Valacyclovir hydrochloride (BioDeep_00000014659)

   


代谢物信息卡片


Valacyclovir hydrochloride

化学式: C13H21ClN6O4 (360.13127360000004)
中文名称: 盐酸伐昔洛韦
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)C(C(=O)OCCOCN1C=NC2=C1N=C(NC2=O)N)N.Cl
InChI: 1H/t8-

描述信息

D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
C471 - Enzyme Inhibitor > C29575 - DNA Polymerase Inhibitor
C254 - Anti-Infective Agent > C281 - Antiviral Agent
Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W (50=2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422) [1][2][3][4][5].

同义名列表

3 个代谢物同义名

Valacyclovir hydrochloride; Valaciclovir hydrochloride; Valacyclovir (hydrochloride)



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • James Kirkland, Pathmanathan Suganthan. Valacyclovir-associated acute kidney injury. BMJ case reports. 2022 Jun; 15(6):. doi: 10.1136/bcr-2022-249552. [PMID: 35764333]
  • Elisabeth J Cohen, Judith S Hochman, Andrea B Troxel, Kathryn A Colby, Bennie H Jeng. Zoster Eye Disease Study: Rationale and Design. Cornea. 2022 May; 41(5):562-571. doi: 10.1097/ico.0000000000002743. [PMID: 35090154]
  • Obaidur Rehman, Sudesh Kumar Arya, Ujjwal Prakash Jha, Shifali Nayyar, Itisha Goel. Herpes Zoster Ophthalmicus After COVID-19 Vaccination: Chance Occurrence or More?. Cornea. 2022 Feb; 41(2):254-256. doi: 10.1097/ico.0000000000002881. [PMID: 34690265]
  • Narisa Ruenroengbun, Tunlanut Sapankaew, Kamolpat Chaiyakittisopon, Pakpoom Phoompoung, Thundon Ngamprasertchai. Efficacy and Safety of Antiviral Agents in Preventing Allograft Rejection Following CMV Prophylaxis in High-Risk Kidney Transplantation: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. Frontiers in cellular and infection microbiology. 2022; 12(?):865735. doi: 10.3389/fcimb.2022.865735. [PMID: 35433502]
  • V Faure-Bardon, J Fourgeaud, J Stirnemann, M Leruez-Ville, Y Ville. Secondary prevention of congenital cytomegalovirus infection with valacyclovir following maternal primary infection in early pregnancy. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. 2021 Oct; 58(4):576-581. doi: 10.1002/uog.23685. [PMID: 33998084]
  • J Schurder, H Lazareth, J Mrad, E Thervet, A Benachi, A J Vivanti. Acute kidney injury after valacyclovir administration for prevention of congenital cytomegalovirus infection. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. 2021 10; 58(4):636-637. doi: 10.1002/uog.23724. [PMID: 34182607]
  • Olus Uyar, Pier-Luc Plante, Jocelyne Piret, Marie-Christine Venable, Julie Carbonneau, Jacques Corbeil, Guy Boivin. A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis. Scientific reports. 2021 09; 11(1):18688. doi: 10.1038/s41598-021-98047-z. [PMID: 34548521]
  • David Brandariz-Nuñez, Marcelo Correas-Sanahuja, Sara Maya-Gallego, Isabel Martín Herranz. Neurotoxicity associated with acyclovir and valacyclovir: A systematic review of cases. Journal of clinical pharmacy and therapeutics. 2021 Aug; 46(4):918-926. doi: 10.1111/jcpt.13464. [PMID: 34146428]
  • Tsuneaki Kenzaka, Kazuma Sugimoto, Ken Goda, Hozuka Akita. Acute kidney injury and acyclovir-associated encephalopathy after administration of valacyclovir in an elderly person with normal renal function: A case report and literature review. Medicine. 2021 May; 100(21):e26147. doi: 10.1097/md.0000000000026147. [PMID: 34032768]
  • Vignesh Kumar, Priyanka Narayanan, Seema Shetty, Afsal P Mohammed. Lower motor neuron facial palsy in a postnatal mother with COVID-19. BMJ case reports. 2021 Mar; 14(3):. doi: 10.1136/bcr-2020-240267. [PMID: 33649026]
  • Caroline Opene, Maxwell A Fung, Marc Silverstein. Orf progressiva: giant progressive and destructive infections in the immunocompromised. Dermatology online journal. 2021 Jan; 27(1):. doi: NULL. [PMID: 33560789]
  • Li-Min Liang, Jun-Jie Zhou, Feng Xu, Pei-Hua Liu, Lan Qin, Li Liu, Xiao-Dong Liu. Diabetes downregulates peptide transporter 1 in the rat jejunum: possible involvement of cholate-induced FXR activation. Acta pharmacologica Sinica. 2020 Nov; 41(11):1465-1475. doi: 10.1038/s41401-020-0408-4. [PMID: 32341465]
  • Douglas S Ruhl, Marc H Hohman. An Example of Employing the Principles of Bioethics to Medical Decision Making in the COVID-19 Era. The Laryngoscope. 2020 11; 130(11):2688-2689. doi: 10.1002/lary.28896. [PMID: 32535910]
  • Pallavi Prasad, Dinesh Khullar, Nimish Gupta, Rahul Grover, Gagandeep Chhabra, Kunal Raj Gandhi, Sagar Gupta, Sahil Bagai. Retransplantation after post transplant lymphoproliferative disorder: overcoming the obstacles!. CEN case reports. 2020 08; 9(3):200-203. doi: 10.1007/s13730-020-00455-z. [PMID: 32016786]
  • Tatsuki Noguchi, Takeshi Nishikawa, Soichiro Ishihara. Rectocolic and colocolic fistulas accompanied by cytomegalovirus infection: Two case reports. Asian journal of surgery. 2020 Jul; 43(7):783-784. doi: 10.1016/j.asjsur.2020.03.004. [PMID: 32199669]
  • H Tabaja, S L Sharara, Y Abi Aad, N Beydoun, S Tabbal, A Makki, R Mahfouz, S S Kanj. Varicella zoster virus infection of the central nervous system in a tertiary care center in Lebanon. Medecine et maladies infectieuses. 2020 May; 50(3):280-287. doi: 10.1016/j.medmal.2019.08.005. [PMID: 31526545]
  • Shi Bai, Justin A Maykel, Michelle X Yang. Inflammatory pseudotumor associated with HSV infection of rectal vascular endothelium in a patient with HIV: a case report and literature review. BMC infectious diseases. 2020 Mar; 20(1):234. doi: 10.1186/s12879-020-04960-5. [PMID: 32192456]
  • D P Devanand, Howard Andrews, William C Kreisl, Qolamreza Razlighi, Anne Gershon, Yaakov Stern, Akiva Mintz, Thomas Wisniewski, Edward Acosta, Julianna Pollina, Mariasofia Katsikoumbas, Karen L Bell, Gregory H Pelton, Deborah Deliyannides, K M Prasad, Edward D Huey. Antiviral therapy: Valacyclovir Treatment of Alzheimer's Disease (VALAD) Trial: protocol for a randomised, double-blind,placebo-controlled, treatment trial. BMJ open. 2020 02; 10(2):e032112. doi: 10.1136/bmjopen-2019-032112. [PMID: 32034019]
  • Tomas Reischig, Martin Kacer, Ondrej Hes, Jana Machova, Jana Nemcova, Daniel Lysak, Pavel Jindra, Kristyna Pivovarcikova, Stanislav Kormunda, Mirko Bouda. Cytomegalovirus prevention strategies and the risk of BK polyomavirus viremia and nephropathy. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2019 09; 19(9):2457-2467. doi: 10.1111/ajt.15507. [PMID: 31220412]
  • Eun Jeong Ko, Ji Hyun Yu, Chul Woo Yang, Byung Ha Chung. Usefulness of valacyclovir prophylaxis for cytomegalovirus infection after anti-thymocyte globulin as rejection therapy. The Korean journal of internal medicine. 2019 Mar; 34(2):375-382. doi: 10.3904/kjim.2017.040. [PMID: 29237252]
  • Dimitrios Chanouzas, Michael Sagmeister, Sian Faustini, Peter Nightingale, Alex Richter, Charles J Ferro, Matthew David Morgan, Paul Moss, Lorraine Harper. Subclinical Reactivation of Cytomegalovirus Drives CD4+CD28null T-Cell Expansion and Impaired Immune Response to Pneumococcal Vaccination in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. The Journal of infectious diseases. 2019 01; 219(2):234-244. doi: 10.1093/infdis/jiy493. [PMID: 30102389]
  • J Boix-Vilanova, M C Montis, A Giacaman, O Corral-Magaña, A Bauza. Herpes vegetans in a human immunodeficiency virus-negative kidney transplant patient. Clinical and experimental dermatology. 2019 01; 44(1):92-94. doi: 10.1111/ced.13748. [PMID: 30259552]
  • Archana Chacko, Amaldoss M J Newton. Synthesis and Characterization of Valacyclovir HCl Hybrid Solid Lipid Nanoparticles by Using Natural Oils. Recent patents on drug delivery & formulation. 2019; 13(1):46-61. doi: 10.2174/1872211313666190304142129. [PMID: 30836929]
  • Yoshiaki Ohtsu, Yoko Susaki, Kiyoshi Noguchi. Absorption, Distribution, Metabolism, and Excretion of the Novel Helicase-Primase Inhibitor, Amenamevir (ASP2151), in Rodents. European journal of drug metabolism and pharmacokinetics. 2018 Dec; 43(6):693-706. doi: 10.1007/s13318-018-0481-y. [PMID: 29748821]
  • Tomas Reischig, Martin Kacer, Petra Hruba, Hana Hermanova, Ondrej Hes, Daniel Lysak, Stanislav Kormunda, Mirko Bouda. Less renal allograft fibrosis with valganciclovir prophylaxis for cytomegalovirus compared to high-dose valacyclovir: a parallel group, open-label, randomized controlled trial. BMC infectious diseases. 2018 Nov; 18(1):573. doi: 10.1186/s12879-018-3493-y. [PMID: 30442095]
  • Takashi Yoshimura, Tatsuya Kawasaki, Ayumi Shirota, Masashi Saeki, Yuki Okada, Hiroshi Okada. Valacyclovir-induced Neurotoxicity in a Patient with a Preserved Renal Function. Internal medicine (Tokyo, Japan). 2018 Nov; 57(21):3213-3216. doi: 10.2169/internalmedicine.0403-17. [PMID: 29877263]
  • Le Sun, Chao Wang, Youxi Zhang. A physiologically based pharmacokinetic model for valacyclovir established based on absolute expression quantity of hPEPT1 and its application. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2018 Oct; 123(?):560-568. doi: 10.1016/j.ejps.2018.07.057. [PMID: 30081070]
  • Jian Shi, Yongjun Hu, David E Smith, Hao-Jie Zhu. A sensitive liquid chromatography-tandem mass spectrometry method for the quantification of valacyclovir and its metabolite acyclovir in mouse and human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2018 Aug; 1092(?):447-452. doi: 10.1016/j.jchromb.2018.06.040. [PMID: 29945109]
  • Marta Ferreira, Cristina Vega, Begoña Rivas, Rafael Selgas. Acute renal failure and severe neurotoxicity after unintentional overdose of valacyclovir in a geriatric population: A case report. Nefrologia. 2018 May; 38(3):323-325. doi: 10.1016/j.nefro.2017.05.007. [PMID: 29523376]
  • Jian Huang, Jinhua Huang, Yaping Xiang, Lihua Gao, Yizhi Pan, Jianyun Lu. [Topical ozone therapy: An innovative solution to patients with herpes zoster]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. 2018 Feb; 43(2):168-172. doi: 10.11817/j.issn.1672-7347.2018.02.011. [PMID: 29559601]
  • Zhihua Yue, Jinhai Shi, Haona Li, Huiyi Li. Association between Concomitant Use of Acyclovir or Valacyclovir with NSAIDs and an Increased Risk of Acute Kidney Injury: Data Mining of FDA Adverse Event Reporting System. Biological & pharmaceutical bulletin. 2018 Feb; 41(2):158-162. doi: 10.1248/bpb.b17-00547. [PMID: 29187701]
  • Yanfang Han, Qing Guo, Shaozhen Mai, Liangchun Wang, Min Xu, Guozhen Tan. Acute renal injury induced by oral valacyclovir. European journal of dermatology : EJD. 2018 02; 28(1):122-123. doi: 10.1684/ejd.2017.3189. [PMID: 29336319]
  • Bei Yang, David E Smith. In Silico Absorption Analysis of Valacyclovir in Wildtype and Pept1 Knockout Mice Following Oral Dose Escalation. Pharmaceutical research. 2017 Nov; 34(11):2349-2361. doi: 10.1007/s11095-017-2242-z. [PMID: 28770489]
  • Antoine Rousseau, David Boutolleau, Karine Titier, Tristan Bourcier, Christophe Chiquet, Michel Weber, Joseph Colin, Julie Gueudry, Mohamed M'Garrech, Bahram Bodaghi, Sonia Burrel, Henri Agut, Claire Deback, Marc Labetoulle. Recurrent herpetic keratitis despite antiviral prophylaxis: A virological and pharmacological study. Antiviral research. 2017 Oct; 146(?):205-212. doi: 10.1016/j.antiviral.2017.09.013. [PMID: 28939476]
  • Lara K Maxwell, Bradford G Bentz, Lyndi L Gilliam, Jerry W Ritchey, Nicola Pusterla, R Eberle, Todd C Holbrook, Dianne McFarlane, Grant B Rezabek, James Meinkoth, Chase Whitfield, Carla L Goad, George P Allen. Efficacy of the early administration of valacyclovir hydrochloride for the treatment of neuropathogenic equine herpesvirus type-1 infection in horses. American journal of veterinary research. 2017 Oct; 78(10):1126-1139. doi: 10.2460/ajvr.78.10.1126. [PMID: 28945127]
  • Bhanu Prasad, Mark McIsaac, Julie Toppings. Valacyclovir-associated neurotoxicity treated with intensification of peritoneal dialysis. BMJ case reports. 2017 07; 2017(?):. doi: 10.1136/bcr-2017-220678. [PMID: 28765478]
  • Rakesh Kumar, V R Sinha. Lipid Nanocarrier: an Efficient Approach Towards Ocular Delivery of Hydrophilic Drug (Valacyclovir). AAPS PharmSciTech. 2017 Apr; 18(3):884-894. doi: 10.1208/s12249-016-0575-2. [PMID: 27368921]
  • Scott D Schoenberger, Stephen J Kim, Jennifer E Thorne, Prithvi Mruthyunjaya, Steven Yeh, Sophie J Bakri, Justis P Ehlers. Diagnosis and Treatment of Acute Retinal Necrosis: A Report by the American Academy of Ophthalmology. Ophthalmology. 2017 03; 124(3):382-392. doi: 10.1016/j.ophtha.2016.11.007. [PMID: 28094044]
  • Y Anne Pak, Amanda J Long, William F Annes, Jennifer W Witcher, Mary Pat Knadler, Mosun A Ayan-Oshodi, Malcolm I Mitchell, Phillip Leese, Kathleen M Hillgren. In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1. Drug metabolism and disposition: the biological fate of chemicals. 2017 02; 45(2):137-144. doi: 10.1124/dmd.116.071118. [PMID: 27895114]
  • Erica Andersen-Nissen, Joanne T Chang, Katherine K Thomas, Devin Adams, Connie Celum, Jorge Sanchez, Robert W Coombs, M Juliana McElrath, Jared M Baeten. Herpes Simplex Virus Suppressive Therapy in Herpes Simplex Virus-2/Human Immunodeficiency Virus-1 Coinfected Women Is Associated With Reduced Systemic CXCL10 But Not Genital Cytokines. Sexually transmitted diseases. 2016 12; 43(12):761-764. doi: 10.1097/olq.0000000000000523. [PMID: 27832025]
  • Alexander K Schuster, Björn C Harder, Frank C Schlichtenbrede, Marc N Jarczok, Jonas Tesarz. Valacyclovir versus acyclovir for the treatment of herpes zoster ophthalmicus in immunocompetent patients. The Cochrane database of systematic reviews. 2016 11; 11(?):CD011503. doi: 10.1002/14651858.cd011503.pub2. [PMID: 27841441]
  • Mitsuyoshi Nakatani, Mitsuhiro Tsukino, Ryosuke Takahashi, Akio Ikeda. Periodic synchronous discharge occurred in an elderly with acute valacyclovir-associated encephalopathy. Rinsho shinkeigaku = Clinical neurology. 2016 07; 56(7):504-7. doi: 10.5692/clinicalneurol.cn-000892. [PMID: 27356736]
  • Dimitrios Chanouzas, Lovesh Dyall, Peter Nightingale, Charles Ferro, Paul Moss, Matthew David Morgan, Lorraine Harper. Valaciclovir to prevent Cytomegalovirus mediated adverse modulation of the immune system in ANCA-associated vasculitis (CANVAS): study protocol for a randomised controlled trial. Trials. 2016 07; 17(1):338. doi: 10.1186/s13063-016-1482-2. [PMID: 27450392]
  • Hanan Polansky, Adrian Javaherian, Edan Itzkovitz. Clinical study in genital herpes: natural Gene-Eden-VIR/Novirin versus acyclovir, valacyclovir, and famciclovir. Drug design, development and therapy. 2016; 10(?):2713-22. doi: 10.2147/dddt.s112852. [PMID: 27621592]
  • Marilyn Chavannes, Rohit S Doad, Gurinder J S Doad. Valacyclovir and acute renal failure. Journal of the Medical Association of Georgia. 2016; 105(3):14. doi: NULL. [PMID: 29809345]
  • M Kacer, L Kielberger, M Bouda, T Reischig. Valganciclovir versus valacyclovir prophylaxis for prevention of cytomegalovirus: an economic perspective. Transplant infectious disease : an official journal of the Transplantation Society. 2015 Jun; 17(3):334-41. doi: 10.1111/tid.12383. [PMID: 25824586]
  • Christophe Vanpouille, Andrea Lisco, Jean-Charles Grivel, Leda C Bassit, Robert C Kauffman, Jorge Sanchez, Raymond F Schinazi, Michael M Lederman, Benigno Rodriguez, Leonid Margolis. Valacyclovir Decreases Plasma HIV-1 RNA in HSV-2 Seronegative Individuals: A Randomized Placebo-Controlled Crossover Trial. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2015 Jun; 60(11):1708-14. doi: 10.1093/cid/civ172. [PMID: 25740794]
  • Tomas Reischig, Martin Kacer, Pavel Jindra, Ondrej Hes, Daniel Lysak, Mirko Bouda. Randomized trial of valganciclovir versus valacyclovir prophylaxis for prevention of cytomegalovirus in renal transplantation. Clinical journal of the American Society of Nephrology : CJASN. 2015 Feb; 10(2):294-304. doi: 10.2215/cjn.07020714. [PMID: 25424991]
  • Shahzaib Nabi, Pushpinderdeep Kahlon, Mariella Goggins, Anita Patel. VZV encephalitis following successful treatment of CMV infection in a patient with kidney transplant. BMJ case reports. 2014 Dec; 2014(?):. doi: 10.1136/bcr-2014-206655. [PMID: 25465457]
  • Mary J Burton, Alan Penman, Imran Sunesara, Brendan M McGuire, Edward W Hook. A pilot study examining the safety and tolerability of valacyclovir in veterans with hepatitis C virus/herpes simplex virus type 2 coinfection. The American journal of the medical sciences. 2014 Dec; 348(6):455-9. doi: 10.1097/maj.0000000000000321. [PMID: 25163019]
  • Dhara Chaudhari, David Ginn. Valacyclovir-associated neurotoxicity in peritoneal dialysis patients. American journal of therapeutics. 2014 Nov; 21(6):e215-7. doi: 10.1097/mjt.0b013e318289bae9. [PMID: 23528373]
  • Zhihua Yue, Jinhai Shi, Pengli Jiang, He Sun. Acute kidney injury during concomitant use of valacyclovir and loxoprofen: detecting drug-drug interactions in a spontaneous reporting system. Pharmacoepidemiology and drug safety. 2014 Nov; 23(11):1154-9. doi: 10.1002/pds.3626. [PMID: 24788910]
  • Joanna Brydak-Godowska, Piotr Borkowski, Szymon Szczepanik, Joanna Moneta-Wielgoś, Dariusz Kęcik. Clinical manifestation of self-limiting acute retinal necrosis. Medical science monitor : international medical journal of experimental and clinical research. 2014 Oct; 20(?):2088-96. doi: 10.12659/msm.890469. [PMID: 25356955]
  • Alison C Roxby, Claire Atkinson, Kristjana Asbjörnsdóttir, Carey Farquhar, James N Kiarie, Alison L Drake, Anna Wald, Michael Boeckh, Barbra Richardson, Vincent Emery, Grace John-Stewart, Jennifer A Slyker. Maternal valacyclovir and infant cytomegalovirus acquisition: a randomized controlled trial among HIV-infected women. PloS one. 2014; 9(2):e87855. doi: 10.1371/journal.pone.0087855. [PMID: 24504006]
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  • Johanna Barón, Sonia Herrero-Velázquez, Marina Ruiz-Piñero, M Isabel Pedraza, Silvia Rojo-Rello, Ángel Luis Guerrero-Peral. [Encephalitis due to the Epstein-Barr virus: a description of a clinical case and review of the literature]. Revista de neurologia. 2013 Nov; 57(10):451-4. doi: NULL. [PMID: 24203667]
  • Tae Joon Yi, Sharon Walmsley, Leah Szadkowski, Janet Raboud, Nimerta Rajwans, Brett Shannon, Sachin Kumar, Kevin C Kain, Rupert Kaul, Darrell H S Tan. A randomized controlled pilot trial of valacyclovir for attenuating inflammation and immune activation in HIV/herpes simplex virus 2-coinfected adults on suppressive antiretroviral therapy. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2013 Nov; 57(9):1331-8. doi: 10.1093/cid/cit539. [PMID: 23946220]
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  • Tara Perti, Misty Saracino, Jared M Baeten, Christine Johnston, Kurt Diem, Negusse Ocbamichael, Meei-Li Huang, Stacy Selke, Amalia Magaret, Lawrence Corey, Anna Wald. High-dose valacyclovir decreases plasma HIV-1 RNA more than standard-dose acyclovir in persons coinfected with HIV-1 and HSV-2: a randomized crossover trial. Journal of acquired immune deficiency syndromes (1999). 2013 Jun; 63(2):201-8. doi: 10.1097/qai.0b013e3182928eea. [PMID: 23542637]
  • Fredrik Sund, Gunnar Tufveson, Bernd Döhler, Gerhard Opelz, Britt-Marie Eriksson. Clinical outcome with low-dose valacyclovir in high-risk renal transplant recipients: a 10-year experience. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2013 Mar; 28(3):758-65. doi: 10.1093/ndt/gfs531. [PMID: 23243043]
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  • Elisabeth M Hodson, Maleeka Ladhani, Angela C Webster, Giovanni F M Strippoli, Jonathan C Craig. Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients. The Cochrane database of systematic reviews. 2013 Feb; ?(2):CD003774. doi: 10.1002/14651858.cd003774.pub4. [PMID: 23450543]
  • P Zhang, W Wang, L Zhang, S F Li, L B Guan, L Q Dong, S Zhou, P Yu. Prophylaxis of human cytomegalovirus infection in renal transplant patients with valacyclovir and ganciclovir. Acta virologica. 2013; 57(3):375-7. doi: NULL. [PMID: 24020766]
  • Badal Shah, Todd Lafleur, Aicheng Chen. Carbon nanotube based electrochemical sensor for the sensitive detection of valacyclovir. Faraday discussions. 2013; 164(?):135-46. doi: 10.1039/c3fd00023k. [PMID: 24466662]
  • Chrysoula Pipili, Kostas Pantelias, Edmond Deda, Pandelis Tsiamalos, Evaggelos Kostis, Eirini Grapsa. Intensification of peritoneal dialysis improves valacyclovir neurotoxicity. Renal failure. 2013; 35(2):289-90. doi: 10.3109/0886022x.2012.743914. [PMID: 23176110]
  • Elizabeth Chiang, Dmitry Pyatetsky. Acute retinal necrosis secondary to varicella zoster virus in an immunosuppressed post-kidney transplant patient. Clinical medicine & research. 2012 Nov; 10(4):240-1. doi: 10.3121/cmr.2012.1091. [PMID: 22997354]
  • Tomas Reischig, Petra Hribova, Pavel Jindra, Ondrej Hes, Mirko Bouda, Vladislav Treska, Ondrej Viklicky. Long-term outcomes of pre-emptive valganciclovir compared with valacyclovir prophylaxis for prevention of cytomegalovirus in renal transplantation. Journal of the American Society of Nephrology : JASN. 2012 Sep; 23(9):1588-97. doi: 10.1681/asn.2012010100. [PMID: 22917575]
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