Metrizoic acid (BioDeep_00000014878)

 

Secondary id: BioDeep_00000858541

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


3-(Acetylamino)-5-(acetylmethylamino)-2,4,6-triiodobenzoic acid

化学式: C12H11I3N2O4 (627.7853096)
中文名称: 甲泛影酸
谱图信息: 最多检出来源 Homo sapiens(blood) 13.33%

分子结构信息

SMILES: CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)N(C)C(=O)C)I
InChI: InChI=1S/C12H11I3N2O4/c1-4(18)16-10-7(13)6(12(20)21)8(14)11(9(10)15)17(3)5(2)19/h1-3H3,(H,16,18)(H,20,21)

描述信息

V - Various > V08 - Contrast media > V08A - X-ray contrast media, iodinated > V08AA - Watersoluble, nephrotropic, high osmolar x-ray contrast media
D006133 - Growth Substances > D010937 - Plant Growth Regulators > D014283 - Triiodobenzoic Acids
ATC code: V08AA02

同义名列表

15 个代谢物同义名

3-(Acetylamino)-5-(acetylmethylamino)-2,4,6-triiodobenzoic acid; 3-(Acetylamino)-5-(acetylmethylamino)-2,4,6-triiodobenzoate; 3-Acetamido-2,4,6-triiodo-5-(N-methylacetamido)benzoic acid; 3-Acetamido-2,4,6-triiodo-5-N-methylacetamidobenzoic acid; 3-Acetamido-2,4,6-triiodo-5-(N-methylacetamido)benzoate; 3-Acetamido-2,4,6-triiodo-5-N-methylacetamidobenzoate; Acidum metrizoicum; Sodium, metrizoate; Acide metrizoique; Metrizoate sodium; Metrizoic acid; Metrizoate; Isopaque; Triosil; Metrizoic acid



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Bun-Hee Lee, Yong-Ku Kim. BDNF mRNA expression of peripheral blood mononuclear cells was decreased in depressive patients who had or had not recently attempted suicide. Journal of affective disorders. 2010 Sep; 125(1-3):369-73. doi: 10.1016/j.jad.2010.01.074. [PMID: 20207421]
  • Manthena V S Varma, Bo Feng, R Scott Obach, Matthew D Troutman, Jonathan Chupka, Howard R Miller, Ayman El-Kattan. Physicochemical determinants of human renal clearance. Journal of medicinal chemistry. 2009 Aug; 52(15):4844-52. doi: 10.1021/jm900403j. [PMID: 19445515]
  • R Scott Obach, Franco Lombardo, Nigel J Waters. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals. 2008 Jul; 36(7):1385-405. doi: 10.1124/dmd.108.020479. [PMID: 18426954]
  • A Ryningen, H Holmsen. Role of autocrine stimulation for the effects of cyclic AMP on protein and lipid phosphorylation in platelets activated by particles. FEBS letters. 1998 Oct; 436(3):335-8. doi: 10.1016/s0014-5793(98)01154-5. [PMID: 9801143]
  • D Ferrero, C Tarella, C Cherasco, P Bondesan, P Omedè, R Ravaglia, D Caracciolo, C Castellino, A Pileri. A single step density gradient separation for large scale enrichment of mobilized peripheral blood progenitor cells collected for autotransplantation. Bone marrow transplantation. 1998 Feb; 21(4):409-13. doi: 10.1038/sj.bmt.1701094. [PMID: 9509977]
  • J M Idee, R Bourbouze. Effects of iodinated X-ray contrast media on renal epithelial cells in culture. Investigative radiology. 1995 May; 30(5):323-4. doi: NULL. [PMID: 7558738]
  • K J Andersen, E I Christensen, H Vik. Effects of iodinated x-ray contrast media on renal epithelial cells in culture. Investigative radiology. 1994 Nov; 29(11):955-62. doi: 10.1097/00004424-199411000-00002. [PMID: 7890510]
  • K Golman, B H Grynne. Nonionic dimer x-ray contrast media. Will they be of clinical benefit?. Investigative radiology. 1994 Jun; 29 Suppl 2(?):S230-1. doi: 10.1097/00004424-199406001-00077. [PMID: 7928240]
  • T Nybonde, H Wahlgren, O Brekke, D T Kristofferssen, W Mortensson. Image quality and safety in pediatric urography using an ionic and a non-ionic iodinated contrast agent. Pediatric radiology. 1994; 24(2):107-10. doi: 10.1007/bf02020165. [PMID: 8078710]
  • K J Andersen, H Vik. Use of renal epithelial cell lines for testing cellular toxicity. Contributions to nephrology. 1993; 101(?):227-34. doi: 10.1159/000422136. [PMID: 8467679]
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  • G Clemenzia, M Marvelli, G Sagliaschi, S Persichetti, M Re, G Gallo, C Spinelli, A Angelitti, G Punzo, S Maggi. [The evaluation of urinary NAG activity in patients undergoing urography]. Minerva medica. 1991 Apr; 82(4):195-200. doi: NULL. [PMID: 2017315]
  • A Nordby, K E Tvedt, J Halgunset, O A Haugen. Intracellular penetration and accumulation of radiographic contrast media in the rat kidney. Scanning microscopy. 1990 Sep; 4(3):651-64; discussion 664. doi: NULL. [PMID: 2080429]
  • G Stake, E Monn, K Rootwelt, K Golman, T Monclair. Influence of urography on renal function in children. A double blind study with metrizoate and iohexol. Acta radiologica (Stockholm, Sweden : 1987). 1989 Nov; 30(6):643-6. doi: NULL. [PMID: 2698748]
  • A Billström, S O Hietala, F Lithner, J Merikanto, M Wirell, S Wirell. Nephrotoxicity of contrast media in patients with diabetes mellitus. A comparative urographic and angiographic study with iohexol and metrizoate. Acta radiologica (Stockholm, Sweden : 1987). 1989 Sep; 30(5):509-15. doi: NULL. [PMID: 2692666]
  • C Cederholm, T Almén, D Bergqvist, K Golman, R Takolander. Acute renal failure in rats. Interaction between contrast media and temporary renal arterial occlusion. Acta radiologica (Stockholm, Sweden : 1987). 1989 May; 30(3):321-6. doi: NULL. [PMID: 2736186]
  • L Pokorny, E Nagy, G Vadon. Experience with low osmolar contrast media a clinical and experimental study. Annales de radiologie. 1989; 32(1):40-2. doi: NULL. [PMID: 2742325]
  • P Morsing, A E Persson, U Boberg. A micropuncture assessment of the effects of contrast media of different osmolality. Investigative radiology. 1988 Oct; 23(10):767-71. doi: 10.1097/00004424-198810000-00012. [PMID: 3192398]
  • S E Bäck, E Krutzén, P Nilsson-Ehle. Contrast media and glomerular filtration: dose dependence of clearance for three agents. Journal of pharmaceutical sciences. 1988 Sep; 77(9):765-7. doi: 10.1002/jps.2600770909. [PMID: 3147328]
  • M Boijsen, L Jacobsson, U Tylén. Glomerular filtration rate estimated from a single plasma sample after contrast-enhanced radiological examinations. Clinical physiology (Oxford, England). 1988 Jun; 8(3):309-16. doi: 10.1111/j.1475-097x.1988.tb00273.x. [PMID: 3135978]
  • S E Bäck, E Krutzén, P Nilsson-Ehle. Contrast media as markers for glomerular filtration: a pharmacokinetic comparison of four agents. Scandinavian journal of clinical and laboratory investigation. 1988 May; 48(3):247-53. doi: 10.3109/00365518809167491. [PMID: 3375780]
  • A Billström, S O Hietala, S Wirell. Effects of metrizoate and iohexol on the liver at visceral angiography. Acta radiologica (Stockholm, Sweden : 1987). 1987 Nov; 28(6):707-10. doi: NULL. [PMID: 2962603]
  • M Boijsen, L Jacobsson, U Tylén. Renal function measured by x-ray fluorescence analysis. A comparison between contrast medium clearance and non-simultaneous 51Cr-EDTA clearance. Acta radiologica (Stockholm, Sweden : 1987). 1987 Sep; 28(5):581-5. doi: NULL. [PMID: 2960352]
  • S Sjöberg, S Hellsten, T Almén, K Golman, T Grönberg. Estimating kidney function during urography. Comparison of contrast medium clearance and simultaneous 51Cr-EDTA clearance. Acta radiologica (Stockholm, Sweden : 1987). 1987 Sep; 28(5):587-92. doi: NULL. [PMID: 2960353]
  • R Nilsson, L Ehrenberg, I Fedorcsak. Formation of potential antigens from radiographic contrast media. Acta radiologica (Stockholm, Sweden : 1987). 1987 Jul; 28(4):473-7. doi: NULL. [PMID: 2958066]
  • B J van Weelde, J T Bakkers. Abnormal nephrogram pattern as an adverse reaction to contrast material. Case report. European journal of radiology. 1987 Feb; 7(1):70-1. doi: NULL. [PMID: 3830198]
  • J Edgren, L Laasonen, P H Groop, L Groop. Iohexol and metrizoate in urography of insulin dependent patients. Acta radiologica: diagnosis. 1986 May; 27(3):265-7. doi: 10.1177/028418518602700302. [PMID: 3751672]
  • C Cederholm, T Almén, D Bergqvist, K Golman, R Takolander. Acute renal failure in rats. Interaction between a contrast medium and renal arterial occlusion. Acta radiologica: diagnosis. 1986 Mar; 27(2):241-7. doi: 10.1177/028418518602700220. [PMID: 3716872]
  • U Albrechtsson, B Hultberg, H Lárusdóttir, L Norgren. Nephrotoxicity of ionic and non-ionic contrast media in aorto-femoral angiography. Acta radiologica: diagnosis. 1985 Sep; 26(5):615-8. doi: 10.1177/028418518502600519. [PMID: 2933926]
  • P E Nilsson, P Aspelin, S Holtås. Demonstration of the renal venous system at routine nephroangiography. A comparison between metrizoate, metrizamide and ioxaglate. Acta radiologica: diagnosis. 1985 Sep; 26(5):619-26. doi: 10.1177/028418518502600520. [PMID: 4072754]
  • T Almén, S E Bergentz, C Törnquist, B Oystese. Selective nephroangiography in the dog causing renal platelet aggregation and irregular nephrographic phase. Acta radiologica: diagnosis. 1985 Sep; 26(5):627-34. doi: 10.1177/028418518502600521. [PMID: 4072755]
  • H J Smith, K Levorstad, K J Berg, K Rootwelt, K Sveen. High dose urography in patients with renal failure. A double blind investigation of iohexol and metrizoate. Acta radiologica: diagnosis. 1985 Mar; 26(2):213-20. doi: 10.1177/028418518502600216. [PMID: 3993426]
  • K Golman, T Almén. Contrast media-induced nephrotoxicity. Survey and present state. Investigative radiology. 1985 Jan; 20(1 Suppl):S92-7. doi: 10.1097/00004424-198501002-00021. [PMID: 3972531]
  • J A Onyango-Abuje. The separation of Taenia saginata oncospheres from fecal debris. The Journal of parasitology. 1984 Feb; 70(1):146-8. doi: 10.2307/3281940. [PMID: 6539820]
  • C Törnquist, S Holtås. Renal angiography with iohexol and metrizoate. Radiology. 1984 Feb; 150(2):331-4. doi: 10.1148/radiology.150.2.6691084. [PMID: 6691084]
  • T Grönberg, S Sjöberg, T Almén, K Golman, S Mattsson. Noninvasive estimation of kidney function by x-ray fluorescence analysis. Elimination rate and clearance of contrast media injected for urography in man. Investigative radiology. 1983 Sep; 18(5):445-52. doi: NULL. [PMID: 6642941]
  • A Skjennald, J Heldaas, A Høiseth. Comparison of iohexol and meglumine-Na-Ca metrizoate in visceral angiography. Acta radiologica. Supplementum. 1983; 366(?):158-63. doi: NULL. [PMID: 6382931]
  • K Levorstad, S Simonsen, J Jervell. Tolerability and usefulness of iohexol in cardioangiography. II. A double blind comparison with metrizoate. Acta radiologica. Supplementum. 1983; 366(?):101-10. doi: NULL. [PMID: 6382927]
  • B E Zachrisson, R Jagenburg. Comparison of iohexol with metrizoate in urography. A single blind parallel investigation. Acta radiologica. Supplementum. 1983; 366(?):30-7. doi: NULL. [PMID: 6147958]
  • K Levorstad, A Kolbenstvedt, E W Løyning. Iohexol compared with metrizoate in urography. Acta radiologica: diagnosis. 1983; 24(4):337-42. doi: 10.1177/028418518302400411. [PMID: 6637574]
  • P E Nilsson, S L Holtås, L T Tejler. Subjective responses and albuminuria induced by ioxaglate during renal angiography in man. Radiology. 1982 Aug; 144(3):509-12. doi: 10.1148/radiology.144.3.7100462. [PMID: 7100462]
  • S O Hietala, B Lindqvist, F Lithner, M Wirell. Fatal reaction following renal angiography and biopsy in diabetic patients with Azotemia. Acta medica Scandinavica. 1982; 212(3):179-81. doi: 10.1111/j.0954-6820.1982.tb03194.x. [PMID: 7148509]
  • R L Eisenberg, W O Bank, M W Hedgock. Renal failure after major angiography can be avoided with hydration. AJR. American journal of roentgenology. 1981 May; 136(5):859-61. doi: 10.2214/ajr.136.5.859. [PMID: 6784516]
  • M Kelly, K Golman. Metabolism of urographic contrast media. Investigative radiology. 1981 Mar; 16(2):159-64. doi: 10.1097/00004424-198103000-00015. [PMID: 7216706]
  • L I Jensen, K Golman, T Almén, G Fex. Effect of angiographic contrast media on the liver. I. Serum concentration of enzymes after coeliacography with balloon catheter in the pig. Acta radiologica. Supplementum. 1980; 362(?):57-63. doi: NULL. [PMID: 6168169]
  • A E Nilson, M Aurell, C G Bratt, S Nilsson. Diuretic urography in the assessment of obstruction of the pelvi-ureteric junction. Acta radiologica: diagnosis. 1980; 21(4):499-503. doi: 10.1177/028418518002100412. [PMID: 6779504]
  • J Kråkenes, S Elsayed, J Göthlin, M Farstad. Proteinuria after selective nephroangiography in man. Comparison of three contrast media. Acta radiologica: diagnosis. 1980; 21(3):401-6. doi: 10.1177/028418518002100310. [PMID: 7001855]
  • A Skjennald. Amipaque in coeliac angiography. Acta radiologica: diagnosis. 1979; 20(3):417-21. doi: 10.1177/028418517902000303. [PMID: 525385]
  • P Aspelin. Effect of ionic and non-ionic contrast media on red cell deformability in vitro. Acta radiologica: diagnosis. 1979; 20(1):1-12. doi: 10.1177/028418517902001a01. [PMID: 433635]
  • P Aspelin. Effect of ionic and non-ionic contrast media on whole blood viscosity, plasma viscosity and hematocrit in vitro. Acta radiologica: diagnosis. 1978; 19(6):977-89. doi: 10.1177/028418517801900613. [PMID: 735850]
  • L Tejler, T Almén, S Holtås. Proteinuria following nephroangiography. I. Clinical experiences. Acta radiologica: diagnosis. 1977 Nov; 18(6):634-40. doi: 10.1177/028418517701800604. [PMID: 605812]
  • P V Sergeev, N K Sviridov. [Effect of triiodinated x-ray contrast media on the kidneys (review of the literature)]. Farmakologiia i toksikologiia. 1977 May; 40(3):376-81. doi: NULL. [PMID: 902733]
  • J G Johansen, O G Clausen. Antibacterial effects of metrizoate and metrizamide on bacterial growth in vitro. Acta radiologica: diagnosis. 1977 Mar; 18(2):269-72. doi: 10.1177/028418517701800219. [PMID: 404846]
  • K Golman. Urography. Physiological considerations on the excretion of contrast media. Journal belge de radiologie. 1977; 60(3):229-38. doi: NULL. [PMID: 338573]
  • L Tejler, M Ekberg, T Almén, S Holtås. Proteinuria following renal arteriography. Report of two cases. Acta medica Scandinavica. 1977; 202(1-2):131-3. doi: 10.1111/j.0954-6820.1977.tb16798.x. [PMID: 899876]
  • M Osnes, A Skjennald, S Larsen. A comparison of a new non-ionic (metrizamide) and a dissociable (metrizoate) contrast medium in endoscopic retrograde pancreatography (ERP). Scandinavian journal of gastroenterology. 1977; 12(7):821-5. doi: 10.3109/00365527709181725. [PMID: 594652]
  • R T Damian. Separation of Nematospiroides dubius infective larvae and eggs from gross fecal contaminants. The Journal of parasitology. 1976 Feb; 62(1):168-9. doi: 10.2307/3279090. [PMID: 943497]
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  • C R Dunn, E G Lasser, S Sell, J Lang. Failure to induce hypersensitivity reactions to opaque contrast media analogs in guinea pigs. Investigative radiology. 1975 Jul; 10(4):317-22. doi: 10.1097/00004424-197507000-00006. [PMID: 1184321]
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  • I O Skalpe, A Evensen. Toxicity of metrizamide, meglumine iocarmate and sodium metrizoate in selective nephroangiography. An experimental investigation in rabbits. Acta radiologica. Supplementum. 1973; 335(?):175-85. doi: 10.1177/0284185173014s33520. [PMID: 4534551]
  • K Golman. Metrizamide in experimental urography. II Iodine concentration intravenous injection of an ionic and a non-ionic contrast medium in rats. Acta radiologica. Supplementum. 1973; 335(?):323-9. doi: NULL. [PMID: 4534571]
  • K Golman, T Almén. Metrizamide in experimental urography. I. Iodine concentration and flow of urine following intravenous injection of an ionic and non-ionic contrast medium in rabbits. Acta radiologica. Supplementum. 1973; 335(?):312-22. doi: NULL. [PMID: 4534570]