1,3-Propane sultone (BioDeep_00000012739)

 

Secondary id: BioDeep_00001868079

human metabolite blood metabolite


代谢物信息卡片


1,2λ⁶-oxathiolane-2,2-dione

化学式: C3H6O3S (122.0037646)
中文名称: 1,3-丙磺酸内酯
谱图信息: 最多检出来源 Homo sapiens(blood) 95.35%

分子结构信息

SMILES: C1COS(=O)(=O)C1
InChI: InChI=1S/C3H6O3S/c4-7(5)3-1-2-6-7/h1-3H2

描述信息

同义名列表

5 个代谢物同义名

1,2λ⁶-oxathiolane-2,2-dione; 1,3-Propane sultone; 1,3-Propanesultone; Propane sultone; sultone



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Dong Yan Zhang, Shu Xiong, Yu Sheng Shi, Jun Zhu, Qiao Li Hu, Jie Liu, Yan Wang. Antifouling enhancement of polyimide membrane by grafting DEDA-PS zwitterions. Chemosphere. 2018 May; 198(?):30-39. doi: 10.1016/j.chemosphere.2018.01.120. [PMID: 29421743]
  • Rong Yang, Karen K Gleason. Ultrathin antifouling coatings with stable surface zwitterionic functionality by initiated chemical vapor deposition (iCVD). Langmuir : the ACS journal of surfaces and colloids. 2012 Aug; 28(33):12266-74. doi: 10.1021/la302059s. [PMID: 22873558]
  • Da Ma, Gaya Hettiarachchi, Duc Nguyen, Ben Zhang, James B Wittenberg, Peter Y Zavalij, Volker Briken, Lyle Isaacs. Acyclic cucurbit[n]uril molecular containers enhance the solubility and bioactivity of poorly soluble pharmaceuticals. Nature chemistry. 2012 Apr; 4(6):503-10. doi: 10.1038/nchem.1326. [PMID: 22614387]
  • Stephen D Dertinger, Souk Phonethepswath, Pamela Weller, Svetlana Avlasevich, Dorothea K Torous, Jared A Mereness, Steven M Bryce, Jeffrey C Bemis, Sara Bell, Susan Portugal, Michael Aylott, James T MacGregor. Interlaboratory Pig-a gene mutation assay trial: Studies of 1,3-propane sultone with immunomagnetic enrichment of mutant erythrocytes. Environmental and molecular mutagenesis. 2011 Dec; 52(9):748-55. doi: 10.1002/em.20671. [PMID: 22052433]
  • Chunfeng Ma, Hao Zhou, Bo Wu, Guangzhao Zhang. Preparation of polyurethane with zwitterionic side chains and their protein resistance. ACS applied materials & interfaces. 2011 Feb; 3(2):455-61. doi: 10.1021/am101039q. [PMID: 21222476]
  • Jiang Yuan, Sicong Lin, Jian Shen. Enhanced blood compatibility of polyurethane functionalized with sulfobetaine. Colloids and surfaces. B, Biointerfaces. 2008 Oct; 66(1):90-5. doi: 10.1016/j.colsurfb.2008.05.020. [PMID: 18620851]
  • Yuan Jiang, Hou Qingfeng, Liu Baolei, Shen Jian, Lin Sicong. Platelet adhesive resistance of polyurethane surface grafted with zwitterions of sulfobetaine. Colloids and surfaces. B, Biointerfaces. 2004 Jul; 36(1):19-26. doi: 10.1016/j.colsurfb.2004.03.016. [PMID: 15261019]
  • E Elmore, D E Stringer, V E Steele, E W Gerner, J L Redpath. Chemoprevention by difluoromethylornithine: correlation of an in vitro human cell assay with human clinical data for biomarker modulation. Anticancer research. 2001 Mar; 21(2A):1163-5. doi: NULL. [PMID: 11396157]
  • E Elmore, T T Luc, H R Li, J A Buckmeier, V E Steele, G J Kelloff, J L Redpath. Correlation of chemopreventive efficacy data from the human epidermal cell assay with in vivo data. Anticancer research. 2000 Jan; 20(1A):27-32. doi: NULL. [PMID: 10769631]
  • Z O Kubinski, H Kubinski. Alterations in Bacillus subtilis transforming DNA induced by beta-propiolactone and 1,3-propane sultone, two mutagenic and carcinogenic alkylating agents. Journal of bacteriology. 1978 Dec; 136(3):854-66. doi: 10.1128/jb.136.3.854-866.1978. [PMID: 102637]
  • U T Rüegg, J Rudinger. Reaction of cysteine thiol groups with 1,3-propane sultone: S-3-sulphopropyl as a modifying group for protein chemistry. International journal of peptide and protein research. 1974; 6(6):447-56. doi: 10.1111/j.1399-3011.1974.tb02405.x. [PMID: 4455639]