Iminodiacetate (IDA) (BioDeep_00000013126)

 

Secondary id: BioDeep_00001868205

human metabolite PANOMIX_OTCML-2023 blood metabolite Volatile Flavor Compounds


代谢物信息卡片


Iminodiacetic acid, calcium salt (1:1)

化学式: C4H7NO4 (133.0375062)
中文名称: 亚氨基二乙酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.12%

Reviewed

Last reviewed on 2024-09-14.

Cite this Page

Iminodiacetate (IDA). BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/iminodiacetate_(ida) (retrieved 2024-11-23) (BioDeep RN: BioDeep_00000013126). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C(C(=O)O)NCC(=O)O
InChI: InChI=1S/C4H7NO4/c6-3(7)1-5-2-4(8)9/h5H,1-2H2,(H,6,7)(H,8,9)

描述信息

Iminodiacetic acid (IDA) is a dicarboxylic acid amine. It is a strongly acidic compound that is very water soluble. It naturally exists as a white powder. IDA is food by-product or intermediate produced via the reaction of glycine with acrylamide through the heating, baking or frying of carbohydrate-rich foods such as potatoes (PMID: 25212154). Acrylamide is typically produced through a Maillard reaction (a heating reaction) of asparagine and various reducing sugars in plant-derived foods (PMID: 12368844). Concentrations of IDA are reduced in the plasma of individuals with autism (PMID: 33087514) and elevated in individuals with acute respiratory distress syndrome (ARDS) (PMID: 30779905). In addition to its role in metabolism, IDA has many industrial applications or roles. For instance, it is an important intermediate in the manufacture the herbicide glyphosate. IDA is also used in capillary electrophoresis for modulating peptide mobility and can be used as a precursor for the manufacture of the indicator xylenol orange. The iminodiacetate anion can act as a tridentate ligand to form a metal complex with two, fused, five membered chelate rings. The proton on the nitrogen atom can be replaced by a carbon atom of a polymer to create an ion-exchange resin, such as chelex 100. Iminodiacetic acid is used in HIDA (hepatobiliary iminodiacetic acid) scans or cholescintigraphy scans, that employ the radionuclide Technetium 99m, to diagnose several diseases in the liver, gallbladder and bile duct.
Iminodiacetic acid (IDA) is an polyamino carboxylic acid. The iminodiacetate anion can act as a tridentate ligand to form a metal complex with two, fused, five membered chelate rings. The proton on the nitrogen atom can be replaced by a carbon atom of a polymer to create an ion-exchange resin, such as chelex 100.
D064449 - Sequestering Agents > D002614 - Chelating Agents
Iminodiacetic acid (IDA) is a chelating agent that strongly binds transition metals[1]. Iminodiacetic acid can be used for removal of toxic metal ions from water[2]. Iminodiacetic acid can serve as a biomarker to potentially predict the severity of ARDS (acute respiratory distress syndrome)[3].

同义名列表

26 个代谢物同义名

Iminodiacetic acid, calcium salt (1:1); 2-[(Carboxymethyl)amino]acetic acid; Iminodiacetic acid, disodium salt; Iminodiacetic acid, sodium salt; 2-[(Carboxymethyl)amino]acetate; N-(Carboxymethyl)- glycine; 2,2-Azanediyldiacetic acid; N-(Carboxymethyl)glycine; Bis(carboxymethyl)amine; 2,2-Iminodiacetic acid; 2,2-Azanediyldiacetate; Iminobis(acetic acid); Iminodiethanoic acid; IMINODIACETIC ACID; 2,2-Iminodiacetate; Aminodiacetic acid; Imidodiacetic acid; Iminobis(acetate); Iminodiethanoate; Aminodiacetate; Iminodiacetate; Diglycocoll; Diglykokoll; Diglycine; IDA; Iminodiacetic acid



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ashish Khaparde, S Lokesh Kumar, M A Vijayalakshmi, Kishore K R Tetala. A conjoint multi metal-ion iminodiacetic acid monolith microfluidic chip for structural-based protein pre-fractionation. Electrophoresis. 2021 12; 42(24):2647-2655. doi: 10.1002/elps.202100288. [PMID: 34687221]
  • Muhammad Salman Sajid, Shafaq Saleem, Fahmida Jabeen, Batool Fatima, M Zulfikar, Muhammad Naeem Ashiq, Habtom W Ressom, Tara Louise Pukala, Muhammad Najam-Ul-Haq. Iminodiacetic acid (IDA)-generated mesoporous nanopolymer: a template to relate surface area, hydrophilicity, and glycopeptides enrichment. Mikrochimica acta. 2021 11; 188(12):417. doi: 10.1007/s00604-021-05074-8. [PMID: 34762162]
  • Meng Wang, Huifang Ma, Quan Chi, Qin Li, Ming Li, Huijuan Zhang, Chunya Li, Huaifang Fang. A monolithic copolymer prepared from N-(4-vinyl)-benzyl iminodiacetic acid, divinylbenzene and N,N'-methylene bisacrylamide for preconcentration of cadmium(II) and cobalt(II) from biological samples prior to their determination by ICP-MS. Mikrochimica acta. 2019 07; 186(8):537. doi: 10.1007/s00604-019-3656-6. [PMID: 31317277]
  • Magdalena Markowicz-Piasecka, Agata Skupień, Elżbieta Mikiciuk-Olasik, Joanna Sikora. Biocompatibility Studies of Gadolinium Complexes with Iminodiacetic Acid Derivatives. Biological trace element research. 2019 Jun; 189(2):426-436. doi: 10.1007/s12011-018-1496-6. [PMID: 30215189]
  • Wenjuan Zhang, Liyan Jiang, Li Fu, Qiong Jia. Selective enrichment of glycopeptides based on copper tetra(N-carbonylacrylic) aminephthalocyanine and iminodiacetic acid functionalized polymer monolith. Journal of separation science. 2019 Mar; 42(5):1037-1044. doi: 10.1002/jssc.201801030. [PMID: 30593720]
  • Haizhu Lin, Xi Shao, Yan Lu, Chunhui Deng. Preparation of iminodiacetic acid functionalized silica capillary trap column for on-column selective enrichment of N-linked glycopeptides. Talanta. 2018 Oct; 188(?):499-506. doi: 10.1016/j.talanta.2018.06.031. [PMID: 30029404]
  • Mengfan Zhai, Feng Ma, Junying Li, Binbin Wan, Ning Yu. Preparation and properties of cryogel based on poly(hydroxypropyl methacrylate). Journal of biomaterials science. Polymer edition. 2018 08; 29(12):1401-1425. doi: 10.1080/09205063.2018.1464263. [PMID: 29667520]
  • Muhammad Raznisyafiq Razak, Nor Azah Yusof, Mohammad Jelas Haron, Norazowa Ibrahim, Faruq Mohammad, Sazlinda Kamaruzaman, Hamad A Al-Lohedan. Iminodiacetic acid modified kenaf fiber for waste water treatment. International journal of biological macromolecules. 2018 Jun; 112(?):754-760. doi: 10.1016/j.ijbiomac.2018.02.035. [PMID: 29428390]
  • Anna Laura Capriotti, Chiara Cavaliere, Francesca Ferraris, Valentina Gianotti, Michele Laus, Susy Piovesana, Katia Sparnacci, Riccardo Zenezini Chiozzi, Aldo Laganà. New Ti-IMAC magnetic polymeric nanoparticles for phosphopeptide enrichment from complex real samples. Talanta. 2018 Feb; 178(?):274-281. doi: 10.1016/j.talanta.2017.09.010. [PMID: 29136822]
  • Jiaojiao Wang, Rui Zhang, Xiaxia Yang, Xiaoyan Liu, Haixia Zhang. Facile synthesis of copper(II)-decorated functional mesoporous material for specific adsorption of histidine-rich proteins. Talanta. 2018 Jan; 176(?):308-317. doi: 10.1016/j.talanta.2017.08.016. [PMID: 28917756]
  • Magdalena Markowicz-Piasecka, Piotr Dębski, Elżbieta Mikiciuk-Olasik, Joanna Sikora. Synthesis and Biocompatibility Studies of New Iminodiacetic Acid Derivatives. Molecules (Basel, Switzerland). 2017 Dec; 22(12):. doi: 10.3390/molecules22122265. [PMID: 29258275]
  • Baolong Xie, Huan Zhang, Xi Li, Xiaoyan Dong, Yan Sun. Iminodiacetic Acid-Modified Human Serum Albumin: A Multifunctional Agent against Metal-Associated Amyloid β-Protein Aggregation and Cytotoxicity. ACS chemical neuroscience. 2017 10; 8(10):2214-2224. doi: 10.1021/acschemneuro.7b00128. [PMID: 28767224]
  • Ashish Khaparde, Vijayalakshmi M A, Kishore K R Tetala. Development of a metal/chelate polyhydroxyethylmethacrylate monolith capillary for selective depletion of immunoglobulin G from human plasma for proteomics. Journal of chromatography. A. 2017 Sep; 1517(?):117-125. doi: 10.1016/j.chroma.2017.08.047. [PMID: 28859889]
  • Karan Karkra, Kishore K R Tetala, M A Vijayalakshmi. A structure based plasma protein pre-fractionation using conjoint immobilized metal/chelate affinity (IMA) system. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 May; 1052(?):1-9. doi: 10.1016/j.jchromb.2017.02.032. [PMID: 28343106]
  • Nianrong Sun, Jiawen Wang, Jizong Yao, Chunhui Deng. Hydrophilic Mesoporous Silica Materials for Highly Specific Enrichment of N-Linked Glycopeptide. Analytical chemistry. 2017 02; 89(3):1764-1771. doi: 10.1021/acs.analchem.6b04054. [PMID: 28068756]
  • Qing Zhang, Haoyu Zhao, Dong Li, Liping Liu, Shuhu Du. A surface-grafted ligand functionalization strategy for coordinate binding of doxorubicin at surface of PEGylated mesoporous silica nanoparticles: Toward pH-responsive drug delivery. Colloids and surfaces. B, Biointerfaces. 2017 Jan; 149(?):138-145. doi: 10.1016/j.colsurfb.2016.10.018. [PMID: 27750088]
  • Qing Zhang, Qing Zhang, Yanxing Guan, Shaozheng Liu, Qingjie Chen, Xiangmin Li. Synthesis and Biological Evaluation of a New Nitroimidazole-99mTc-Complex for Imaging of Hypoxia in Mice Model. Medical science monitor : international medical journal of experimental and clinical research. 2016 Oct; 22(?):3778-3791. doi: 10.12659/msm.898659. [PMID: 27752036]
  • Zhuangsheng Lin, Maxine J Roman, Eric A Decker, Julie M Goddard. Synthesis of Iminodiacetate Functionalized Polypropylene Films and Their Efficacy as Antioxidant Active-Packaging Materials. Journal of agricultural and food chemistry. 2016 Jun; 64(22):4606-17. doi: 10.1021/acs.jafc.6b01128. [PMID: 27243793]
  • Maofang He, Chaozhan Wang, Yinmao Wei. Selective enrichment and determination of monoamine neurotransmitters by CU(II) immobilized magnetic solid phase extraction coupled with high-performance liquid chromatography-fluorescence detection. Talanta. 2016 Jan; 147(?):437-44. doi: 10.1016/j.talanta.2015.10.017. [PMID: 26592630]
  • Magdalena Markowicz-Piasecka, Elżbieta Mikiciuk-Olasik, Joanna Sikora. Stability of erythrocyte membrane and overall hemostasis potential - A biocompatibility study of mebrofenin and other iminodiacetic acid derivatives. Pharmacological reports : PR. 2015 Dec; 67(6):1230-9. doi: 10.1016/j.pharep.2015.05.021. [PMID: 26481547]
  • Z Wei, S Sandron, A T Townsend, P N Nesterenko, B Paull. Determination of trace labile copper in environmental waters by magnetic nanoparticle solid phase extraction and high-performance chelation ion chromatography. Talanta. 2015 Apr; 135(?):155-62. doi: 10.1016/j.talanta.2014.12.048. [PMID: 25640140]
  • Hiroaki Matsumiya, Hiroto Inoue, Masataka Hiraide. Separation of Gd-humic complexes and Gd-based magnetic resonance imaging contrast agent in river water with QAE-Sephadex A-25 for the fractionation analysis. Talanta. 2014 Oct; 128(?):500-4. doi: 10.1016/j.talanta.2014.06.005. [PMID: 25059192]
  • Shasha Yao, Yanqin Huang, Yanbao Zhao, Yu Zhang, Xueyan Zou, Chunpeng Song. Iminodiacetic acid functionalized porous hydroxyapatite nanoparticles for capturing histidine-tagged proteins. Materials science & engineering. C, Materials for biological applications. 2014 Jun; 39(?):1-5. doi: 10.1016/j.msec.2014.02.034. [PMID: 24863189]
  • Andreas Kreuzeder, Jakob Santner, Thomas Prohaska, Walter W Wenzel. Gel for simultaneous chemical imaging of anionic and cationic solutes using diffusive gradients in thin films. Analytical chemistry. 2013 Dec; 85(24):12028-36. doi: 10.1021/ac403050f. [PMID: 24256092]
  • Jeanette E O'Sullivan, Roslyn J Watson, Edward C V Butler. An ICP-MS procedure to determine Cd, Co, Cu, Ni, Pb and Zn in oceanic waters using in-line flow-injection with solid-phase extraction for preconcentration. Talanta. 2013 Oct; 115(?):999-1010. doi: 10.1016/j.talanta.2013.06.054. [PMID: 24054694]
  • M Najam-ul-Haq, M Rainer, C W Huck, M N Ashiq, G K Bonn. Chemically modified diamond-like carbon (DLC) for protein enrichment and profiling by MALDI-MS. Amino acids. 2012 Aug; 43(2):823-31. doi: 10.1007/s00726-011-1138-1. [PMID: 22080208]
  • Marc Siegert, Heidi Pertl-Obermeyer, Gabriele Gadermaier, Fatima Ferreira, Gerhard Obermeyer. Expression of the major mugwort pollen allergen Art v 1 in tobacco plants and cell cultures: problems and perspectives for allergen production in plants. Plant cell reports. 2012 Mar; 31(3):561-71. doi: 10.1007/s00299-011-1199-3. [PMID: 22159963]
  • Chyi-Huey Josh Yeh, Ziad O Dimachkie, Avantika Golas, Alice Cheng, Purnendu Parhi, Erwin A Vogler. Contact activation of blood plasma and factor XII by ion-exchange resins. Biomaterials. 2012 Jan; 33(1):9-19. doi: 10.1016/j.biomaterials.2011.09.034. [PMID: 21982294]
  • Mohini Bhadwal, Drishty Satpati, Sweety Singhal, Haladhar Dev Sarma, Meera Venkatesh, Sharmila Banerjee. Preparation of 99mTc(CO)3-Carboxymethylthioethyl iminodiacetic acid and evaluation as a potential renal imaging agent. Current radiopharmaceuticals. 2012 Jan; 5(1):65-70. doi: 10.2174/1874471011205010065. [PMID: 21864246]
  • Shigeki Akamatsu, Naoki Yoshioka, Takao Mitsuhashi. Sensitive determination of cadmium in brown rice and spinach by flame atomic absorption spectrometry with solid-phase extraction. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2012; 29(11):1696-700. doi: 10.1080/19440049.2012.706835. [PMID: 22849394]
  • Zeina Mehyou, Ryszard Lobinski, Agnès Hagège. One-step coating of silica capillaries for selective protein retention by Cu(II)-IDA IMAC. Talanta. 2011 Dec; 87(?):168-73. doi: 10.1016/j.talanta.2011.09.057. [PMID: 22099664]
  • Beibei Chen, Bin Hu, Ping Jiang, Man He, Hanyong Peng, Xing Zhang. Nanoparticle labelling-based magnetic immunoassay on chip combined with electrothermal vaporization-inductively coupled plasma mass spectrometry for the determination of carcinoembryonic antigen in human serum. The Analyst. 2011 Oct; 136(19):3934-42. doi: 10.1039/c1an15387k. [PMID: 21858374]
  • Sing Teang Kong, Hai-Shu Lin, Jianhong Ching, Paul C Ho. Evaluation of dried blood spots as sample matrix for gas chromatography/mass spectrometry based metabolomic profiling. Analytical chemistry. 2011 Jun; 83(11):4314-8. doi: 10.1021/ac200662s. [PMID: 21520969]
  • Junfeng Ma, Chunyan Hou, Yu Liang, Tingting Wang, Zhen Liang, Lihua Zhang, Yukui Zhang. Efficient proteolysis using a regenerable metal-ion chelate immobilized enzyme reactor supported on organic-inorganic hybrid silica monolith. Proteomics. 2011 Mar; 11(5):991-5. doi: 10.1002/pmic.201000550. [PMID: 21280225]
  • Junping Wang, Xiaoxing Ma, Guozhen Fang, Mingfei Pan, Xiaoke Ye, Shuo Wang. Preparation of iminodiacetic acid functionalized multi-walled carbon nanotubes and its application as sorbent for separation and preconcentration of heavy metal ions. Journal of hazardous materials. 2011 Feb; 186(2-3):1985-92. doi: 10.1016/j.jhazmat.2010.12.087. [PMID: 21242030]
  • Jeanne C Stachowiak, Carl C Hayden, Mari Angelica A Sanchez, Julia Wang, Bruce C Bunker, James A Voigt, Darryl Y Sasaki. Targeting proteins to liquid-ordered domains in lipid membranes. Langmuir : the ACS journal of surfaces and colloids. 2011 Feb; 27(4):1457-62. doi: 10.1021/la1041458. [PMID: 21155607]
  • Min Zhang, Xiwen He, Langxing Chen, Yukui Zhang. Preparation and characterization of iminodiacetic acid-functionalized magnetic nanoparticles and its selective removal of bovine hemoglobin. Nanotechnology. 2011 Feb; 22(6):065705. doi: 10.1088/0957-4484/22/6/065705. [PMID: 21212492]
  • Jesús Muñoz-Bertomeu, María Angeles Bermúdez, Juan Segura, Roc Ros. Arabidopsis plants deficient in plastidial glyceraldehyde-3-phosphate dehydrogenase show alterations in abscisic acid (ABA) signal transduction: interaction between ABA and primary metabolism. Journal of experimental botany. 2011 Jan; 62(3):1229-39. doi: 10.1093/jxb/erq353. [PMID: 21068209]
  • P Subramaniam, A Knisely, B Portmann, S A Qureshi, W A Aclimandos, J B Karani, A J Baker. Diagnosis of Alagille syndrome-25 years of experience at King's College Hospital. Journal of pediatric gastroenterology and nutrition. 2011 Jan; 52(1):84-9. doi: 10.1097/mpg.0b013e3181f1572d. [PMID: 21119543]
  • Dolores Pérez, Sara Martín, Gloria Fernández-Lorente, Marco Filice, José Manuel Guisán, Antonio Ventosa, María Teresa García, Encarnación Mellado. A novel halophilic lipase, LipBL, showing high efficiency in the production of eicosapentaenoic acid (EPA). PloS one. 2011; 6(8):e23325. doi: 10.1371/journal.pone.0023325. [PMID: 21853111]
  • S M Abdel Azeem, W A A Arafa, M F el-Shahat. Synthesis and application of alizarin complexone functionalized polyurethane foam: preconcentration/separation of metal ions from tap water and human urine. Journal of hazardous materials. 2010 Oct; 182(1-3):286-94. doi: 10.1016/j.jhazmat.2010.06.028. [PMID: 20619967]
  • Homayon Ahmad Panahi, Jalil Morshedian, Nasrin Mehmandost, Elham Moniri, Igor Yu Galaev. Grafting of poly[1-(N,N-bis-carboxymethyl)amino-3-allylglycerol-co-dimethylacrylamide] copolymer onto siliceous support for preconcentration and determination of lead (II) in human plasma and environmental samples. Journal of chromatography. A. 2010 Aug; 1217(32):5165-72. doi: 10.1016/j.chroma.2010.06.012. [PMID: 20599201]
  • Dwinna Rahmi, Yuka Takasaki, Yanbei Zhu, Hiroharu Kobayashi, Shigeji Konagaya, Hiroki Haraguchi, Tomonari Umemura. Preparation of monolithic chelating adsorbent inside a syringe filter tip for solid phase microextraction of trace elements in natural water prior to their determination by ICP-MS. Talanta. 2010 Jun; 81(4-5):1438-45. doi: 10.1016/j.talanta.2010.02.048. [PMID: 20441920]
  • Sarah E Nilson, Sarah M Assmann. The alpha-subunit of the Arabidopsis heterotrimeric G protein, GPA1, is a regulator of transpiration efficiency. Plant physiology. 2010 Apr; 152(4):2067-77. doi: 10.1104/pp.109.148262. [PMID: 20200073]
  • Lars Opitz, Jonas Hohlweg, Udo Reichl, Michael W Wolff. Purification of cell culture-derived influenza virus A/Puerto Rico/8/34 by membrane-based immobilized metal affinity chromatography. Journal of virological methods. 2009 Nov; 161(2):312-6. doi: 10.1016/j.jviromet.2009.06.025. [PMID: 19591872]
  • Evgeny Kanshin, Shupei Wang, Lyudmila Ashmarina, Michael Fedjaev, Ilya Nifant'ev, Grant A Mitchell, Alexey V Pshezhetsky. The stoichiometry of protein phosphorylation in adipocyte lipid droplets: analysis by N-terminal isotope tagging and enzymatic dephosphorylation. Proteomics. 2009 Nov; 9(22):5067-77. doi: 10.1002/pmic.200800861. [PMID: 19921680]
  • Petra Sázelová, Václav Kasicka, Elena Ibáñez, Alejandro Cifuentes. Extraction and separation of water-soluble proteins from Bacillus thuringiensis-transgenic and non-transgenic maize species by CZE. Journal of separation science. 2009 Nov; 32(21):3801-8. doi: 10.1002/jssc.200900448. [PMID: 19813231]
  • Yazen Jmeian, Ziad El Rassi. Multicolumn separation platform for simultaneous depletion and prefractionation prior to 2-DE for facilitating in-depth serum proteomics profiling. Journal of proteome research. 2009 Oct; 8(10):4592-603. doi: 10.1021/pr900399q. [PMID: 19670910]
  • Shigeki Watanabe, Satoshi Watanabe, Jixin Liang, Hirofumi Hanaoka, Keigo Endo, Noriko S Ishioka. Chelating ion-exchange methods for the preparation of no-carrier-added 64Cu. Nuclear medicine and biology. 2009 Aug; 36(6):587-90. doi: 10.1016/j.nucmedbio.2009.04.005. [PMID: 19647164]
  • Carl C Hayden, Jane S Hwang, Elisa A Abate, Michael S Kent, Darryl Y Sasaki. Directed formation of lipid membrane microdomains as high affinity sites for His-tagged proteins. Journal of the American Chemical Society. 2009 Jul; 131(25):8728-9. doi: 10.1021/ja901157c. [PMID: 19505102]
  • Shun Feng, Na Yang, Subramaniam Pennathur, Steve Goodison, David M Lubman. Enrichment of glycoproteins using nanoscale chelating concanavalin A monolithic capillary chromatography. Analytical chemistry. 2009 May; 81(10):3776-83. doi: 10.1021/ac900085k. [PMID: 19366252]
  • R Tzoneva, B Seifert, W Albrecht, K Richau, T Groth, A Lendlein. Hemocompatibility of poly(ether imide) membranes functionalized with carboxylic groups. Journal of materials science. Materials in medicine. 2008 Oct; 19(10):3203-10. doi: 10.1007/s10856-008-3456-8. [PMID: 18452029]
  • Masahiro Takeyama, Keiji Nogami, Masahiro Okuda, Yoshihiko Sakurai, Tomoko Matsumoto, Ichiro Tanaka, Akira Yoshioka, Midori Shima. Selective factor VIII and V inactivation by iminodiacetate ion exchange resin through metal ion adsorption. British journal of haematology. 2008 Sep; 142(6):962-70. doi: 10.1111/j.1365-2141.2008.07289.x. [PMID: 18643923]
  • Shu-Hui Chen, Jue-Liang Hsu, Fong-Sian Lin. Fluorescein as a versatile tag for enhanced selectivity in analyzing cysteine-containing proteins/peptides using mass spectrometry. Analytical chemistry. 2008 Jul; 80(13):5251-9. doi: 10.1021/ac800436j. [PMID: 18512949]
  • M S Kent, H Yim, J K Murton, D Y Sasaki, B D Polizzotti, M B Charati, K L Kiick, I Kuzmenko, S Satija. Synthetic polypeptide adsorption to Cu-IDA containing lipid films: a model for protein-membrane interactions. Langmuir : the ACS journal of surfaces and colloids. 2008 Feb; 24(3):932-42. doi: 10.1021/la700940x. [PMID: 18179259]
  • Mariana Borsoi Ribeiro, Mookambesvaran Vijayalakshmi, Daniele Todorova-Balvay, Sonia Maria Alves Bueno. Effect of IDA and TREN chelating agents and buffer systems on the purification of human IgG with immobilized nickel affinity membranes. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2008 Jan; 861(1):64-73. doi: 10.1016/j.jchromb.2007.11.018. [PMID: 18068557]
  • Wassana Yantasee, Yuehe Lin, Kitiya Hongsirikarn, Glen E Fryxell, Raymond Addleman, Charles Timchalk. Electrochemical sensors for the detection of lead and other toxic heavy metals: the next generation of personal exposure biomonitors. Environmental health perspectives. 2007 Dec; 115(12):1683-90. doi: 10.1289/ehp.10190. [PMID: 18087583]
  • Shun Feng, Mingliang Ye, Houjiang Zhou, Xiaogang Jiang, Xingning Jiang, Hanfa Zou, Bolin Gong. Immobilized zirconium ion affinity chromatography for specific enrichment of phosphopeptides in phosphoproteome analysis. Molecular & cellular proteomics : MCP. 2007 Sep; 6(9):1656-65. doi: 10.1074/mcp.t600071-mcp200. [PMID: 17575324]
  • Chaozhan Wang, Lili Wang, Xindu Geng. [Refolding and purification of recombinant human granulocyte colony-stimulating factor from Escherichia coli by using protein folding liquid chromatography]. Se pu = Chinese journal of chromatography. 2007 Jul; 25(4):514-7. doi: 10.1016/s1872-2059(07)60020-0. [PMID: 17970109]
  • Yan Li, Xiuqing Xu, Bo Yan, Chunhui Deng, Wenjia Yu, Pengyuan Yang, Xiangmin Zhang. Microchip reactor packed with metal-ion chelated magnetic silica microspheres for highly efficient proteolysis. Journal of proteome research. 2007 Jun; 6(6):2367-75. doi: 10.1021/pr060558r. [PMID: 17477555]
  • Dwinna Rahmi, Yanbei Zhu, Eiji Fujimori, Tomonari Umemura, Hiroki Haraguchi. Multielement determination of trace metals in seawater by ICP-MS with aid of down-sized chelating resin-packed minicolumn for preconcentration. Talanta. 2007 Apr; 72(2):600-6. doi: 10.1016/j.talanta.2006.11.023. [PMID: 19071661]
  • Young-Eun Cho, Ria-Ann R Lomeda, Sang-Hoon Ryu, Jong-Hwa Lee, John H Beattie, In-Sook Kwun. Cellular Zn depletion by metal ion chelators (TPEN, DTPA and chelex resin) and its application to osteoblastic MC3T3-E1 cells. Nutrition research and practice. 2007; 1(1):29-35. doi: 10.4162/nrp.2007.1.1.29. [PMID: 20535382]
  • Matthias Rainer, Muhammad Najam-ul-Haq, Rania Bakry, Christian W Huck, Günther K Bonn. Mass spectrometric identification of serum peptides employing derivatized poly(glycidyl methacrylate/divinyl benzene) particles and mu-HPLC. Journal of proteome research. 2007 Jan; 6(1):382-6. doi: 10.1021/pr060426y. [PMID: 17203982]
  • Yan Li, Bo Yan, Xiuqing Xu, Chunhui Deng, Pengyuan Yang, Xizhong Shen, Xiangmin Zhang. On-column tryptic mapping of proteins using metal-ion-chelated magnetic silica microspheres by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid communications in mass spectrometry : RCM. 2007; 21(14):2263-8. doi: 10.1002/rcm.3073. [PMID: 17577873]
  • Ryuichiro Mizuno, Teruyuki Kawabata, Yuichi Sutoh, Yuzo Nishida, Shigeru Okada. Oxidative renal tubular injuries induced by aminocarboxylate-type iron (III) coordination compounds as candidate renal carcinogens. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2006 Dec; 19(6):675-83. doi: 10.1007/s10534-006-9004-4. [PMID: 16670936]
  • Takashi Sumida, Tetsuya Nakazato, Hiroaki Tao, Mitsuko Oshima, Shoji Motomizu. On-line preconcentration system using mini-column packed with a chelating resin for the characterization of seasonal variations of trace elements in seawater by ICP-MS and ICP-AES. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2006 Sep; 22(9):1163-8. doi: 10.2116/analsci.22.1163. [PMID: 16966803]
  • Isabel Feuerstein, Muhammad Najam-ul-Haq, Matthias Rainer, Lukas Trojer, Rania Bakry, Nurul Hidayat Aprilita, Günther Stecher, Christian W Huck, Günther K Bonn, Helmut Klocker, Georg Bartsch, Andras Guttman. Material-enhanced laser desorption/ionization (MELDI)--a new protein profiling tool utilizing specific carrier materials for time of flight mass spectrometric analysis. Journal of the American Society for Mass Spectrometry. 2006 Sep; 17(9):1203-8. doi: 10.1016/j.jasms.2006.04.032. [PMID: 16769219]
  • Chien-Chi Lin, Andrew T Metters. Enhanced protein delivery from photopolymerized hydrogels using a pseudospecific metal chelating ligand. Pharmaceutical research. 2006 Mar; 23(3):614-22. doi: 10.1007/s11095-005-9395-x. [PMID: 16397740]
  • Ashok Kumar, Vibha Bansal, Jonatan Andersson, Pradip K Roychoudhury, Bo Mattiasson. Supermacroporous cryogel matrix for integrated protein isolation. Immobilized metal affinity chromatographic purification of urokinase from cell culture broth of a human kidney cell line. Journal of chromatography. A. 2006 Jan; 1103(1):35-42. doi: 10.1016/j.chroma.2005.08.094. [PMID: 16368104]
  • Matthias Rainer, Najam-ul-Haq Muhammad, Christian W Huck, Isabel Feuerstein, Rania Bakry, Lukas A Huber, Douglas T Gjerde, Xiajuan Zou, Honggang Qian, Xiaojuan Du, Fang Wei-Gang, Yang Ke, Günther K Bonn. Ultra-fast mass fingerprinting by high-affinity capture of peptides and proteins on derivatized poly(glycidyl methacrylate/divinylbenzene) for the analysis of serum and cell lysates. Rapid communications in mass spectrometry : RCM. 2006; 20(19):2954-60. doi: 10.1002/rcm.2673. [PMID: 16953521]
  • Takashi Sumida, Tamami Ikenoue, Kazuhide Hamada, Akhmad Sabarudin, Mitsuko Oshima, Shoji Motomizu. On-line preconcentration using dual mini-columns for the speciation of chromium(III) and chromium(VI) and its application to water samples as studied by inductively coupled plasma-atomic emission spectrometry. Talanta. 2005 Dec; 68(2):388-93. doi: 10.1016/j.talanta.2005.08.064. [PMID: 18970334]
  • Isabel Feuerstein, Matthias Rainer, Katussevani Bernardo, Günther Stecher, Christian W Huck, Kurt Kofler, Alexandre Pelzer, Wolfgang Horninger, Helmut Klocker, Georg Bartsch, Günther K Bonn. Derivatized cellulose combined with MALDI-TOF MS: a new tool for serum protein profiling. Journal of proteome research. 2005 Nov; 4(6):2320-6. doi: 10.1021/pr050227z. [PMID: 16335981]
  • Nurul H Aprilita, Christian W Huck, Rania Bakry, Isabel Feuerstein, Guenther Stecher, Sandra Morandell, Hong-Lei Huang, Taras Stasyk, Lukas A Huber, Guenther K Bonn. Poly(glycidyl methacrylate/divinylbenzene)-IDA-FeIII in phosphoproteomics. Journal of proteome research. 2005 Nov; 4(6):2312-9. doi: 10.1021/pr050224m. [PMID: 16335980]
  • Angela R Piergiovanni, Giovanni Taranto. Simple and rapid method for the differentiation of Lens culinaris Medik. from false lentil species. Journal of agricultural and food chemistry. 2005 Aug; 53(17):6593-7. doi: 10.1021/jf0505426. [PMID: 16104771]
  • M S Kent, H Yim, D Y Sasaki, Sushil Satija, Young-Soo Seo, J Majewski. Adsorption of myoglobin to Cu(II)-IDA and Ni(II)-IDA functionalized langmuir monolayers: study of the protein layer structure during the adsorption process by neutron and X-ray reflectivity. Langmuir : the ACS journal of surfaces and colloids. 2005 Jul; 21(15):6815-24. doi: 10.1021/la047433q. [PMID: 16008391]
  • L Trojer, G Stecher, I Feuerstein, G K Bonn. Cu(II)-loaded iminodiacetic acid-silica particles for protein profiling of human serum samples using surface-enhanced affinity capture: support porosity effects. Rapid communications in mass spectrometry : RCM. 2005; 19(22):3398-404. doi: 10.1002/rcm.2205. [PMID: 16259043]
  • Payman Hashemi, Jafar Boroumand, Mohammad Reza Fat'hi. A dual column system using agarose-based adsorbents for preconcentration and speciation of chromium in water. Talanta. 2004 Oct; 64(3):578-83. doi: 10.1016/j.talanta.2004.03.035. [PMID: 18969644]
  • Electra Gizeli, Johanna Glad. Single-step formation of a biorecognition layer for assaying histidine-tagged proteins. Analytical chemistry. 2004 Jul; 76(14):3995-4001. doi: 10.1021/ac034855g. [PMID: 15253634]
  • Kazuhiko Tsukagoshi, Yasushi Shimadzu, Tatsuhiko Yamane, Riichiro Nakajima. Preparation of an iminodiacetic acid-modified capillary and its performance in capillary liquid chromatography and immobilized metal chelate affinity capillary electrophoresis. Journal of chromatography. A. 2004 Jun; 1040(1):151-4. doi: 10.1016/j.chroma.2004.03.063. [PMID: 15248436]
  • David B Senn, Sarah B Griscom, Christopher G Lewis, Jennifer P Galvin, Martha W Chang, James P Shine. Equilibrium-based sampler for determining Cu2+ concentrations in aquatic ecosystems. Environmental science & technology. 2004 Jun; 38(12):3381-6. doi: 10.1021/es0353614. [PMID: 15260338]
  • M S Kent, H Yim, D Y Sasaki, S Satija, J Majewski, T Gog. Analysis of myoglobin adsorption to Cu(II)-IDA and Ni(II)-IDA functionalized Langmuir monolayers by grazing incidence neutron and X-ray techniques. Langmuir : the ACS journal of surfaces and colloids. 2004 Mar; 20(7):2819-29. doi: 10.1021/la036207y. [PMID: 15835159]
  • Bhawana Mohani, Farukh Arjmand. Template synthesis of Co(II), Ni(II) and Cu(II) complexes derived from oxamide ligand and the reactivity of Cu(II) complex towards human serum albumin. Bioinorganic chemistry and applications. 2004; ?(?):225-35. doi: 10.1155/s1565363304000147. [PMID: 18365078]
  • Christophe A Marquette, Agnès Degiuli, Loïc J Blum. Electrochemiluminescent biosensors array for the concomitant detection of choline, glucose, glutamate, lactate, lysine and urate. Biosensors & bioelectronics. 2003 Dec; 19(5):433-9. doi: 10.1016/s0956-5663(03)00225-2. [PMID: 14623467]
  • Seong-Ho Choi, Young-Mi Hwang, Jae Jeong Ryoo, Kwang-Pill Lee, Kazutoku Ohta, Toyohide Takeuchi, Ji-Ye Jin, Chuzo Fujimoto. Surface grafting of glycidyl methacrylate on silica gel and polyethylene beads. Electrophoresis. 2003 Sep; 24(18):3181-6. doi: 10.1002/elps.200305581. [PMID: 14518042]
  • F Gode, E Pehlivan. A comparative study of two chelating ion-exchange resins for the removal of chromium(III) from aqueous solution. Journal of hazardous materials. 2003 Jun; 100(1-3):231-43. doi: 10.1016/s0304-3894(03)00110-9. [PMID: 12835025]
  • Chun-Yi Wu, Shing-Yi Suen, Shiow-Ching Chen, Jau-Hwan Tzeng. Analysis of protein adsorption on regenerated cellulose-based immobilized copper ion affinity membranes. Journal of chromatography. A. 2003 May; 996(1-2):53-70. doi: 10.1016/s0021-9673(03)00531-4. [PMID: 12830908]
  • Shizuko Hirata, Tasuku Kajiya, Masato Aihara, Kazuto Honda, Osamu Shikino. Determination of rare earth elements in seawater by on-line column preconcentration inductively coupled plasma mass spectrometry. Talanta. 2002 Dec; 58(6):1185-94. doi: 10.1016/s0039-9140(02)00418-6. [PMID: 18968856]
  • Yunhua Gao, Koji Oshita, Kyue-Hyung Lee, Mitsuko Oshima, Shoji Motomizu. Development of column-pretreatment chelating resins for matrix elimination/multi-element determination by inductively coupled plasma-mass spectrometry. The Analyst. 2002 Dec; 127(12):1713-9. doi: 10.1039/b208341h. [PMID: 12537384]
  • Roger Schibli, Rolf Schwarzbach, Roger Alberto, Kirstin Ortner, Helmut Schmalle, Cécile Dumas, André Egli, P August Schubiger. Steps toward high specific activity labeling of biomolecules for therapeutic application: preparation of precursor [(188)Re(H(2)O)(3)(CO)(3)](+) and synthesis of tailor-made bifunctional ligand systems. Bioconjugate chemistry. 2002 Jul; 13(4):750-6. doi: 10.1021/bc015568r. [PMID: 12121130]
  • Sabine A Lauer, John P Nolan. Development and characterization of Ni-NTA-bearing microspheres. Cytometry. 2002 Jul; 48(3):136-45. doi: 10.1002/cyto.10124. [PMID: 12116359]
  • Kyue-Hyung Lee, Mitsuko Oshima, Shoji Motomizu. Inductively coupled plasma mass spectrometric determination of heavy metals in sea-water samples after pre-treatment with a chelating resin disk by an on-line flow injection method. The Analyst. 2002 Jun; 127(6):769-74. doi: 10.1039/b201210n. [PMID: 12146909]
  • Q Luo, H Zou, X Xiao, Z Guo, L Kong, X Mao. Chromatographic separation of proteins on metal immobilized iminodiacetic acid-bound molded monolithic rods of macroporous poly(glycidyl methacrylate-co-ethylene dimethacrylate). Journal of chromatography. A. 2001 Aug; 926(2):255-64. doi: 10.1016/s0021-9673(01)01055-x. [PMID: 11556331]
  • S W Jeong, D F O'Brien. Synthesis of a polymerizable metal-ion-chelating lipid for fluid bilayers. The Journal of organic chemistry. 2001 Jul; 66(14):4799-802. doi: 10.1021/jo0100796. [PMID: 11442407]
  • R T Herrin, A W Andren, M M Shafer, D E Armstrong. Determination of silver speciation in natural waters. 2. Binding strength of silver ligands in surface freshwaters. Environmental science & technology. 2001 May; 35(10):1959-66. doi: 10.1021/es001510w. [PMID: 11393974]
  • J Petrig, R Schibli, C Dumas, R Alberto, P A Schubiger. Derivatization of glucose and 2-deoxyglucose for transition metal complexation: substitution reactions with organometallic 99mTc and Re precursors and fundamental NMR investigations. Chemistry (Weinheim an der Bergstrasse, Germany). 2001 May; 7(9):1868-73. doi: 10.1002/1521-3765(20010504)7:9<1868::aid-chem1868>3.0.co;2-h. [PMID: 11405464]
  • A M Peters, M J Myers, S Mohammadtaghi, M Mubashar, R T Mathie. Bidirectional transport of iminodiacetic organic anion analogues between plasma and hepatocyte. European journal of nuclear medicine. 1998 Jul; 25(7):766-73. doi: 10.1007/s002590050281. [PMID: 9662600]
  • N Yabe, H Matsui. Effects of iron chelates on the transferrin-free culture of rat dermal fibroblasts through active oxygen generation. In vitro cellular & developmental biology. Animal. 1997 Jul; 33(7):527-35. doi: 10.1007/s11626-997-0095-1. [PMID: 9282313]
  • D W Pack, F H Arnold. Langmuir monolayer characterization of metal chelating lipids for protein targeting to membranes. Chemistry and physics of lipids. 1997 Apr; 86(2):135-52. doi: 10.1016/s0009-3084(97)02662-5. [PMID: 9179995]
  • A M Schmidt, H N Müller, A Skerra. A Zn(II)-binding site engineered into retinol-binding protein exhibits metal-ion specificity and allows highly efficient affinity purification with a newly designed metal ligand. Chemistry & biology. 1996 Aug; 3(8):645-53. doi: 10.1016/s1074-5521(96)90132-5. [PMID: 8807898]