Metacetaldehyde (BioDeep_00000012403)

 

Secondary id: BioDeep_00001867898

human metabolite blood metabolite


代谢物信息卡片


2,4,6,8-tetramethyl-1,3,5,7-tetraoxocane

化学式: C8H16O4 (176.1049)
中文名称: 四聚乙醛, 金属醛
谱图信息: 最多检出来源 Homo sapiens(blood) 83.33%

分子结构信息

SMILES: CC1OC(C)OC(C)OC(C)O1
InChI: InChI=1S/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3

描述信息

D010575 - Pesticides > D008975 - Molluscacides
D016573 - Agrochemicals

同义名列表

5 个代谢物同义名

2,4,6,8-tetramethyl-1,3,5,7-tetraoxocane; Metacetaldehyde; METALDEHYDE; Metaldehyde; Metaldehyde



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Elham Farghal Elkady, Haytham A Ayoub, Amina M Ibrahim. Molluscicidal activity of calcium borate nanoparticles with kodom ball-flower structure on hematological, histological and biochemical parameters of Eobania vermiculata snails. Pesticide biochemistry and physiology. 2024 Jan; 198(?):105716. doi: 10.1016/j.pestbp.2023.105716. [PMID: 38225073]
  • Oksal Macar, Tuğçe Kalefetoğlu Macar, Kültiğin Çavuşoğlu, Emine Yalçın, Ali Acar. Assessing the combined toxic effects of metaldehyde mollucide. Scientific reports. 2023 03; 13(1):4888. doi: 10.1038/s41598-023-32183-6. [PMID: 36966255]
  • Oksal Macar, Tuğçe Kalefetoğlu Macar, Emine Yalçin, Kültiğin Çavuşoğlu, Ali Acar. Molecular docking and spectral shift supported toxicity profile of metaldehyde mollucide and the toxicity-reducing effects of bitter melon extract. Pesticide biochemistry and physiology. 2022 Oct; 187(?):105201. doi: 10.1016/j.pestbp.2022.105201. [PMID: 36127072]
  • Yasser Abobakr, Amira F Gad, Hamza S Abou-Elnasr, Gaber M Abdelgalil, Hamdy I Hussein, Shady Selim. Contact toxicity and biochemical impact of metaldehyde against the white garden snail Theba pisana (Müller, 1774). Pest management science. 2021 Jul; 77(7):3208-3215. doi: 10.1002/ps.6359. [PMID: 33683007]
  • Ana Flávia Machado Botelho, Amanda Milhomem Donato Machado, Rayanne Henrique Santana da Silva, Amanda Carvalho Faria, Lucas Santos Machado, Heloa Santos, Sandro de Melo Braga, Bruno Benetti Junta Torres, Marina Pacheco Miguel, Andrea Rodrigues Chaves, Marília Martins Melo. Fatal metaldehyde poisoning in a dog confirmed by gas chromatography. BMC veterinary research. 2020 May; 16(1):139. doi: 10.1186/s12917-020-02348-w. [PMID: 32414366]
  • Zhengyi Chen, Gongke Li, Zhuomin Zhang. Miniaturized array gas membrane separation strategy for rapid analysis of complex samples by surface-enhanced Raman scattering. Analytica chimica acta. 2019 Aug; 1065(?):29-39. doi: 10.1016/j.aca.2019.03.031. [PMID: 31005148]
  • Daniel Dörler, Agnes Scheucher, Johann G Zaller. Efficacy of chemical and biological slug control measures in response to watering and earthworms. Scientific reports. 2019 02; 9(1):2954. doi: 10.1038/s41598-019-39585-5. [PMID: 30814638]
  • Glenn D Castle, Graham A Mills, Anthony Gravell, Alister Leggatt, Jeff Stubbs, Richard Davis, Gary R Fones. Comparison of different monitoring methods for the measurement of metaldehyde in surface waters. Environmental monitoring and assessment. 2019 Jan; 191(2):75. doi: 10.1007/s10661-019-7221-x. [PMID: 30648204]
  • Elisabeth L Mauser, Birgit Puschner, Sven Reese, Katrin Hartmann, René Doerfelt. Evaluation of the in vitro efficacy of hemodialysis, hemoperfusion, and the combined approach on the removal of metaldehyde from canine plasma. Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001). 2016 Jul; 26(4):516-23. doi: 10.1111/vec.12487. [PMID: 27219514]
  • Han-cheng Liu, Cheng-hui Zhong, Chun-mei Xu, Xian-guo Liu, Hua-shan Sun, Xi-fu Huang, Zuo-jun Li, Chang-jun Liao, Jun-jing Yang, Jian-bing Liu, Hong-ping Fan. [Molluscicidal effect comparison between TDS and MNSC in field]. Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control. 2014 Jun; 26(3):265-9. doi: ". [PMID: 25345150]
  • Zhi-hai Zhang, Rong Fang, Bin Yu, Zhi-shuang Liu, Ze-jun Zhao, Xin-wen Xu, Xiu-long Huang, Tie-wu Jia. [Field evaluation of a novel plant molluscicide 'Luo-wei' against Oncomelania hupensis snails II molluscicidal effect in the field of lake areas in Hanchuan City, Hubei Province]. Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control. 2013 Oct; 25(5):481-4. doi: ". [PMID: 24490357]
  • David J Craik. Host-defense activities of cyclotides. Toxins. 2012 02; 4(2):139-56. doi: 10.3390/toxins4020139. [PMID: 22474571]
  • Lingpeng Dai, Wanxian Wang, Xinjiao Dong, Renyong Hu, Xuyang Nan. Molluscicidal activity of cardiac glycosides from Nerium indicum against Pomacea canaliculata and its implications for the mechanisms of toxicity. Environmental toxicology and pharmacology. 2011 Sep; 32(2):226-32. doi: 10.1016/j.etap.2011.05.007. [PMID: 21843803]
  • Matthew T Martin, Richard S Judson, David M Reif, Robert J Kavlock, David J Dix. Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef Database. Environmental health perspectives. 2009 Mar; 117(3):392-9. doi: 10.1289/ehp.0800074. [PMID: 19337514]
  • Takeshi Saito, Seiji Morita, Megumi Motojyuku, Kazuki Akieda, Hiroyuki Otsuka, Isotoshi Yamamoto, Sadaki Inokuchi. Determination of metaldehyde in human serum by headspace solid-phase microextraction and gas chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2008 Nov; 875(2):573-6. doi: 10.1016/j.jchromb.2008.10.002. [PMID: 18945651]
  • Manuel Rey R Plan, Ivana Saska, Arsenia G Cagauan, David J Craik. Backbone cyclised peptides from plants show molluscicidal activity against the rice pest Pomacea canaliculata (golden apple snail). Journal of agricultural and food chemistry. 2008 Jul; 56(13):5237-41. doi: 10.1021/jf800302f. [PMID: 18557620]
  • E Yas-Natan, G Segev, I Aroch. Clinical, neurological and clinicopathological signs, treatment and outcome of metaldehyde intoxication in 18 dogs. The Journal of small animal practice. 2007 Aug; 48(8):438-43. doi: 10.1111/j.1748-5827.2007.00360.x. [PMID: 17617165]
  • Beth A Valentine, Wilson K Rumbeiha, Terry S Hensley, Richard R Halse. Arsenic and metaldehyde toxicosis in a beef herd. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 2007 Mar; 19(2):212-5. doi: 10.1177/104063870701900216. [PMID: 17402622]
  • Louise C Simms, Julian J C Dawson, Graeme I Paton, Michael J Wilson. Identification of environmental factors limiting plant uptake of metaldehyde seed treatments under field conditions. Journal of agricultural and food chemistry. 2006 May; 54(10):3646-50. doi: 10.1021/jf060231a. [PMID: 19127739]
  • Kazuya Kiyota. [Case report-fatal snail bait (metaldehyde) overdose presenting aspiration pneumonia]. Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology. 2003 Oct; 16(4):453-8. doi: NULL. [PMID: 14740568]
  • Louise C Simms, Christopher E Mullins, Michael J Wilson. Seed dressings to control slug damage in oilseed rape. Pest management science. 2002 Jul; 58(7):687-94. doi: 10.1002/ps.514. [PMID: 12146169]
  • S Shintani, K Goto, Y Endo, C Iwamoto, K Ohata. Adsorption effects of activated charcoal on metaldehyde toxicity in rats. Veterinary and human toxicology. 1999 Feb; 41(1):15-8. doi: NULL. [PMID: 9949477]
  • J P Moody, F G Inglis. Persistence of metaldehyde during acute molluscicide poisoning. Human & experimental toxicology. 1992 Sep; 11(5):361-2. doi: 10.1177/096032719201100510. [PMID: 1358151]
  • H B el-Wakil, M A Radwan. Biochemical studies on the terrestrial snail, Eubania vermiculata (Müller) treated with some pesticides. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 1991; 26(5-6):479-89. doi: 10.1080/03601239109372750. [PMID: 1779124]
  • R A Smith. The determination of volatile carbonyl compounds in diagnostic samples. Veterinary and human toxicology. 1987 Jun; 29(3):244-5. doi: NULL. [PMID: 3604046]
  • T F Booze, F W Oehme. An investigation of metaldehyde and acetaldehyde toxicities in dogs. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1986 Apr; 6(3):440-6. doi: 10.1016/0272-0590(86)90217-4. [PMID: 3084327]
  • T F Booze, F W Oehme. Gas chromatographic analysis of metaldehyde in urine and plasma. Journal of analytical toxicology. 1985 Jul; 9(4):172-3. doi: 10.1093/jat/9.4.172. [PMID: 4033074]
  • C J Griffiths. The determination of metaldehyde in biological material by head-space gas chromatography. Journal of chromatography. 1984 Jul; 295(1):240-7. doi: 10.1016/s0021-9673(01)87619-6. [PMID: 6470086]
  • G ROMAGNY, M MEGARD. [Renal repercussions of metaldehyde poisoning; attempted pathogenetic interpretation]. Journal de medecine de Lyon. 1959 Mar; 40(941):237-42. doi: NULL. [PMID: 13641909]