2,3,3',4,4'-Pentachlorobiphenyl (BioDeep_00000012090)

 

Secondary id: BioDeep_00001868330

human metabolite blood metabolite Industrial Pollutants


代谢物信息卡片


1,2,3-trichloro-4-(3,4-dichlorophenyl)benzene

化学式: C12H5Cl5 (323.8834)
中文名称: 2,3,3,4,4-五氯联苯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=C(C=C1C2=C(C(=C(C=C2)Cl)Cl)Cl)Cl)Cl
InChI: InChI=1S/C12H5Cl5/c13-8-3-1-6(5-10(8)15)7-2-4-9(14)12(17)11(7)16/h1-5H

描述信息

D004785 - Environmental Pollutants > D011078 - Polychlorinated Biphenyls

同义名列表

7 个代谢物同义名

1,2,3-trichloro-4-(3,4-dichlorophenyl)benzene; 2,3,3,4,4-Pentachlorobiphenyl; 2,3,4,3,4-Pentachlorobiphenyl; 2,3,3,4,4-PCB; PCB 105; PCB-105; 2,3,4,3',4'-Pentachlorobiphenyl



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

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1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Elena Raffetti, Carolina Donat-Vargas, Sara Mentasti, Annalisa Chinotti, Francesco Donato. Association between exposure to polychlorinated biphenyls and risk of hypertension: A systematic review and meta-analysis. Chemosphere. 2020 Sep; 255(?):126984. doi: 10.1016/j.chemosphere.2020.126984. [PMID: 32679627]
  • Yan Bao, Lei Zhang, Xin Liu, Lei Shi, Jingguang Li, Guimin Meng, Yunfeng Zhao, Yongning Wu. Dioxin-like compounds in paired maternal serum and breast milk under long sampling intervals. Ecotoxicology and environmental safety. 2020 May; 194(?):110339. doi: 10.1016/j.ecoenv.2020.110339. [PMID: 32143103]
  • Esther Ng, Samira Salihovic, P Monica Lind, Anubha Mahajan, Anne-Christine Syvänen, Tomas Axelsson, Erik Ingelsson, Cecilia M Lindgren, Bert van Bavel, Andrew P Morris, Lars Lind. Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample. Environmental research. 2015 Jul; 140(?):95-101. doi: 10.1016/j.envres.2015.03.022. [PMID: 25839716]
  • L L Aylward, J J Collins, K M Bodner, M Wilken, C M Bodnar. 'Intrinsic' elimination rate and dietary intake estimates for selected indicator PCBs: toxicokinetic modeling using serial sampling data in US subjects, 2005-2010. Chemosphere. 2014 Sep; 110(?):48-52. doi: 10.1016/j.chemosphere.2014.03.070. [PMID: 24880598]
  • Edward F Fitzgerald, Srishti Shrestha, Patrick M Palmer, Lloyd R Wilson, Erin E Belanger, Marta I Gomez, Michael R Cayo, Syni-An Hwang. Polychlorinated biphenyls (PCBs) in indoor air and in serum among older residents of upper Hudson River communities. Chemosphere. 2011 Sep; 85(2):225-31. doi: 10.1016/j.chemosphere.2011.06.027. [PMID: 21724230]
  • Matt Cave, Savitri Appana, Mihir Patel, Keith Cameron Falkner, Craig J McClain, Guy Brock. Polychlorinated biphenyls, lead, and mercury are associated with liver disease in American adults: NHANES 2003-2004. Environmental health perspectives. 2010 Dec; 118(12):1735-42. doi: 10.1289/ehp.1002720. [PMID: 21126940]
  • Renée Dallaire, Eric Dewailly, Daria Pereg, Serge Dery, Pierre Ayotte. Thyroid function and plasma concentrations of polyhalogenated compounds in Inuit adults. Environmental health perspectives. 2009 Sep; 117(9):1380-6. doi: 10.1289/ehp.0900633. [PMID: 19750101]
  • Hirokazu Uemura, Kokichi Arisawa, Mineyoshi Hiyoshi, Atsushi Kitayama, Hidenobu Takami, Fusakazu Sawachika, Satoru Dakeshita, Kentaro Nii, Hiroshi Satoh, Yoshio Sumiyoshi, Kenji Morinaga, Kazunori Kodama, Taka-ichiro Suzuki, Masaki Nagai, Tsuguyoshi Suzuki. Prevalence of metabolic syndrome associated with body burden levels of dioxin and related compounds among Japan's general population. Environmental health perspectives. 2009 Apr; 117(4):568-73. doi: 10.1289/ehp.0800012. [PMID: 19440495]
  • Nobuyuki Koga, Hiroaki Kuroki, Koichi Haraguchi, Tomoyo Kanamaru, Yoshihisa Kato, Ryohei Kimura. [Metabolism of 2,3,3',4,4'-pentachlorobiphenyl in hamsters]. Fukuoka igaku zasshi = Hukuoka acta medica. 2003 May; 94(5):174-82. doi: NULL. [PMID: 12872719]
  • Ilonka A T M Meerts, Yvonne Assink, Peter H Cenijn, Johannes H J Van Den Berg, Bert M Weijers, Ake Bergman, Jan H Koeman, Abraham Brouwer. Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat. Toxicological sciences : an official journal of the Society of Toxicology. 2002 Aug; 68(2):361-71. doi: 10.1093/toxsci/68.2.361. [PMID: 12151632]
  • S Hallgren, T Sinjari, H Håkansson, P O Darnerud. Effects of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) on thyroid hormone and vitamin A levels in rats and mice. Archives of toxicology. 2001 Jun; 75(4):200-8. doi: 10.1007/s002040000208. [PMID: 11482517]
  • M Haag-Grönlund, N Johansson, R Fransson-Steen, H Hâkansson, G Scheu, L Wärngård. Interactive effects of three structurally different polychlorinated biphenyls in a rat liver tumor promotion bioassay. Toxicology and applied pharmacology. 1998 Sep; 152(1):153-65. doi: 10.1006/taap.1998.8480. [PMID: 9772211]
  • I Chu, R Poon, A Yagminas, P Lecavalier, H Håkansson, V E Valli, S W Kennedy, A Bergman, R F Seegal, M Feeley. Subchronic toxicity of PCB 105 (2,3,3',4,4'-pentachlorobiphenyl) in rats. Journal of applied toxicology : JAT. 1998 Jul; 18(4):285-92. doi: 10.1002/(sici)1099-1263(199807/08)18:4<285::aid-jat510>3.0.co;2-9. [PMID: 9719429]
  • K Ingebrigtsen, H Hektoen, T Andersson, A Bergman, I Brandt. Species-specific accumulation of the polychlorinated biphenyl (PCB) 2,3,3',4,4'-pentachlorobiphenyl in fish brain: a comparison between cod (Gadus morhua) and rainbow trout (Oncorhynchus mykiss). Pharmacology & toxicology. 1990 Oct; 67(4):344-5. doi: 10.1111/j.1600-0773.1990.tb00842.x. [PMID: 2127636]