Difethialone (BioDeep_00000012380)
Volatile Flavor Compounds
代谢物信息卡片
化学式: C31H23BrO2S (538.0602038)
中文名称: 噻鼠灵
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(CC2=CC=CC=C2C1C3=C(SC4=CC=CC=C4C3=O)O)C5=CC=C(C=C5)C6=CC=C(C=C6)Br
InChI: InChI=1S/C31H23BrO2S/c32-24-15-13-20(14-16-24)19-9-11-21(12-10-19)23-17-22-5-1-2-6-25(22)27(18-23)29-30(33)26-7-3-4-8-28(26)35-31(29)34/h1-16,23,27,34H,17-18H2
描述信息
D006401 - Hematologic Agents > D000925 - Anticoagulants > D015110 - 4-Hydroxycoumarins
同义名列表
2 个代谢物同义名
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:81893
- KEGG: C18695
- KEGGdrug: D09807
- PubChem: 91771
- Metlin: METLIN72473
- ChEMBL: CHEMBL3188653
- CAS: 104653-34-1
- PMhub: MS000026691
- PubChem: 124489369
- KNApSAcK: 81893
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Daniel G Nosal, Douglas L Feinstein, Luying Chen, Richard B van Breemen. Separation and Quantification of Superwarfarin Rodenticide Diastereomers-Bromadiolone, Difenacoum, Flocoumafen, Brodifacoum, and Difethialone-in Human Plasma.
Journal of AOAC International.
2020 Jun; 103(3):770-778. doi:
10.1093/jaoacint/qsaa007
. [PMID: 33241367] - Isabelle Fourel, Etienne Benoit, Virginie Lattard. Enantiomeric fraction evaluation of the four stereoisomers of difethialone in biological matrices of rat by two enantioselective liquid chromatography tandem mass spectrometry methods: Chiral stationary phase or derivatization.
Journal of chromatography. A.
2020 May; 1618(?):460848. doi:
10.1016/j.chroma.2019.460848
. [PMID: 31932088] - Georges Jourdi, Sebastien Lefèbvre, Bernard Le Bonniec, Emmanuel Curis, Pascale Gaussem, Virginie Lattard, Virginie Siguret. Thrombin generation test: A reliable tool to evaluate the pharmacodynamics of vitamin K antagonist rodenticides in rats.
Pesticide biochemistry and physiology.
2018 04; 146(?):19-24. doi:
10.1016/j.pestbp.2018.02.004
. [PMID: 29626988] - Jae-chul Jung, Hyung-in Moon. Larvicidal activity of 4-hydroxycoumarin derivatives against Aedes aegypti.
Pharmaceutical biology.
2011 Feb; 49(2):190-3. doi:
10.3109/13880209.2010.507769
. [PMID: 21043993] - Isabelle Fourel, Christophe Hugnet, Isabelle Goy-Thollot, Philippe Berny. Validation of a new liquid chromatography- tandem mass spectrometry ion-trap technique for the simultaneous determination of thirteen anticoagulant rodenticides, drugs, or natural products.
Journal of analytical toxicology.
2010 Mar; 34(2):95-102. doi:
10.1093/jat/34.2.95
. [PMID: 20223102] - V Vandenbroucke, A Bousquet-Melou, P De Backer, S Croubels. Pharmacokinetics of eight anticoagulant rodenticides in mice after single oral administration.
Journal of veterinary pharmacology and therapeutics.
2008 Oct; 31(5):437-45. doi:
10.1111/j.1365-2885.2008.00979.x
. [PMID: 19000263] - Virginie Vandenbroucke, Noël Desmet, Patrick De Backer, Siska Croubels. Multi-residue analysis of eight anticoagulant rodenticides in animal plasma and liver using liquid chromatography combined with heated electrospray ionization tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2008 Jun; 869(1-2):101-10. doi:
10.1016/j.jchromb.2008.05.011
. [PMID: 18502701] - Thomas Grobosch, Boris Angelow, Lena Schönberg, Dagmar Lampe. Acute bromadiolone intoxication.
Journal of analytical toxicology.
2006 May; 30(4):281-6. doi:
10.1093/jat/30.4.281
. [PMID: 16803669] - A Vásquez, M A Rodríguez. [Hemorrhagic syndrome caused by exposure to a rodenticide. Report of a case].
Revista medica de Chile.
2000 Jun; 128(6):647-9. doi:
NULL
. [PMID: 11016065] - E A Kuijpers, J den Hartigh, T J Savelkoul, F A de Wolff. A method for the simultaneous identification and quantitation of five superwarfarin rodenticides in human serum.
Journal of analytical toxicology.
1995 Nov; 19(7):557-62. doi:
10.1093/jat/19.7.557
. [PMID: 8577178] - P J Berny, T Buronfosse, G Lorgue. Anticoagulant poisoning in animals: a simple new high-performance thin-layer chromatographic (HPTLC) method for the simultaneous determination of eight anticoagulant rodenticides in liver samples.
Journal of analytical toxicology.
1995 Nov; 19(7):576-80. doi:
10.1093/jat/19.7.576
. [PMID: 8577181]