QUIZALOFOP-ETHYL (BioDeep_00000012313)

human metabolite blood metabolite

代谢物信息卡片

Ethyl 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propionic acid

化学式: C19H17ClN2O4 (372.0876792)
中文名称: 喹禾灵
谱图信息: 最多检出来源 Homo sapiens(blood) 4.92%

分子结构信息

SMILES: CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl
InChI: InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3

描述信息

CONFIDENCE standard compound; INTERNAL_ID 430; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10197; ORIGINAL_PRECURSOR_SCAN_NO 10195
CONFIDENCE standard compound; INTERNAL_ID 430; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10169; ORIGINAL_PRECURSOR_SCAN_NO 10168
CONFIDENCE standard compound; INTERNAL_ID 430; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10194; ORIGINAL_PRECURSOR_SCAN_NO 10192
CONFIDENCE standard compound; INTERNAL_ID 430; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10142; ORIGINAL_PRECURSOR_SCAN_NO 10140
CONFIDENCE standard compound; INTERNAL_ID 430; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10217; ORIGINAL_PRECURSOR_SCAN_NO 10216
ORIGINAL_ACQUISITION_NO 10194; CONFIDENCE standard compound; INTERNAL_ID 430; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_PRECURSOR_SCAN_NO 10192
CONFIDENCE standard compound; INTERNAL_ID 430; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10226; ORIGINAL_PRECURSOR_SCAN_NO 10224
D010575 - Pesticides > D006540 - Herbicides
D016573 - Agrochemicals

同义名列表

7 个代谢物同义名

Ethyl 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propionic acid; Ethyl 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propionate; ethyl 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate; Quizalofop-ethyl, (R)-isomer; Quizalofop-ethyl, (S)-isomer; quizalofop-P-ethyl; QUIZALOFOP-ETHYL

数据库引用编号

18 个数据库交叉引用编号

ChEBI: CHEBI:137937
ChEBI: CHEBI:81807
KEGG: C18530
PubChem: 53518
HMDB: HMDB0257062
Metlin: METLIN72336
ChEMBL: CHEMBL444825
chemspider: 48336
CAS: 76578-14-8
CAS: 76578-12-6
MoNA: LU043002
MoNA: LU043006
MoNA: LU043001
MoNA: LU043003
MoNA: LU043004
MoNA: LU043005
PMhub: MS000026615
PubChem: 124489204

分类词条

2-phenoxypropionic acid esters

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

9606 - Homo sapiens: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Wen Chen, Sifu Li, Dingyi Bai, Zongfang Li, Haozhe Liu, Lianyang Bai, Lang Pan. Detoxification mechanism of herbicide in Polypogon fugax and its influence on rhizosphere enzyme activities. Ecotoxicology and environmental safety. 2023 Jul; 263(?):115263. doi: 10.1016/j.ecoenv.2023.115263. [PMID: 37473705]
Victor Hugo Vidal Ribeiro, Caio Augusto de Castro Grossi Brunharo, Carol Mallory-Smith, Darrin L Walenta, Judit Barroso. First report of target-site resistance to ACCase-inhibiting herbicides in Bromus tectorum L. Pest management science. 2023 Jun; ?(?):. doi: 10.1002/ps.7607. [PMID: 37309712]
Xue Liu, Jiao Li, Yue Huang, Zhongrong Zhang, Qing Lin, Pengliang Xia, Fanyu Kong, Jun Qiu, Song Fang, Xiude Hua. Rapid and sensitive detection of quizalofop-p-ethyl by gold nanoparticle-based lateral flow immunoassay in agriproducts and environmental samples. The Science of the total environment. 2023 Jan; 857(Pt 1):159427. doi: 10.1016/j.scitotenv.2022.159427. [PMID: 36244486]
Lizhen Zhu, Chengju Wang, Hongyun Jiang, Lan Zhang, Liangang Mao, Yanning Zhang, Suzhen Qi, Xingang Liu. Quizalofop-P-ethyl induced developmental toxicity and cardiotoxicity in early life stage of zebraﬁsh (Danio rerio). Ecotoxicology and environmental safety. 2022 Jun; 238(?):113596. doi: 10.1016/j.ecoenv.2022.113596. [PMID: 35526453]
Jingchao Chen, Shouhui Wei, Hongjuan Huang, Hailan Cui, Chaoxian Zhang, Xiangju Li. Characterization of glyphosate and quizalofop-p-ethyl multiple resistance in Eleusine indica. Pesticide biochemistry and physiology. 2021 Jul; 176(?):104862. doi: 10.1016/j.pestbp.2021.104862. [PMID: 34119213]
Wen Chen, Lamei Wu, Junzhi Wang, Qin Yu, Lianyang Bai, Lang Pan. Quizalofop-p-ethyl resistance in Polypogon fugax involves glutathione S-transferases. Pest management science. 2020 Nov; 76(11):3800-3805. doi: 10.1002/ps.5931. [PMID: 32476196]
Shuo Wang, Zhiguang Hou, Shuang Liang, Zhongbin Lu. Residue Behavior and Risk Assessment of Rimsulfuron and Quizalofop-P-ethyl in Potato Under Field Conditions. Bulletin of environmental contamination and toxicology. 2020 Oct; 105(4):602-606. doi: 10.1007/s00128-020-03002-9. [PMID: 32978647]
Bingqi Liu, Fei Ding, Mingliang Wang, Fei Wang, Xiaoyong Luo, Lingxu Li. Cross-resistance pattern to ACCase-inhibiting herbicides in a novel Trp1999Leu mutation American sloughgrass (Beckmannia syzigachne) population. Pesticide biochemistry and physiology. 2019 Sep; 159(?):80-84. doi: 10.1016/j.pestbp.2019.05.019. [PMID: 31400787]
Martina Biserni, Robin Mesnage, Raquel Ferro, Eva Wozniak, Theodoros Xenakis, Charles A Mein, Michael N Antoniou. Quizalofop-p-Ethyl Induces Adipogenesis in 3T3-L1 Adipocytes. Toxicological sciences : an official journal of the Society of Toxicology. 2019 08; 170(2):452-461. doi: 10.1093/toxsci/kfz097. [PMID: 31086981]
Catalin Aurelian Rosculete, Elena Bonciu, Elena Rosculete, Liviu Aurel Olaru. Determination of the Environmental Pollution Potential of Some Herbicides by the Assessment of Cytotoxic and Genotoxic Effects on Allium cepa. International journal of environmental research and public health. 2018 12; 16(1):. doi: 10.3390/ijerph16010075. [PMID: 30597898]
Li-Zhen Zhu, Su-Zhen Qi, Fang-Jie Cao, Xi-Yan Mu, Yang Yang, Chengju Wang. Quizalofop-P-ethyl exposure increases estrogen axis activity in male and slightly decreases estrogen axis activity in female zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 2017 Feb; 183(?):76-84. doi: 10.1016/j.aquatox.2016.12.011. [PMID: 28027508]
Nikolaos Mantzos, Anastasia Karakitsou, Sofia Nikolaki, Eleni Leneti, Ioannis Konstantinou. Dissipation and transport of quizalofop-p-ethyl herbicide in sunflower cultivation under field conditions. Environmental science and pollution research international. 2016 Feb; 23(4):3481-90. doi: 10.1007/s11356-015-5572-6. [PMID: 26490927]
Wenlei Guo, Guohui Yuan, Weitang Liu, Yaling Bi, Long Du, Chao Zhang, Qi Li, Jinxin Wang. Multiple resistance to ACCase and AHAS-inhibiting herbicides in shortawn foxtail (Alopecurus aequalis Sobol.) from China. Pesticide biochemistry and physiology. 2015 Oct; 124(?):66-72. doi: 10.1016/j.pestbp.2015.04.006. [PMID: 26453232]
Yiran Liang, Peng Wang, Donghui Liu, Zhigang Shen, Hui Liu, Zhixin Jia, Zhiqiang Zhou. Enantioselective metabolism of quizalofop-ethyl in rat. PloS one. 2014; 9(6):e101052. doi: 10.1371/journal.pone.0101052. [PMID: 24964043]
Zeynep B Doganlar. Quizalofop-p-ethyl-induced phytotoxicity and genotoxicity in Lemna minor and Lemna gibba. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering. 2012; 47(11):1631-43. doi: 10.1080/10934529.2012.687175. [PMID: 22702823]
Munees Ahemad, Mohammad Saghir Khan. Phosphate-solubilizing and plant-growth-promoting Pseudomonas aeruginosa PS1 improves greengram performance in quizalafop-p-ethyl and clodinafop amended soil. Archives of environmental contamination and toxicology. 2010 Feb; 58(2):361-72. doi: 10.1007/s00244-009-9382-z. [PMID: 19756846]
Munees Ahemad, Mohammad Saghir Khan. Toxicity assessment of herbicides quizalafop-p-ethyl and clodinafop towards Rhizobium pea symbiosis. Bulletin of environmental contamination and toxicology. 2009 Jun; 82(6):761-6. doi: 10.1007/s00128-009-9692-x. [PMID: 19290455]
Xiao-Hong Cao, Song-Yao Li, Chun-Ling Wang, Mei-Fang Lu. [Potential use of the herbicide quizalofop-p-ethyl for eicosapentaenoic acid overproduction by the diatom Nitzschia laevis]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 2007 Sep; 23(5):885-90. doi: 10.1016/s1872-2075(07)60055-7. [PMID: 18051870]
Lindsey J Price, Derek Herbert, David J Cole, John L Harwood. Use of plant cell cultures to study graminicide effects on lipid metabolism. Phytochemistry. 2003 Jul; 63(5):533-41. doi: 10.1016/s0031-9422(03)00180-8. [PMID: 12809713]
D Herbert, D J Cole, K E Pallett, J L Harwood. Differential sensitivity of lipid metabolism in monocotyledons to grass-specific herbicides. Biochemical Society transactions. 1993 May; 21(2):183S. doi: 10.1042/bst021183s. [PMID: 8359436]