
10.1016/j.bpc.2008.06.007
. [PMID: 18617319] - R Scott Obach, Franco Lombardo, Nigel J Waters. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Drug metabolism and disposition: the biological fate of chemicals.
2008 Jul; 36(7):1385-405. doi:
10.1124/dmd.108.020479
. [PMID: 18426954] - Taekyung Kim, Eunyoung Kang, Inkoo Chun, Hyesun Gwak. Pharmacokinetics of formulated tenoxicam transdermal delivery systems.
The Journal of pharmacy and pharmacology.
2008 Jan; 60(1):135-8. doi:
10.1211/jpp.60.1.0017
. [PMID: 18088513] - Ayten Bilir, Sacit Gulec, Mehmet Turgut, Dilek Cetinkaya, Ayse Erkan, Imran Kurt. Lornoxicam in extracorporeal shock-wave lithotripsy; comparison with tenoxicam and placebo in terms of analgesic consumption.
Scandinavian journal of urology and nephrology.
2008; 42(2):143-7. doi:
10.1080/00365590701225988
. [PMID: 17853036] - J Grifka. [Use of drugs in renal impairment].
Der Internist.
2008 Jan; 49(1):126. doi:
10.1007/s00108-007-2005-8
. [PMID: 18210021] - Iulia Sora, Toma Galaon, Stefan Udrescu, Jean Negru, Victor David, Andrei Medvedovici. Fast RPLC-UV method on short sub-two microns particles packed column for the assay of tenoxicam in plasma samples.
Journal of pharmaceutical and biomedical analysis.
2007 Mar; 43(4):1437-43. doi:
10.1016/j.jpba.2006.11.008
. [PMID: 17142002] - Hye Young Ji, Hye Won Lee, Young Hoon Kim, Dong Won Jeong, Hye Suk Lee. Simultaneous determination of piroxicam, meloxicam and tenoxicam in human plasma by liquid chromatography with tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2005 Nov; 826(1-2):214-9. doi:
10.1016/j.jchromb.2005.08.023
. [PMID: 16169293] - T Yamamoto, H Itoga, Y Kohno, K Nagata, Y Yamazoe. Prediction of oral clearance from in vitro metabolic data using recombinant CYPs: comparison among well-stirred, parallel-tube, distributed and dispersion models.
Xenobiotica; the fate of foreign compounds in biological systems.
2005 Jun; 35(6):627-46. doi:
10.1080/00498250500159371
. [PMID: 16192112] - Salih Ozgocmen, Ozge Ardicoglu, Hasan Erdogan, Ersin Fadillioglu, Huseyin Gudul. In vivo effect of celecoxib and tenoxicam on oxidant/ anti-oxidant status of patients with knee osteoarthritis.
Annals of clinical and laboratory science.
2005; 35(2):137-43. doi:
NULL
. [PMID: 15943176] - I Kyrikou, S K Hadjikakou, D Kovala-Demertzi, K Viras, T Mavromoustakos. Effects of non-steroid anti-inflammatory drugs in membrane bilayers.
Chemistry and physics of lipids.
2004 Dec; 132(2):157-69. doi:
10.1016/j.chemphyslip.2004.06.005
. [PMID: 15555602] - Tamer Akca, Tahsin Colak, Arzu Kanik, Faik Yaylak, Mehmet Caglikulekci, Suha Aydin. The effect of preoperative intravenous use of tenoxicam: a prospective, double-blind, placebo-controlled study.
Journal of investigative surgery : the official journal of the Academy of Surgical Research.
2004 Nov; 17(6):333-8. doi:
10.1080/08941930490524390
. [PMID: 15764501] - Giuseppe Ermondi, Miriam Lorenti, Giulia Caron. Contribution of ionization and lipophilicity to drug binding to albumin: a preliminary step toward biodistribution prediction.
Journal of medicinal chemistry.
2004 Jul; 47(16):3949-61. doi:
10.1021/jm040760a
. [PMID: 15267234] - Rosane Vianna-Jorge, Jamila A Perini, Edson Rondinelli, Guilherme Suarez-Kurtz. CYP2C9 genotypes and the pharmacokinetics of tenoxicam in Brazilians.
Clinical pharmacology and therapeutics.
2004 Jul; 76(1):18-26. doi:
10.1016/j.clpt.2004.03.002
. [PMID: 15229460] - Yasuna Kobayashi, Naomi Ohshiro, Ayumi Tsuchiya, Noriko Kohyama, Masayuki Ohbayashi, Toshinori Yamamoto. Renal transport of organic compounds mediated by mouse organic anion transporter 3 (mOat3): further substrate specificity of mOat3.
Drug metabolism and disposition: the biological fate of chemicals.
2004 May; 32(5):479-83. doi:
10.1124/dmd.32.5.479
. [PMID: 15100168] - Andrew R McKinney, Craig J Suann, Allen M Stenhouse. The detection of piroxicam, tenoxicam and their metabolites in equine urine by electrospray ionisation ion trap mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2004; 18(19):2338-42. doi:
10.1002/rcm.1631
. [PMID: 15384156] - M Makai, E Csányi, Zs Németh, J Pálinkás, I Eros. Structure and drug release of lamellar liquid crystals containing glycerol.
International journal of pharmaceutics.
2003 Apr; 256(1-2):95-107. doi:
10.1016/s0378-5173(03)00066-8
. [PMID: 12695015] - A F Merry, D A Sidebotham, N G Middleton, M V Calder, C S Webster. Tenoxicam 20 mg or 40 mg after thoracotomy: a prospective, randomized, double-blind, placebo-controlled study.
Anaesthesia and intensive care.
2002 Apr; 30(2):160-6. doi:
10.1177/0310057x0203000206
. [PMID: 12002922] - E Cardamakis, A Georgopoulos, A Fotopoulos, G P Sykiotis, A P Pappas, D Lazaris, V A Tzingounis. Clinical experience with Norplant subdermal implant system as long-term contraception during adolescence.
The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception.
2002 Mar; 7(1):36-40. doi:
10.1080/ejc.7.1.36.40
. [PMID: 12041863] - O G Nilsen, K Aasarød, T E Widerøe, T W Guentert. Single- and multiple-dose pharmacokinetics, kidney tolerability and plasma protein binding of tenoxicam in renally impaired patients and healthy volunteers.
Pharmacology & toxicology.
2001 Nov; 89(5):265-72. doi:
10.1034/j.1600-0773.2001.d01-158.x
. [PMID: 11881981] - C V Raghavan, V D Abimon. Intranasal delivery of tenoxicam in rat.
International journal of pharmaceutics.
2001 Jun; 221(1-2):227-9. doi:
10.1016/s0378-5173(01)00635-4
. [PMID: 11397584] - R D Jones, Z Endre, W Miles, R Prankerd, M Chilvers, D Willgoss. Tenoxicam i.v. for major gynaecological surgery--effects on renal function.
Anaesthesia and intensive care.
2000 Oct; 28(5):501-9. doi:
10.1177/0310057x0002800503
. [PMID: 11094664] - Z Kekeç, U Yilmaz, E Sözüer. The effectiveness of tenoxicam vs isosorbide dinitrate plus tenoxicam in the treatment of acute renal colic.
BJU international.
2000 May; 85(7):783-5. doi:
10.1046/j.1464-410x.2000.00613.x
. [PMID: 10792152] - C Kohl, M Steinkellner. Prediction of pharmacokinetic drug/drug interactions from In vitro data: interactions of the nonsteroidal anti-inflammatory drug lornoxicam with oral anticoagulants.
Drug metabolism and disposition: the biological fate of chemicals.
2000 Feb; 28(2):161-8. doi:
NULL
. [PMID: 10640513] - A Marland, P Sarkar, R Leavitt. The elimination profiles of tenoxicam and hydroxytenoxicam in equine urine and serum after a 200-mg oral dose.
Journal of analytical toxicology.
1999 Jul; 23(4):237-41. doi:
10.1093/jat/23.4.237
. [PMID: 10445485] - N N Afifi. Using difference spectrophotometry to study the influence of different ions and buffer systems on drug protein binding.
Drug development and industrial pharmacy.
1999 Jun; 25(6):735-43. doi:
10.1081/ddc-100102233
. [PMID: 10349559] - G M Slaven, R J Walker, M Zacharias, J P Fawcett, B F Hodgson. Tenoxicam does not alter renal function during anaesthesia in normal individuals.
Australian and New Zealand journal of medicine.
1998 Dec; 28(6):772-6. doi:
10.1111/j.1445-5994.1998.tb01552.x
. [PMID: 9972405] - N S al-Waili, K Y Saloom. Intravenous tenoxicam to treat acute renal colic: comparison with buscopan compositum.
JPMA. The Journal of the Pakistan Medical Association.
1998 Dec; 48(12):370-2. doi:
NULL
. [PMID: 10531771] - S Radhofer-Welte, P Dittrich. Determination of the novel non-steroidal anti-inflammatory drug lornoxicam and its main metabolite in plasma and synovial fluid.
Journal of chromatography. B, Biomedical sciences and applications.
1998 Apr; 707(1-2):151-9. doi:
10.1016/s0378-4347(97)00597-5
. [PMID: 9613944] - D W Blake, A R Bjorksten, F C Libreri. Oral tenoxicam for peripheral orthopaedic surgery: a pharmacokinetic study.
Anaesthesia and intensive care.
1997 Apr; 25(2):142-6. doi:
10.1177/0310057x9702500206
. [PMID: 9127656] - R M Maffei Facino, M Carini, L Saibene. Scavenging of free radicals by tenoxicam: a participating mechanism in the antirheumatic/antiinflammatory efficacy of the drug.
Archiv der Pharmazie.
1996 Oct; 329(10):457-63. doi:
10.1002/ardp.19963291007
. [PMID: 8933748] - M Ionac, R Oelkers, K Brune, G Geisslinger, D Bordos. Lymph distribution of different non-steroidal anti-inflammatory drugs assessed by microsurgical cannulation of the thoracic duct in rat.
Romanian journal of internal medicine = Revue roumaine de medecine interne.
1996 Jul; 34(3-4):239-51. doi:
NULL
. [PMID: 9167225] - N S Al-Waili. Intramuscular tenoxicam to treat acute renal colic.
British journal of urology.
1996 Jan; 77(1):15-6. doi:
10.1046/j.1464-410x.1996.08212.x
. [PMID: 8653289] - E Pérez-Tapia, Y Saldaña-Balmori, M Zentella-De Piña, M D Ramíez-González, E Piña-Garza. Piroxicam and tenoxicam effects on ethanol-induced lipid peroxidation in brains of CD-1 male mice.
Proceedings of the Western Pharmacology Society.
1996; 39(?):77-9. doi:
"
. [PMID: 8895975] - I F Troconiz, L G Lopez-Bustamante, D Fos. Tenoxicam pharmacokinetics in rats: a population model.
Journal of pharmaceutical sciences.
1995 Dec; 84(12):1482-7. doi:
10.1002/jps.2600841216
. [PMID: 8748332] - V M Choi, J E Coates, J Chooi, A B Thomson, A S Russell. Small bowel permeability--a variable effect of NSAIDS.
Clinical and investigative medicine. Medecine clinique et experimentale.
1995 Oct; 18(5):357-61. doi:
NULL
. [PMID: 8529318] - C Curry, A M Kelly. Intravenous tenoxicam for the treatment of renal colic.
The New Zealand medical journal.
1995 Jun; 108(1001):229-30. doi:
NULL
. [PMID: 7603654] - D Hartmann, G Stief, M Lingenfelder, C Güzelhan, A K Horsch. Study on the possible interaction between tenoxicam and atenolol in hypertensive patients.
Arzneimittel-Forschung.
1995 Apr; 45(4):494-8. doi:
NULL
. [PMID: 7779149] - J L Mason, G J Hobbs. Simple method for the analysis of tenoxicam in human plasma using high-performance liquid chromatography.
Journal of chromatography. B, Biomedical applications.
1995 Mar; 665(2):410-5. doi:
10.1016/0378-4347(94)00534-c
. [PMID: 7795823] - R C Heintz. Tenoxicam and renal function.
Drug safety.
1995 Feb; 12(2):110-9. doi:
10.2165/00002018-199512020-00004
. [PMID: 7766336] - T W Guentert, T Stebler, L Banken, R Defoin, M Schmitt. Relative bioavailability of oral dosage forms of tenoxicam.
Arzneimittel-Forschung.
1994 Sep; 44(9):1051-4. doi:
NULL
. [PMID: 7986242] - M S Salem, H N Alkaysi, A M Gharaibeh, N M Gharaibeh, A A Badwan. Bioequivalence of two oral dosage forms prepared from different polymorphic modifications of tenoxicam.
Journal of clinical pharmacy and therapeutics.
1994 Jun; 19(3):203-7. doi:
10.1111/j.1365-2710.1994.tb00674.x
. [PMID: 7962225] - G Hasçelik, B Sener, Z Hasçelik. Effect of some anti-inflammatory drugs on human neutrophil chemotaxis.
The Journal of international medical research.
1994 Mar; 22(2):100-6. doi:
10.1177/030006059402200206
. [PMID: 8020636] - O G Nilsen. Clinical pharmacokinetics of tenoxicam.
Clinical pharmacokinetics.
1994 Jan; 26(1):16-43. doi:
10.2165/00003088-199426010-00003
. [PMID: 8137596] - D K Sommers, M van Wyk, J R Snyman. The countering of diazoxide-induced vasodilatation by tenoxicam in normal volunteers.
European journal of clinical pharmacology.
1994; 46(6):569-71. doi:
10.1007/bf00196119
. [PMID: 7995329] - F Brée, S Urien, P Nguyen, J P Tillement, A Steiner, C Vallat-Molliet, B Testa, J Visy, M Simonyi. Human serum albumin conformational changes as induced by tenoxicam and modified by simultaneous diazepam binding.
The Journal of pharmacy and pharmacology.
1993 Dec; 45(12):1050-3. doi:
10.1111/j.2042-7158.1993.tb07179.x
. [PMID: 7908973] - L G Lopez-Bustamante, J I Troconiz, D Fos. Tenoxicam: acute dose-dependent disposition studies in rats.
Journal of pharmaceutical sciences.
1993 Aug; 82(8):851-3. doi:
10.1002/jps.2600820820
. [PMID: 8377127] - T Stebler, T W Guentert. Bioavailability of intramuscularly administered tenoxicam.
Biopharmaceutics & drug disposition.
1993 Aug; 14(6):483-90. doi:
10.1002/bdd.2510140604
. [PMID: 8218966] - M I Múnera-Jaramillo, S Botero-Garcés. Determination of tenoxicam in plasma by high-performance liquid chromatography.
Journal of chromatography.
1993 Jul; 616(2):349-52. doi:
10.1016/0378-4347(93)80407-u
. [PMID: 8376519] - J I Troconiz, L G Lopez-Bustamante, D Fos. High-performance liquid chromatographic analysis of piroxicam and tenoxicam in plasma, blood and buffer solution. Application to pharmacokinetic studies in small laboratory animals.
Arzneimittel-Forschung.
1993 Jun; 43(6):679-81. doi:
NULL
. [PMID: 8352822] - M Del Puppo, M G Kienle, R Ratiglia, D Galimberti, G Acerbi, L Boerci, L Marabini, E Chiesara. Intraocular and plasma kinetics of tenoxicam in rabbits.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie.
1993 Feb; 231(2):115-7. doi:
10.1007/bf00920224
. [PMID: 8444358] - L G Lopez-Bustamante, J I Troconiz, D Fos. Effect of uraemia and anephric state on the pharmacokinetics of tenoxicam in the rat.
The Journal of pharmacy and pharmacology.
1992 Nov; 44(11):898-901. doi:
10.1111/j.2042-7158.1992.tb03232.x
. [PMID: 1361533] - M S al-Ghamdi, F A al-Mohanna, Z H al-Mustafa, I S al-Saeed. The effect of haemodialysis on the pharmacokinetics of tenoxicam in patients with end-stage renal disease.
European journal of clinical pharmacology.
1992; 43(2):197-9. doi:
10.1007/bf01740671
. [PMID: 1425878] - H G Eichler, M Jung, P A Kyrle, M Rotter, A Korn. Absence of interaction between tenoxicam and warfarin.
European journal of clinical pharmacology.
1992; 42(2):227-9. doi:
10.1007/bf00278491
. [PMID: 1618257] - L K Cheung, C Rodrigo. Tenoxicam for pain relief following third molar surgery.
Anesthesia & pain control in dentistry.
1992; 1(4):229-33. doi:
NULL
. [PMID: 1298491] - S Freestone, J A McAuslane, L F Prescott. Effects of tenoxicam on renal function and the disposition of inulin and p-aminohippurate in healthy volunteers and patients with chronic renal failure.
British journal of clinical pharmacology.
1991 Oct; 32(4):495-500. doi:
10.1111/j.1365-2125.1991.tb03937.x
. [PMID: 1958445] - R O Day, K M Williams, S Graham, M Handel. The pharmacokinetics of total and unbound concentrations of tenoxicam in synovial fluid and plasma.
Arthritis and rheumatism.
1991 Jun; 34(6):751-60. doi:
10.1002/art.1780340617
. [PMID: 2053921] - S Colli, S Colombo, E Tremoli, E Stragliotto, S Nicosia. Effects of tenoxicam on superoxide anion formation, beta-glucuronidase release and fMLP binding in human neutrophils: comparison with other NSAIDs.
Pharmacological research.
1991 May; 23(4):367-79. doi:
10.1016/1043-6618(91)90051-x
. [PMID: 1652137] - A Corvetta, R Della Bitta, M M Luchetti, G Pomponio, V Ciuffoletti. Tenoxicam and ketoprofen level monitoring with high performance liquid chromatography in patients affected by rheumatoid arthritis.
Clinical and experimental rheumatology.
1991 Mar; 9(2):143-8. doi:
NULL
. [PMID: 2060161] - B Bannwarth, P Netter, F Lapicque, D Mainard, P Fener, P Gillet, A Gaucher. Tenoxicam concentrations in synovium and joint cartilage in humans.
Agents and actions.
1991 Mar; 32(3-4):295-8. doi:
10.1007/bf01980889
. [PMID: 1862747] - D Hartmann, A Korn, M Komjati, G Heinz, P Haefelfinger, R Defoin, W K Waldhäusl. Lack of effect of tenoxicam on dynamic responses to concurrent oral doses of glucose and glibenclamide.
British journal of clinical pharmacology.
1990 Aug; 30(2):245-52. doi:
10.1111/j.1365-2125.1990.tb03771.x
. [PMID: 2119677] - J L Giovannoni, H Ott, A de Torrenté. [Tenoxicam and renal function. Short-term and long-term prospective studies].
Schweizerische medizinische Wochenschrift.
1990 May; 120(21):793-7. doi:
NULL
. [PMID: 2349462] - H A Bird, A K Clarke, P D Fowler, S Little, M R Podgorski, J Steiner. An assessment of tenoxicam, a nonsteroidal anti-inflammatory drug of long half-life, in patients with impaired renal function suffering from osteoarthritis or rheumatoid arthritis.
Clinical rheumatology.
1989 Dec; 8(4):453-60. doi:
10.1007/bf02032096
. [PMID: 2692947] - K Ghose, A Burch. Measurement of renal functions by double isotope techniques in elderly patients during tenoxicam therapy.
Archives of gerontology and geriatrics.
1989 Sep; 9(2):115-22. doi:
10.1016/0167-4943(89)90032-0
. [PMID: 2589913] - C Crevoisier, P Heizmann, I Forgo, U C Dubach. Plasma tenoxicam concentrations after single and multiple oral doses.
European journal of drug metabolism and pharmacokinetics.
1989 Jan; 14(1):23-7. doi:
10.1007/bf03190838
. [PMID: 2788089] - O H Jensen, O Slot, E Ernst. The fibrinolytic system during short-term treatment with tenoxicam.
Current medical research and opinion.
1989; 11(8):518-22. doi:
10.1185/03007998909110463
. [PMID: 2805772] - M Schmitt, T W Guentert. Effect of age on the pharmacokinetics of tenoxicam in comparison to other non-steroidal anti-inflammatory drugs (NSAIDs).
Scandinavian journal of rheumatology. Supplement.
1989; 80(?):86-9. doi:
10.3109/03009748909103719
. [PMID: 2688082] - F Bree, P Nguyen, S Urien, P Riant, E Albengres, H Fenner, J P Tillement. Blood distribution of tenoxicam in humans: a particular HSA drug interaction.
Fundamental & clinical pharmacology.
1989; 3(3):267-79. doi:
10.1111/j.1472-8206.1989.tb00456.x
. [PMID: 2767607] - W Enz, F Jeunet. Tenoxicam milk formulation in the treatment of rheumatic conditions.
Scandinavian journal of rheumatology. Supplement.
1989; 80(?):54-8. doi:
10.3109/03009748909103713
. [PMID: 2595343] - F Jeunet, W Enz, T Guentert. Tenoxicam used as a parenteral formulation for acute pain in rheumatic conditions.
Scandinavian journal of rheumatology. Supplement.
1989; 80(?):59-61. doi:
10.3109/03009748909103714
. [PMID: 2595344] - C Crevoisier, P Y Zaugg, P Heizmann, J Meyer. Influence of liver cirrhosis upon the pharmacokinetics of tenoxicam.
International journal of clinical pharmacology research.
1989; 9(5):327-34. doi:
NULL
. [PMID: 2625372] - R O Day, P D Paull, S Lam, B R Swanson, K M Williams, D N Wade. The effect of concurrent aspirin upon plasma concentrations of tenoxicam.
British journal of clinical pharmacology.
1988 Oct; 26(4):455-62. doi:
10.1111/j.1365-2125.1988.tb03405.x
. [PMID: 3190995] - A Kinawi, D Siebler. [The binding of oxicam derivatives to human serum albumin].
Arzneimittel-Forschung.
1988 Aug; 38(8):1089-92. doi:
NULL
. [PMID: 3264167] - J S Dixon, R Bojar, H A Bird. Renal impairment in relation to non-steroidal anti-inflammatory drugs.
Annals of the rheumatic diseases.
1988 Mar; 47(3):260. doi:
10.1136/ard.47.3.260
. [PMID: 3258505] - P H Hinderling, D Hartmann, C Crevoisier, U Moser, P Heizmann. Integrated plasma and synovial fluid pharmacokinetics of tenoxicam in patients with rheumatoid arthritis and osteoarthritis: factors determining the synovial fluid/plasma distribution ratio.
Therapeutic drug monitoring.
1988; 10(3):250-60. doi:
10.1097/00007691-198803000-00002
. [PMID: 3262939] - O G Nilsen, R A Walstad, M Eckert, P Heizmann, A Bückert, T Am, I Løge, J Unnvik, E Thue. Single and multiple dose pharmacokinetics of tenoxicam in the elderly.
European journal of clinical pharmacology.
1988; 35(5):563-6. doi:
10.1007/bf00558254
. [PMID: 3266152] - R O Day, S Lam, P Paull, D Wade. Effect of food and various antacids on the absorption of tenoxicam.
British journal of clinical pharmacology.
1987 Sep; 24(3):323-8. doi:
10.1111/j.1365-2125.1987.tb03176.x
. [PMID: 3499163]