3,5-DINITROTOLUENE (BioDeep_00000012827)

   


代谢物信息卡片


3,5-DINITROTOLUENE

化学式: C7H6N2O4 (182.0328)
中文名称: 3,5-二硝基甲苯
谱图信息: 最多检出来源 Homo sapiens(not specific) 50%

分子结构信息

SMILES: CC1=CC(=CC(=C1)[N+](=O)[O-])[N+](=O)[O-]
InChI: InChI=1S/C7H6N2O4/c1-5-2-6(8(10)11)4-7(3-5)9(12)13/h2-4H,1H3

描述信息

同义名列表

2 个代谢物同义名

3,5-DINITROTOLUENE; 3,5-Dinitrotoluene



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Youping Deng, Sharon A Meyer, Xin Guan, Barbara Lynn Escalon, Junmei Ai, Mitchell S Wilbanks, Ruth Welti, Natàlia Garcia-Reyero, Edward J Perkins. Analysis of common and specific mechanisms of liver function affected by nitrotoluene compounds. PloS one. 2011 Feb; 6(2):e14662. doi: 10.1371/journal.pone.0014662. [PMID: 21346803]
  • Norka E Paden, Ernest E Smith, Ronald J Kendall. Acute toxicity of 2,4,6-trinitrotoluene, 2,4-dinitrotoluene, and 2,6-dinitrotoluene in the adult bullfrog (Lithobates catesbeiana). Bulletin of environmental contamination and toxicology. 2008 Jun; 80(6):487-91. doi: 10.1007/s00128-008-9467-9. [PMID: 18551238]
  • Yu-Hong Su, Yong-Guan Zhu. Transport mechanisms for the uptake of organic compounds by rice (Oryza sativa) roots. Environmental pollution (Barking, Essex : 1987). 2007 Jul; 148(1):94-100. doi: 10.1016/j.envpol.2006.11.004. [PMID: 17240019]
  • Mark S Johnson, Mark W Michie, Matthew A Bazar, Robert M Gogal. Influence of oral 2,4-dinitrotoluene exposure to the northern bobwhite (Colinus virginianus). International journal of toxicology. 2005 Jul; 24(4):265-74. doi: 10.1080/10915810591007247. [PMID: 16126620]
  • Gian Gupta, Hemalatha Bhaskaran. Use of poultry litter for biodegradation of soil contaminated with 2,4- and 2,6-dinitrotoluene. Journal of hazardous materials. 2004 Dec; 116(1-2):167-71. doi: 10.1016/j.jhazmat.2004.09.007. [PMID: 15561375]
  • Ales Nepovím, Radka Podlipná, Petr Soudek, Peter Schröder, Tomás Vanek. Effects of heavy metals and nitroaromatic compounds on horseradish glutathione S-transferase and peroxidase. Chemosphere. 2004 Nov; 57(8):1007-15. doi: 10.1016/j.chemosphere.2004.08.030. [PMID: 15488591]
  • S Letzel, Th Göen, M Bader, J Angerer, T Kraus. Exposure to nitroaromatic explosives and health effects during disposal of military waste. Occupational and environmental medicine. 2003 Jul; 60(7):483-8. doi: 10.1136/oem.60.7.483. [PMID: 12819281]
  • Thomas Brüning, Ricarda Thier, Hermann M Bolt. Nephrotoxicity and nephrocarcinogenicity of dinitrotoluene: new aspects to be considered. Reviews on environmental health. 2002 Jul; 17(3):163-72. doi: 10.1515/reveh.2002.17.3.163. [PMID: 12462481]
  • C Zhang, R C Daprato, S F Nishino, J C Spain, J B Hughes. Remediation of dinitrotoluene contaminated soils from former ammunition plants: soil washing efficiency and effective process monitoring in bioslurry reactors. Journal of hazardous materials. 2001 Oct; 87(1-3):139-54. doi: 10.1016/s0304-3894(01)00240-0. [PMID: 11566406]
  • T Brüning, R Thier, H Mann, H Melzer, P Bröde, G Dallner, H M Bolt. Pathological excretion patterns of urinary proteins in miners highly exposed to dinitrotoluene. Journal of occupational and environmental medicine. 2001 Jul; 43(7):610-5. doi: 10.1097/00043764-200107000-00007. [PMID: 11464391]