Pentachlorobenzene (BioDeep_00000012109)

 

Secondary id: BioDeep_00001867906

human metabolite blood metabolite


代谢物信息卡片


Benzene,1,2,3,4,5-pentachloro-

化学式: C6HCl5 (247.8520896)
中文名称: 五氯苯
谱图信息: 最多检出来源 Homo sapiens(blood) 91.67%

分子结构信息

SMILES: C1=C(C(=C(C(=C1Cl)Cl)Cl)Cl)Cl
InChI: InChI=1S/C6HCl5/c7-2-1-3(8)5(10)6(11)4(2)9/h1H

描述信息

D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals

同义名列表

6 个代谢物同义名

Benzene,1,2,3,4,5-pentachloro-; 1,2,3,4,5-PENTACHLOROBENZENE; PENTACHLOROBENZENE; Pentachlorbenzol; QCB; PCB



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Carolina Lourencetti, Marina Ricci. Determination of organochlorine priority substances in fish tissue: Optimisation of the clean-up step balancing removal of lipids with analytes' recovery. Journal of chromatography. A. 2020 May; 1619(?):460944. doi: 10.1016/j.chroma.2020.460944. [PMID: 32059868]
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  • Darol E Dodd, Linda J Pluta, Mark A Sochaski, Deborah A Banas, Russell S Thomas. Subchronic hepatotoxicity evaluation of 2,3,4,6-tetrachlorophenol in sprague dawley rats. Journal of toxicology. 2012; 2012(?):376246. doi: 10.1155/2012/376246. [PMID: 22666246]
  • Zhiqiang Nie, Minghui Zheng, Wenbin Liu, Bing Zhang, Guorui Liu, Guijin Su, Pu Lv, Ke Xiao. Estimation and characterization of PCDD/Fs, dl-PCBs, PCNs, HxCBz and PeCBz emissions from magnesium metallurgy facilities in China. Chemosphere. 2011 Dec; 85(11):1707-12. doi: 10.1016/j.chemosphere.2011.09.016. [PMID: 22024095]
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  • Larry L Needham, Philippe Grandjean, Birger Heinzow, Poul J Jørgensen, Flemming Nielsen, Donald G Patterson, Andreas Sjödin, Wayman E Turner, Pal Weihe. Partition of environmental chemicals between maternal and fetal blood and tissues. Environmental science & technology. 2011 Feb; 45(3):1121-6. doi: 10.1021/es1019614. [PMID: 21166449]
  • José Robles-Molina, Bienvenida Gilbert-López, Juan F García-Reyes, Antonio Molina-Díaz. Determination of organic priority pollutants in sewage treatment plant effluents by gas chromatography high-resolution mass spectrometry. Talanta. 2010 Sep; 82(4):1318-24. doi: 10.1016/j.talanta.2010.06.053. [PMID: 20801335]
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  • Cui-ying Liu, Xin Jiang, Xing-lun Yang, Yang Song. [Evaluation of bioavailability of hexachlorobenzene and pentachlorobenzene to rice roots in soils by accelerated solvent extraction]. Huan jing ke xue= Huanjing kexue. 2010 May; 31(5):1352-8. doi: ". [PMID: 20623876]
  • Stefan Moss, Jennifer M Keller, Sean Richards, Thomas P Wilson. Concentrations of persistent organic pollutants in plasma from two species of turtle from the Tennessee River Gorge. Chemosphere. 2009 Jun; 76(2):194-204. doi: 10.1016/j.chemosphere.2009.03.054. [PMID: 19406450]
  • Daniel Carrizo, Joan O Grimalt, Nuria Ribas-Fito, Maties Torrent, Jordi Sunyer. Pentachlorobenzene, hexachlorobenzene, and pentachlorophenol in children's serum from industrial and rural populations after restricted use. Ecotoxicology and environmental safety. 2008 Sep; 71(1):260-6. doi: 10.1016/j.ecoenv.2007.08.021. [PMID: 17935782]
  • Rosa Ma González-Rodríguez, Raquel Rial-Otero, Beatriz Cancho-Grande, Jesús Simal-Gándara. Determination of 23 pesticide residues in leafy vegetables using gas chromatography-ion trap mass spectrometry and analyte protectants. Journal of chromatography. A. 2008 Jul; 1196-1197(?):100-9. doi: 10.1016/j.chroma.2008.02.087. [PMID: 18343389]
  • Víctor Matamoros, Jaume Puigagut, Joan García, Josep M Bayona. Behavior of selected priority organic pollutants in horizontal subsurface flow constructed wetlands: a preliminary screening. Chemosphere. 2007 Nov; 69(9):1374-80. doi: 10.1016/j.chemosphere.2007.05.012. [PMID: 17590410]
  • Xinglun Yang, Xin Jiang, Guifen Yu, Fenxia Yao, Yongrong Bian, Fang Wang. Leaf-air transfer of organochlorine pesticides from three selected vegetables. Environmental pollution (Barking, Essex : 1987). 2007 Jul; 148(2):555-61. doi: 10.1016/j.envpol.2006.11.029. [PMID: 17257723]
  • Heqing Shen, Katharina M Main, Helena E Virtanen, Ida N Damggard, Anne-Maarit Haavisto, M Kaleva, K A Boisen, Ida M Schmidt, Marla Chellakooty, Niels E Skakkebaek, Jorma Toppari, Karl-Werner Schramm. From mother to child: investigation of prenatal and postnatal exposure to persistent bioaccumulating toxicants using breast milk and placenta biomonitoring. Chemosphere. 2007 Apr; 67(9):S256-62. doi: 10.1016/j.chemosphere.2006.05.106. [PMID: 17207515]
  • Ida N Damgaard, Niels E Skakkebaek, Jorma Toppari, Helena E Virtanen, Heqing Shen, Karl-Werner Schramm, Jørgen H Petersen, Tina K Jensen, Katharina M Main. Persistent pesticides in human breast milk and cryptorchidism. Environmental health perspectives. 2006 Jul; 114(7):1133-8. doi: 10.1289/ehp.8741. [PMID: 16835070]
  • Daniel Carrizo, Joan O Grimalt, Nuria Ribas-Fito, Jordi Sunyer, Maties Torrent. Physical-chemical and maternal determinants of the accumulation of organochlorine compounds in four-year-old children. Environmental science & technology. 2006 Mar; 40(5):1420-6. doi: 10.1021/es0518427. [PMID: 16568751]
  • Jonathan Verreault, Derek C G Muir, Ross J Norstrom, Ian Stirling, Aaron T Fisk, Geir W Gabrielsen, Andrew E Derocher, Thomas J Evans, Rune Dietz, Christian Sonne, Gregory M Sandala, Wouter Gebbink, Frank F Riget, Erik W Born, Mitch K Taylor, John Nagy, Robert J Letcher. Chlorinated hydrocarbon contaminants and metabolites in polar bears (Ursus maritimus) from Alaska, Canada, East Greenland, and Svalbard: 1996-2002. The Science of the total environment. 2005 Dec; 351-352(?):369-90. doi: 10.1016/j.scitotenv.2004.10.031. [PMID: 16115663]
  • Mike Howsam, Joan O Grimalt, Elisabet Guinó, Matilde Navarro, Juan Martí-Ragué, Miguel A Peinado, Gabriel Capellá, Victor Moreno. Organochlorine exposure and colorectal cancer risk. Environmental health perspectives. 2004 Nov; 112(15):1460-6. doi: 10.1289/ehp.7143. [PMID: 15531428]
  • Juan C Sanchez-Hernandez, F Borghini, A Corral, J O Grimalt. Field uptake rates of hydrophobic organic contaminants by semipermeable membrane devices: environmental monitoring considerations. Journal of environmental monitoring : JEM. 2004 Nov; 6(11):919-25. doi: 10.1039/b405906a. [PMID: 15536507]
  • Carol D Swartz, K C Donnelly, Arif Islamzadeh, Gilbert T Rowe, William J Rogers, Grigoriy M Palatnikov, Arif A Mekhtiev, Rafik Kasimov, Thomas J McDonald, Jeffery K Wickliffe, Bobby J Presley, John W Bickham. Chemical contaminants and their effects in fish and wildlife from the industrial zone of Sumgayit, Republic of Azerbaijan. Ecotoxicology (London, England). 2003 Dec; 12(6):509-21. doi: 10.1023/b:ectx.0000003038.02643.08. [PMID: 14680332]
  • Jasna Dmitrovic, Siu C Chan, Sylvia H Y Chan. Analysis of pesticides and PCB congeners in serum by GC/MS with SPE sample cleanup. Toxicology letters. 2002 Aug; 134(1-3):253-8. doi: 10.1016/s0378-4274(02)00173-x. [PMID: 12191885]
  • Branislav Vrana, Gerrit Schüürmann. Calibrating the uptake kinetics of semipermeable membrane devices in water: impact of hydrodynamics. Environmental science & technology. 2002 Jan; 36(2):290-6. doi: 10.1021/es0100625. [PMID: 11827065]
  • P Popp, L Brüggemann, P Keil, U Thuss, H Weiss. Chlorobenzenes and hexachlorocyclohexanes (HCHs) in the atmosphere of Bitterfeld and Leipzig (Germany). Chemosphere. 2000 Sep; 41(6):849-55. doi: 10.1016/s0045-6535(99)00531-7. [PMID: 10864157]
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  • S Ikegami, K Umegaki, Y Kawashima, T Ichikawa. Viscous indigestible polysaccharides reduce accumulation of pentachlorobenzene in rats. The Journal of nutrition. 1994 May; 124(5):754-60. doi: 10.1093/jn/124.5.754. [PMID: 8169669]
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  • K Umegaki, S Ikegami, T Ichikawa. Effects of restricted feeding on the absorption, metabolism, and accumulation of pentachlorobenzene in rats. Journal of nutritional science and vitaminology. 1993 Feb; 39(1):11-22. doi: 10.3177/jnsv.39.11. [PMID: 8509897]
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