Elastin (BioDeep_00000014758)
代谢物信息卡片
(2S)-1-[(2S)-2-[[2-[[(2S,3S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]acetyl]amino]-3-methylbutanoyl]-N-methylpyrrolidine-2-carboxamide
化学式: C27H48N6O6 (552.3635148)
中文名称: 猪源弹性蛋白
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC(C)C(C(=O)NCC(=O)NC(C(C)C)C(=O)N1CCCC1C(=O)NC)NC(=O)C(CC(C)C)NC(=O)C
InChI: InChI=1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:177837
- PubChem: 439221
- Metlin: METLIN65514
- MeSH: Elastin
- CAS: 9007-58-3
- KEGG: C00373
- PubChem: 3663
- KNApSAcK: 177837
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mikaela A Gray, Mariela R Rodriguez-Otero, Julie A Champion. Self-Assembled Recombinant Elastin and Globular Protein Vesicles with Tunable Properties for Diverse Applications.
Accounts of chemical research.
2024 May; 57(9):1227-1237. doi:
10.1021/acs.accounts.3c00694. [PMID: 38624000] - H M Gruchow, P Opdensteinen, J F Buyel. Membrane-based inverse-transition purification facilitates a rapid isolation of various spider-silk elastin-like polypeptide fusion proteins from extracts of transgenic tobacco.
Transgenic research.
2024 Apr; 33(1-2):21-33. doi:
10.1007/s11248-024-00375-z. [PMID: 38573429] - Chloé Lorion, Viviane Bardin, Sébastien Bonnet, Amandine Lopez-Gaydon, Boris Vogelgesang, Nicolas Bechetoille. Elastogenic potential and antisagging properties of a novel Murraya koenigii extract.
Journal of cosmetic dermatology.
2024 Mar; 23(3):1036-1044. doi:
10.1111/jocd.16059. [PMID: 37997524] - Sanpeng Xu, Qiong Wu, Zhe Tang, Ping Li. Identification and Analysis of DNA Methylation Inflammation-Related Key Genes in Intracerebral Hemorrhage.
Biochemical genetics.
2024 Feb; 62(1):395-412. doi:
10.1007/s10528-023-10430-9. [PMID: 37354351] - Luxuan Shen, Pei Zhou, Yue Min Wang, Zhixiong Zhu, Quan Yuan, Shuqin Cao, Jianshu Li. Supramolecular nanoparticles based on elastin-like peptides modified capsid protein as drug delivery platform with enhanced cancer chemotherapy efficacy.
International journal of biological macromolecules.
2024 Jan; 256(Pt 2):128107. doi:
10.1016/j.ijbiomac.2023.128107. [PMID: 38007030] - Shataakshi Dahal, Suraj Bastola, Anand Ramamurthi. JNK2 silencing lipid nanoparticles for elastic matrix repair.
Journal of biomedical materials research. Part A.
2023 Oct; ?(?):. doi:
10.1002/jbm.a.37618. [PMID: 37815147] - Linh Thi Thuy LE, Baek-Kyu Kim, Pham Ngoc Chien, Keon-Woo Choi, Hong-Bin Kim, Ui-Jae Hwang, Hyo Sun Han, Chan-Yeong Heo. Investigating the Anti-Aging Effects of Caviar Oil on Human Skin.
In vivo (Athens, Greece).
2023 Sep; 37(5):2078-2091. doi:
10.21873/invivo.13305. [PMID: 37652485] - Tobias Hedtke, Mathias Mende, Heiko Steenbock, Jürgen Brinckmann, Matthias Menzel, Wolfgang Hoehenwarter, Markus Pietzsch, Thomas Groth, Christian E H Schmelzer. Fabrication of Insoluble Elastin by Enzyme-Free Cross-Linking.
Macromolecular bioscience.
2023 Jul; ?(?):e2300203. doi:
10.1002/mabi.202300203. [PMID: 37441796] - Jingjing Ji, Md Shahadat Hossain, Emily N Krueger, Zhe Zhang, Shivangi Nangia, Britnie Carpentier, Mae Martel, Shikha Nangia, Davoud Mozhdehi. Lipidation Alters the Structure and Hydration of Myristoylated Intrinsically Disordered Proteins.
Biomacromolecules.
2023 03; 24(3):1244-1257. doi:
10.1021/acs.biomac.2c01309. [PMID: 36757021] - Woan-Ruoh Lee, Tse-Hung Huang, Sindy Hu, Ahmed Alalaiwe, Pei-Wen Wang, Pei-Chi Lo, Jia-You Fang, Shih-Chun Yang. Laser-assisted nanoparticle delivery to promote skin absorption and penetration depth of retinoic acid with the aim for treating photoaging.
International journal of pharmaceutics.
2022 Nov; 627(?):122162. doi:
10.1016/j.ijpharm.2022.122162. [PMID: 36122617] - Huong Thi Nguyen, Yun-Hyeok Choi, Chun Whan Choi, Joo-Won Suh, Jinhua Cheng. Enhanced anti-wrinkle activity of adlay bran fermented with Lactobacillus brevis MJM60390.
Journal of cosmetic dermatology.
2022 Nov; 21(11):6351-6362. doi:
10.1111/jocd.15290. [PMID: 35946116] - Wei-Wei Cai, Xiao-Meng Hu, Yu-Mei Wang, Chang-Feng Chi, Bin Wang. Bioactive Peptides from Skipjack Tuna Cardiac Arterial Bulbs: Preparation, Identification, Antioxidant Activity, and Stability against Thermal, pH, and Simulated Gastrointestinal Digestion Treatments.
Marine drugs.
2022 Sep; 20(10):. doi:
10.3390/md20100626. [PMID: 36286450] - Vanesa S Marín Viegas, Carolina G Ocampo, Fernando E Restucci, Florencia Vignolles, Flavia N Mazzini, Ángela M Candreva, Silvana Petruccelli. Synthesis of single-chain antibody fragment fused to the elastin-like polypeptide in Nicotiana benthamiana and its application in affinity precipitation of difficult to produce proteins.
Biotechnology and bioengineering.
2022 09; 119(9):2505-2517. doi:
10.1002/bit.28158. [PMID: 35689353] - Christian E H Schmelzer, Laurent Duca. Elastic fibers: formation, function, and fate during aging and disease.
The FEBS journal.
2022 07; 289(13):3704-3730. doi:
10.1111/febs.15899. [PMID: 33896108] - Gary L Pierce, Thais A Coutinho, Lyndsey E DuBose, Anthony J Donato. Is It Good to Have a Stiff Aorta with Aging? Causes and Consequences.
Physiology (Bethesda, Md.).
2022 05; 37(3):154-173. doi:
10.1152/physiol.00035.2021. [PMID: 34779281] - Barbara Tomasello, Giuseppe Antonio Malfa, Rosaria Acquaviva, Alfonsina La Mantia, Claudia Di Giacomo. Phytocomplex of a Standardized Extract from Red Orange (Citrus sinensis L. Osbeck) against Photoaging.
Cells.
2022 04; 11(9):. doi:
10.3390/cells11091447. [PMID: 35563752] - Jungwhoi Lee, Sung-Eun Jo, Jungsul Lee, Jae-Hoon Kim. An in vitro evaluation of luffa cylindrica stem sap in preadipocytes and dermal fibroblasts.
Biochemical and biophysical research communications.
2022 04; 599(?):100-105. doi:
10.1016/j.bbrc.2022.02.024. [PMID: 35180468] - Giulia Remaggi, Fulvio Barbaro, Giusy Di Conza, Giovanna Trevisi, Carlo Bergonzi, Roberto Toni, Lisa Elviri. Decellularization Detergents As Methodological Variables in Mass Spectrometry of Stromal Matrices.
Tissue engineering. Part C, Methods.
2022 04; 28(4):148-157. doi:
10.1089/ten.tec.2021.0191. [PMID: 35357965] - Natalia V Pozdniakova, Oxana V Ryabaya, Alevtina S Semkina, Vsevolod A Skribitsky, Alexei B Shevelev. Using ELP Repeats as a Scaffold for De Novo Construction of Gadolinium-Binding Domains within Multifunctional Recombinant Proteins for Targeted Delivery of Gadolinium to Tumour Cells.
International journal of molecular sciences.
2022 Mar; 23(6):. doi:
10.3390/ijms23063297. [PMID: 35328725] - Sonja Dragojevic, Lindsay Turner, Drazen Raucher. Circumventing Doxorubicin Resistance Using Elastin-like Polypeptide Biopolymer-Mediated Drug Delivery.
International journal of molecular sciences.
2022 Feb; 23(4):. doi:
10.3390/ijms23042301. [PMID: 35216417] - Federica Boraldi, Francesco Demetrio Lofaro, Andrea Cossarizza, Daniela Quaglino. The 'Elastic Perspective' of SARS-CoV-2 Infection and the Role of Intrinsic and Extrinsic Factors.
International journal of molecular sciences.
2022 Jan; 23(3):. doi:
10.3390/ijms23031559. [PMID: 35163482] - Jolinde van Strien, Hans Warmenhoven, Adrian Logiantara, Max Makurat, Lorenz Aglas, Athanasios Bethanis, Romain Leboux, Leonie van Rijt, J Andrew MacKay, Johannes W van Schijndel, Gregory Schneider, René Olsthoorn, Wim Jiskoot, Ronald van Ree, Alexander Kros. Bet v 1-displaying elastin-like polypeptide nanoparticles induce a strong humoral and weak CD4+ T-cell response against Bet v 1 in a murine immunogenicity model.
Frontiers in immunology.
2022; 13(?):1006776. doi:
10.3389/fimmu.2022.1006776. [PMID: 36275650] - Shizhu Zhao, Jingyuan Cao, Jianzhong Li, Xiaochun Yang, Peiyang Cao, Jingjing Lan, Guoyuan Lu. Association between serum elastin-derived peptides and abdominal aortic calcification in peritoneal dialysis patients: a cross-sectional study.
Renal failure.
2021 Dec; 43(1):860-868. doi:
10.1080/0886022x.2021.1918163. [PMID: 33993833] - Xiaoyuan Ma, R Thomas Collins, Ariana Goodman, Frank L Hanley, Robert Kirk Riemer. Pulmonary arteries of Williams syndrome patients exhibit altered serotonin metabolism genes and degenerated medial layer architecture.
Pediatric research.
2021 11; 90(5):1065-1072. doi:
10.1038/s41390-020-01359-5. [PMID: 33531674] - Fang-Zheng Wang, Hong Zhou, Hong-Yu Wang, Hang-Bing Dai, Qing Gao, Pei Qian, Ye-Bo Zhou. Hydrogen sulfide prevents arterial medial calcification in rats with diabetic nephropathy.
BMC cardiovascular disorders.
2021 10; 21(1):495. doi:
10.1186/s12872-021-02307-9. [PMID: 34645391] - Riley A Suhar, Laura M Marquardt, Shang Song, Hana Buabbas, Vanessa M Doulames, Patrik K Johansson, Katarina C Klett, Ruby E Dewi, Annika M K Enejder, Giles W Plant, Paul M George, Sarah C Heilshorn. Elastin-like Proteins to Support Peripheral Nerve Regeneration in Guidance Conduits.
ACS biomaterials science & engineering.
2021 09; 7(9):4209-4220. doi:
10.1021/acsbiomaterials.0c01053. [PMID: 34510904] - Manon Doué, Anaïs Okwieka, Alexandre Berquand, Laëtitia Gorisse, Pascal Maurice, Frédéric Velard, Christine Terryn, Michaël Molinari, Laurent Duca, Christine Piétrement, Philippe Gillery, Stéphane Jaisson. Carbamylation of elastic fibers is a molecular substratum of aortic stiffness.
Scientific reports.
2021 09; 11(1):17827. doi:
10.1038/s41598-021-97293-5. [PMID: 34497312] - Emmanuelle Gaillard, Sylvie Boisnic, Marie-Christine Branchet, Irène Lamour, Mayoura Keophiphath. Tasmannia lanceolata leaf extract alleviates stretch mark appearance in a randomized, placebo-controlled clinical trial in women and stimulates extracellular matrix synthesis in ex vivo human skin explants.
Journal of cosmetic dermatology.
2021 Jun; 20(6):1923-1932. doi:
10.1111/jocd.13780. [PMID: 33048421] - Wenting Cheng, Lei Zhou, Kai Hu, Dehua Kong, Wei Huang, Chuanjun Xu, Hao Li, Jinlong Li. Enzyme-Initiated Assembly of an Extracellular-Like Two-Dimensional Nanonetwork as a Method to Detect Procancerous Activity.
ACS sensors.
2021 05; 6(5):1815-1822. doi:
10.1021/acssensors.0c02651. [PMID: 33909412] - Hadi Ghasemi, Seyed Habibollah Mousavibahar, Mohammad Hashemnia, Jamshid Karimi, Iraj Khodadadi, Heidar Tavilani. Transitional cell carcinoma matrix stiffness regulates the osteopontin and YAP expression in recurrent patients.
Molecular biology reports.
2021 May; 48(5):4253-4262. doi:
10.1007/s11033-021-06440-8. [PMID: 34086159] - Xiaoying Wang, Vaideesh Parasaram, Saphala Dhital, Nasim Nosoudi, Shahd Hasanain, Brooks A Lane, Susan M Lessner, John F Eberth, Naren R Vyavahare. Systemic delivery of targeted nanotherapeutic reverses angiotensin II-induced abdominal aortic aneurysms in mice.
Scientific reports.
2021 04; 11(1):8584. doi:
10.1038/s41598-021-88017-w. [PMID: 33883612] - Elena Vega-Martín, Marta Gil-Ortega, Raquel González-Blázquez, Sara Benedito, Jesús Fernández-Felipe, Mariano Ruiz-Gayo, Nuria Del Olmo, Julie A Chowen, Laura M Frago, Beatriz Somoza, María S Fernández-Alfonso. Differential Deleterious Impact of Highly Saturated Versus Monounsaturated Fat Intake on Vascular Function, Structure, and Mechanics in Mice.
Nutrients.
2021 Mar; 13(3):. doi:
10.3390/nu13031003. [PMID: 33808927] - Jamarius P Waller, Stephen P Burke, Jason Engel, Alejandro R Chade, Gene L Bidwell. A dose-escalating toxicology study of the candidate biologic ELP-VEGF.
Scientific reports.
2021 03; 11(1):6216. doi:
10.1038/s41598-021-85693-6. [PMID: 33737643] - Bouke Boekema, Matthea Stoop, Marcel Vlig, Jos van Liempt, Ana Sobota, Magda Ulrich, Esther Middelkoop. Antibacterial and safety tests of a flexible cold atmospheric plasma device for the stimulation of wound healing.
Applied microbiology and biotechnology.
2021 Mar; 105(5):2057-2070. doi:
10.1007/s00253-021-11166-5. [PMID: 33587156] - Abhinav Parashar, Ophélie Gourgas, Kirk Lau, Jingjing Li, Lisa Muiznieks, Simon Sharpe, Elaine Davis, Marta Cerruti, Monzur Murshed. Elastin calcification in in vitro models and its prevention by MGP's N-terminal peptide.
Journal of structural biology.
2021 03; 213(1):107637. doi:
10.1016/j.jsb.2020.107637. [PMID: 33059036] - Andrea Heinz. Elastic fibers during aging and disease.
Ageing research reviews.
2021 03; 66(?):101255. doi:
10.1016/j.arr.2021.101255. [PMID: 33434682] - Ursula Schlötzer-Schrehardt, Chiea Chuen Khor. Pseudoexfoliation syndrome and glaucoma: from genes to disease mechanisms.
Current opinion in ophthalmology.
2021 Mar; 32(2):118-128. doi:
10.1097/icu.0000000000000736. [PMID: 33332884] - Xiaorong Lan, Qianting Zhao, Jiayi Zhang, Yang Lei, Yunbing Wang. A combination of hydrogen bonding and chemical covalent crosslinking to fabricate a novel swim-bladder-derived dry heart valve material yields advantageous mechanical and biological properties.
Biomedical materials (Bristol, England).
2021 02; 16(1):015014. doi:
10.1088/1748-605x/abb616. [PMID: 33586662] - Kayo Horie, Naoki Nanashima, Hayato Maeda, Toshiko Tomisawa, Indrawati Oey. Blackcurrant (Ribes nigrum L.) Extract Exerts Potential Vasculoprotective Effects in Ovariectomized Rats, Including Prevention of Elastin Degradation and Pathological Vascular Remodeling.
Nutrients.
2021 Feb; 13(2):. doi:
10.3390/nu13020560. [PMID: 33567796] - Jeremy Kiripolsky, Eileen M Kasperek, Chengsong Zhu, Quan-Zhen Li, Jia Wang, Guan Yu, Jill M Kramer. Immune-Intrinsic Myd88 Directs the Production of Antibodies With Specificity for Extracellular Matrix Components in Primary Sjögren's Syndrome.
Frontiers in immunology.
2021; 12(?):692216. doi:
10.3389/fimmu.2021.692216. [PMID: 34381449] - Jordan V Wang, Mitalee P Christman, Hao Feng, Georgina Ferzli, Hana Jeon, Roy G Geronemus. Tripeptide and hexapeptide topical as adjunct to nonablative fractional resurfacing for photodamage: A randomized split-face trial.
Journal of cosmetic dermatology.
2020 Dec; 19(12):3245-3250. doi:
10.1111/jocd.13795. [PMID: 33051975] - Konrad A Szychowski, Bartosz Skóra, Jakub Tobiasz, Jan Gmiński. Elastin-derived peptide VGVAPG decreases differentiation of mouse embryo fibroblast (3T3-L1) cells into adipocytes.
Adipocyte.
2020 12; 9(1):234-245. doi:
10.1080/21623945.2020.1770525. [PMID: 32463311] - Norbert Kiss, Luca Fésűs, Szabolcs Bozsányi, Flóra Szeri, Matthias Van Gils, Viktória Szabó, Anikó Ilona Nagy, Bernadett Hidvégi, Róbert Szipőcs, Ludovic Martin, Olivier Vanakker, Tamás Arányi, Béla Merkely, Norbert M Wikonkál, Márta Medvecz. Nonlinear optical microscopy is a novel tool for the analysis of cutaneous alterations in pseudoxanthoma elasticum.
Lasers in medical science.
2020 Oct; 35(8):1821-1830. doi:
10.1007/s10103-020-03027-w. [PMID: 32372237] - D Meza, W-H Li, I Seo, R Parsa, S Kaur, M Kizoulis, M D Southall. A blackberry-dill extract combination synergistically increases skin elasticity.
International journal of cosmetic science.
2020 Oct; 42(5):444-451. doi:
10.1111/ics.12644. [PMID: 32583541] - Yun-Li Zhao, Zi-Feng Yang, Bai-Fen Wu, Jian-Hua Shang, Ya-Ping Liu, Xin-Hua Wang, Xiao-Dong Luo. Indole alkaloids from leaves of Alstonia scholaris (L.) R. Br. protect against emphysema in mice.
Journal of ethnopharmacology.
2020 Sep; 259(?):112949. doi:
10.1016/j.jep.2020.112949. [PMID: 32387234] - Fangyu Shao, Yutong Miao, Yan Zhang, Lulu Han, Xiaolong Ma, Jiacheng Deng, Changtao Jiang, Wei Kong, Qingbo Xu, Juan Feng, Xian Wang. B cell-derived anti-beta 2 glycoprotein I antibody contributes to hyperhomocysteinaemia-aggravated abdominal aortic aneurysm.
Cardiovascular research.
2020 09; 116(11):1897-1909. doi:
10.1093/cvr/cvz288. [PMID: 31782769] - Thinhinane Hocine, Sebastien Blaise, Cathy Hachet, Alexandre Guillot, Herve Sartelet, Pascal Maurice, Amar Bennasroune, Laurent Martiny, Laurent Duca, Beatrice Romier-Crouzet, Hassan El Btaouri. Lactosylceramide induced by elastin-derived peptides decreases adipocyte differentiation.
Journal of physiology and biochemistry.
2020 Aug; 76(3):457-467. doi:
10.1007/s13105-020-00755-z. [PMID: 32592089] - Phoebe C R Parrish, Delong Liu, Russell H Knutsen, Charles J Billington, Robert P Mecham, Yi-Ping Fu, Beth A Kozel. Whole exome sequencing in patients with Williams-Beuren syndrome followed by disease modeling in mice points to four novel pathways that may modify stenosis risk.
Human molecular genetics.
2020 07; 29(12):2035-2050. doi:
10.1093/hmg/ddaa093. [PMID: 32412588] - Evangelia Gavgiotaki, George Filippidis, Vassilis Tsafas, Savvas Bovasianos, George Kenanakis, Vasilios Georgoulias, Maria Tzardi, Sofia Agelaki, Irene Athanassakis. Third Harmonic Generation microscopy distinguishes malignant cell grade in human breast tissue biopsies.
Scientific reports.
2020 07; 10(1):11055. doi:
10.1038/s41598-020-67857-y. [PMID: 32632110] - Asparuh Nikolov, Alexander Blazhev, Maria Tzekova, Konstantin Kostov, Nikola Popovski. Serum Levels of Antibodies to Advanced Glycation End Products in Patients with Type 2 Diabetes Mellitus and Hypertension.
Folia medica.
2020 Jun; 62(2):295-301. doi:
10.3897/folmed.62.e47788. [PMID: 32666760] - Ching-Chung Liang, Sheng-Wen Steven Shaw, Yu-Shien Ko, Yung-Hsin Huang, Tsong-Hai Lee. Effect of amniotic fluid stem cell transplantation on the recovery of bladder dysfunction in spinal cord-injured rats.
Scientific reports.
2020 06; 10(1):10030. doi:
10.1038/s41598-020-67163-7. [PMID: 32572272] - Preety Panwar, Tobias Hedtke, Andrea Heinz, Pierre-Marie Andrault, Wolfgang Hoehenwarter, David J Granville, Christian E H Schmelzer, Dieter Brömme. Expression of elastolytic cathepsins in human skin and their involvement in age-dependent elastin degradation.
Biochimica et biophysica acta. General subjects.
2020 05; 1864(5):129544. doi:
10.1016/j.bbagen.2020.129544. [PMID: 32007579] - Jacqueline Keuth, Yvonne Nitschke, Dennis Mulac, Kristina Riehemann, Frank Rutsch, Klaus Langer. Reversion of arterial calcification by elastin-targeted DTPA-HSA nanoparticles.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2020 May; 150(?):108-119. doi:
10.1016/j.ejpb.2020.03.007. [PMID: 32151731] - Danuta Kruk, Elzbieta Masiewicz, Milosz Wojciechowski, Malgorzata Florek-Wojciechowska, Lionel M Broche, David J Lurie. Slow dynamics of solid proteins - Nuclear magnetic resonance relaxometry versus dielectric spectroscopy.
Journal of magnetic resonance (San Diego, Calif. : 1997).
2020 05; 314(?):106721. doi:
10.1016/j.jmr.2020.106721. [PMID: 32276108] - Markian S Bahniuk, Abdullah K Alshememry, Larry D Unsworth. Human plasma protein adsorption to elastinlike polypeptide nanoparticles.
Biointerphases.
2020 03; 15(2):021007. doi:
10.1116/6.0000027. [PMID: 32228004] - Santosh Peddi, S Kenny Roberts, John Andrew MacKay. Nanotoxicology of an Elastin-like Polypeptide Rapamycin Formulation for Breast Cancer.
Biomacromolecules.
2020 03; 21(3):1091-1102. doi:
10.1021/acs.biomac.9b01431. [PMID: 31927993] - Anna Caroli, Andrea Remuzzi, Giuseppe Remuzzi. Does MRI trump pathology? A new era for staging and monitoring of kidney fibrosis.
Kidney international.
2020 03; 97(3):442-444. doi:
10.1016/j.kint.2019.10.008. [PMID: 31902648] - Md Shahadat Hossain, Xin Liu, Timothy I Maynard, Davoud Mozhdehi. Genetically Encoded Inverse Bolaamphiphiles.
Biomacromolecules.
2020 02; 21(2):660-669. doi:
10.1021/acs.biomac.9b01380. [PMID: 31855430] - Antonella D'Agostino, Anna Virginia Adriana Pirozzi, Rosario Finamore, Fabrizia Grieco, Massimiliano Minale, Chiara Schiraldi. Molecular Mechanisms at the Basis of Pharmaceutical Grade Triticum vulgare Extract Efficacy in Prompting Keratinocytes Healing.
Molecules (Basel, Switzerland).
2020 Jan; 25(3):. doi:
10.3390/molecules25030431. [PMID: 31972968] - David R Tyrpak, Yue Wang, Hugo Avila, Hao Guo, Runzhong Fu, Anh T Truong, Mincheol Park, Curtis T Okamoto, Sarah F Hamm-Alvarez, John Andrew MacKay. Caveolin elastin-like polypeptide fusions mediate temperature-dependent assembly of caveolar microdomains.
ACS biomaterials science & engineering.
2020 01; 6(1):198-204. doi:
10.1021/acsbiomaterials.9b01331. [PMID: 32542186] - Saphala Dhital, Naren R Vyavahare. Nanoparticle-based targeted delivery of pentagalloyl glucose reverses elastase-induced abdominal aortic aneurysm and restores aorta to the healthy state in mice.
PloS one.
2020; 15(3):e0227165. doi:
10.1371/journal.pone.0227165. [PMID: 32218565] - Hao Chai, ZhongHao Tao, YongChao Qi, HaoYu Qi, Wen Chen, YueYue Xu, LeiYang Zhang, HongWei Chen, Xin Chen. IKK Epsilon Deficiency Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice by Inhibiting Inflammation, Oxidative Stress, and Apoptosis.
Oxidative medicine and cellular longevity.
2020; 2020(?):3602824. doi:
10.1155/2020/3602824. [PMID: 32064021] - Jason E Engel, Maxx L Williams, Erika Williams, Camille Azar, Erin B Taylor, Gene L Bidwell, Alejandro R Chade. Recovery of Renal Function following Kidney-Specific VEGF Therapy in Experimental Renovascular Disease.
American journal of nephrology.
2020; 51(11):891-902. doi:
10.1159/000511260. [PMID: 33130676] - Konrad A Szychowski, Jan Gmiński. The Elastin-Derived Peptide VGVAPG Does Not Activate the Inflammatory Process in Mouse Cortical Astrocytes In Vitro.
Neurotoxicity research.
2020 Jan; 37(1):136-145. doi:
10.1007/s12640-019-00114-x. [PMID: 31691186] - Ophélie Gourgas, Gregory B Cole, Lisa D Muiznieks, Simon Sharpe, Marta Cerruti. Effect of the Ionic Concentration of Simulated Body Fluid on the Minerals Formed on Cross-Linked Elastin-Like Polypeptide Membranes.
Langmuir : the ACS journal of surfaces and colloids.
2019 11; 35(47):15364-15375. doi:
10.1021/acs.langmuir.9b02542. [PMID: 31729882] - Reza Heidari-Japelaghi, Raheem Haddad, Mostafa Valizadeh, Ebrahim Dorani-Uliaie, Mokhtar Jalali-Javaran. Elastin-like polypeptide fusions for high-level expression and purification of human IFN-γ in Escherichia coli.
Analytical biochemistry.
2019 11; 585(?):113401. doi:
10.1016/j.ab.2019.113401. [PMID: 31442384] - Jason E Engel, Erika Williams, Maxx L Williams, Gene L Bidwell, Alejandro R Chade. Targeted VEGF (Vascular Endothelial Growth Factor) Therapy Induces Long-Term Renal Recovery in Chronic Kidney Disease via Macrophage Polarization.
Hypertension (Dallas, Tex. : 1979).
2019 11; 74(5):1113-1123. doi:
10.1161/hypertensionaha.119.13469. [PMID: 31542966] - Beth A Kozel, Robert P Mecham. Elastic fiber ultrastructure and assembly.
Matrix biology : journal of the International Society for Matrix Biology.
2019 11; 84(?):31-40. doi:
10.1016/j.matbio.2019.10.002. [PMID: 31669522] - Kristine Janssen, Dan Li Lin, Brett Hanzlicek, Kangli Deng, Brian M Balog, Carl H van der Vaart, Margot S Damaser. Multiple doses of stem cells maintain urethral function in a model of neuromuscular injury resulting in stress urinary incontinence.
American journal of physiology. Renal physiology.
2019 10; 317(4):F1047-F1057. doi:
10.1152/ajprenal.00173.2019. [PMID: 31411077] - Yaping Ju, Hao Guo, Frances Yarber, Maria C Edman, Santosh Peddi, Srikanth Reddy Janga, J Andrew MacKay, Sarah F Hamm-Alvarez. Molecular Targeting of Immunosuppressants Using a Bifunctional Elastin-Like Polypeptide.
Bioconjugate chemistry.
2019 09; 30(9):2358-2372. doi:
10.1021/acs.bioconjchem.9b00462. [PMID: 31408605] - Tobias Hedtke, Christoph U Schräder, Andrea Heinz, Wolfgang Hoehenwarter, Jürgen Brinckmann, Thomas Groth, Christian E H Schmelzer. A comprehensive map of human elastin cross-linking during elastogenesis.
The FEBS journal.
2019 09; 286(18):3594-3610. doi:
10.1111/febs.14929. [PMID: 31102572] - Bahadir Simsek, Ufuk Çakatay. Could cyanogenic glycoside rich diet cause increased risk for carbamylation-induced protein damage in individuals with chronic inflammatory diseases?.
Medical hypotheses.
2019 Sep; 130(?):109275. doi:
10.1016/j.mehy.2019.109275. [PMID: 31383327] - Kyeong-Min Lee, Jung-Hee Kim, Eun-Sook Choi, Eunjoo Kim, Seong-Kyoon Choi, Won Bae Jeon. RGD-containing elastin-like polypeptide improves islet transplantation outcomes in diabetic mice.
Acta biomaterialia.
2019 08; 94(?):351-360. doi:
10.1016/j.actbio.2019.06.011. [PMID: 31200117] - Ophélie Gourgas, Lisa D Muiznieks, Dainelys Guadarrama Bello, Antonio Nanci, Simon Sharpe, Marta Cerruti. Cross-Linked Elastin-like Polypeptide Membranes as a Model for Medial Arterial Calcification.
Biomacromolecules.
2019 07; 20(7):2625-2636. doi:
10.1021/acs.biomac.9b00417. [PMID: 31244014] - Jeong Eun Kwon, Jaewon Lim, Ina Bang, Inhye Kim, Donghyuk Kim, Se Chan Kang. Fermentation product with new equol-producing Lactobacillus paracasei as a probiotic-like product candidate for prevention of skin and intestinal disorder.
Journal of the science of food and agriculture.
2019 Jul; 99(9):4200-4210. doi:
10.1002/jsfa.9648. [PMID: 30767231] - Changrim Lee, Hao Guo, Wannita Klinngam, Srikanth R Janga, Frances Yarber, Santosh Peddi, Maria C Edman, Nishant Tiwari, Siyu Liu, Stan G Louie, Sarah F Hamm-Alvarez, J Andrew MacKay. Berunda Polypeptides: Biheaded Rapamycin Carriers for Subcutaneous Treatment of Autoimmune Dry Eye Disease.
Molecular pharmaceutics.
2019 07; 16(7):3024-3039. doi:
10.1021/acs.molpharmaceut.9b00263. [PMID: 31095909] - Manohar Rebecca, Ramakrishnan Gayathri, Renganathan Bhuvanasundar, Krishnamoorthy Sripriya, Balekudaru Shantha, Narayanasamy Angayarkanni. Elastin modulation and modification by homocysteine: a key factor in the pathogenesis of Pseudoexfoliation syndrome?.
The British journal of ophthalmology.
2019 07; 103(7):985-992. doi:
10.1136/bjophthalmol-2018-312088. [PMID: 30249767] - Yeyzon Cruz, Efrén Muñoz, E Y Gomez-Pachón, Juan Morales-Corona, Jesús Olayo-Lortia, Roberto Olayo, Roberto Olayo-Valles. Electrospun PCL-protein scaffolds coated by pyrrole plasma polymerization.
Journal of biomaterials science. Polymer edition.
2019 07; 30(10):832-845. doi:
10.1080/09205063.2019.1603338. [PMID: 30943867] - Monica Wang. Measuring fibrosis without biopsies.
Nature reviews. Nephrology.
2019 07; 15(7):388. doi:
10.1038/s41581-019-0153-4. [PMID: 31000798] - Tamires Aparecida Bitencourt, Claudia Macedo, Matheus Eloy Franco, Marina Campos Rocha, Igor Sawasaki Moreli, Bruna Aline Micheloto Cantelli, Pablo Rodrigo Sanches, Rene Oliveira Beleboni, Iran Malavazi, Geraldo Aleixo Passos, Mozart Marins, Ana Lúcia Fachin. Trans-chalcone activity against Trichophyton rubrum relies on an interplay between signaling pathways related to cell wall integrity and fatty acid metabolism.
BMC genomics.
2019 May; 20(1):411. doi:
10.1186/s12864-019-5792-0. [PMID: 31117938] - Bon-Hee Gu, Justin C Choi, Ying H Shen, Li-Zhen Song, Michael E Scheurer, Amber Luong, Antony Rodriguez, Prescott Woodruff, Laura Koth, David B Corry, Farrah Kheradmand, Scott A LeMaire. Elastin-Specific Autoimmunity in Smokers With Thoracic Aortic Aneurysm and Dissection is Independent of Chronic Obstructive Pulmonary Disease.
Journal of the American Heart Association.
2019 04; 8(8):e011671. doi:
10.1161/jaha.118.011671. [PMID: 30957625] - Michelle Griffin, Deepak Kalaskar, Peter Butler. Argon plasma modified nanocomposite polyurethane scaffolds provide an alternative strategy for cartilage tissue engineering.
Journal of nanobiotechnology.
2019 Apr; 17(1):51. doi:
10.1186/s12951-019-0477-z. [PMID: 30954085] - Qinxue Sun, Maike Baues, Barbara M Klinkhammer, Josef Ehling, Sonja Djudjaj, Natascha I Drude, Christoph Daniel, Kerstin Amann, Rafael Kramann, Hyojin Kim, Julio Saez-Rodriguez, Ralf Weiskirchen, David C Onthank, Rene M Botnar, Fabian Kiessling, Jürgen Floege, Twan Lammers, Peter Boor. Elastin imaging enables noninvasive staging and treatment monitoring of kidney fibrosis.
Science translational medicine.
2019 04; 11(486):. doi:
10.1126/scitranslmed.aat4865. [PMID: 30944168] - Konrad A Szychowski, Jan Gmiński. Impact of elastin-derived VGVAPG peptide on bidirectional interaction between peroxisome proliferator-activated receptor gamma (Pparγ) and beta-galactosidase (β-Gal) expression in mouse cortical astrocytes in vitro.
Naunyn-Schmiedeberg's archives of pharmacology.
2019 04; 392(4):405-413. doi:
10.1007/s00210-018-1591-4. [PMID: 30511276] - Sarah Rank Rønnow, Lasse Løcke Langholm, Jannie Marie Bülow Sand, Jeppe Thorlacius-Ussing, Diana Julie Leeming, Tina Manon-Jensen, Ruth Tal-Singer, Bruce E Miller, Morten Asser Karsdal, Jørgen Vestbo. Specific elastin degradation products are associated with poor outcome in the ECLIPSE COPD cohort.
Scientific reports.
2019 03; 9(1):4064. doi:
10.1038/s41598-019-40785-2. [PMID: 30858579] - Julia Brangsch, Carolin Reimann, Jan O Kaufmann, Lisa C Adams, David C Onthank, Christa Thöne-Reineke, Simon P Robinson, Rebecca Buchholz, Uwe Karst, Rene M Botnar, Bernd Hamm, Marcus R Makowski. Concurrent Molecular Magnetic Resonance Imaging of Inflammatory Activity and Extracellular Matrix Degradation for the Prediction of Aneurysm Rupture.
Circulation. Cardiovascular imaging.
2019 03; 12(3):e008707. doi:
10.1161/circimaging.118.008707. [PMID: 30871334] - Charlotte Kawecki, Olivier Bocquet, Christian E H Schmelzer, Andrea Heinz, Christian Ihling, Amandine Wahart, Béatrice Romier, Amar Bennasroune, Sébastien Blaise, Christine Terryn, Kenneth J Linton, Laurent Martiny, Laurent Duca, Pascal Maurice. Identification of CD36 as a new interaction partner of membrane NEU1: potential implication in the pro-atherogenic effects of the elastin receptor complex.
Cellular and molecular life sciences : CMLS.
2019 Feb; 76(4):791-807. doi:
10.1007/s00018-018-2978-6. [PMID: 30498996] - Jeppe Thorlacius-Ussing, Stephanie Nina Kehlet, Sarah Rank Rønnow, Morten Asser Karsdal, Nicholas Willumsen. Non-invasive profiling of protease-specific elastin turnover in lung cancer: biomarker potential.
Journal of cancer research and clinical oncology.
2019 Feb; 145(2):383-392. doi:
10.1007/s00432-018-2799-x. [PMID: 30467633] - Samagya Banskota, Parisa Yousefpour, Nadia Kirmani, Xinghai Li, Ashutosh Chilkoti. Long circulating genetically encoded intrinsically disordered zwitterionic polypeptides for drug delivery.
Biomaterials.
2019 02; 192(?):475-485. doi:
10.1016/j.biomaterials.2018.11.012. [PMID: 30504081] - Yang Zong, Xiao Tan, Jingjing Xiao, Xinyu Zhang, Xiaoli Xia, Huaichang Sun. Half-life extension of porcine interferon-α by fusion to the IgG-binding domain of streptococcal G protein.
Protein expression and purification.
2019 01; 153(?):53-58. doi:
10.1016/j.pep.2018.08.012. [PMID: 30165247] - Saba Atefyekta, Maria Pihl, Chris Lindsay, Sarah C Heilshorn, Martin Andersson. Antibiofilm elastin-like polypeptide coatings: functionality, stability, and selectivity.
Acta biomaterialia.
2019 01; 83(?):245-256. doi:
10.1016/j.actbio.2018.10.039. [PMID: 30541700] - Hirona Kugo, Chie Miyamoto, Ayaka Sawaragi, Kiyoto Hoshino, Yuka Hamatani, Shinichi Matsumura, Yuri Yoshioka, Tatsuya Moriyama, Nobuhiro Zaima. Sesame Extract Attenuates the Degradation of Collagen and Elastin Fibers in the Vascular Walls of Nicotine-administered Mice.
Journal of oleo science.
2019; 68(1):79-85. doi:
10.5650/jos.ess18200. [PMID: 30606956] - Marija Kuna, Jamarius P Waller, Omar C Logue, Gene L Bidwell. Polymer size affects biodistribution and placental accumulation of the drug delivery biopolymer elastin-like polypeptide in a rodent pregnancy model.
Placenta.
2018 12; 72-73(?):20-27. doi:
10.1016/j.placenta.2018.10.005. [PMID: 30501877] - Daniele Pezzoli, Joseph Di Paolo, Heena Kumra, Giulia Fois, Gabriele Candiani, Dieter P Reinhardt, Diego Mantovani. Fibronectin promotes elastin deposition, elasticity and mechanical strength in cellularised collagen-based scaffolds.
Biomaterials.
2018 10; 180(?):130-142. doi:
10.1016/j.biomaterials.2018.07.013. [PMID: 30036726] - Esméralda Cicchetti, Leslie Duroure, Erell Le Borgne, Rémi Laville. Upregulation of Skin-Aging Biomarkers in Aged NHDF Cells by a Sucrose Ester Extract from the Agroindustrial Waste of Physalis peruviana Calyces.
Journal of natural products.
2018 09; 81(9):1946-1955. doi:
10.1021/acs.jnatprod.7b01069. [PMID: 30136843] - Christoph U Schräder, Andrea Heinz, Petra Majovsky, Berin Karaman Mayack, Jürgen Brinckmann, Wolfgang Sippl, Christian E H Schmelzer. Elastin is heterogeneously cross-linked.
The Journal of biological chemistry.
2018 09; 293(39):15107-15119. doi:
10.1074/jbc.ra118.004322. [PMID: 30108173] - Duy Tien Ta, Rosario Vanella, Michael A Nash. Bioorthogonal Elastin-like Polypeptide Scaffolds for Immunoassay Enhancement.
ACS applied materials & interfaces.
2018 Sep; 10(36):30147-30154. doi:
10.1021/acsami.8b10092. [PMID: 30125079] - Natasja Stæhr Gudmann, Tina Manon-Jensen, Jannie Marie Bülow Sand, Claudia Diefenbach, Shu Sun, Annette Danielsen, Morten Asser Karsdal, Diana Julie Leeming. Lung tissue destruction by proteinase 3 and cathepsin G mediated elastin degradation is elevated in chronic obstructive pulmonary disease.
Biochemical and biophysical research communications.
2018 09; 503(3):1284-1290. doi:
10.1016/j.bbrc.2018.07.038. [PMID: 30017196] - Daichi Nakagawa, Mario Zanaty, Joseph Hudson, Nahom Teferi, Daizo Ishii, Lauren Allan, Pascal Jabbour, Santiago Ortega-Gutierrez, Edgar A Samaniego, David M Hasan. Plasma Soluble Human Elastin Fragments as an Intra-Aneurysmal Localized Biomarker for Ruptured Intracranial Aneurysm.
Journal of the American Heart Association.
2018 09; 7(17):e010051. doi:
10.1161/jaha.118.010051. [PMID: 30371156]