Pyriproxyfen (BioDeep_00000014881)

 

Secondary id: BioDeep_00000271363

human metabolite blood metabolite


代谢物信息卡片


4-Phenoxyphenyl (RS)-2-(2-pyridyloxy)propyl ether

化学式: C20H19NO3 (321.1364864000001)
中文名称: 甲醇中吡丙醚溶液
谱图信息: 最多检出来源 Homo sapiens(blood) 3.49%

分子结构信息

SMILES: CC(COC1=CC=C(C=C1)OC2=CC=CC=C2)OC3=CC=CC=N3
InChI: InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3

描述信息

CONFIDENCE standard compound; INTERNAL_ID 235; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10357; ORIGINAL_PRECURSOR_SCAN_NO 10352
CONFIDENCE standard compound; INTERNAL_ID 235; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10314; ORIGINAL_PRECURSOR_SCAN_NO 10312
CONFIDENCE standard compound; INTERNAL_ID 235; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10325; ORIGINAL_PRECURSOR_SCAN_NO 10324
CONFIDENCE standard compound; INTERNAL_ID 235; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10287; ORIGINAL_PRECURSOR_SCAN_NO 10284
CONFIDENCE standard compound; INTERNAL_ID 235; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10340; ORIGINAL_PRECURSOR_SCAN_NO 10338
CONFIDENCE standard compound; INTERNAL_ID 235; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10362; ORIGINAL_PRECURSOR_SCAN_NO 10360
CONFIDENCE standard compound; INTERNAL_ID 2633
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals

同义名列表

8 个代谢物同义名

4-Phenoxyphenyl (RS)-2-(2-pyridyloxy)propyl ether; 2-{[1-(4-phenoxyphenoxy)propan-2-yl]oxy}pyridine; 2-(1-Methyl-2-(4-phenoxyphenoxy)ethoxy)pyridine; Pyriproxyfen, (R)-isomer; Pyriproxyfen, (S)-isomer; Pyriproxyfen; Juvinal; Cyclio



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Naeem Iqbal, Nauman Sadiq, Muhammad Nadir Naqqash, Muhammad Usman, Hafiz Azhar Ali Khan, Allah Ditta Abid, Muhammad Sohail Shahzad. Transgenerational effects of pyriproxyfen in a field strain of Musca domestica L. (Diptera: Muscidae). PloS one. 2024; 19(3):e0300922. doi: 10.1371/journal.pone.0300922. [PMID: 38517921]
  • Guoli Li, Yizhe Li, Chunhui He, Yuting Wei, Kunpei Cai, Qingyu Lu, Xuebin Liu, Yizhou Zhu, Kaizun Xu. The promoting effects of pyriproxyfen on autophagy and apoptosis in silk glands of non-target insect silkworm, Bombyx mori. Pesticide biochemistry and physiology. 2023 Nov; 196(?):105586. doi: 10.1016/j.pestbp.2023.105586. [PMID: 37945223]
  • Kaizun Xu, Huangli Lan, Chunhui He, Yuting Wei, Qingyu Lu, Kunpei Cai, Dongliang Yu, Xingcan Yin, Yizhe Li, Jiachen Lv. Toxicological effects of trace amounts of pyriproxyfen on the midgut of non-target insect silkworm. Pesticide biochemistry and physiology. 2022 Nov; 188(?):105266. doi: 10.1016/j.pestbp.2022.105266. [PMID: 36464371]
  • Sri Jyosthsna Kancharlapalli, Kaz Surowiec, Scott D Longing, Corey L Brelsfoard. Nectar Source and Pollinator Cross Contamination and Persistence of Pyriproxyfen Associated with the Use of Autodissemination Techniques for Mosquito Control. Journal of the American Mosquito Control Association. 2022 09; 38(3):175-187. doi: 10.2987/22-7075. [PMID: 35839273]
  • Hongxia Li, Qing Zhong, Min Wang, Fengjian Luo, Xinru Wang, Li Zhou, Xinzhong Zhang. Residue degradation, transfer and risk assessment of pyriproxyfen and its metabolites from tea garden to cup by ultra performance liquid chromatography tandem mass spectrometry. Journal of the science of food and agriculture. 2022 Aug; 102(10):3983-3993. doi: 10.1002/jsfa.11746. [PMID: 34994973]
  • Zhou Tong, Tingmi Yang, Mingna Sun, Xu Dong, Yue Chu, Dandan Meng, Mei Wang, Tongchun Gao, Jinsheng Duan. Systemic assessment of the chiral insecticide pyriproxyfen in a citrus nectar source system: Stereoselective degradation, biological effect and exposure risk. Pest management science. 2022 Jul; 78(7):3012-3018. doi: 10.1002/ps.6926. [PMID: 35426212]
  • Reema Chaudhary, Rakhi Singh, Monica Singh, Navin Kumar Mogha, Premlata Kumari, Gaurao Paliwal, Prabal Pratap Singh, Mukul Das. LC-MS/MS method for the simultaneous quantification of pyriproxyfen and bifenthrin and their dissipation kinetics under field conditions in chili and brinjal. Journal of food science. 2022 Mar; 87(3):1331-1341. doi: 10.1111/1750-3841.16070. [PMID: 35170049]
  • Elton Luiz Scudeler, Shelly Favorito de Carvalho, Ana Silvia Gimenes Garcia, Marilucia Santorum, Carlos Roberto Padovani, Daniela Carvalho Dos Santos. Midgut and fat body: Multisystemic action of pyriproxyfen on non-target organism Ceraeochrysa claveri (Neuroptera: Chrysopidae). Environmental pollution (Barking, Essex : 1987). 2022 Jan; 293(?):118580. doi: 10.1016/j.envpol.2021.118580. [PMID: 34843850]
  • Xuwen Li, Sumaira Naseem, Riaz Hussain, Abdul Ghaffar, Kun Li, Ahrar Khan. Evaluation of DNA Damage, Biomarkers of Oxidative Stress, and Status of Antioxidant Enzymes in Freshwater Fish (Labeo rohita) Exposed to Pyriproxyfen. Oxidative medicine and cellular longevity. 2022; 2022(?):5859266. doi: 10.1155/2022/5859266. [PMID: 35720182]
  • Guoli Li, Huangli Lan, Qingyu Lu, Chunhui He, Yuting Wei, Danmei Mo, Dacai Qu, Kaizun Xu. The JH-Met2-Kr-h1 pathway is involved in pyriproxyfen-induced defects of metamorphosis and silk protein synthesis in silkworms, Bombyx mori. Pesticide biochemistry and physiology. 2021 Nov; 179(?):104980. doi: 10.1016/j.pestbp.2021.104980. [PMID: 34802530]
  • Gabriela F de Oliveira, Viviane S Magalhães, Melina Cardilo Campos Alves, Ingrid Lins Raquel de Jesus, Monique Taveira Medeiros, Bruno de Toledo Gomes, Simone Bizerra Calado, Raphael Comissário de Melo, Yara P Cid, Fábio B Scott. Evaluation of pyriproxyfen in cattle by oral treatment: An alternative to control Haematobia irritans. Veterinary parasitology. 2021 Nov; 299(?):109565. doi: 10.1016/j.vetpar.2021.109565. [PMID: 34507202]
  • Sri Jyosthsna Kancharlapalli, Cameron J Crabtree, Kaz Surowiec, Scott D Longing, Corey L Brelsfoard. Indirect transfer of pyriproxyfen to European honeybees via an autodissemination approach. PLoS neglected tropical diseases. 2021 10; 15(10):e0009824. doi: 10.1371/journal.pntd.0009824. [PMID: 34648501]
  • Chi Wu, Xingang Liu, Mingyuan He, Fengshou Dong, Xiaohu Wu, Jun Xu, Yongquan Zheng. Quantitative determination of pyriproxyfen and its metabolite residues in bee products of China using a modified QuEChERS approach with UPLC-MS/MS. Ecotoxicology and environmental safety. 2021 Sep; 220(?):112388. doi: 10.1016/j.ecoenv.2021.112388. [PMID: 34091183]
  • Wilson R Valbon, Eduardo Hatano, Nádylla R X Oliveira, Álvaro D Ataíde, Maria Júlia M Corrêa, Sabriny F Gomes, Gustavo F Martins, Khalid Haddi, Elson S Alvarenga, Eugênio E Oliveira. Detrimental effects of pyriproxyfen on the detoxification and abilities of Belostoma anurum to prey upon Aedes aegypti larvae. Environmental pollution (Barking, Essex : 1987). 2021 Sep; 284(?):117130. doi: 10.1016/j.envpol.2021.117130. [PMID: 33910136]
  • Paulo S G Cremonez, Heather G Marco, Avacir C Andrello, Pedro M O J Neves, Daniela O Pinheiro. The effect of pyriproxyfen on the concentration of circulating metabolic fuel molecules and chemical elements in the hemolymph of Acraea horta L. (Lepidoptera: Nymphalidae): A quantitative analysis. Pesticide biochemistry and physiology. 2021 Aug; 177(?):104907. doi: 10.1016/j.pestbp.2021.104907. [PMID: 34301350]
  • Tarsis Tamar Pereira Silva, Aurea Vieira Teixeira, Alexandre de Almeida E Silva. Pyriproxyfen Ingested With Attractive Toxic Sugar Baits Is Carried by the Feces and Reduces the Reproductive Potential of Adult Female Aedes aegypti (Diptera: Culicidae). Journal of medical entomology. 2021 05; 58(3):1264-1269. doi: 10.1093/jme/tjaa265. [PMID: 33511413]
  • Afifa Naeem, Faisal Hafeez, Ayesha Iftikhar, Muhammad Waaiz, Ali Güncan, Farman Ullah, Farhan Mahmood Shah. Laboratory induced selection of pyriproxyfen resistance in Oxycarenus hyalinipennis Costa (Hemiptera: Lygaeidae): Cross-resistance potential, realized heritability, and fitness costs determination using age-stage, two-sex life table. Chemosphere. 2021 Apr; 269(?):129367. doi: 10.1016/j.chemosphere.2020.129367. [PMID: 33388567]
  • Vanessa Staldoni de Oliveira, Allisson Jhonatan Gomes Castro, Katiuska Marins, Ana Karla Bittencourt Mendes, Gabriel Adan Araújo Leite, Ariane Zamoner, Glen Van Der Kraak, Fátima Regina Mena Barreto Silva. Pyriproxyfen induces intracellular calcium overload and alters antioxidant defenses in Danio rerio testis that may influence ongoing spermatogenesis. Environmental pollution (Barking, Essex : 1987). 2021 Feb; 270(?):116055. doi: 10.1016/j.envpol.2020.116055. [PMID: 33272804]
  • Muhammad Dildar Gogi, Ali Hassan Syed, Bilal Atta, Muhammad Sufyan, Muhammad Jalal Arif, Muhammad Arshad, Ahmad Nawaz, Muhammad Ahsan Khan, Adeel Mukhtar, Oscar Emanuel Liburd. Efficacy of biorational insecticides against Bemisia tabaci (Genn.) and their selectivity for its parasitoid Encarsia formosa Gahan on Bt cotton. Scientific reports. 2021 01; 11(1):2101. doi: 10.1038/s41598-021-81585-x. [PMID: 33483556]
  • Kannan Maharajan, Sellamani Muthulakshmi, Chinnannan Karthik, Bojan Nataraj, Kanthan Nambirajan, Devan Hemalatha, Swaminathan Jiji, Krishna Kadirvelu, Ke-Chun Liu, Mathan Ramesh. Pyriproxyfen induced impairment of reproductive endocrine homeostasis and gonadal histopathology in zebrafish (Danio rerio) by altered expression of hypothalamus-pituitary-gonadal (HPG) axis genes. The Science of the total environment. 2020 Sep; 735(?):139496. doi: 10.1016/j.scitotenv.2020.139496. [PMID: 32480152]
  • Ayesha Iftikhar, Faisal Hafeez, Muhammad Hafeez, Muhammad Farooq, Muhammad Asif Aziz, Muhammad Sohaib, Afifa Naeem, Yaobin Lu. Sublethal effects of a juvenile hormone analog, Pyriproxyfen on demographic parameters of non-target predator, Hippodamia convergens Guerin-Meneville (Coleoptera: Coccinellidae). Ecotoxicology (London, England). 2020 Sep; 29(7):1017-1028. doi: 10.1007/s10646-020-02159-7. [PMID: 31955283]
  • Paula A Faria Waziry, Aarti Raja, Chloe Salmon, Nathalia Aldana, Sruthi Damodar, Andre Rinaldi Fukushima, Bindu S Mayi. Impact of pyriproxyfen on virus behavior: implications for pesticide-induced virulence and mechanism of transmission. Virology journal. 2020 07; 17(1):93. doi: 10.1186/s12985-020-01378-y. [PMID: 32631404]
  • Amna Shahid, Marryam Saher. Repeated exposure of pyriproxyfen to pregnant female mice causes developmental abnormalities in prenatal pups. Environmental science and pollution research international. 2020 Jul; 27(21):26998-27009. doi: 10.1007/s11356-020-08656-w. [PMID: 32382916]
  • Masumeh Ziaee, Asgar Babamir-Satehi. Characterization of Nanostructured Silica as Carrier for Insecticides Deltamethrin, Pyriproxyfen, and Chlorpyrifos and Testing the Insecticidal Efficacy Against Trogoderma granarium (Coleoptera: Dermestidae) Larvae. Journal of economic entomology. 2020 02; 113(1):511-517. doi: 10.1093/jee/toz264. [PMID: 31634405]
  • Inmaculada Fuertes, Rita Jordão, Benjamín Piña, Carlos Barata. Time-dependent transcriptomic responses of Daphnia magna exposed to metabolic disruptors that enhanced storage lipid accumulation. Environmental pollution (Barking, Essex : 1987). 2019 Jun; 249(?):99-108. doi: 10.1016/j.envpol.2019.02.102. [PMID: 30884398]
  • I Munir, A Bano, M Faisal. Impact of phosphate solubilizing bacteria on wheat (Triticum aestivum ) in the presence of pesticides. Brazilian journal of biology = Revista brasleira de biologia. 2019 Jan; 79(1):29-37. doi: 10.1590/1519-6984.172213. [PMID: 30726453]
  • Inmaculada Fuertes, Rita Jordão, Josefina Casas, Carlos Barata. Allocation of glycerolipids and glycerophospholipids from adults to eggs in Daphnia magna: Perturbations by compounds that enhance lipid droplet accumulation. Environmental pollution (Barking, Essex : 1987). 2018 Nov; 242(Pt B):1702-1710. doi: 10.1016/j.envpol.2018.07.102. [PMID: 30064873]
  • Kannan Maharajan, Sellamani Muthulakshmi, Bojan Nataraj, Mathan Ramesh, Krishna Kadirvelu. Toxicity assessment of pyriproxyfen in vertebrate model zebrafish embryos (Danio rerio): A multi biomarker study. Aquatic toxicology (Amsterdam, Netherlands). 2018 Mar; 196(?):132-145. doi: 10.1016/j.aquatox.2018.01.010. [PMID: 29407799]
  • Pengqiang Du, Xiaohu Wu, Jun Xu, Fengshou Dong, Yingchun Shi, Yuanbo Li, Xingang Liu, Yongquan Zheng. Different residue behaviors of four pesticides in mushroom using two different application methods. Environmental science and pollution research international. 2018 Mar; 25(9):8377-8387. doi: 10.1007/s11356-017-1142-4. [PMID: 29307062]
  • Odile Crosaz, Silvia Bonati, Amaury Briand, Elodie Chapelle, Noëlle Cochet-Faivre, Diane Ka, Céline Darmon-Hadjaje, Marie Varloud, Jacques Guillot. Usefulness of a topical combination of dinotefuran and pyriproxyfen for long-term control of clinical signs of allergic dermatitis in privately-owned cats in Ile-de-France region. Parasites & vectors. 2017 Aug; 10(1):392. doi: 10.1186/s13071-017-2335-x. [PMID: 28830567]
  • Pengqiang Du, Xiaohu Wu, Hairong He, Ying Zhang, Jun Xu, Fengshou Dong, Yongquan Zheng, Xingang Liu. Evaluation of the safe use and dietary risk of beta-cypermethrin, pyriproxyfen, avermectin, diflubenzuron and chlorothalonil in button mushroom. Scientific reports. 2017 08; 7(1):8694. doi: 10.1038/s41598-017-07860-y. [PMID: 28821721]
  • Jodi M Scott, Kelly E Seeger, Jennifer Gibson-Corrado, Gunter C Muller, Rui-De Xue. Attractive Toxic Sugar Bait (ATSB) Mixed With Pyriproxyfen for Control of Larval Aedes albopictus (Diptera: Culicidae) Through Fecal Deposits of Adult Mosquitoes. Journal of medical entomology. 2017 01; 54(1):236-238. doi: 10.1093/jme/tjw133. [PMID: 28082652]
  • Q L Wang, T-X Liu. Effects of Three Insect Growth Regulators on Encarsia formosa (Hymenoptera: Aphelinidae), an Endoparasitoid of Bemisia tabaci (Hemiptera: Aleyrodidae). Journal of economic entomology. 2016 Dec; 109(6):2290-2297. doi: 10.1093/jee/tow216. [PMID: 27744284]
  • Fangyuan Zhou, Guodong Zhu, Haipeng Zhao, Zheng Wang, Ming Xue, Xianxian Li, Huaqiang Xu, Xiaodan Ma, Yanyan Liu. Sterilization Effects of Adult-targeted Baits Containing Insect Growth Regulators on Delia antiqua. Scientific reports. 2016 09; 6(?):32855. doi: 10.1038/srep32855. [PMID: 27619006]
  • Frédéric Darriet. An anti-mosquito mixture for domestic use, combining a fertiliser and a chemical or biological larvicide. Pest management science. 2016 Jul; 72(7):1340-5. doi: 10.1002/ps.4157. [PMID: 26414239]
  • Rita Jordão, Elba Garreta, Bruno Campos, Marco F L Lemos, Amadeu M V M Soares, Romà Tauler, Carlos Barata. Compounds altering fat storage in Daphnia magna. The Science of the total environment. 2016 Mar; 545-546(?):127-36. doi: 10.1016/j.scitotenv.2015.12.097. [PMID: 26747981]
  • Kai-Yun Fu, Wen-Chao Guo, Tursun Ahmat, Guo-Qing Li. Knockdown of a nutrient amino acid transporter gene LdNAT1 reduces free neutral amino acid contents and impairs Leptinotarsa decemlineata pupation. Scientific reports. 2015 Dec; 5(?):18124. doi: 10.1038/srep18124. [PMID: 26657797]
  • Ralf Nauen, Katharina Wölfel, Bettina Lueke, Antonis Myridakis, Dimitra Tsakireli, Emmanouil Roditakis, Anastasia Tsagkarakou, Euripides Stephanou, John Vontas. Development of a lateral flow test to detect metabolic resistance in Bemisia tabaci mediated by CYP6CM1, a cytochrome P450 with broad spectrum catalytic efficiency. Pesticide biochemistry and physiology. 2015 Jun; 121(?):3-11. doi: 10.1016/j.pestbp.2014.12.023. [PMID: 26047106]
  • Petra Bizikova, Karen A Moriello, Keith E Linder, Leslie Sauber. Dinotefuran/pyriproxyfen/permethrin pemphigus-like drug reaction in three dogs. Veterinary dermatology. 2015 Jun; 26(3):206-8, e45. doi: 10.1111/vde.12202. [PMID: 25758668]
  • Seok-Hee Lee, Hyun-Woo Oh, Ying Fang, Saes-Byeol An, Doo-Sang Park, Hyuk-Hwan Song, Sei-Ryang Oh, Soo-Young Kim, Seonghyun Kim, Namjung Kim, Alexander S Raikhel, Yeon Ho Je, Sang Woon Shin. Identification of plant compounds that disrupt the insect juvenile hormone receptor complex. Proceedings of the National Academy of Sciences of the United States of America. 2015 Feb; 112(6):1733-8. doi: 10.1073/pnas.1424386112. [PMID: 25624480]
  • Abraham Rami Horowitz, Isaac Ishaaya. Dynamics of biotypes B and Q of the whitefly Bemisia tabaci and its impact on insecticide resistance. Pest management science. 2014 Oct; 70(10):1568-72. doi: 10.1002/ps.3752. [PMID: 24488629]
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