Febantel (BioDeep_00000014959)

 

Secondary id: BioDeep_00000178996


代谢物信息卡片


Febantel

化学式: C20H22N4O6S (446.1259992)
中文名称: 非班太尔
谱图信息: 最多检出来源 Mus musculus(blood) 50%

分子结构信息

SMILES: COCC(=O)NC1=C(C=CC(=C1)SC2=CC=CC=C2)N=C(NC(=O)OC)NC(=O)OC
InChI: InChI=1S/C20H22N4O6S/c1-28-12-17(25)21-16-11-14(31-13-7-5-4-6-8-13)9-10-15(16)22-18(23-19(26)29-2)24-20(27)30-3/h4-11H,12H2,1-3H3,(H,21,25)(H2,22,23,24,26,27)

描述信息

D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics
C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent

同义名列表

1 个代谢物同义名

Febantel



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ž Vienažindienė, D E Joekel, R Schaper, P Deplazes, M Šarkūnas. Longitudinal study for anthelmintic efficacy against intestinal helminths in naturally exposed Lithuanian village dogs: critical analysis of feasibility and limitations. Parasitology research. 2018 May; 117(5):1581-1590. doi: 10.1007/s00436-018-5843-5. [PMID: 29574514]
  • Mario Moron-Soto, Lilia Gutierrez, Héctor Sumano, Graciela Tapia, Yazmin Alcala-Canto. Efficacy of nitazoxanide to treat natural Giardia infections in dogs. Parasites & vectors. 2017 01; 10(1):52. doi: 10.1186/s13071-017-1998-7. [PMID: 28143543]
  • Gabriella Klausz, Éva Keller, Zoltán Sára, Péter Székely-Körmöczy, Péter Laczay, Kornélia Ary, Péter Sótonyi, Kálmán Róna. Simultaneous determination of praziquantel, pyrantel embonate, febantel and its active metabolites, oxfendazole and fenbendazole, in dog plasma by liquid chromatography/mass spectrometry. Biomedical chromatography : BMC. 2015 Dec; 29(12):1859-65. doi: 10.1002/bmc.3507. [PMID: 26104502]
  • Yu Tamura, Hiroshi Ohta, Takuya Kashiide, Jun Matsumoto, Tatsuya Sakurai, Nozomu Yokoyama, Keitaro Morishita, Kensuke Nakamura, Masahiro Yamasaki, Mitsuyoshi Takiguchi. Case report: protein-losing enteropathy caused by Mesocestoides vogae (syn. M. corti) in a dog. Veterinary parasitology. 2014 Sep; 205(1-2):412-5. doi: 10.1016/j.vetpar.2014.07.027. [PMID: 25129334]
  • W De Jaeghere, B G De Geest, J Van Bocxlaer, J P Remon, C Vervaet, A Antunes da Fonseca. Formulation of poorly water-soluble drugs via coacervation--a pilot study using febantel. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2013 Nov; 85(3 Pt B):930-5. doi: 10.1016/j.ejpb.2013.07.006. [PMID: 23872178]
  • Piyanan Taweethavonsawat, Sudchit Chungpivat, Pakkawan Satranarakun, Rebecca J Traub, Roland Schaper. Efficacy of a combination product containing pyrantel, febantel and praziquantel (Drontal Plus Flavour, Bayer Animal Health) against experimental infection with the hookworm Ancylostoma ceylanicum in dogs. Parasitology research. 2010 Jan; 106(2):533-7. doi: 10.1007/s00436-009-1665-9. [PMID: 19911198]
  • Eva Osterman Lind, Dan Christensson. Anthelmintic efficacy on Parascaris equorum in foals on Swedish studs. Acta veterinaria Scandinavica. 2009 Nov; 51(?):45. doi: 10.1186/1751-0147-51-45. [PMID: 19930608]
  • Dwight D Bowman, Janice L Liotta, Michael Ulrich, Sam D Charles, Josef Heine, Roland Schaper. Treatment of naturally occurring, asymptomatic Giardia sp. in dogs with Drontal Plus flavour tablets. Parasitology research. 2009 Aug; 105 Suppl 1(?):S125-34. doi: 10.1007/s00436-009-1503-0. [PMID: 19575233]
  • Donato Traversa, Barbara Paoletti, Domenico Otranto, James Miller. First report of multiple drug resistance in trichostrongyles affecting sheep under field conditions in Italy. Parasitology research. 2007 Nov; 101(6):1713-6. doi: 10.1007/s00436-007-0707-4. [PMID: 17712570]
  • R Schenker, R Cody, G Strehlau, D Alexander, P Junquera. Comparative effects of milbemycin oxime-based and febantel-pyrantel embonate-based anthelmintic tablets on Toxocara canis egg shedding in naturally infected pups. Veterinary parasitology. 2006 Apr; 137(3-4):369-73. doi: 10.1016/j.vetpar.2006.01.023. [PMID: 16490320]
  • H Sager, Ch Steiner Moret, F Grimm, P Deplazes, M G Doherr, B Gottstein. Coprological study on intestinal helminths in Swiss dogs: temporal aspects of anthelminthic treatment. Parasitology research. 2006 Mar; 98(4):333-8. doi: 10.1007/s00436-005-0093-8. [PMID: 16374614]
  • Andrea V Scorza, Steven V Radecki, Michael R Lappin. Efficacy of a combination of febantel, pyrantel, and praziquantel for the treatment of kittens experimentally infected with Giardia species. Journal of feline medicine and surgery. 2006 Feb; 8(1):7-13. doi: 10.1016/j.jfms.2005.04.004. [PMID: 16011902]
  • Patricia A Payne, Robert K Ridley, Michael W Dryden, Christine Bathgate, George A Milliken, Patricia W Stewart. Efficacy of a combination febantel-praziquantel-pyrantel product, with or without vaccination with a commercial Giardia vaccine, for treatment of dogs with naturally occurring giardiasis. Journal of the American Veterinary Medical Association. 2002 Feb; 220(3):330-3. doi: 10.2460/javma.2002.220.330. [PMID: 11829263]
  • A W Demiaszkiewicz, A Malczewski, J Lachowicz. [Attempt of deworming of red and fallow deer in deer farm with rintal premix]. Wiadomosci parazytologiczne. 1999; 45(4):489-93. doi: NULL. [PMID: 16888990]
  • S C Barr, D D Bowman, M F Frongillo, S L Joseph. Efficacy of a drug combination of praziquantel, pyrantel pamoate, and febantel against giardiasis in dogs. American journal of veterinary research. 1998 Sep; 59(9):1134-6. doi: NULL. [PMID: 9736391]
  • Z Ben-Zvi, E Gussarsky, C van Creveld, R Yagil. The bioavailability of febantel in dehydrated camels. Journal of veterinary pharmacology and therapeutics. 1996 Aug; 19(4):288-94. doi: 10.1111/j.1365-2885.1996.tb00051.x. [PMID: 8866457]
  • J Landuyt, M Debackere, J Vercruysse, Q McKellar. The influence of a heavy infection with sensitive and resistant strains of Ostertagia circumcincta and with Trichostrongylus colubriformis on the pharmacokinetics of febantel in lambs. Journal of veterinary pharmacology and therapeutics. 1995 Jun; 18(3):180-6. doi: 10.1111/j.1365-2885.1995.tb00576.x. [PMID: 7674453]
  • C Chartier, A Kulo, J Cabaret, I Pors, C Benoit. Individual fluctuations in efficacy of febantel against Muellerius capillaris in goats. Veterinary research. 1995; 26(2):116-23. doi: . [PMID: 7735302]
  • A Kulo, C Chartier, J Cabaret. Between goat-farm biological variability of the nematode Muellerius capillaris first-stage larvea. Influence of anthelmintic treatment. Parasite (Paris, France). 1994 Mar; 1(1):65-70. doi: 10.1051/parasite/1994011065. [PMID: 9140473]
  • A Kulo, C Chartier, J Cabaret. Variability in susceptibility to anthelmintics of the lungworm Muellerius capillaris first-stage larvae. Relationship to dairy-goat farms and previous exposure to febantel treatment. Veterinary research. 1994; 25(6):537-43. doi: . [PMID: 7889035]
  • M Debackere, J Landuyt, J Vercruysse, Q McKellar. The influence of Ostertagia circumcincta and Trichostrongylus colubriformis infections on the pharmacokinetics of febantel in lambs. Journal of veterinary pharmacology and therapeutics. 1993 Sep; 16(3):261-74. doi: 10.1111/j.1365-2885.1993.tb00173.x. [PMID: 8230397]
  • J Landuyt, M Debackere, F Delbeke, Q McKellar. A high performance liquid chromatographic method for the determination of febantel and its major metabolites in lamb plasma. Biomedical chromatography : BMC. 1993 Mar; 7(2):78-81. doi: 10.1002/bmc.1130070206. [PMID: 8485378]
  • E C Greiner, D G Brenner, D D Cox, D L Heaton-Jones. Comparison of febantel tablets and Vercom paste against gastrointestinal nematodes of dogs. Veterinary parasitology. 1992 Feb; 41(1-2):151-6. doi: 10.1016/0304-4017(92)90018-5. [PMID: 1561756]
  • T J Hopkins. Efficacy of a tablet containing pyrantel embonate, febantel and praziquantel against T canis in dogs. The Veterinary record. 1991 Apr; 128(14):331. doi: 10.1136/vr.128.14.331. [PMID: 2063526]
  • D A Christensson, H Raue, S Bernstad. A field evaluation of treatment with febantel for the control of Toxocara canis in pups. Veterinary parasitology. 1991 Jan; 38(1):41-7. doi: 10.1016/0304-4017(91)90006-h. [PMID: 2024429]
  • C Bauer. Comparative efficacy of praziquantel, albendazole, febantel and oxfendazole against Moniezia expansa. The Veterinary record. 1990 Oct; 127(14):353-4. doi: NULL. [PMID: 2260242]
  • J C de Rond, R de Jong, J H Boon, B Brouwer. Influence of gastro-intestinal nematodes on the productivity of dairy cattle in the wet highlands of Sri Lanka. Tropical animal health and production. 1990 May; 22(2):135-43. doi: 10.1007/bf02239843. [PMID: 2371753]
  • J A Stuedemann, H Ciordia, R G Arther. Anthelmintic efficacy of febantel paste in naturally infected calves. Veterinary parasitology. 1990 Apr; 35(4):341-7. doi: 10.1016/0304-4017(90)90138-2. [PMID: 2353426]
  • B L Blagburn, C M Hendrix, L A Hanrahan, D S Lindsay, R G Arther, J W Drane. Controlled dosage titration of febantel paste in naturally parasitized cattle. American journal of veterinary research. 1989 Sep; 50(9):1574-7. doi: NULL. [PMID: 2802334]
  • J C Williams, K S Marbury, C S Eddi, E R Willis, D G Luther. Efficacy of febantel against abomasal nematodes and lungworms in cattle. American journal of veterinary research. 1988 Dec; 49(12):2085-9. doi: NULL. [PMID: 2977070]
  • C H Courtney, J K Shearer, Q Y Zeng, R G Arther. Efficacy of febantel paste against naturally acquired gastrointestinal nematodes of cattle. Journal of the American Veterinary Medical Association. 1988 Sep; 193(6):665-7. doi: NULL. [PMID: 3192439]
  • E P Hoberg, G L Zimmerman, L G Rickard, D J Schons. Efficacy of febantel against naturally acquired gastrointestinal nematodes in calves, and recognition of Oesophagostomum venulosum in Oregon cattle. American journal of veterinary research. 1988 Sep; 49(9):1540-2. doi: NULL. [PMID: 3223663]
  • R Reinemeyer, J E Henton. Observations on equine strongyle control in southern temperate USA. Equine veterinary journal. 1987 Nov; 19(6):505-8. doi: 10.1111/j.2042-3306.1987.tb02659.x. [PMID: 3504760]
  • H J Bürger, C Bauer. Efficacy of four anthelmintics against benzimidazole-resistant cyathostomes of horses. The Veterinary record. 1987 Mar; 120(13):293-6. doi: 10.1136/vr.120.13.293. [PMID: 3590562]
  • P Delatour, M P Tiberghien, F Garnier, E Benoît. Comparative pharmacokinetics of febantel and its metabolites in sheep and cattle. American journal of veterinary research. 1985 Jun; 46(6):1399-402. doi: NULL. [PMID: 4026020]
  • J A DiPietro, K S Todd, T F Lock, V Reuter-Dallman. Evaluation of febantel used concurrently with piperazine citrate in horses. Journal of the American Veterinary Medical Association. 1985 Feb; 186(3):262-4. doi: NULL. [PMID: 3972687]
  • P Delatour, M P Tiberghien, S Besse. An HPLC procedure for the quantification of five metabolites of febantel in sheep serum. Journal of veterinary pharmacology and therapeutics. 1983 Sep; 6(3):233-5. doi: 10.1111/j.1365-2885.1983.tb00469.x. [PMID: 6632081]
  • H Ciordia, H C McCampbell, J A Stuedemann. Anthelmintic efficacy of febantel against gastrointestinal helminths in calves. American journal of veterinary research. 1982 Dec; 43(12):2248-9. doi: NULL. [PMID: 7165174]
  • R P Herd, T B Miller, A A Gabel. A field evaluation of pro-benzimidazole, benzimidazole, and non-benzimidazole anthelmintics in horses. Journal of the American Veterinary Medical Association. 1981 Oct; 179(7):686-91. doi: NULL. [PMID: 7341582]
  • J H Drudge, E T Lyons, S C Tolliver. Critical tests of the anthelmintic febantel in the horse: activity of a paste formulation alone or with a trichlorfon paste. American journal of veterinary research. 1978 Sep; 39(9):1419-21. doi: NULL. [PMID: 697152]