1,2,3,6,7,8-Hexachlorodibenzo-P-dioxin (BioDeep_00000012076)

 

Secondary id: BioDeep_00001868175

human metabolite blood metabolite


代谢物信息卡片


1,2,3,6,7,8-HEXACHLORODIBENZO-P-DIOXIN

化学式: C12H2Cl6O2 (387.8185972)
中文名称: 1,2,3,6,7,8-六氯二苯并-对-二恶英
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=C2C(=C(C(=C1Cl)Cl)Cl)OC3=CC(=C(C(=C3O2)Cl)Cl)Cl
InChI: InChI=1S/C12H2Cl6O2/c13-3-1-5-11(9(17)7(3)15)20-6-2-4(14)8(16)10(18)12(6)19-5/h1-2H

描述信息

D009676 - Noxae > D013723 - Teratogens > D000072317 - Polychlorinated Dibenzodioxins

同义名列表

6 个代谢物同义名

1,2,3,6,7,8-HEXACHLORODIBENZO-P-DIOXIN; 1,2,3,6,7,8-Hexachlorodibenzodioxin; 1,2,3,6,7,8-hexachlorooxanthrene; 1,2,3,6,7,8-HXCDD; PCDD 67; HXCDD



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Richard Y Wang, Ram B Jain, Amy F Wolkin, Carol H Rubin, Larry L Needham. Serum concentrations of selected persistent organic pollutants in a sample of pregnant females and changes in their concentrations during gestation. Environmental health perspectives. 2009 Aug; 117(8):1244-9. doi: 10.1289/ehp.0800105. [PMID: 19672404]
  • Hirokazu Uemura, Kokichi Arisawa, Mineyoshi Hiyoshi, Atsushi Kitayama, Hidenobu Takami, Fusakazu Sawachika, Satoru Dakeshita, Kentaro Nii, Hiroshi Satoh, Yoshio Sumiyoshi, Kenji Morinaga, Kazunori Kodama, Taka-ichiro Suzuki, Masaki Nagai, Tsuguyoshi Suzuki. Prevalence of metabolic syndrome associated with body burden levels of dioxin and related compounds among Japan's general population. Environmental health perspectives. 2009 Apr; 117(4):568-73. doi: 10.1289/ehp.0800012. [PMID: 19440495]
  • Charles J Everett, Ivar L Frithsen, Vanessa A Diaz, Richelle J Koopman, William M Simpson, Arch G Mainous. Association of a polychlorinated dibenzo-p-dioxin, a polychlorinated biphenyl, and DDT with diabetes in the 1999-2002 National Health and Nutrition Examination Survey. Environmental research. 2007 Mar; 103(3):413-8. doi: 10.1016/j.envres.2006.11.002. [PMID: 17187776]
  • Mary S Wolff, Susan L Teitelbaum, Paul J Lioy, Regina M Santella, Richard Y Wang, Robert L Jones, Kathleen L Caldwell, Andreas Sjödin, Wayman E Turner, Wei Li, Panos Georgopoulos, Gertrud S Berkowitz. Exposures among pregnant women near the World Trade Center site on 11 September 2001. Environmental health perspectives. 2005 Jun; 113(6):739-48. doi: 10.1289/ehp.7694. [PMID: 15929898]
  • Chan-Seok Moon, Yoon-Seok Chang, Byung-Hoon Kim, Dongchun Shin, Masayuki Ikeda. Evaluation of serum dioxin congeners among residents near continuously burning municipal solid waste incinerators in Korea. International archives of occupational and environmental health. 2005 Apr; 78(3):205-10. doi: 10.1007/s00420-005-0603-0. [PMID: 15744508]
  • Junya Nagayama, Takumi Takasuga, Hiroshi Tsuji, Motomi Umehara, Takehiko Sada, Teruaki Iwasaki. Active elimination of causative PCDFs/DDs congeners of Yusho by one year intake of FBRA in Japanese people. Fukuoka igaku zasshi = Hukuoka acta medica. 2003 May; 94(5):118-25. doi: ". [PMID: 12872712]
  • O Aozasa, T Tetsumi, S Ohta, T Nakao, H Miyata, T Nomura. Fecal excretion of dioxin in mice enhanced by intake of dietary fiber bearing chlorophyllin. Bulletin of environmental contamination and toxicology. 2003 Feb; 70(2):359-66. doi: 10.1007/s00128-002-0199-y. [PMID: 12545371]
  • Ulla Simanainen, Jouni T Tuomisto, Jouko Tuomisto, Matti Viluksela. Structure-activity relationships and dose responses of polychlorinated dibenzo-p-dioxins for short-term effects in 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant and -sensitive rat strains. Toxicology and applied pharmacology. 2002 May; 181(1):38-47. doi: 10.1006/taap.2002.9386. [PMID: 12030841]
  • S E Rier, W E Turner, D C Martin, R Morris, G W Lucier, G C Clark. Serum levels of TCDD and dioxin-like chemicals in Rhesus monkeys chronically exposed to dioxin: correlation of increased serum PCB levels with endometriosis. Toxicological sciences : an official journal of the Society of Toxicology. 2001 Jan; 59(1):147-59. doi: 10.1093/toxsci/59.1.147. [PMID: 11134554]
  • X Gao, D S Son, P F Terranova, K K Rozman. Toxic equivalency factors of polychlorinated dibenzo-p-dioxins in an ovulation model: validation of the toxic equivalency concept for one aspect of endocrine disruption. Toxicology and applied pharmacology. 1999 Jun; 157(2):107-16. doi: 10.1006/taap.1999.8649. [PMID: 10366543]
  • M Viluksela, B U Stahl, L S Birnbaum, K K Rozman. Subchronic/chronic toxicity of a mixture of four chlorinated dibenzo-p-dioxins in rats. II. Biochemical effects. Toxicology and applied pharmacology. 1998 Jul; 151(1):70-8. doi: 10.1006/taap.1998.8412. [PMID: 9705888]
  • K L White, H H Lysy, J A McCay, A C Anderson. Modulation of serum complement levels following exposure to polychlorinated dibenzo-p-dioxins. Toxicology and applied pharmacology. 1986 Jun; 84(2):209-19. doi: 10.1016/0041-008x(86)90128-6. [PMID: 3715871]
  • G E Striker, L J Quadracci, R E Cutler. Use and interpretation of renal biopsy. Major problems in pathology. 1978; 8(?):1-339. doi: NULL. [PMID: 24154]