Choline sulfate (BioDeep_00000014854)
Secondary id: BioDeep_00001869209
human metabolite blood metabolite
代谢物信息卡片
2-Hydroxy-N,N,N-trimethylethanaminium
化学式: C5H13NO4S (183.0565258)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 0.04%
分子结构信息
SMILES: C[N+](C)(C)CCOS(=O)(=O)[O-]
InChI: InChI=1S/C5H13NO4S/c1-6(2,3)4-5-10-11(7,8)9/h4-5H2,1-3H3
描述信息
D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D008082 - Lipotropic Agents
D002491 - Central Nervous System Agents > D018697 - Nootropic Agents
D009676 - Noxae > D000963 - Antimetabolites
D005765 - Gastrointestinal Agents
同义名列表
25 个代谢物同义名
2-Hydroxy-N,N,N-trimethylethanaminium; 2-(trimethylazaniumyl)ethyl sulfate; Choline sulphuric acid betaine; Choline sulfuric acid betaine; Choline sulphate betaine; Choline sulfate betaine; Choline sulphuric acid; Choline sulfuric acid; Bitartrate, choline; Choline bitartrate; O-Sulfate, choline; Hydroxide, choline; Choline O-sulfate; Choline Hydroxide; Chloride, choline; Choline O sulfate; Choline sulphate; Choline chloride; Citrate, choline; Choline sulfate; choline citrate; Choline; Bursine; Vidine; Fagine
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:16822
- KEGG: C00919
- PubChem: 485
- HMDB: HMDB0250194
- Metlin: METLIN63302
- MeSH: Choline
- KNApSAcK: C00001530
- chemspider: 471
- CAS: 4858-96-2
- PubChem: 4173
- 3DMET: B00199
- NIKKAJI: J814.134G
- RefMet: Choline sulfate
分类词条
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
3 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(3)
- choline-O-sulfate degradation:
A + choline ⟶ A(H2) + betaine aldehyde - choline-O-sulfate degradation:
H2O + NAD+ + betaine aldehyde ⟶ H+ + NADH + glycine betaine - choline-O-sulfate degradation:
A + choline ⟶ A(H2) + betaine aldehyde
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Anusha K S Dhanasiri, Daphne Siciliani, Trond M Kortner, Åshild Krogdahl. Epigenetic changes in pyloric caeca of Atlantic salmon fed diets containing increasing levels of lipids and choline.
Epigenetics.
2024 Dec; 19(1):2305079. doi:
10.1080/15592294.2024.2305079. [PMID: 38281164] - Yuan He, Ying Zhu, Xiaorong Shui, Zufeng Huang, Kongwei Li, Wei Lei. Gut microbiome and metabolomic profiles reveal the antiatherosclerotic effect of indole-3-carbinol in high-choline-fed ApoE-/- mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jul; 129(?):155621. doi:
10.1016/j.phymed.2024.155621. [PMID: 38678950] - Long Yu, Blagojce Jovcevski, Tara L Pukala, Vincent Bulone. Profiling and optimized extraction of bioactive polyphenolic compounds from young, red-fleshed apple using eco-friendly deep eutectic solvents.
Food research international (Ottawa, Ont.).
2024 Jul; 187(?):114334. doi:
10.1016/j.foodres.2024.114334. [PMID: 38763634] - Chenyu Jiang, Song Wang, Yihan Wang, Ketao Wang, Chunying Huang, Fei Gao, Huang Peng Hu, Yangyong Deng, Wen Zhang, Jian Zheng, Jianqin Huang, Yan Li. Polyphenols from hickory nut reduce the occurrence of atherosclerosis in mice by improving intestinal microbiota and inhibiting trimethylamine N-oxide production.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jun; 128(?):155349. doi:
10.1016/j.phymed.2024.155349. [PMID: 38522315] - Joanna Mikołajczyk-Stecyna, Ewelina Zuk, Agata Chmurzynska, Malgorzata Blatkiewicz, Karol Jopek, Marcin Rucinski. The effects of exposure to and timing of a choline-deficient diet during pregnancy and early postnatal life on the skeletal muscle transcriptome of the offspring.
Clinical nutrition (Edinburgh, Scotland).
2024 Jun; 43(6):1503-1515. doi:
10.1016/j.clnu.2024.05.002. [PMID: 38729079] - Natalia G Vallianou, Dimitris Kounatidis, Sotiria Psallida, Fotis Panagopoulos, Theodora Stratigou, Eleni Geladari, Irene Karampela, Dimitrios Tsilingiris, Maria Dalamaga. The Interplay Between Dietary Choline and Cardiometabolic Disorders: A Review of Current Evidence.
Current nutrition reports.
2024 06; 13(2):152-165. doi:
10.1007/s13668-024-00521-3. [PMID: 38427291] - Tetsuki Suzawa, Ryo Iwama, Ryouichi Fukuda, Hiroyuki Horiuchi. Phosphatidylcholine levels regulate hyphal elongation and differentiation in the filamentous fungus Aspergillus oryzae.
Scientific reports.
2024 05; 14(1):11729. doi:
10.1038/s41598-024-62580-4. [PMID: 38778216] - Ryohei Tanaka-Kanegae, Hiroyuki Kimura, Koichiro Hamada. Pharmacokinetics of soy-derived lysophosphatidylcholine compared with that of glycerophosphocholine: a randomized controlled trial.
Bioscience, biotechnology, and biochemistry.
2024 May; 88(6):648-655. doi:
10.1093/bbb/zbae031. [PMID: 38490741] - Li-Chan Yang, Chih-Chiang Wang, Der-Yen Lee, Wen-Chuan Lin, Sheng-Chu Kuo, Shin-Hun Juang, Min-Tsang Hsieh. 4,4-Diallyl curcumin bis(2,2-hydroxymethyl)propanoate ameliorates nonalcoholic steatohepatitis in methionine-choline-deficient diet and Western diet mouse models.
Chemical biology & drug design.
2024 May; 103(5):e14532. doi:
10.1111/cbdd.14532. [PMID: 38725089] - Jie Fang, Bo Zhang, Yulong Fan, Minjia Liu, Qing Xu, Yaji Huang, Huiyan Zhang. Optimizing invasive plant biomass valorization: Deep eutectic solvents pre-treatment coupled with ZSM-5 catalyzed fast pyrolysis for superior bio-oil quality.
Bioresource technology.
2024 May; 400(?):130652. doi:
10.1016/j.biortech.2024.130652. [PMID: 38575096] - Yeeun Son, Timothy C Kenny, Artem Khan, Kıvanç Birsoy, Richard K Hite. Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1.
Nature.
2024 May; 629(8012):710-716. doi:
10.1038/s41586-024-07374-4. [PMID: 38693265] - Maria-Christina Zerva, Christos Triantafylloudis, Vassilis Paspaliaris, Efthimios M C Skoulakis, Katerina Papanikolopoulou. Choline Metabolites Reverse Differentially the Habituation Deficit and Elevated Memory of Tau Null Drosophila.
Cells.
2024 Apr; 13(9):. doi:
10.3390/cells13090746. [PMID: 38727282] - Isma'il Kadam, Steven E Trasino, Hunter Korsmo, Jessica Lucas, Myriam Pinkas, Xinyin Jiang. Prenatal Choline Supplementation Improves Glucose Tolerance and Reduces Liver Fat Accumulation in Mouse Offspring Exposed to Ethanol during the Prenatal and Postnatal Periods.
Nutrients.
2024 Apr; 16(9):. doi:
10.3390/nu16091264. [PMID: 38732511] - Xuan Wang, Yuting Wei, Zhenyan Fan, Yueyuan Chen, Zhifang Cui. Life cycle assessment for evaluation of novel solvents and technologies: A case study of flavonoids extraction from Ginkgo biloba leaves.
The Science of the total environment.
2024 Apr; 922(?):171319. doi:
10.1016/j.scitotenv.2024.171319. [PMID: 38423327] - Chaofeng Wu, Junjie Li, Hui Jia, Jiamin Zhao, Mengchen Qin, Hao Shi, Chang Liu, Jiajie Lin, Min Cai, Yong Gu, Bin Liu, Lei Gao. Indoleamine 2,3-dioxygenase 1-mediated iron metabolism in macrophages contributes to lipid deposition in nonalcoholic steatohepatitis.
Journal of gastroenterology.
2024 04; 59(4):342-356. doi:
10.1007/s00535-024-02082-2. [PMID: 38402297] - Yi-Fei Nie, Jia-Ming Shang, Duan-Qin Liu, Wen-Qing Meng, Hui-Ping Ren, Chuan-Hua Li, Zhi-Feng Wang, Jing Lan. Apical papilla stem cell-derived exosomes regulate lipid metabolism and alleviate inflammation in the MCD-induced mouse NASH model.
Biochemical pharmacology.
2024 Apr; 222(?):116073. doi:
10.1016/j.bcp.2024.116073. [PMID: 38395263] - Simeng Chu, Fukui Shen, Wenjuan Liu, Jin Zhang, Xiaoying Wang, Min Jiang, Gang Bai. Sinapine targeting PLCβ3 EF hands disrupts Gαq-PLCβ3 interaction and ameliorates cardiovascular diseases.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Apr; 126(?):155200. doi:
10.1016/j.phymed.2023.155200. [PMID: 38387273] - Junmin Wang, Jiacheng Li, Yugang Fu, Yingying Zhu, Liubing Lin, Yong Li. Research progress, challenges and perspectives of phospholipids metabolism in the LXR‑LPCAT3 signaling pathway and its relation to NAFLD (Review).
International journal of molecular medicine.
2024 Apr; 53(4):. doi:
10.3892/ijmm.2024.5356. [PMID: 38362962] - Shihui Mei, Guangxia He, Tiantian Zhang, Ze Chen, Rong Zhang, Yixiao Liao, Mingming Zhu, Duhan Xu, Yanjuan Shen, Bijun Zhou, Kaigong Wang, Chunmei Wang, Chao Chen, Erpeng Zhu, Zhentao Cheng. Effect of feeding fermented distiller's grains diets on immune status and metabolomics of spleen and mesenteric lymph nodes in finishing cattle.
Journal of proteomics.
2024 03; 296(?):105107. doi:
10.1016/j.jprot.2024.105107. [PMID: 38325729] - Caleigh M Sawicki, Lorena S Pacheco, Sona Rivas-Tumanyan, Zheyi Cao, Danielle E Haslam, Liming Liang, Katherine L Tucker, Kaumudi Joshipura, Shilpa N Bhupathiraju. Association of Gut Microbiota-Related Metabolites and Type 2 Diabetes in Two Puerto Rican Cohorts.
Nutrients.
2024 Mar; 16(7):. doi:
10.3390/nu16070959. [PMID: 38612993] - Jie Yang, Manyun Dai, Ying Wang, Zheng Yan, Shuqi Mao, Aiming Liu, Caide Lu. A CDAHFD-induced mouse model mimicking human NASH in the metabolism of hepatic phosphatidylcholines and acyl carnitines.
Food & function.
2024 Mar; 15(6):2982-2995. doi:
10.1039/d3fo05111k. [PMID: 38411344] - Mengqi Zhang, Xiaofeng Shi, Minglei Tang, Wen Yin, Cheng Luo, Xiangyang Xie. PRDX2 deficiency increases MCD-induced nonalcoholic steatohepatitis in female mice.
Biochemical and biophysical research communications.
2024 Mar; 701(?):149589. doi:
10.1016/j.bbrc.2024.149589. [PMID: 38309152] - Mei-Ting Tai, Chen-Fang Zhang, Chao-Wen Fan, Wei-Yi Tian, Qi Yu, Yan Fu, De-Li Xia, Meng-Lan Mao, Dan-Lu Shi, Zun-Li Ke. [Intervention effect of Erchen Decoction on methionine and choline deficient diet-induced non-alcoholic steatohepatitis in mice].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2024 Mar; 49(5):1310-1317. doi:
10.19540/j.cnki.cjcmm.20231013.401. [PMID: 38621978] - Daniel Leclerc, Karen E Christensen, Alaina M Reagan, Vafa Keser, Yan Luan, Olga V Malysheva, Brandi Wasek, Teodoro Bottiglieri, Marie A Caudill, Gareth R Howell, Rima Rozen. Folate Deficiency and/or the Genetic Variant Mthfr677C >T Can Drive Hepatic Fibrosis or Steatosis in Mice, in a Sex-Specific Manner.
Molecular nutrition & food research.
2024 Mar; 68(5):e2300355. doi:
10.1002/mnfr.202300355. [PMID: 38327171] - Xiao-Yue Li, Zhu-Lin Yu, Ying-Cai Zhao, Dan-Dan Wang, Chang-Hu Xue, Tian-Tian Zhang, Yu-Ming Wang. Gut Microbiota Metabolite TMA May Mediate the Effects of TMAO on Glucose and Lipid Metabolism in C57BL/6J Mice.
Molecular nutrition & food research.
2024 Mar; 68(6):e2300443. doi:
10.1002/mnfr.202300443. [PMID: 38456781] - Mara Caputo, Emma Andersson, Ying Xia, Wei Hou, Emmelie Cansby, Max Erikson, Dan Emil Lind, Bengt Hallberg, Manoj Amrutkar, Margit Mahlapuu. Genetic Ablation of STE20-Type Kinase MST4 Does Not Alleviate Diet-Induced MASLD Susceptibility in Mice.
International journal of molecular sciences.
2024 Feb; 25(4):. doi:
10.3390/ijms25042446. [PMID: 38397122] - Hexiang Liu, Jialong Lv, Yajun Yang. Recyclable water-modified deep eutectic solvents for removal of multiple heavy metals from soil.
Chemosphere.
2024 Feb; 350(?):141141. doi:
10.1016/j.chemosphere.2024.141141. [PMID: 38185420] - Fan Zhang, Lingnan Guo, Jingjing Shi, Hao Jiang, Feini Zhou, Yanlin Zhou, Bin Lv, Maosheng Xu. Choline metabolism in regulating inflammatory bowel disease-linked anxiety disorders: A multi-omics exploration of the gut-brain axis.
Neurobiology of disease.
2024 Feb; 191(?):106390. doi:
10.1016/j.nbd.2023.106390. [PMID: 38145852] - Fabian Alperth, Theresa Feistritzer, Melanie Huber, Olaf Kunert, Franz Bucar. Natural Deep Eutectic Solvents for the Extraction of Spilanthol from Acmella oleracea (L.) R.K.Jansen.
Molecules (Basel, Switzerland).
2024 Jan; 29(3):. doi:
10.3390/molecules29030612. [PMID: 38338357] - Rima Obeid, Christiane Schön, Emma Derbyshire, Xinyin Jiang, Tiffany J Mellott, Jan Krzysztof Blusztajn, Steven H Zeisel. A Narrative Review on Maternal Choline Intake and Liver Function of the Fetus and the Infant; Implications for Research, Policy, and Practice.
Nutrients.
2024 Jan; 16(2):. doi:
10.3390/nu16020260. [PMID: 38257153] - Ah Young Yang, Kiryeong Kim, Hyun Hee Kwon, Jaechan Leem, Jeong Eun Song. 6-Shogaol Ameliorates Liver Inflammation and Fibrosis in Mice on a Methionine- and Choline-Deficient Diet by Inhibiting Oxidative Stress, Cell Death, and Endoplasmic Reticulum Stress.
Molecules (Basel, Switzerland).
2024 Jan; 29(2):. doi:
10.3390/molecules29020419. [PMID: 38257332] - Li Yang, Yuchen Kang, Na Li, Yuhao Wang, Haiyan Mou, Hui Sun, Tianqi Ao, Li Chen, Wenqing Chen. Unlocking hormesis and toxic effects induced by cadmium in Polygonatum cyrtonema Hua based on morphology, physiology and metabolomics.
Journal of hazardous materials.
2024 Jan; 465(?):133447. doi:
10.1016/j.jhazmat.2024.133447. [PMID: 38219579] - Surpreet Kaur, Sucheta Sharma, Prabhjot Singla. Selenium treatment alters the accumulation of osmolytes in arsenic-stressed rice (Oryza sativa L.).
Environmental science and pollution research international.
2024 Jan; ?(?):. doi:
10.1007/s11356-024-31890-5. [PMID: 38198089] - Xiuduan Xu, Jianqin Wang, Li Xu, Peng Li, Peng Jiang. p53 suppresses lipid droplet-fueled tumorigenesis through phosphatidylcholine.
The Journal of clinical investigation.
2024 Jan; ?(?):. doi:
10.1172/jci171788. [PMID: 38194288] - Chiat Han Chang, Wei Cun See Too, Boon Huat Lim, Ling Ling Few. Identification and Characterization of Entamoeba histolytica Choline Kinase.
Acta parasitologica.
2024 Jan; ?(?):. doi:
10.1007/s11686-023-00763-1. [PMID: 38172465] - Chutikun Kanjanaruch, Kerri A Bochantin, Bethania J Dávila Ruiz, Jessica Syring, Yssi Entzie, Layla King, Pawel P Borowicz, Matthew S Crouse, Joel S Caton, Carl R Dahlen, Alison K Ward, Lawrence P Reynolds. One-carbon metabolite supplementation to nutrient-restricted beef heifers affects placental vascularity during early pregnancy.
Journal of animal science.
2024 Jan; 102(?):. doi:
10.1093/jas/skae044. [PMID: 38407272] - Javad Radmard, Ali Mohamadi Sani, Akram Arianfar, Behrooz Mahmoodzadeh Vaziri. Efficient extraction of oleoresin from Ferula gummosa roots by natural deep eutectic solvent and its structure and chemical characterizations.
Scientific reports.
2024 01; 14(1):148. doi:
10.1038/s41598-023-46198-6. [PMID: 38167968] - Bhanu Pratap Singh, Sudheer K Cheppali, Ishita Saha, Musti J Swamy. Contrasting effects of molecular crowding on the membrane-perturbing and chaperone-like activities of major bovine seminal plasma protein, PDC-109.
International journal of biological macromolecules.
2024 Jan; 254(Pt 2):127573. doi:
10.1016/j.ijbiomac.2023.127573. [PMID: 37923045] - Raman Singh, Himanshi Gupta, Anmol, Gaurav Aggarwal, Kangkanjyoti Bhattacharyya, Upendra Sharma, S G Eswara Reddy. Cyperus rotundus L.: Invasive weed plant with insecticidal potential against Aphis craccivora Koch and Planococcus lilacinus (Cockerell).
Pesticide biochemistry and physiology.
2024 Jan; 198(?):105720. doi:
10.1016/j.pestbp.2023.105720. [PMID: 38225075] - Xiangyu Liu, Bo Zhang, Junsheng Tian, Yumei Han. Plasma metabolomics reveals the intervention mechanism of different types of exercise on chronic unpredictable mild stress-induced depression rat model.
Metabolic brain disease.
2024 Jan; 39(1):1-13. doi:
10.1007/s11011-023-01310-7. [PMID: 37999885] - Huiqing Zhu, Yuanyuan Wu, Ziming Zhuang, Jing Xu, Feilong Chen, Qirui Wang, Qingfa Tang. Ampelopsis japonica aqueous extract improves ovulatory dysfunction in PCOS by modulating lipid metabolism.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2024 Jan; 170(?):116093. doi:
10.1016/j.biopha.2023.116093. [PMID: 38159378] - Dong-Keon Lee, Su Ho Jo, Eun Soo Lee, Kyung Bong Ha, Na Won Park, Deok-Hoon Kong, Sang-In Park, Joon Seok Park, Choon Hee Chung. DWN12088, A Prolyl-tRNA Synthetase Inhibitor, Alleviates Hepatic Injury in Nonalcoholic Steatohepatitis.
Diabetes & metabolism journal.
2024 Jan; 48(1):97-111. doi:
10.4093/dmj.2022.0367. [PMID: 38173372] - Ildefonso Rodriguez-Ramiro, Andrés Pastor-Fernández, José Luis López-Aceituno, Esther Garcia-Dominguez, Aranzazu Sierra-Ramirez, Angela M Valverde, Bárbara Martinez-Pastor, Alejo Efeyan, Mari Carmen Gomez-Cabrera, José Viña, Pablo J Fernandez-Marcos. Pharmacological and genetic increases in liver NADPH levels ameliorate NASH progression in female mice.
Free radical biology & medicine.
2024 Jan; 210(?):448-461. doi:
10.1016/j.freeradbiomed.2023.11.019. [PMID: 38036067] - Y Wang, M J O Wakelam, V A Bankaitis, M I McDermott. The wide world of non-mammalian phospholipase D enzymes.
Advances in biological regulation.
2024 Jan; 91(?):101000. doi:
10.1016/j.jbior.2023.101000. [PMID: 38081756] - Tomoyuki Sato, Katsutaka Oishi. Time-restricted feeding has a limited effect on hepatic lipid accumulation, inflammation and fibrosis in a choline-deficient high-fat diet-induced murine NASH model.
PloS one.
2024; 19(1):e0296950. doi:
10.1371/journal.pone.0296950. [PMID: 38285666] - Dmitriy A Karpitskiy, Elena A Bessonova, Andrey Yu Shishov, Liudmila A Kartsova. Selective extraction of plant bioactive compounds with deep eutectic solvents: Iris sibirica L. as example.
Phytochemical analysis : PCA.
2024 Jan; 35(1):53-63. doi:
10.1002/pca.3272. [PMID: 37545032] - Lauren E Louck, Kelly C Cara, Kevin Klatt, Taylor C Wallace, Mei Chung. The Relationship of Circulating Choline and Choline-Related Metabolite Levels with Health Outcomes: A Scoping Review of Genome-Wide Association Studies and Mendelian Randomization Studies.
Advances in nutrition (Bethesda, Md.).
2023 Dec; 15(2):100164. doi:
10.1016/j.advnut.2023.100164. [PMID: 38128611] - T C Marques, H F Monteiro, D B Melo, W M Coelho, S Salman, L R Marques, K M Leão, V S Machado, P Menta, F S Lima, D Dubey, F Sun. Effect of rumen-protected choline on dairy cows' metabolism, immunity, lactation performance, and vaginal discharge microbiome.
Journal of dairy science.
2023 Dec; ?(?):. doi:
10.3168/jds.2023-23850. [PMID: 38101729] - Václav Šmíd, Karel Dvořák, Kamila Stehnová, Hynek Strnad, Josep Rubert, Jan Stříteský, Barbora Staňková, Milena Stránská, Jana Hajšlová, Radan Brůha, Libor Vítek. The Ameliorating Effects of n-3 Polyunsaturated Fatty Acids on Liver Steatosis Induced by a High-Fat Methionine Choline-Deficient Diet in Mice.
International journal of molecular sciences.
2023 Dec; 24(24):. doi:
10.3390/ijms242417226. [PMID: 38139055] - Hang Chu, Weitao Zhang, Yan Tan, Zhipeng Diao, Peng Li, Yapeng Wu, Like Xie, Jianguo Sun, Ke Yang, Pingping Li, Cen Xie, Ping Li, Qian Hua, Xiaojun Xu. Qing-Zhi-Tiao-Gan-Tang (QZTGT) prevents nonalcoholic steatohepatitis (NASH) by expression pattern correction.
Journal of ethnopharmacology.
2023 Dec; 317(?):116665. doi:
10.1016/j.jep.2023.116665. [PMID: 37279813] - Limeng Sun, Hu Yan, Ye Zhang. Magnetic resonance spectroscopy (MRS) of multifidus muscle metabolites in chronic low back pain (CLBP).
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society.
2023 12; 32(12):4397-4404. doi:
10.1007/s00586-023-07933-9. [PMID: 37721604] - Firoozeh Hosseini-Esfahani, Glareh Koochakpoor, Mahdieh Golzarand, Parvin Mirmiran, Fereidoun Azizi. Dietary Intakes of Choline and Betaine and Incidence of Type 2 Diabetes: Tehran Lipid and Glucose Study.
Metabolic syndrome and related disorders.
2023 Dec; 21(10):573-580. doi:
10.1089/met.2023.0096. [PMID: 37816243] - Gulay Ozkan. Valorization of artichoke outer petals by using ultrasound-assisted extraction and natural deep eutectic solvents (NADES) for the recovery of phenolic compounds.
Journal of the science of food and agriculture.
2023 Nov; ?(?):. doi:
10.1002/jsfa.13158. [PMID: 37989526] - Pengfei Jiao, Xingmei He, Shihua Ma, Shengping Wang, Qiuhong Niu. Ultrasonic-Assisted Extraction of Antioxidants from Perilla frutescens Leaves Based on Tailor-Made Deep Eutectic Solvents: Optimization and Antioxidant Activity.
Molecules (Basel, Switzerland).
2023 Nov; 28(22):. doi:
10.3390/molecules28227554. [PMID: 38005276] - Xia Jiang, Zhaotun Hu, Xiaoyan Qiu, Liming Wu, Rong Zhou, Yaoyao Yang, Xiaoliang Xiang. Poria cocos (Schw.) Wolf, a Traditional Chinese Edible Medicinal Herb, Promotes Neuronal Differentiation, and the Morphological Maturation of Newborn Neurons in Neural Stem/Progenitor Cells.
Molecules (Basel, Switzerland).
2023 Nov; 28(22):. doi:
10.3390/molecules28227480. [PMID: 38005201] - Dong Yun Kim, Jun Yong Park, Heon Yung Gee. Lactobacillus plantarum ameliorates NASH-related inflammation by upregulating L-arginine production.
Experimental & molecular medicine.
2023 Nov; ?(?):. doi:
10.1038/s12276-023-01102-0. [PMID: 37907736] - Zhi Ying Lai, Chung Loong Yiin, Serene Sow Mun Lock, Bridgid Lai Fui Chin, Nur Syuhada Ahmad Zauzi, Sherena Sar-Ee. A review on natural based deep eutectic solvents (NADESs): fundamentals and potential applications in removing heavy metals from soil.
Environmental science and pollution research international.
2023 Nov; 30(55):116878-116905. doi:
10.1007/s11356-023-26288-8. [PMID: 36917382] - Even Fjære, Lene Secher Myrmel, Josef D Rasinger, Annette Bernhard, Livar Frøyland, Lise Madsen. Refined mackerel oil increases hepatic lipid accumulation and reduces choline and choline-containing metabolites in the liver tissue in mice fed a Western diet.
Food research international (Ottawa, Ont.).
2023 Nov; 173(Pt 2):113450. doi:
10.1016/j.foodres.2023.113450. [PMID: 37803779] - Chenchen Liang, Siyuan Gao, Jianpeng Gao, Yanwen Xu, Qilong Li. Comparison of effects of HucMSCs, exosomes, and conditioned medium on NASH.
Scientific reports.
2023 10; 13(1):18431. doi:
10.1038/s41598-023-45828-3. [PMID: 37891247] - Hua-Jun Li, Yuan-Song Wang, Ya-Nan Wang, Ai-Ru Liu, Xiu-Hai Su, Zi-Ang Ma, Li-Xin Wang, Zhong-Yong Zhang, Shu-Quan Lv, Jing Miao, Huan-Tian Cui. Mechanical study of alisol B 23-acetate on methionine and choline deficient diet-induced nonalcoholic steatohepatitis based on untargeted metabolomics.
Biomedical chromatography : BMC.
2023 Oct; ?(?):e5763. doi:
10.1002/bmc.5763. [PMID: 37858975] - Nicola A Gillies, Amber M Milan, David Cameron-Smith, Karen D Mumme, Cathryn A Conlon, Pamela R von Hurst, Crystal F Haskell-Ramsay, Beatrix Jones, Nicole C Roy, Jane Coad, Clare R Wall, Kathryn L Beck. Vitamin B and One-Carbon Metabolite Profiles Show Divergent Associations with Cardiometabolic Risk Markers but not Cognitive Function in Older New Zealand Adults: A Secondary Analysis of the REACH Study.
The Journal of nutrition.
2023 Oct; ?(?):. doi:
10.1016/j.tjnut.2023.10.012. [PMID: 37863266] - Ying Quan, Diwen Shou, Siqi Yang, Jiemin Cheng, Yongqiang Li, Chen Huang, Huiting Chen, Yongjian Zhou. Mdivi1 ameliorates mitochondrial dysfunction in non-alcoholic steatohepatitis by inhibiting JNK/MFF signaling.
Journal of gastroenterology and hepatology.
2023 Oct; ?(?):. doi:
10.1111/jgh.16372. [PMID: 37839851] - Yoon-Kwang Lee, Jung Eun Park, Mikang Lee, Ryan Mifflin, Yang Xu, Robert Novak, Yanqiao Zhang, James P Hardwick. Deletion of hepatic Small Heterodimer Partner ameliorates development of nonalcoholic steatohepatitis in mice.
Journal of lipid research.
2023 Oct; ?(?):100454. doi:
10.1016/j.jlr.2023.100454. [PMID: 37827334] - Shan Huang, Si Ying Lim, Sock Hwee Tan, Mark Y Chan, Wuzhong Ni, Sam Fong Yau Li. Targeted Plasma Metabolomics Reveals Association of Acute Myocardial Infarction Risk with the Dynamic Balance between Trimethylamine-N-oxide, Betaine, and Choline.
Journal of agricultural and food chemistry.
2023 Oct; ?(?):. doi:
10.1021/acs.jafc.2c08241. [PMID: 37781984] - Yong-Jing Liu, Li Lou, Qun Huang, Wei Xu, Hua Li. Ultrasonic extraction and purification of scutellarin from Erigerontis Herba using deep eutectic solvent.
Ultrasonics sonochemistry.
2023 Oct; 99(?):106560. doi:
10.1016/j.ultsonch.2023.106560. [PMID: 37625256] - Xin Liu, Yi Fang, Chenchen Qian, Jiahao Chen, Wu Luo, Wei Zuo, Jianjun Lin, Longteng Xie, Guang Liang, Lijiang Huang, Yi Wang. CARD9 deficiency aggravated nonalcoholic steatohepatitis in mice through increasing inflammatory response.
Biochimica et biophysica acta. Molecular basis of disease.
2023 Sep; 1870(1):166893. doi:
10.1016/j.bbadis.2023.166893. [PMID: 37751783] - Jiage Dai, Jiabao Cai, Taipeng Zhang, Mingyue Pang, Xiaoling Xu, Jiahua Bai, Yan Liu, Yusheng Qin. Transcriptome and Metabolome Analyses Reveal the Mechanism of Corpus Luteum Cyst Formation in Pigs.
Genes.
2023 09; 14(10):. doi:
10.3390/genes14101848. [PMID: 37895197] - Youngmi Song, Hyekyung Yang, Juhee Kim, Yoonjin Lee, Sung-Ho Kim, In-Gu Do, Cheol-Young Park. Gemigliptin, a DPP4 inhibitor, ameliorates nonalcoholic steatohepatitis through AMP-activated protein kinase-independent and ULK1-mediated autophagy.
Molecular metabolism.
2023 Sep; 78(?):101806. doi:
10.1016/j.molmet.2023.101806. [PMID: 37739179] - Vittoria Borgonetti, Nicoletta Galeotti. Novel Combination of Choline with Withania somnifera (L.) Dunal, and Bacopa monnieri (L.) Wetts Reduced Oxidative Stress in Microglia Cells, Promoting Neuroprotection.
International journal of molecular sciences.
2023 Sep; 24(18):. doi:
10.3390/ijms241814038. [PMID: 37762339] - Wenyan Lu, Jingna Yang, Mingyue Hu, Kai Zhong, Yueying Wang, Yanbin Yang, Juan J Loor, Guoyu Yang, Liqiang Han. Effects of choline deficiency and supplementation on lipid droplet accumulation in bovine primary liver cells in vitro.
Journal of dairy science.
2023 Sep; ?(?):. doi:
10.3168/jds.2023-23452. [PMID: 37678795] - Alejandra Bermúdez-Oria, Africa Fernández-Prior, María Luisa Castejón, Guillermo Rodríguez-Gutiérrez, Juan Fernández-Bolaños. Extraction of polyphenols associated with pectin from olive waste (alperujo) with choline chloride.
Food chemistry.
2023 Sep; 419(?):136073. doi:
10.1016/j.foodchem.2023.136073. [PMID: 37030208] - Peyman Ghorbani, Sang Yong Kim, Tyler K T Smith, Lucía Minarrieta, Victoria Robert-Gostlin, Marisa K Kilgour, Maja Ilijevska, Irina Alecu, Shayne A Snider, Kaitlyn D Margison, Julia R C Nunes, Daniel Woo, Ciara Pember, Conor O'Dwyer, Julie Ouellette, Pavel Kotchetkov, Julie St-Pierre, Steffany A L Bennett, Baptiste Lacoste, Alexandre Blais, Meera G Nair, Morgan D Fullerton. Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection.
PLoS pathogens.
2023 Sep; 19(9):e1011658. doi:
10.1371/journal.ppat.1011658. [PMID: 37747879] - Wenzhi Zhao, Yanfeng Sun, Xiaoyong Wei, Guangyuan Niu, Chuanfang Zhou. Determination of major and trace elements in plant samples by inductively coupled plasma optical emission spectrometry with deep eutectic solvent extraction based on choline chloride and carboxylic acids.
Analytical methods : advancing methods and applications.
2023 08; 15(34):4275-4281. doi:
10.1039/d3ay00958k. [PMID: 37592886] - Yu-Feng Song, Zhen-Yu Bai, Zhi Luo, Ling-Jiao Wang, Hua Zheng. Choline mediated hepatic lipid homeostasis in yellow catfish: Unravelling choline's lipotropic and methyl donor functions and significance of ire-1α signalling pathway.
The British journal of nutrition.
2023 Aug; ?(?):1-26. doi:
10.1017/s000711452300185x. [PMID: 37642130] - Catherine J Andersen, Lindsey Huang, Fangyi Zhai, Christa Palancia Esposito, Julia M Greco, Ruijie Zhang, Rachael Woodruff, Allison Sloan, Aaron R Van Dyke. Consumption of Different Egg-Based Diets Alters Clinical Metabolic and Hematological Parameters in Young, Healthy Men and Women.
Nutrients.
2023 Aug; 15(17):. doi:
10.3390/nu15173747. [PMID: 37686779] - D N Sherlock, E Abdel-Hamied, R Bucktrout, Y Liang, M Miura, J J Loor. Post-ruminal choline supply during negative nutrient balance alters components of hepatic mTOR signaling and plasma amino acids in lactating Holstein cows.
Journal of dairy science.
2023 Aug; ?(?):. doi:
10.3168/jds.2023-23239. [PMID: 37641280] - Alessandre C Crispim, Shirley M A Crispim, Jéssica R Rocha, Jeferson S Ursulino, Roberto R Sobrinho, Viviane A Porto, Edson S Bento, Antônio E G Santana, Luiz C Caetano. Light effects on Lasiodiplodia theobromae metabolome cultured in vitro.
Metabolomics : Official journal of the Metabolomic Society.
2023 08; 19(8):75. doi:
10.1007/s11306-023-02041-7. [PMID: 37580624] - Arne Doose, Friederike I Tam, Inger Hellerhoff, Joseph A King, Ilka Boehm, Kim Gottloeber, Hannes Wahl, Annett Werner, Felix Raschke, Brenda Bartnik-Olson, Alexander P Lin, Katja Akgün, Veit Roessner, Jennifer Linn, Stefan Ehrlich. Triangulating brain alterations in anorexia nervosa: a multimodal investigation of magnetic resonance spectroscopy, morphometry and blood-based biomarkers.
Translational psychiatry.
2023 Aug; 13(1):277. doi:
10.1038/s41398-023-02580-6. [PMID: 37573444] - Yi Hu, Peiyi Liang, Zhuxian Wang, CuiPing Jiang, Quanfu Zeng, Chunyan Shen, Yufan Wu, Li Liu, Yankui Yi, Hongxia Zhu, Qiang Liu. Exploring the mechanism of solubilization and release of isoliquiritigenin in deep eutectic solvents.
International journal of pharmaceutics.
2023 Aug; ?(?):123298. doi:
10.1016/j.ijpharm.2023.123298. [PMID: 37558146] - Qijun Sun, Xiaoyu Xu, Song Liu, Xinzhao Wu, Chenhui Yin, Meng Wu, Yuxue Chen, Na Niu, Ligang Chen, Fuquan Bai. Mo Single-Atom Nanozyme Anchored to the 2D N-Doped Carbon Film: Catalytic Mechanism, Visual Monitoring of Choline, and Evaluation of Intracellular ROS Generation.
ACS applied materials & interfaces.
2023 Aug; 15(30):36124-36134. doi:
10.1021/acsami.3c04761. [PMID: 37466481] - Regina Leibe, Susanne Fritsch-Decker, Florian Gussmann, Ane Marit Wagbo, Parvesh Wadhwani, Silvia Diabaté, Wolfgang Wenzel, Anne S Ulrich, Carsten Weiss. Key Role of Choline Head Groups in Large Unilamellar Phospholipid Vesicles for the Interaction with and Rupture by Silica Nanoparticles.
Small (Weinheim an der Bergstrasse, Germany).
2023 08; 19(34):e2207593. doi:
10.1002/smll.202207593. [PMID: 37098631] - Jawaher AlYammahi, Ahmad S Darwish, Ghaiath Almustafa, Tarek Lemaoui, Inas M AlNashef, Shadi W Hasan, Hanifa Taher, Fawzi Banat. Natural deep eutectic solvents for Ultrasonic-Assisted extraction of nutritious date Sugar: Molecular Screening, Experimental, and prediction.
Ultrasonics sonochemistry.
2023 Aug; 98(?):106514. doi:
10.1016/j.ultsonch.2023.106514. [PMID: 37421845] - Katarzyna Pastuszak, Bozena Kowalczyk, Jacek Tarasiuk, Rafal Luchowski, Wieslaw I Gruszecki, Małgorzata Jurak, Marta Palusinska-Szysz. Insight into the Mechanism of Interactions between the LL-37 Peptide and Model Membranes of Legionella gormanii Bacteria.
International journal of molecular sciences.
2023 Jul; 24(15):. doi:
10.3390/ijms241512039. [PMID: 37569419] - Saffron J Bryant, Aaron Elbourne, Tamar L Greaves, Gary Bryant. Phytantriol phase behaviour in choline chloride urea and water mixtures.
Journal of materials chemistry. B.
2023 07; 11(29):6868-6880. doi:
10.1039/d3tb00554b. [PMID: 37403522] - Ensiye Soleimani, Abnoos Mokhtari Ardekani, Ehsan Fayyazishishavan, Mahdieh Abbasalizad Farhangi. The interactive relationship of dietary choline and betaine with physical activity on circulating creatine kinase (CK), metabolic and glycemic markers, and anthropometric characteristics in physically active young individuals.
BMC endocrine disorders.
2023 Jul; 23(1):158. doi:
10.1186/s12902-023-01413-3. [PMID: 37491240] - Tong Wu, Qiu-Ye Lan, Fang Tian, Xiao-Ying Xiong, Meng-Tao Yang, Si-Yu Huang, Xiao-Yan Chen, Matthew J Kuchan, Xiang Li, Yan-Rong Zhao, Ying-Yi Mao, Hui-Lian Zhu. Longitudinal changes in choline concentration and associated factors in human breast milk.
Clinical nutrition (Edinburgh, Scotland).
2023 Jul; 42(9):1647-1656. doi:
10.1016/j.clnu.2023.07.016. [PMID: 37515842] - Kuai Ma, Xin Hu, Keiki Nambu, Daisuke Ueda, Naotsugu Ichimaru, Masayuki Fujino, Xiao-Kang Li. Coral calcium carried hydrogen ameliorates the severity of non-alcoholic steatohepatitis induced by a choline deficient high carbohydrate fat-free diet in elderly rats.
Scientific reports.
2023 07; 13(1):11646. doi:
10.1038/s41598-023-38856-6. [PMID: 37468618] - Hui Zhou, Bin Niu, Xue Wu, Weike Chu, Yibing Zhou, Ze Chen, Yuqiang Mi, Yonggang Liu, Ping Li. iTRAQ-based quantitative proteomics analysis of the effect of ACT001 on non-alcoholic steatohepatitis in mice.
Scientific reports.
2023 07; 13(1):11336. doi:
10.1038/s41598-023-38448-4. [PMID: 37443174] - Junjie Zhang, Tiantian Zhang, Duhan Xu, Mingming Zhu, Xiaofen Luo, Rong Zhang, Guangxia He, Ze Chen, Shihui Mei, Bijun Zhou, Kaigong Wang, Erpeng Zhu, Zhentao Cheng, Chao Chen. Plasma Metabolomic Profiling after Feeding Dried Distiller's Grains with Solubles in Different Cattle Breeds.
International journal of molecular sciences.
2023 Jun; 24(13):. doi:
10.3390/ijms241310677. [PMID: 37445854] - Esra Tuğçe Gül, Osman Olgun, Gözde Kılınç, Alpönder Yıldız, Ainhoa Sarmiento-García. Does the addition of choline and/or betaine to diets reduce the methionine requirements of laying quails? Assessment of performance and egg antioxidant capacity.
Poultry science.
2023 May; 102(8):102816. doi:
10.1016/j.psj.2023.102816. [PMID: 37302323] - H T Holdorf, S J Kendall, K E Ruh, M J Caputo, G J Combs, S J Henisz, W E Brown, T Bresolin, R E P Ferreira, J R R Dorea, H M White. Increasing the prepartum dose of rumen-protected choline: Effects on milk production and metabolism in high-producing Holstein dairy cows.
Journal of dairy science.
2023 May; ?(?):. doi:
10.3168/jds.2022-22905. [PMID: 37225582] - U Arshad, A Husnain, M B Poindexter, R Zimpel, M C Perdomo, J E P Santos. Effect of source and amount of rumen-protected choline on hepatic metabolism during induction of fatty liver in dairy cows.
Journal of dairy science.
2023 May; ?(?):. doi:
10.3168/jds.2023-23270. [PMID: 37210357] - S B Potts, K M Brady, C M Scholte, K M Moyes, N E Sunny, R A Erdman. Rumen-protected choline and methionine during the periparturient period affect choline metabolites, amino acids, and hepatic expression of genes associated with one-carbon and lipid metabolism.
Journal of dairy science.
2023 May; ?(?):. doi:
10.3168/jds.2022-22334. [PMID: 37173256] - Zhenhua Wang, Meng Yang, Yufan Yang, Yonglin He, Hongwu Qian. Structural basis for catalysis of human choline/ethanolamine phosphotransferase 1.
Nature communications.
2023 May; 14(1):2529. doi:
10.1038/s41467-023-38290-2. [PMID: 37137909] - Linda M Westermann, Ian D E A Lidbury, Chun-Yang Li, Ning Wang, Andrew R J Murphy, Maria Del Mar Aguilo Ferretjans, Mussa Quareshy, Muralidharan Shanmugan, Alberto Torcello-Requena, Eleonora Silvano, Yu-Zhong Zhang, Claudia A Blindauer, Yin Chen, David J Scanlan. Bacterial catabolism of membrane phospholipids links marine biogeochemical cycles.
Science advances.
2023 04; 9(17):eadf5122. doi:
10.1126/sciadv.adf5122. [PMID: 37126561] - Samantha G Scharenberg, Wentao Dong, Ali Ghoochani, Kwamina Nyame, Roni Levin-Konigsberg, Aswini R Krishnan, Eshaan S Rawat, Kaitlyn Spees, Michael C Bassik, Monther Abu-Remaileh. An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation.
Science advances.
2023 04; 9(16):eadf8966. doi:
10.1126/sciadv.adf8966. [PMID: 37075117] - Aisha Zaki, Shouqun Jiang, Saad Zaghloul, Talaat K El-Rayes, Ahmed A Saleh, Mahmoud Mostafa Azzam, Marco Ragni, Mahmoud Alagawany. Betaine as an alternative feed additive to choline and its effect on performance, blood parameters, and egg quality in laying hens rations.
Poultry science.
2023 Apr; 102(7):102710. doi:
10.1016/j.psj.2023.102710. [PMID: 37148572] - Shihan Zhou, Jing Liu, Yan Sun, Ping Xu, Jin Ling Liu, Suping Sun, Boran Zhu, Haoxin Wu. Dietary choline metabolite TMAO impairs cognitive function and induces hippocampal synaptic plasticity declining through the mTOR/P70S6K/4EBP1 pathway.
Food & function.
2023 Mar; ?(?):. doi:
10.1039/d2fo03874a. [PMID: 36883968] - Gabriel Dorighello, Michael McPhee, Katie Halliday, Graham Dellaire, NealeD Ridgway. Differential contributions of phosphotransferases CEPT1 and CHPT1 to phosphatidylcholine homeostasis and lipid droplet biogenesis.
The Journal of biological chemistry.
2023 Mar; ?(?):104578. doi:
10.1016/j.jbc.2023.104578. [PMID: 36871755]