8-Isoprostaglandin F2a (BioDeep_00000014525)

 

Secondary id: BioDeep_00001874467

human metabolite Endogenous blood metabolite


代谢物信息卡片


(5Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]cyclopentyl]hept-5-enoic acid

化学式: C20H34O5 (354.24061140000003)
中文名称: 8-异前列烷
谱图信息: 最多检出来源 Homo sapiens(lipidomics) 5.85%

分子结构信息

SMILES: C([C@@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)CCCCC)/C=C\CCCC(O)=O
InChI: InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16-,17+,18-,19+/m0/s1

描述信息

8-Isoprostaglandin F2a is an isoprostane and a potent renal vasoconstrictor. Isoprostanes are prostaglandin-like compounds that are produced in vivo in humans by a noncyclooxygenase mechanism involving free radical-catalyzed peroxidation of arachidonic acid. The formation of these prostanoids proceeds through bicyclic endoperoxide intermediates that are then reduced to form ring isoprostanes. Of considerable interest is that, in contradistinction to cyclooxygenase-derived prostaglandins, isoprostanes have been shown to be initially formed in situ, esterified to phospholipids, and subsequently released preformed, presumably by phospholipases. The fact that prostanoids are produced in vivo by a noncyclooxygenase mechanism is of considerable interest from a biochemical perspective. However, this may also be associated with biological ramifications since it has been shown that these compounds are capable of exerting potent biological activity. (PMID: 7825845, 17012140). Prostaglandins are eicosanoids. The eicosanoids consist of the prostaglandins (PGs), thromboxanes (TXs), leukotrienes (LTs), and lipoxins (LXs). The PGs and TXs are collectively identified as prostanoids. Prostaglandins were originally shown to be synthesized in the prostate gland, thromboxanes from platelets (thrombocytes), and leukotrienes from leukocytes, hence the derivation of their names. All mammalian cells except erythrocytes synthesize eicosanoids. These molecules are extremely potent, able to cause profound physiological effects at very dilute concentrations. All eicosanoids function locally at the site of synthesis, through receptor-mediated G-protein linked signalling pathways. 8-iso-prostaglandin F2A is a biomarker for the consumption of offal meat.
8-Isoprostaglandin F2a is an isoprostane and a potent renal vasoconstrictor. Isoprostanes are prostaglandin-like compounds that are produced in vivo in humans by a noncyclooxygenase mechanism involving free radical-catalyzed peroxidation of arachidonic acid. The formation of these prostanoids proceeds through bicyclic endoperoxide intermediates that are then reduced to form ring isoprostanes. Of considerable interest is that, in contradistinction to cyclooxygenase-derived prostaglandins, isoprostanes have been shown to be initially formed in situ, esterified to phospholipids, and subsequently released preformed, presumably by phospholipases. The fact that prostanoids are produced in vivo by a noncyclooxygenase mechanism is of considerable interest from a biochemical perspective. However, this may also be associated with biological ramifications since it has been shown that these compounds are capable of exerting potent biological activity. (PMID: 7825845, 17012140). 8-iso-prostaglandin F2A is a biomarker for the consumption of offal meat.
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents

同义名列表

44 个代谢物同义名

(5Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]cyclopentyl]hept-5-enoic acid; (5Z,13E,15S)-9alpha,11alpha,15-Trihydroxy-8beta-prosta-5,13-dien-1-Oic acid; (5Z,13E,15S)-9alpha,11alpha,15-Trihydroxy-8beta-prosta-5,13-dien-1-Oate; 6S,12S,14R-trihydroxy-5Z,9E-prostadienoic acid-cyclo[11S,15R]; 9S,11R,15S-trihydroxy-5Z,13E-prostadienoic acid-cyclo[8S,12R]; 9S,11R,15S-trihydroxy-5Z,13E-prostadienoic acid; 9,11,15-Trihydroxy-prosta-5,13-dien-1-Oic acid; 9,11,15-Trihydroxy prosta-5,13-dien-1-Oic acid; 9S,11R,15S-Trihydroxy-5Z,13E-prostadienoate; 9,11,15-Trihydroxy-prosta-5,13-dien-1-Oate; 9,11,15-Trihydroxy prosta-5,13-dien-1-Oate; Isoprostaglandin F2alpha type-III; (9S,11R,15S)-15-F2-IsoP[8S,12R]; 8-iso Prostaglandin F2α 8-Epi-prostaglandin F2alpha; 8-Epiprostaglandin F2alpha; 8-Isoprostaglandin F2alpha; 8-Epi-prostaglandin F2α; 8-Epi-prostaglandin F2a; 8-Epiprostaglandin F2a; 8-Epiprostaglandin F2α; 8-Isoprostaglandin F2a; 8-Isoprostaglandin F2α; 15-F(2t)-Isoprostane; 8-F(2t)-Isoprostane; 8-Iso-PGF2alpha-III; 15-F2t-Isoprostane; 8-iso-PGF2α; 8-iso-PGF(2alpha); 8-Epi PGF-2alpha; 8-Epi-PGF2 alpha; 8-Epi-PGF2alpha; 8-Iso-PGF2a-III; 8-iso-PGF2alpha; 8-Iso-PGF2α-III; 15-F(2t)-IsoP; 8-Isoprostane; 15-F2t-IsoP; 8-Iso-PGF2α; 8-Epi-PGF2a; 8-Epi-PGF2α; 8-Iso-PGF2a; FA 20:3;O3; 8-IsoP



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Lin Ma, Dongxiao Sun, Guangli Xiu, Philip Lazarus, Anil Vachani, Trevor M Penning, Alexander S Whitehead, Joshua E Muscat. Quantification of Plasma 8-Isoprostane by High-Performance Liquid Chromatography with Tandem Mass Spectrometry in a Case-Control Study of Lung Cancer. International journal of environmental research and public health. 2022 09; 19(19):. doi: 10.3390/ijerph191912488. [PMID: 36231826]
  • Heike Braun, Michael Hauke, Robert Eckenstaler, Markus Petermann, Anne Ripperger, Niklas Kühn, Edzard Schwedhelm, Beatrice Ludwig-Kraus, Frank Bernhard Kraus, Virginie Dubourg, Alma Zernecke, Barbara Schreier, Michael Gekle, Ralf A Benndorf. The F2-isoprostane 8-iso-PGF2α attenuates atherosclerotic lesion formation in Ldlr-deficient mice - Potential role of vascular thromboxane A2 receptors. Free radical biology & medicine. 2022 05; 185(?):36-45. doi: 10.1016/j.freeradbiomed.2022.04.010. [PMID: 35470061]
  • Rani Sauriasari, Afina Irsyania Zulfa, Andisyah Putri Sekar, Nuriza Ulul Azmi, Xian Wen Tan, Eiji Matsuura. Role of urinary H2O2, 8-iso-PGF2α, and serum oxLDL/β2GP1 complex in the diabetic kidney disease. PloS one. 2022; 17(4):e0263113. doi: 10.1371/journal.pone.0263113. [PMID: 35381015]
  • Abu Saleh Md Moin, Manjula Nandakumar, Hassan Kahal, Thozhukat Sathyapalan, Stephen L Atkin, Alexandra E Butler. Heat Shock-Related Protein Responses and Inflammatory Protein Changes Are Associated with Mild Prolonged Hypoglycemia. Cells. 2021 11; 10(11):. doi: 10.3390/cells10113109. [PMID: 34831332]
  • Ning Ma, Yujian Zhang, Binbin Liu, Xiaojiao Jia, Rui Wang, Qiang Lu. Associations of plasma 8-iso-prostaglandin F2αlevels with fasting blood glucose (FBG) and intra-abdominal fat (IAF) area in various Glycometabolism populations. BMC endocrine disorders. 2021 Oct; 21(1):215. doi: 10.1186/s12902-021-00879-3. [PMID: 34711211]
  • Camila Kochi, Ankita Salvi, Fatin Atrooz, Samina Salim. Simulated vehicle exhaust exposure induces sex-dependent behavioral deficits in rats. Environmental toxicology and pharmacology. 2021 Aug; 86(?):103660. doi: 10.1016/j.etap.2021.103660. [PMID: 33865999]
  • Aliaa Abdelmoniem Bedeir Eita, Azza Mohamed Zaki, Sabah Abdelhady Mahmoud. Serum 8-isoprostane levels in patients with resistant oral lichen planus before and after treatment with lycopene: a randomized clinical trial. BMC oral health. 2021 07; 21(1):343. doi: 10.1186/s12903-021-01711-z. [PMID: 34266435]
  • Victor M Petrone-Garcia, Raquel Lopez-Arellano, Gabriela Rodríguez Patiño, Miriam Aide Castillo Rodríguez, Daniel Hernandez-Patlan, Bruno Solis-Cruz, Xochitl Hernandez-Velasco, Fernando Alba-Hurtado, Christine N Vuong, Inkar Castellanos-Huerta, Guillermo Tellez-Isaias. Curcumin reduces enteric isoprostane 8-iso-PGF2α and prostaglandin GF2α in specific pathogen-free Leghorn chickens challenged with Eimeria maxima. Scientific reports. 2021 06; 11(1):11609. doi: 10.1038/s41598-021-90679-5. [PMID: 34078952]
  • Emma Fletcher, Paul M Gordon. Obesity-induced alterations to the immunoproteasome: a potential link to intramuscular lipotoxicity. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 2021 May; 46(5):485-493. doi: 10.1139/apnm-2020-0655. [PMID: 33186056]
  • Hyunok Choi, Miroslav Dostal, Anna Pastorkova, Pavel Rossner, Radim J Sram. Airborne Benzo[a]Pyrene may contribute to divergent Pheno-Endotypes in children. Environmental health : a global access science source. 2021 04; 20(1):40. doi: 10.1186/s12940-021-00711-4. [PMID: 33836759]
  • Guang Yang, Christopher Qian, Chao Zhang, Yong Bao, Meng-Yue Liu, Fei Jiang, Wei Li, Yong Liu, Ya Ke, Zhong-Ming Qian. Hepcidin attenuates the iron-mediated secondary neuronal injury after intracerebral hemorrhage in rats. Translational research : the journal of laboratory and clinical medicine. 2021 03; 229(?):53-68. doi: 10.1016/j.trsl.2020.09.002. [PMID: 32932001]
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  • Andrew C Stokes, Wubin Xie, Anna E Wilson, Hanqi Yang, Olusola A Orimoloye, Alyssa F Harlow, Jessica L Fetterman, Andrew P DeFilippis, Emelia J Benjamin, Rose Marie Robertson, Aruni Bhatnagar, Naomi M Hamburg, Michael J Blaha. Association of Cigarette and Electronic Cigarette Use Patterns With Levels of Inflammatory and Oxidative Stress Biomarkers Among US Adults: Population Assessment of Tobacco and Health Study. Circulation. 2021 02; 143(8):869-871. doi: 10.1161/circulationaha.120.051551. [PMID: 33390037]
  • Sandra Amalie Dybos, Åge Winje Brustad, Toril Rolfseng, Solveig Kvam, Oddrun Elise Olsen, Jostein Halgunset, Haakon Skogseth. RNA-Integrity and 8-Isoprostane Levels Are Stable in Prostate Tissue Samples Upon Long-Term Storage at -80°C. Biopreservation and biobanking. 2021 Feb; 19(1):2-10. doi: 10.1089/bio.2019.0136. [PMID: 32865438]
  • Yusuke Miyazaki, Tatsuro Nakamura, Shinya Takenouchi, Akane Hayashi, Keisuke Omori, Takahisa Murata. Urinary 8-iso PGF2α and 2,3-dinor-8-iso PGF2α can be indexes of colitis-associated colorectal cancer in mice. PloS one. 2021; 16(1):e0245292. doi: 10.1371/journal.pone.0245292. [PMID: 33503019]
  • Yuehuan Wu, Cong Fu, Bing Li, Chang Liu, Zhi He, Xing-Er Li, Ailing Wang, Genshan Ma, Yuyu Yao. Bradykinin Protects Human Endothelial Progenitor Cells from High-Glucose-Induced Senescence through B2 Receptor-Mediated Activation of the Akt/eNOS Signalling Pathway. Journal of diabetes research. 2021; 2021(?):6626627. doi: 10.1155/2021/6626627. [PMID: 34557552]
  • Stephanie Hadley, Debora Cañizo Vazquez, Miriam Lopez Abad, Stefano Congiu, Dmytro Lushchencov, Marta Camprubí Camprubí, Joan Sanchez-de-Toledo. Oxidative stress response in children undergoing cardiac surgery: Utility of the clearance of isoprostanes. PloS one. 2021; 16(7):e0250124. doi: 10.1371/journal.pone.0250124. [PMID: 34228731]
  • Tomas Almeida-Becerril, Maricela Rodríguez-Cruz, Juan Raúl Sánchez-González, Marco Antonio Villaldama-Soriano, Salvador Atilano-Miguel, Judith Villa-Morales, Alan Cárdenas-Conejo, René Cárdenas-Vázquez. Circulating markers of oxidative stress are associated with a muscle injury in patients with muscular dystrophy Duchenne. Brain & development. 2021 Jan; 43(1):111-120. doi: 10.1016/j.braindev.2020.06.013. [PMID: 32654955]
  • Qiyou Tan, Jixuan Ma, Min Zhou, Dongming Wang, Bin Wang, Xiuquan Nie, Ge Mu, Xiaomin Zhang, Weihong Chen. Heavy metals exposure, lipid peroxidation and heart rate variability alteration: Association and mediation analyses in urban adults. Ecotoxicology and environmental safety. 2020 Dec; 205(?):111149. doi: 10.1016/j.ecoenv.2020.111149. [PMID: 32829210]
  • Fan Liang, Xiaona Huo, Wei Wang, Yan Li, Jun Zhang, Yan Feng, Yan Wang. Association of bisphenol A or bisphenol S exposure with oxidative stress and immune disturbance among unexplained recurrent spontaneous abortion women. Chemosphere. 2020 Oct; 257(?):127035. doi: 10.1016/j.chemosphere.2020.127035. [PMID: 32702804]
  • Min Zhou, Lili Xiao, Shijie Yang, Bin Wang, Tingming Shi, Aijun Tan, Xing Wang, Ge Mu, Weihong Chen. Cross-sectional and longitudinal associations between urinary zinc and lung function among urban adults in China. Thorax. 2020 09; 75(9):771-779. doi: 10.1136/thoraxjnl-2019-213909. [PMID: 32631935]
  • Orhan Lepara, Asija Zaciragic, Almir Fajkic, Alma Dzubur Kulenovic, Amela Dervisevic, Amina Valjevac, Emina Kiseljakovic, Saida Ibragic. Peripheral 8-iso-PGF2α as a Biomarker in Bosnian Patients with Alzheimer's Disease and Vascular Dementia. Psychiatria Danubina. 2020 Sep; 32(3-4):389-394. doi: 10.24869/psyd.2020.389. [PMID: 33370737]
  • Yu-Lien Tsai, Chih-Wei Liu, Chien-Fu Hsu, Chia-Chang Huang, Ming-Wei Lin, Shiang-Fen Huang, Tzu-Hao Li, Kuei-Chuan Lee, Yun-Cheng Hsieh, Ying-Ying Yang, Tzung-Yan Lee, Hsuan-Miao Liu, Yi-Hsiang Huang, Ming-Chih Hou, Han-Chieh Lin. Obeticholic acid ameliorates hepatorenal syndrome in ascitic cirrhotic rats by down-regulating the renal 8-iso-PGF2α-activated COX-TXA2 pathway. Clinical science (London, England : 1979). 2020 08; 134(15):2055-2073. doi: 10.1042/cs20200452. [PMID: 32725149]
  • Serpil Ersan, Burhanettin Cigdem, Deniz Bakir, H Okan Dogan. Determination of levels of oxidative stress and nitrosative stress in patients with epilepsy. Epilepsy research. 2020 08; 164(?):106352. doi: 10.1016/j.eplepsyres.2020.106352. [PMID: 32446164]
  • M Graille, P Wild, J-J Sauvain, M Hemmendinger, I Guseva Canu, N B Hopf. Urinary 8-isoprostane as a biomarker for oxidative stress. A systematic review and meta-analysis. Toxicology letters. 2020 Aug; 328(?):19-27. doi: 10.1016/j.toxlet.2020.04.006. [PMID: 32320775]
  • Chan-Hee Lee, Hyun-Woo Shin, Dong-Gu Shin. Impact of Oxidative Stress on Long-Term Heart Rate Variability: Linear Versus Non-Linear Heart Rate Dynamics. Heart, lung & circulation. 2020 Aug; 29(8):1164-1173. doi: 10.1016/j.hlc.2019.06.726. [PMID: 31495726]
  • F Fanti, F Vincenti, C Montesano, M Serafini, D Compagnone, M Sergi. dLLME-μSPE extraction coupled to HPLC-ESI-MS/MS for the determination of F2α-IsoPs in human urine. Journal of pharmaceutical and biomedical analysis. 2020 Jul; 186(?):113302. doi: 10.1016/j.jpba.2020.113302. [PMID: 32353681]
  • Limin Cao, Yun Zhou, Aijun Tan, Tingming Shi, Chunmei Zhu, Lili Xiao, Zhuang Zhang, Shijie Yang, Ge Mu, Xing Wang, Dongming Wang, Jixuan Ma, Weihong Chen. Oxidative damage mediates the association between polycyclic aromatic hydrocarbon exposure and lung function. Environmental health : a global access science source. 2020 07; 19(1):75. doi: 10.1186/s12940-020-00621-x. [PMID: 32616062]
  • Javier Diaz-Castro, Carlota Muriel-Neyra, Rafael Martin-Masot, Jorge Moreno-Fernandez, José Maldonado, Teresa Nestares. Oxidative stress, DNA stability and evoked inflammatory signaling in young celiac patients consuming a gluten-free diet. European journal of nutrition. 2020 Jun; 59(4):1577-1584. doi: 10.1007/s00394-019-02013-5. [PMID: 31144026]
  • Gong Su, Ming-Xi Gao, Gen-Ling Shi, Xi-Xi Dai, Wei-Feng Yao, Tao Zhang, Shao-Wei Zhuang. Effect of 1,5-anhydroglucitol levels on culprit plaque rupture in diabetic patients with acute coronary syndrome. Cardiovascular diabetology. 2020 05; 19(1):71. doi: 10.1186/s12933-020-01045-0. [PMID: 32473648]
  • Yara Shoman, Pascal Wild, Maud Hemmendinger, Melanie Graille, Jean-Jacques Sauvain, Nancy B Hopf, Irina Guseva Canu. Reference Ranges of 8-Isoprostane Concentrations in Exhaled Breath Condensate (EBC): A Systematic Review and Meta-Analysis. International journal of molecular sciences. 2020 May; 21(11):. doi: 10.3390/ijms21113822. [PMID: 32481492]
  • Inger-Lise Steffensen, Hubert Dirven, Stephan Couderq, Arthur David, Shereen Cynthia D'Cruz, Mariana F Fernández, Vicente Mustieles, Andrea Rodríguez-Carrillo, Tim Hofer. Bisphenols and Oxidative Stress Biomarkers-Associations Found in Human Studies, Evaluation of Methods Used, and Strengths and Weaknesses of the Biomarkers. International journal of environmental research and public health. 2020 05; 17(10):. doi: 10.3390/ijerph17103609. [PMID: 32455625]
  • Kira Trares, Xīn Gào, Laura Perna, Dan Rujescu, Hannah Stocker, Tobias Möllers, Konrad Beyreuther, Hermann Brenner, Ben Schöttker. Associations of urinary 8-iso-prostaglandin F2α levels with all-cause dementia, Alzheimer's disease, and vascular dementia incidence: results from a prospective cohort study. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2020 05; 16(5):804-813. doi: 10.1002/alz.12081. [PMID: 32281305]
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  • Rahana Abd Rahman, Padma Murthi, Harmeet Singh, Seshini Gurungsinghe, Bryan Leaw, Joanne C Mockler, Rebecca Lim, Euan M Wallace. Hydroxychloroquine Mitigates the Production of 8-Isoprostane and Improves Vascular Dysfunction: Implications for Treating Preeclampsia. International journal of molecular sciences. 2020 Apr; 21(7):. doi: 10.3390/ijms21072504. [PMID: 32260307]
  • Catherine Chase Lerro, Gabriella Andreotti, Jason Yy Wong, Aaron Blair, Nathaniel Rothman, Laura E Beane Freeman. 2,4-D exposure and urinary markers of oxidative DNA damage and lipid peroxidation: a longitudinal study. Occupational and environmental medicine. 2020 04; 77(4):276-280. doi: 10.1136/oemed-2019-106267. [PMID: 31996474]
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  • Joshua J Todd, Tokunbor A Lawal, Jessica W Witherspoon, Irene C Chrismer, Muslima S Razaqyar, Monal Punjabi, Jeffrey S Elliott, Fatoumata Tounkara, Anna Kuo, Monique O Shelton, Carolyn Allen, Mary M Cosgrove, Melody Linton, Darren Michael, Minal S Jain, Melissa Waite, Bart Drinkard, Paul G Wakim, James J Dowling, Carsten G Bönnemann, Magalie Emile-Backer, Katherine G Meilleur. Randomized controlled trial of N-acetylcysteine therapy for RYR1-related myopathies. Neurology. 2020 03; 94(13):e1434-e1444. doi: 10.1212/wnl.0000000000008872. [PMID: 31941795]
  • Giulia Squillacioti, Valeria Bellisario, Amelia Grosso, Federica Ghelli, Pavilio Piccioni, Elena Grignani, Angelo Corsico, Roberto Bono. Formaldehyde, Oxidative Stress, and FeNO in Traffic Police Officers Working in Two Cities of Northern Italy. International journal of environmental research and public health. 2020 03; 17(5):. doi: 10.3390/ijerph17051655. [PMID: 32143339]
  • Casilda Olveira, Eva García-Escobar, Esperanza Doña, Francisco J Palenque, Nuria Porras, Antonio Dorado, Ana María Godoy, Elezahara Rubio-Martín, Francisco-Javier Bermúdez-Silva, Silvana Y Romero-Zerbo, Gemma Rojo Martínez, Rocío Martín-Valero, José Abuín Fernández, Gabriel Olveira. Oxidative and inflammatory effects of pulmonary rehabilitation in patients with bronchiectasis. A prospective, randomized study. Nutricion hospitalaria. 2020 Feb; 37(1):6-13. doi: 10.20960/nh.02763. [PMID: 31960695]
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  • Ben Schöttker, Yang Xuan, Xīn Gào, Ankita Anusruti, Hermann Brenner. Oxidatively Damaged DNA/RNA and 8-Isoprostane Levels Are Associated With the Development of Type 2 Diabetes at Older Age: Results From a Large Cohort Study. Diabetes care. 2020 01; 43(1):130-136. doi: 10.2337/dc19-1379. [PMID: 31653645]
  • Yahaya Muhammad, Yamuna Kani Aminu, Abdurrahman Elfulaty Ahmad, Sani Iliya, Nuruddeen Muhd, Mohammed Yahaya, Aminu Sale Mustapha, Abdulkhabir Tahiru, Sulaiman Saeed Abdulkadir, Jamila Suleiman Ibrahim, Abdulmalik Binji Ahmad, Idris Yahaya Muhammad, Zaharaddeen Shehu, Abdulrahman Yakubu, Bashir Kabir Muhd, Armaya'u Ahmed, Umar Abubakar Faruk. An elevated 8-isoprostaglandin F2 alpha (8-iso-PGF2α) in COVID-19 subjects co-infected with malaria. The Pan African medical journal. 2020; 37(?):78. doi: 10.11604/pamj.2020.37.78.25100. [PMID: 33244341]
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