Zoxamide (BioDeep_00000012472)

   

natural product


代谢物信息卡片


Pesticide4_Zoxamide_C14H16Cl3NO2_3,5-Dichloro-N-(1-chloro-3-methyl-2-oxopentan-3-yl)-4-methylbenzamide

化学式: C14H16Cl3NO2 (335.0247)
中文名称: 苯酰菌胺
谱图信息: 最多检出来源 Escherichia coli(natural_products) 60%

分子结构信息

SMILES: CCC(C)(C(=O)CCl)NC(=O)C1=CC(=C(C(=C1)Cl)C)Cl
InChI: InChI=1S/C14H16Cl3NO2/c1-4-14(3,12(19)7-15)18-13(20)9-5-10(16)8(2)11(17)6-9/h5-6H,4,7H2,1-3H3,(H,18,20)

描述信息

同义名列表

3 个代谢物同义名

Zoxamide; Pesticide4_Zoxamide_C14H16Cl3NO2_3,5-Dichloro-N-(1-chloro-3-methyl-2-oxopentan-3-yl)-4-methylbenzamide; Zoxamide



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • M Andrés Velasco-Saavedra, Efrén Mar-Antonio, Rodrigo Aguayo-Ortiz. Molecular Insights into the Covalent Binding of Zoxamide to the β-Tubulin of Botrytis cinerea. Journal of chemical information and modeling. 2023 Oct; ?(?):. doi: 10.1021/acs.jcim.3c00911. [PMID: 37802126]
  • Hui Liu, Yue Wang, Xinyu Shi. Co-existing antibiotics alter the enantioselective dissipation characteristics of zoxamide and drive combined impact on soil microenvironment. Journal of environmental management. 2023 Jun; 344(?):118340. doi: 10.1016/j.jenvman.2023.118340. [PMID: 37336018]
  • Zhiping Che, Yibo Liu, Luyao Chen, Puhou Xing, Xiangdong Li, Xiaobo Huang, Shengming Liu, Genqiang Chen, Xiaomin Lin, Yuee Tian. Synthesis of Hinokitiol Sulfonate Derivatives and Their Anti-Oomycete and Nematicidal Activities. Chemistry & biodiversity. 2022 Sep; 19(9):e202200580. doi: 10.1002/cbdv.202200580. [PMID: 35975883]
  • Hui Liu, Mei Shan, Mengqi Liu, Jiaqi Song, Kuiyuan Chen. Assessment of the eco-toxicological effects in zoxamide polluted soil amended with fertilizers-An indoor evaluation. Chemosphere. 2022 Aug; 301(?):134630. doi: 10.1016/j.chemosphere.2022.134630. [PMID: 35447215]
  • Francesco Corrias, Anna Melis, Alessandro Atzei, Salvatore Marceddu, Fabrizio Dedola, Antonella Sirigu, Rosa Pireddu, Francesco Lai, Alberto Angioni. Zoxamide accumulation and retention evaluation after nanosuspension technology application in tomato plant. Pest management science. 2021 Jul; 77(7):3508-3518. doi: 10.1002/ps.6404. [PMID: 33837628]
  • Xinglu Pan, Xiaomao Wu, Na Liu, Jun Xu, Xingang Liu, Xiaohu Wu, Yueliang Feng, Runan Li, Fengshou Dong, Yongquan Zheng. A systematic evaluation of zoxamide at enantiomeric level. The Science of the total environment. 2020 Sep; 733(?):139069. doi: 10.1016/j.scitotenv.2020.139069. [PMID: 32446056]
  • Xinglu Pan, Fengshou Dong, Na Liu, Youpu Cheng, Jun Xu, Xingang Liu, Xiaohu Wu, Zenglong Chen, Yongquan Zheng. The fate and enantioselective behavior of zoxamide during wine-making process. Food chemistry. 2018 May; 248(?):14-20. doi: 10.1016/j.foodchem.2017.12.052. [PMID: 29329837]
  • Xinglu Pan, Fengshou Dong, Zenglong Chen, Jun Xu, Xingang Liu, Xiaohu Wu, Yongquan Zheng. The application of chiral ultra-high-performance liquid chromatography tandem mass spectrometry to the separation of the zoxamide enantiomers and the study of enantioselective degradation process in agricultural plants. Journal of chromatography. A. 2017 Nov; 1525(?):87-95. doi: 10.1016/j.chroma.2017.10.016. [PMID: 29030041]
  • Meng Cai, Dong Lin, Lei Chen, Yang Bi, Lu Xiao, Xi-li Liu. M233I Mutation in the β-Tubulin of Botrytis cinerea Confers Resistance to Zoxamide. Scientific reports. 2015 Nov; 5(?):16881. doi: 10.1038/srep16881. [PMID: 26596626]
  • Xinyue Mei, Min Yang, Bingbing Jiang, Xupo Ding, Weiping Deng, Yumei Dong, Lei Chen, Xili Liu, Shusheng Zhu. Proteomic analysis on zoxamide-induced sensitivity changes in Phytophthora cactorum. Pesticide biochemistry and physiology. 2015 Sep; 123(?):9-18. doi: 10.1016/j.pestbp.2015.01.012. [PMID: 26267047]
  • Xinyue Mei, Min Yang, Xupo Ding, Yang Bi, Lei Chen, Weiping Deng, Yumei Dong, Yuan Su, Xiahong He, Shusheng Zhu, Xili Liu. Proteomic analysis of zoxamide-induced changes in Phytophthora cactorum. Pesticide biochemistry and physiology. 2014 Jul; 113(?):31-9. doi: 10.1016/j.pestbp.2014.06.004. [PMID: 25052524]
  • Lynda V Podhorniak. A rapid miniaturized residue analytical method for the determination of zoxamide and its two acid metabolites in ginseng roots using UPLC-MS/MS. Journal of agricultural and food chemistry. 2014 Apr; 62(17):3702-9. doi: 10.1021/jf405403v. [PMID: 24552297]
  • Yang Bi, Lei Chen, Meng Cai, Shusheng Zhu, Zhili Pang, Xili Liu. Two non-target recessive genes confer resistance to the anti-oomycete microtubule inhibitor zoxamide in Phytophthora capsici. PloS one. 2014; 9(2):e89336. doi: 10.1371/journal.pone.0089336. [PMID: 24586697]
  • Arnaud Tonnelier, Sandra Coecke, José-Manuel Zaldívar. Screening of chemicals for human bioaccumulative potential with a physiologically based toxicokinetic model. Archives of toxicology. 2012 Mar; 86(3):393-403. doi: 10.1007/s00204-011-0768-0. [PMID: 22089525]
  • Emil Rekanović, Ivana Potočnik, Svetlana Milijašević-Marčić, Miloš Stepanović, Biljana Todorović, Milica Mihajlović. Toxicity of metalaxyl, azoxystrobin, dimethomorph, cymoxanil, zoxamide and mancozeb to Phytophthora infestans isolates from Serbia. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2012; 47(5):403-9. doi: 10.1080/03601234.2012.657043. [PMID: 22424065]
  • Yang Bi, Xiaolan Cui, Xiaohong Lu, Meng Cai, Xili Liu, Jianjun J Hao. Baseline sensitivity of natural population and resistance of mutants in Phytophthora capsici to zoxamide. Phytopathology. 2011 Sep; 101(9):1104-11. doi: 10.1094/phyto-01-11-0010. [PMID: 21692644]
  • Xiao Hong Lu, Shu Sheng Zhu, Yang Bi, Xi Li Liu, Jianjun J Hao. Baseline sensitivity and resistance-risk assessment of Phytophthora capsici to iprovalicarb. Phytopathology. 2010 Nov; 100(11):1162-8. doi: 10.1094/phyto-12-09-0351. [PMID: 20932164]
  • F Oesch, M Metzler, E Fabian, H Kamp, T Bernshausen, G Damm, S Triebel, J Döhmer, R Landsiedel, B Van Ravenzwaay. In vitro mammalian metabolism of the mitosis inhibitor zoxamide and the relationship to its in vitro toxicity. Xenobiotica; the fate of foreign compounds in biological systems. 2010 Jan; 40(1):72-82. doi: 10.3109/00498250903353464. [PMID: 20001673]
  • M L Gullino, G Gilardi, A Garibaldi. Chemical control of downy mildew on lettuce and basil under greenhouse. Communications in agricultural and applied biological sciences. 2009; 74(3):933-40. doi: . [PMID: 20222581]
  • L La Pera, G Dugo, R Rando, G Di Bella, R Maisano, F Salvo. Statistical study of the influence of fungicide treatments (mancozeb, zoxamide and copper oxychloride) on heavy metal concentrations in Sicilian red wine. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2008 Mar; 25(3):302-13. doi: 10.1080/02652030701329603. [PMID: 18311621]
  • Carole Martinez, C André Lévesque, Richard R Bélanger, Russell J Tweddell. Evaluation of fungicides for the control of carrot cavity spot. Pest management science. 2005 Aug; 61(8):767-71. doi: 10.1002/ps.1055. [PMID: 15880371]
  • D H Young, S L Spiewak, R A Slawecki. Laboratory studies to assess the risk of development of resistance to zoxamide. Pest management science. 2001 Nov; 57(11):1081-7. doi: 10.1002/ps.399. [PMID: 11721527]