Ergostane (BioDeep_00000012987)

   

Volatile Flavor Compounds natural product


代谢物信息卡片


MS000027337

化学式: C28H50 (386.39123)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)C(C)CCC(C)C1CCC2C1(CCC3C2CCC4C3(CCCC4)C)C
InChI: InChI=1S/C28H50/c1-19(2)20(3)10-11-21(4)24-14-15-25-23-13-12-22-9-7-8-17-27(22,5)26(23)16-18-28(24,25)6/h19-26H,7-18H2,1-6H3/t20-,21+,22?,23-,24+,25-,26-,27-,28+/m0/s1

描述信息

同义名列表

3 个代谢物同义名

Ergostane; MS000027337; Ergostane



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

7 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Liang-Liang Zhai, Ting-Ting Jiang, Rong Zhang, Jian-Nan Li, Yi-Jie Zhai, Qiang Zhang, Ding Li, Wen-Bo Han. Ergostane-type sterols and sesquiterpenes with anti-neuroinflammatory activity from a Nigrograna species associated with Clematis shensiensis. Phytochemistry. 2023 Jul; 211(?):113690. doi: 10.1016/j.phytochem.2023.113690. [PMID: 37150432]
  • Qingyun Ma, Shuangshuang Zhang, Li Yang, Qingyi Xie, Haofu Dai, Zhifang Yu, Youxing Zhao. Lanostane Triterpenoids and Ergostane Steroids from Ganoderma luteomarginatum and Their Cytotoxicity. Molecules (Basel, Switzerland). 2022 Oct; 27(20):. doi: 10.3390/molecules27206989. [PMID: 36296582]
  • Yu Liang, Lanqin Li, Yong Shen, Yuyi Zheng, Qin Li, Qingyi Tong, Qun Zhou, Xiao-Nian Li, Dongyan Li, Hucheng Zhu, Weiguang Sun, Chunmei Chen, Yonghui Zhang. Four undescribed ergostane-type steroids from Lasiodiplodia pseudotheobromae and their neuroprotective activity. Phytochemistry. 2022 Sep; 201(?):113248. doi: 10.1016/j.phytochem.2022.113248. [PMID: 35643122]
  • Shou-Bai Liu, Zheng Cui, Hui-Qin Chen, Hao Wang, Wen-Hua Dong, Cai-Hong Cai, Wen-Li Mei, Hao-Fu Dai. A new ergostane derivative from the leaves of Heynea trijuga Roxburgh. Natural product research. 2021 Oct; 35(20):3494-3499. doi: 10.1080/14786419.2020.1712383. [PMID: 31951483]
  • Bin Li, Yi Kuang, Yang Yi, Xue Qiao, Lei Liang, Min Ye. Chemical modifications of ergostane-type triterpenoids from Antrodia camphorata and their cytotoxic activities. Bioorganic & medicinal chemistry letters. 2021 07; 43(?):128066. doi: 10.1016/j.bmcl.2021.128066. [PMID: 33915258]
  • Li-Hua Su, Chang-An Geng, Tian-Ze Li, Xiao-Yan Huang, Yun-Bao Ma, Xue-Mei Zhang, Gang Wu, Zhu-Liang Yang, Ji-Jun Chen. Spiroseoflosterol, a Rearranged Ergostane-Steroid from the Fruiting Bodies of Butyriboletus roseoflavus. Journal of natural products. 2020 05; 83(5):1706-1710. doi: 10.1021/acs.jnatprod.9b01282. [PMID: 32323991]
  • Gervais Mouthé Happi, Steven Collins N Wouamba, Mohamed Ismail, Simeon Fogue Kouam, Marcel Frese, Bruno Ndjakou Lenta, Norbert Sewald. Ergostane-type steroids from the Cameroonian 'white tiama' Entandrophragma angolense. Steroids. 2020 04; 156(?):108584. doi: 10.1016/j.steroids.2020.108584. [PMID: 31982421]
  • Gui-Hua Tang, Na Lu, Wei Li, Min Wu, Yun-Yun Chen, Hai-Ying Zhang, Shao-Yun He. Mannosylxylarinolide, a new 3,4-seco-ergostane-type steroidal saponin featuring a β-d-mannose from the endophytic fungus Xylaria sp. Journal of Asian natural products research. 2020 Apr; 22(4):397-403. doi: 10.1080/10286020.2018.1563075. [PMID: 30693785]
  • Xiao-Yun Huang, Zhi-Ming Liu, Hui-Ping Shi, Jiang Hu, Dun-Xin Han. Ergostane steroids from the ethanol extract of Dysoxylum mollissimum. Journal of Asian natural products research. 2019 Feb; 21(2):103-108. doi: 10.1080/10286020.2017.1392513. [PMID: 29082753]
  • Yannick Fouokeng, Carine Mvot Akak, Michel Feussi Tala, Anatole Guy Blaise Azebaze, Birger Dittrich, Juliette Catherine Vardamides, Hartmut Laatsch. The structure of antrocarine E, an ergostane isolated from Antrocaryon klaineanum Pierre (Anacardiaceae). Fitoterapia. 2017 Mar; 117(?):61-64. doi: 10.1016/j.fitote.2017.01.002. [PMID: 28065698]
  • Pascal D Douanla, Turibio Kuiate Tabopda, Alembert T Tchinda, Ewa Cieckiewicz, Michel Frédérich, Fabrice Fekam Boyom, Nole Tsabang, Samuel Yeboah, Augustin E Nkengfack, Marguerite Hortence K Tchuendem. Antrocarines A-F, antiplasmodial ergostane steroids from the stem bark of Antrocaryon klaineanum. Phytochemistry. 2015 Sep; 117(?):521-526. doi: 10.1016/j.phytochem.2015.07.011. [PMID: 26232555]
  • Xue Qiao, Qi Wang, Shuai Ji, Yun Huang, Ke-di Liu, Zheng-xiang Zhang, Tao Bo, Yew-min Tzeng, De-an Guo, Min Ye. Metabolites identification and multi-component pharmacokinetics of ergostane and lanostane triterpenoids in the anticancer mushroom Antrodia cinnamomea. Journal of pharmaceutical and biomedical analysis. 2015; 111(?):266-76. doi: 10.1016/j.jpba.2015.04.010. [PMID: 25912848]
  • Hua Guo, Zheng-Hui Li, Tao Feng, Ji-Kai Liu. One new ergostane-type steroid and three new phthalide derivatives from cultures of the basidiomycete Albatrellus confluens. Journal of Asian natural products research. 2015; 17(2):107-13. doi: 10.1080/10286020.2014.951925. [PMID: 25465923]
  • Wei Xu, Fong-Fu Hsu, Eda Baykal, Juyang Huang, Kai Zhang. Sterol biosynthesis is required for heat resistance but not extracellular survival in leishmania. PLoS pathogens. 2014 Oct; 10(10):e1004427. doi: 10.1371/journal.ppat.1004427. [PMID: 25340392]
  • Abhinav Grover, Rumani Singh, Ashutosh Shandilya, Didik Priyandoko, Vibhuti Agrawal, Virendra S Bisaria, Renu Wadhwa, Sunil C Kaul, Durai Sundar. Ashwagandha derived withanone targets TPX2-Aurora A complex: computational and experimental evidence to its anticancer activity. PloS one. 2012; 7(1):e30890. doi: 10.1371/journal.pone.0030890. [PMID: 22303466]
  • Abhinav Grover, Ashutosh Shandilya, Ankita Punetha, Virendra S Bisaria, Durai Sundar. Inhibition of the NEMO/IKKβ association complex formation, a novel mechanism associated with the NF-κB activation suppression by Withania somnifera's key metabolite withaferin A. BMC genomics. 2010 Dec; 11 Suppl 4(?):S25. doi: 10.1186/1471-2164-11-s4-s25. [PMID: 21143809]
  • Abhinav Grover, Ashutosh Shandilya, Virendra S Bisaria, Durai Sundar. Probing the anticancer mechanism of prospective herbal drug Withaferin A on mammals: a case study on human and bovine proteasomes. BMC genomics. 2010 Dec; 11 Suppl 4(?):S15. doi: 10.1186/1471-2164-11-s4-s15. [PMID: 21143798]
  • Mohammad Hossein Mirjalili, Elisabeth Moyano, Mercedes Bonfill, Rosa M Cusido, Javier Palazón. Steroidal lactones from Withania somnifera, an ancient plant for novel medicine. Molecules (Basel, Switzerland). 2009 Jul; 14(7):2373-93. doi: 10.3390/molecules14072373. [PMID: 19633611]
  • Rajender Singh Sangwan, Narayan Das Chaurasiya, Payare Lal, Laxminarain Misra, Rakesh Tuli, Neelam Singh Sangwan. Withanolide A is inherently de novo biosynthesized in roots of the medicinal plant Ashwagandha (Withania somnifera). Physiologia plantarum. 2008 Jun; 133(2):278-87. doi: 10.1111/j.1399-3054.2008.01076.x. [PMID: 18312497]
  • Kulothungan Ganapathy, Christopher W Jones, Camille M Stephens, Rit Vatsyayan, Julie A Marshall, W David Nes. Molecular probing of the Saccharomyces cerevisiae sterol 24-C methyltransferase reveals multiple amino acid residues involved with C2-transfer activity. Biochimica et biophysica acta. 2008 Jun; 1781(6-7):344-51. doi: 10.1016/j.bbalip.2008.04.015. [PMID: 18503783]
  • Chien-Chang Shen, Yea-Hwey Wang, Tun-Tschu Chang, Lie-Chwen Lin, Ming-Jaw Don, Yu-Chang Hou, Kuo-Tong Liou, Shiou Chang, Wen-Yen Wang, Han-Chieh Ko, Yuh-Chiang Shen. Anti-inflammatory ergostanes from the basidiomata of Antrodia salmonea. Planta medica. 2007 Sep; 73(11):1208-13. doi: 10.1055/s-2007-981591. [PMID: 17764065]
  • Hui-Chiu Chang, Fang-Rong Chang, Yu-Chu Wang, Mei-Ren Pan, Wen-Chun Hung, Yang-Chang Wu. A bioactive withanolide Tubocapsanolide A inhibits proliferation of human lung cancer cells via repressing Skp2 expression. Molecular cancer therapeutics. 2007 May; 6(5):1572-8. doi: 10.1158/1535-7163.mct-06-0812. [PMID: 17513606]
  • A Berger, D Rein, E Kratky, I Monnard, H Hajjaj, I Meirim, C Piguet-Welsch, J Hauser, K Mace, P Niederberger. Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs. Lipids in health and disease. 2004 Feb; 3(?):2. doi: 10.1186/1476-511x-3-2. [PMID: 14969592]
  • W W Harding, H Jacobs, P A Lewis, S McLean, W F Reynolds. Cycloartanes, protolimonoids, a pregnane and a new ergostane from Trichilia reticulata. Natural product letters. 2001; 15(4):253-60. doi: 10.1080/10575630108041289. [PMID: 11833620]