1-nitronaphthalene (BioDeep_00000014825)

 

Secondary id: BioDeep_00000858388

human metabolite Volatile Flavor Compounds


代谢物信息卡片


alpha-Nitronaphthalene

化学式: C10H7NO2 (173.0476762)
中文名称: 1-硝基萘, 硝基萘
谱图信息: 最多检出来源 Homo sapiens(blood) 0.51%

分子结构信息

SMILES: C1=CC=C2C(=C1)C=CC=C2[N+](=O)[O-]
InChI: InChI=1S/C10H7NO2/c12-11(13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7H

描述信息

1-nitronaphthalene is also known as Nitrol
D009676 - Noxae > D002273 - Carcinogens

同义名列表

8 个代谢物同义名

alpha-Nitronaphthalene; Α-nitronaphthalene; a-Nitronaphthalene; 1-Nitronaphthalene; Nitronaphthalene; Nitrol; 1-Nitronaphthalene; 1-Nitronaphthalene



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Igor Linhart, Iveta Hanzlíková, Jaroslav Mráz, Šárka Dušková, Monika Tvrdíková, Hana Vachová. Novel aminoarylcysteine adducts in globin of rats dosed with naphthylamine and nitronaphthalene isomers. Archives of toxicology. 2021 01; 95(1):79-89. doi: 10.1007/s00204-020-02907-y. [PMID: 33156369]
  • Teresa W M Fan, Andrew N Lane, Richard M Higashi, Mohamed A Farag, Hong Gao, Michael Bousamra, Donald M Miller. Altered regulation of metabolic pathways in human lung cancer discerned by (13)C stable isotope-resolved metabolomics (SIRM). Molecular cancer. 2009 Jun; 8(?):41. doi: 10.1186/1476-4598-8-41. [PMID: 19558692]
  • David Kirkland, Carol Beevers. Induction of LacZ mutations in Muta Mouse can distinguish carcinogenic from non-carcinogenic analogues of diaminotoluenes and nitronaphthalenes. Mutation research. 2006 Sep; 608(1):88-96. doi: 10.1016/j.mrgentox.2006.05.004. [PMID: 16797226]
  • J Azmi, J Connelly, E Holmes, J K Nicholson, R F Shore, J L Griffin. Characterization of the biochemical effects of 1-nitronaphthalene in rats using global metabolic profiling by NMR spectroscopy and pattern recognition. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2005 Nov; 10(6):401-16. doi: 10.1080/13547500500309259. [PMID: 16308265]
  • Jeffrey W-D Foy, Robert A Schatz. Inhibition of rat respiratory-tract cytochrome P-450 activity after acute low-level m-xylene inhalation: role in 1-nitronaphthalene toxicity. Inhalation toxicology. 2004 Mar; 16(3):125-32. doi: 10.1080/08958370490270927. [PMID: 15204773]
  • Jean-Pierre Farant, David Ogilvie. Investigation of the presence of amino and nitro polycyclic aromatic hydrocarbons in a Söderberg primary aluminum smelter. AIHA journal : a journal for the science of occupational and environmental health and safety. 2002 Nov; 63(6):721-5. doi: 10.1080/15428110208984761. [PMID: 12570080]
  • M Gülden, S Mörchel, H Seibert. Factors influencing nominal effective concentrations of chemical compounds in vitro: cell concentration. Toxicology in vitro : an international journal published in association with BIBRA. 2001 Jun; 15(3):233-43. doi: 10.1016/s0887-2333(01)00008-x. [PMID: 11377096]
  • J S Halladay, J M Sauer, I G Sipes. Metabolism and disposition of [(14)C]1-nitronaphthalene in male Sprague-Dawley rats. Drug metabolism and disposition: the biological fate of chemicals. 1999 Dec; 27(12):1456-65. doi: NULL. [PMID: 10570027]
  • J M Sauer, R R Eversole, C L Lehmann, D E Johnson, L J Beuving. An ultrastructural evaluation of acute 1-nitronaphthalene induced hepatic and pulmonary toxicity in the rat. Toxicology letters. 1997 Jan; 90(1):19-27. doi: 10.1016/s0378-4274(96)03817-9. [PMID: 9020398]
  • J M Sauer, S B Hooser, I G Sipes. All-trans-retinol alteration of 1-nitronaphthalene-induced pulmonary and hepatic injury by modulation of associated inflammatory responses in the male Sprague-Dawley rat. Toxicology and applied pharmacology. 1995 Jul; 133(1):139-49. doi: 10.1006/taap.1995.1135. [PMID: 7597703]
  • R E Rasmussen, D H Do, T S Kim, L C Dearden. Comparative cytotoxicity of naphthalene and its monomethyl- and mononitro-derivatives in the mouse lung. Journal of applied toxicology : JAT. 1986 Feb; 6(1):13-20. doi: 10.1002/jat.2550060104. [PMID: 3958423]