PROFENOFOS (BioDeep_00000012265)
代谢物信息卡片
PROFENOFOS
化学式: C11H15BrClO3PS (371.9351380000001)
中文名称: 丙溴磷
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCSP(=O)(OCC)OC1=C(C=C(C=C1)Br)Cl
InChI: InChI=1S/C11H15BrClO3PS/c1-3-7-18-17(14,15-4-2)16-11-6-5-9(12)8-10(11)13/h5-6,8H,3-4,7H2,1-2H3
描述信息
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals
同义名列表
2 个代谢物同义名
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:38845
- KEGG: C18404
- PubChem: 38779
- Metlin: METLIN72212
- ChEMBL: CHEMBL2138242
- CAS: 81116-98-5
- CAS: 81123-19-5
- CAS: 41198-08-7
- PMhub: MS000026564
- PubChem: 124489078
- RefMet: Profenofos
- KNApSAcK: 38845
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Genrong Zhang, Jingfeng Xue, Yufei Zhang, Jia Ye, Nan Zhang, Liancheng Fang, Taozhong Shi, Xin Ma, Hui Li, Rimao Hua. Significantly enhanced biodegradation of profenofos by Cupriavidus nantongensis X1T mediated by walnut shell biochar.
Journal of hazardous materials.
2024 Apr; 468(?):133750. doi:
10.1016/j.jhazmat.2024.133750. [PMID: 38368682] - Zeinab M El-Bouhy, Fatma A S Mohamed, Mohamed W A Elashhab, Walaa El-Houseiny. Toxicity bioassay and sub-lethal effects of profenofos-based insecticide on behavior, biochemical, hematological, and histopathological responses in Grass carp (Ctenopharyngodon idella).
Ecotoxicology (London, England).
2023 Mar; 32(2):196-210. doi:
10.1007/s10646-023-02628-9. [PMID: 36708414] - Najeeba Paree Paker, Shehzad Mehmood, Muhammad Tariq Javed, Christos A Damalas, Fazal Ur Rehman, Hassan Javed Chaudhary, Muhammad Zeshan Munir, Mahrukh Malik. Elucidating molecular characterization of chlorpyrifos and profenofos degrading distinct bacterial strains for enhancing seed germination potential of Gossypium arboreum L.
Environmental science and pollution research international.
2023 Feb; ?(?):. doi:
10.1007/s11356-023-25343-8. [PMID: 36752920] - Jeevan Dhanarisi, Tanita Maria Tzotzolaki, Ana-Mariya D Vasileva, Matti A Kjellberg, Hanna Hakulinen, Paula Vanninen, Indika Gawarammana, Fahim Mohamed, Knut Erik Hovda, Michael Eddleston. Osmolal and anion gaps after acute self-poisoning with agricultural formulations of the organophosphorus insecticides profenofos and diazinon: A pilot study.
Basic & clinical pharmacology & toxicology.
2022 Feb; 130(2):320-327. doi:
10.1111/bcpt.13686. [PMID: 34796663] - Muhammad Usman Ghani, Hafiz Naeem Asghar, Abdullah Niaz, Zahir Ahmad Zahir, Muhammad Farrakh Nawaz, Max M Häggblom. Efficacy of rhizobacteria for degradation of profenofos and improvement in tomato growth.
International journal of phytoremediation.
2022; 24(5):463-473. doi:
10.1080/15226514.2021.1952927. [PMID: 34304658] - Isaac Omwenga, Shensheng Zhao, Laetitia Kanja, Hans Mol, Ivonne M C M Rietjens, Jochem Louisse. Prediction of dose-dependent in vivo acetylcholinesterase inhibition by profenofos in rats and humans using physiologically based kinetic (PBK) modeling-facilitated reverse dosimetry.
Archives of toxicology.
2021 04; 95(4):1287-1301. doi:
10.1007/s00204-021-03004-4. [PMID: 33651127] - Amany Abdel-Rahman Mohamed, Afaf N Abdel Rahman, Hesham H Mohammed, Lamiaa L M Ebraheim, Azza M A Abo-ElMaaty, Sozan A Ali, Walaa M Elhady. Neurobehavioral, apoptotic, and DNA damaging effects of sub-chronic profenofos exposure on the brain tissue of Cyprinus carpio L.: Antagonistic role of Geranium essential oil.
Aquatic toxicology (Amsterdam, Netherlands).
2020 Jul; 224(?):105493. doi:
10.1016/j.aquatox.2020.105493. [PMID: 32408004] - Sonia Díaz-Criollo, Marien Palma, Andrés A Monroy-García, Alvaro J Idrovo, David Combariza, Marcela E Varona-Uribe. Chronic pesticide mixture exposure including paraquat and respiratory outcomes among Colombian farmers.
Industrial health.
2020 Feb; 58(1):15-21. doi:
10.2486/indhealth.2018-0111. [PMID: 30996154] - Vinay Kumar, Neha Sharma, S S Maitra, Sivarama Krishna Lakkaboyana. In vivo removal of profenofos in agricultural soil and plant growth promoting activity on Vigna radiata by efficient bacterial formulation.
International journal of phytoremediation.
2020; 22(6):585-593. doi:
10.1080/15226514.2019.1696743. [PMID: 31823647] - Waqas Wakil, Muhammad Yasin, Mirza Abdul Qayyum, Muhammad Usman Ghazanfar, Abdullah M Al-Sadi, Geoffrey O Bedford, Yong Jung Kwon. Resistance to commonly used insecticides and phosphine fumigant in red palm weevil, Rhynchophorus ferrugineus (Olivier) in Pakistan.
PloS one.
2018; 13(7):e0192628. doi:
10.1371/journal.pone.0192628. [PMID: 30024882] - Shaogang Chu, Margaret R Baker, Gladys Leong, Robert J Letcher, Shirley J Gee, Bruce D Hammock, Qing X Li. Exploring adduct formation between human serum albumin and eleven organophosphate ester flame retardants and plasticizers using MALDI-TOF/TOF and LC-Q/TOF.
Chemosphere.
2017 Aug; 180(?):169-177. doi:
10.1016/j.chemosphere.2017.03.124. [PMID: 28407546] - Thitirat Nganchamung, Mark G Robson, Wattasit Siriwong. Association between blood cholinesterase activity, organophosphate pesticide residues on hands, and health effects among chili farmers in Ubon Ratchathani Province, northeastern Thailand.
Roczniki Panstwowego Zakladu Higieny.
2017 ; 68(2):175-183. doi:
NULL. [PMID: 28646835] - Fayez A Bakry, Karem El-Hommossany, Mahmoud Abd El-Atti, Somaya M Ismail. Alterations in the fatty acid profile, antioxidant enzymes and protein pattern of Biomphalaria alexandrina snails exposed to the pesticides diazinon and profenfos.
Toxicology and industrial health.
2016 Apr; 32(4):666-76. doi:
10.1177/0748233713506770. [PMID: 24215063] - Steven T Singleton, Pamela J Lein, Oswald A Dadson, Barbara P McGarrigle, Fayssal M Farahat, Taghreed Farahat, Matthew R Bonner, Richard A Fenske, Kit Galvin, Michael R Lasarev, W Kent Anger, Diane S Rohlman, James R Olson. Longitudinal assessment of occupational exposures to the organophosphorous insecticides chlorpyrifos and profenofos in Egyptian cotton field workers.
International journal of hygiene and environmental health.
2015 Mar; 218(2):203-11. doi:
10.1016/j.ijheh.2014.10.005. [PMID: 25466362] - Ghazala, Shahid Mahboob, L Ahmad, S Sultana, K Alghanim, F Al-Misned, Z Ahmad. Fish cholinesterases as biomarkers of sublethal effects of organophosphorus and carbamates in tissues of Labeo rohita.
Journal of biochemical and molecular toxicology.
2014 Mar; 28(3):137-42. doi:
10.1002/jbt.21545. [PMID: 24357265] - Oswald A Dadson, Corie A Ellison, Steven T Singleton, Lai-Har Chi, Barbara P McGarrigle, Pamela J Lein, Fayssal M Farahat, Taghreed Farahat, James R Olson. Metabolism of profenofos to 4-bromo-2-chlorophenol, a specific and sensitive exposure biomarker.
Toxicology.
2013 Apr; 306(?):35-9. doi:
10.1016/j.tox.2013.01.023. [PMID: 23415833] - John E Casida. The greening of pesticide-environment interactions: some personal observations.
Environmental health perspectives.
2012 Apr; 120(4):487-93. doi:
10.1289/ehp.1104405. [PMID: 22472325] - Poonam Sharma, Rambir Singh. Dichlorvos and lindane induced oxidative stress in rat brain: Protective effects of ginger.
Pharmacognosy research.
2012 Jan; 4(1):27-32. doi:
10.4103/0974-8490.91031. [PMID: 22224058] - Harald John, Felicitas Breyer, Jörg Oliver Thumfart, Hans Höchstetter, Horst Thiermann. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for detection and identification of albumin phosphylation by organophosphorus pesticides and G- and V-type nerve agents.
Analytical and bioanalytical chemistry.
2010 Nov; 398(6):2677-91. doi:
10.1007/s00216-010-4076-y. [PMID: 20730528] - Robinson H Mdegela, Resto D Mosha, Morten Sandvik, Janneche U Skaare. Assessment of acetylcholinesterase activity in Clarias gariepinus as a biomarker of organophosphate and carbamate exposure.
Ecotoxicology (London, England).
2010 Jun; 19(5):855-63. doi:
10.1007/s10646-010-0466-3. [PMID: 20169407] - Jiang He, Mingtao Fan, Xianjin Liu. Environmental behavior of profenofos under paddy field conditions.
Bulletin of environmental contamination and toxicology.
2010 Jun; 84(6):771-4. doi:
10.1007/s00128-010-0023-z. [PMID: 20437027] - Jérôme Carletto, Thibaud Martin, Flavie Vanlerberghe-Masutti, Thierry Brévault. Insecticide resistance traits differ among and within host races in Aphis gossypii.
Pest management science.
2010 Mar; 66(3):301-7. doi:
10.1002/ps.1874. [PMID: 19908228] - Atef M Al-Attar. Physiological and histopathological investigations on the effects of alpha-lipoic acid in rats exposed to malathion.
Journal of biomedicine & biotechnology.
2010; 2010(?):203503. doi:
10.1155/2010/203503. [PMID: 20454535] - Susmita Ganguly, Sima Bhattacharya, Sukumar Mandi, Jayanta Tarafdar. Biological detection and analysis of toxicity of organophosphate- and azadirachtin-based insecticides in Lathyrus sativus L.
Ecotoxicology (London, England).
2010 Jan; 19(1):85-95. doi:
10.1007/s10646-009-0391-5. [PMID: 19618265] - Ahmed A Romeh, Tarek M Mekky, Rady A Ramadan, Mohamed Y Hendawi. Dissipation of profenofos, imidacloprid and penconazole in tomato fruits and products.
Bulletin of environmental contamination and toxicology.
2009 Dec; 83(6):812-7. doi:
10.1007/s00128-009-9852-z. [PMID: 19760343] - Joseph Achaleke, Thibaud Martin, Richard T Ghogomu, Maurice Vaissayre, Thierry Brévault. Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa.
Pest management science.
2009 Oct; 65(10):1147-54. doi:
10.1002/ps.1807. [PMID: 19548293] - P Kavitha, J Venkateswara Rao. Sub-lethal effects of profenofos on tissue-specific antioxidative responses in a Euryhyaline fish, Oreochromis mossambicus.
Ecotoxicology and environmental safety.
2009 Sep; 72(6):1727-33. doi:
10.1016/j.ecoenv.2009.05.010. [PMID: 19501401] - Soon-Il Kim, Young-Eun Na, Ji-Hwan Yi, Byung-Seok Kim, Young-Joon Ahn. Contact and fumigant toxicity of oriental medicinal plant extracts against Dermanyssus gallinae (Acari: Dermanyssidae).
Veterinary parasitology.
2007 Apr; 145(3-4):377-82. doi:
10.1016/j.vetpar.2006.12.021. [PMID: 17289270] - H A Mesbah, A S A Saad, A K Mourad, F A Taman, I B Mohamed. Joint action of quercetin with four insecticides on the cotton leaf-worm larvae, Spodoptera littoralis Boisd. (Lep. : Noctuidae) in Egypt.
Communications in agricultural and applied biological sciences.
2007; 72(3):445-57. doi:
". [PMID: 18399473] - Daniel K Nomura, Kathleen A Durkin, Kyle P Chiang, Gary B Quistad, Benjamin F Cravatt, John E Casida. Serine hydrolase KIAA1363: toxicological and structural features with emphasis on organophosphate interactions.
Chemical research in toxicology.
2006 Sep; 19(9):1142-50. doi:
10.1021/tx060117m. [PMID: 16978018] - Cristina S Bastos, Raul P de Almeida, Fábio A Suinaga. Selectivity of pesticides used on cotton (Gossypium hirsutum) to Trichogramma pretiosum reared on two laboratory-reared hosts.
Pest management science.
2006 Jan; 62(1):91-8. doi:
10.1002/ps.1140. [PMID: 16308868] - H A Mesbah, A K Mourad, A Z M Rokaia. Efficacy of some plant oils alone and/or combined with different insecticides on the cotton leaf-worm Spodoptera littoralis (Boisd.) (Lepidoptera: Noctuidae) in Egypt.
Communications in agricultural and applied biological sciences.
2006; 71(2 Pt B):305-28. doi:
". [PMID: 17385497] - Gary B Quistad, Karl J Fisher, Sarah C Owen, Rebecka Klintenberg, John E Casida. Platelet-activating factor acetylhydrolase: selective inhibition by potent n-alkyl methylphosphonofluoridates.
Toxicology and applied pharmacology.
2005 Jun; 205(2):149-56. doi:
10.1016/j.taap.2004.09.018. [PMID: 15893542] - S M Dogheim, El M M Ashraf, S A G Alla, M A Khorshid, S M Fahmy. Pesticides and heavy metals levels in Egyptian leafy vegetables and some aromatic medicinal plants.
Food additives and contaminants.
2004 Apr; 21(4):323-30. doi:
10.1080/02652030310001656361. [PMID: 15204556] - K Talebi, M R Ghassami. Residues of profenofos in spring onion.
Communications in agricultural and applied biological sciences.
2004; 69(4):799-802. doi:
". [PMID: 15756871] - Yahia Y Mosleh, Saad M M Ismail, Mohamed T Ahmed, Yousery M Ahmed. Comparative toxicity and biochemical responses of certain pesticides to the mature earthworm Aporrectodea caliginosa under laboratory conditions.
Environmental toxicology.
2003 Oct; 18(5):338-46. doi:
10.1002/tox.10134. [PMID: 14502587] - Li Lin, Jun Liu, Kai Zhang, Yanjun Chen. [An experimental study of the effects of profenofos on antioxidase in rabbits].
Wei sheng yan jiu = Journal of hygiene research.
2003 Sep; 32(5):434-5. doi:
NULL. [PMID: 14650183] - Hafez El Kady, Gregor J Devine. Insecticide resistance in Egyptian populations of the cotton whitefly, Bemisia tabaci (Hemiptera: Aleyrodidae).
Pest management science.
2003 Aug; 59(8):865-71. doi:
10.1002/ps.687. [PMID: 12916767] - M Gotoh, M Sakata, T Endo, H Hayashi, H Seno, O Suzuki. Profenofos metabolites in human poisoning.
Forensic science international.
2001 Feb; 116(2-3):221-6. doi:
10.1016/s0379-0738(00)00377-7. [PMID: 11182275] - E Murali Mohan, M Rajaran Gayathri, D Amirtha Ganesh, C A Banu Priya, A Arun Sam Lal, V Amalan Stanley, K Sadasivan Pillai, P Balakrishnamurthy. Elucidation of tumor-promoting potential of a combination pesticide by short-term, in vivo bioassay.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.
2001; 20(3):229-36. doi:
". [PMID: 11797832] - S E Sparks, G B Quistad, J E Casida. Organophosphorus pesticide-induced butyrylcholinesterase inhibition and potentiation of succinylcholine toxicity in mice.
Journal of biochemical and molecular toxicology.
1999; 13(2):113-8. doi:
10.1002/(sici)1099-0461(1999)13:2<113::aid-jbt7>3.0.co;2-8. [PMID: 9890196] - K Lakew, Y Mekonnen. The health status of northern Omo State Farm workers exposed to chlorpyrifos and profenofos.
Ethiopian medical journal.
1998 Jul; 36(3):175-84. doi:
NULL. [PMID: 10214458] - H Seno, H Hattori, T Kumazawa, A Ishii, K Watanabe, O Suzuki. Quantitation of postmortem profenofos levels.
Journal of toxicology. Clinical toxicology.
1998; 36(1-2):63-5. doi:
10.3109/15563659809162588. [PMID: 9541046] - T A el-Aziz. Monitoring of some pesticides residues in different samples of meat and some organs of cattle.
The Journal of the Egyptian Public Health Association.
1996; 71(3-4):343-53. doi:
NULL. [PMID: 17217017] - E Enan, I G Berberian, S el-Fiki, M el-Masry, O H Enan. Effects of two organophosphorus insecticides on some biochemical constituents in the nervous system and liver of rabbits.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
1987 Apr; 22(2):149-70. doi:
10.1080/03601238709372551. [PMID: 3584839]